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Wyświetlanie 1-20 z 175888
Tytuł:
Generative models of morphogenesis in developmental biology.
Autorzy:
Stillman NR; Department of Cell and Developmental Biology, University College London, Gower Street, London WC1E 6BT, UK. Electronic address: .
Mayor R; Department of Cell and Developmental Biology, University College London, Gower Street, London WC1E 6BT, UK; Center for Integrative Biology, Faculty of Sciences, Universidad Mayor; Santiago, Chile Santiago, Chile.. Electronic address: .
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Źródło:
Seminars in cell & developmental biology [Semin Cell Dev Biol] 2023 Sep 30; Vol. 147, pp. 83-90. Date of Electronic Publication: 2023 Feb 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Models, Biological*
Morphogenesis*
Developmental Biology*/methods
Developmental Biology*/trends
Computer Simulation*/trends
Cell Movement ; Machine Learning ; Humans ; Animals
Czasopismo naukowe
Szczegóły
Tytuł:
Alternative lung cell model systems for toxicology testing strategies: Current knowledge and future outlook.
Autorzy:
Moura JA; In Vitro Toxicology Group, Swansea University Medical School, Singleton Park Campus, Swansea, Wales SA2 8PP, UK.
Meldrum K; In Vitro Toxicology Group, Swansea University Medical School, Singleton Park Campus, Swansea, Wales SA2 8PP, UK.
Doak SH; In Vitro Toxicology Group, Swansea University Medical School, Singleton Park Campus, Swansea, Wales SA2 8PP, UK.
Clift MJD; In Vitro Toxicology Group, Swansea University Medical School, Singleton Park Campus, Swansea, Wales SA2 8PP, UK. Electronic address: .
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Źródło:
Seminars in cell & developmental biology [Semin Cell Dev Biol] 2023 Sep 30; Vol. 147, pp. 70-82. Date of Electronic Publication: 2023 Jan 02.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Lung*
Models, Biological*
Animals ; Humans
Czasopismo naukowe
Szczegóły
Tytuł:
A Stochastic Model of Cortical Microtubule Anchoring and Mechanics Provides Regulatory Control of Microtubule Shape.
Autorzy:
Tian TYY; Mathematics, University of British Columbia, 1984 Mathematics Rd, Vancouver, BC, V6T 1Z2, Canada. .
Macdonald CB; Mathematics, University of British Columbia, 1984 Mathematics Rd, Vancouver, BC, V6T 1Z2, Canada.
Cytrynbaum EN; Mathematics, University of British Columbia, 1984 Mathematics Rd, Vancouver, BC, V6T 1Z2, Canada.
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Źródło:
Bulletin of mathematical biology [Bull Math Biol] 2023 Sep 19; Vol. 85 (11), pp. 103. Date of Electronic Publication: 2023 Sep 19.
Typ publikacji:
Journal Article
MeSH Terms:
Mathematical Concepts*
Models, Biological*
Microtubules
Czasopismo naukowe
Szczegóły
Tytuł:
Mathematical Characterization of Private and Public Immune Receptor Sequences.
Autorzy:
Böttcher L; Department of Computational Science and Philosophy, Frankfurt School of Finance and Management, 60322, Frankfurt am Main, Germany. .; Department of Computational Medicine, University of California, Los Angeles, 621 Charles E. Young Dr. S., Los Angeles, 90095-1766, CA, USA. .; Department of Medicine, University of Florida, Gainesville, 32610, FL, USA. .
Wald S; Statistical Physics Group, Centre for Fluid and Complex Systems, Coventry University, Priory Street, Coventry, CV1 5FB, UK.
Chou T; Department of Computational Medicine, University of California, Los Angeles, 621 Charles E. Young Dr. S., Los Angeles, 90095-1766, CA, USA.; Department of Mathematics, University of California, Los Angeles, 520 Portola Plaza, Los Angeles, 90095-1555, CA, USA.
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Źródło:
Bulletin of mathematical biology [Bull Math Biol] 2023 Sep 14; Vol. 85 (10), pp. 102. Date of Electronic Publication: 2023 Sep 14.
