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Wyszukujesz frazę ""Molecular Medicine"" wg kryterium: Temat


Tytuł :
Evaluation of a saliva molecular point of care for the detection of SARS-CoV-2 in ambulatory care.
Autorzy :
LeGoff J; Virologie, AP-HP, Hôpital Saint Louis, 1 Avenue Claude Vellefaux, 75010, Paris, France. .; INSERM, Equipe INSIGHT, U976, 75010, Université de Paris, Paris, France. .
Kernéis S; INSERM, IAME, Université de Paris, 75018, Paris, France.; Equipe de Prévention du Risque Infectieux, AP-HP, Hôpital Bichat, 75018, Paris, France.; Institut Pasteur, Epidemiology and Modelling of Antibiotic Evasion, 75015, Paris, France.
Elie C; Clinical Research Unit / Clinical Investigation Center, APHP, Necker-Enfants Malades Hospital, 75015, Paris, France.; EA 7323 Pharmacologie et Thérapeutique de l'enfant et de la Femme Enceinte, Université de Paris, 75015, Paris, France.
Mercier-Delarue S; Virologie, AP-HP, Hôpital Saint Louis, 1 Avenue Claude Vellefaux, 75010, Paris, France.
Gastli N; Plateforme Covid IDF, AP-HP Centre, 75014, Paris, France.
Choupeaux L; Clinical Research Unit / Clinical Investigation Center, APHP, Necker-Enfants Malades Hospital, 75015, Paris, France.
Fourgeaud J; Virologie, AP-HP, Hôpital Necker-Enfants Malades, 75015, Paris, France.
Alby ML; Centre de Dépistage COVISAN 13 14 15, Communauté Professionnelle de Territoire de Santé, 75014, Paris, France.
Quentin P; Centre de Dépistage COVISAN 13 14 15, Communauté Professionnelle de Territoire de Santé, 75014, Paris, France.
Pavie J; Immuno-Infectiologie, AP-HP, Hôtel Dieu, 75004, Paris, France.; Centre de Dépistage COVISAN, AP-HP, Hôtel-Dieu, 75004, Paris, France.
Brazille P; Immuno-Infectiologie, AP-HP, Hôtel Dieu, 75004, Paris, France.; Centre de Dépistage COVISAN, AP-HP, Hôtel-Dieu, 75004, Paris, France.
Néré ML; Virologie, AP-HP, Hôpital Saint Louis, 1 Avenue Claude Vellefaux, 75010, Paris, France.
Minier M; Virologie, AP-HP, Hôpital Saint Louis, 1 Avenue Claude Vellefaux, 75010, Paris, France.
Gabassi A; Virologie, AP-HP, Hôpital Saint Louis, 1 Avenue Claude Vellefaux, 75010, Paris, France.
Leroy C; Plateforme Covid IDF, AP-HP Centre, 75014, Paris, France.; Plateforme SeqOIA, AP-HP, 75014, Paris, France.
Parfait B; Centre de Ressources Biologiques, Hôpital Cochin, 75014, Paris, France.
Tréluyer JM; Clinical Research Unit / Clinical Investigation Center, APHP, Necker-Enfants Malades Hospital, 75015, Paris, France.; EA 7323 Pharmacologie et Thérapeutique de l'enfant et de la Femme Enceinte, Université de Paris, 75015, Paris, France.
Delaugerre C; Virologie, AP-HP, Hôpital Saint Louis, 1 Avenue Claude Vellefaux, 75010, Paris, France.; INSERM, U944, 75010, Université de Paris, Paris, France.
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Źródło :
Scientific reports [Sci Rep] 2021 Oct 26; Vol. 11 (1), pp. 21126. Date of Electronic Publication: 2021 Oct 26.
Typ publikacji :
Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
SARS-CoV-2*
Ambulatory Care/*methods
COVID-19/*diagnosis
COVID-19/*metabolism
COVID-19 Nucleic Acid Testing/*methods
Saliva/*metabolism
Adult ; Diagnostic Tests, Routine ; False Negative Reactions ; False Positive Reactions ; Female ; Humans ; Male ; Middle Aged ; Molecular Diagnostic Techniques ; Molecular Medicine ; Nasopharynx/virology ; Nucleic Acid Amplification Techniques ; Point-of-Care Systems ; Point-of-Care Testing ; Prospective Studies ; RNA, Viral/genetics ; Real-Time Polymerase Chain Reaction ; Reproducibility of Results ; Sensitivity and Specificity
SCR Protocol :
LAMP assay
Czasopismo naukowe
Tytuł :
Prediction of severe adverse events, modes of action and drug treatments for COVID-19's complications.
