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Tytuł:
Molecular Pathological Diagnosis of Thyroid Tumors Using Spatially Resolved Metabolomics.
Autorzy:
Huang L; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
Mao X; Department of Pathology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China.
Sun C; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
Li T; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
Song X; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
Li J; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
Gao S; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
Zhang R; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.; NMPA Key Laboratory for Safety Research and Evaluation of Innovative Drug, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
Chen J; Department of Pathology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China.
He J; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.; NMPA Key Laboratory for Safety Research and Evaluation of Innovative Drug, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
Abliz Z; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.; Center for Imaging and Systems Biology, School of Pharmacy, Minzu University of China, Beijing 100081, China.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2022 Feb 18; Vol. 27 (4). Date of Electronic Publication: 2022 Feb 18.
Typ publikacji:
Journal Article
MeSH Terms:
Biomarkers, Tumor*
Metabolomics*/methods
Molecular Diagnostic Techniques*
Thyroid Neoplasms/*diagnosis
Thyroid Neoplasms/*metabolism
Fluorescent Antibody Technique ; Humans ; Immunohistochemistry ; Metabolome ; Prognosis ; ROC Curve ; Spectrometry, Mass, Electrospray Ionization ; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization ; Thyroid Neoplasms/etiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Microsatellite Instability Analysis (MSA) for Bladder Cancer: Past History and Future Directions.
Autorzy:
Moon C; Department of Otolaryngology-Head and Neck Surgery, The Johns Hopkins Medical Institution, Cancer Research Building II, 5M3, 1550 Orleans Street, Baltimore, MD 21205, USA.; HJM Cancer Research Foundation Corporation, 10606 Candlewick Road, Lutherville, MD 21093, USA.; BCD Innovations USA, 10606 Candlewick Road, Lutherville, MD 21093, USA.
Gordon M; HJM Cancer Research Foundation Corporation, 10606 Candlewick Road, Lutherville, MD 21093, USA.; BCD Innovations USA, 10606 Candlewick Road, Lutherville, MD 21093, USA.
Moon D; HJM Cancer Research Foundation Corporation, 10606 Candlewick Road, Lutherville, MD 21093, USA.
Reynolds T; NEXT Bio-Research Services, LLC, 11601 Ironbridge Road, Suite 101, Chester, VA 23831, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Nov 28; Vol. 22 (23). Date of Electronic Publication: 2021 Nov 28.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Microsatellite Instability*
Molecular Diagnostic Techniques*
Biomarkers, Tumor/*urine
Carcinoma, Transitional Cell/*diagnosis
Urinary Bladder Neoplasms/*diagnosis
Carcinoma, Transitional Cell/genetics ; Carcinoma, Transitional Cell/urine ; Humans ; Microsatellite Repeats ; Urinary Bladder Neoplasms/genetics ; Urinary Bladder Neoplasms/urine
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
A Timely Update of Immunohistochemistry and Molecular Classification in the Diagnosis and Risk Assessment of Endometrial Carcinomas.
Autorzy:
Wang M; From the Department of Pathology, Yale University School of Medicine, New Haven, Connecticut.
Hui P; From the Department of Pathology, Yale University School of Medicine, New Haven, Connecticut.
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Źródło:
Archives of pathology & laboratory medicine [Arch Pathol Lab Med] 2021 Nov 01; Vol. 145 (11), pp. 1367-1378.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Biomarkers, Tumor*/analysis
Biomarkers, Tumor*/genetics
Immunohistochemistry*
Molecular Diagnostic Techniques*
Carcinoma/*diagnosis
Endometrial Neoplasms/*diagnosis
Carcinoma/chemistry ; Carcinoma/genetics ; Carcinoma/pathology ; DNA Copy Number Variations ; DNA Polymerase II/genetics ; Endometrial Neoplasms/chemistry ; Endometrial Neoplasms/genetics ; Endometrial Neoplasms/pathology ; Female ; Gene Dosage ; Humans ; Microsatellite Instability ; Mutation ; Poly-ADP-Ribose Binding Proteins/genetics ; Predictive Value of Tests ; Prognosis ; Terminology as Topic ; Tumor Suppressor Protein p53/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
A Brief Overview and Update on Major Molecular Genomic Alterations in Solid, Bone and Soft Tissue Tumors, and Hematopoietic As Well As Lymphoid Malignancies.
Autorzy:
Zhang W; From the Department of Pathology and Laboratory Medicine, University of Wisconsin, Madison (W. Zhang).; W. Zhang and Yao are co-first authors.; W. Zhang and H.-Y. Wang are co-senior authors and supervised this manuscript equally.
Yao J; the Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York (Yao).; W. Zhang and Yao are co-first authors.
Zhong M; the Department of Pathology, Yale University School of Medicine, New Haven, Connecticut (Zhong).
Zhang Y; the Department of Pathology and Laboratory Medicine, Hospital for Special Surgery, New York, New York (Y. Zhang).; the Department of Pathology and Laboratory Medicine, Weill Cornell College of Medicine, New York, New York (Y. Zhang).
Guo X; the Department of Pathology, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, New York (Guo).
Wang HY; the Department of Pathology, University of California San Diego, La Jolla (Wang).; W. Zhang and H.-Y. Wang are co-senior authors and supervised this manuscript equally.
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Źródło:
Archives of pathology & laboratory medicine [Arch Pathol Lab Med] 2021 Nov 01; Vol. 145 (11), pp. 1358-1366.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Genomics*
Molecular Diagnostic Techniques*
Biomarkers, Tumor/*genetics
Bone Neoplasms/*genetics
Hematologic Neoplasms/*genetics
Lymphoproliferative Disorders/*genetics
Soft Tissue Neoplasms/*genetics
Bone Neoplasms/pathology ; Gene Expression Profiling ; Hematologic Neoplasms/pathology ; High-Throughput Nucleotide Sequencing ; Humans ; Lymphoproliferative Disorders/pathology ; Predictive Value of Tests ; Soft Tissue Neoplasms/pathology ; Transcriptome
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Optimizing Nanopore sequencing-based detection of structural variants enables individualized circulating tumor DNA-based disease monitoring in cancer patients.
Autorzy:
Valle-Inclan JE; Department of Genetics, Center for Molecular Medicine, University Medical Center Utrecht and Utrecht University, Utrecht, The Netherlands.; Oncode Institute, Utrecht, The Netherlands.
