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Wyszukujesz frazę ""Models, Immunological"" wg kryterium: Temat


Tytuł:
ISOTOPE: ISOform-guided prediction of epiTOPEs in cancer.
Autorzy:
Trincado JL; Josep Carreras Leukemia Research Institute, Badalona, Spain.
Reixachs-Solé M; Australian National University, Canberra, Australia.; EMBL Australia Partner Laboratory Network at the Australian National University, Canberra, Australia.
Pérez-Granado J; Research Programme on Biomedical Informatics (GRIB), Hospital del Mar Medical Research Institute (IMIM), Dept. of Experimental and Health Sciences, Pompeu Fabra University (UPF), Barcelona, Spain.
Fugmann T; Philochem AG, Otelfingen, Switzerland.
Sanz F; Research Programme on Biomedical Informatics (GRIB), Hospital del Mar Medical Research Institute (IMIM), Dept. of Experimental and Health Sciences, Pompeu Fabra University (UPF), Barcelona, Spain.
Yokota J; National Cancer Center Research Institute (NCCRI), Tokyo, Japan.
Eyras E; Australian National University, Canberra, Australia.; EMBL Australia Partner Laboratory Network at the Australian National University, Canberra, Australia.; Catalan Institution for Research and Advanced Studies, Barcelona, Spain.; Hospital del Mar Medical Research Institute (IMIM), Barcelona, Spain.
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Źródło:
PLoS computational biology [PLoS Comput Biol] 2021 Sep 16; Vol. 17 (9), pp. e1009411. Date of Electronic Publication: 2021 Sep 16 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Epitopes/*genetics
Epitopes/*immunology
Neoplasms/*genetics
Neoplasms/*immunology
Alternative Splicing/genetics ; Alternative Splicing/immunology ; Breast Neoplasms/genetics ; Breast Neoplasms/immunology ; Carcinoma, Small Cell/genetics ; Carcinoma, Small Cell/immunology ; Cell Line, Tumor ; Computational Biology ; Female ; Histocompatibility Antigens Class I/genetics ; Histocompatibility Antigens Class I/immunology ; Humans ; Immunotherapy ; Lung Neoplasms/genetics ; Lung Neoplasms/immunology ; Male ; Melanoma/genetics ; Melanoma/immunology ; Models, Genetic ; Models, Immunological ; Mutation ; Neoplasms/therapy ; Protein Isoforms/genetics ; Protein Isoforms/immunology ; RNA Splicing/genetics ; RNA Splicing/immunology ; RNA-Seq
Czasopismo naukowe
Tytuł:
Progress and challenge for computational quantification of tissue immune cells.
Autorzy:
Chen Z; Suzhou Institute of Systems Medicine, Center for Systems Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Jiangsu, Suzhou, China.
Wu A; Suzhou Institute of Systems Medicine, Center for Systems Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Jiangsu, Suzhou, China.
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Źródło:
Briefings in bioinformatics [Brief Bioinform] 2021 Sep 02; Vol. 22 (5).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Immune System*
Models, Immunological*
Lymphocytes/*immunology
Monocytes/*immunology
Neoplasm Proteins/*genetics
Neoplasms/*immunology
Animals ; Computer Simulation ; Fibroblasts/classification ; Fibroblasts/immunology ; Fibroblasts/pathology ; Gene Expression Regulation, Neoplastic ; Humans ; Lymphocytes/classification ; Lymphocytes/pathology ; Mice ; MicroRNAs/genetics ; MicroRNAs/immunology ; Monocytes/classification ; Monocytes/pathology ; Neoplasm Proteins/immunology ; Neoplasms/genetics ; Neoplasms/pathology ; RNA, Messenger/genetics ; RNA, Messenger/immunology ; Signal Transduction
Czasopismo naukowe
Tytuł:
Unveiling the immune infiltrate modulation in cancer and response to immunotherapy by MIXTURE-an enhanced deconvolution method.
Autorzy:
Fernández EA; National Council of Scientific Research.
Mahmoud YD; Translational Immuno Oncology Lab at the Institute of Biology and Experimental Medicine in Buenos Aires, Argentina.
Veigas F; Translational Immuno Oncology Lab at the Institute of Biology and Experimental Medicine.
Rocha D; Universidad Nacional de Córdoba, Argentina.
Miranda M; Universidad Catolica de Cordoba.
Merlo J; Translational Immuno Oncology Lab at the Institute of Biology and Experimental Medicine.
Balzarini M; CONICET.
Lujan HD; Argentinian National Council for Scientific and Technical Research.
Rabinovich GA; National Council of Scientific Research.
