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Wyszukujesz frazę ""Molecular Sequence Data"" wg kryterium: Temat


Tytuł :
Molecular underpinnings of ssDNA specificity by Rep HUH-endonucleases and implications for HUH-tag multiplexing and engineering.
Autorzy :
Tompkins KJ; Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota Twin Cities, Minneapolis, MN 55455, USA.
Houtti M; Department of Computer Science and Engineering, University of Minnesota Twin Cities, Minneapolis, MN 55455, USA.
Litzau LA; Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota Twin Cities, Minneapolis, MN 55455, USA.
Aird EJ; Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota Twin Cities, Minneapolis, MN 55455, USA.
Everett BA; Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota Twin Cities, Minneapolis, MN 55455, USA.
Nelson AT; Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota Twin Cities, Minneapolis, MN 55455, USA.
Pornschloegl L; Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota Twin Cities, Minneapolis, MN 55455, USA.
Limón-Swanson LK; Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota Twin Cities, Minneapolis, MN 55455, USA.
Evans RL; Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota Twin Cities, Minneapolis, MN 55455, USA.
Evans K; Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota Twin Cities, Minneapolis, MN 55455, USA.
Shi K; Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota Twin Cities, Minneapolis, MN 55455, USA.
Aihara H; Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota Twin Cities, Minneapolis, MN 55455, USA.
Gordon WR; Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota Twin Cities, Minneapolis, MN 55455, USA.
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Źródło :
Nucleic acids research [Nucleic Acids Res] 2021 Jan 25; Vol. 49 (2), pp. 1046-1064.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Nucleic Acid Conformation*
Protein Conformation*
DNA Helicases/*metabolism
DNA, Single-Stranded/*metabolism
Deoxyribonuclease I/*metabolism
Protein Engineering/*methods
Single-Strand Specific DNA and RNA Endonucleases/*metabolism
Trans-Activators/*metabolism
Viral Proteins/*metabolism
Amino Acid Motifs ; Amino Acid Sequence ; Circoviridae/enzymology ; Conserved Sequence ; Crystallography, X-Ray ; DNA Helicases/chemistry ; DNA, Single-Stranded/chemistry ; Deoxyribonuclease I/chemistry ; Gene Library ; Models, Molecular ; Molecular Docking Simulation ; Molecular Sequence Data ; Plant Viruses/enzymology ; Protein Binding ; Recombinant Fusion Proteins/chemistry ; Recombinant Fusion Proteins/metabolism ; Replication Origin ; Sequence Alignment ; Sequence Homology, Amino Acid ; Single-Strand Specific DNA and RNA Endonucleases/chemistry ; Substrate Specificity ; Trans-Activators/chemistry ; Viral Proteins/chemistry
Czasopismo naukowe
Tytuł :
Analysis of mutations of defensin protein using accelerated molecular dynamics simulations.
Autorzy :
Pandey B; School of Biotechnology, Jawaharlal Nehru University, New Delhi, India.
Tyagi C; Department of Microbiology, Faculty of Science and Informatics, University of Szeged, Szeged, Hungary.
Prajapati GK; Department of Bio-Engineering, Birla Institute of Technology, Mesra, Ranchi, Jharkhand, India.
Mishra AK; Department of Biotechnology, Yeungnam University, Gyeongsan, Gyeongbuk, Republic of Korea.
Hashem A; Botany and Microbiology Department, College of Science, King Saud University, Riyadh, Saudi Arabia.; Mycology and Plant Disease Survey Department, Plant Pathology Research Institute, ARC, Giza, Egypt.
Alqarawi AA; Plant Production Department, College of Food and Agricultural Sciences, King Saud University, Riyadh, Saudi Arabia.
Abd Allah EF; Plant Production Department, College of Food and Agricultural Sciences, King Saud University, Riyadh, Saudi Arabia.
Mohanta TK; Natural and Medical Sciences Research Center, University of Nizwa, Nizwa, Oman.
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Źródło :
PloS one [PLoS One] 2020 Nov 30; Vol. 15 (11), pp. e0241679. Date of Electronic Publication: 2020 Nov 30 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Molecular Dynamics Simulation*
Defensins/*chemistry
Defensins/*genetics
Amino Acid Sequence ; Deuterium/chemistry ; Molecular Sequence Data ; Mutation/genetics ; Sequence Alignment ; Sequence Homology, Amino Acid
Czasopismo naukowe
Tytuł :
A revision of the planthopper genus Chionomus Fennah (Hemiptera: Fulgoroidea: Delphacidae).
Autorzy :
Weglarz KM; Department of Biology, 3505 Old Main Hill, Utah State University, Logan, UT 84322. .
