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    Wyświetlanie 1-19 z 19
    Podgląd okładki
    Tytuł :
    MKKS is a centrosome-shuttling protein degraded by disease-causing mutations via CHIP-mediated ubiquitination
    Index Terms :
    Animals
    Bardet-Biedl Syndrome/*genetics
    Cell Line
    Centrosome/*metabolism
    Cytosol/metabolism
    Glutamic Acid/genetics
    Glycine/genetics
    Group II Chaperonins
    Humans
    Mice
    Microtubules/metabolism
    Molecular Chaperones/*metabolism
    Mutant Proteins/metabolism
    Mutation/*genetics
    Proteasome Inhibitors
    Protein Processing, Post-Translational
    Protein Structure, Quaternary
    Protein Transport
    Solubility
    Ubiquitin-Protein Ligases/*metabolism
    Ubiquitination
    Journal Article
    Tytuły dodatkowe :
    MKKS is a centrosome-shuttling protein degraded by disease-causing mutations via CHIP-mediated ubiquitination
    URL :
    http://jairo.nii.ac.jp/0083/00248149">http://jairo.nii.ac.jp/0083/00248149
    10.1091/mbc.E07-07-0631
    Zasób elektroniczny
    Szczegóły
    Podgląd okładki
    Tytuł :
    Vtc5, a Novel Subunit of the Vacuolar Transporter Chaperone Complex, Regulates Polyphosphate Synthesis and Phosphate Homeostasis in Yeast.
    Index Terms :
    Carrier Proteins/genetics; Carrier Proteins/metabolism; Molecular Chaperones/genetics; Molecular Chaperones/metabolism; Polyphosphates/metabolism; Saccharomyces cerevisiae/genetics; Saccharomyces cerevisiae/metabolism; Saccharomyces cerevisiae Proteins/genetics; Saccharomyces cerevisiae Proteins/metabolism
    info:eu-repo/semantics/article
    article
    URL :
    http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_7BF982ABD76F8">http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_7BF982ABD76F8
    Zasób elektroniczny
    Szczegóły
    Podgląd okładki
    Tytuł :
    The co-chaperone p23 controls root development through the modulation of auxin distribution in the Arabidopsis root meristem.
    Index Terms :
    Arabidopsis/genetics; Arabidopsis/growth & development; Arabidopsis Proteins/genetics; Arabidopsis Proteins/metabolism; Gene Expression Regulation, Developmental; Gene Expression Regulation, Plant; Indoleacetic Acids/metabolism; Meristem/metabolism; Molecular Chaperones/genetics; Molecular Chaperones/metabolism; Plant Growth Regulators/metabolism; Plant Roots/growth & development; Plant Roots/metabolism
    info:eu-repo/semantics/article
    article
    URL :
    http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_81ACC5AF64D55">http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_81ACC5AF64D55
    Zasób elektroniczny
    Szczegóły
    Podgląd okładki
    Tytuł :
    A P39R mutation at the N-terminal domain of human αB-crystallin regulates its oligomeric state and chaperone-like activity.
    Index Terms :
    Small heat shock protein
    Molecular chaperone
    Quaternary assembly
    Protein aggregation
    Secondary structure
    Cataract
    Amino Acid Sequence
    Arginine/chemistry
    Arginine/genetics
    Arginine/metabolism
    Circular Dichroism
    Humans
    Molecular Chaperones/chemistry
    Molecular Chaperones/genetics
    Molecular Chaperones/metabolism
    Molecular Sequence Data
    Point Mutation
    Proline/chemistry
    Proline/genetics
    Proline/metabolism
    Protein Multimerization
    Protein Structure, Secondary
    Protein Structure, Tertiary
    Recombinant Proteins/chemistry
    Recombinant Proteins/genetics
    Recombinant Proteins/metabolism
    alpha-Crystallin B Chain/chemistry
    alpha-Crystallin B Chain/genetics
    alpha-Crystallin B Chain/metabolism
    Journal Article
    Źródło :
    Biochemical and biophysical research communications
    URL :
    http://hdl.handle.net/2433/167502">http://hdl.handle.net/2433/167502
    10.1016/j.bbrc.2012.07.138
    Zasób elektroniczny
    Szczegóły
    Podgląd okładki
    Tytuł :
    Crystal structure of a thermophilic GrpE protein: insight into thermosensing function for the DnaK chaperone system.