Girotti MR; Translational Immuno Oncology Lab at the Institute of Biology and Experimental Medicine in Buenos Aires, Argentina.
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Źródło:
Briefings in bioinformatics [Brief Bioinform] 2021 Jul 20; Vol. 22 (4).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Databases, Nucleic Acid*
Immunotherapy*
Models, Immunological*
Neoplasms*/genetics
Neoplasms*/immunology
Neoplasms*/therapy
Support Vector Machine*
Gene Expression Regulation, Neoplastic/*immunology
Transcriptome/*immunology
Humans
Czasopismo naukowe
Tytuł:
Tumor-Associated Macrophages: Combination of Therapies, the Approach to Improve Cancer Treatment.
Autorzy:
Moeini P; Plant Virology Research Center, Shiraz University, Shiraz 71441-65186, Iran.
Niedźwiedzka-Rystwej P; Institute of Biology, University of Szczecin, 71-412 Szczecin, Poland.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Jul 05; Vol. 22 (13). Date of Electronic Publication: 2021 Jul 05.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Neoplasms/*immunology
Neoplasms/*therapy
Tumor-Associated Macrophages/*immunology
Animals ; Combined Modality Therapy ; Female ; Humans ; Immunity, Innate ; Immunotherapy/methods ; Male ; Models, Immunological ; Tumor Microenvironment/immunology ; Tumor-Associated Macrophages/classification
Czasopismo naukowe
Tytuł:
Cellular metabolism dictates T cell effector function in health and disease.
Autorzy:
Kolan SS; Division for Molecular Nutrition, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.
Li G; Division for Molecular Nutrition, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.
Wik JA; Department of Pathology, Oslo University Hospital, Rikshopitalet, Oslo, Norway.
Malachin G; Division for Molecular Nutrition, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.
Guo S; Division for Molecular Nutrition, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.
Kolan P; Division for Molecular Nutrition, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.
Skålhegg BS; Division for Molecular Nutrition, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.
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Źródło:
Scandinavian journal of immunology [Scand J Immunol] 2020 Nov; Vol. 92 (5), pp. e12956. Date of Electronic Publication: 2020 Sep 19.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Autoimmunity/*immunology
Energy Metabolism/*immunology
Lymphocyte Activation/*immunology
Neoplasms/*immunology
T-Lymphocyte Subsets/*immunology
T-Lymphocytes/*immunology
Animals ; Cellular Microenvironment/immunology ; Humans ; Models, Immunological ; Neoplasms/metabolism ; T-Lymphocyte Subsets/metabolism ; T-Lymphocytes/metabolism
Czasopismo naukowe
Tytuł:
QSP-IO: A Quantitative Systems Pharmacology Toolbox for Mechanistic Multiscale Modeling for Immuno-Oncology Applications.
Autorzy:
Sové RJ; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Jafarnejad M; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Zhao C; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Wang H; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Ma H; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Popel AS; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.; The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
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Źródło:
CPT: pharmacometrics & systems pharmacology [CPT Pharmacometrics Syst Pharmacol] 2020 Sep; Vol. 9 (9), pp. 484-497. Date of Electronic Publication: 2020 Sep 07.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Immune Checkpoint Proteins/*pharmacology
Immunotherapy/*adverse effects
Neoplasms/*drug therapy
Pharmacology/*methods
Allergy and Immunology ; Biomarkers, Tumor/immunology ; Computer Simulation ; Drug Development ; Drug Discovery ; Drug Industry/trends ; Evaluation Studies as Topic ; Humans ; Medical Oncology ; Models, Biological ; Models, Immunological ; Models, Theoretical ; Neoplasms/immunology ; Neoplasms/pathology ; Treatment Outcome ; Tumor Microenvironment/drug effects
Czasopismo naukowe
Tytuł:
Ferroptosis, necroptosis, and pyroptosis in anticancer immunity.
Autorzy:
Tang R; Department of Pancreatic Surgery, Fudan University Shanghai Cancer Center, No. 270 Dong'An Road, Shanghai, China.; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.; Shanghai Pancreatic Cancer Institute, No. 270 Dong'An Road, Shanghai, 200032, China.; Pancreatic Cancer Institute, Fudan University, Shanghai, China.
Xu J; Department of Pancreatic Surgery, Fudan University Shanghai Cancer Center, No. 270 Dong'An Road, Shanghai, China.; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.; Shanghai Pancreatic Cancer Institute, No. 270 Dong'An Road, Shanghai, 200032, China.; Pancreatic Cancer Institute, Fudan University, Shanghai, China.
