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Wyszukujesz frazę ""Models, Biological"" wg kryterium: Temat


Tytuł :
A General Biphasic Bodyweight Model for Scaling Basal Metabolic Rate, Glomerular Filtration Rate, and Drug Clearance from Birth to Adulthood.
Autorzy :
Hu TM; Department of Pharmacy, School of Pharmaceutical Sciences, National Yang Ming Chiao Tung University, Taipei, 112, Taiwan. .
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Źródło :
The AAPS journal [AAPS J] 2022 May 10; Vol. 24 (3), pp. 67. Date of Electronic Publication: 2022 May 10.
Typ publikacji :
Journal Article
MeSH Terms :
Basal Metabolism*
Models, Biological*
Adolescent ; Adult ; Body Weight ; Child ; Child, Preschool ; Drug Elimination Routes ; Female ; Glomerular Filtration Rate ; Humans ; Infant ; Infant, Newborn ; Male ; Metabolic Clearance Rate ; Young Adult
Czasopismo naukowe
Tytuł :
Translational PK-PD for targeted protein degradation.
Autorzy :
Bartlett DW; Pharmacokinetics, Dynamics, & Metabolism, Pfizer Worldwide Research, Development and Medical, Pfizer Inc, San Diego, CA, USA. .
Gilbert AM; Discovery Sciences, Pfizer Worldwide Research, Development and Medical, Pfizer Inc, Groton, CT, USA.
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Źródło :
Chemical Society reviews [Chem Soc Rev] 2022 May 10; Vol. 51 (9), pp. 3477-3486. Date of Electronic Publication: 2022 May 10.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Models, Biological*
Proteolysis
Czasopismo naukowe
Tytuł :
On the global attractivity for a reaction-diffusion malaria model with incubation period in the vector population.
Autorzy :
Zhang R; Department of Mathematics, Nanjing University of Aeronautics and Astronautics, Nanjing, 211106, People's Republic of China.
Wang J; School of Mathematical Science, Heilongjiang University, Harbin, 150080, People's Republic of China. .
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Źródło :
Journal of mathematical biology [J Math Biol] 2022 May 09; Vol. 84 (6), pp. 53. Date of Electronic Publication: 2022 May 09.
Typ publikacji :
Journal Article
MeSH Terms :
Malaria*
Models, Biological*
Animals ; Basic Reproduction Number ; Computer Simulation ; Infectious Disease Incubation Period ; Mosquito Vectors
Czasopismo naukowe
Tytuł :
Stochastic dynamics of an SIS epidemic on networks.
Autorzy :
Jing X; School of Mathematical Sciences, Shanxi University, Taiyuan, 030006, Shanxi, China.
Liu G; School of Mathematical Sciences, Shanxi University, Taiyuan, 030006, Shanxi, China. .
Jin Z; Complex Systems Research Center, Shanxi University, Taiyuan, 030006, Shanxi, China.; Shanxi Key Laboratory of Mathematical Techniques and Big Data Analysis on Disease Control and Prevention, Shanxi University, Taiyuan, 030006, Shanxi, China.
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Źródło :
Journal of mathematical biology [J Math Biol] 2022 May 05; Vol. 84 (6), pp. 50. Date of Electronic Publication: 2022 May 05.
Typ publikacji :
Journal Article
MeSH Terms :
Epidemics*
Models, Biological*
Computer Simulation ; Epidemiological Models ; Humans ; Stochastic Processes
Czasopismo naukowe
Tytuł :
Prediction of In Vivo Pharmacokinetic Parameters and Time-Exposure Curves in Rats Using Machine Learning from the Chemical Structure.
Autorzy :
Obrezanova O; Imaging and Data Analytics, Clinical Pharmacology & Safety Sciences, R&D, AstraZeneca, Cambridge CB4 0FZ, U.K.
Martinsson A; Imaging and Data Analytics, Clinical Pharmacology & Safety Sciences, R&D, AstraZeneca, Gothenburg SE-43183, Sweden.
Whitehead T; Intellegens Ltd., Eagle Labs, Cambridge CB4 3AZ, U.K.
Mahmoud S; Optibrium Ltd., Cambridge Innovation Park, Cambridge CB25 9PB, U.K.
Bender A; Imaging and Data Analytics, Clinical Pharmacology & Safety Sciences, R&D, AstraZeneca, Cambridge CB4 0FZ, U.K.; Department of Chemistry, Centre for Molecular Informatics, University of Cambridge, Cambridge CB2 1EW, U.K.