    Index Terms :
    unfolding
    heat-shock response
    thermosensor
    thermal stability
    protein dynamics
    Amino Acid Sequence
    Bacterial Proteins/chemistry
    Bacterial Proteins/genetics
    Bacterial Proteins/metabolism
    Crystallography, X-Ray
    Heat-Shock Proteins/chemistry
    Heat-Shock Proteins/genetics
    Heat-Shock Proteins/metabolism
    Models, Molecular
    Molecular Chaperones/chemistry
    Molecular Chaperones/genetics
    Molecular Chaperones/metabolism
    Molecular Sequence Data
    Protein Structure, Tertiary
    Recombinant Proteins/chemistry
    Recombinant Proteins/genetics
    Recombinant Proteins/metabolism
    Sequence Homology, Amino Acid
    Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
    Static Electricity
    Temperature
    Thermus thermophilus/chemistry
    Thermus thermophilus/genetics
    Thermus thermophilus/metabolism
    Journal Article
    URL :
    http://hdl.handle.net/2433/132547">http://hdl.handle.net/2433/132547
    10.1016/j.jmb.2009.12.028
    Zasób elektroniczny
    Szczegóły
    Podgląd okładki
    Tytuł :
    Causes and cures for endoplasmic reticulum stress in lipotoxic beta-cell dysfunction
    Index Terms :
    Enseignement des sciences
    Biologie
    Biologie moléculaire
    Biologie cellulaire
    Biologie générale
    Diabétologie
    Apoptosis
    Calcium -- metabolism
    Diabetes Mellitus, Type 2 -- metabolism -- therapy
    Endoplasmic Reticulum -- drug effects -- pathology -- physiology
    Fatty Acids, Nonesterified -- metabolism
    Humans
    Insulin-Secreting Cells -- drug effects -- metabolism -- pathology
    Molecular Chaperones -- metabolism
    Protein Unfolding
    Signal Transduction
    Stress, Physiological -- drug effects -- physiology
    Diabetes
    Endoplasmic reticulum stress
    Free fatty acids
    Islets
    Lipotoxicity
    Oleate
    Palmitate
    Pancreatic β-cells
    Unfolded protein response
    info:eu-repo/semantics/article
    info:ulb-repo/semantics/articlePeerReview
    info:ulb-repo/semantics/openurl/article
    URL :
    http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/184535">http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/184535
    http://worldcat.org/search?q=on:EQY+http://difusion-oai.ulb.ac.be/oai/request+DCG_ENTIRE_REPOSITORY+CNTCOLL">http://worldcat.org/search?q=on:EQY+http://difusion-oai.ulb.ac.be/oai/request+DCG_ENTIRE_REPOSITORY+CNTCOLL
    Zasób elektroniczny
    Szczegóły
    Podgląd okładki
    Tytuł :
    Crystal structure of a thermophilic GrpE protein: insight into thermosensing function for the DnaK chaperone system.