Bartlett CR
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Źródło :
Zootaxa [Zootaxa] 2020 Jul 14; Vol. 4811 (1), pp. zootaxa.4811.1.1. Date of Electronic Publication: 2020 Jul 14.
Typ publikacji :
Journal Article
MeSH Terms :
Hemiptera*
Animals ; Bayes Theorem ; Genes, Mitochondrial ; Molecular Sequence Data ; Phylogeny
Czasopismo naukowe
Tytuł :
ShAn: An easy-to-use tool for interactive and integrated variant annotation.
Autorzy :
Rathinakannan VS; Institute of Biomedicine, University of Turku, Turku, Finland.
Schukov HP; Institute of Biomedicine, University of Turku, Turku, Finland.
Heron S; Institute of Biomedicine, University of Turku, Turku, Finland.
Schleutker J; Institute of Biomedicine, University of Turku, Turku, Finland.; Department of Medical Genetics,Genomics, Division of Laboratory, Turku University Hospital, Turku, Finland.
Sipeky C; Institute of Biomedicine, University of Turku, Turku, Finland.
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Źródło :
PloS one [PLoS One] 2020 Jul 07; Vol. 15 (7), pp. e0235669. Date of Electronic Publication: 2020 Jul 07 (Print Publication: 2020).
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Validation Study
MeSH Terms :
Software*
Molecular Sequence Annotation/*methods
Databases, Genetic ; Datasets as Topic ; Humans ; Molecular Sequence Data
Czasopismo naukowe
Tytuł :
Genetic risk prediction using a spatial autoregressive model with adaptive lasso.
Autorzy :
Wen Y; Department of Statistics, University of Auckland, Auckland, New Zealand.
Shen X; Department of Epidemiology and Biostatistics, Michigan State University, East Lansing, Michigan, USA.
Lu Q; Department of Epidemiology and Biostatistics, Michigan State University, East Lansing, Michigan, USA.
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Źródło :
Statistics in medicine [Stat Med] 2018 Nov 20; Vol. 37 (26), pp. 3764-3775. Date of Electronic Publication: 2018 May 31.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Genetic Predisposition to Disease*
Molecular Sequence Data*
Algorithms ; Humans ; Models, Genetic ; Models, Statistical ; Precision Medicine ; Regression Analysis
Czasopismo naukowe
Tytuł :
Identification, Cloning and Heterologous Expression of the Gene Cluster Directing RES-701-3, -4 Lasso Peptides Biosynthesis from a Marine Streptomyces Strain.
Autorzy :
Oves-Costales D; Fundación MEDINA, Centro de Excelencia en Investigación de Medicamentos Innovadores en Andalucía, Avda del Conocimiento 34, 18016 Armilla (Granada), Spain.
Sánchez-Hidalgo M; Fundación MEDINA, Centro de Excelencia en Investigación de Medicamentos Innovadores en Andalucía, Avda del Conocimiento 34, 18016 Armilla (Granada), Spain.
Martín J; Fundación MEDINA, Centro de Excelencia en Investigación de Medicamentos Innovadores en Andalucía, Avda del Conocimiento 34, 18016 Armilla (Granada), Spain.
Genilloud O; Fundación MEDINA, Centro de Excelencia en Investigación de Medicamentos Innovadores en Andalucía, Avda del Conocimiento 34, 18016 Armilla (Granada), Spain.
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Źródło :
Marine drugs [Mar Drugs] 2020 May 01; Vol. 18 (5). Date of Electronic Publication: 2020 May 01.
Typ publikacji :
Journal Article
MeSH Terms :
Peptides, Cyclic/*biosynthesis
Streptomyces/*metabolism
Amino Acid Sequence ; Animals ; Cloning, Molecular ; Gene Expression Regulation ; Molecular Sequence Data ; Peptides, Cyclic/genetics
SCR Organism :
Streptomyces caniferus
Czasopismo naukowe
Tytuł :
Perturbing proteomes at single residue resolution using base editing.
Autorzy :
Després PC; Département de Biochimie, Microbiologie et Bio-informatique, Faculté de Sciences et Génie, Université Laval, Québec, QC, G1V 0A6, Canada.; PROTEO, le regroupement québécois de recherche sur la fonction, l'ingénierie et les applications des protéines, Université Laval, Québec, QC, G1V 0A6, Canada.; Centre de Recherche en Données Massives (CRDM), Université Laval, Québec, QC, G1V 0A6, Canada.; Institut de Biologie Intégrative et des Systèmes, Université Laval, Québec, QC, G1V 0A6, Canada.