Zhang B; Department of Pancreatic Surgery, Fudan University Shanghai Cancer Center, No. 270 Dong'An Road, Shanghai, China.; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.; Shanghai Pancreatic Cancer Institute, No. 270 Dong'An Road, Shanghai, 200032, China.; Pancreatic Cancer Institute, Fudan University, Shanghai, China.
Liu J; Department of Pancreatic Surgery, Fudan University Shanghai Cancer Center, No. 270 Dong'An Road, Shanghai, China.; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.; Shanghai Pancreatic Cancer Institute, No. 270 Dong'An Road, Shanghai, 200032, China.; Pancreatic Cancer Institute, Fudan University, Shanghai, China.
Liang C; Department of Pancreatic Surgery, Fudan University Shanghai Cancer Center, No. 270 Dong'An Road, Shanghai, China.; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.; Shanghai Pancreatic Cancer Institute, No. 270 Dong'An Road, Shanghai, 200032, China.; Pancreatic Cancer Institute, Fudan University, Shanghai, China.
Hua J; Department of Pancreatic Surgery, Fudan University Shanghai Cancer Center, No. 270 Dong'An Road, Shanghai, China.; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.; Shanghai Pancreatic Cancer Institute, No. 270 Dong'An Road, Shanghai, 200032, China.; Pancreatic Cancer Institute, Fudan University, Shanghai, China.
Meng Q; Department of Pancreatic Surgery, Fudan University Shanghai Cancer Center, No. 270 Dong'An Road, Shanghai, China.; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.; Shanghai Pancreatic Cancer Institute, No. 270 Dong'An Road, Shanghai, 200032, China.; Pancreatic Cancer Institute, Fudan University, Shanghai, China.
Yu X; Department of Pancreatic Surgery, Fudan University Shanghai Cancer Center, No. 270 Dong'An Road, Shanghai, China. .; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China. .; Shanghai Pancreatic Cancer Institute, No. 270 Dong'An Road, Shanghai, 200032, China. .; Pancreatic Cancer Institute, Fudan University, Shanghai, China. .
Shi S; Department of Pancreatic Surgery, Fudan University Shanghai Cancer Center, No. 270 Dong'An Road, Shanghai, China. .; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China. .; Shanghai Pancreatic Cancer Institute, No. 270 Dong'An Road, Shanghai, 200032, China. .; Pancreatic Cancer Institute, Fudan University, Shanghai, China. .
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Źródło:
Journal of hematology & oncology [J Hematol Oncol] 2020 Aug 10; Vol. 13 (1), pp. 110. Date of Electronic Publication: 2020 Aug 10.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Ferroptosis/*immunology
Immune Checkpoint Inhibitors/*pharmacology
Necroptosis/*immunology
Neoplasms/*immunology
Pyroptosis/*immunology
Adaptive Immunity ; Alarmins/physiology ; Animals ; Antigens, Neoplasm/immunology ; Autophagy ; Ferroptosis/drug effects ; Humans ; Immune Checkpoint Inhibitors/therapeutic use ; Lymphocyte Subsets/immunology ; Lymphocytes, Tumor-Infiltrating/immunology ; Mice ; Models, Immunological ; NF-kappa B/metabolism ; Necroptosis/drug effects ; Neoplasm Proteins/physiology ; Neoplasm Transplantation ; Neoplasms/drug therapy ; Neoplasms/pathology ; Protein Kinases/physiology ; Pyroptosis/drug effects
Czasopismo naukowe
Tytuł:
Dendritic cell biology and its role in tumor immunotherapy.
Autorzy:
Wang Y; State Key Laboratory of Respiratory Disease, Affiliated Cancer Hospital & Institute of Guangzhou Medical University, Guangzhou, 510095, China.; Laboratory of Oncology, Center for Molecular Medicine, School of Basic Medicine, Faculty of Medicine, Yangtze University, 1 Nanhuan Road, Jingzhou, 434023, Hubei, China.; Department of Biochemistry and Molecular Biology, School of Basic Medicine, Faculty of Medicine, Yangtze University, Jingzhou, 434023, Hubei, China.; Department of Gynaecology, Comprehensive Cancer Center, Hannover Medical School, 30625, Hannover, Germany.
Xiang Y; Laboratory of Oncology, Center for Molecular Medicine, School of Basic Medicine, Faculty of Medicine, Yangtze University, 1 Nanhuan Road, Jingzhou, 434023, Hubei, China.; Department of Biochemistry and Molecular Biology, School of Basic Medicine, Faculty of Medicine, Yangtze University, Jingzhou, 434023, Hubei, China.
Xin VW; Stanford University, Stanford, CA, 94305, USA.