Autorzy :
Astore C; Center for the Study of Systems Biology, School of Biological Sciences, Georgia Institute of Technology, 950 Atlantic Drive, N.W., Atlanta, GA, 30332, USA.
Zhou H; Center for the Study of Systems Biology, School of Biological Sciences, Georgia Institute of Technology, 950 Atlantic Drive, N.W., Atlanta, GA, 30332, USA.
Jacob J; Emory Vaccine Center, Emory University, Atlanta, GA, 30329, USA.; Yerkes National Primate Research Center, Emory University, Atlanta, GA, 30329, USA.; Department of Microbiology and Immunology, Emory Vaccine Center, School of Medicine, Emory University, Atlanta, GA, 30329, USA.
Skolnick J; Center for the Study of Systems Biology, School of Biological Sciences, Georgia Institute of Technology, 950 Atlantic Drive, N.W., Atlanta, GA, 30332, USA. .
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Źródło :
Scientific reports [Sci Rep] 2021 Oct 21; Vol. 11 (1), pp. 20864. Date of Electronic Publication: 2021 Oct 21.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Virus Replication*
COVID-19/*complications
COVID-19/*diagnosis
COVID-19/*drug therapy
Computational Biology/*methods
Neoplasms/*complications
Nervous System Diseases/*complications
Thrombosis/*complications
Benchmarking ; Comorbidity ; Computer Simulation ; Cytokine Release Syndrome ; Drug Discovery ; Humans ; Machine Learning ; Molecular Medicine ; Phenotype ; SARS-CoV-2 ; Treatment Outcome
SCR Protocol :
COVID-19 drug treatment
Czasopismo naukowe
Tytuł :
Molecular Genetics involved in Neural Tube Defects: Recent Advances and Future Prospective for Molecular Medicine.
Autorzy :
Mishra PR; Department of Anatomy, AIIMS, Bhubaneswar, Odisha, India.
Barik M; Additional Professor in Department of Anatomy, AIIMS, Bhubaneswar, Dumuduma, Odisha, India.
Mahapatra AK; Department of Anatomy, AIIMS, Bhubaneswar, Odisha, India.
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Źródło :
Neurology India [Neurol India] 2020 Sep-Oct; Vol. 68 (5), pp. 1144-1150.
Typ publikacji :
Journal Article
MeSH Terms :
Molecular Medicine*
Neural Tube Defects*/genetics
Dietary Supplements ; Female ; Folic Acid ; Humans ; India ; Pregnancy
Czasopismo naukowe
Tytuł :
The Changing Face of Nuclear Cardiology: Guiding Cardiovascular Care Toward Molecular Medicine.
Autorzy :
Werner RA; Department of Nuclear Medicine, Hannover Medical School, Hannover, Germany; and.
Thackeray JT; Department of Nuclear Medicine, Hannover Medical School, Hannover, Germany; and.
Diekmann J; Department of Nuclear Medicine, Hannover Medical School, Hannover, Germany; and.
Weiberg D; Department of Nuclear Medicine, Hannover Medical School, Hannover, Germany; and.
Bauersachs J; Department of Cardiology and Angiology, Hannover Medical School, Hannover, Germany.
Bengel FM; Department of Nuclear Medicine, Hannover Medical School, Hannover, Germany; and .
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Źródło :
Journal of nuclear medicine : official publication, Society of Nuclear Medicine [J Nucl Med] 2020 Jul; Vol. 61 (7), pp. 951-961. Date of Electronic Publication: 2020 Apr 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Cardiology*
Molecular Medicine*
Nuclear Medicine*
Cardiovascular Diseases/*diagnostic imaging
Molecular Imaging/*methods
Humans
Czasopismo naukowe
Tytuł :
N-glycan Analysis in Molecular Medicine: Innovator and Biosimilar Protein Therapeutics.
Autorzy :
Borza B; Horvath Csaba Memorial Institute of Bioanalytical Research, Research Institute of Biomolecular and Chemical Engineering, University of Pannonia, Hungary.
Hajba L; Horvath Csaba Memorial Institute of Bioanalytical Research, Research Institute of Biomolecular and Chemical Engineering, University of Pannonia, Hungary.
Guttman A; Horvath Csaba Memorial Institute of Bioanalytical Research, Research Institute of Biomolecular and Chemical Engineering, University of Pannonia, Hungary.