Dubé AK; Département de Biochimie, Microbiologie et Bio-informatique, Faculté de Sciences et Génie, Université Laval, Québec, QC, G1V 0A6, Canada.; PROTEO, le regroupement québécois de recherche sur la fonction, l'ingénierie et les applications des protéines, Université Laval, Québec, QC, G1V 0A6, Canada.; Centre de Recherche en Données Massives (CRDM), Université Laval, Québec, QC, G1V 0A6, Canada.; Institut de Biologie Intégrative et des Systèmes, Université Laval, Québec, QC, G1V 0A6, Canada.; Département de Biologie, Faculté de Sciences et Génie, Université Laval, Québec, QC, G1V 0A6, Canada.
Seki M; Research Center for Advanced Science and Technology, Synthetic Biology Division, University of Tokyo, Tokyo, 4-6-1 Komaba, Meguro-ku, 153-8904, Japan.
Yachie N; Research Center for Advanced Science and Technology, Synthetic Biology Division, University of Tokyo, Tokyo, 4-6-1 Komaba, Meguro-ku, 153-8904, Japan. .; Department of Biological Sciences, Graduate School of Science, the University of Tokyo, Tokyo, Japan. .; Institute for Advanced Biosciences, Keio University, Tsuruoka, Japan. .
Landry CR; Département de Biochimie, Microbiologie et Bio-informatique, Faculté de Sciences et Génie, Université Laval, Québec, QC, G1V 0A6, Canada. .; PROTEO, le regroupement québécois de recherche sur la fonction, l'ingénierie et les applications des protéines, Université Laval, Québec, QC, G1V 0A6, Canada. .; Centre de Recherche en Données Massives (CRDM), Université Laval, Québec, QC, G1V 0A6, Canada. .; Institut de Biologie Intégrative et des Systèmes, Université Laval, Québec, QC, G1V 0A6, Canada. .; Département de Biologie, Faculté de Sciences et Génie, Université Laval, Québec, QC, G1V 0A6, Canada. .
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Źródło :
Nature communications [Nat Commun] 2020 Apr 20; Vol. 11 (1), pp. 1871. Date of Electronic Publication: 2020 Apr 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Clustered Regularly Interspaced Short Palindromic Repeats*
High-Throughput Screening Assays*
Gene Editing/*methods
Proteome/*genetics
Yeasts/*genetics
Base Sequence ; CRISPR-Cas Systems ; Genes, Essential ; Genome ; Genome, Fungal ; High-Throughput Nucleotide Sequencing ; Molecular Sequence Data ; Mutagenesis ; Mutation ; RNA, Guide/genetics
Czasopismo naukowe
Tytuł :
Biochemical features of the novel Tail Tubular Protein A of Yersinia phage phiYeO3-12.
Autorzy :
Pyra A; University of Wroclaw, Faculty of Chemistry, 14F. Joliot-Curie St, Wroclaw, 50383, Poland. .
Urbańska N; University of Wroclaw, Faculty of Biological Sciences, Institute of Experimental Biology, 6 Kanonia St, Wroclaw, 50328, Poland.; Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, 12R. Weigl St, Wroclaw, 53114, Poland.
Filik K; Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, 12R. Weigl St, Wroclaw, 53114, Poland.
Tyrlik K; Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, 12R. Weigl St, Wroclaw, 53114, Poland.
Brzozowska E; Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, 12R. Weigl St, Wroclaw, 53114, Poland. .
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Źródło :
Scientific reports [Sci Rep] 2020 Mar 06; Vol. 10 (1), pp. 4196. Date of Electronic Publication: 2020 Mar 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Viral Proteins/*chemistry
Viral Proteins/*metabolism
Amino Acid Sequence ; Bacteriophages/genetics ; Genome, Viral/genetics ; Hydrolysis ; Molecular Sequence Data ; Viral Proteins/genetics
Czasopismo naukowe
Tytuł :
A single Asp isomer substitution in an αA-crystallin-derived peptide induces a large change in peptide properties.
Autorzy :
Magami K; Department of Chemistry, Graduate School of Science, Kyoto University, Sakyo-ku, Kyoto, 606-8502, Japan.
Kim I; Institute for Integrated Radiation and Nuclear Science, Kyoto University, Kumatori, Sennan, Osaka, 590-0494, Japan.
Fujii N; Institute for Integrated Radiation and Nuclear Science, Kyoto University, Kumatori, Sennan, Osaka, 590-0494, Japan. Electronic address: .
