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Wyszukujesz frazę ""Mitosis"" wg kryterium: Temat


Tytuł:
Control of cell proliferation by memories of mitosis.
Autorzy:
Meitinger F; Department of Cell and Developmental Biology, School of Biological Sciences, University of California San Diego, La Jolla, CA 92093, USA.; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA 92093, USA.; Ludwig Institute for Cancer Research, La Jolla, CA 92093, USA.; Okinawa Institute of Science and Technology Graduate University, Okinawa 904-0495, Japan.
Belal H; Okinawa Institute of Science and Technology Graduate University, Okinawa 904-0495, Japan.
Davis RL; Small Molecule Discovery Program, Ludwig Institute for Cancer Research, La Jolla, CA 92093, USA.
Martinez MB; Small Molecule Discovery Program, Ludwig Institute for Cancer Research, La Jolla, CA 92093, USA.
Shiau AK; Department of Cell and Developmental Biology, School of Biological Sciences, University of California San Diego, La Jolla, CA 92093, USA.; Small Molecule Discovery Program, Ludwig Institute for Cancer Research, La Jolla, CA 92093, USA.
Oegema K; Department of Cell and Developmental Biology, School of Biological Sciences, University of California San Diego, La Jolla, CA 92093, USA.; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA 92093, USA.; Ludwig Institute for Cancer Research, La Jolla, CA 92093, USA.
Desai A; Department of Cell and Developmental Biology, School of Biological Sciences, University of California San Diego, La Jolla, CA 92093, USA.; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA 92093, USA.; Ludwig Institute for Cancer Research, La Jolla, CA 92093, USA.
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Źródło:
Science (New York, N.Y.) [Science] 2024 Mar 29; Vol. 383 (6690), pp. 1441-1448. Date of Electronic Publication: 2024 Mar 28.
Typ publikacji:
Journal Article
MeSH Terms:
Cell Proliferation*/genetics
Mitosis*/drug effects
Mitosis*/genetics
Neoplasms*/genetics
Neoplasms*/pathology
Ubiquitin Thiolesterase*/genetics
Ubiquitin Thiolesterase*/metabolism
Tumor Suppressor p53-Binding Protein 1*/genetics
Tumor Suppressor p53-Binding Protein 1*/metabolism
Humans ; Genomic Instability ; Tumor Suppressor Protein p53/genetics ; Tumor Suppressor Protein p53/metabolism ; Cell Line, Tumor ; Polo-Like Kinase 1/metabolism ; Antimitotic Agents/pharmacology ; Drug Resistance, Neoplasm
Czasopismo naukowe
Tytuł:
A mitotic stopwatch determines cell fate.
Autorzy:
Bertolin AP; The Francis Crick Institute, London, UK.
Gottifredi V; Fundación Instituto Leloir, Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, Argentina.
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Źródło:
Science (New York, N.Y.) [Science] 2024 Mar 29; Vol. 383 (6690), pp. 1414-1415. Date of Electronic Publication: 2024 Mar 28.
Typ publikacji:
Journal Article; Comment
MeSH Terms:
Mitosis*
Cell Proliferation ; Cell Differentiation
Czasopismo naukowe
Tytuł:
Automatic detection of cell-cycle stages using recurrent neural networks.
Autorzy:
Jose A; Institute of Imaging and Computer Vision, RWTH Aachen University, Aachen, Germany.
Roy R; Institute of Imaging and Computer Vision, RWTH Aachen University, Aachen, Germany.
Moreno-Andrés D; Institute of Biochemistry and Molecular Cell Biology, Medical School, RWTH Aachen University, Aachen, Germany.
Stegmaier J; Institute of Imaging and Computer Vision, RWTH Aachen University, Aachen, Germany.
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Źródło:
PloS one [PLoS One] 2024 Mar 11; Vol. 19 (3), pp. e0297356. Date of Electronic Publication: 2024 Mar 11 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Neural Networks, Computer*
Mitosis*
Czasopismo naukowe
Tytuł:
Phosphatase specificity principles uncovered by MRBLE:Dephos and global substrate identification.
Autorzy:
Hein JB; Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Department of Bioengineering, Stanford University, Stanford, CA, USA.
Nguyen HT; Biochemistry and Cell Biology, Geisel School of Medicine at Dartmouth College, Hanover, NH, USA.
Garvanska DH; Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Nasa I; Department of Bioengineering, Stanford University, Stanford, CA, USA.