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Źródło :
Current molecular medicine [Curr Mol Med] 2020; Vol. 20 (10), pp. 828-839.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Molecular Medicine*
Biological Therapy/*methods
Biosimilar Pharmaceuticals/*analysis
Polysaccharides/*analysis
Biosimilar Pharmaceuticals/chemistry ; Glycosylation ; Humans ; Polysaccharides/chemistry
Czasopismo naukowe
Tytuł :
Gene therapy matures to medicines.
Autorzy :
Davidson BL; The Raymond G. Perelman Center for Cellular and Molecular Therapeutics, the Children's Hospital of Philadelphia.; The Department of Pathology and Laboratory Medicine Perelman School at the University of Pennsylvania.
Arruda VR; The Raymond G. Perelman Center for Cellular and Molecular Therapeutics, the Children's Hospital of Philadelphia.; The Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA USA.
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Źródło :
Human molecular genetics [Hum Mol Genet] 2019 Oct 01; Vol. 28 (R1), pp. R1-R2.
Typ publikacji :
Editorial
MeSH Terms :
Genetic Therapy*/methods
Genetic Therapy*/trends
Molecular Medicine*/methods
Molecular Medicine*/trends
Humans
Opinia redakcyjna
Tytuł :
Deep learning boosts sensitivity of mass spectrometry-based immunopeptidomics.
Autorzy :
Wilhelm M; Computational Mass Spectrometry, Technical University of Munich (TUM), Freising, Germany. .; Chair of Proteomics and Bioanalytics, Technical University of Munich (TUM), Freising, Germany. .
Zolg DP; Chair of Proteomics and Bioanalytics, Technical University of Munich (TUM), Freising, Germany.
Graber M; Chair of Proteomics and Bioanalytics, Technical University of Munich (TUM), Freising, Germany.
Gessulat S; Chair of Proteomics and Bioanalytics, Technical University of Munich (TUM), Freising, Germany.
Schmidt T; Chair of Proteomics and Bioanalytics, Technical University of Munich (TUM), Freising, Germany.
Schnatbaum K; JPT Peptide Technologies GmbH, Berlin, Germany.
Schwencke-Westphal C; Klinik und Poliklinik für Innere Medizin III, Klinikum rechts der Isar, School of Medicine, Technical University of Munich (TUM), Munich, Germany.; German Cancer Consortium (DKTK), partner site Munich; and German Cancer Research Center (DKFZ), Heidelberg, Germany.; Center for Translational Cancer Research (TranslaTUM), TUM School of Medicine, Technical University of Munich (TUM), Munich, Germany.
Seifert P; Klinik und Poliklinik für Innere Medizin III, Klinikum rechts der Isar, School of Medicine, Technical University of Munich (TUM), Munich, Germany.; Center for Translational Cancer Research (TranslaTUM), TUM School of Medicine, Technical University of Munich (TUM), Munich, Germany.
de Andrade Krätzig N; Center for Translational Cancer Research (TranslaTUM), TUM School of Medicine, Technical University of Munich (TUM), Munich, Germany.; Institute of Molecular Oncology and Functional Genomics, TUM School of Medicine, Technical University of Munich (TUM), Munich, Germany.; Klinik und Poliklinik für Innere Medizin II, Klinikum rechts der Isar, School of Medicine, Technical University of Munich (TUM), Munich, Germany.
Zerweck J; JPT Peptide Technologies GmbH, Berlin, Germany.
Knaute T; JPT Peptide Technologies GmbH, Berlin, Germany.
Bräunlein E; Klinik und Poliklinik für Innere Medizin III, Klinikum rechts der Isar, School of Medicine, Technical University of Munich (TUM), Munich, Germany.; Center for Translational Cancer Research (TranslaTUM), TUM School of Medicine, Technical University of Munich (TUM), Munich, Germany.
Samaras P; Chair of Proteomics and Bioanalytics, Technical University of Munich (TUM), Freising, Germany.
Lautenbacher L; Chair of Proteomics and Bioanalytics, Technical University of Munich (TUM), Freising, Germany.
Klaeger S; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Wenschuh H; JPT Peptide Technologies GmbH, Berlin, Germany.
Rad R; Center for Translational Cancer Research (TranslaTUM), TUM School of Medicine, Technical University of Munich (TUM), Munich, Germany.; Institute of Molecular Oncology and Functional Genomics, TUM School of Medicine, Technical University of Munich (TUM), Munich, Germany.; Klinik und Poliklinik für Innere Medizin II, Klinikum rechts der Isar, School of Medicine, Technical University of Munich (TUM), Munich, Germany.
