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Tytuł:
Dynamic causal modelling of immune heterogeneity.
Autorzy:
Parr T; Wellcome Centre for Human Neuroimaging, Queen Square Institute of Neurology, London, UK. .
Bhat A; Wellcome Centre for Human Neuroimaging, Queen Square Institute of Neurology, London, UK.
Zeidman P; Wellcome Centre for Human Neuroimaging, Queen Square Institute of Neurology, London, UK.
Goel A; Royal Stoke University Hospital, Stoke-on-Trent, UK.
Billig AJ; UCL Ear Institute, University College London, London, UK.
Moran R; Centre for Neuroimaging Science, Department of Neuroimaging, IoPPN, King's College London, London, UK.
Friston KJ; Wellcome Centre for Human Neuroimaging, Queen Square Institute of Neurology, London, UK.
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Źródło:
Scientific reports [Sci Rep] 2021 May 31; Vol. 11 (1), pp. 11400. Date of Electronic Publication: 2021 May 31.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antibodies, Viral/*immunology
B-Lymphocytes/*immunology
COVID-19/*immunology
SARS-CoV-2/*immunology
T-Lymphocytes/*immunology
Antibody Formation ; Bayes Theorem ; Computer Simulation ; Cross Reactions/immunology ; Humans ; Models, Immunological ; SARS-CoV-2/pathogenicity ; Viral Load
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Pseudocell Tracer-A method for inferring dynamic trajectories using scRNAseq and its application to B cells undergoing immunoglobulin class switch recombination.
Autorzy:
Reiman D; University of Illinois at Chicago, Department of Bioengineering, Chicago, Illinois, United States of America.
Manakkat Vijay GK; University of Pittsburgh, Center for Systems Immunology, Departments of Immunology and Computational and Systems Biology, Pittsburgh, Pennsylvania, United States of America.
Xu H; Key Laboratory of Growth Regulation and Translation Research of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, Zhejiang Province, China.; Institute of Biology, Westlake Institute for Advanced Study, Hangzhou, Zhejiang Province, China.
Sonin A; Moscow Institute of Physics and Technology, Dolgoprudny, Moscow Region, Russia.
Chen D; Key Laboratory of Growth Regulation and Translation Research of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, Zhejiang Province, China.; Institute of Biology, Westlake Institute for Advanced Study, Hangzhou, Zhejiang Province, China.
Salomonis N; Division of Biomedical Informatics, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States of America.
Singh H; University of Pittsburgh, Center for Systems Immunology, Departments of Immunology and Computational and Systems Biology, Pittsburgh, Pennsylvania, United States of America.
Khan AA; University of Chicago, Department of Pathology, Chicago, Illinois, United States of America.
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Źródło:
PLoS computational biology [PLoS Comput Biol] 2021 May 03; Vol. 17 (5), pp. e1008094. Date of Electronic Publication: 2021 May 03 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Supervised Machine Learning*
B-Lymphocytes/*immunology
Immunoglobulin Class Switching/*genetics
Animals ; B-Lymphocytes/metabolism ; Basic-Leucine Zipper Transcription Factors/genetics ; Computational Biology ; Computer Simulation ; Databases, Nucleic Acid ; Gene Expression ; Immunoglobulin G/genetics ; Interleukin-4/immunology ; Mice ; Mice, Inbred C57BL ; Models, Immunological ; NF-kappa B p50 Subunit/genetics ; Neural Networks, Computer ; RNA-Seq/methods ; RNA-Seq/statistics & numerical data ; Receptors, Cytokine/genetics ; Recombination, Genetic ; STAT6 Transcription Factor/genetics ; Signal Transduction ; Single-Cell Analysis/methods ; Single-Cell Analysis/statistics & numerical data
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Inferring B cell specificity for vaccines using a Bayesian mixture model.
Autorzy:
Fowler A; Department of Biostatistics, University of Liverpool, Liverpool, UK. .
Galson JD; University Children's Hospital Zurich and the Children's Research Center, University of Zurich, Zurich, Switzerland.