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Źródło :
Experimental eye research [Exp Eye Res] 2020 Mar; Vol. 192, pp. 107930. Date of Electronic Publication: 2020 Jan 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Aspartic Acid/*chemistry
Lens, Crystalline/*chemistry
Peptide Fragments/*chemistry
alpha-Crystallin A Chain/*chemistry
Amino Acid Sequence ; Amino Acid Substitution ; Animals ; Cattle ; Chromatography, Liquid ; Circular Dichroism ; Isomerism ; Molecular Chaperones/chemistry ; Molecular Sequence Data ; Protein Aggregation, Pathological ; Protein Conformation ; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
Czasopismo naukowe
Tytuł :
Microbial Synthesis of Antibacterial Phenazine-1,6-dicarboxylic Acid and the Role of PhzG in Pseudomonas chlororaphis GP72AN.
Autorzy :
Guo S; State Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology , Shanghai Jiao Tong University , Shanghai 200240 , China.
Wang Y; State Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology , Shanghai Jiao Tong University , Shanghai 200240 , China.
Bilal M; State Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology , Shanghai Jiao Tong University , Shanghai 200240 , China.
Hu H; State Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology , Shanghai Jiao Tong University , Shanghai 200240 , China.; National Experimental Teaching Center for Life Sciences and Biotechnology , Shanghai Jiao Tong University , Shanghai 200240 , China.
Wang W; State Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology , Shanghai Jiao Tong University , Shanghai 200240 , China.
Zhang X; State Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology , Shanghai Jiao Tong University , Shanghai 200240 , China.
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Źródło :
Journal of agricultural and food chemistry [J Agric Food Chem] 2020 Feb 26; Vol. 68 (8), pp. 2373-2380. Date of Electronic Publication: 2020 Feb 17.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Bacterial Agents/*biosynthesis
Bacterial Proteins/*metabolism
Phenazines/*metabolism
Pseudomonas chlororaphis/*genetics
Pseudomonas chlororaphis/*metabolism
Amino Acid Sequence ; Bacterial Proteins/chemistry ; Bacterial Proteins/genetics ; Gene Deletion ; Molecular Sequence Data ; Pseudomonas chlororaphis/enzymology ; Sequence Alignment
Czasopismo naukowe
Tytuł :
A review of mathematical representations of biomolecular data.
Autorzy :
Nguyen DD; Department of Mathematics, Michigan State University, MI 48824, USA. .
Cang Z; Department of Mathematics, Michigan State University, MI 48824, USA. .
Wei GW; Department of Mathematics, Michigan State University, MI 48824, USA. and Department of Biochemistry and Molecular Biology, Michigan State University, MI 48824, USA and Department of Electrical and Computer Engineering, Michigan State University, MI 48824, USA.
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Źródło :
Physical chemistry chemical physics : PCCP [Phys Chem Chem Phys] 2020 Feb 26; Vol. 22 (8), pp. 4343-4367.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Computational Biology*
Models, Biological*
Algorithms ; Molecular Sequence Data
Czasopismo naukowe
Tytuł :
Identification of a Spermidine Synthase Gene from Soybean by Recombinant Expression, Transcriptional Verification, and Sequence Analysis.
Autorzy :
Zou D; Beijing Advanced Innovation Center for Food Nutrition and Human Health , Beijing Technology and Business University (BTBU) , Beijing 100048 , China.; Key Laboratory of Environment Correlative Dietology (Ministry of Education), College of Food Science and Technology , Huazhong Agricultural University , Wuhan 430070 , China.
Min Y; Beijing Advanced Innovation Center for Food Nutrition and Human Health , Beijing Technology and Business University (BTBU) , Beijing 100048 , China.; Key Laboratory of Environment Correlative Dietology (Ministry of Education), College of Food Science and Technology , Huazhong Agricultural University , Wuhan 430070 , China.
Liu Y; Beijing Advanced Innovation Center for Food Nutrition and Human Health , Beijing Technology and Business University (BTBU) , Beijing 100048 , China.
Wei X; Beijing Advanced Innovation Center for Food Nutrition and Human Health , Beijing Technology and Business University (BTBU) , Beijing 100048 , China.; Key Laboratory of Environment Correlative Dietology (Ministry of Education), College of Food Science and Technology , Huazhong Agricultural University , Wuhan 430070 , China.
Wang J; Beijing Advanced Innovation Center for Food Nutrition and Human Health , Beijing Technology and Business University (BTBU) , Beijing 100048 , China.
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Źródło :
Journal of agricultural and food chemistry [J Agric Food Chem] 2020 Feb 26; Vol. 68 (8), pp. 2366-2372. Date of Electronic Publication: 2020 Feb 13.