Delanghe B; Thermo Fisher Scientific, Bremen, Germany.
Huhmer A; Thermo Fisher Scientific, San Jose, CA, USA.
Carr SA; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Clauser KR; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Krackhardt AM; Klinik und Poliklinik für Innere Medizin III, Klinikum rechts der Isar, School of Medicine, Technical University of Munich (TUM), Munich, Germany.; German Cancer Consortium (DKTK), partner site Munich; and German Cancer Research Center (DKFZ), Heidelberg, Germany.; Institute of Molecular Oncology and Functional Genomics, TUM School of Medicine, Technical University of Munich (TUM), Munich, Germany.
Reimer U; JPT Peptide Technologies GmbH, Berlin, Germany.
Kuster B; Chair of Proteomics and Bioanalytics, Technical University of Munich (TUM), Freising, Germany. .; Bavarian Biomolecular Mass Spectrometry Center (BayBioMS), Technical University of Munich (TUM), Freising, Germany. .
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Źródło :
Nature communications [Nat Commun] 2021 Jun 07; Vol. 12 (1), pp. 3346. Date of Electronic Publication: 2021 Jun 07.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Deep Learning*
Peptides/*immunology
Tandem Mass Spectrometry/*methods
Cell Line ; Epitopes ; Extracellular Matrix Proteins/metabolism ; HLA Antigens/immunology ; Histocompatibility Antigens Class I/metabolism ; Histocompatibility Antigens Class II/metabolism ; Humans ; Ligands ; Mass Spectrometry ; Molecular Medicine ; Peptides/metabolism ; Proteomics
Czasopismo naukowe
Tytuł :
Interim and end-treatment F-Fluorocholine PET/CT and bone scan in prostate cancer patients treated with Radium 223 dichloride.
Autorzy :
García Vicente AM; Nuclear Medicine Department, Hospital General Universitario, C/Obispo Rafael Torija S/N, 13005, Ciudad Real, Spain. .
Amo-Salas M; Mathematics Department, Universidad de Castilla-La Mancha, Ciudad Real, Spain.
Cassinello Espinosa J; Oncology Department, Hospital Universitario de Guadalajara, Guadalajara, Spain.
Gómez Díaz R; Oncology Department, Hospital General Universitario, Ciudad Real, Spain.
Soriano Castrejón Á; Nuclear Medicine Department, Hospital General Universitario, C/Obispo Rafael Torija S/N, 13005, Ciudad Real, Spain.
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Źródło :
Scientific reports [Sci Rep] 2021 Apr 01; Vol. 11 (1), pp. 7389. Date of Electronic Publication: 2021 Apr 01.
Typ publikacji :
Journal Article; Multicenter Study
MeSH Terms :
Bone Neoplasms/*diagnostic imaging
Bone and Bones/*diagnostic imaging
Choline/*analogs & derivatives
Positron Emission Tomography Computed Tomography/*methods
Prostatic Neoplasms/*diagnostic imaging
Radium/*chemistry
Aged ; Bone Neoplasms/secondary ; Choline/chemistry ; Disease Progression ; Disease-Free Survival ; Humans ; Male ; Middle Aged ; Molecular Medicine ; Multivariate Analysis ; Proportional Hazards Models ; Prospective Studies ; Radioisotopes/chemistry ; Reproducibility of Results ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Cryptogenic cirrhosis: Old and new perspectives in the era of molecular and genomic medicine.
Autorzy :
Nalbantoglu I; Yale School of Medicine, Department of Anatomic Pathology, 20 York Street EP2-608B, New Haven, CT, USA. Electronic address: .
Jain D; Yale School of Medicine, Department of Anatomic Pathology, 20 York Street EP2-608B, New Haven, CT, USA.
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Źródło :
Seminars in diagnostic pathology [Semin Diagn Pathol] 2019 Nov; Vol. 36 (6), pp. 389-394. Date of Electronic Publication: 2019 Jul 24.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Genomics*
Molecular Medicine*
Liver Cirrhosis/*congenital
Genetic Testing ; High-Throughput Nucleotide Sequencing ; Humans ; Liver Cirrhosis/genetics ; Whole Exome Sequencing
SCR Disease Name :
Cirrhosis, Cryptogenic
Czasopismo naukowe
Tytuł :
Still a place for conventional histopathological analysis in the era of molecular medicine: predicting prognosis of resectable ductal pancreatic adenocarcinoma.