Stangl C; Department of Genetics, Center for Molecular Medicine, University Medical Center Utrecht and Utrecht University, Utrecht, The Netherlands.; Oncode Institute, Utrecht, The Netherlands.; Division of Molecular Oncology, Netherlands Cancer Institute, Amsterdam, The Netherlands.
de Jong AC; Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.
van Dessel LF; Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.
van Roosmalen MJ; Department of Genetics, Center for Molecular Medicine, University Medical Center Utrecht and Utrecht University, Utrecht, The Netherlands.; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.
Helmijr JCA; Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.
Renkens I; Department of Genetics, Center for Molecular Medicine, University Medical Center Utrecht and Utrecht University, Utrecht, The Netherlands.
Janssen R; Department of Genetics, Center for Molecular Medicine, University Medical Center Utrecht and Utrecht University, Utrecht, The Netherlands.; Oncode Institute, Utrecht, The Netherlands.
de Blank S; Department of Genetics, Center for Molecular Medicine, University Medical Center Utrecht and Utrecht University, Utrecht, The Netherlands.
de Witte CJ; Department of Genetics, Center for Molecular Medicine, University Medical Center Utrecht and Utrecht University, Utrecht, The Netherlands.; Oncode Institute, Utrecht, The Netherlands.
Martens JWM; Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.
Jansen MPHM; Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.
Lolkema MP; Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands. .
Kloosterman WP; Department of Genetics, Center for Molecular Medicine, University Medical Center Utrecht and Utrecht University, Utrecht, The Netherlands. .; Cyclomics, Utrecht, The Netherlands. .; Frame Cancer Therapeutics, Amsterdam, The Netherlands. .
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Źródło:
Genome medicine [Genome Med] 2021 May 18; Vol. 13 (1), pp. 86. Date of Electronic Publication: 2021 May 18.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Biomarkers, Tumor*
Circulating Tumor DNA*
Genomic Structural Variation*
Molecular Diagnostic Techniques*/methods
Molecular Diagnostic Techniques*/standards
Nanopore Sequencing*
Neoplasms/*diagnosis
Neoplasms/*genetics
Computational Biology/methods ; Female ; Humans ; Liquid Biopsy/methods ; Male ; Organ Specificity/genetics ; Real-Time Polymerase Chain Reaction ; Reproducibility of Results ; Sensitivity and Specificity ; Sequence Analysis, DNA
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Pan-Cancer Biomarkers: Changing the Landscape of Molecular Testing.
Autorzy:
Yao J; From the Diagnostic Molecular Service, Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
Arcila ME; From the Diagnostic Molecular Service, Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
Ladanyi M; From the Diagnostic Molecular Service, Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
Hechtman JF; From the Diagnostic Molecular Service, Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
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Źródło:
Archives of pathology & laboratory medicine [Arch Pathol Lab Med] 2021 Jun 01; Vol. 145 (6), pp. 692-698.
Typ publikacji:
Journal Article
MeSH Terms:
Microsatellite Instability*
Mutation*
Biomarkers, Tumor/*genetics
High-Throughput Nucleotide Sequencing/*methods
Molecular Diagnostic Techniques/*methods
Neoplasms/*genetics
B7-H1 Antigen/genetics ; B7-H1 Antigen/metabolism ; Biomarkers, Tumor/metabolism ; Fibroblast Growth Factors/genetics ; Fibroblast Growth Factors/metabolism ; Humans ; Immunohistochemistry/methods ; In Situ Hybridization, Fluorescence/methods ; Molecular Diagnostic Techniques/trends ; Neoplasms/diagnosis ; Neoplasms/metabolism ; Programmed Cell Death 1 Receptor/genetics ; Programmed Cell Death 1 Receptor/metabolism ; Receptors, Fibroblast Growth Factor/genetics ; Receptors, Fibroblast Growth Factor/metabolism ; Reverse Transcriptase Polymerase Chain Reaction/methods
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
The many faces of solitary fibrous tumor; diversity of histological features, differential diagnosis and role of molecular studies and surrogate markers in avoiding misdiagnosis and predicting the behavior.
Autorzy:
Tariq MU; Section of Histopathology, Department of Pathology and Laboratory Medicine, Aga Khan University Hospital, Karachi, Pakistan.
Din NU; Section of Histopathology, Department of Pathology and Laboratory Medicine, Aga Khan University Hospital, Karachi, Pakistan.
Abdul-Ghafar J; Department of Pathology and Clinical Laboratory, French Medical Institute for Mothers and Children (FMIC), Kabul, Afghanistan. .
Park YK; Emeritus Professor, Kyung Hee University, School of Medicine Vice President of Asia, International Academy of Pathology, U2Labs, Jangwon Medical Foundation 68 Geoma-ro, Songpa-gu, Seoul, 05755, South Korea.
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Źródło:
Diagnostic pathology [Diagn Pathol] 2021 Apr 20; Vol. 16 (1), pp. 32. Date of Electronic Publication: 2021 Apr 20.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Molecular Diagnostic Techniques*
Solitary Fibrous Tumors*/chemistry
Solitary Fibrous Tumors*/genetics
Solitary Fibrous Tumors*/secondary
Solitary Fibrous Tumors*/surgery
Biomarkers, Tumor/*genetics
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Biomarkers, Tumor/analysis ; Child ; Diagnosis, Differential ; Diagnostic Errors ; Female ; Gene Fusion ; Humans ; Immunohistochemistry ; Male ; Middle Aged ; Mutation ; Predictive Value of Tests ; Prognosis ; Repressor Proteins/genetics ; STAT6 Transcription Factor/genetics ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Emerging Advances of Detection Strategies for Tumor-Derived Exosomes.
Autorzy:
Cheng H; College of Pharmacy, Hangzhou Normal University, Hangzhou 311121, China.; Key Laboratory of Elemene Class Anti-Cancer Chinese Medicines, Hangzhou Normal University, Hangzhou 311121, China.; Engineering Laboratory of Development and Application of Traditional Chinese Medicines, Hangzhou Normal University, Hangzhou 311121, China.; Collaborative Innovation Center of Traditional Chinese Medicines of Zhejiang Province, Hangzhou Normal University, Hangzhou 311121, China.
Yang Q; College of Pharmacy, Hangzhou Normal University, Hangzhou 311121, China.; Key Laboratory of Elemene Class Anti-Cancer Chinese Medicines, Hangzhou Normal University, Hangzhou 311121, China.; Engineering Laboratory of Development and Application of Traditional Chinese Medicines, Hangzhou Normal University, Hangzhou 311121, China.; Collaborative Innovation Center of Traditional Chinese Medicines of Zhejiang Province, Hangzhou Normal University, Hangzhou 311121, China.