Typ publikacji:
Journal Article
MeSH Terms:
Mathematical Concepts*
Models, Biological*
Humans ; Amino Acid Sequence ; B-Lymphocytes ; Models, Statistical
Czasopismo naukowe
Szczegóły
Tytuł:
Towards Optimal Control of Amyloid Fibrillation.
Autorzy:
Wang M; School of Mathematics, Sun Yat-sen University, Guangzhou, 510275, People's Republic of China.
Li G; Fujian Engineering Research Center of New Chinese Lacquer Material, College of Material and Chemical Engineering, Minjiang University, Fuzhou, 350108, People's Republic of China.; Institute of Oceanography, Minjiang University, Fuzhou, 350108, People's Republic of China.
Peng L; College of Mathematics and Data Science, Minjiang University, Fuzhou, 350108, People's Republic of China.
Hong L; School of Mathematics, Sun Yat-sen University, Guangzhou, 510275, People's Republic of China. .
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Źródło:
Bulletin of mathematical biology [Bull Math Biol] 2023 Sep 09; Vol. 85 (10), pp. 99. Date of Electronic Publication: 2023 Sep 09.
Typ publikacji:
Journal Article
MeSH Terms:
Mathematical Concepts*
Models, Biological*
Humans ; Arrhythmias, Cardiac ; Cytoskeleton ; Logistic Models
Czasopismo naukowe
Szczegóły
Tytuł:
A Mathematical Modelling Study of Chemotactic Dynamics in Cell Cultures: The Impact of Spatio-temporal Heterogeneity.
Autorzy:
Ayensa-Jiménez J; Aragon Institute of Engineering Research, University of Zaragoza, Mariano Esquillor, s.n., 50018, Zaragoza, Spain.; Tissue Microenvironment Laboratory (TME Lab), Institute for Health Research Aragón, San Juan Bosco, 13, 50009, Zaragoza, Spain.
Doweidar MH; Aragon Institute of Engineering Research, University of Zaragoza, Mariano Esquillor, s.n., 50018, Zaragoza, Spain.; Mechanical Engineering Department, School of Engineering and Architecture (EINA), University of Zaragoza, María de Luna s.n., 50018, Zaragoza, Spain.
Doblaré M; Aragon Institute of Engineering Research, University of Zaragoza, Mariano Esquillor, s.n., 50018, Zaragoza, Spain.; Mechanical Engineering Department, School of Engineering and Architecture (EINA), University of Zaragoza, María de Luna s.n., 50018, Zaragoza, Spain.; Tissue Microenvironment Laboratory (TME Lab), Institute for Health Research Aragón, San Juan Bosco, 13, 50009, Zaragoza, Spain.; Nanjing Tech University, 30 South Puzhu Road, 211816, Nanjing, China.
Gaffney EA; Wolfson Centre for Mathematical Biology, Mathematical Institute, University of Oxford, Woodstock Road, Oxford, OX2 6GG, UK. .
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Źródło:
Bulletin of mathematical biology [Bull Math Biol] 2023 Sep 08; Vol. 85 (10), pp. 98. Date of Electronic Publication: 2023 Sep 08.
Typ publikacji:
Journal Article
MeSH Terms:
Mathematical Concepts*
Models, Biological*
Bayes Theorem ; Cell Culture Techniques ; Chemotactic Factors
Czasopismo naukowe
Szczegóły
Tytuł:
Modelling the Effect of Matrix Metalloproteinases in Dermal Wound Healing.
Autorzy:
Dari S; School of Mathematical Sciences, University of Nottingham, Nottingham, NG7 2RD, UK. .
Fadai NT; School of Mathematical Sciences, University of Nottingham, Nottingham, NG7 2RD, UK.
O'Dea RD; School of Mathematical Sciences, University of Nottingham, Nottingham, NG7 2RD, UK.
