Temat: "Models, Biological" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Transcription factor competition facilitates self-sustained oscillations in single gene genetic circuits.
Autorzy:: Landman J; Physics & Physical Chemistry of Foods, Wageningen University & Research, Wageningen, the Netherlands.
Verduyn Lunel SM; Mathematisch Instituut, Utrecht University, Utrecht, the Netherlands.
Kegel WK; Van 't Hoff Laboratory for Physical & Colloid Chemistry, Utrecht University, Utrecht, the Netherlands.; Pokaż więcej
Źródło:: PLoS computational biology [PLoS Comput Biol] 2023 Sep 29; Vol. 19 (9), pp. e1011525. Date of Electronic Publication: 2023 Sep 29 (Print Publication: 2023).
Typ publikacji:: Journal Article
MeSH Terms:: Transcription Factors*/genetics
Gene Expression Regulation*/genetics
Gene Regulatory Networks/genetics ; Feedback ; Models, Biological ; Feedback, Physiological ; Transcription, Genetic

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Skocz do pozycji: 2.

Tytuł:: Osthole Inhibits Expression of Genes Associated with Toll-like Receptor 2 Signaling Pathway in an Organotypic 3D Skin Model of Human Epidermis with Atopic Dermatitis.
Autorzy:: Kordulewska NK; Department of Biochemistry, Faculty of Biology and Biotechnology, University of Warmia and Mazury in Olsztyn, 10-719 Olsztyn, Poland.
Topa J; Laboratory of Translational Oncology, Intercollegiate Faculty of Biotechnology, Medical University of Gdańsk, 80-211 Gdańsk, Poland.
Stryiński R; Department of Biochemistry, Faculty of Biology and Biotechnology, University of Warmia and Mazury in Olsztyn, 10-719 Olsztyn, Poland.
Jarmołowska B; Department of Biochemistry, Faculty of Biology and Biotechnology, University of Warmia and Mazury in Olsztyn, 10-719 Olsztyn, Poland.; Pokaż więcej
Źródło:: Cells [Cells] 2021 Dec 28; Vol. 11 (1). Date of Electronic Publication: 2021 Dec 28.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Gene Expression Regulation*/drug effects
Models, Biological*
Signal Transduction*/genetics
Coumarins/*pharmacology
Dermatitis, Atopic/*genetics
Dermatitis, Atopic/*pathology
Epidermis/*pathology
Toll-Like Receptor 2/*metabolism
Cells, Cultured ; Chemokines/metabolism ; Cyclooxygenase 2/metabolism ; Histamine/pharmacology ; Humans ; Inflammation/pathology ; Lipopolysaccharides/pharmacology ; Male ; Tight Junctions/drug effects ; Tight Junctions/metabolism

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Skocz do pozycji: 3.

Tytuł:: A spatio-temporal model to reveal oscillator phenotypes in molecular clocks: Parameter estimation elucidates circadian gene transcription dynamics in single-cells.
Autorzy:: Unosson M; Department of Statistics, University of Warwick, Coventry, United Kingdom.
Brancaccio M; UK Dementia Research Institute at Imperial College London, Department of Brain Sciences, Faculty of Medicine, London, United Kingdom.
Hastings M; MRC Laboratory of Molecular Biology, Division of Neurobiology, Cambridge, United Kingdom.
Johansen AM; Department of Statistics, University of Warwick, Coventry, United Kingdom.
Finkenstädt B; Department of Statistics, University of Warwick, Coventry, United Kingdom.; The Zeeman Institute for Systems Biology & Infectious Disease Epidemiology Research, University of Warwick, Coventry, United Kingdom.; Pokaż więcej
Źródło:: PLoS computational biology [PLoS Comput Biol] 2021 Dec 17; Vol. 17 (12), pp. e1009698. Date of Electronic Publication: 2021 Dec 17 (Print Publication: 2021).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Circadian Rhythm Signaling Peptides and Proteins*/genetics
Circadian Rhythm Signaling Peptides and Proteins*/metabolism
Models, Biological*
Circadian Clocks/*genetics
Gene Expression Regulation/*genetics
Transcription, Genetic/*genetics
Animals ; Cryptochromes/genetics ; Cryptochromes/metabolism ; Mice ; Phenotype ; Single-Cell Analysis ; Stochastic Processes ; Suprachiasmatic Nucleus/cytology ; Suprachiasmatic Nucleus/metabolism

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Skocz do pozycji: 4.