    Index Terms :
    unfolding
    heat-shock response
    thermosensor
    thermal stability
    protein dynamics
    Amino Acid Sequence
    Bacterial Proteins/chemistry
    Bacterial Proteins/genetics
    Bacterial Proteins/metabolism
    Crystallography, X-Ray
    Heat-Shock Proteins/chemistry
    Heat-Shock Proteins/genetics
    Heat-Shock Proteins/metabolism
    Models, Molecular
    Molecular Chaperones/chemistry
    Molecular Chaperones/genetics
    Molecular Chaperones/metabolism
    Molecular Sequence Data
    Protein Structure, Tertiary
    Recombinant Proteins/chemistry
    Recombinant Proteins/genetics
    Recombinant Proteins/metabolism
    Sequence Homology, Amino Acid
    Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
    Static Electricity
    Temperature
    Thermus thermophilus/chemistry
    Thermus thermophilus/genetics
    Thermus thermophilus/metabolism
    Journal Article
    Źródło :
    Journal of molecular biology
    URL :
    http://hdl.handle.net/2433/132547">http://hdl.handle.net/2433/132547
    10.1016/j.jmb.2009.12.028
    Zasób elektroniczny
    Szczegóły
    Podgląd okładki
    Tytuł :
    Post-transcriptional Regulation of Genes Encoding Anti-microbial Peptides in Drosophila
    Index Terms :
    Sciences bio-médicales et agricoles
    3' Untranslated Regions -- genetics
    3' Untranslated Regions -- metabolism
    Animals
    Antimicrobial Cationic Peptides -- biosynthesis
    Antimicrobial Cationic Peptides -- genetics
    Cell Line
    Chromosomal Proteins, Non-Histone -- genetics
    Chromosomal Proteins, Non-Histone -- metabolism
    Drosophila Proteins -- genetics
    Drosophila Proteins -- metabolism
    Drosophila melanogaster
    Gram-Negative Bacteria -- chemistry
    Molecular Chaperones -- genetics
    Molecular Chaperones -- metabolism
    Peptidoglycan -- chemistry
    Peptidoglycan -- pharmacology
    RNA Stability -- drug effects
    RNA Stability -- physiology
    RNA-Binding Proteins -- genetics
    RNA-Binding Proteins -- metabolism
    Retinoblastoma-Binding Protein 4
    Signal Transduction -- drug effects
    Signal Transduction -- physiology
    Transcription, Genetic -- physiology
    Tristetraprolin -- genetics
    Tristetraprolin -- metabolism
    info:eu-repo/semantics/article
    info:ulb-repo/semantics/articlePeerReview
    info:ulb-repo/semantics/openurl/article
    URL :
    http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/50970">http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/50970
    http://worldcat.org/search?q=on:EQY+http://difusion-oai.ulb.ac.be/oai/request+DCG_ENTIRE_REPOSITORY+CNTCOLL">http://worldcat.org/search?q=on:EQY+http://difusion-oai.ulb.ac.be/oai/request+DCG_ENTIRE_REPOSITORY+CNTCOLL
    Zasób elektroniczny
    Szczegóły
    Podgląd okładki
    Tytuł :
    Knocking down galectin 1 in human hs683 glioblastoma cells impairs both angiogenesis and endoplasmic reticulum stress responses.
    Index Terms :
    Sciences bio-médicales et agricoles
    Animals
    Antineoplastic Agents, Alkylating -- pharmacology
    Brain Neoplasms -- genetics
    Brain Neoplasms -- metabolism
    Brain Neoplasms -- therapy
    Cell Line, Tumor
    Dacarbazine -- analogs & derivatives
    Dacarbazine -- pharmacology
    Down-Regulation -- drug effects
    Down-Regulation -- genetics
    Endoplasmic Reticulum -- drug effects
    Endoplasmic Reticulum -- genetics
    Endoplasmic Reticulum -- metabolism
    Endoribonucleases -- drug effects
    Endoribonucleases -- genetics
    Endoribonucleases -- metabolism
    Female
    Galectin 1 -- genetics
    Gene Expression Regulation, Neoplastic -- drug effects
    Gene Expression Regulation, Neoplastic -- genetics
    Gene Silencing -- physiology
    Gene Therapy -- methods
    Glioblastoma -- genetics
    Glioblastoma -- metabolism
    Glioblastoma -- therapy
    HSP40 Heat-Shock Proteins -- drug effects
    HSP40 Heat-Shock Proteins -- genetics
    HSP40 Heat-Shock Proteins -- metabolism
    Humans
    Membrane Proteins -- drug effects
    Membrane Proteins -- genetics
    Membrane Proteins -- metabolism
    Mice
    Molecular Chaperones -- drug effects
    Molecular Chaperones -- genetics
    Molecular Chaperones -- metabolism
    Neovascularization, Pathologic -- genetics
    Neovascularization, Pathologic -- metabolism
    Neovascularization, Pathologic -- therapy
    Oxidative Stress -- genetics
    Protein-Serine-Threonine Kinases -- drug effects
    Protein-Serine-Threonine Kinases -- genetics
    Protein-Serine-Threonine Kinases -- metabolism
    Proteins -- drug effects
    Proteins -- genetics
    Proteins -- metabolism
    RNA Interference -- drug effects
    RNA Interference -- physiology
    RNA, Small Interfering -- genetics
    RNA, Small Interfering -- pharmacology
    RNA, Small Interfering -- therapeutic use
    Signal Transduction -- genetics
    Transplantation, Heterologous
    Angiogenesis
    Endoplasmic reticulum stress
    Galectin 1
    Glioblastoma
    Hypoxia
    info:eu-repo/semantics/article
    info:ulb-repo/semantics/articlePeerReview
    info:ulb-repo/semantics/openurl/article
    URL :
    http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/51203">http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/51203
    http://worldcat.org/search?q=on:EQY+http://difusion-oai.ulb.ac.be/oai/request+DCG_ENTIRE_REPOSITORY+CNTCOLL">http://worldcat.org/search?q=on:EQY+http://difusion-oai.ulb.ac.be/oai/request+DCG_ENTIRE_REPOSITORY+CNTCOLL
    Zasób elektroniczny
    Szczegóły
    Podgląd okładki
    Tytuł :
    Cell surface targeting of VPAC1 receptors: evidence for implication of a quality control system and the proteasome.