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Źródło:
Bulletin of mathematical biology [Bull Math Biol] 2023 Sep 05; Vol. 85 (10), pp. 96. Date of Electronic Publication: 2023 Sep 05.
Typ publikacji:
Journal Article
MeSH Terms:
Mathematical Concepts*
Models, Biological*
Humans ; Apoptosis ; Wound Healing ; Matrix Metalloproteinases
Czasopismo naukowe
Szczegóły
Tytuł:
Pretty Darn Good Control: When are Approximate Solutions Better than Approximate Models.
Autorzy:
Montealegre-Mora F; University of California Berkeley, Berkeley, USA.
Lapeyrolerie M; University of California Berkeley, Berkeley, USA.
Chapman M; University of California Berkeley, Berkeley, USA.
Keller AG; University of California Berkeley, Berkeley, USA.
Boettiger C; University of California Berkeley, Berkeley, USA. .
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Źródło:
Bulletin of mathematical biology [Bull Math Biol] 2023 Sep 04; Vol. 85 (10), pp. 95. Date of Electronic Publication: 2023 Sep 04.
Typ publikacji:
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Mathematical Concepts*
Models, Biological*
Algorithms ; Fisheries ; Learning
Czasopismo naukowe
Szczegóły
Tytuł:
Probability Distribution of Tree Age for the Simple Birth-Death Process, with Applications to Distributions of Number of Ancestral Lineages and Divergence Times for Pairs of Taxa in a Yule Tree.
Autorzy:
Mulder WH; Department of Chemistry, The University of the West Indies, Mona Campus, Kingston 7, Jamaica. .
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Źródło:
Bulletin of mathematical biology [Bull Math Biol] 2023 Sep 01; Vol. 85 (10), pp. 94. Date of Electronic Publication: 2023 Sep 01.
Typ publikacji:
Journal Article
MeSH Terms:
Mathematical Concepts*
Models, Biological*
Bayes Theorem ; Phylogeny ; Probability
Czasopismo naukowe
Szczegóły
Tytuł:
Investigation of memory influences on bio-heat responses of skin tissue due to various thermal conditions.
Autorzy:
Tiwari R; Department of Mathematics, Nitishwar College, constituent unit of Babasaheb Bhimrao Ambedkar Bihar University, Bihar, India. .; Department of Mathematical Sciences, IIT BHU, Varanasi, India. .
Singhal A; Department of Computational Sciences, School of Sciences, Christ (Deemed to Be University) Delhi NCR, Ghaziabad, Uttar Pradesh, 201003, India.
Kumar R; Department of Mathematics, Kurukshetra University, Kurukshetra, Haryana, India.
Kumar P; Department of Mathematics, Hotilal Ramnath College, Amnour (A constituent unit of Jai Prakash University, Chapra), Bihar, 841401, India.
Ghangas S; Department of Mathematics, MDSD Girls College, Ambala, Haryana, India.
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Źródło:
Theory in biosciences = Theorie in den Biowissenschaften [Theory Biosci] 2023 Sep; Vol. 142 (3), pp. 275-290. Date of Electronic Publication: 2023 Jul 20.
Typ publikacji:
Journal Article
MeSH Terms:
Hot Temperature*
Models, Biological*
Thermal Conductivity ; Skin
Czasopismo naukowe
Szczegóły
Tytuł:
Total and regional microfiber transport characterization in a 15th - Generation human respiratory airway.
Autorzy:
Li J; School of Engineering - Mechanical and Automotive, RMIT University, Bundoora, VIC, Australia.
Ma J; Fusetec 3D Pty Ltd, Adelaide, SA, 5000, Australia.
Dong J; School of Engineering - Mechanical and Automotive, RMIT University, Bundoora, VIC, Australia.
Yang W; Faculty of Architecture, Building and Planning, University of Melbourne, VIC, 3010, Australia.
Tu J; School of Engineering - Mechanical and Automotive, RMIT University, Bundoora, VIC, Australia.
Tian L; School of Engineering - Mechanical and Automotive, RMIT University, Bundoora, VIC, Australia. Electronic address: .