Tytuł:: Biological features between miRNAs and their targets are unveiled from deep learning models.
Autorzy:: Gu T; Bioinformatics, Interdisciplinary Center for Biotechnology Research, University of Florida, Gainesville, FL, USA. .; Division of Quantitative Sciences, University of Florida Health Cancer Center, University of Florida, 2033 Mowry Road, Gainesville, FL, 32610, USA. .
Xie M; University of Florida Health Cancer Center, University of Florida, Gainesville, FL, USA.; Genetics Institute, University of Florida, Gainesville, FL, USA.; Department of Biochemistry and Molecular Biology, University of Florida, Gainesville, FL, 32610, USA.
Barbazuk WB; Bioinformatics, Interdisciplinary Center for Biotechnology Research, University of Florida, Gainesville, FL, USA.; Genetics Institute, University of Florida, Gainesville, FL, USA.; Department of Biology, University of Florida, Gainesville, FL, USA.
Lee JH; Division of Quantitative Sciences, University of Florida Health Cancer Center, University of Florida, 2033 Mowry Road, Gainesville, FL, 32610, USA. .; Department of Biostatistics, University of Florida, Gainesville, FL, USA. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2021 Dec 10; Vol. 11 (1), pp. 23825. Date of Electronic Publication: 2021 Dec 10.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Deep Learning*
Gene Expression Regulation*
Models, Biological*
RNA Interference*
Computational Biology/*methods
RNA, Messenger/*genetics
Algorithms ; Base Pairing ; Databases, Nucleic Acid ; Gene Regulatory Networks ; Humans ; MicroRNAs/genetics ; Mutagenesis

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Skocz do pozycji: 5.

Tytuł:: A Distinctive NAFLD Signature in Adipose Tissue from Women with Severe Obesity.
Autorzy:: Osorio-Conles Ó; Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Instituto de Salud Carlos III (ISCIII), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Rosselló Street 149, 08036 Barcelona, Spain.
Vega-Beyhart A; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain.
Ibarzabal A; Gastrointestinal Surgery Department, Hospital Clínic de Barcelona, 08036 Barcelona, Spain.
Balibrea JM; Gastrointestinal Surgery Department, Hospital Clínic de Barcelona, 08036 Barcelona, Spain.
Graupera I; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Liver Unit, Hospital Clínic de Barcelona, 08036 Barcelona, Spain.
Rimola J; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Liver Unit, Hospital Clínic de Barcelona, 08036 Barcelona, Spain.
Vidal J; Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Instituto de Salud Carlos III (ISCIII), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Rosselló Street 149, 08036 Barcelona, Spain.; Obesity Unit, Endocrinology and Nutrition Department, Hospital Clínic de Barcelona, 08036 Barcelona, Spain.
de Hollanda A; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain.; Obesity Unit, Endocrinology and Nutrition Department, Hospital Clínic de Barcelona, 08036 Barcelona, Spain.; Centro de Investigación Biomédica en Red Fisiopatologia de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III (ISCIII), 28029 Madrid, Spain.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 Sep 29; Vol. 22 (19). Date of Electronic Publication: 2021 Sep 29.
Typ publikacji:: Clinical Trial; Comparative Study; Journal Article
MeSH Terms:: Gene Expression Regulation*
Models, Biological*
Adipokines/*biosynthesis
Intra-Abdominal Fat/*metabolism
Non-alcoholic Fatty Liver Disease/*metabolism
Obesity, Morbid/*metabolism
Subcutaneous Fat/*metabolism
Adult ; Female ; Humans ; Intra-Abdominal Fat/pathology ; Middle Aged ; Non-alcoholic Fatty Liver Disease/pathology ; Obesity, Morbid/pathology ; Real-Time Polymerase Chain Reaction ; Reverse Transcriptase Polymerase Chain Reaction ; Subcutaneous Fat/pathology

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Skocz do pozycji: 6.