Wang XW; Laboratory of Oncology, Center for Molecular Medicine, School of Basic Medicine, Faculty of Medicine, Yangtze University, 1 Nanhuan Road, Jingzhou, 434023, Hubei, China.; Department of Laboratory Medicine, School of Basic Medicine, Faculty of Medicine, Yangtze University, 1 Nanhuan Road, Jingzhou, 434023, Hubei, China.
Peng XC; Laboratory of Oncology, Center for Molecular Medicine, School of Basic Medicine, Faculty of Medicine, Yangtze University, 1 Nanhuan Road, Jingzhou, 434023, Hubei, China.; Department of Pathophysiology, School of Basic Medicine, Faculty of Medicine, Yangtze University, Jingzhou, 434023, Hubei, China.
Liu XQ; Laboratory of Oncology, Center for Molecular Medicine, School of Basic Medicine, Faculty of Medicine, Yangtze University, 1 Nanhuan Road, Jingzhou, 434023, Hubei, China.; Department of Biochemistry and Molecular Biology, School of Basic Medicine, Faculty of Medicine, Yangtze University, Jingzhou, 434023, Hubei, China.; Department of Medical Imaging, School of Basic Medicine, Faculty of Medicine, Yangtze University, Jingzhou, 434023, Hubei, China.
Wang D; Laboratory of Oncology, Center for Molecular Medicine, School of Basic Medicine, Faculty of Medicine, Yangtze University, 1 Nanhuan Road, Jingzhou, 434023, Hubei, China.; Department of Biochemistry and Molecular Biology, School of Basic Medicine, Faculty of Medicine, Yangtze University, Jingzhou, 434023, Hubei, China.
Li N; Department of Oncology, First Affiliated Hospital of Yangtze University, Jingzhou, Hubei, China.
Cheng JT; Laboratory of Oncology, Center for Molecular Medicine, School of Basic Medicine, Faculty of Medicine, Yangtze University, 1 Nanhuan Road, Jingzhou, 434023, Hubei, China.; Department of Biochemistry and Molecular Biology, School of Basic Medicine, Faculty of Medicine, Yangtze University, Jingzhou, 434023, Hubei, China.
Lyv YN; Institute for Infectious Diseases and Endemic Diseases Prevention and Control, Beijing Center for Diseases Prevention and Control, Beijing, 100013, China.
Cui SZ; State Key Laboratory of Respiratory Disease, Affiliated Cancer Hospital & Institute of Guangzhou Medical University, Guangzhou, 510095, China.
Ma Z; Laboratory of Oncology, Center for Molecular Medicine, School of Basic Medicine, Faculty of Medicine, Yangtze University, 1 Nanhuan Road, Jingzhou, 434023, Hubei, China. .; Department of Biochemistry and Molecular Biology, School of Basic Medicine, Faculty of Medicine, Yangtze University, Jingzhou, 434023, Hubei, China. .
Zhang Q; State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, 510275, China. .; Institute of Sun Yat-sen University in Shenzhen, Shenzhen, China. .
Xin HW; Laboratory of Oncology, Center for Molecular Medicine, School of Basic Medicine, Faculty of Medicine, Yangtze University, 1 Nanhuan Road, Jingzhou, 434023, Hubei, China. hongwu_.; Department of Biochemistry and Molecular Biology, School of Basic Medicine, Faculty of Medicine, Yangtze University, Jingzhou, 434023, Hubei, China. hongwu_.; People's Hospital of Lianjiang, Lianjiang, 524400, Guangdong, China. hongwu_.
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Źródło:
Journal of hematology & oncology [J Hematol Oncol] 2020 Aug 03; Vol. 13 (1), pp. 107. Date of Electronic Publication: 2020 Aug 03.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Immunotherapy*
Antigen Presentation/*immunology
Dendritic Cells/*immunology
Neoplasms/*therapy
Animals ; Antigens, Neoplasm/immunology ; Autophagy/immunology ; Clinical Trials as Topic ; Exosomes/immunology ; Histocompatibility Antigens Class I/immunology ; Humans ; Immunologic Memory ; Immunologic Surveillance ; Lectins, C-Type/immunology ; Lymphocyte Activation ; Lymphocyte Subsets/immunology ; Mice ; Models, Immunological ; Neoplasms/immunology ; Protein Conformation ; Receptors, Antigen, T-Cell/chemistry ; Receptors, Antigen, T-Cell/immunology ; Receptors, Fc/immunology ; Receptors, Immunologic/immunology ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
Influence of Innate Immunity on Cancer Cell Stemness.