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Źródło:
Computers in biology and medicine [Comput Biol Med] 2023 Sep; Vol. 163, pp. 107180. Date of Electronic Publication: 2023 Jun 13.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Models, Biological*
Lung*
Humans ; Particle Size ; Trachea ; Administration, Inhalation ; Computer Simulation
Czasopismo naukowe
Szczegóły
Tytuł:
An integrated experimental-computational framework to assess the influence of microstructure and material properties on fracture toughness in clinical specimens of human femoral cortical bone.
Autorzy:
Demirtas A; Department of Mechanical Engineering, Villanova University, Villanova, PA, USA.
Taylor EA; Sibley School of Mechanical and Aerospace Engineering, Cornell University, Ithaca, NY, USA.
Gludovatz B; School of Mechanical and Manufacturing Engineering, University of New South Wales (UNSW Sydney), Sydney, NSW, 2052, Australia.
Ritchie RO; Department of Materials Science and Engineering, University of California, Berkeley, CA, 94720, USA.
Donnelly E; Department of Materials Science and Engineering, Cornell University, Ithaca, NY, USA; Musculoskeletal Integrity Program, Weill Cornell Medicine, Research Institute, Hospital for Special Surgery, New York City, NY, USA.
Ural A; Department of Mechanical Engineering, Villanova University, Villanova, PA, USA. Electronic address: .
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Źródło:
Journal of the mechanical behavior of biomedical materials [J Mech Behav Biomed Mater] 2023 Sep; Vol. 145, pp. 106034. Date of Electronic Publication: 2023 Jul 18.
Typ publikacji:
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Models, Biological*
Fractures, Bone*/pathology
Humans ; Finite Element Analysis ; Cortical Bone/pathology ; Bone and Bones/pathology
Czasopismo naukowe
Szczegóły
Tytuł:
The application of organ-on-chip models for the prediction of human pharmacokinetic profiles during drug development.
Autorzy:
Keuper-Navis M; Department of Metabolic Health Research, Netherlands Organisation for Applied Scientific Research (TNO), Leiden, the Netherlands; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, Utrecht, the Netherlands.
Walles M; Pharmacokinetic Sciences, Novartis Institutes for Biomedical Research, Basel, Switzerland.
Poller B; Pharmacokinetic Sciences, Novartis Institutes for Biomedical Research, Basel, Switzerland.
Myszczyszyn A; Faculty of Veterinary Medicine & Regenerative Medicine Center Utrecht (RMCU), Utrecht University, Utrecht, the Netherlands.
van der Made TK; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, Utrecht, the Netherlands.
Donkers J; Department of Metabolic Health Research, Netherlands Organisation for Applied Scientific Research (TNO), Leiden, the Netherlands.
Eslami Amirabadi H; AZAR Innovations, Utrecht, the Netherlands.
Wilmer MJ; Cell4Pharma, Oss, the Netherlands.
Aan S; Stichting Proefdiervrij, Den Haag, the Netherlands.
Spee B; Faculty of Veterinary Medicine & Regenerative Medicine Center Utrecht (RMCU), Utrecht University, Utrecht, the Netherlands.
Masereeuw R; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, Utrecht, the Netherlands.
van de Steeg E; Department of Metabolic Health Research, Netherlands Organisation for Applied Scientific Research (TNO), Leiden, the Netherlands. Electronic address: .
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Źródło:
Pharmacological research [Pharmacol Res] 2023 Sep; Vol. 195, pp. 106853. Date of Electronic Publication: 2023 Jul 18.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Models, Biological*
Drug Development*
Humans ; Biological Availability ; Microphysiological Systems
Czasopismo naukowe
Szczegóły
Tytuł:
Metabolic control analysis as a strategy to identify therapeutic targets, the case of cancer glycolysis.
Autorzy:
Marín-Hernández Á; Departamento de Bioquímica, Instituto Nacional de Cardiología Ignacio Chávez, Mexico City, 14080, Mexico. Electronic address: .