Typ publikacji :
Journal Article
MeSH Terms :
Plant Proteins/*genetics
Soybeans/*enzymology
Spermidine Synthase/*genetics
Amino Acid Sequence ; Bacillus amyloliquefaciens/genetics ; Bacillus amyloliquefaciens/metabolism ; Germination ; Molecular Sequence Data ; Plant Proteins/chemistry ; Plant Proteins/metabolism ; Recombinant Proteins/chemistry ; Recombinant Proteins/genetics ; Recombinant Proteins/metabolism ; Seeds/enzymology ; Seeds/genetics ; Seeds/growth & development ; Seeds/metabolism ; Sequence Alignment ; Soybeans/genetics ; Soybeans/growth & development ; Soybeans/metabolism ; Spermidine/metabolism ; Spermidine Synthase/chemistry ; Spermidine Synthase/metabolism ; Transcription, Genetic
Czasopismo naukowe
Tytuł :
Structural Insights Into PfARO and Characterization of its Interaction With PfAIP.
Autorzy :
Geiger M; Centre for Structural Systems Biology, Notkestraße 85, 22607, Hamburg, Germany; Bernhard Nocht Institute for Tropical Medicine, Bernhard-Nocht-Strasse 74, 20359, Hamburg, Germany; Department of Biology, University of Hamburg, Hamburg, Germany.
Brown C; Western University, Department of Biochemistry, London, ON, Canada.
Wichers JS; Centre for Structural Systems Biology, Notkestraße 85, 22607, Hamburg, Germany; Bernhard Nocht Institute for Tropical Medicine, Bernhard-Nocht-Strasse 74, 20359, Hamburg, Germany; Department of Biology, University of Hamburg, Hamburg, Germany.
Strauss J; Centre for Structural Systems Biology, Notkestraße 85, 22607, Hamburg, Germany; Bernhard Nocht Institute for Tropical Medicine, Bernhard-Nocht-Strasse 74, 20359, Hamburg, Germany; Department of Biology, University of Hamburg, Hamburg, Germany.
Lill A; Centre for Structural Systems Biology, Notkestraße 85, 22607, Hamburg, Germany; Department of Biology, University of Hamburg, Hamburg, Germany.
Thuenauer R; Centre for Structural Systems Biology, Notkestraße 85, 22607, Hamburg, Germany; Department of Biology, University of Hamburg, Hamburg, Germany.
Liffner B; Research Centre for Infectious Diseases, School of Biological Sciences, University of Adelaide, Adelaide, Australia.
Wilcke L; Centre for Structural Systems Biology, Notkestraße 85, 22607, Hamburg, Germany; Bernhard Nocht Institute for Tropical Medicine, Bernhard-Nocht-Strasse 74, 20359, Hamburg, Germany.
Lemcke S; Centre for Structural Systems Biology, Notkestraße 85, 22607, Hamburg, Germany; Bernhard Nocht Institute for Tropical Medicine, Bernhard-Nocht-Strasse 74, 20359, Hamburg, Germany; Department of Biology, University of Hamburg, Hamburg, Germany.
Heincke D; Centre for Structural Systems Biology, Notkestraße 85, 22607, Hamburg, Germany; Bernhard Nocht Institute for Tropical Medicine, Bernhard-Nocht-Strasse 74, 20359, Hamburg, Germany; Department of Biology, University of Hamburg, Hamburg, Germany.
Pazicky S; Centre for Structural Systems Biology, Notkestraße 85, 22607, Hamburg, Germany; Molecular Biology Laboratory (EMBL), Hamburg Unit c/o Deutsches Elektronen Synchrotron (DESY), Notkestrasse 85, 22607, Hamburg, Germany.
Bachmann A; Centre for Structural Systems Biology, Notkestraße 85, 22607, Hamburg, Germany; Bernhard Nocht Institute for Tropical Medicine, Bernhard-Nocht-Strasse 74, 20359, Hamburg, Germany; Department of Biology, University of Hamburg, Hamburg, Germany.
Löw C; Centre for Structural Systems Biology, Notkestraße 85, 22607, Hamburg, Germany; Molecular Biology Laboratory (EMBL), Hamburg Unit c/o Deutsches Elektronen Synchrotron (DESY), Notkestrasse 85, 22607, Hamburg, Germany.
Wilson DW; Research Centre for Infectious Diseases, School of Biological Sciences, University of Adelaide, Adelaide, Australia; Burnet Institute, 85 Commercial Road, Melbourne, 3004, Victoria, Australia.
Filarsky M; Centre for Structural Systems Biology, Notkestraße 85, 22607, Hamburg, Germany; Department of Biology, University of Hamburg, Hamburg, Germany.
Burda PC; Centre for Structural Systems Biology, Notkestraße 85, 22607, Hamburg, Germany; Bernhard Nocht Institute for Tropical Medicine, Bernhard-Nocht-Strasse 74, 20359, Hamburg, Germany; Department of Biology, University of Hamburg, Hamburg, Germany.
Zhang K; Western University, Department of Biochemistry, London, ON, Canada.