Wang R; College of Pharmacy, Hangzhou Normal University, Hangzhou 311121, China.; Key Laboratory of Elemene Class Anti-Cancer Chinese Medicines, Hangzhou Normal University, Hangzhou 311121, China.; Engineering Laboratory of Development and Application of Traditional Chinese Medicines, Hangzhou Normal University, Hangzhou 311121, China.; Collaborative Innovation Center of Traditional Chinese Medicines of Zhejiang Province, Hangzhou Normal University, Hangzhou 311121, China.
Luo R; College of Pharmacy, Hangzhou Normal University, Hangzhou 311121, China.; Key Laboratory of Elemene Class Anti-Cancer Chinese Medicines, Hangzhou Normal University, Hangzhou 311121, China.; Engineering Laboratory of Development and Application of Traditional Chinese Medicines, Hangzhou Normal University, Hangzhou 311121, China.; Collaborative Innovation Center of Traditional Chinese Medicines of Zhejiang Province, Hangzhou Normal University, Hangzhou 311121, China.
Zhu S; Public Health Institutes, Hangzhou Normal University, Hangzhou 311121, China.
Li M; College of Pharmacy, Hangzhou Normal University, Hangzhou 311121, China.; Key Laboratory of Elemene Class Anti-Cancer Chinese Medicines, Hangzhou Normal University, Hangzhou 311121, China.; Engineering Laboratory of Development and Application of Traditional Chinese Medicines, Hangzhou Normal University, Hangzhou 311121, China.; Collaborative Innovation Center of Traditional Chinese Medicines of Zhejiang Province, Hangzhou Normal University, Hangzhou 311121, China.
Li W; College of Pharmacy, Hangzhou Normal University, Hangzhou 311121, China.; Key Laboratory of Elemene Class Anti-Cancer Chinese Medicines, Hangzhou Normal University, Hangzhou 311121, China.; Engineering Laboratory of Development and Application of Traditional Chinese Medicines, Hangzhou Normal University, Hangzhou 311121, China.; Collaborative Innovation Center of Traditional Chinese Medicines of Zhejiang Province, Hangzhou Normal University, Hangzhou 311121, China.
Chen C; College of Pharmacy, Hangzhou Normal University, Hangzhou 311121, China.; Key Laboratory of Elemene Class Anti-Cancer Chinese Medicines, Hangzhou Normal University, Hangzhou 311121, China.; Engineering Laboratory of Development and Application of Traditional Chinese Medicines, Hangzhou Normal University, Hangzhou 311121, China.; Collaborative Innovation Center of Traditional Chinese Medicines of Zhejiang Province, Hangzhou Normal University, Hangzhou 311121, China.
Zou Y; College of Pharmacy, Hangzhou Normal University, Hangzhou 311121, China.; Key Laboratory of Elemene Class Anti-Cancer Chinese Medicines, Hangzhou Normal University, Hangzhou 311121, China.; Engineering Laboratory of Development and Application of Traditional Chinese Medicines, Hangzhou Normal University, Hangzhou 311121, China.; Collaborative Innovation Center of Traditional Chinese Medicines of Zhejiang Province, Hangzhou Normal University, Hangzhou 311121, China.
Huang Z; College of Pharmacy, Hangzhou Normal University, Hangzhou 311121, China.; Key Laboratory of Elemene Class Anti-Cancer Chinese Medicines, Hangzhou Normal University, Hangzhou 311121, China.; Engineering Laboratory of Development and Application of Traditional Chinese Medicines, Hangzhou Normal University, Hangzhou 311121, China.; Collaborative Innovation Center of Traditional Chinese Medicines of Zhejiang Province, Hangzhou Normal University, Hangzhou 311121, China.
Xie T; College of Pharmacy, Hangzhou Normal University, Hangzhou 311121, China.; Key Laboratory of Elemene Class Anti-Cancer Chinese Medicines, Hangzhou Normal University, Hangzhou 311121, China.; Engineering Laboratory of Development and Application of Traditional Chinese Medicines, Hangzhou Normal University, Hangzhou 311121, China.; Collaborative Innovation Center of Traditional Chinese Medicines of Zhejiang Province, Hangzhou Normal University, Hangzhou 311121, China.
Wang S; College of Pharmacy, Hangzhou Normal University, Hangzhou 311121, China.; Key Laboratory of Elemene Class Anti-Cancer Chinese Medicines, Hangzhou Normal University, Hangzhou 311121, China.; Engineering Laboratory of Development and Application of Traditional Chinese Medicines, Hangzhou Normal University, Hangzhou 311121, China.; Collaborative Innovation Center of Traditional Chinese Medicines of Zhejiang Province, Hangzhou Normal University, Hangzhou 311121, China.
Zhang H; College of Pharmacy, Hangzhou Normal University, Hangzhou 311121, China.; Key Laboratory of Elemene Class Anti-Cancer Chinese Medicines, Hangzhou Normal University, Hangzhou 311121, China.; Engineering Laboratory of Development and Application of Traditional Chinese Medicines, Hangzhou Normal University, Hangzhou 311121, China.; Collaborative Innovation Center of Traditional Chinese Medicines of Zhejiang Province, Hangzhou Normal University, Hangzhou 311121, China.
Tian Q; College of Pharmacy, Hangzhou Normal University, Hangzhou 311121, China.; Key Laboratory of Elemene Class Anti-Cancer Chinese Medicines, Hangzhou Normal University, Hangzhou 311121, China.; Engineering Laboratory of Development and Application of Traditional Chinese Medicines, Hangzhou Normal University, Hangzhou 311121, China.; Collaborative Innovation Center of Traditional Chinese Medicines of Zhejiang Province, Hangzhou Normal University, Hangzhou 311121, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Jan 14; Vol. 23 (2). Date of Electronic Publication: 2022 Jan 14.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Biomarkers, Tumor*
Exosomes/*metabolism
Neoplasms/*diagnosis
Neoplasms/*metabolism
Cell-Free Nucleic Acids ; Circulating Tumor DNA ; Disease Susceptibility ; Early Detection of Cancer/methods ; Humans ; Liquid Biopsy/methods ; Molecular Diagnostic Techniques ; Neoplasms/etiology ; Oncogene Proteins ; SELEX Aptamer Technique ; Spectrum Analysis, Raman/methods
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Identification of a Novel Five-Gene Signature as a Prognostic and Diagnostic Biomarker in Colorectal Cancers.
Autorzy:
Ghatak S; Cell and Experimental Pathology, Department of Translational Medicine, Lund University, 205 02 Malmö, Sweden.