Trück J; University Children's Hospital Zurich and the Children's Research Center, University of Zurich, Zurich, Switzerland.
Kelly DF; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Center, Oxford, UK.
Lunter G; MRC Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK.
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Źródło:
BMC genomics [BMC Genomics] 2020 Feb 22; Vol. 21 (1), pp. 176. Date of Electronic Publication: 2020 Feb 22.
Typ publikacji:
Journal Article
MeSH Terms:
Models, Immunological*
Vaccines*
B-Lymphocytes/*immunology
Bayes Theorem ; Hepatitis B ; Humans ; Influenza, Human
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
T cell interactions with B cells during germinal center formation, a three-step model.
Autorzy:
Biram A; Department of Immunology, The Weizmann Institute of Science, Rehovot, Israel.
Davidzohn N; Department of Immunology, The Weizmann Institute of Science, Rehovot, Israel.
Shulman Z; Department of Immunology, The Weizmann Institute of Science, Rehovot, Israel.
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Źródło:
Immunological reviews [Immunol Rev] 2019 Mar; Vol. 288 (1), pp. 37-48.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Models, Immunological*
B-Lymphocytes/*immunology
Germinal Center/*immunology
T-Lymphocytes, Helper-Inducer/*immunology
Animals ; Antigens/immunology ; Cell Differentiation ; Humans ; Immunity, Humoral ; Intercellular Adhesion Molecule-1/metabolism ; Lymphocyte Activation ; Receptors, Antigen, T-Cell/metabolism ; Signal Transduction ; Signaling Lymphocytic Activation Molecule Family Member 1/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Crohn's Disease Patients in Remission Display an Enhanced Intestinal IgM⁺ B Cell Count in Concert with a Strong Activation of the Intestinal Complement System.
Autorzy:
Preisker S; Institute of Nutritional Medicine, Molecular Gastroenterology, University Hospital Schleswig-Holstein, Campus Lübeck, D-23538 Lübeck, Germany. .
Brethack AK; Institute of Nutritional Medicine, Molecular Gastroenterology, University Hospital Schleswig-Holstein, Campus Lübeck, D-23538 Lübeck, Germany. .
Bokemeyer A; Department of Medicine B, Gastroenterology and Hepatology, University Hospital Münster, 48149 Münster, Germany. .
Bettenworth D; Department of Medicine B, Gastroenterology and Hepatology, University Hospital Münster, 48149 Münster, Germany. .
Sina C; Institute of Nutritional Medicine, Molecular Gastroenterology, University Hospital Schleswig-Holstein, Campus Lübeck, D-23538 Lübeck, Germany. .
Derer S; Institute of Nutritional Medicine, Molecular Gastroenterology, University Hospital Schleswig-Holstein, Campus Lübeck, D-23538 Lübeck, Germany. .
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Źródło:
Cells [Cells] 2019 Jan 21; Vol. 8 (1). Date of Electronic Publication: 2019 Jan 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
B-Lymphocytes/*immunology
Complement Activation/*immunology
Complement System Proteins/*immunology
Crohn Disease/*immunology
Immunoglobulin M/*metabolism
Intestines/*immunology
Crohn Disease/blood ; Crohn Disease/pathology ; Feces ; Female ; Humans ; Immunologic Memory ; Intestinal Mucosa/immunology ; Intestinal Mucosa/pathology ; Lymphocyte Count ; Male ; Models, Immunological ; Remission Induction ; Up-Regulation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A mechanism of T cell dependent selection of antigen engaged Germinal Center B cells.
Autorzy:
Krishna V; Computational Biology, Discovery Sciences, Janssen Research and Development LLC., 1400 McKean Road, Spring House, PA, United States of America.
Bachman KE; Computational Biology, Discovery Sciences, Janssen Research and Development LLC., 1400 McKean Road, Spring House, PA, United States of America.