Miljković F; Imaging and Data Analytics, Clinical Pharmacology & Safety Sciences, R&D, AstraZeneca, Gothenburg SE-43183, Sweden.
Grabowski P; Imaging and Data Analytics, Clinical Pharmacology & Safety Sciences, R&D, AstraZeneca, Cambridge CB4 0FZ, U.K.
Irwin B; Optibrium Ltd., Cambridge Innovation Park, Cambridge CB25 9PB, U.K.
Oprisiu I; Imaging and Data Analytics, Clinical Pharmacology & Safety Sciences, R&D, AstraZeneca, Gothenburg SE-43183, Sweden.
Conduit G; Intellegens Ltd., Eagle Labs, Cambridge CB4 3AZ, U.K.
Segall M; Optibrium Ltd., Cambridge Innovation Park, Cambridge CB25 9PB, U.K.
Smith GF; Imaging and Data Analytics, Clinical Pharmacology & Safety Sciences, R&D, AstraZeneca, Cambridge CB4 0FZ, U.K.
Williamson B; Drug Metabolism and Pharmacokinetics, Research and Early Development, Oncology R&D, AstraZeneca, Cambridge CB10 1XL, U.K.
Winiwarter S; Drug Metabolism and Pharmacokinetics, Research and Early Development, Cardiovascular, Renal and Metabolism (CVRM), Biopharmaceutical R&D, AstraZeneca, Gothenburg SE-43183, Sweden.
Greene N; Imaging and Data Analytics, Clinical Pharmacology & Safety Sciences, R&D, AstraZeneca, Waltham, Massachusetts 02451, United States.
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Źródło :
Molecular pharmaceutics [Mol Pharm] 2022 May 02; Vol. 19 (5), pp. 1488-1504. Date of Electronic Publication: 2022 Apr 12.
Typ publikacji :
Journal Article
MeSH Terms :
Machine Learning*
Models, Biological*
Animals ; Biological Availability ; Drug Discovery ; Metabolic Clearance Rate ; Pharmaceutical Preparations ; Pharmacokinetics ; Rats
Czasopismo naukowe
Tytuł :
Modelling the thermal inactivation of spores from different phylogenetic groups of Bacillus cereus.
Autorzy :
Le Marc Y; Adria Food Technology Institute, UMT ACTIA 19.03 ALTER'iX, ZA Creac'h Gwen, F-29196, Quimper, France. Electronic address: .
Postollec F; Adria Food Technology Institute, UMT ACTIA 19.03 ALTER'iX, ZA Creac'h Gwen, F-29196, Quimper, France.
Huchet V; Adria Food Technology Institute, UMT ACTIA 19.03 ALTER'iX, ZA Creac'h Gwen, F-29196, Quimper, France.
Ellouze M; Nestlé Research Center, Lausanne, Switzerland.
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Źródło :
International journal of food microbiology [Int J Food Microbiol] 2022 May 02; Vol. 368, pp. 109607. Date of Electronic Publication: 2022 Mar 03.
Typ publikacji :
Journal Article
MeSH Terms :
Bacillus cereus*/physiology
Microbial Viability*
Models, Biological*
Spores, Bacterial*
Computer Simulation ; Hot Temperature ; Phylogeny
Czasopismo naukowe
Tytuł :
EMG optimization in OpenSim: A model for estimating lower back kinetics in gait.
Autorzy :
Banks JJ; University of Massachusetts Amherst, Department of Kinesiology, 110 Totman Building, 30 Eastman Lane, Amherst, MA 01003, United States; Beth Israel Deaconess Medical Center, Center for Advanced Orthopaedic Studies, 330 Brookline Avenue, RN 115, Boston, MA 02215, United States; Harvard Medical School, Department of Orthopaedic Surgery, Boston, MA 02115, United States. Electronic address: .
Umberger BR; University of Michigan, School of Kinesiology, 830 North University Avenue, Ann Arbor, MI 48109, United States. Electronic address: .
Caldwell GE; University of Massachusetts Amherst, Department of Kinesiology, 110 Totman Building, 30 Eastman Lane, Amherst, MA 01003, United States. Electronic address: .
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Źródło :
Medical engineering & physics [Med Eng Phys] 2022 May; Vol. 103, pp. 103790. Date of Electronic Publication: 2022 Mar 18.
Typ publikacji :
Journal Article
MeSH Terms :
Models, Biological*
Muscle, Skeletal*/physiology
Gait/physiology ; Humans ; Kinetics ; Lumbar Vertebrae/physiology
Czasopismo naukowe
Tytuł :
PBK modelling of topical application and characterisation of the uncertainty of C max estimate: A case study approach.