Kruse T; Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Feng Y; Department of Genetics, Stanford University, Stanford, CA, USA.
Lopez Mendez B; Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Davey N; Division of Cancer Biology, The Institute of Cancer Research, London, UK.
Kettenbach AN; Biochemistry and Cell Biology, Geisel School of Medicine at Dartmouth College, Hanover, NH, USA.
Fordyce PM; Department of Bioengineering, Stanford University, Stanford, CA, USA.; Department of Genetics, Stanford University, Stanford, CA, USA.; Sarafan ChEM-H, Stanford University, Stanford, CA, USA.; Chan Zuckerberg Biohub, San Francisco, CA, USA.
Nilsson J; Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
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Źródło:
Molecular systems biology [Mol Syst Biol] 2023 Dec 06; Vol. 19 (12), pp. e11782. Date of Electronic Publication: 2023 Nov 02.
Typ publikacji:
Journal Article
MeSH Terms:
Protein Phosphatase 2*/chemistry
Protein Phosphatase 2*/genetics
Protein Phosphatase 2*/metabolism
Mitosis*
Phosphorylation ; Signal Transduction ; Substrate Specificity
Czasopismo naukowe
Tytuł:
Differentiable optimization layers enhance GNN-based mitosis detection.
Autorzy:
Zhang H; Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Chiba, 277-8561, Japan.
Nguyen DH; Department of Computer Science, The University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8577, Japan.
Tsuda K; Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Chiba, 277-8561, Japan. .; RIKEN Center for Advanced Intelligence Project, 1-4-1 Nihonbashi, Chuo-ku, Tokyo, 103-0027, Japan. .; Research and Services Division of Materials Data and Integrated System, National Institute for Materials Science, Tsukuba, Ibaraki, 305-0047, Japan. .
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Źródło:
Scientific reports [Sci Rep] 2023 Aug 31; Vol. 13 (1), pp. 14306. Date of Electronic Publication: 2023 Aug 31.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Mitosis*
Cell Nucleus Division*
Neural Networks, Computer ; Algorithms ; Knowledge
Czasopismo naukowe
Tytuł:
RHINO directs MMEJ to repair DNA breaks in mitosis.
Autorzy:
Brambati A; Molecular Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Sacco O; Molecular Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Porcella S; Molecular Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Heyza J; Institute for Quantitative Health Sciences and Engineering, Michigan State University, East Lansing, MI, USA.; Department of Obstetrics, Gynecology, and Reproductive Biology, Michigan State University, East Lansing, MI, USA.
Kareh M; Molecular Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Schmidt JC; Institute for Quantitative Health Sciences and Engineering, Michigan State University, East Lansing, MI, USA.; Department of Obstetrics, Gynecology, and Reproductive Biology, Michigan State University, East Lansing, MI, USA.
Sfeir A; Molecular Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
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Źródło:
Science (New York, N.Y.) [Science] 2023 Aug 11; Vol. 381 (6658), pp. 653-660. Date of Electronic Publication: 2023 Jul 13.
Typ publikacji:
Journal Article
MeSH Terms:
Cell Cycle Proteins*/genetics
Cell Cycle Proteins*/metabolism
DNA Breaks, Double-Stranded*
DNA End-Joining Repair*
Exonucleases*/genetics
Exonucleases*/metabolism
Mitosis*/genetics
Humans ; HEK293 Cells ; Poly(ADP-ribose) Polymerases/metabolism
Czasopismo naukowe
Tytuł:
MAPK-dependent control of mitotic progression in S. pombe.
Autorzy:
Iglesias-Romero AB; Centro Andaluz de Biología del Desarrollo, Universidad Pablo de Olavide, Seville, 41013, Spain.
Soto T; Yeast Physiology Group, Department of Genetics and Microbiology, Facultad de Biología, Universidad de Murcia, Murcia, 30071, Spain.
Flor-Parra I; Centro Andaluz de Biología del Desarrollo, Universidad Pablo de Olavide, Seville, 41013, Spain.
Salas-Pino S; Centro Andaluz de Biología del Desarrollo, Universidad Pablo de Olavide, Seville, 41013, Spain.
Ruiz-Romero G; Centro Andaluz de Biología del Desarrollo, Universidad Pablo de Olavide, Seville, 41013, Spain.
Gould KL; Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN, 37240, USA.
Cansado J; Yeast Physiology Group, Department of Genetics and Microbiology, Facultad de Biología, Universidad de Murcia, Murcia, 30071, Spain. .