Mehrabi SF; Cell and Experimental Pathology, Department of Translational Medicine, Lund University, 205 02 Malmö, Sweden.
Mehdawi LM; Cell and Experimental Pathology, Department of Translational Medicine, Lund University, 205 02 Malmö, Sweden.
Satapathy SR; Cell and Experimental Pathology, Department of Translational Medicine, Lund University, 205 02 Malmö, Sweden.
Sjölander A; Cell and Experimental Pathology, Department of Translational Medicine, Lund University, 205 02 Malmö, Sweden.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Jan 12; Vol. 23 (2). Date of Electronic Publication: 2022 Jan 12.
Typ publikacji:
Journal Article
MeSH Terms:
Biomarkers, Tumor*
Gene Expression Regulation, Neoplastic*
Colorectal Neoplasms/*diagnosis
Colorectal Neoplasms/*genetics
Colorectal Neoplasms/*mortality
Databases, Genetic ; Gene Expression Profiling ; Humans ; Immunohistochemistry ; Kaplan-Meier Estimate ; Molecular Diagnostic Techniques ; Prognosis ; Proportional Hazards Models ; ROC Curve ; Transcriptome
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Circular RNAs in acute myeloid leukemia.
Autorzy:
Singh V; Department of Oncology, Karmanos Cancer Institute/Wayne State University, 4100 John R, HWCRC 740.2, Detroit, MI, 48201, USA.
Uddin MH; Department of Oncology, Wayne State University School of Medicine, 4100 John R, HWCRC 732, Detroit, MI, 48201, USA.
Zonder JA; Department of Oncology, Karmanos Cancer Institute/Wayne State University, 4100 John R, HWCRC 740.2, Detroit, MI, 48201, USA.
Azmi AS; Department of Oncology, Wayne State University School of Medicine, 4100 John R, HWCRC 732, Detroit, MI, 48201, USA.
Balasubramanian SK; Department of Oncology, Karmanos Cancer Institute/Wayne State University, 4100 John R, HWCRC 740.2, Detroit, MI, 48201, USA. .
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Źródło:
Molecular cancer [Mol Cancer] 2021 Nov 18; Vol. 20 (1), pp. 149. Date of Electronic Publication: 2021 Nov 18.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Biomarkers, Tumor*
Gene Expression Regulation, Leukemic*
RNA, Circular*
Leukemia, Myeloid, Acute/*genetics
Animals ; Disease Management ; Disease Susceptibility ; Drug Resistance, Neoplasm/genetics ; Humans ; Leukemia, Myeloid, Acute/diagnosis ; Leukemia, Myeloid, Acute/metabolism ; Leukemia, Myeloid, Acute/therapy ; Molecular Diagnostic Techniques ; Neoplasm Grading ; Neoplasm Staging ; Prognosis ; RNA Interference ; RNA, Messenger/genetics ; RNA, Untranslated ; Signal Transduction
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Role of oncogenic KRAS in the prognosis, diagnosis and treatment of colorectal cancer.
Autorzy:
Zhu G; Department of Abdominal Oncology, Cancer Center and Laboratory of Molecular Targeted Therapy in Oncology, West China Hospital, Sichuan University, No.37 guoxue lane, Chengdu, 610041, Sichuan Province, China.
Pei L; The State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan Province, China.
Xia H; Department of Abdominal Oncology, Cancer Center and Laboratory of Molecular Targeted Therapy in Oncology, West China Hospital, Sichuan University, No.37 guoxue lane, Chengdu, 610041, Sichuan Province, China.
Tang Q; Department of Abdominal Oncology, Cancer Center and Laboratory of Molecular Targeted Therapy in Oncology, West China Hospital, Sichuan University, No.37 guoxue lane, Chengdu, 610041, Sichuan Province, China.
Bi F; Department of Abdominal Oncology, Cancer Center and Laboratory of Molecular Targeted Therapy in Oncology, West China Hospital, Sichuan University, No.37 guoxue lane, Chengdu, 610041, Sichuan Province, China. .
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Źródło:
Molecular cancer [Mol Cancer] 2021 Nov 06; Vol. 20 (1), pp. 143. Date of Electronic Publication: 2021 Nov 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Biomarkers, Tumor*
Oncogenes*
Colorectal Neoplasms/*diagnosis
Colorectal Neoplasms/*genetics
Colorectal Neoplasms/*therapy
Proto-Oncogene Proteins p21(ras)/*genetics
Colorectal Neoplasms/metabolism ; Combined Modality Therapy/adverse effects ; Combined Modality Therapy/methods ; Disease Management ; Disease Susceptibility ; Drug Development ; Gene Expression Regulation, Neoplastic ; Humans ; Liquid Biopsy/methods ; Liquid Biopsy/standards ; Molecular Diagnostic Techniques ; Molecular Targeted Therapy ; Mutation ; Prognosis ; Proto-Oncogene Proteins p21(ras)/chemistry ; Proto-Oncogene Proteins p21(ras)/metabolism ; Sensitivity and Specificity ; Signal Transduction ; Structure-Activity Relationship ; Treatment Outcome
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Applicability of the adjusted graded prognostic assessment for lung cancer with brain metastases using molecular markers (Lung-molGPA) in a Chinese cohort: A retrospective study of multiple institutions.
Autorzy:
Zhang T; Department of Thoracic Oncology, Cancer Centre, Sichuan University West China Hospital, Chengdu, Sichuan, P.R. China.; Department of Thoracic Oncology, Zunyi Medical University NO.2 Affiliated Hospital, Zunyi, Guizhou, P.R. China.
Zhang Y; Department of Oncology, Guizhou Provincial People's Hospital, Guiyang, Guizhou, P.R. China.
Zhou L; Department of Thoracic Oncology, Cancer Centre, Sichuan University West China Hospital, Chengdu, Sichuan, P.R. China.
Deng S; Department of Thoracic Oncology, Zunyi Medical University NO.2 Affiliated Hospital, Zunyi, Guizhou, P.R. China.
Huang M; Department of Thoracic Oncology, Cancer Centre, Sichuan University West China Hospital, Chengdu, Sichuan, P.R. China.
Liu Y; Department of Oncology, Guizhou Provincial People's Hospital, Guiyang, Guizhou, P.R. China.
Liu Y; Department of Thoracic Oncology, Cancer Centre, Sichuan University West China Hospital, Chengdu, Sichuan, P.R. China.
Gong Y; Department of Thoracic Oncology, Cancer Centre, Sichuan University West China Hospital, Chengdu, Sichuan, P.R. China.