Saavedra E; Departamento de Bioquímica, Instituto Nacional de Cardiología Ignacio Chávez, Mexico City, 14080, Mexico.
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Źródło:
Bio Systems [Biosystems] 2023 Sep; Vol. 231, pp. 104986. Date of Electronic Publication: 2023 Jul 26.
Typ publikacji:
Journal Article
MeSH Terms:
Models, Biological*
Neoplasms*/drug therapy
Neoplasms*/metabolism
Humans ; Glycolysis ; Hexokinase/metabolism ; Kinetics
Czasopismo naukowe
Szczegóły
Tytuł:
Minimizing enzyme mass to decompose flux distribution for identifying biologically relevant elementary flux modes.
Autorzy:
Chen J; School of Computer and Electronics Information, Guangxi University, Nanning, 530004, China.
Huang Y; School of Computer and Electronics Information, Guangxi University, Nanning, 530004, China; Guangxi Key Laboratory of Multimedia Communications Network Technology, Nanning, 530004, China. Electronic address: .
Zhong C; School of Computer and Electronics Information, Guangxi University, Nanning, 530004, China; Guangxi Key Laboratory of Multimedia Communications Network Technology, Nanning, 530004, China.
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Źródło:
Bio Systems [Biosystems] 2023 Sep; Vol. 231, pp. 104981. Date of Electronic Publication: 2023 Jul 11.
Typ publikacji:
Journal Article
MeSH Terms:
Algorithms*
Models, Biological*
Metabolic Networks and Pathways ; Systems Biology/methods ; Escherichia coli/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
Damage and Fracture Mechanics of Porcine Subcutaneous Tissue Under Tensile Loading.
Autorzy:
Sree VD; School of Mechanical Engineering, Purdue University, West Lafayette, USA.
Toaquiza-Tubon JD; School of Mechanical Engineering, Purdue University, West Lafayette, USA.
Payne J; School of Mechanical Engineering, Purdue University, West Lafayette, USA.
Solorio L; School of Mechanical Engineering, Purdue University, West Lafayette, USA.
Tepole AB; School of Mechanical Engineering, Purdue University, West Lafayette, USA. .
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Źródło:
Annals of biomedical engineering [Ann Biomed Eng] 2023 Sep; Vol. 51 (9), pp. 2056-2069. Date of Electronic Publication: 2023 May 26.
Typ publikacji:
Journal Article
MeSH Terms:
Subcutaneous Tissue*
Models, Biological*
Swine ; Animals ; Injections, Subcutaneous ; Biomechanical Phenomena ; Finite Element Analysis ; Stress, Mechanical
Czasopismo naukowe
Szczegóły
Tytuł:
Application of population physiologically based pharmacokinetic modelling to optimize target expression and clearance mechanisms of therapeutic monoclonal antibodies.
Autorzy:
Reig-Lopez J; Pharmacy and Pharmaceutical Technology and Parasitology Department, Faculty of Pharmacy, University of Valencia, Valencia, Spain.; Clinical Pharmacology and Quantitative Pharmacology, Clinical Pharmacology and Safety Sciences, R&D, AstraZeneca, Cambridge, UK.
Tang W; Clinical Pharmacology and Quantitative Pharmacology, Clinical Pharmacology and Safety Sciences, R&D, AstraZeneca, Gaithersburg, Maryland, USA.
Fernandez-Teruel C; Clinical Pharmacology and Quantitative Pharmacology, Clinical Pharmacology and Safety Sciences, R&D, AstraZeneca, Cambridge, UK.
Merino-Sanjuan M; Pharmacy and Pharmaceutical Technology and Parasitology Department, Faculty of Pharmacy, University of Valencia, Valencia, Spain.; Interuniversity Research Institute for Molecular Recognition and Technological Development, Polytechnic University of Valencia-University of Valencia, Valencia, Spain.
Mangas-Sanjuan V; Pharmacy and Pharmaceutical Technology and Parasitology Department, Faculty of Pharmacy, University of Valencia, Valencia, Spain.; Interuniversity Research Institute for Molecular Recognition and Technological Development, Polytechnic University of Valencia-University of Valencia, Valencia, Spain.