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Źródło:
PloS one [PLoS One] 2018 Aug 23; Vol. 13 (8), pp. e0200241. Date of Electronic Publication: 2018 Aug 23 (Print Publication: 2018).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antibody Affinity*
Models, Immunological*
B-Lymphocytes/*immunology
Germinal Center/*immunology
T-Lymphocytes/*immunology
Animals ; Antigens/metabolism ; Apoptosis ; Computer Simulation ; Epitopes, B-Lymphocyte/metabolism ; Epitopes, T-Lymphocyte/metabolism ; Immune Tolerance
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Optimal Sequential Immunization Can Focus Antibody Responses against Diversity Loss and Distraction.
Autorzy:
Wang S; Department of Physics and Astronomy, University of California Los Angeles, Los Angeles, California, United States of America.
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Źródło:
PLoS computational biology [PLoS Comput Biol] 2017 Jan 30; Vol. 13 (1), pp. e1005336. Date of Electronic Publication: 2017 Jan 30 (Print Publication: 2017).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Models, Genetic*
Models, Immunological*
AIDS Vaccines/*immunology
Antibody Diversity/*genetics
Antibody Diversity/*immunology
B-Lymphocytes/*immunology
AIDS Vaccines/genetics ; Antibodies, Neutralizing/genetics ; Antibodies, Neutralizing/immunology ; Antibody Affinity/genetics ; Antibody Affinity/immunology ; Antigen-Antibody Reactions/genetics ; Antigen-Antibody Reactions/immunology ; B-Lymphocytes/cytology ; Biological Evolution ; Cell Survival/genetics ; Cell Survival/immunology ; Cells, Cultured ; Computer Simulation ; Genetic Variation ; Humans ; Immunization/methods ; Immunization Schedule ; Immunogenetic Phenomena/genetics ; Models, Statistical ; Stochastic Processes
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Likelihood-Based Inference of B Cell Clonal Families.
Autorzy:
Ralph DK; Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America.
Matsen FA 4th; Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America.
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Źródło:
PLoS computational biology [PLoS Comput Biol] 2016 Oct 17; Vol. 12 (10), pp. e1005086. Date of Electronic Publication: 2016 Oct 17 (Print Publication: 2016).
Typ publikacji:
Journal Article
MeSH Terms:
Models, Genetic*
B-Lymphocytes/*immunology
High-Throughput Nucleotide Sequencing/*methods
Receptors, Antigen, B-Cell/*genetics
Receptors, Antigen, B-Cell/*immunology
Clone Cells/immunology ; Computer Simulation ; Gene Rearrangement, B-Lymphocyte/genetics ; Gene Rearrangement, B-Lymphocyte/immunology ; Models, Immunological ; Models, Statistical ; Sequence Analysis, DNA
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Enlarged colitogenic T cell population paradoxically supports colitis prevention through the B-lymphocyte-dependent peripheral generation of CD4(+)Foxp3(+) Treg cells.
Autorzy:
do Canto FB; Universidade Federal do Rio de Janeiro (UFRJ), Centro de Ciências da Saúde, Instituto de Microbiologia Paulo de Góes (IMPG), Departamento de Imunologia, Laboratório Integrado de Imunobiologia - Rio de Janeiro/RJ, Brazil.
Campos SM; Universidade Federal Fluminense (UFF), Instituto de Biologia, Departamento de Imunobiologia, Campus do Valonguinho, Outeiro de São João Batista, s/n. Niterói, RJ 24210-130 - Brazil.; Grupo de Imunologia Gastrintestinal - UFF, Campus do Valonguinho, Outeiro de São João Batista, s/n. Niterói, RJ 24210-130 - Brazil.; Programa de Pós-Graduação em Patologia - Faculdade de Medicina/UFF, Campus do Valonguinho, Outeiro de São João Batista, s/n. Niterói, RJ 24210-130 - Brazil.