Zhu J; Department of Thoracic Oncology, Cancer Centre, Sichuan University West China Hospital, Chengdu, Sichuan, P.R. China.
Xue J; Department of Thoracic Oncology, Cancer Centre, Sichuan University West China Hospital, Chengdu, Sichuan, P.R. China.
Bai Y; Department of Thoracic Oncology, Zunyi Medical University NO.2 Affiliated Hospital, Zunyi, Guizhou, P.R. China.
Ma H; Department of Thoracic Oncology, Zunyi Medical University NO.2 Affiliated Hospital, Zunyi, Guizhou, P.R. China.
Zhang Y; Department of Thoracic Oncology, Cancer Centre, Sichuan University West China Hospital, Chengdu, Sichuan, P.R. China.
Yu M; Department of Thoracic Oncology, Cancer Centre, Sichuan University West China Hospital, Chengdu, Sichuan, P.R. China.
Li Y; Department of Thoracic Oncology, Cancer Centre, Sichuan University West China Hospital, Chengdu, Sichuan, P.R. China.
Wang Y; Department of Thoracic Oncology, Cancer Centre, Sichuan University West China Hospital, Chengdu, Sichuan, P.R. China.
Zou B; Department of Thoracic Oncology, Cancer Centre, Sichuan University West China Hospital, Chengdu, Sichuan, P.R. China.
Zhou X; Department of Thoracic Oncology, Cancer Centre, Sichuan University West China Hospital, Chengdu, Sichuan, P.R. China.
Xiu W; Department of Thoracic Oncology, Cancer Centre, Sichuan University West China Hospital, Chengdu, Sichuan, P.R. China.
Na F; Department of Thoracic Oncology, Cancer Centre, Sichuan University West China Hospital, Chengdu, Sichuan, P.R. China.
Xu Y; Department of Thoracic Oncology, Cancer Centre, Sichuan University West China Hospital, Chengdu, Sichuan, P.R. China.
Peng F; Department of Thoracic Oncology, Cancer Centre, Sichuan University West China Hospital, Chengdu, Sichuan, P.R. China.
Wang J; Department of Thoracic Oncology, Cancer Centre, Sichuan University West China Hospital, Chengdu, Sichuan, P.R. China.
Lu Y; Department of Thoracic Oncology, Cancer Centre, Sichuan University West China Hospital, Chengdu, Sichuan, P.R. China.
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Źródło:
Cancer medicine [Cancer Med] 2020 Dec; Vol. 9 (23), pp. 8772-8781. Date of Electronic Publication: 2020 Oct 07.
Typ publikacji:
Comparative Study; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
MeSH Terms:
Molecular Diagnostic Techniques*
Adenocarcinoma of Lung/*genetics
Anaplastic Lymphoma Kinase/*genetics
Biomarkers, Tumor/*genetics
Brain Neoplasms/*genetics
Carcinoma, Non-Small-Cell Lung/*genetics
Lung Neoplasms/*genetics
Adenocarcinoma of Lung/mortality ; Adenocarcinoma of Lung/secondary ; Brain Neoplasms/mortality ; Brain Neoplasms/secondary ; Carcinoma, Non-Small-Cell Lung/mortality ; Carcinoma, Non-Small-Cell Lung/secondary ; China ; ErbB Receptors/genetics ; Female ; Humans ; Lung Neoplasms/mortality ; Lung Neoplasms/pathology ; Male ; Middle Aged ; Neoplasm Staging ; Predictive Value of Tests ; Retrospective Studies ; Risk Assessment ; Risk Factors ; Time Factors
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Dual-modality loop-mediated isothermal amplification for pretreatment-free detection of Septin9 methylated DNA in colorectal cancer.
Autorzy:
Lin Q; Department of Chemistry, Fudan University, Shanghai, 200438, People's Republic of China.
Fang X; Department of Chemistry, Fudan University, Shanghai, 200438, People's Republic of China.
Chen H; Department of Chemistry, Fudan University, Shanghai, 200438, People's Republic of China. .
Weng W; Department of Clinical Laboratory, Yangpu Hospital, Tongji University School of Medicine, Shanghai, 200090, China. .
Liu B; Department of Chemistry, Fudan University, Shanghai, 200438, People's Republic of China.; Shanghai Stomatological Hospital, Shanghai, 200438, People's Republic of China.
Kong J; Department of Chemistry, Fudan University, Shanghai, 200438, People's Republic of China. .
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Źródło:
Mikrochimica acta [Mikrochim Acta] 2021 Aug 27; Vol. 188 (9), pp. 307. Date of Electronic Publication: 2021 Aug 27.
Typ publikacji:
Journal Article
MeSH Terms:
DNA Methylation*
Biomarkers, Tumor/*blood
Colorectal Neoplasms/*diagnosis
DNA/*blood
Septins/*genetics
Biomarkers, Tumor/chemistry ; Cell Line, Tumor ; Colorectal Neoplasms/blood ; Colorimetry ; DNA/chemistry ; Fluorescent Dyes/chemistry ; Humans ; Molecular Diagnostic Techniques ; Nucleic Acid Amplification Techniques ; Organic Chemicals/chemistry ; Spectrometry, Fluorescence
SCR Protocol:
LAMP assay
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Prospective high-throughput genome profiling of advanced cancers: results of the PERMED-01 clinical trial.
Autorzy:
Bertucci F; Laboratory of Predictive Oncology, Department of Medical Oncology, Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725, Aix-Marseille University, 232 Boulevard Sainte-Marguerite, 13009, Marseille, France. .; Department of Medical Oncology, Institut Paoli-Calmettes, Marseille, France. .
Gonçalves A; Laboratory of Predictive Oncology, Department of Medical Oncology, Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725, Aix-Marseille University, 232 Boulevard Sainte-Marguerite, 13009, Marseille, France.; Department of Medical Oncology, Institut Paoli-Calmettes, Marseille, France.
Guille A; Laboratory of Predictive Oncology, Department of Medical Oncology, Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725, Aix-Marseille University, 232 Boulevard Sainte-Marguerite, 13009, Marseille, France.
Adelaïde J; Laboratory of Predictive Oncology, Department of Medical Oncology, Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725, Aix-Marseille University, 232 Boulevard Sainte-Marguerite, 13009, Marseille, France.
Garnier S; Laboratory of Predictive Oncology, Department of Medical Oncology, Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725, Aix-Marseille University, 232 Boulevard Sainte-Marguerite, 13009, Marseille, France.