Junop M; Western University, Department of Biochemistry, London, ON, Canada. Electronic address: .
Gilberger TW; Centre for Structural Systems Biology, Notkestraße 85, 22607, Hamburg, Germany; Bernhard Nocht Institute for Tropical Medicine, Bernhard-Nocht-Strasse 74, 20359, Hamburg, Germany; Department of Biology, University of Hamburg, Hamburg, Germany. Electronic address: .
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Źródło :
Journal of molecular biology [J Mol Biol] 2020 Feb 14; Vol. 432 (4), pp. 878-896. Date of Electronic Publication: 2019 Dec 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Plasmodium falciparum/*metabolism
Plasmodium falciparum/*pathogenicity
Protozoan Proteins/*metabolism
Amino Acid Sequence ; Animals ; Armadillo Domain Proteins/genetics ; Armadillo Domain Proteins/metabolism ; Humans ; Malaria/physiopathology ; Molecular Sequence Data ; Mutagenesis/genetics ; Mutagenesis/physiology ; Mutation ; Parasitemia/parasitology ; Phylogeny ; Plasmodium falciparum/genetics ; Protein Transport/genetics ; Protein Transport/physiology ; Protozoan Proteins/genetics
Czasopismo naukowe
Tytuł :
The First Structure of an Active Mammalian dCTPase and its Complexes With Substrate Analogs and Products.
Autorzy :
Scaletti E; Department of Experimental Medical Science, Lund University, Lund, 221 00, Sweden; Department of Biochemistry and Biophysics, Stockholm University, Stockholm, S-106 91, Sweden.
Claesson M; Department of Biochemistry and Biophysics, Stockholm University, Stockholm, S-106 91, Sweden.
Helleday T; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, Stockholm, S-171 76, Sweden; Sheffield Cancer Centre, Department of Oncology and Metabolism, University of Sheffield, Sheffield, S10 2RX, UK.
Jemth AS; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, Stockholm, S-171 76, Sweden. Electronic address: .
Stenmark P; Department of Experimental Medical Science, Lund University, Lund, 221 00, Sweden; Department of Biochemistry and Biophysics, Stockholm University, Stockholm, S-106 91, Sweden. Electronic address: .
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Źródło :
Journal of molecular biology [J Mol Biol] 2020 Feb 14; Vol. 432 (4), pp. 1126-1142. Date of Electronic Publication: 2020 Jan 15.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Phosphoric Monoester Hydrolases/*metabolism
Pyrophosphatases/*chemistry
Pyrophosphatases/*metabolism
Amino Acid Sequence ; Animals ; DNA Damage/genetics ; Deoxycytosine Nucleotides/metabolism ; Epigenomics ; Humans ; Kinetics ; Mice ; Molecular Sequence Data ; Phosphoric Monoester Hydrolases/chemistry ; Phosphoric Monoester Hydrolases/genetics ; Protein Binding ; Protein Structure, Secondary ; Pyrophosphatases/genetics
Czasopismo naukowe
Tytuł :
An Illumina approach to MHC typing of Atlantic salmon.
Autorzy :
Sundaram AYM; Norwegian Veterinary Institute, P.O. Box 750 Sentrum, 0106, Oslo, Norway.; Department of Medical Genetics, Oslo University Hospital, 0450, Oslo, Norway.
Garseth ÅH; Norwegian Veterinary Institute, P.O. Box 750 Sentrum, 0106, Oslo, Norway.
Maccari G; The Pirbright Institute, Woking, UK.; Anthony Nolan Research Institute, London, UK.
Grimholt U; Norwegian Veterinary Institute, P.O. Box 750 Sentrum, 0106, Oslo, Norway. .
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Źródło :
Immunogenetics [Immunogenetics] 2020 Feb; Vol. 72 (1-2), pp. 89-100. Date of Electronic Publication: 2019 Nov 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Major Histocompatibility Complex/*genetics
Salmo salar/*genetics
Salmo salar/*immunology
Alleles ; Animals ; Databases, Factual ; Evolution, Molecular ; Genetic Variation ; Genome ; High-Throughput Nucleotide Sequencing/methods ; Molecular Sequence Data ; Phylogeny ; Sequence Alignment ; Sequence Analysis, Protein
Czasopismo naukowe
Tytuł :
Fluorescent Reporter Zebrafish Line for Estrogenic Compound Screening Generated Using a CRISPR/Cas9-Mediated Knock-in System.
Autorzy :
Abdelmoneim A; Department of Food Science, College of Agriculture and Life Sciences, Cornell University, Ithaca, New York 14853.; Department of Veterinary Forensic Medicine and Toxicology, Assiut University, Assiut, Egypt.