Granato A; Universidade Federal do Rio de Janeiro (UFRJ), Centro de Ciências da Saúde, Instituto de Microbiologia Paulo de Góes (IMPG), Departamento de Imunologia, Laboratório Integrado de Imunobiologia - Rio de Janeiro/RJ, Brazil.
da Silva RF; Universidade Federal Fluminense (UFF), Instituto de Biologia, Departamento de Imunobiologia, Campus do Valonguinho, Outeiro de São João Batista, s/n. Niterói, RJ 24210-130 - Brazil.; Laboratório de Patologia Celular e Molecular - UFF, Campus do Valonguinho, Outeiro de São João Batista, s/n. Niterói, RJ 24210-130 - Brazil.; Programa de Pós-Graduação em Biologia das Interações - Instituto de Biologia/UFF, Campus do Valonguinho, Outeiro de São João Batista, s/n. Niterói, RJ 24210-130 - Brazil.
de Paiva LS; Universidade Federal Fluminense (UFF), Instituto de Biologia, Departamento de Imunobiologia, Campus do Valonguinho, Outeiro de São João Batista, s/n. Niterói, RJ 24210-130 - Brazil.; Programa de Pós-Graduação em Patologia - Faculdade de Medicina/UFF, Campus do Valonguinho, Outeiro de São João Batista, s/n. Niterói, RJ 24210-130 - Brazil.; Núcleo de Animais de Laboratório, Laboratório de Imunorregulação - UFF, Campus do Valonguinho, Outeiro de São João Batista, s/n. Niterói, RJ 24210-130 - Brazil.
Nóbrega A; Universidade Federal do Rio de Janeiro (UFRJ), Centro de Ciências da Saúde, Instituto de Microbiologia Paulo de Góes (IMPG), Departamento de Imunologia, Laboratório Integrado de Imunobiologia - Rio de Janeiro/RJ, Brazil.
Bellio M; Universidade Federal do Rio de Janeiro (UFRJ), Centro de Ciências da Saúde, Instituto de Microbiologia Paulo de Góes (IMPG), Departamento de Imunologia, Laboratório Integrado de Imunobiologia - Rio de Janeiro/RJ, Brazil.
Fucs R; Universidade Federal Fluminense (UFF), Instituto de Biologia, Departamento de Imunobiologia, Campus do Valonguinho, Outeiro de São João Batista, s/n. Niterói, RJ 24210-130 - Brazil.; Núcleo de Animais de Laboratório, Laboratório de Imunorregulação - UFF, Campus do Valonguinho, Outeiro de São João Batista, s/n. Niterói, RJ 24210-130 - Brazil.
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Źródło:
Scientific reports [Sci Rep] 2016 Jun 29; Vol. 6, pp. 28573. Date of Electronic Publication: 2016 Jun 29.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Models, Immunological*
B-Lymphocytes/*immunology
Colitis/*immunology
Colitis/*prevention & control
T-Lymphocytes, Regulatory/*immunology
Animals ; B-Lymphocytes/pathology ; Colitis/genetics ; Colitis/pathology ; Lymph Nodes/immunology ; Lymph Nodes/pathology ; Mesentery/immunology ; Mesentery/pathology ; Mice ; Mice, Knockout ; T-Lymphocytes, Regulatory/pathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
A Network Model to Describe the Terminal Differentiation of B Cells.
Autorzy:
Méndez A; Programa de Doctorado en Ciencias Bioquímicas, Universidad Nacional Autónoma de México, Ciudad de México, México.; Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Ciudad de México, México.
Mendoza L; Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Ciudad de México, México.; C3, Centro de Ciencias de la Complejidad, Universidad Nacional Autónoma de México, Ciudad de México, México.
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Źródło:
PLoS computational biology [PLoS Comput Biol] 2016 Jan 11; Vol. 12 (1), pp. e1004696. Date of Electronic Publication: 2016 Jan 11 (Print Publication: 2016).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Models, Immunological*
B-Lymphocytes/*immunology
Cell Differentiation/*immunology
Animals ; Cells, Cultured ; Computational Biology ; Intracellular Signaling Peptides and Proteins/metabolism ; Mice ; Signal Transduction/immunology ; T-Lymphocytes, Helper-Inducer/immunology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Exceptional Antibodies Produced by Successive Immunizations.