Autorzy :
Li H; Unilever Safety and Environmental Assurance Centre, Colworth Science Park, Sharnbrook, Bedfordshire MK44 1LQ, UK. Electronic address: .
Reynolds J; Unilever Safety and Environmental Assurance Centre, Colworth Science Park, Sharnbrook, Bedfordshire MK44 1LQ, UK.
Sorrell I; Unilever Safety and Environmental Assurance Centre, Colworth Science Park, Sharnbrook, Bedfordshire MK44 1LQ, UK.
Sheffield D; Unilever Safety and Environmental Assurance Centre, Colworth Science Park, Sharnbrook, Bedfordshire MK44 1LQ, UK.
Pendlington R; Unilever Safety and Environmental Assurance Centre, Colworth Science Park, Sharnbrook, Bedfordshire MK44 1LQ, UK.
Cubberley R; Unilever Safety and Environmental Assurance Centre, Colworth Science Park, Sharnbrook, Bedfordshire MK44 1LQ, UK.
Nicol B; Unilever Safety and Environmental Assurance Centre, Colworth Science Park, Sharnbrook, Bedfordshire MK44 1LQ, UK.
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Źródło :
Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 2022 May 01; Vol. 442, pp. 115992. Date of Electronic Publication: 2022 Mar 25.
Typ publikacji :
Journal Article
MeSH Terms :
Liver*
Models, Biological*
Bayes Theorem ; Humans ; Kinetics ; Risk Assessment/methods ; Uncertainty
Czasopismo naukowe
Tytuł :
Lower-limb muscle function in healthy young and older adults across a range of walking speeds.
Autorzy :
Lim YP; Department of Mechanical Engineering, University of Melbourne, Parkville, Victoria 3010, Australia.
Lin YC; Department of Mechanical Engineering, University of Melbourne, Parkville, Victoria 3010, Australia.
Pandy MG; Department of Mechanical Engineering, University of Melbourne, Parkville, Victoria 3010, Australia. Electronic address: .
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Źródło :
Gait & posture [Gait Posture] 2022 May; Vol. 94, pp. 124-130. Date of Electronic Publication: 2022 Mar 08.
Typ publikacji :
Journal Article
MeSH Terms :
Models, Biological*
Walking Speed*
Aged ; Biomechanical Phenomena ; Gait/physiology ; Humans ; Muscle, Skeletal/physiology ; Walking/physiology
Czasopismo naukowe
Tytuł :
Predicting Regional Respiratory Tissue and Systemic Concentrations of Orally Inhaled Drugs through a Novel PBPK Model.
Autorzy :
Ladumor MK; Department of Pharmaceutics, School of Pharmacy, University of Washington, Seattle, Washington.
Unadkat JD; Department of Pharmaceutics, School of Pharmacy, University of Washington, Seattle, Washington .
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Źródło :
Drug metabolism and disposition: the biological fate of chemicals [Drug Metab Dispos] 2022 May; Vol. 50 (5), pp. 519-528. Date of Electronic Publication: 2022 Mar 04.
Typ publikacji :
Journal Article
MeSH Terms :
Lung*
Models, Biological*
Administration, Inhalation ; Computer Simulation ; Humans ; Tissue Distribution
Czasopismo naukowe
Tytuł :
A myth of the well-stirred model: Is the well-stirred model good for high clearance drugs?
Autorzy :
Dong J; Department of Pharmaceutics & Medicinal Chemistry, Thomas J. Long School of Pharmacy, University of the Pacific, 751 Brookside Rd B110, Stockton, CA 95211, United States.
Park MS; Department of Pharmaceutics & Medicinal Chemistry, Thomas J. Long School of Pharmacy, University of the Pacific, 751 Brookside Rd B110, Stockton, CA 95211, United States. Electronic address: .
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Źródło :
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences [Eur J Pharm Sci] 2022 May 01; Vol. 172, pp. 106134. Date of Electronic Publication: 2022 Jan 25.
Typ publikacji :
Letter
MeSH Terms :
Liver*/metabolism
Models, Biological*
Drug Interactions ; Kinetics ; Lidocaine/metabolism ; Pharmacokinetics
Opinia redakcyjna
Tytuł :
Sensitivity of the stress field of the proximal femur predicted by CT-based FE analysis to modeling uncertainties.
Autorzy :
Youssefian S; Department of Civil and Systems Engineering, The Johns Hopkins University, Baltimore, Maryland, USA.
Bressner JA; Department of Orthopaedic Surgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Osanov M; Department of Civil and Systems Engineering, The Johns Hopkins University, Baltimore, Maryland, USA.