Autorzy :
Fernández Aceñero MJ; Department of Surgical Pathology, Hospital Clínico San Carlos, Avda. Prof. Martín Lagos s/n, 28040, Madrid, Spain. .
Martínez-Useros J; Department of Traslational Oncology, Fundación Jiménez Díaz, Universidad Autónoma de Madrid, Madrid, Spain.
Díez-Valladares L; Surgery (Pancreatobiliary Unit), Hospital Clínico San Carlos, Madrid, Spain.
García-Botella S; Surgery (Pancreatobiliary Unit), Hospital Clínico San Carlos, Madrid, Spain.
Ortega Medina L; Department of Surgical Pathology, Hospital Clínico San Carlos, Avda. Prof. Martín Lagos s/n, 28040, Madrid, Spain.
Pérez Aguirre E; Surgery (Pancreatobiliary Unit), Hospital Clínico San Carlos, Madrid, Spain.
de la Serna Esteban S; Surgery (Pancreatobiliary Unit), Hospital Clínico San Carlos, Madrid, Spain.
Latorre E; Department of Surgical Pathology, Hospital Clínico San Carlos, Avda. Prof. Martín Lagos s/n, 28040, Madrid, Spain.
Neelsen L; Department of Surgical Pathology, Hospital Clínico San Carlos, Avda. Prof. Martín Lagos s/n, 28040, Madrid, Spain.
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Źródło :
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico [Clin Transl Oncol] 2019 Jul; Vol. 21 (7), pp. 954-959. Date of Electronic Publication: 2018 Dec 18.
Typ publikacji :
Journal Article
MeSH Terms :
Molecular Medicine*
Adenocarcinoma/*pathology
Carcinoma, Pancreatic Ductal/*pathology
Neoplasm Recurrence, Local/*pathology
Pancreatic Neoplasms/*pathology
Pancreaticoduodenectomy/*methods
Adenocarcinoma/surgery ; Aged ; Carcinoma, Pancreatic Ductal/surgery ; Disease Progression ; Female ; Follow-Up Studies ; Humans ; Longitudinal Studies ; Male ; Neoplasm Recurrence, Local/surgery ; Pancreatic Neoplasms/surgery ; Prognosis ; Retrospective Studies
Czasopismo naukowe
Tytuł :
Leveraging the power of new molecular technologies in the clinical setting requires unprecedented awareness of limitations and drawbacks: experience of one diagnostic laboratory.
Autorzy :
Nfonsam L; Department of Genetics, Children's Hospital of Eastern Ontario, Ottawa, Ontario, Canada.
Ordorica S; Department of Genetics, Children's Hospital of Eastern Ontario, Ottawa, Ontario, Canada.
Ghani M; Department of Genetics, Children's Hospital of Eastern Ontario, Ottawa, Ontario, Canada.
Potter R; Department of Genetics, Children's Hospital of Eastern Ontario, Ottawa, Ontario, Canada.
Schaffer A; Department of Genetics, Children's Hospital of Eastern Ontario, Ottawa, Ontario, Canada.
Daoud H; Department of Genetics, Children's Hospital of Eastern Ontario, Ottawa, Ontario, Canada.
Vasli N; Department of Genetics, Children's Hospital of Eastern Ontario, Ottawa, Ontario, Canada.
Chisholm C; Department of Genetics, Children's Hospital of Eastern Ontario, Ottawa, Ontario, Canada.
Sinclair-Bourque E; Department of Genetics, Children's Hospital of Eastern Ontario, Ottawa, Ontario, Canada.
McGowan-Jordan J; Department of Genetics, Children's Hospital of Eastern Ontario, Ottawa, Ontario, Canada.; Department of Pathology and Laboratory Medicine, University of Ottawa, Ottawa, Ontario, Canada.
Smith AC; Department of Genetics, Children's Hospital of Eastern Ontario, Ottawa, Ontario, Canada.; Department of Pathology and Laboratory Medicine, University of Ottawa, Ottawa, Ontario, Canada.
Jarinova O; Department of Genetics, Children's Hospital of Eastern Ontario, Ottawa, Ontario, Canada.; Department of Pathology and Laboratory Medicine, University of Ottawa, Ottawa, Ontario, Canada.
Bronicki L; Department of Genetics, Children's Hospital of Eastern Ontario, Ottawa, Ontario, Canada.; Department of Pathology and Laboratory Medicine, University of Ottawa, Ottawa, Ontario, Canada.