Autorzy:
Gearhart PJ; Laboratory of Molecular Biology and Immunology, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States of America.
Castiblanco DP; Laboratory of Molecular Biology and Immunology, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States of America.
Russell Knode LM; Laboratory of Molecular Biology and Immunology, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States of America.
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Źródło:
PLoS biology [PLoS Biol] 2015 Dec 07; Vol. 13 (12), pp. e1002321. Date of Electronic Publication: 2015 Dec 07 (Print Publication: 2015).
Typ publikacji:
Journal Article; Research Support, N.I.H., Intramural
MeSH Terms:
Immunity, Active*
Immunization, Secondary*
Immunologic Memory*
Models, Immunological*
Antibodies, Viral/*biosynthesis
B-Lymphocytes/*immunology
Viral Vaccines/*therapeutic use
Animals ; Antibodies, Viral/analysis ; Antibodies, Viral/genetics ; Antibody Affinity ; Antigens, Viral/adverse effects ; Antigens, Viral/therapeutic use ; B-Lymphocytes/metabolism ; Cytidine Deaminase/metabolism ; Humans ; Mutation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Regulation of bifurcating B cell trajectories by mutual antagonism between transcription factors IRF4 and IRF8.
Autorzy:
Xu H; Division of Immunobiology and the Center for Systems Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Chaudhri VK; Division of Immunobiology and the Center for Systems Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Wu Z; Division of Immunobiology and the Center for Systems Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Biliouris K; Division of Immunobiology and the Center for Systems Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Dienger-Stambaugh K; Division of Immunobiology and the Center for Systems Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Rochman Y; Division of Immunobiology and the Center for Systems Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Singh H; Division of Immunobiology and the Center for Systems Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
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Źródło:
Nature immunology [Nat Immunol] 2015 Dec; Vol. 16 (12), pp. 1274-81. Date of Electronic Publication: 2015 Oct 05.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
B-Lymphocytes/*immunology
Interferon Regulatory Factors/*immunology
Lymphocyte Activation/*immunology
Signal Transduction/*immunology
Algorithms ; Animals ; B-Lymphocytes/metabolism ; Blotting, Western ; Cell Differentiation/immunology ; Cells, Cultured ; Feedback, Physiological ; Flow Cytometry ; Germinal Center/cytology ; Germinal Center/immunology ; Interferon Regulatory Factors/deficiency ; Interferon Regulatory Factors/genetics ; Mice, Inbred C57BL ; Mice, Knockout ; Mice, Transgenic ; Models, Immunological ; Plasma Cells/immunology ; Plasma Cells/metabolism ; Receptors, Antigen, B-Cell/immunology ; Reverse Transcriptase Polymerase Chain Reaction ; T-Lymphocytes, Helper-Inducer/immunology ; T-Lymphocytes, Helper-Inducer/metabolism ; Transcriptome/genetics ; Transcriptome/immunology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Immunology: Fifty years of B lymphocytes.
Autorzy:
Gitlin AD; Weill Cornell/Rockefeller/Sloan-Kettering Tri-Institutional programme in New York City, New York, USA.
Nussenzweig MC; Rockefeller University in New York, New York, USA.
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Źródło:
Nature [Nature] 2015 Jan 08; Vol. 517 (7533), pp. 139-41.
Typ publikacji:
Historical Article; Journal Article
MeSH Terms:
Allergy and Immunology/*history
B-Lymphocytes/*immunology
Animals ; Antibodies/chemistry ; Antibodies/immunology ; Antibodies/therapeutic use ; Antibodies, Monoclonal/history ; Antibodies, Monoclonal/immunology ; Antigens/immunology ; Bursa of Fabricius/immunology ; Chickens/immunology ; History, 20th Century ; Humans ; Hybridomas/immunology ; Immunity, Cellular ; Immunity, Humoral ; Mice ; Models, Immunological ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/classification ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/pathology ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/therapy ; T-Lymphocytes/immunology ; Thymectomy
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Germinal center B cell depletion diminishes CD4+ follicular T helper cells in autoimmune mice.