Clark CL; Department of Food Science, College of Agriculture and Life Sciences, Cornell University, Ithaca, New York 14853.
Mukai M; Department of Food Science, College of Agriculture and Life Sciences, Cornell University, Ithaca, New York 14853.
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Źródło :
Toxicological sciences : an official journal of the Society of Toxicology [Toxicol Sci] 2020 Feb 01; Vol. 173 (2), pp. 336-346.
Typ publikacji :
Journal Article
MeSH Terms :
CRISPR-Cas Systems*
Estrogens/*metabolism
Estrogens/*pharmacology
Gene Knock-In Techniques/*methods
Green Fluorescent Proteins/*metabolism
Animals ; Animals, Genetically Modified ; Benzhydryl Compounds/pharmacology ; Embryo, Nonmammalian/drug effects ; Embryo, Nonmammalian/metabolism ; Endocrine Disruptors/pharmacology ; Environmental Monitoring/methods ; Estradiol/pharmacology ; Gene Expression Regulation/drug effects ; Green Fluorescent Proteins/genetics ; Larva/metabolism ; Liver/metabolism ; Molecular Sequence Data ; Phenols/pharmacology ; RNA, Messenger/metabolism ; Vitellogenins/genetics ; Vitellogenins/metabolism ; Zebrafish/genetics ; Zebrafish/metabolism ; Zebrafish Proteins/genetics ; Zebrafish Proteins/metabolism
Czasopismo naukowe
Tytuł :
Interim estimates of 2019/20 vaccine effectiveness during early-season co-circulation of influenza A and B viruses, Canada, February 2020.
Autorzy :
Skowronski DM; University of British Columbia, Vancouver, Canada.; British Columbia Centre for Disease Control, Vancouver, Canada.
Zou M; British Columbia Centre for Disease Control, Vancouver, Canada.
Sabaiduc S; British Columbia Centre for Disease Control, Vancouver, Canada.
Murti M; University of Toronto, Toronto, Canada.; Public Health Ontario, Toronto, Canada.
Olsha R; Public Health Ontario, Toronto, Canada.
Dickinson JA; University of Calgary, Calgary, Canada.
Gubbay JB; University of Toronto, Toronto, Canada.; Public Health Ontario, Toronto, Canada.
Croxen MA; University of Alberta, Edmonton, Canada.; Public Health Laboratory (ProvLab), Alberta Precision Laboratories, Edmonton, Alberta, Canada.
Charest H; Institut National de Santé Publique du Québec, Québec, Canada.
Jassem A; University of British Columbia, Vancouver, Canada.; British Columbia Centre for Disease Control, Vancouver, Canada.
Krajden M; University of British Columbia, Vancouver, Canada.; British Columbia Centre for Disease Control, Vancouver, Canada.
Bastien N; National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Canada.
Li Y; National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Canada.
De Serres G; Centre Hospitalier Universitaire de Québec, Québec, Canada.; Laval University, Quebec, Canada.; Institut National de Santé Publique du Québec, Québec, Canada.
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Źródło :
Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin [Euro Surveill] 2020 Feb; Vol. 25 (7).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Influenza A Virus, H1N1 Subtype/*isolation & purification
Influenza A Virus, H3N2 Subtype/*isolation & purification
Influenza B virus/*isolation & purification
Influenza Vaccines/*administration & dosage
Influenza, Human/*epidemiology
Influenza, Human/*prevention & control
Adolescent ; Adult ; Aged ; Antigens, Viral/analysis ; Canada/epidemiology ; Child ; Child, Preschool ; Female ; Genotype ; Hemagglutination Inhibition Tests ; Humans ; Infant ; Influenza A Virus, H1N1 Subtype/genetics ; Influenza A Virus, H1N1 Subtype/immunology ; Influenza A Virus, H3N2 Subtype/genetics ; Influenza A Virus, H3N2 Subtype/immunology ; Influenza B virus/genetics ; Influenza B virus/immunology ; Influenza Vaccines/immunology ; Male ; Middle Aged ; Molecular Sequence Data ; Nasopharynx/virology ; Nose/virology ; Real-Time Polymerase Chain Reaction ; Seasons ; Sentinel Surveillance ; Sequence Analysis, DNA ; Young Adult
Czasopismo naukowe
Tytuł :
Revealing factors determining immunodominant responses against dominant epitopes.
Autorzy :
Ritmahan W; The Centre for Integrative Bioinformatics VU, Vrije Universiteit, Amsterdam, The Netherlands. .; Theoretical Biology, Utrecht University, Utrecht, The Netherlands. .
Kesmir C; Theoretical Biology, Utrecht University, Utrecht, The Netherlands.