    Index Terms :
    Sciences bio-médicales et agricoles
    Animals
    CHO Cells
    Cell Membrane -- metabolism
    Cricetinae
    Cricetulus
    Molecular Chaperones -- metabolism
    Mutation
    Proteasome Endopeptidase Complex -- metabolism
    Protein Transport
    Receptors, Vasoactive Intestinal Polypeptide, Type I -- chemistry
    Receptors, Vasoactive Intestinal Polypeptide, Type I -- genetics
    Receptors, Vasoactive Intestinal Polypeptide, Type I -- metabolism
    Temperature
    Ubiquitin -- metabolism
    Cell surface expression
    Glycosylation
    GPCR
    Proteasome
    Trafficking
    VIP receptor
    VPAC1
    info:eu-repo/semantics/article
    info:ulb-repo/semantics/articlePeerReview
    info:ulb-repo/semantics/openurl/article
    URL :
    http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/50363">http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/50363
    http://worldcat.org/search?q=on:EQY+http://difusion-oai.ulb.ac.be/oai/request+DCG_ENTIRE_REPOSITORY+CNTCOLL">http://worldcat.org/search?q=on:EQY+http://difusion-oai.ulb.ac.be/oai/request+DCG_ENTIRE_REPOSITORY+CNTCOLL
    Zasób elektroniczny
    Szczegóły
    Podgląd okładki
    Tytuł :
    IpgB1 and IpgB2, two homologous effectors secreted via the Mxi-Spa type III secretion apparatus, cooperate to mediate polarized cell invasion and inflammatory potential of Shigella flexenri.
    Index Terms :
    Sciences bio-médicales et agricoles
    Amino Acid Sequence
    Animals
    Antigens, Bacterial
    Bacterial Outer Membrane Proteins -- metabolism
    Bacterial Proteins -- metabolism
    Caco-2 Cells
    Dysentery, Bacillary -- microbiology
    Dysentery, Bacillary -- pathology
    Female
    Hela Cells
    Humans
    Inflammation -- pathology
    Mice
    Mice, Inbred BALB C
    Molecular Chaperones -- metabolism
    Molecular Sequence Data
    Point Mutation
    Sequence Alignment
    Shigella flexneri -- metabolism
    Shigella flexneri -- pathogenicity
    Virulence
    rac1 GTP-Binding Protein -- genetics
    rac1 GTP-Binding Protein -- metabolism
    Invasion
    Shigella
    Tight junction
    Type III secretion
    info:eu-repo/semantics/article
    info:ulb-repo/semantics/articlePeerReview
    info:ulb-repo/semantics/openurl/article
    URL :
    http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/50114">http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/50114
    http://worldcat.org/search?q=on:EQY+http://difusion-oai.ulb.ac.be/oai/request+DCG_ENTIRE_REPOSITORY+CNTCOLL">http://worldcat.org/search?q=on:EQY+http://difusion-oai.ulb.ac.be/oai/request+DCG_ENTIRE_REPOSITORY+CNTCOLL
    Zasób elektroniczny
    Szczegóły
    Podgląd okładki
    Tytuł :
    The endoplasmic reticulum in pancreatic beta cells of type 2 diabetes patients.