Autorzy:
Yusuf I; Department of Respiratory, Inflammation and Autoimmunity Research, MedImmune LLC, Gaithersburg, Maryland, United States of America.
Stern J; Department of Respiratory, Inflammation and Autoimmunity Research, MedImmune LLC, Gaithersburg, Maryland, United States of America.
McCaughtry TM; Department of Respiratory, Inflammation and Autoimmunity Research, MedImmune LLC, Gaithersburg, Maryland, United States of America.
Gallagher S; Department of Respiratory, Inflammation and Autoimmunity Research, MedImmune LLC, Gaithersburg, Maryland, United States of America.
Sun H; Department of Respiratory, Inflammation and Autoimmunity Research, MedImmune LLC, Gaithersburg, Maryland, United States of America.
Gao C; Department of Antibody Discovery and Protein Engineering, MedImmune LLC, Gaithersburg, Maryland, United States of America.
Tedder T; Department of Immunology, Duke University Medical Center, Durham, North Carolina, United States of America.
Carlesso G; Department of Respiratory, Inflammation and Autoimmunity Research, MedImmune LLC, Gaithersburg, Maryland, United States of America.
Carter L; Department of Respiratory, Inflammation and Autoimmunity Research, MedImmune LLC, Gaithersburg, Maryland, United States of America.
Herbst R; Department of Respiratory, Inflammation and Autoimmunity Research, MedImmune LLC, Gaithersburg, Maryland, United States of America.
Wang Y; Department of Respiratory, Inflammation and Autoimmunity Research, MedImmune LLC, Gaithersburg, Maryland, United States of America.
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Źródło:
PloS one [PLoS One] 2014 Aug 07; Vol. 9 (8), pp. e102791. Date of Electronic Publication: 2014 Aug 07 (Print Publication: 2014).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Models, Immunological*
Autoimmune Diseases/*immunology
B-Lymphocytes/*physiology
Germinal Center/*physiology
T-Lymphocytes, Helper-Inducer/*physiology
Animals ; B-Lymphocytes/cytology ; B-Lymphocytes/immunology ; Cell Differentiation/immunology ; Germinal Center/cytology ; Germinal Center/immunology ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Mice, Inbred NZB ; Signal Transduction ; T-Lymphocytes, Helper-Inducer/cytology ; T-Lymphocytes, Helper-Inducer/immunology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
B cell-mediated antigen transport to splenic follicles.
Autorzy:
Henningsson F; Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden.
Ding Z
Heyman B
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Źródło:
Scandinavian journal of immunology [Scand J Immunol] 2014 Jan; Vol. 79 (1), pp. 73-4.
Typ publikacji:
Letter
MeSH Terms:
Antigen Presentation/*immunology
Antigens/*immunology
B-Lymphocytes/*immunology
Dendritic Cells, Follicular/*immunology
Spleen/*immunology
Animals ; B-Lymphocytes/metabolism ; Humans ; Models, Immunological ; Receptors, Antigen, B-Cell/immunology ; Receptors, Antigen, B-Cell/metabolism ; Receptors, Complement 3b/immunology ; Receptors, Complement 3d/immunology ; Receptors, IgE/immunology
Opinia redakcyjna
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Murine gammaherpesvirus M2 protein induction of IRF4 via the NFAT pathway leads to IL-10 expression in B cells.
Autorzy:
Rangaswamy US; Microbiology and Molecular Genetics Graduate Program, Emory University School of Medicine, Atlanta, Georgia, United States of America ; Department of Microbiology & Immunology, Emory University School of Medicine, Atlanta, Georgia, United States of America.
Speck SH; Department of Microbiology & Immunology, Emory University School of Medicine, Atlanta, Georgia, United States of America ; Emory Vaccine Center, Emory University School of Medicine, Atlanta, Georgia, United States of America.