Tytuł:: A Modular Mathematical Model of Exercise-Induced Changes in Metabolism, Signaling, and Gene Expression in Human Skeletal Muscle.
Autorzy:: Akberdin IR; Department of Computational Biology, Scientific Center for Information Technologies and Artificial Intelligence, Sirius University of Science and Technology, 354340 Sochi, Russia.; BIOSOFT.RU, LLC, 630090 Novosibirsk, Russia.; Department of Natural Sciences, Novosibirsk State University, 630090 Novosibirsk, Russia.; Federal Research Center Institute of Cytology and Genetics SB RAS, 630090 Novosibirsk, Russia.
Kiselev IN; Department of Computational Biology, Scientific Center for Information Technologies and Artificial Intelligence, Sirius University of Science and Technology, 354340 Sochi, Russia.; BIOSOFT.RU, LLC, 630090 Novosibirsk, Russia.; Laboratory of Bioinformatics, Federal Research Center for Information and Computational Technologies, 633010 Novosibirsk, Russia.
Pintus SS; Department of Computational Biology, Scientific Center for Information Technologies and Artificial Intelligence, Sirius University of Science and Technology, 354340 Sochi, Russia.; BIOSOFT.RU, LLC, 630090 Novosibirsk, Russia.; Laboratory of Bioinformatics, Federal Research Center for Information and Computational Technologies, 633010 Novosibirsk, Russia.
Sharipov RN; Department of Computational Biology, Scientific Center for Information Technologies and Artificial Intelligence, Sirius University of Science and Technology, 354340 Sochi, Russia.; BIOSOFT.RU, LLC, 630090 Novosibirsk, Russia.; Department of Natural Sciences, Novosibirsk State University, 630090 Novosibirsk, Russia.; Laboratory of Bioinformatics, Federal Research Center for Information and Computational Technologies, 633010 Novosibirsk, Russia.
Vertyshev AY; JSC 'Sites-Tsentr', 123182 Moscow, Russia.
Vinogradova OL; Institute of Biomedical Problems of the Russian Academy of Sciences, 123007 Moscow, Russia.
Popov DV; Institute of Biomedical Problems of the Russian Academy of Sciences, 123007 Moscow, Russia.
Kolpakov FA; Department of Computational Biology, Scientific Center for Information Technologies and Artificial Intelligence, Sirius University of Science and Technology, 354340 Sochi, Russia.; BIOSOFT.RU, LLC, 630090 Novosibirsk, Russia.; Laboratory of Bioinformatics, Federal Research Center for Information and Computational Technologies, 633010 Novosibirsk, Russia.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 Sep 26; Vol. 22 (19). Date of Electronic Publication: 2021 Sep 26.
Typ publikacji:: Journal Article
MeSH Terms:: Calcium Signaling*
Energy Metabolism*
Exercise*
Gene Expression Regulation*
Models, Biological*
Muscle, Skeletal/*metabolism
Humans

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Skocz do pozycji: 7.

Tytuł:: B6-Dct-H2BGFP bitransgenic mice: A standardized mouse model for in vivo characterization of melanocyte development and stem cell differentiation.
Autorzy:: Tandukar B; Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, MD, USA.
Kalapurakal E; Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, MD, USA.
Hornyak TJ; Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, MD, USA.; Department of Dermatology, University of Maryland School of Medicine, Baltimore, MD, USA.; Research & Development Service, VA Maryland Health Care System, Baltimore, MD, USA.; Pokaż więcej
Źródło:: Pigment cell & melanoma research [Pigment Cell Melanoma Res] 2021 Sep; Vol. 34 (5), pp. 905-917. Date of Electronic Publication: 2021 May 18.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:: Cell Differentiation*
Gene Expression Regulation*
Models, Biological*
Melanocytes/*metabolism
Membrane Glycoproteins/*biosynthesis
Microphthalmia-Associated Transcription Factor/*biosynthesis
Oxidoreductases/*biosynthesis
Stem Cells/*metabolism
Animals ; Membrane Glycoproteins/genetics ; Mice ; Mice, Transgenic ; Microphthalmia-Associated Transcription Factor/genetics ; Oxidoreductases/genetics

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Skocz do pozycji: 8.

Tytuł:: Identification of genes associated with altered gene expression and m6A profiles during hypoxia using tensor decomposition based unsupervised feature extraction.
Autorzy:: Roy SS; School of Computer Science and Engineering, Vellore Institute of Technology, Vellore, India.
Taguchi YH; Department of Physics, Chuo University, Tokyo, 112-8551, Japan. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2021 Apr 26; Vol. 11 (1), pp. 8909. Date of Electronic Publication: 2021 Apr 26.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Algorithms*
Databases, Nucleic Acid*
Gene Expression Profiling*
Gene Expression Regulation*
Hypoxia*/genetics
Hypoxia*/metabolism
Models, Biological*
Humans

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Skocz do pozycji: 9.