Carbuccia N; Laboratory of Predictive Oncology, Department of Medical Oncology, Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725, Aix-Marseille University, 232 Boulevard Sainte-Marguerite, 13009, Marseille, France.
Billon E; Department of Medical Oncology, Institut Paoli-Calmettes, Marseille, France.
Finetti P; Laboratory of Predictive Oncology, Department of Medical Oncology, Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725, Aix-Marseille University, 232 Boulevard Sainte-Marguerite, 13009, Marseille, France.
Sfumato P; Biostatistics Unit, Institut Paoli-Calmettes, Marseille, France.
Monneur A; Department of Medical Oncology, Institut Paoli-Calmettes, Marseille, France.
Pécheux C; Department of Medical genetics, Hôpital Timone Enfants, AP-HM, Marseille, France.
Khran M; Department of Medical genetics, Hôpital Timone Enfants, AP-HM, Marseille, France.; Aix-Marseille University, Inserm, U1251-MMG, Marseille Medical Genetics, Marseille, France.
Brunelle S; Department of Imaging, Institut Paoli-Calmettes, Marseille, France.
Mescam L; Department of Biopathology, Institut Paoli-Calmettes, Marseille, France.
Thomassin-Piana J; Department of Biopathology, Institut Paoli-Calmettes, Marseille, France.
Poizat F; Department of Biopathology, Institut Paoli-Calmettes, Marseille, France.
Charafe-Jauffret E; Department of Biopathology, Institut Paoli-Calmettes, Marseille, France.
Turrini O; Department of Surgical Oncology, Institut Paoli-Calmettes, Marseille, France.
Lambaudie E; Department of Surgical Oncology, Institut Paoli-Calmettes, Marseille, France.
Provansal M; Department of Medical Oncology, Institut Paoli-Calmettes, Marseille, France.
Extra JM; Department of Medical Oncology, Institut Paoli-Calmettes, Marseille, France.
Madroszyk A; Department of Medical Oncology, Institut Paoli-Calmettes, Marseille, France.
Gilabert M; Department of Medical Oncology, Institut Paoli-Calmettes, Marseille, France.
Sabatier R; Department of Medical Oncology, Institut Paoli-Calmettes, Marseille, France.
Vicier C; Department of Medical Oncology, Institut Paoli-Calmettes, Marseille, France.
Mamessier E; Laboratory of Predictive Oncology, Department of Medical Oncology, Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725, Aix-Marseille University, 232 Boulevard Sainte-Marguerite, 13009, Marseille, France.
Chabannon C; Biobank, Department of Hematology, Institut Paoli-Calmettes, Marseille, France.
Pakradouni J; Department of Clinical Research and Innovation, Institut Paoli-Calmettes, Marseille, France.
Viens P; Department of Medical Oncology, Institut Paoli-Calmettes, Marseille, France.
André F; Department of Medical Oncology, Gustave Roussy Cancer Campus, UMR981 Inserm, Villejuif, France.; Paris Sud University, Orsay, France.
Gravis G; Department of Medical Oncology, Institut Paoli-Calmettes, Marseille, France.
Popovici C; Department of Oncogenetics, Institut Paoli-Calmettes, Marseille, France.
Birnbaum D; Laboratory of Predictive Oncology, Department of Medical Oncology, Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725, Aix-Marseille University, 232 Boulevard Sainte-Marguerite, 13009, Marseille, France.
Chaffanet M; Laboratory of Predictive Oncology, Department of Medical Oncology, Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725, Aix-Marseille University, 232 Boulevard Sainte-Marguerite, 13009, Marseille, France.
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Źródło:
Genome medicine [Genome Med] 2021 May 18; Vol. 13 (1), pp. 87. Date of Electronic Publication: 2021 May 18.
Typ publikacji:
Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Biomarkers, Tumor*
Genomics*/methods
High-Throughput Nucleotide Sequencing*
Neoplasms/*diagnosis
Neoplasms/*genetics
Adult ; Aged ; Aged, 80 and over ; Biopsy ; Combined Modality Therapy ; Comparative Genomic Hybridization ; Disease Management ; Disease Susceptibility ; Female ; Genetic Variation ; Humans ; Male ; Middle Aged ; Molecular Diagnostic Techniques/methods ; Molecular Diagnostic Techniques/standards ; Neoplasm Grading ; Neoplasm Staging ; Neoplasms/mortality ; Neoplasms/therapy ; Precision Medicine/methods ; Prognosis ; Prospective Studies ; Treatment Outcome ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Multi-site tumor sampling highlights molecular intra-tumor heterogeneity in malignant pleural mesothelioma.
Autorzy:
Meiller C; Centre de Recherche des Cordeliers, Inserm UMRS-1138, Sorbonne Université, Université de Paris, Functional Genomics of Solid Tumors, Paris, France.
Montagne F; Centre de Recherche des Cordeliers, Inserm UMRS-1138, Sorbonne Université, Université de Paris, Functional Genomics of Solid Tumors, Paris, France.; Present address: Service de Chirurgie Thoracique, Hôpital Calmette, CHRU de Lille, Lille, France.
Hirsch TZ; Centre de Recherche des Cordeliers, Inserm UMRS-1138, Sorbonne Université, Université de Paris, Functional Genomics of Solid Tumors, Paris, France.
Caruso S; Centre de Recherche des Cordeliers, Inserm UMRS-1138, Sorbonne Université, Université de Paris, Functional Genomics of Solid Tumors, Paris, France.
de Wolf J; Centre de Recherche des Cordeliers, Inserm UMRS-1138, Sorbonne Université, Université de Paris, Functional Genomics of Solid Tumors, Paris, France.; Present address: Service de Chirurgie Thoracique et Transplantation Pulmonaire, Hôpital Foch, Suresnes, France.
Bayard Q; Centre de Recherche des Cordeliers, Inserm UMRS-1138, Sorbonne Université, Université de Paris, Functional Genomics of Solid Tumors, Paris, France.
Assié JB; Centre de Recherche des Cordeliers, Inserm UMRS-1138, Sorbonne Université, Université de Paris, Functional Genomics of Solid Tumors, Paris, France.; University Paris-Est Créteil (UPEC), CEpiA (Clinical Epidemiology and Ageing), EA 7376- IMRB, UPEC, Créteil, France.; GRC OncoThoParisEst, Service de Pneumologie, CHI Créteil, UPEC, Créteil, France.
Meunier L; Centre de Recherche des Cordeliers, Inserm UMRS-1138, Sorbonne Université, Université de Paris, Functional Genomics of Solid Tumors, Paris, France.