Daga RR; Centro Andaluz de Biología del Desarrollo, Universidad Pablo de Olavide, Seville, 41013, Spain. .
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Źródło:
BMC biology [BMC Biol] 2024 Mar 25; Vol. 22 (1), pp. 71. Date of Electronic Publication: 2024 Mar 25.
Typ publikacji:
Journal Article
MeSH Terms:
Schizosaccharomyces*/genetics
Schizosaccharomyces*/metabolism
Schizosaccharomyces pombe Proteins*/genetics
Schizosaccharomyces pombe Proteins*/metabolism
Anaphase-Promoting Complex-Cyclosome/genetics ; Anaphase-Promoting Complex-Cyclosome/metabolism ; Cdc20 Proteins/genetics ; Cdc20 Proteins/metabolism ; Cell Cycle Proteins/metabolism ; Mitosis ; Spindle Apparatus/metabolism
Czasopismo naukowe
Tytuł:
Recombinant cyclin B-Cdk1-Suc1 capable of multi-site mitotic phosphorylation in vitro.
Autorzy:
Shintomi K; Chromosome Dynamics Laboratory, RIKEN Cluster for Pioneering Research, Wako, Saitama, Japan.
Masahara-Negishi Y; Chromosome Dynamics Laboratory, RIKEN Cluster for Pioneering Research, Wako, Saitama, Japan.
Shima M; Chromosome Dynamics Laboratory, RIKEN Cluster for Pioneering Research, Wako, Saitama, Japan.
Tane S; Chromosome Dynamics Laboratory, RIKEN Cluster for Pioneering Research, Wako, Saitama, Japan.
Hirano T; Chromosome Dynamics Laboratory, RIKEN Cluster for Pioneering Research, Wako, Saitama, Japan.
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Źródło:
PloS one [PLoS One] 2024 Mar 25; Vol. 19 (3), pp. e0299003. Date of Electronic Publication: 2024 Mar 25 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
CDC2 Protein Kinase*/metabolism
Cyclin B*/genetics
Cyclin B*/metabolism
Phosphorylation ; Proteins/metabolism ; Mitosis
Czasopismo naukowe
Tytuł:
The oncogene cyclin D1 promotes bipolar spindle integrity under compressive force.
Autorzy:
Sutanto R; Department of Bioengineering & Therapeutic Sciences, University of California San Francisco, San Francisco, California, United States of America.
Neahring L; Department of Bioengineering & Therapeutic Sciences, University of California San Francisco, San Francisco, California, United States of America.; Developmental & Stem Cell Biology Graduate Program, University of California San Francisco, San Francisco, California, United States of America.
Serra Marques A; Department of Bioengineering & Therapeutic Sciences, University of California San Francisco, San Francisco, California, United States of America.
Jacobo Jacobo M; Department of Bioengineering & Therapeutic Sciences, University of California San Francisco, San Francisco, California, United States of America.; Department of Cell & Tissue Biology, University of California San Francisco, San Francisco, California, United States of America.; Pharmaceutical Sciences and Pharmacogenomics Graduate Program, University of California San Francisco, San Francisco, California, United States of America.
Kilinc S; Department of Cell & Tissue Biology, University of California San Francisco, San Francisco, California, United States of America.
Goga A; Department of Cell & Tissue Biology, University of California San Francisco, San Francisco, California, United States of America.; Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, California, United States of America.; Department of Medicine, University of California San Francisco, San Francisco, California, United States of America.
Dumont S; Department of Bioengineering & Therapeutic Sciences, University of California San Francisco, San Francisco, California, United States of America.; Developmental & Stem Cell Biology Graduate Program, University of California San Francisco, San Francisco, California, United States of America.; Department of Biochemistry & Biophysics, University of California San Francisco, San Francisco, California, United States of America.; Chan Zuckerberg Biohub, San Francisco, California, United States of America.
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Źródło:
PloS one [PLoS One] 2024 Mar 13; Vol. 19 (3), pp. e0296779. Date of Electronic Publication: 2024 Mar 13 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Centrosome*
Cyclin D1*/genetics
Humans ; Centrioles ; Mitosis ; Oncogenes ; Spindle Apparatus/genetics
Czasopismo naukowe
Tytuł:
Functional characterization of D-type cyclins involved in cell division in rice.