Tytuł:: A transcription-centric model of SNP-age interaction.
Autorzy:: Wang K; Cancer Data Science Laboratory, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America.; Center for Bioinformatics and Computational Biology, University of Maryland, College Park, Maryland, United States of America.
Basu M; Center for Bioinformatics and Computational Biology, University of Maryland, College Park, Maryland, United States of America.; Institute for Genome Sciences, University of Maryland, Baltimore, Maryland, United States of America.
Malin J; Laboratory of Genome Integrity, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America.
Hannenhalli S; Cancer Data Science Laboratory, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America.; Center for Bioinformatics and Computational Biology, University of Maryland, College Park, Maryland, United States of America.; Pokaż więcej
Źródło:: PLoS genetics [PLoS Genet] 2021 Mar 26; Vol. 17 (3), pp. e1009427. Date of Electronic Publication: 2021 Mar 26 (Print Publication: 2021).
Typ publikacji:: Journal Article; Research Support, N.I.H., Intramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:: Gene Expression Regulation*
Models, Biological*
Phenotype*
Polymorphism, Single Nucleotide*
Transcription, Genetic*
Aging/*genetics
Algorithms ; Alleles ; Humans ; Transcription Factors/metabolism

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Skocz do pozycji: 10.

Tytuł:: hiPSC-Derived Epidermal Keratinocytes from Ichthyosis Patients Show Altered Expression of Cornification Markers.
Autorzy:: Lima Cunha D; Department of Biological and Geographical Sciences, University of Huddersfield, Queensgate, Huddersfield HD1 3DH, UK.; Institute of Human Genetics, Medical University of Innsbruck, Peter-Mayr-Str. 1, 6020 Innsbruck, Austria.; Cologne Center for Genomics, University Hospital Cologne, Weyertal 115b, 50931 Cologne, Germany.
Oram A; Department of Biological and Geographical Sciences, University of Huddersfield, Queensgate, Huddersfield HD1 3DH, UK.
Gruber R; Department of Dermatology, Venereology and Allergy, Medical University of Innsbruck, Anichstrasse 35, 6020 Innsbruck, Austria.
Plank R; Department of Biological and Geographical Sciences, University of Huddersfield, Queensgate, Huddersfield HD1 3DH, UK.; Institute of Human Genetics, Medical University of Innsbruck, Peter-Mayr-Str. 1, 6020 Innsbruck, Austria.
Lingenhel A; Institute of Human Genetics, Medical University of Innsbruck, Peter-Mayr-Str. 1, 6020 Innsbruck, Austria.
Gupta MK; Center for Physiology and Pathophysiology, Institute for Neurophysiology, Medical Faculty, University Hospital Cologne, Robert-Koch-Str. 39, 50931 Cologne, Germany.
Altmüller J; Cologne Center for Genomics, University Hospital Cologne, Weyertal 115b, 50931 Cologne, Germany.
Nürnberg P; Cologne Center for Genomics, University Hospital Cologne, Weyertal 115b, 50931 Cologne, Germany.
Schmuth M; Department of Dermatology, Venereology and Allergy, Medical University of Innsbruck, Anichstrasse 35, 6020 Innsbruck, Austria.
Zschocke J; Institute of Human Genetics, Medical University of Innsbruck, Peter-Mayr-Str. 1, 6020 Innsbruck, Austria.
Šarić T; Center for Physiology and Pathophysiology, Institute for Neurophysiology, Medical Faculty, University Hospital Cologne, Robert-Koch-Str. 39, 50931 Cologne, Germany.
Eckl KM; Institute of Human Genetics, Medical University of Innsbruck, Peter-Mayr-Str. 1, 6020 Innsbruck, Austria.; Department of Biology, Edge Hill University, St Helens Road, Ormskirk L39 4QP, UK.
Hennies HC; Department of Biological and Geographical Sciences, University of Huddersfield, Queensgate, Huddersfield HD1 3DH, UK.; Institute of Human Genetics, Medical University of Innsbruck, Peter-Mayr-Str. 1, 6020 Innsbruck, Austria.; Cologne Center for Genomics, University Hospital Cologne, Weyertal 115b, 50931 Cologne, Germany.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 Feb 11; Vol. 22 (4). Date of Electronic Publication: 2021 Feb 11.
Typ publikacji:: Journal Article
MeSH Terms:: Gene Expression Regulation*
Models, Biological*
Ichthyosis/*metabolism
Induced Pluripotent Stem Cells/*metabolism
Keratinocytes/*metabolism
Child ; Child, Preschool ; Female ; Filaggrin Proteins ; Humans ; Ichthyosis/pathology ; Induced Pluripotent Stem Cells/pathology ; Infant ; Keratinocytes/pathology ; Male

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Skocz do pozycji: 11.