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Źródło :
Journal of medical genetics [J Med Genet] 2019 Jun; Vol. 56 (6), pp. 408-412. Date of Electronic Publication: 2018 Sep 21.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Molecular Diagnostic Techniques*/methods
Molecular Diagnostic Techniques*/standards
Molecular Medicine*/methods
Molecular Medicine*/standards
Alleles ; Computational Biology/methods ; Disease Management ; Gene Duplication ; High-Throughput Nucleotide Sequencing/methods ; Humans ; Molecular Sequence Annotation
Czasopismo naukowe
Tytuł :
Navigating the disease landscape: knowledge representations for contextualizing molecular signatures.
Autorzy :
Saqi M; Mansoor Saqi Data Science Institute, Imperial College London, UK.
Lysenko A; Artem Lysenko Laboratory for Medical Science Mathematics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.
Guo YK; Yi-Ke Guo Data Science Institute, Imperial College London, UK.
Tsunoda T; Tatsuhiko Tsunoda Laboratory for Medical Science Mathematics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan CREST, JST, Tokyo, Japan Department of Medical Science Mathematics, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan.
Auffray C; Charles Auffray European Institute for Systems Biology and Medicine, Lyon, France.
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Źródło :
Briefings in bioinformatics [Brief Bioinform] 2019 Mar 25; Vol. 20 (2), pp. 609-623.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Computational Biology*
Molecular Medicine*
Humans ; Precision Medicine
Czasopismo naukowe
Tytuł :
New North American Editor and 135th Anniversary of Pathology - Research and Practice.
Autorzy :
Roessner A
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Źródło :
Pathology, research and practice [Pathol Res Pract] 2021 Mar; Vol. 219, pp. 153404. Date of Electronic Publication: 2021 Feb 27.
Typ publikacji :
Editorial
MeSH Terms :
Pathology*
Anniversaries and Special Events ; Editorial Policies ; Humans ; Molecular Medicine ; North America ; Periodicals as Topic
Opinia redakcyjna
Tytuł :
CRISPR in Sub-Saharan Africa: Applications and Education.
Autorzy :
Ogaugwu CE; Department of Microbiology and Molecular Genetics, University of California, Irvine, CA 92697-4500, USA; Department of Animal and Environmental Biology, Federal University Oye-Ekiti, 371010 Ekiti State, Nigeria; Laboratory website: http://sites.uci.edu/jameslab. Electronic address: .
Agbo SO; Department of Animal and Environmental Biology, Federal University Oye-Ekiti, 371010 Ekiti State, Nigeria.
Adekoya MA; Department of Plant Science and Biotechnology, Federal University Oye-Ekiti, 371010 Ekiti State, Nigeria.
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Źródło :
Trends in biotechnology [Trends Biotechnol] 2019 Mar; Vol. 37 (3), pp. 234-237. Date of Electronic Publication: 2018 Aug 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
CRISPR-Cas Systems*
Agriculture/*methods
Biotechnology/*methods
Gene Editing/*methods
Molecular Medicine/*methods
Africa South of the Sahara ; Agriculture/education ; Biotechnology/education ; Molecular Medicine/education
Czasopismo naukowe
Tytuł :
Single-Molecule Sequencing: Towards Clinical Applications.
Autorzy :
Ameur A; Department of Immunology, Genetics and Pathology, Uppsala University, Science for Life Laboratory, Uppsala, 75108, Sweden; School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia; All authors contributed equally to this work; ORCID: 0000-0001-6085-6749 (A. Ameur) and 0000-0003-3357-4580 (W.P. Kloosterman). Electronic address: .
Kloosterman WP; Department of Genetics, Center for Molecular Medicine, UMC Utrecht, Utrecht, 3584 CG, The Netherlands; All authors contributed equally to this work; ORCID: 0000-0001-6085-6749 (A. Ameur) and 0000-0003-3357-4580 (W.P. Kloosterman). Electronic address: .
Hestand MS; Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; All authors contributed equally to this work. Electronic address: .
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Źródło :
Trends in biotechnology [Trends Biotechnol] 2019 Jan; Vol. 37 (1), pp. 72-85. Date of Electronic Publication: 2018 Aug 13.