Autorzy:
Pastò A; Department of Inflammation and Immunology, Humanitas Clinical and Research Center-IRCCS-, via Manzoni 56, 20089 Rozzano (MI), Italy.
Consonni FM; Department of Pharmaceutical Sciences, University of Eastern Piedmont, A. Avogadro, via Bovio 6, 28100 Novara, Italy.
Sica A; Department of Inflammation and Immunology, Humanitas Clinical and Research Center-IRCCS-, via Manzoni 56, 20089 Rozzano (MI), Italy.; Department of Pharmaceutical Sciences, University of Eastern Piedmont, A. Avogadro, via Bovio 6, 28100 Novara, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2020 May 09; Vol. 21 (9). Date of Electronic Publication: 2020 May 09.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Immunity, Innate*
Neoplasms/*immunology
Neoplastic Stem Cells/*cytology
Animals ; Cell Self Renewal ; Cell Transformation, Neoplastic/immunology ; Cytokines/physiology ; HLA Antigens/immunology ; Humans ; Immunotherapy ; Killer Cells, Natural/immunology ; Macrophage Activation ; Models, Immunological ; Monitoring, Immunologic ; Neoplasm Metastasis ; Neoplasms/pathology ; Neoplastic Stem Cells/immunology ; Neutrophils/immunology ; Rats ; T-Lymphocyte Subsets/immunology ; Tumor Escape/immunology ; Tumor Microenvironment/immunology
Czasopismo naukowe
Tytuł:
Immunohistochemical phenotyping of T cells, granulocytes, and phagocytes in the muscle of cancer patients: association with radiologically defined muscle mass and gene expression.
Autorzy:
Anoveros-Barrera A; Department of Agricultural, Food & Nutritional Science, Faculty of Agricultural, Life and Environmental Sciences, University of Alberta, 4-002 Li Ka Shing Centre, Edmonton, Alberta, T6G 2P5, Canada.
Bhullar AS; Department of Agricultural, Food & Nutritional Science, Faculty of Agricultural, Life and Environmental Sciences, University of Alberta, 4-002 Li Ka Shing Centre, Edmonton, Alberta, T6G 2P5, Canada.
Stretch C; Department of Oncology, University of Calgary, Calgary, Alberta, Canada.
Dunichand-Hoedl AR; Department of Agricultural, Food & Nutritional Science, Faculty of Agricultural, Life and Environmental Sciences, University of Alberta, 4-002 Li Ka Shing Centre, Edmonton, Alberta, T6G 2P5, Canada.
Martins KJB; Department of Agricultural, Food & Nutritional Science, Faculty of Agricultural, Life and Environmental Sciences, University of Alberta, 4-002 Li Ka Shing Centre, Edmonton, Alberta, T6G 2P5, Canada.
Rieger A; Flow Cytometry Facility, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.
Bigam D; Department of Surgery, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.
McMullen T; Department of Surgery, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.
Bathe OF; Department of Oncology and Department of Surgery, University of Calgary, Calgary, Alberta, Canada.
Putman CT; Faculty of Kinesiology, Sport, and Recreation, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.
Field CJ; Department of Agricultural, Food & Nutritional Science, Faculty of Agricultural, Life and Environmental Sciences, University of Alberta, 4-002 Li Ka Shing Centre, Edmonton, Alberta, T6G 2P5, Canada.
Baracos VE; Department of Oncology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.
Mazurak VC; Department of Agricultural, Food & Nutritional Science, Faculty of Agricultural, Life and Environmental Sciences, University of Alberta, 4-002 Li Ka Shing Centre, Edmonton, Alberta, T6G 2P5, Canada. .
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Źródło:
Skeletal muscle [Skelet Muscle] 2019 Sep 14; Vol. 9 (1), pp. 24. Date of Electronic Publication: 2019 Sep 14.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Granulocytes/*immunology
Muscle, Skeletal/*immunology
Neoplasms/*immunology
Phagocytes/*immunology
T-Lymphocytes/*immunology
Adaptive Immunity ; Adult ; Aged ; Aged, 80 and over ; Female ; Gene Expression ; Granulocytes/pathology ; Humans ; Immunity, Innate ; Immunophenotyping ; Male ; Middle Aged ; Models, Immunological ; Muscle, Skeletal/diagnostic imaging ; Muscle, Skeletal/pathology ; Neoplasms/genetics ; Neoplasms/pathology ; Phagocytes/pathology ; T-Lymphocytes/classification ; T-Lymphocytes/pathology
Czasopismo naukowe
Tytuł:
Molecular model linking Th2 polarized M2 tumour-associated macrophages with deaminase-mediated cancer progression mutation signatures.