Autorzy:
Jiang Z; Key Laboratory of Crop Physiology, Ecology, and Genetic Breeding of the Ministry of Education, Jiangxi Agricultural University, Nanchang, Jiangxi, China.
Wang X; Jiangxi Province Forest Resources Protection Center, Nanchang, 330008, Jiangxi, China.
Zhou Z; Key Laboratory of Crop Physiology, Ecology, and Genetic Breeding of the Ministry of Education, Jiangxi Agricultural University, Nanchang, Jiangxi, China.
Peng L; Key Laboratory of Crop Physiology, Ecology, and Genetic Breeding of the Ministry of Education, Jiangxi Agricultural University, Nanchang, Jiangxi, China.
Lin X; Key Laboratory of Crop Physiology, Ecology, and Genetic Breeding of the Ministry of Education, Jiangxi Agricultural University, Nanchang, Jiangxi, China.
Luo X; Key Laboratory of Crop Physiology, Ecology, and Genetic Breeding of the Ministry of Education, Jiangxi Agricultural University, Nanchang, Jiangxi, China.
Song Y; Key Laboratory of Crop Physiology, Ecology, and Genetic Breeding of the Ministry of Education, Jiangxi Agricultural University, Nanchang, Jiangxi, China.
Ning H; Key Laboratory of Crop Physiology, Ecology, and Genetic Breeding of the Ministry of Education, Jiangxi Agricultural University, Nanchang, Jiangxi, China.
Gan C; Key Laboratory of Crop Physiology, Ecology, and Genetic Breeding of the Ministry of Education, Jiangxi Agricultural University, Nanchang, Jiangxi, China.
He X; Key Laboratory of Crop Physiology, Ecology, and Genetic Breeding of the Ministry of Education, Jiangxi Agricultural University, Nanchang, Jiangxi, China.
Zhu C; Key Laboratory of Crop Physiology, Ecology, and Genetic Breeding of the Ministry of Education, Jiangxi Agricultural University, Nanchang, Jiangxi, China.
Ouyang L; Key Laboratory of Crop Physiology, Ecology, and Genetic Breeding of the Ministry of Education, Jiangxi Agricultural University, Nanchang, Jiangxi, China.
Zhou D; Key Laboratory of Crop Physiology, Ecology, and Genetic Breeding of the Ministry of Education, Jiangxi Agricultural University, Nanchang, Jiangxi, China.
Cai Y; Key Laboratory of Crop Physiology, Ecology, and Genetic Breeding of the Ministry of Education, Jiangxi Agricultural University, Nanchang, Jiangxi, China.
Xu J; Key Laboratory of Crop Physiology, Ecology, and Genetic Breeding of the Ministry of Education, Jiangxi Agricultural University, Nanchang, Jiangxi, China. .
He H; Key Laboratory of Crop Physiology, Ecology, and Genetic Breeding of the Ministry of Education, Jiangxi Agricultural University, Nanchang, Jiangxi, China. .
Liu Y; Key Laboratory of Crop Physiology, Ecology, and Genetic Breeding of the Ministry of Education, Jiangxi Agricultural University, Nanchang, Jiangxi, China. .
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Źródło:
BMC plant biology [BMC Plant Biol] 2024 Mar 01; Vol. 24 (1), pp. 157. Date of Electronic Publication: 2024 Mar 01.
Typ publikacji:
Journal Article
MeSH Terms:
Cyclins*/genetics
Cyclins*/metabolism
Oryza*/genetics
Oryza*/metabolism
Phosphorylation ; Cyclin-Dependent Kinases/genetics ; Cyclin-Dependent Kinases/metabolism ; Cell Cycle/genetics ; Retinoblastoma Protein/genetics ; Retinoblastoma Protein/metabolism ; Mitosis
Czasopismo naukowe
Tytuł:
Expression of the checkpoint kinase BUB1 is a predictor of response to cancer therapies.
Autorzy:
Cicirò Y; Centre for Inflammation Research and Translational Medicine (CIRTM), Brunel University London, Uxbridge, UB8 3PH, UK.
Ragusa D; Centre for Genome Engineering and Maintenance (CenGEM), Brunel University London, Uxbridge, UB8 3PH, UK. .
Sala A; Centre for Inflammation Research and Translational Medicine (CIRTM), Brunel University London, Uxbridge, UB8 3PH, UK. .
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Źródło:
Scientific reports [Sci Rep] 2024 Feb 23; Vol. 14 (1), pp. 4461. Date of Electronic Publication: 2024 Feb 23.