Guest JK; Department of Civil and Systems Engineering, The Johns Hopkins University, Baltimore, Maryland, USA.
Zbijewski WB; Department of Biomedical Engineering, The Johns Hopkins University, Baltimore, Maryland, USA.
Levin AS; Department of Orthopaedic Surgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
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Źródło :
Journal of orthopaedic research : official publication of the Orthopaedic Research Society [J Orthop Res] 2022 May; Vol. 40 (5), pp. 1163-1173. Date of Electronic Publication: 2021 Jul 13.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Femur*/diagnostic imaging
Models, Biological*
Bone Density ; Elasticity ; Finite Element Analysis ; Humans ; Stress, Mechanical ; Tomography, X-Ray Computed/methods
Czasopismo naukowe
Tytuł :
Physiologically-Based Pharmacokinetic Modeling to Support Determination of Bioequivalence for Dermatological Drug Products: Scientific and Regulatory Considerations.
Autorzy :
Tsakalozou E; Division of Quantitative Methods and Modeling (DQMM), Office of Research and Standards (ORS), Office of Generic Drugs (OGD), Center for Drug Evaluation and Research (CDER), US Food and Drug Administration (FDA), Silver Spring, Maryland, USA.
Alam K; Division of Quantitative Methods and Modeling (DQMM), Office of Research and Standards (ORS), Office of Generic Drugs (OGD), Center for Drug Evaluation and Research (CDER), US Food and Drug Administration (FDA), Silver Spring, Maryland, USA.
Babiskin A; Division of Quantitative Methods and Modeling (DQMM), Office of Research and Standards (ORS), Office of Generic Drugs (OGD), Center for Drug Evaluation and Research (CDER), US Food and Drug Administration (FDA), Silver Spring, Maryland, USA.
Zhao L; Division of Quantitative Methods and Modeling (DQMM), Office of Research and Standards (ORS), Office of Generic Drugs (OGD), Center for Drug Evaluation and Research (CDER), US Food and Drug Administration (FDA), Silver Spring, Maryland, USA.
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Źródło :
Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2022 May; Vol. 111 (5), pp. 1036-1049. Date of Electronic Publication: 2021 Jul 29.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Models, Biological*
Biological Availability ; Computer Simulation ; Humans ; Pharmaceutical Preparations ; Therapeutic Equivalency
Czasopismo naukowe
Tytuł :
Can In Vitro-In Vivo Extrapolation Be Successful? Recognizing the Incorrect Clearance Assumptions.
Autorzy :
Benet LZ; Department of Bioengineering and Therapeutic Sciences, Schools of Pharmacy and Medicine, University of California, San Francisco, California, USA.
Sodhi JK; Department of Bioengineering and Therapeutic Sciences, Schools of Pharmacy and Medicine, University of California, San Francisco, California, USA.
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Źródło :
Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2022 May; Vol. 111 (5), pp. 1022-1035. Date of Electronic Publication: 2021 Dec 08.
Typ publikacji :
Journal Article; Review; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms :
Hepatocytes*/metabolism
Models, Biological*
Humans ; Kinetics ; Liver/metabolism ; Metabolic Clearance Rate
Czasopismo naukowe
Tytuł :
Enzyme-constrained models predict the dynamics of Saccharomyces cerevisiae growth in continuous, batch and fed-batch bioreactors.
Autorzy :
Moreno-Paz S; Laboratory of Systems and Synthetic Biology, Wageningen University & Research, Wageningen, The Netherlands.
Schmitz J; DSM Biotechnology Center, DSM, Delft, The Netherlands.
Martins Dos Santos VAP; Laboratory of Systems and Synthetic Biology, Wageningen University & Research, Wageningen, The Netherlands.; Laboratory of Bioprocess Engineering, Wageningen University & Research, Wageningen, The Netherlands.; Lifeglimmer GmbH, Berlin, Germany.
Suarez-Diez M; Laboratory of Systems and Synthetic Biology, Wageningen University & Research, Wageningen, The Netherlands.
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Źródło :
Microbial biotechnology [Microb Biotechnol] 2022 May; Vol. 15 (5), pp. 1434-1445. Date of Electronic Publication: 2022 Jan 20.
Typ publikacji :
Journal Article
MeSH Terms :
Models, Biological*
Saccharomyces cerevisiae*/genetics
Saccharomyces cerevisiae*/metabolism
Bioreactors ; Carbon/metabolism
Czasopismo naukowe
Tytuł :
Traveling waves of an FKPP-type model for self-organized growth.
