- Tytuł:
-
Bone marrow stromal cells from low-turnover osteoporotic mouse model are less sensitive to the osteogenic effects of
fluvastatin . - Autorzy:
- Źródło:
- PloS one [PLoS One] 2018 Aug 24; Vol. 13 (8), pp. e0202857. Date of Electronic Publication: 2018 Aug 24 (Print Publication: 2018).
- Typ publikacji:
- Journal Article
- MeSH Terms:
-
Fluvastatin /*pharmacology
Mesenchymal Stem Cells/*cytology
Mesenchymal Stem Cells/*drug effects
Osteogenesis/*drug effects
Osteoporosis/*pathology
Alkaline Phosphatase/metabolism ; Animals ; Bone Morphogenetic Protein 2/genetics ; Bone Morphogenetic Protein 2/metabolism ; Calcification, Physiologic/drug effects ; Cell Differentiation/drug effects ; Cell Proliferation/drug effects ; Core Binding Factor Alpha 1 Subunit/genetics ; Core Binding Factor Alpha 1 Subunit/metabolism ; Disease Models, Animal ; Dose-Response Relationship, Drug ; Enzyme Activation/drug effects ; Gene Expression Regulation/drug effects ; Male ; Mesenchymal Stem Cells/metabolism ; Mice ; Osteoblasts/drug effects ; Osteoblasts/metabolism ; Osteoblasts/pathology ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; rhoA GTP-Binding Protein/metabolism
Czasopismo naukowe