Blum Y; Programme Cartes d'Identité des Tumeurs (CIT), Ligue Nationale Contre Le Cancer, Paris, France.; Present address: IGDR UMR 6290, CNRS, Université de Rennes 1, Rennes, France.
Quetel L; Centre de Recherche des Cordeliers, Inserm UMRS-1138, Sorbonne Université, Université de Paris, Functional Genomics of Solid Tumors, Paris, France.
Gibault L; Assistance Publique-Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Paris, France.; Service d'Anatomopathologie et Cytologie, Université de Paris, Hôpital Européen Georges Pompidou, Paris, France.
Pintilie E; Univ. Lille, CHU Lille, Service de Chirurgie Thoracique, Hôpital Calmette, Lille, France.
Badoual C; Assistance Publique-Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Paris, France.; Service d'Anatomopathologie et Cytologie, Université de Paris, Hôpital Européen Georges Pompidou, Paris, France.
Humez S; Univ. Lille, CHU Lille, Institut de Pathologie, Lille, France.; Univ. Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, UMR9020 - UMR1277 - Canther - Cancer Heterogeneity, Plasticity and Resistance to Therapies, Lille, France.
Galateau-Sallé F; Centre National Référent MESOPATH, Centre Leon Berard, Lyon, France.
Copin MC; Univ. Lille, CHU Lille, Institut de Pathologie, Lille, France.; Present address: Département de Pathologie Cellulaire et Tissulaire, CHU d'Angers, Angers, France.
Letouzé E; Centre de Recherche des Cordeliers, Inserm UMRS-1138, Sorbonne Université, Université de Paris, Functional Genomics of Solid Tumors, Paris, France.
Scherpereel A; Univ. Lille, CHU Lille, Service de Pneumologie et d'Oncologie Thoracique, unité INSERM 1189 OncoThAI, Lille, France.; Réseau National Expert pour le Mésothéliome Pleural Malin (NETMESO), Lille, France.
Zucman-Rossi J; Centre de Recherche des Cordeliers, Inserm UMRS-1138, Sorbonne Université, Université de Paris, Functional Genomics of Solid Tumors, Paris, France.; Assistance Publique-Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Paris, France.
Le Pimpec-Barthes F; Centre de Recherche des Cordeliers, Inserm UMRS-1138, Sorbonne Université, Université de Paris, Functional Genomics of Solid Tumors, Paris, France.; Assistance Publique-Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Paris, France.; Service de Chirurgie Thoracique, Hôpital Européen Georges Pompidou, Paris, France.
Jaurand MC; Centre de Recherche des Cordeliers, Inserm UMRS-1138, Sorbonne Université, Université de Paris, Functional Genomics of Solid Tumors, Paris, France.
Jean D; Centre de Recherche des Cordeliers, Inserm UMRS-1138, Sorbonne Université, Université de Paris, Functional Genomics of Solid Tumors, Paris, France. .
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Źródło:
Genome medicine [Genome Med] 2021 Jul 14; Vol. 13 (1), pp. 113. Date of Electronic Publication: 2021 Jul 14.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Biomarkers, Tumor*
Mesothelioma, Malignant/*etiology
Pleural Neoplasms/*etiology
Biopsy ; Computational Biology/methods ; DNA Mutational Analysis/methods ; Disease Management ; Disease Susceptibility ; Gene Expression Profiling ; Genetic Heterogeneity ; High-Throughput Nucleotide Sequencing ; Humans ; Mesothelioma, Malignant/diagnosis ; Mesothelioma, Malignant/metabolism ; Molecular Diagnostic Techniques ; Molecular Sequence Annotation ; Mutation ; Pleural Neoplasms/diagnosis ; Pleural Neoplasms/metabolism ; Precision Medicine/methods ; Precision Medicine/standards ; Prognosis ; Tumor Microenvironment/genetics ; Exome Sequencing
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Could MicroRNAs Be Useful Tools to Improve the Diagnosis and Treatment of Rare Gynecological Cancers? A Brief Overview.
Autorzy:
Di Fiore R; Department of Anatomy, Faculty of Medicine and Surgery, University of Malta, MSD 2080 Msida, Malta.; Center for Biotechnology, Sbarro Institute for Cancer Research and Molecular Medicine, College of Science and Technology, Temple University, Philadelphia, PA 19122, USA.
Suleiman S; Department of Anatomy, Faculty of Medicine and Surgery, University of Malta, MSD 2080 Msida, Malta.
Pentimalli F; Cell Biology and Biotherapy Unit, Istituto Nazionale Tumori-IRCCS-Fondazione G. Pascale, I-80131 Napoli, Italy.
O'Toole SA; Departments of Obstetrics and Gynaecology and Histopathology, Trinity St James's Cancer Institute, Trinity College Dublin, 8 Dublin, Ireland.
O'Leary JJ; Department of Histopathology, Trinity St James's Cancer Institute, Trinity College Dublin, 8 Dublin, Ireland.
Ward MP; Department of Histopathology, Trinity St James's Cancer Institute, Trinity College Dublin, 8 Dublin, Ireland.
Conlon NT; National Institute for Cellular Biotechnology, Dublin City University, Glasnevin, 9 Dublin, Ireland.
Sabol M; Laboratory for Hereditary Cancer, Division of Molecular Medicine, Ruđer Bošković Institute, 10000 Zagreb, Croatia.
Ozretić P; Laboratory for Hereditary Cancer, Division of Molecular Medicine, Ruđer Bošković Institute, 10000 Zagreb, Croatia.
Erson-Bensan AE; Department of Biological Sciences, Middle East Technical University, Ankara 06810, Turkey.
Reed N; Beatson Oncology Centre, Gartnavel General Hospital, 1053 Great Western Road, Glasgow G12 0YN, UK.
Giordano A; Center for Biotechnology, Sbarro Institute for Cancer Research and Molecular Medicine, College of Science and Technology, Temple University, Philadelphia, PA 19122, USA.; Department of Medical Biotechnologies, University of Siena, 53100 Siena, Italy.
Herrington CS; Cancer Research UK Edinburgh Centre, Western General Hospital, University of Edinburgh, Crewe Road South, Edinburgh EH4 2XR, UK.
Calleja-Agius J; Department of Anatomy, Faculty of Medicine and Surgery, University of Malta, MSD 2080 Msida, Malta.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Apr 07; Vol. 22 (8). Date of Electronic Publication: 2021 Apr 07.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Biomarkers, Tumor*
Genital Neoplasms, Female/*diagnosis
Genital Neoplasms, Female/*genetics
MicroRNAs/*genetics
Circulating MicroRNA ; Clinical Decision-Making ; Disease Management ; Female ; Gene Expression Regulation, Neoplastic ; Genital Neoplasms, Female/therapy ; Humans ; Molecular Diagnostic Techniques/methods ; Molecular Diagnostic Techniques/standards ; Pregnancy ; Prognosis ; RNA Interference ; RNA, Messenger ; Treatment Outcome
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The role of mRNA in the development, diagnosis, treatment and prognosis of neural tumors.