Boulton DW; Clinical Pharmacology and Quantitative Pharmacology, Clinical Pharmacology and Safety Sciences, R&D, AstraZeneca, Gaithersburg, Maryland, USA.
Sharma P; Clinical Pharmacology and Quantitative Pharmacology, Clinical Pharmacology and Safety Sciences, R&D, AstraZeneca, Cambridge, UK.
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Źródło:
British journal of clinical pharmacology [Br J Clin Pharmacol] 2023 Sep; Vol. 89 (9), pp. 2691-2702. Date of Electronic Publication: 2023 May 01.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antibodies, Monoclonal*/pharmacokinetics
Models, Biological*
Humans ; Kinetics ; Computer Simulation ; Trastuzumab ; Cetuximab
Czasopismo naukowe
Szczegóły
Tytuł:
A Quantitative Prediction Method for the Human Pharmacokinetics of Fc-Fusion Proteins.
Autorzy:
Yokoyama M; Drug Metabolism and Pharmacokinetics Research Laboratories, Daiichi Sankyo Co., Ltd., 1-2-58, Hiromachi, Shinagawa-ku, Tokyo, 140-8710, Japan. .
Suzuki E; Drug Metabolism and Pharmacokinetics Research Laboratories, Daiichi Sankyo Co., Ltd., 1-2-58, Hiromachi, Shinagawa-ku, Tokyo, 140-8710, Japan.
Oitate M; Drug Metabolism and Pharmacokinetics Research Laboratories, Daiichi Sankyo Co., Ltd., 1-2-58, Hiromachi, Shinagawa-ku, Tokyo, 140-8710, Japan.
Watanabe N; Drug Metabolism and Pharmacokinetics Research Laboratories, Daiichi Sankyo Co., Ltd., 1-2-58, Hiromachi, Shinagawa-ku, Tokyo, 140-8710, Japan.
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Źródło:
European journal of drug metabolism and pharmacokinetics [Eur J Drug Metab Pharmacokinet] 2023 Sep; Vol. 48 (5), pp. 541-552. Date of Electronic Publication: 2023 Aug 02.
Typ publikacji:
Journal Article
MeSH Terms:
Models, Biological*
Antibodies, Monoclonal*/pharmacokinetics
Humans ; Animals ; Biological Availability ; Administration, Intravenous ; Haplorhini ; Pharmacokinetics
Czasopismo naukowe
Szczegóły
Tytuł:
Control analysis in the identification of key enzymes driving metabolic adaptations: Towards drug target discovery.
Autorzy:
de Atauri P; Department of Biochemistry and Molecular Biomedicine & Institute of Biomedicine of Universitat de Barcelona, Faculty of Biology, Universitat de Barcelona, Barcelona, 08028, Spain; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Instituto de Salud Carlos III (ISCIII), Madrid, 28020, Spain. Electronic address: pde_.
Foguet C; British Heart Foundation Cardiovascular Epidemiology Unit and Victor Phillip Dahdaleh Heart and Lung Research Institute, University of Cambridge, Cambridge, CB2 0BD, United Kingdom.
Cascante M; Department of Biochemistry and Molecular Biomedicine & Institute of Biomedicine of Universitat de Barcelona, Faculty of Biology, Universitat de Barcelona, Barcelona, 08028, Spain; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Instituto de Salud Carlos III (ISCIII), Madrid, 28020, Spain. Electronic address: .
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Źródło:
Bio Systems [Biosystems] 2023 Sep; Vol. 231, pp. 104984. Date of Electronic Publication: 2023 Jul 26.
Typ publikacji:
Journal Article
MeSH Terms:
Models, Biological*
Metabolic Networks and Pathways*/genetics
Kinetics ; Drug Discovery ; Enzymes/genetics ; Enzymes/metabolism
Czasopismo naukowe
Szczegóły
Wyświetlanie 1-20 z 175888

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