    Index Terms :
    Sciences bio-médicales et agricoles
    Aged
    Apoptosis -- physiology
    Cells, Cultured
    DNA-Binding Proteins -- genetics
    DNA-Binding Proteins -- metabolism
    Diabetes Mellitus, Type 2 -- genetics
    Diabetes Mellitus, Type 2 -- pathology
    Diabetes Mellitus, Type 2 -- physiopathology
    Endoplasmic Reticulum -- metabolism
    Endoplasmic Reticulum -- pathology
    Endoplasmic Reticulum -- physiology
    Endoplasmic Reticulum -- ultrastructure
    Female
    Gene Expression -- drug effects
    Gene Expression Profiling
    Glucose -- pharmacology
    Heat-Shock Proteins -- genetics
    Heat-Shock Proteins -- metabolism
    Humans
    Insulin -- secretion
    Insulin-Secreting Cells -- pathology
    Insulin-Secreting Cells -- physiology
    Insulin-Secreting Cells -- secretion
    Insulin-Secreting Cells -- ultrastructure
    Islets of Langerhans -- drug effects
    Islets of Langerhans -- metabolism
    Male
    Middle Aged
    Molecular Chaperones -- genetics
    Molecular Chaperones -- metabolism
    Nuclear Proteins -- genetics
    Nuclear Proteins -- metabolism
    Oligonucleotide Array Sequence Analysis
    Transcription Factor CHOP -- genetics
    Transcription Factor CHOP -- metabolism
    Transcription Factors
    Beta cell
    BiP
    C/EBP homologous protein
    CHOP
    Endoplasmic reticulum
    Immunoglobulin heavy chain binding protein
    Unfolded protein response
    X-box binding protein 1
    XBP-1
    info:eu-repo/semantics/article
    info:ulb-repo/semantics/articlePeerReview
    info:ulb-repo/semantics/openurl/article
    URL :
    http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/52501">http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/52501
    http://worldcat.org/search?q=on:EQY+http://difusion-oai.ulb.ac.be/oai/request+DCG_ENTIRE_REPOSITORY+CNTCOLL">http://worldcat.org/search?q=on:EQY+http://difusion-oai.ulb.ac.be/oai/request+DCG_ENTIRE_REPOSITORY+CNTCOLL
    Zasób elektroniczny
    Szczegóły
    Podgląd okładki
    Tytuł :
    Type 2 Diabetes Mellitus as a Conformational Disease
    Index Terms :
    Amino Acid Sequence
    Amyloid /chemistry/metabolism
    Diabetes Mellitus
    Type 2 /metabolism
    Endoplasmic Reticulum /metabolism
    Humans
    Islets of Langerhans
    Islets of Langerhans Transplantation
    Islets of Langerhans /metabolism
    Molecular Chaperones /metabolism
    Molecular Sequence Data
    Oxidative Stress
    Protein Conformation
    Protein Folding
    URL :
    http://www.joplink.net/prev/200507/02.html">http://www.joplink.net/prev/200507/02.html
    http://www.doaj.org/doaj?func=openurl&genre=article&issn=15908577&date=2005&volume=6&issue=4&spage=287">http://www.doaj.org/doaj?func=openurl&genre=article&issn=15908577&date=2005&volume=6&issue=4&spage=287
    Zasób elektroniczny
    Szczegóły
    Podgląd okładki
    Tytuł :
    IpgD, a protein secreted by the type III secretion machinery of Shigella flexneri, is chaperoned by IpgE and implicated in entry focus formation.
    Index Terms :
    Sciences bio-médicales et agricoles
    Bacterial Proteins -- metabolism
    Base Sequence
    Culture Media
    DNA Primers
    Hela Cells
    Humans
    Membrane Fusion
    Molecular Chaperones -- metabolism
    Shigella flexneri -- physiology
    info:eu-repo/semantics/article
    info:ulb-repo/semantics/articlePeerReview
    info:ulb-repo/semantics/openurl/article
    URL :
    http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/50124">http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/50124
    http://worldcat.org/search?q=on:EQY+http://difusion-oai.ulb.ac.be/oai/request+DCG_ENTIRE_REPOSITORY+CNTCOLL">http://worldcat.org/search?q=on:EQY+http://difusion-oai.ulb.ac.be/oai/request+DCG_ENTIRE_REPOSITORY+CNTCOLL
    Zasób elektroniczny
    Szczegóły
      Wyświetlanie 1-19 z 19

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