Autorzy :
Kreten F; Institut für Angewandte Mathematik, Rheinische Friedrich-Wilhelms-Universität, Endenicher Allee 60, 53129, Bonn, Germany. .
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Źródło :
Journal of mathematical biology [J Math Biol] 2022 Apr 28; Vol. 84 (6), pp. 42. Date of Electronic Publication: 2022 Apr 28.
Typ publikacji :
Journal Article
MeSH Terms :
Models, Biological*
Computer Simulation ; Diffusion
Czasopismo naukowe
Tytuł :
Limited Mechanistic Link Between the Monod Equation and Methanogen Growth: a Perspective from Metabolic Modeling.
Autorzy :
Jin Q; Geobiology Group, University of Oregongrid.170202.6, Eugene, Oregon, USA.
Wu Q; Geobiology Group, University of Oregongrid.170202.6, Eugene, Oregon, USA.
Shapiro BM; Geobiology Group, University of Oregongrid.170202.6, Eugene, Oregon, USA.
McKernan SE; Geobiology Group, University of Oregongrid.170202.6, Eugene, Oregon, USA.
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Źródło :
Microbiology spectrum [Microbiol Spectr] 2022 Apr 27; Vol. 10 (2), pp. e0225921. Date of Electronic Publication: 2022 Mar 03.
Typ publikacji :
Journal Article
MeSH Terms :
Metabolic Networks and Pathways*
Models, Biological*
Kinetics
Czasopismo naukowe
Tytuł :
Use of Physiologically Based Kinetic Modeling-Facilitated Reverse Dosimetry to Predict In Vivo Acute Toxicity of Tetrodotoxin in Rodents.
Autorzy :
Noorlander A; Division of Toxicology, Wageningen University, 6708 WE Wageningen, The Netherlands.
Zhang M; Division of Toxicology, Wageningen University, 6708 WE Wageningen, The Netherlands.
van Ravenzwaay B; Division of Toxicology, Wageningen University, 6708 WE Wageningen, The Netherlands.; Experimental Toxicology and Ecology, BASF SE, Ludwigshafen 67056, Germany.
Rietjens IMCM; Division of Toxicology, Wageningen University, 6708 WE Wageningen, The Netherlands.
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Źródło :
Toxicological sciences : an official journal of the Society of Toxicology [Toxicol Sci] 2022 Apr 26; Vol. 187 (1), pp. 127-138.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Models, Biological*
Rodentia*
Animals ; Dose-Response Relationship, Drug ; Kinetics ; Mice ; Rats ; Tetrodotoxin/toxicity
Czasopismo naukowe
Tytuł :
The effects of random and seasonal environmental fluctuations on optimal harvesting and stocking.
Autorzy :
Hening A; Department of Mathematics, Texas A &M University, Mailstop 3368, College Station, TX, 77843-3368, USA. .
Tran KQ; Department of Mathematics and Statistics, The State University of New York in Korea, 119 SongdoMoonhwa-Ro, Yeonsu-Gu, Incheon, 21985, Korea.
Ungureanu SC; Department of Economics City, University of London, Northampton Square, London, EC1V 0HB, UK.
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Źródło :
Journal of mathematical biology [J Math Biol] 2022 Apr 25; Vol. 84 (6), pp. 41. Date of Electronic Publication: 2022 Apr 25.
Typ publikacji :
Journal Article
MeSH Terms :
Models, Biological*
Population Dynamics ; Seasons ; Stochastic Processes
Czasopismo naukowe
Tytuł :
Editorial: Living machines: from biological models to soft machines.
Autorzy :
Tauber F; Cluster of Excellence livMatS@ FIT-Freiburg Center for Interactive Materials and Bioinspired Technologies, University of Freiburg, Germany.; Plant Biomechanics Group & Botanic Garden, University of Freiburg, Germany.
Vouloutsi V; Autonomous Robotics Research Centre, Technology Innovation Institute, Abu Dhabi, United Arab Emirates.
Mura A; Institute for Bioengineering of Catalonia, Barcelona, Spain.
Speck T; Cluster of Excellence livMatS@ FIT-Freiburg Center for Interactive Materials and Bioinspired Technologies, University of Freiburg, Germany.; Plant Biomechanics Group & Botanic Garden, University of Freiburg, Germany.
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Źródło :
Bioinspiration & biomimetics [Bioinspir Biomim] 2022 Apr 25; Vol. 17 (3). Date of Electronic Publication: 2022 Apr 25.
Typ publikacji :
Editorial
MeSH Terms :
Models, Biological*
Biomimetics
Opinia redakcyjna

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