Autorzy:
Zheng Y; Department of Anesthesiology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, People's Republic of China.; School & Hospital of Stomatology, Wenzhou Medical University, Wenzhou, 325000, People's Republic of China.
Luo Y; Department of Anesthesiology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, People's Republic of China.
Chen X; Department of Anesthesiology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, People's Republic of China.
Li H; Department of Anesthesiology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, People's Republic of China.
Huang B; Department of Anesthesiology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, People's Republic of China.
Zhou B; Department of Anesthesiology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, People's Republic of China.
Zhu L; Department of clinical laboratory, Wenzhou Medical University, Wenzhou, 325000, People's Republic of China. .
Kang X; Department of Anesthesiology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China. .
Geng W; Department of Anesthesiology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, People's Republic of China. .
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Źródło:
Molecular cancer [Mol Cancer] 2021 Mar 05; Vol. 20 (1), pp. 49. Date of Electronic Publication: 2021 Mar 05.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Biomarkers, Tumor*
Cell Transformation, Neoplastic/*genetics
Nervous System Neoplasms/*diagnosis
Nervous System Neoplasms/*genetics
Nervous System Neoplasms/*therapy
RNA, Messenger/*genetics
Animals ; Cancer Vaccines ; Cell Transformation, Neoplastic/metabolism ; Combined Modality Therapy ; Diagnosis, Differential ; Disease Management ; Disease Susceptibility ; Epigenesis, Genetic ; Exosomes/metabolism ; Gene Expression Regulation, Neoplastic ; Humans ; Molecular Diagnostic Techniques ; Nervous System Neoplasms/mortality ; Organ Specificity/genetics ; Prognosis ; RNA Transport ; RNA, Messenger/immunology ; RNA, Messenger/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Gynecological Sarcomas: Molecular Characteristics, Behavior, and Histology-Driven Therapy.
Autorzy:
Libertini M; Royal Marsden Hospital/Institute of Cancer Research, London, UK.
Hallin M; Royal Marsden Hospital/Institute of Cancer Research, London, UK.
Thway K; Royal Marsden Hospital/Institute of Cancer Research, London, UK.
Noujaim J; Maisonneuve-Rosemont Hospital, Montreal, Canada.
Benson C; Royal Marsden Hospital/Institute of Cancer Research, London, UK.
van der Graaf W; Royal Marsden Hospital/Institute of Cancer Research, London, UK.
Jones RL; Royal Marsden Hospital/Institute of Cancer Research, London, UK.
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Źródło:
International journal of surgical pathology [Int J Surg Pathol] 2021 Feb; Vol. 29 (1), pp. 4-20. Date of Electronic Publication: 2020 Sep 10.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Biomarkers, Tumor/*analysis
Chemoradiotherapy, Adjuvant/*methods
Genital Neoplasms, Female/*diagnosis
Gynecologic Surgical Procedures/*methods
Sarcoma/*diagnosis
Female ; Genital Neoplasms, Female/mortality ; Genital Neoplasms, Female/pathology ; Genital Neoplasms, Female/therapy ; Humans ; Immunohistochemistry ; Molecular Diagnostic Techniques ; Neoplasm Grading ; Ovary/pathology ; Progression-Free Survival ; Sarcoma/mortality ; Sarcoma/pathology ; Sarcoma/therapy ; Uterus/pathology ; Vagina/pathology ; Vulva/pathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Digital PCR in Myeloid Malignancies: Ready to Replace Quantitative PCR?
Autorzy:
Cilloni D; Department of Clinical and Biological Sciences, University of Turin, 10043 Turin, Italy. .
Petiti J; Department of Clinical and Biological Sciences, University of Turin, 10043 Turin, Italy. .
Rosso V; Department of Clinical and Biological Sciences, University of Turin, 10043 Turin, Italy. .
Andreani G; Department of Clinical and Biological Sciences, University of Turin, 10043 Turin, Italy. .
Dragani M; Department of Clinical and Biological Sciences, University of Turin, 10043 Turin, Italy. .
Fava C; Department of Clinical and Biological Sciences, University of Turin, 10043 Turin, Italy. .
Saglio G; Department of Clinical and Biological Sciences, University of Turin, 10043 Turin, Italy. .
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2019 May 07; Vol. 20 (9). Date of Electronic Publication: 2019 May 07.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Biomarkers, Tumor/*genetics
Leukemia, Myeloid, Acute/*diagnosis
Molecular Diagnostic Techniques/*methods
Polymerase Chain Reaction/*methods
Humans ; Leukemia, Myeloid, Acute/therapy ; Molecular Diagnostic Techniques/standards ; Polymerase Chain Reaction/standards
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Measurements Methods for the Development of MicroRNA-Based Tests for Cancer Diagnosis.
Autorzy:
Precazzini F; Dipartimento di Biologia Cellulare, Computazionale e Integrata (CIBIO), Università degli Studi di Trento, Via Sommarive 9, 38123 Trento, Italy.
Detassis S; OPTOI Srl, Via Vienna 8, 38121 Trento, Italy.
Imperatori AS; Dipartimento di Medicina e Chirurgia (DMC), Università degli Studi dell'Insubria, Via Guicciardini 9, 21100 Varese, Italy.
Denti MA; Dipartimento di Biologia Cellulare, Computazionale e Integrata (CIBIO), Università degli Studi di Trento, Via Sommarive 9, 38123 Trento, Italy.
Campomenosi P; Dipartimento di Biotecnologie e Scienze della Vita (DBSV), Università degli Studi dell'Insubria, Via Dunant 3, 21100 Varese, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Jan 25; Vol. 22 (3). Date of Electronic Publication: 2021 Jan 25.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Biomarkers, Tumor*
Genetic Testing/*methods
MicroRNAs/*genetics
Neoplasms/*diagnosis
Neoplasms/*genetics
Cell-Free Nucleic Acids ; Circulating MicroRNA ; Gene Expression Regulation, Neoplastic ; Genetic Testing/standards ; Humans ; Liquid Biopsy/methods ; Molecular Diagnostic Techniques/methods ; Molecular Diagnostic Techniques/standards ; Prognosis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
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