Typ publikacji :
Journal Article; Review
MeSH Terms :
High-Throughput Nucleotide Sequencing/*methods
Molecular Diagnostic Techniques/*methods
Molecular Medicine/*methods
Sequence Analysis, DNA/*methods
Humans ; Molecular Diagnostic Techniques/trends ; Molecular Medicine/trends
Czasopismo naukowe
Tytuł :
Sarcoma treatment in the era of molecular medicine.
Autorzy :
Grünewald TG; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.; Division of Translational Pediatric Sarcoma Research, German Cancer Research Center (DKFZ), Hopp Children's Cancer Center (KiTZ), German Cancer Consortium (DKTK), Heidelberg, Germany.; Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany.
Alonso M; Program in Solid Tumors and Biomarkers, Foundation for the Applied Medical Research, University of Navarra Pamplona, Pamplona, Spain.
Avnet S; Orthopedic Pathophysiology and Regenerative Medicine Unit, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
Banito A; Pediatric Soft Tissue Sarcoma Research Group, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Burdach S; Department of Pediatrics and Children's Cancer Research Center (CCRC), Technische Universität München, Munich, Germany.
Cidre-Aranaz F; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Di Pompo G; Orthopedic Pathophysiology and Regenerative Medicine Unit, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
Distel M; Children's Cancer Research Institute, Vienna, Austria.
Dorado-Garcia H; Department of Pediatric Oncology/Hematology, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Garcia-Castro J; Cellular Biotechnology Unit, Instituto de Salud Carlos III, Madrid, Spain.
González-González L; Cellular Biotechnology Unit, Instituto de Salud Carlos III, Madrid, Spain.
Grigoriadis AE; Centre for Craniofacial and Regenerative Biology, King's College London, London, UK.
Kasan M; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Koelsche C; Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany.
Krumbholz M; Department of Pediatrics, University Hospital, Erlangen, Germany.
Lecanda F; Division of Oncology, Adhesion and Metastasis Laboratory, Center for Applied Medical Research, University of Navarra, Pamplona, Spain.
Lemma S; Orthopedic Pathophysiology and Regenerative Medicine Unit, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
Longo DL; Institute of Biostructures and Bioimaging (IBB), Italian National Research Council (CNR), Turin, Italy.
Madrigal-Esquivel C; Department of Oncology and Metabolism, University of Sheffield, Sheffield, UK.
Morales-Molina Á; Cellular Biotechnology Unit, Instituto de Salud Carlos III, Madrid, Spain.
Musa J; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.; Department of General, Visceral and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany.
Ohmura S; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Ory B; Université de Nantes, Inserm, U1238, Nantes, France.
Pereira-Silva M; Department of Pharmaceutical Technology, Faculty of Pharmacy, University of Coimbra, Coimbra, Portugal.
Perut F; Orthopedic Pathophysiology and Regenerative Medicine Unit, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
Rodriguez R; Instituto de Investigación Sanitaria del Principado de Asturias, Oviedo, Spain.; CIBER en oncología (CIBERONC), Madrid, Spain.
Seeling C; Institute of Pathology, Ulm University, Ulm, Germany.
Al Shaaili N; Department of Oncology and Metabolism, University of Sheffield, Sheffield, UK.
Shaabani S; Department of Drug Design, University of Groningen, Groningen, The Netherlands.
Shiavone K; Department of Oncology and Metabolism, University of Sheffield, Sheffield, UK.
Sinha S; Department of Oral and Maxillofacial Diseases, University of Helsinki, Helsinki, Finland.
Tomazou EM; Children's Cancer Research Institute, Vienna, Austria.
Trautmann M; Division of Translational Pathology, Gerhard-Domagk-Institute of Pathology, Münster University Hospital, Münster, Germany.
Vela M; Hospital La Paz Institute for Health Research (IdiPAZ), Madrid, Spain.
Versleijen-Jonkers YM; Department of Medical Oncology, Radboud University Medical Center, Nijmegen, The Netherlands.
Visgauss J; Medical Center, Duke University, Durham, NC, USA.
Zalacain M; Institute of Biostructures and Bioimaging (IBB), Italian National Research Council (CNR), Turin, Italy.
Schober SJ; Department of Pediatrics and Children's Cancer Research Center (CCRC), Technische Universität München, Munich, Germany.
Lissat A; University Children's Hospital Zurich - Eleonoren Foundation, Kanton Zürich, Zürich, Switzerland.
English WR; Department of Oncology and Metabolism, University of Sheffield, Sheffield, UK.
Baldini N; Orthopedic Pathophysiology and Regenerative Medicine Unit, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.; Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy.