Autorzy:
Mamrot J; GMDxCo Pty Ltd, Melbourne, Victoria, Australia.
Balachandran S; Blood Cell Development and Function Program, Fox Chase Cancer Center, Philadelphia, Pennsylvania.
Steele EJ; CYO'Connor ERADE Village Foundation, Perth, Western Australia, Australia.; Melville Analytics Pty Ltd, Melbourne, Victoria, Australia.
Lindley RA; GMDxCo Pty Ltd, Melbourne, Victoria, Australia.; Faculty of Medicine, Dentistry & Health Sciences, Department of Clinical Pathology, University of Melbourne, Melbourne, Victoria, Australia.
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Źródło:
Scandinavian journal of immunology [Scand J Immunol] 2019 May; Vol. 89 (5), pp. e12760. Date of Electronic Publication: 2019 Mar 18.
Typ publikacji:
Journal Article
MeSH Terms:
Models, Immunological*
Recombination, Genetic*
Carcinogenesis/*genetics
Macrophages/*immunology
Mutation/*genetics
Neoplasms/*genetics
Th2 Cells/*immunology
Animals ; Cell Differentiation ; Cell Movement ; DNA Mutational Analysis ; Extracellular Vesicles/metabolism ; Humans ; Lymphocyte Activation ; Models, Theoretical ; Nucleoside Deaminases/metabolism ; Transcriptome
Czasopismo naukowe
Tytuł:
Study of tumor growth indicates the existence of an "immunological threshold" separating states of pro- and antitumoral peritumoral inflammation.
Autorzy:
Brú A; Applied Mathematics Department, Universidad Complutense de Madrid, Madrid, Spain.
Gómez-Castro D; Applied Mathematics Department, Universidad Complutense de Madrid, Madrid, Spain.; Instituto de Matemática Interdisciplinar, Universidad Complutense de Madrid, Madrid, Spain.
Vila L; Laboratory of Angiology, Vascular Biology and Inflammation, IIB-Sant Pau, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Brú I; Centro de Salud La Estación, Talavera de la Reina, Spain.
Souto JC; Department of Hematology, IIB-Sant Pau, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.; Institut Josep Carreras contra la Leucemia, Barcelona, Spain.
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Źródło:
PloS one [PLoS One] 2018 Nov 02; Vol. 13 (11), pp. e0202823. Date of Electronic Publication: 2018 Nov 02 (Print Publication: 2018).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Inflammation/*immunology
Neoplasms/*immunology
Neutrophils/*immunology
Cell Proliferation ; Computer Simulation ; HT29 Cells ; Humans ; Immunity ; Inflammation/pathology ; Models, Immunological ; Neoplasms/pathology ; Neutrophils/pathology ; Phagocytosis
Czasopismo naukowe
Tytuł:
Applications of mechanistic modelling to clinical and experimental immunology: an emerging technology to accelerate immunotherapeutic discovery and development.
Autorzy:
Brown LV; Wolfson Centre for Mathematical Biology, Mathematical Institute, University of Oxford, Oxford, UK.
Gaffney EA; Wolfson Centre for Mathematical Biology, Mathematical Institute, University of Oxford, Oxford, UK.
Wagg J; Pharmaceutical Sciences, Clinical Pharmacology, Roche Innovation Center, Basel, Switzerland.
Coles MC; Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK.
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Źródło:
Clinical and experimental immunology [Clin Exp Immunol] 2018 Sep; Vol. 193 (3), pp. 284-292.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Models, Immunological*
Immunotherapy/*methods
Infections/*immunology
Neoplasms/*immunology
T-Lymphocytes/*immunology
Animals ; Biomedical Research ; Datasets as Topic ; Drug Development ; Drug Discovery ; Humans ; Immunotherapy/trends ; Lymphocyte Activation ; Machine Learning ; Neoplasm Metastasis
Czasopismo naukowe
Tytuł:
Cancer immunotherapy with CAR-T cells - behold the future.
Autorzy:
Graham C; King's College London, London, UK .
Hewitson R; NHS England, UK.
Pagliuca A
Benjamin R; King's College Hospital NHS Foundation Trust, London, UK.
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Źródło:
Clinical medicine (London, England) [Clin Med (Lond)] 2018 Aug; Vol. 18 (4), pp. 324-328.
Typ publikacji:
Journal Article
MeSH Terms:
Immunotherapy*/adverse effects
Immunotherapy*/methods
Immunotherapy, Adoptive*/adverse effects
Immunotherapy, Adoptive*/methods
Neoplasms/*therapy
Brain Diseases/etiology ; Cytokines/metabolism ; Humans ; Models, Immunological ; Receptors, Antigen, T-Cell/metabolism ; Receptors, Chimeric Antigen/metabolism
Czasopismo naukowe
Tytuł:
Inhibition of interleukin-12 and/or interleukin-23 for the treatment of psoriasis: What is the evidence for an effect on malignancy?