Vroomans RMA; Theoretical Biology, Utrecht University, Utrecht, The Netherlands.; Institute for Advanced Study, University of Amsterdam, Amsterdam, The Netherlands.
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Źródło :
Immunogenetics [Immunogenetics] 2020 Feb; Vol. 72 (1-2), pp. 109-118. Date of Electronic Publication: 2019 Dec 06.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Complementarity Determining Regions/*genetics
Immunodominant Epitopes/*genetics
Receptors, Antigen, T-Cell/*genetics
Amino Acid Sequence ; CD8-Positive T-Lymphocytes/immunology ; Complementarity Determining Regions/metabolism ; Databases, Factual ; Epitopes/genetics ; Epitopes/immunology ; Epitopes, T-Lymphocyte/immunology ; Humans ; Immunity, Cellular ; Immunodominant Epitopes/immunology ; Lymphocyte Activation ; Molecular Sequence Data ; Receptors, Antigen, T-Cell/immunology ; V(D)J Recombination/genetics
Czasopismo naukowe
Tytuł :
Stereoselective Synthesis of Carbon-Sulfur-Bridged Glycomimetics by Photoinitiated Thiol-Ene Coupling Reactions.
Autorzy :
Csávás M; Department of Pharmaceutical Chemistry University of Debrecen, Egyetem tér 1, H-4032 Debrecen, Hungary.
Eszenyi D; Department of Pharmaceutical Chemistry University of Debrecen, Egyetem tér 1, H-4032 Debrecen, Hungary.
Mező E; Department of Pharmaceutical Chemistry University of Debrecen, Egyetem tér 1, H-4032 Debrecen, Hungary.
Lázár L; Department of Organic Chemistry, University of Debrecen, Egyetem tér 1, H-4032 Debrecen, Hungary.
Debreczeni N; Department of Pharmaceutical Chemistry University of Debrecen, Egyetem tér 1, H-4032 Debrecen, Hungary.; Doctoral School of Chemistry, University of Debrecen, Egyetem tér 1, H-4032 Debrecen, Hungary.
Tóth M; Department of Organic Chemistry, University of Debrecen, Egyetem tér 1, H-4032 Debrecen, Hungary.
Somsák L; Department of Organic Chemistry, University of Debrecen, Egyetem tér 1, H-4032 Debrecen, Hungary.
Borbás A; Department of Pharmaceutical Chemistry University of Debrecen, Egyetem tér 1, H-4032 Debrecen, Hungary.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Jan 16; Vol. 21 (2). Date of Electronic Publication: 2020 Jan 16.
Typ publikacji :
Journal Article
MeSH Terms :
Carbon/*chemistry
Glycosides/*chemical synthesis
Glycosides/*chemistry
Oligosaccharides/*chemical synthesis
Oligosaccharides/*chemistry
Sulfhydryl Compounds/*chemistry
Sulfur/*chemistry
Molecular Sequence Data ; Stereoisomerism
Czasopismo naukowe
Tytuł :
Cyclic di-GMP-Mediated Regulation of Gene Transfer and Motility in Rhodobacter capsulatus.
Autorzy :
Pallegar P; Department of Biology, Memorial University of Newfoundland, St. John's, Newfoundland and Labrador, Canada.
Peña-Castillo L; Department of Biology, Memorial University of Newfoundland, St. John's, Newfoundland and Labrador, Canada.; Department of Computer Science, Memorial University of Newfoundland, St. John's, Newfoundland and Labrador, Canada.
Langille E; Department of Chemistry, Memorial University of Newfoundland, St. John's, Newfoundland and Labrador, Canada.
Gomelsky M; Department of Molecular Biology, University of Wyoming, Laramie, Wyoming, USA.
Lang AS; Department of Biology, Memorial University of Newfoundland, St. John's, Newfoundland and Labrador, Canada .
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Źródło :
Journal of bacteriology [J Bacteriol] 2020 Jan 02; Vol. 202 (2). Date of Electronic Publication: 2020 Jan 02 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cyclic GMP/*analogs & derivatives
Rhodobacter capsulatus/*metabolism
Amino Acid Sequence ; Bacterial Proteins/genetics ; Bacterial Proteins/metabolism ; Cyclic GMP/metabolism ; Escherichia coli Proteins/metabolism ; Gene Expression Regulation, Bacterial/drug effects ; Gene Transfer, Horizontal/drug effects ; Molecular Sequence Data ; Phosphoric Diester Hydrolases/genetics ; Phosphoric Diester Hydrolases/metabolism ; Phosphorus-Oxygen Lyases/metabolism ; Rhodobacter capsulatus/drug effects ; Signal Transduction/drug effects ; Signal Transduction/genetics
Czasopismo naukowe

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