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Źródło:
PLoS pathogens [PLoS Pathog] 2014 Jan; Vol. 10 (1), pp. e1003858. Date of Electronic Publication: 2014 Jan 02.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Models, Immunological*
B-Lymphocytes/*immunology
Gene Expression Regulation/*immunology
Interferon Regulatory Factors/*immunology
Interleukin-10/*immunology
NFATC Transcription Factors/*immunology
Rhadinovirus/*physiology
Viral Proteins/*immunology
Animals ; B-Lymphocytes/pathology ; Cell Line, Tumor ; Cell Proliferation/genetics ; Herpesviridae Infections/genetics ; Herpesviridae Infections/immunology ; Herpesviridae Infections/pathology ; Interferon Regulatory Factors/genetics ; Interleukin-10/genetics ; Lymphocyte Activation ; Mice ; Mice, Mutant Strains ; NFATC Transcription Factors/genetics ; Viral Proteins/genetics ; Virus Latency/genetics ; Virus Latency/immunology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
A rheostat for immune responses: the unique properties of PD-1 and their advantages for clinical application.
Autorzy:
Okazaki T; Division of Immune Regulation, Institute for Genome Research, University of Tokushima, Tokushima, Japan.
Chikuma S
Iwai Y
Fagarasan S
Honjo T
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Źródło:
Nature immunology [Nat Immunol] 2013 Dec; Vol. 14 (12), pp. 1212-8.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
B-Lymphocytes/*immunology
Immune System/*immunology
Programmed Cell Death 1 Receptor/*immunology
T-Lymphocytes/*immunology
Animals ; B-Lymphocytes/metabolism ; Humans ; Immune System/metabolism ; Immune Tolerance/immunology ; Mice ; Models, Immunological ; Programmed Cell Death 1 Receptor/metabolism ; Signal Transduction/immunology ; T-Lymphocytes/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
A dynamic model of the immune response to the onset of a tumor.
Autorzy:
Antonovsky MY; Institute of Global Climate and Ecology, Federal Service of Russia on Hydrometeorology and Monitoring of the Environment, Russian Academy of Sciences, ul. Glebovskaya 20B, Moscow, 107258, Russia.
Korzukhin MD
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Źródło:
Doklady. Biochemistry and biophysics [Dokl Biochem Biophys] 2013 Jul-Aug; Vol. 451, pp. 176-9. Date of Electronic Publication: 2013 Aug 23.
Typ publikacji:
Journal Article
MeSH Terms:
Models, Immunological*
B-Lymphocytes/*immunology
Immunity, Innate/*immunology
Neoplasms/*immunology
Precancerous Conditions/*immunology
T-Lymphocytes/*immunology
Animals ; Cell Proliferation ; Computer Simulation ; Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Differential requirement for Hoxa9 in the development and differentiation of B, NK, and DC-lineage cells from Flt3+ multipotential progenitors.
Autorzy:
Gwin K; Department of Immunology, College of Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.
Dolence JJ
Shapiro MB
Medina KL
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Źródło:
BMC immunology [BMC Immunol] 2013 Jan 30; Vol. 14, pp. 5. Date of Electronic Publication: 2013 Jan 30.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
B-Lymphocytes/*cytology
Cell Differentiation/*immunology
Cell Lineage/*immunology
Dendritic Cells/*cytology
Homeodomain Proteins/*metabolism
Killer Cells, Natural/*cytology
Multipotent Stem Cells/*cytology
Animals ; B-Lymphocytes/immunology ; Bone Marrow Cells/cytology ; Bone Marrow Cells/immunology ; Dendritic Cells/immunology ; Homeostasis/immunology ; Killer Cells, Natural/immunology ; Lymphoid Progenitor Cells/cytology ; Lymphoid Progenitor Cells/immunology ; Mice ; Mice, Inbred C57BL ; Models, Immunological ; Multipotent Stem Cells/immunology ; Receptors, Interleukin-7/metabolism ; fms-Like Tyrosine Kinase 3/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
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