Heymann D; Department of Oncology and Metabolism, University of Sheffield, Sheffield, UK.; Université de Nantes, Institut de Cancérologie de l'Ouest, Tumor Heterogeneity and Precision Medicine, Saint-Herblain, France.
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Źródło :
EMBO molecular medicine [EMBO Mol Med] 2020 Nov 06; Vol. 12 (11), pp. e11131. Date of Electronic Publication: 2020 Oct 13.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Bone Neoplasms*
Osteosarcoma*
Sarcoma*/genetics
Sarcoma*/therapy
Soft Tissue Neoplasms*
Adolescent ; Child ; Humans ; Molecular Medicine
Czasopismo naukowe
Tytuł :
High-resolution ex vivo NMR spectroscopy of human Z α 1 -antitrypsin.
Autorzy :
Jagger AM; UCL Respiratory, Rayne Institute, University College London, London, WC1E 6JF, UK.; Institute of Structural and Molecular Biology, University College London and School of Crystallography, Birkbeck College, University of London, Gower Street, London, WC1E 6BT, UK.
Waudby CA; Institute of Structural and Molecular Biology, University College London and School of Crystallography, Birkbeck College, University of London, Gower Street, London, WC1E 6BT, UK.
Irving JA; UCL Respiratory, Rayne Institute, University College London, London, WC1E 6JF, UK. .; Institute of Structural and Molecular Biology, University College London and School of Crystallography, Birkbeck College, University of London, Gower Street, London, WC1E 6BT, UK. .
Christodoulou J; Institute of Structural and Molecular Biology, University College London and School of Crystallography, Birkbeck College, University of London, Gower Street, London, WC1E 6BT, UK. .
Lomas DA; UCL Respiratory, Rayne Institute, University College London, London, WC1E 6JF, UK. .; Institute of Structural and Molecular Biology, University College London and School of Crystallography, Birkbeck College, University of London, Gower Street, London, WC1E 6BT, UK. .
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Źródło :
Nature communications [Nat Commun] 2020 Dec 11; Vol. 11 (1), pp. 6371. Date of Electronic Publication: 2020 Dec 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Magnetic Resonance Spectroscopy/*methods
alpha 1-Antitrypsin/*chemistry
alpha 1-Antitrypsin/*genetics
alpha 1-Antitrypsin/*metabolism
alpha 1-Antitrypsin Deficiency/*genetics
alpha 1-Antitrypsin Deficiency/*metabolism
Genetic Predisposition to Disease/genetics ; Glycoproteins ; Humans ; Models, Molecular ; Molecular Medicine ; Mutation ; Protein Aggregation, Pathological ; Protein Conformation ; Recombinant Proteins ; Serine Proteinase Inhibitors/chemistry
Czasopismo naukowe
Tytuł :
Inhibition of aquaporin-3 in macrophages by a monoclonal antibody as potential therapy for liver injury.
Autorzy :
Hara-Chikuma M; Department of Pharmacology, School of Medicine, Keio University, Tokyo, Japan. .
Tanaka M; Department of Pharmacology, School of Medicine, Keio University, Tokyo, Japan.; Keio Global Research Institute, Center for Water Biology and Medicine, Tokyo, Japan.
Verkman AS; Departments of Medicine and Physiology, University of California San Francisco, San Francisco, CA, USA.
Yasui M; Department of Pharmacology, School of Medicine, Keio University, Tokyo, Japan.; Keio Global Research Institute, Center for Water Biology and Medicine, Tokyo, Japan.
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Źródło :
Nature communications [Nat Commun] 2020 Nov 09; Vol. 11 (1), pp. 5666. Date of Electronic Publication: 2020 Nov 09.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Antibodies, Monoclonal/*pharmacology
Aquaporin 3/*antagonists & inhibitors
Aquaporin 3/*metabolism
Chemical and Drug Induced Liver Injury/*drug therapy
Macrophages/*drug effects
Macrophages/*metabolism
Animals ; Aquaporin 3/genetics ; CHO Cells ; Chemical and Drug Induced Liver Injury/pathology ; Chemical and Drug Induced Liver Injury/prevention & control ; Chemokine CCL4/adverse effects ; Cricetulus ; Disease Models, Animal ; Drug Discovery ; Glycerol/metabolism ; Hydrogen Peroxide/metabolism ; Liver/metabolism ; Liver/pathology ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Molecular Medicine ; NF-kappa B/metabolism ; Oxidative Stress ; Signal Transduction ; Transcriptome
Czasopismo naukowe

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