Typ publikacji:
Journal Article
MeSH Terms:
Protein Serine-Threonine Kinases*/metabolism
Neoplasms*/drug therapy
Neoplasms*/genetics
Humans ; Mitosis/genetics ; Cell Cycle Proteins/genetics ; Cell Cycle Proteins/metabolism
Czasopismo naukowe
Tytuł:
The Pleiotropic Ubiquitin-Specific Peptidase 16 and Its Many Substrates.
Autorzy:
Zheng J; Department of Internal Medicine, Division of Hematology, Oncology, and Palliative Care, Massey Cancer Center, School of Medicine, Virginia Commonwealth University, Richmond, VA 23298, USA.; Department of Obstetrics and Gynecology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong 999077, China.
Chen C; Department of Bioengineering, School of Engineering, Virginia Commonwealth University, Richmond, VA 23298, USA.
Guo C; Department of Human and Molecular Genetics, School of Medicine, Virginia Commonwealth University, Richmond, VA 23298, USA.
Caba C; Department of Chemistry and Biochemistry, University of Windsor, Windsor, ON N9B 3P4, Canada.
Tong Y; Department of Chemistry and Biochemistry, University of Windsor, Windsor, ON N9B 3P4, Canada.
Wang H; Department of Internal Medicine, Division of Hematology, Oncology, and Palliative Care, Massey Cancer Center, School of Medicine, Virginia Commonwealth University, Richmond, VA 23298, USA.
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Źródło:
Cells [Cells] 2023 Mar 13; Vol. 12 (6). Date of Electronic Publication: 2023 Mar 13.
Typ publikacji:
Journal Article; Review; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, Non-U.S. Gov't
MeSH Terms:
Histones*/metabolism
Mitosis*
Humans ; Male ; DNA Repair ; Ubiquitin-Specific Proteases/metabolism ; Deubiquitinating Enzymes/metabolism
Czasopismo naukowe
Tytuł:
Kinesins Modify ERR1-Dependent Transcription Using a Conserved Nuclear Receptor Box Motif.
Autorzy:
Seneviratne AMPB; CUNY School of Medicine, City College of New York, New York, NY 10031, USA.; Department of Molecular, Cellular and Biomedical Sciences, CUNY School of Medicine, City College of New York, New York, NY 10031, USA.
Lidagoster S; CUNY School of Medicine, City College of New York, New York, NY 10031, USA.
Valbuena-Castor S; CUNY School of Medicine, City College of New York, New York, NY 10031, USA.
Lashley K; CUNY School of Medicine, City College of New York, New York, NY 10031, USA.
Saha S; CUNY School of Medicine, City College of New York, New York, NY 10031, USA.
Alimova A; CUNY School of Medicine, City College of New York, New York, NY 10031, USA.; Department of Molecular, Cellular and Biomedical Sciences, CUNY School of Medicine, City College of New York, New York, NY 10031, USA.
Kreitzer G; CUNY School of Medicine, City College of New York, New York, NY 10031, USA.; Department of Molecular, Cellular and Biomedical Sciences, CUNY School of Medicine, City College of New York, New York, NY 10031, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Feb 14; Vol. 24 (4). Date of Electronic Publication: 2023 Feb 14.
Typ publikacji:
Journal Article
MeSH Terms:
Gene Expression Regulation*
Kinesins*/metabolism
Mitosis*
Receptors, Estrogen*/genetics
Receptors, Estrogen*/metabolism
Cell Nucleus/metabolism ; Microtubules/metabolism ; Amino Acid Motifs/genetics
Czasopismo naukowe
Tytuł:
SH2D4A promotes centrosome maturation to support spindle microtubule formation and mitotic progression.
Autorzy:
Yuki R; Department of Biochemistry & Molecular Biology, Kyoto Pharmaceutical University, 5 Misasagi-Nakauchi-cho, Yamashina-ku, Kyoto, 607-8414, Japan. .
Ikeda Y; Department of Biochemistry & Molecular Biology, Kyoto Pharmaceutical University, 5 Misasagi-Nakauchi-cho, Yamashina-ku, Kyoto, 607-8414, Japan.
Yasutake R; Department of Biochemistry & Molecular Biology, Kyoto Pharmaceutical University, 5 Misasagi-Nakauchi-cho, Yamashina-ku, Kyoto, 607-8414, Japan.