Tytuł:: Devil in the details: Mechanistic variations impact information transfer across models of transcriptional cascades.
Autorzy:: Rowland MA; Environmental Laboratory, U.S. Army Engineer Research and Development Center, Vicksburg, MS, United States of America.
Pilkiewicz KR; Environmental Laboratory, U.S. Army Engineer Research and Development Center, Vicksburg, MS, United States of America.
Mayo ML; Environmental Laboratory, U.S. Army Engineer Research and Development Center, Vicksburg, MS, United States of America.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2021 Jan 13; Vol. 16 (1), pp. e0245094. Date of Electronic Publication: 2021 Jan 13 (Print Publication: 2021).
Typ publikacji:: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:: Gene Expression Regulation*
Gene Regulatory Networks*
Models, Biological*
Signal Transduction*
Animals ; Humans ; Kinetics

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Skocz do pozycji: 12.

Tytuł:: Gene expression is stable in a complete CIB1 knockout keratinocyte model.
Autorzy:: Imahorn E; Department of Biomedicine, University of Basel and University Hospital Basel, Basel, Switzerland.
Aushev M; Wellcome Centre for Mitochondrial Research, Institute of Genetic Medicine, Newcastle upon Tyne, UK.
Herms S; Department of Biomedicine, University of Basel and University Hospital Basel, Basel, Switzerland.; Institute of Human Genetics, Division of Genomics, Life & Brain Research Centre, University Hospital of Bonn, Bonn, Germany.
Hoffmann P; Department of Biomedicine, University of Basel and University Hospital Basel, Basel, Switzerland.; Institute of Human Genetics, Division of Genomics, Life & Brain Research Centre, University Hospital of Bonn, Bonn, Germany.; Institute of Neuroscience and Medicine (INM-1), Genomic Imaging, Research Center Juelich, Juelich, Germany.
Cichon S; Department of Biomedicine, University of Basel and University Hospital Basel, Basel, Switzerland.; Institute of Neuroscience and Medicine (INM-1), Genomic Imaging, Research Center Juelich, Juelich, Germany.
Reichelt J; Department of Dermatology, Venereology and Allergology, Medical University Innsbruck, Innsbruck, Austria.
Itin PH; Department of Biomedicine, University of Basel and University Hospital Basel, Basel, Switzerland.; Department of Dermatology, University Hospital Basel, Basel, Switzerland.
Burger B; Department of Biomedicine, University of Basel and University Hospital Basel, Basel, Switzerland. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2020 Sep 11; Vol. 10 (1), pp. 14952. Date of Electronic Publication: 2020 Sep 11.
Typ publikacji:: Journal Article
MeSH Terms:: Epidermodysplasia Verruciformis*/genetics
Epidermodysplasia Verruciformis*/metabolism
Epidermodysplasia Verruciformis*/pathology
Gene Expression Regulation*
Models, Biological*
Calcium-Binding Proteins/*deficiency
Keratinocytes/*metabolism
Calcium-Binding Proteins/metabolism ; Cell Line ; Gene Knockout Techniques ; Humans ; Keratinocytes/pathology

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Skocz do pozycji: 13.

Tytuł:: Contributions to the 'noise floor' in gene expression in a population of dividing cells.
Autorzy:: Jędrak J; Institute of Physical Chemistry, Polish Academy of Sciences, ul. Kasprzaka 44/52, 01-224, Warsaw, Poland. .
Ochab-Marcinek A; Institute of Physical Chemistry, Polish Academy of Sciences, ul. Kasprzaka 44/52, 01-224, Warsaw, Poland.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2020 Aug 11; Vol. 10 (1), pp. 13533. Date of Electronic Publication: 2020 Aug 11.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Cell Division*
Gene Expression Regulation*
Models, Biological*
Protein Biosynthesis*
Proteins/*metabolism
Algorithms ; Cell Cycle ; Cells, Cultured ; Humans ; Proteins/genetics

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Skocz do pozycji: 14.