Autorzy:
Ergen EN; Department of Dermatology, University of Alabama at Birmingham, Birmingham, AL, USA.
Yusuf N; Department of Dermatology, University of Alabama at Birmingham, Birmingham, AL, USA.
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Źródło:
Experimental dermatology [Exp Dermatol] 2018 Jul; Vol. 27 (7), pp. 737-747.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Interleukin-12/*antagonists & inhibitors
Interleukin-23/*antagonists & inhibitors
Neoplasms/*etiology
Psoriasis/*immunology
Psoriasis/*therapy
Animals ; Clinical Trials as Topic ; Dermatologic Agents/adverse effects ; Dermatologic Agents/therapeutic use ; Disease Models, Animal ; Humans ; Immunity, Cellular ; Interleukin-12/chemistry ; Interleukin-12/immunology ; Interleukin-23/chemistry ; Interleukin-23/immunology ; Mice ; Models, Immunological ; Product Surveillance, Postmarketing ; Psoriasis/complications ; Receptors, Interleukin/deficiency ; Receptors, Interleukin/genetics ; Receptors, Interleukin-12/deficiency ; Receptors, Interleukin-12/genetics ; T-Lymphocytes/immunology ; Ustekinumab/adverse effects ; Ustekinumab/therapeutic use
Czasopismo naukowe
Tytuł:
Regulatory T cells: a potential target in cancer immunotherapy.
Autorzy:
Shitara K; Department of Gastroenterology and Gastrointestinal Oncology, National Cancer Center Hospital East, Chiba, Japan.
Nishikawa H; Division of Cancer Immunology, Research Institute/EPOC, National Cancer Center, Tokyo/Chiba, Japan.; Department of Immunology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
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Źródło:
Annals of the New York Academy of Sciences [Ann N Y Acad Sci] 2018 Apr; Vol. 1417 (1), pp. 104-115. Date of Electronic Publication: 2018 Mar 22.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Immunotherapy/*methods
Neoplasms/*immunology
Neoplasms/*therapy
T-Lymphocytes, Regulatory/*immunology
Antibodies, Monoclonal/therapeutic use ; CTLA-4 Antigen/antagonists & inhibitors ; CTLA-4 Antigen/immunology ; Glucocorticoid-Induced TNFR-Related Protein/antagonists & inhibitors ; Glucocorticoid-Induced TNFR-Related Protein/immunology ; HSP70 Heat-Shock Proteins/antagonists & inhibitors ; Humans ; Indoleamine-Pyrrole 2,3,-Dioxygenase/antagonists & inhibitors ; Interleukin-2 Receptor alpha Subunit/antagonists & inhibitors ; Interleukin-2 Receptor alpha Subunit/immunology ; Models, Immunological ; Phosphoinositide-3 Kinase Inhibitors ; Receptors, CCR4/antagonists & inhibitors ; Receptors, CCR4/immunology ; Receptors, OX40/antagonists & inhibitors ; Receptors, OX40/immunology ; T-Lymphocytes, Regulatory/classification ; Transforming Growth Factor beta/antagonists & inhibitors ; Vascular Endothelial Growth Factor A/antagonists & inhibitors ; Vascular Endothelial Growth Factor A/immunology
Czasopismo naukowe
Tytuł:
T-cell metabolism governing activation, proliferation and differentiation; a modular view.
Autorzy:
Dimeloe S; Immunobiology Laboratory, Department of Biomedicine, University of Basel, Basel, Switzerland.
Burgener AV; Immunobiology Laboratory, Department of Biomedicine, University of Basel, Basel, Switzerland.
Grählert J; Immunobiology Laboratory, Department of Biomedicine, University of Basel, Basel, Switzerland.
Hess C; Immunobiology Laboratory, Department of Biomedicine, University of Basel, Basel, Switzerland.
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Źródło:
Immunology [Immunology] 2017 Jan; Vol. 150 (1), pp. 35-44. Date of Electronic Publication: 2016 Aug 23.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Models, Immunological*
Autoimmune Diseases/*immunology
Infections/*immunology
Neoplasms/*immunology
T-Lymphocytes/*physiology
Animals ; Cell Differentiation ; Cell Proliferation ; Humans ; Lymphocyte Activation
Czasopismo naukowe
Tytuł:
Energy parasites trigger oncogene mutation.