Saito Y; Department of Biochemistry & Molecular Biology, Kyoto Pharmaceutical University, 5 Misasagi-Nakauchi-cho, Yamashina-ku, Kyoto, 607-8414, Japan.
Nakayama Y; Department of Biochemistry & Molecular Biology, Kyoto Pharmaceutical University, 5 Misasagi-Nakauchi-cho, Yamashina-ku, Kyoto, 607-8414, Japan. .
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Źródło:
Scientific reports [Sci Rep] 2023 Feb 04; Vol. 13 (1), pp. 2067. Date of Electronic Publication: 2023 Feb 04.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Centrosome*/metabolism
Mitosis*
Humans ; Chromosomal Proteins, Non-Histone/metabolism ; Intracellular Signaling Peptides and Proteins/metabolism ; Microtubules/metabolism ; Spindle Apparatus/metabolism ; Tubulin/metabolism
Czasopismo naukowe
Tytuł:
CHIR99021, trough GSK-3β Targeting, Reduces Epithelioid Sarcoma Cell Proliferation by Activating Mitotic Catastrophe and Autophagy.
Autorzy:
Russi S; IRCCS CROB-Referral Cancer Center of Basilicata, 85028 Rionero in Vulture, Italy.
Sgambato A; IRCCS CROB-Referral Cancer Center of Basilicata, 85028 Rionero in Vulture, Italy.
Bochicchio AM; IRCCS CROB-Referral Cancer Center of Basilicata, 85028 Rionero in Vulture, Italy.
Zoppoli P; IRCCS CROB-Referral Cancer Center of Basilicata, 85028 Rionero in Vulture, Italy.
Aieta M; IRCCS CROB-Referral Cancer Center of Basilicata, 85028 Rionero in Vulture, Italy.
Capobianco AML; IRCCS CROB-Referral Cancer Center of Basilicata, 85028 Rionero in Vulture, Italy.
Ruggieri V; IRCCS CROB-Referral Cancer Center of Basilicata, 85028 Rionero in Vulture, Italy.; UOC Clinical Pathology, Altamura Hospital, 70022 Altamura, Italy.
Zifarone E; IRCCS CROB-Referral Cancer Center of Basilicata, 85028 Rionero in Vulture, Italy.
Falco G; Department of Biology, University of Naples Federico II, 80133 Naples, Italy.; Biogem-Istituto di Biologia e Genetica Molecolare, 83031 Ariano Irpino, Italy.
Laurino S; IRCCS CROB-Referral Cancer Center of Basilicata, 85028 Rionero in Vulture, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Oct 15; Vol. 22 (20). Date of Electronic Publication: 2021 Oct 15.
Typ publikacji:
Journal Article
MeSH Terms:
Autophagy/*drug effects
Mitosis/*drug effects
Pyridines/*pharmacology
Pyrimidines/*pharmacology
Sarcoma/*pathology
Soft Tissue Neoplasms/*pathology
Adult ; Cell Cycle Checkpoints/drug effects ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Cells, Cultured ; Glycogen Synthase Kinase 3 beta/antagonists & inhibitors ; Glycogen Synthase Kinase 3 beta/physiology ; Humans ; Mitosis Modulators/pharmacology ; Sarcoma/mortality ; Soft Tissue Neoplasms/mortality ; Survival Analysis
Czasopismo naukowe
Tytuł:
Chromosome Inequality: Causes and Consequences of Non-Random Segregation Errors in Mitosis and Meiosis.
Autorzy:
Klaasen SJ; Hubrecht Institute-KNAW (Royal Netherlands Academy of Arts and Sciences) and University Medical Centre Utrecht, 3584 CT Utrecht, The Netherlands.; Oncode Institute, 3521 AL Utrecht, The Netherlands.
Kops GJPL; Hubrecht Institute-KNAW (Royal Netherlands Academy of Arts and Sciences) and University Medical Centre Utrecht, 3584 CT Utrecht, The Netherlands.; Oncode Institute, 3521 AL Utrecht, The Netherlands.
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Źródło:
Cells [Cells] 2022 Nov 11; Vol. 11 (22). Date of Electronic Publication: 2022 Nov 11.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Meiosis*/genetics
Mitosis*/genetics
Animals ; Humans ; Chromosomes ; Chromosome Segregation/genetics ; Aneuploidy ; Mammals/genetics
Czasopismo naukowe
Tytuł:
BP-M345 as a Basis for the Discovery of New Diarylpentanoids with Promising Antimitotic Activity.