Tytuł:: Affinity, Specificity, and Cooperativity of DNA Binding by Bacterial Gene Regulatory Proteins.
Autorzy:: Carey J; Chemistry Department, Princeton University, Princeton, NJ 08544, USA.; Laboratory of Structural Biology and Bioinformatics, Institute of Microbiology, Czech Academy of Sciences, 37333 Nové Hrady, South Bohemia, Czech Republic.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2022 Jan 05; Vol. 23 (1). Date of Electronic Publication: 2022 Jan 05.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Bacterial Physiological Phenomena*
Gene Expression Regulation*
Host Microbial Interactions*
Bacterial Proteins/*metabolism
DNA-Binding Proteins/*metabolism
Animals ; DNA/genetics ; DNA/metabolism ; Humans ; Models, Biological ; Protein Binding

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Skocz do pozycji: 15.

Tytuł:: Overexpression of microRNAs miR-25-3p, miR-185-5p and miR-132-3p in Late Onset Fetal Growth Restriction, Validation of Results and Study of the Biochemical Pathways Involved.
Autorzy:: Loscalzo G; Instituto de Investigación Sanitaria La Fe, 46026 Valencia, Spain.; Department of Obstetrics and Gynecology, Hospital Universitario y Politécnico La Fe, 46026 Valencia, Spain.
Scheel J; Department of Systems Biology and Bioinformatics, University Rostock, 18055 Rostock, Germany.
Ibañez-Cabellos JS; EpiDisease S.L, Parc Científic, University of Valencia, 46980 Paterna, Spain.; Consortium Center for Biomedical Network Research on Rare Diseases (CIBERER), Carrer d'Alvaro de Bazan, 10, 46010 Valencia, Spain.
García-Lopez E; EpiDisease S.L, Parc Científic, University of Valencia, 46980 Paterna, Spain.
Gupta S; Department of Systems Biology and Bioinformatics, University Rostock, 18055 Rostock, Germany.
García-Gimenez JL; EpiDisease S.L, Parc Científic, University of Valencia, 46980 Paterna, Spain.; Consortium Center for Biomedical Network Research on Rare Diseases (CIBERER), Carrer d'Alvaro de Bazan, 10, 46010 Valencia, Spain.; Institute of Health Carlos III, Biomedical Research Institute INCLIVA, 46010 Valencia, Spain.; Department of Physiology, School of Medicine and Dentistry, University of Valencia, 46010 Valencia, Spain.
Mena-Mollá S; EpiDisease S.L, Parc Científic, University of Valencia, 46980 Paterna, Spain.; Institute of Health Carlos III, Biomedical Research Institute INCLIVA, 46010 Valencia, Spain.; Department of Physiology, School of Medicine and Dentistry, University of Valencia, 46010 Valencia, Spain.
Perales-Marín A; Instituto de Investigación Sanitaria La Fe, 46026 Valencia, Spain.; Department of Obstetrics and Gynecology, Hospital Universitario y Politécnico La Fe, 46026 Valencia, Spain.; Department of Pediatrics, Obstetrics and Gynecology, School of Medicine and Dentistry, University of Valencia, 46010 Valencia, Spain.
Morales-Roselló J; Instituto de Investigación Sanitaria La Fe, 46026 Valencia, Spain.; Department of Obstetrics and Gynecology, Hospital Universitario y Politécnico La Fe, 46026 Valencia, Spain.; Department of Pediatrics, Obstetrics and Gynecology, School of Medicine and Dentistry, University of Valencia, 46010 Valencia, Spain.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 Dec 28; Vol. 23 (1). Date of Electronic Publication: 2021 Dec 28.
Typ publikacji:: Journal Article
MeSH Terms:: Gene Expression Regulation*
MicroRNAs/*genetics
Signal Transduction/*genetics
Fetal Growth Retardation/genetics ; Gene Expression Profiling ; Gene Ontology ; Gene Regulatory Networks ; Humans ; MicroRNAs/metabolism ; Models, Biological ; Reproducibility of Results

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Skocz do pozycji: 16.