Autorzy:
Pokorný J; a Institute of Physics, Czech Academy of Sciences , Prague , Czech Republic ;
Pokorný J; a Institute of Physics, Czech Academy of Sciences , Prague , Czech Republic ;
Jandová A; b Institute of Photonics and Electronics, Czech Academy of Sciences , Prague , Czech Republic ;
Kobilková J; c 1st Faculty of Medicine, Department of Obstetrics and Gynaecology , Charles University , Prague , Czech Republic ;
Vrba J; d Faculty of Electrical Engineering , Czech Technical University in Prague , Prague , Czech Republic ;
Vrba J Jr; e Faculty of Biomedical Engineering , Czech Technical University in Kladno , Kladno , Czech Republic.
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Źródło:
International journal of radiation biology [Int J Radiat Biol] 2016 Oct; Vol. 92 (10), pp. 577-82. Date of Electronic Publication: 2016 Sep 07.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Electromagnetic Fields*
Mutation/*genetics
Neoplasms/*genetics
Neoplasms/*immunology
Oncogenes/*genetics
Oncogenes/*immunology
Computer Simulation ; Humans ; Lactate dehydrogenase-elevating virus/physiology ; Models, Chemical ; Models, Genetic ; Models, Immunological ; Mutation/radiation effects ; Neoplasms/virology ; Oncogenes/radiation effects ; T-Lymphocytes/immunology ; T-Lymphocytes/radiation effects ; T-Lymphocytes/virology
Czasopismo naukowe
Tytuł:
Targeting regulatory T cells in tumors.
Autorzy:
Liu C; Department of Immunology, University of Pittsburgh, Pittsburgh, PA, USA.
Workman CJ; Department of Immunology, University of Pittsburgh, Pittsburgh, PA, USA.
Vignali DA; Department of Immunology, University of Pittsburgh, Pittsburgh, PA, USA.; Tumor Microenvironment Center, University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA.
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Źródło:
The FEBS journal [FEBS J] 2016 Jul; Vol. 283 (14), pp. 2731-48. Date of Electronic Publication: 2016 Mar 01.
Typ publikacji:
Journal Article; Review; Research Support, N.I.H., Extramural
MeSH Terms:
Neoplasms/*immunology
Neoplasms/*therapy
T-Lymphocytes, Regulatory/*immunology
Animals ; Antineoplastic Agents/pharmacology ; Cell Membrane/immunology ; Cytokines/biosynthesis ; Cytotoxicity, Immunologic ; Humans ; Immunotherapy ; Lymphocyte Depletion ; Lymphocytes, Tumor-Infiltrating/immunology ; Models, Immunological ; Peripheral Tolerance ; T-Lymphocytes, Regulatory/drug effects ; Tumor Microenvironment/immunology
Czasopismo naukowe
Tytuł:
Pregnancy is a model for tumors, not transplantation.
Autorzy:
Beaman KD; Clinical Immunology Laboratory, Department of Microbiology and Immunology, Rosalind Franklin University of Medicine and Science, North Chicago, IL, USA.
Jaiswal MK; Clinical Immunology Laboratory, Department of Microbiology and Immunology, Rosalind Franklin University of Medicine and Science, North Chicago, IL, USA.
Katara GK; Clinical Immunology Laboratory, Department of Microbiology and Immunology, Rosalind Franklin University of Medicine and Science, North Chicago, IL, USA.
Kulshreshta A; Clinical Immunology Laboratory, Department of Microbiology and Immunology, Rosalind Franklin University of Medicine and Science, North Chicago, IL, USA.
Pamarthy S; Clinical Immunology Laboratory, Department of Microbiology and Immunology, Rosalind Franklin University of Medicine and Science, North Chicago, IL, USA.
Ibrahim S; Clinical Immunology Laboratory, Department of Microbiology and Immunology, Rosalind Franklin University of Medicine and Science, North Chicago, IL, USA.
Kwak-Kim J; Clinical Immunology Laboratory, Department of Microbiology and Immunology, Rosalind Franklin University of Medicine and Science, North Chicago, IL, USA.
Gilman-Sachs A; Clinical Immunology Laboratory, Department of Microbiology and Immunology, Rosalind Franklin University of Medicine and Science, North Chicago, IL, USA.
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Źródło:
American journal of reproductive immunology (New York, N.Y. : 1989) [Am J Reprod Immunol] 2016 Jul; Vol. 76 (1), pp. 3-7.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Models, Immunological*
Maternal-Fetal Exchange/*immunology
Neoplasms/*immunology
Placenta/*immunology
Animals ; Female ; Humans ; Pregnancy
Czasopismo naukowe

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