Autorzy:
Moreira J; Laboratory of Organic and Pharmaceutical Chemistry, Department of Chemical Sciences, Faculty of Pharmacy, University of Porto, Rua de Jorge Viterbo Ferreira 228, 4050-313 Porto, Portugal.; Interdisciplinary Centre of Marine and Environmental Research (CIIMAR), University of Porto, Edifício do Terminal de Cruzeiros do Porto de Leixões, Avenida General Norton de Matos S/N, 4450-208 Matosinhos, Portugal.
Silva PMA; UNIPRO-Oral Pathology and Rehabilitation Research Unit, University Institute of Health Sciences (IUCS), Cooperativa de Ensino Superior Politécnico e Universitário (CESPU), Rua Central de Gandra 1317, 4585-116 Gandra, Portugal.; 1H-TOXRUN-One Health Toxicology Research Unit, University Institute of Health Sciences (IUCS), Cooperativa de Ensino Superior Politécnico e Universitário (CESPU), Rua Central de Gandra 1317, 4585-116 Gandra, Portugal.
Castro E; UNIPRO-Oral Pathology and Rehabilitation Research Unit, University Institute of Health Sciences (IUCS), Cooperativa de Ensino Superior Politécnico e Universitário (CESPU), Rua Central de Gandra 1317, 4585-116 Gandra, Portugal.
Saraiva L; LAQV/REQUIMTE, Laboratory of Microbiology, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, Rua de Jorge Viterbo Ferreira 228, 4050-313 Porto, Portugal.
Pinto M; Laboratory of Organic and Pharmaceutical Chemistry, Department of Chemical Sciences, Faculty of Pharmacy, University of Porto, Rua de Jorge Viterbo Ferreira 228, 4050-313 Porto, Portugal.; Interdisciplinary Centre of Marine and Environmental Research (CIIMAR), University of Porto, Edifício do Terminal de Cruzeiros do Porto de Leixões, Avenida General Norton de Matos S/N, 4450-208 Matosinhos, Portugal.
Bousbaa H; UNIPRO-Oral Pathology and Rehabilitation Research Unit, University Institute of Health Sciences (IUCS), Cooperativa de Ensino Superior Politécnico e Universitário (CESPU), Rua Central de Gandra 1317, 4585-116 Gandra, Portugal.
Cidade H; Laboratory of Organic and Pharmaceutical Chemistry, Department of Chemical Sciences, Faculty of Pharmacy, University of Porto, Rua de Jorge Viterbo Ferreira 228, 4050-313 Porto, Portugal.; Interdisciplinary Centre of Marine and Environmental Research (CIIMAR), University of Porto, Edifício do Terminal de Cruzeiros do Porto de Leixões, Avenida General Norton de Matos S/N, 4450-208 Matosinhos, Portugal.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 30; Vol. 25 (3). Date of Electronic Publication: 2024 Jan 30.
Typ publikacji:
Journal Article
MeSH Terms:
Antimitotic Agents*/pharmacology
Neoplasms*/metabolism
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/metabolism
Humans ; Mitosis ; Cell Proliferation ; Cell Cycle ; Spindle Apparatus/metabolism ; Apoptosis ; Cell Line, Tumor
Czasopismo naukowe
Tytuł:
Enhancing mitosis quantification and detection in meningiomas with computational digital pathology.
Autorzy:
Gu H; Electrical and Computer Engineering, University of California, Los Angeles, Los Angeles, CA, 90095, USA.
Yang C; Electrical and Computer Engineering, University of California, Los Angeles, Los Angeles, CA, 90095, USA.
Al-Kharouf I; Pathology and Laboratory Medicine, The University of Kansas Medical Center, Kansas City, KS, 66160, USA.
Magaki S; Pathology and Laboratory Medicine, UCLA David Geffen School of Medicine, Los Angeles, CA, 90095, USA.
Lakis N; Pathology and Laboratory Medicine, The University of Kansas Medical Center, Kansas City, KS, 66160, USA.
Williams CK; Pathology and Laboratory Medicine, UCLA David Geffen School of Medicine, Los Angeles, CA, 90095, USA.
Alrosan SM; Pathology and Laboratory Medicine, The University of Kansas Medical Center, Kansas City, KS, 66160, USA.
Onstott EK; Pathology and Laboratory Medicine, The University of Kansas Medical Center, Kansas City, KS, 66160, USA.