Tytuł:: Anti-inflammatory effects of α-MSH through p-CREB expression in sarcoidosis like granuloma model.
Autorzy:: Zhang C; Section of Pulmonary, Miami VA Health System, Miami, FL, USA.
Chery S; Departments of Medicine University of Miami Miller School of Medicine, Miami, FL, USA.
Lazerson A; Comparative Pathology, University of Miami Miller School of Medicine, Miami, FL, USA.
Altman NH; Comparative Pathology, University of Miami Miller School of Medicine, Miami, FL, USA.
Jackson R; Section of Pulmonary, Miami VA Health System, Miami, FL, USA.; Division of Pulmonary and Critical Care, University of Miami Miller School of Medicine, Miami, FL, USA.
Holt G; Section of Pulmonary, Miami VA Health System, Miami, FL, USA.; Division of Pulmonary and Critical Care, University of Miami Miller School of Medicine, Miami, FL, USA.
Campos M; Section of Pulmonary, Miami VA Health System, Miami, FL, USA.; Division of Pulmonary and Critical Care, University of Miami Miller School of Medicine, Miami, FL, USA.
Schally AV; Polypeptide and Cancer Institute, Veterans Affairs Medical Center, Miami, FL, USA.
Mirsaeidi M; Section of Pulmonary, Miami VA Health System, Miami, FL, USA. .; Division of Pulmonary and Critical Care, University of Miami Miller School of Medicine, Miami, FL, USA. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2020 Apr 29; Vol. 10 (1), pp. 7277. Date of Electronic Publication: 2020 Apr 29.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Granuloma*/metabolism
Granuloma*/microbiology
Granuloma*/pathology
Leukocytes, Mononuclear*/metabolism
Leukocytes, Mononuclear*/microbiology
Leukocytes, Mononuclear*/pathology
Models, Biological*
Sarcoidosis*/metabolism
Sarcoidosis*/microbiology
Sarcoidosis*/pathology
Anti-Inflammatory Agents/*pharmacology
Cyclic AMP Response Element-Binding Protein/*metabolism
Gene Expression Regulation/*drug effects
Mycobacterium Infections, Nontuberculous/*metabolism
Mycobacterium abscessus/*metabolism
alpha-MSH/*pharmacology
Child ; Humans ; Male ; Mycobacterium Infections, Nontuberculous/pathology

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Skocz do pozycji: 17.

Tytuł:: Validation of Reference Genes for Gene Expression Studies by RT-qPCR in HepaRG Cells during Toxicity Testing and Disease Modelling.
Autorzy:: Brzeszczyńska J; University of Edinburgh Hepatology Laboratory, Chancellor's Building, Edinburgh BioQuarter, 49 Little France Crescent, Edinburgh EH16 4SB, UK.; Department of Molecular Biophysics, University of Lodz, 90-236 Lodz, Poland.
Brzeszczyński F; School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, 97 Lisburn Rd, Belfast BT9 7BL, UK.
Samuel K; Scottish National Blood Transfusion Service, Jack Copland Centre, 52 Research Avenue North, Edinburgh EH14 4BE, UK.
Morgan K; University of Edinburgh Hepatology Laboratory, Chancellor's Building, Edinburgh BioQuarter, 49 Little France Crescent, Edinburgh EH16 4SB, UK.
Morley SD; University of Edinburgh Hepatology Laboratory, Chancellor's Building, Edinburgh BioQuarter, 49 Little France Crescent, Edinburgh EH16 4SB, UK.
Plevris JN; University of Edinburgh Hepatology Laboratory, Chancellor's Building, Edinburgh BioQuarter, 49 Little France Crescent, Edinburgh EH16 4SB, UK.
Hayes PC; University of Edinburgh Hepatology Laboratory, Chancellor's Building, Edinburgh BioQuarter, 49 Little France Crescent, Edinburgh EH16 4SB, UK.; Pokaż więcej
Źródło:: Cells [Cells] 2020 Mar 21; Vol. 9 (3). Date of Electronic Publication: 2020 Mar 21.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Validation Study
MeSH Terms:: Gene Expression Regulation*/drug effects
Models, Biological*
Toxicity Tests*
Disease/*genetics
Real-Time Polymerase Chain Reaction/*methods
Real-Time Polymerase Chain Reaction/*standards
Acetaminophen/toxicity ; Adenosine Triphosphate/metabolism ; Cell Line ; Cell Survival/drug effects ; Cell Survival/genetics ; Chlorpromazine/toxicity ; Genes, Essential ; Humans ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Reference Standards ; Transcription, Genetic/drug effects

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Skocz do pozycji: 18.

Tytuł:: Development of Physiologically Responsive Human iPSC-Derived Intestinal Epithelium to Study Barrier Dysfunction in IBD.
Autorzy:: Gleeson JP; Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Estrada HQ; Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Yamashita M; Department of Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Svendsen CN; Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.; Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Targan SR; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Barrett RJ; Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2020 Feb 20; Vol. 21 (4). Date of Electronic Publication: 2020 Feb 20.
Typ publikacji:: Journal Article
MeSH Terms:: Gene Expression Regulation*
Models, Biological*
Colon/*metabolism
Induced Pluripotent Stem Cells/*metabolism
Inflammatory Bowel Diseases/*metabolism
Intestinal Mucosa/*metabolism
Cell Line ; Colon/pathology ; Humans ; Induced Pluripotent Stem Cells/pathology ; Inflammatory Bowel Diseases/pathology ; Intestinal Mucosa/pathology ; Organoids/metabolism ; Organoids/pathology

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Skocz do pozycji: 19.

Tytuł:: A Novel Schizophrenia Diagnostic Model Based on Statistically Significant Changes in Gene Methylation in Specific Brain Regions.
Autorzy:: Zou D; Department of Neurology, The Fifth Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi 530022, China.
Qiu Y; Maternal and Child Health Hospital and Obstetrics and Gynecology Hospital of Guangxi Zhuang Autonomous Region, Nanning, Guangxi 530003, China.
Li R; Department of Neurology, The Fifth Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi 530022, China.
Meng Y; Department of Neurology, The Fifth Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi 530022, China.
Wu Y; Department of Neurology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi 530021, China.; Pokaż więcej
Źródło:: BioMed research international [Biomed Res Int] 2020 Feb 12; Vol. 2020, pp. 8047146. Date of Electronic Publication: 2020 Feb 12 (Print Publication: 2020).
Typ publikacji:: Journal Article
MeSH Terms:: DNA Methylation*
Databases, Nucleic Acid*
Gene Expression Regulation*
MAP Kinase Signaling System*
Models, Biological*
Schizophrenia*/diagnosis
Schizophrenia*/genetics
Schizophrenia*/metabolism
Brain/*metabolism
Humans

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Skocz do pozycji: 20.

Tytuł:: Expression of Selected Connexin and Aquaporin Genes and Real-Time Proliferation of Porcine Endometrial Luminal Epithelial Cells in Primary Culture Model.
Autorzy:: Wojtanowicz-Markiewicz K; Veterinary Centre, Nicolaus Copernicus University in Torun, Torun, Poland.
Kulus M; Veterinary Centre, Nicolaus Copernicus University in Torun, Torun, Poland.
Knap S; Department of Histology and Embryology, Poznan University of Medical Sciences, Poznan, Poland.
Kocherova I; Department of Anatomy, Poznan University of Medical Sciences, Poznan, Poland.
Jankowski M; Department of Anatomy, Poznan University of Medical Sciences, Poznan, Poland.
Stefańska K; Department of Histology and Embryology, Poznan University of Medical Sciences, Poznan, Poland.
Jeseta M; Department of Obstetrics and Gynaecology, University Hospital and Masaryk University, Brno, Czech Republic.
Piotrowska-Kempisty H; Department of Toxicology, Poznan University of Medical Sciences, Poznan, Poland.
Bukowska D; Veterinary Centre, Nicolaus Copernicus University in Torun, Torun, Poland.
Zabel M; Division of Histology and Embryology, Department of Human Morphology and Embryology, Wroclaw Medical University, Wroclaw, Poland.; Division of Anatomy and Histology, University of Zielona Góra, Zielona Góra, Poland.
Mozdziak P; Physiology Graduate Program, North Carolina State University, Raleigh, North Carolina, USA.
Nowicki M; Department of Histology and Embryology, Poznan University of Medical Sciences, Poznan, Poland.
Kempisty B; Department of Histology and Embryology, Poznan University of Medical Sciences, Poznan, Poland.; Department of Anatomy, Poznan University of Medical Sciences, Poznan, Poland.; Department of Obstetrics and Gynaecology, University Hospital and Masaryk University, Brno, Czech Republic.
Antosik P; Veterinary Centre, Nicolaus Copernicus University in Torun, Torun, Poland.; Pokaż więcej
Źródło:: BioMed research international [Biomed Res Int] 2020 Feb 03; Vol. 2020, pp. 7120375. Date of Electronic Publication: 2020 Feb 03 (Print Publication: 2020).
Typ publikacji:: Journal Article
MeSH Terms:: Cell Culture Techniques*
Gene Expression Regulation*
Models, Biological*
Aquaporins/*genetics
Connexins/*genetics
Endometrium/*cytology
Epithelial Cells/*metabolism
Animals ; Aquaporins/metabolism ; Cell Proliferation/genetics ; Cell Shape ; Cells, Cultured ; Connexins/metabolism ; Female ; Swine

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