Yan W; Electrical and Computer Engineering, University of California, Los Angeles, Los Angeles, CA, 90095, USA.
Khanlou N; Pathology and Laboratory Medicine, UCLA David Geffen School of Medicine, Los Angeles, CA, 90095, USA.
Cobos I; Department of Pathology, Stanford Medical School, Stanford, CA, 94305, USA.
Zhang XR; McGovern Medical School, UT Health at Houston, Houston, TX, 77030, USA.
Zarrin-Khameh N; Baylor College of Medicine, Houston, TX, 77030, USA.
Vinters HV; Pathology and Laboratory Medicine, UCLA David Geffen School of Medicine, Los Angeles, CA, 90095, USA.
Chen XA; Electrical and Computer Engineering, University of California, Los Angeles, Los Angeles, CA, 90095, USA. .
Haeri M; Pathology and Laboratory Medicine, The University of Kansas Medical Center, Kansas City, KS, 66160, USA. .
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Źródło:
Acta neuropathologica communications [Acta Neuropathol Commun] 2024 Jan 11; Vol. 12 (1), pp. 7. Date of Electronic Publication: 2024 Jan 11.
Typ publikacji:
Journal Article
MeSH Terms:
Meningioma*/pathology
Meningeal Neoplasms*/pathology
Humans ; Mitotic Index/methods ; Artificial Intelligence ; Mitosis
Czasopismo naukowe
Tytuł:
RIT1 regulates mitosis and promotes proliferation by interacting with SMC3 and PDS5 in hepatocellular carcinoma.
Autorzy:
Su Y; State Key Laboratory of Systems Medicine for Cancer, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200032, China.
Lin H; State Key Laboratory of Systems Medicine for Cancer, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200032, China.
Yu J; State Key Laboratory of Systems Medicine for Cancer, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200032, China.
Mao L; State Key Laboratory of Systems Medicine for Cancer, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200032, China.
Jin W; Department of Oncology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, 200072, China.
Liu T; Department of Oncology, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200127, China.
Jiang S; State Key Laboratory of Systems Medicine for Cancer, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200032, China.
Wu Y; State Key Laboratory of Systems Medicine for Cancer, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200032, China.
Zhang S; State Key Laboratory of Systems Medicine for Cancer, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200032, China.
Geng Q; State Key Laboratory of Systems Medicine for Cancer, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200032, China.
Ge C; State Key Laboratory of Systems Medicine for Cancer, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200032, China.
Zhao F; State Key Laboratory of Systems Medicine for Cancer, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200032, China.
Chen T; Qidong Liver Cancer Institute, Qidong, 226200, China.
Cui Y; Cancer Institute of Guangxi, Nanning, 530021, China.
Li J; State Key Laboratory of Systems Medicine for Cancer, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200032, China.
Hou H; Precision Medicine Center of Oncology, The Affiliated Hospital of Qingdao University, Qingdao, 266003, China. .
Zhou X; Department of Oncology, Huashan Hospital, Fudan University, Shanghai, 200040, China. .
Li H; State Key Laboratory of Systems Medicine for Cancer, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200032, China. .
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Źródło:
Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2023 Nov 29; Vol. 42 (1), pp. 326. Date of Electronic Publication: 2023 Nov 29.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Hepatocellular*/pathology
Liver Neoplasms*/pathology
Animals ; Mice ; Humans ; Mice, Nude ; Cell Proliferation/genetics ; Mitosis ; Gene Expression Regulation, Neoplastic ; Cell Line, Tumor ; Chromosomal Proteins, Non-Histone/metabolism ; Chondroitin Sulfate Proteoglycans/genetics ; Chondroitin Sulfate Proteoglycans/metabolism ; Cell Cycle Proteins/genetics ; ras Proteins/metabolism
Czasopismo naukowe
Tytuł:
Germline study points to sarcoma pathways.
Autorzy:
Mandelker D; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Ladanyi M; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
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Źródło:
Science (New York, N.Y.) [Science] 2023 Jan 20; Vol. 379 (6629), pp. 238-239. Date of Electronic Publication: 2023 Jan 19.
Typ publikacji:
Journal Article
MeSH Terms:
Mitosis*/genetics
Sarcoma*/genetics
Genetic Predisposition to Disease*
Humans ; Germ Cells ; Germ-Line Mutation
Czasopismo naukowe

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