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Wyszukujesz frazę ""Molecular Targeted Therapy"" wg kryterium: Temat


Tytuł :
Aurora B kinase: a potential drug target for cancer therapy.
Autorzy :
Ahmed A; Centre for Interdisciplinary Research in Basic Sciences, Jamia Millia Islamia, Jamia Nagar, New Delhi, 110025, India.
Shamsi A; Centre for Interdisciplinary Research in Basic Sciences, Jamia Millia Islamia, Jamia Nagar, New Delhi, 110025, India.
Mohammad T; Centre for Interdisciplinary Research in Basic Sciences, Jamia Millia Islamia, Jamia Nagar, New Delhi, 110025, India.
Hasan GM; Department of Biochemistry, College of Medicine, Prince Sattam Bin Abdulaziz University, P.O. Box 173, Al-Kharj, 11942, Kingdom of Saudi Arabia.
Islam A; Centre for Interdisciplinary Research in Basic Sciences, Jamia Millia Islamia, Jamia Nagar, New Delhi, 110025, India.
Hassan MI; Centre for Interdisciplinary Research in Basic Sciences, Jamia Millia Islamia, Jamia Nagar, New Delhi, 110025, India. .
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Źródło :
Journal of cancer research and clinical oncology [J Cancer Res Clin Oncol] 2021 Aug; Vol. 147 (8), pp. 2187-2198. Date of Electronic Publication: 2021 May 28.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Molecular Targeted Therapy*/methods
Molecular Targeted Therapy*/trends
Aurora Kinase B/*physiology
Neoplasms/*therapy
Animals ; Antineoplastic Agents/therapeutic use ; Aurora Kinase B/antagonists & inhibitors ; Aurora Kinase B/genetics ; Cell Cycle/genetics ; Chromosomes/genetics ; Chromosomes/metabolism ; Disease Progression ; Humans ; Mitosis/genetics ; Neoplasms/etiology ; Neoplasms/pathology
Czasopismo naukowe
Tytuł :
Angiogenesis and Anti-Angiogenic Treatment in Prostate Cancer: Mechanisms of Action and Molecular Targets.
Autorzy :
Ioannidou E; Department of Paediatrics and Child Health, Chelsea and Westminster Hospital, 369 Fulham Rd., London SW10 9NH, UK.
Moschetta M; CHUV, Lausanne University Hospital, Rue du Bugnon 21, CH-1011 Lausanne, Switzerland.
Shah S; Department of Medical Oncology, Medway NHS Foundation Trust, Windmill Road, Gillingham, Kent ME7 5NY, UK.
Parker JS; Department of Medical Oncology, Medway NHS Foundation Trust, Windmill Road, Gillingham, Kent ME7 5NY, UK.
Ozturk MA; Department of Medical Oncology, Sisli Memorial Hospital, Kaptan Paşa Mah. Piyale Paşa Bulv., Okmeydanı Cd. 4, Istanbul 34384, Turkey.
Pappas-Gogos G; Department of Surgery, University Hospital of Ioannina, 45111 Ioannina, Greece.
Sheriff M; Department of Urology, Medway NHS Foundation Trust, Windmill Road, Gillingham, Kent ME7 5NY, UK.
Rassy E; Department of Cancer Medicine, Gustave Roussy Institut, 94805 Villejuif, France.
Boussios S; Department of Medical Oncology, Medway NHS Foundation Trust, Windmill Road, Gillingham, Kent ME7 5NY, UK.; Faculty of Life Sciences & Medicine, School of Cancer & Pharmaceutical Sciences, King's College London, London SE1 9RT, UK.; AELIA Organization, 9th Km Thessaloniki, Thermi, 57001 Thessaloniki, Greece.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Sep 14; Vol. 22 (18). Date of Electronic Publication: 2021 Sep 14.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Molecular Targeted Therapy*
Angiogenesis Inhibitors/*therapeutic use
Neovascularization, Pathologic/*drug therapy
Prostatic Neoplasms/*blood supply
Prostatic Neoplasms/*drug therapy
Angiogenesis Inhibitors/pharmacology ; Animals ; Antineoplastic Agents/pharmacology ; Antineoplastic Agents/therapeutic use ; Drug Resistance, Neoplasm ; Humans ; Male
Czasopismo naukowe
Tytuł :
Targeted Therapy in the Treatment of Pediatric Acute Lymphoblastic Leukemia-Therapy and Toxicity Mechanisms.
Autorzy :
Lejman M; Laboratory of Genetic Diagnostics, Medical University of Lublin, A. Gębali 6, 20-093 Lublin, Poland.
Kuśmierczuk K; Student Scientific Society, Laboratory of Genetic Diagnostics, Medical University of Lublin, A. Gębali 6, 20-093 Lublin, Poland.
Bednarz K; Student Scientific Society, Laboratory of Genetic Diagnostics, Medical University of Lublin, A. Gębali 6, 20-093 Lublin, Poland.
Ostapińska K; Student Scientific Society, Laboratory of Genetic Diagnostics, Medical University of Lublin, A. Gębali 6, 20-093 Lublin, Poland.
Zawitkowska J; Department of Pediatric Hematology, Oncology and Transplantology, Medical University of Lublin, A. Gębali 6, 20-093 Lublin, Poland.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Sep 11; Vol. 22 (18). Date of Electronic Publication: 2021 Sep 11.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Drug Delivery Systems*
Immunotherapy*
Molecular Targeted Therapy*
Precision Medicine*
Antineoplastic Agents/*therapeutic use
Precursor Cell Lymphoblastic Leukemia-Lymphoma/*therapy
Adolescent ; Child ; Child, Preschool ; Female ; Humans ; Male
Czasopismo naukowe
Tytuł :
Molecular Network Approach Reveals Rictor as a Central Target of Cardiac ProtectomiRs.
Autorzy :
Makkos A; Cardiovascular and Metabolic Research Group, Department of Pharmacology and Pharmacotherapy, Semmelweis University, 1089 Budapest, Hungary.; MTA-SE System Pharmacology Research Group, Department of Pharmacology and Pharmacotherapy, Semmelweis University, 1089 Budapest, Hungary.
Ágg B; Cardiovascular and Metabolic Research Group, Department of Pharmacology and Pharmacotherapy, Semmelweis University, 1089 Budapest, Hungary.; MTA-SE System Pharmacology Research Group, Department of Pharmacology and Pharmacotherapy, Semmelweis University, 1089 Budapest, Hungary.; Pharmahungary Group, 6722 Szeged, Hungary.
Varga ZV; Cardiovascular and Metabolic Research Group, Department of Pharmacology and Pharmacotherapy, Semmelweis University, 1089 Budapest, Hungary.; HCEMM-SU Cardiometabolic Immunology Research Group, Department of Pharmacology and Pharmacotherapy, Semmelweis University, 1089 Budapest, Hungary.
Giricz Z; Cardiovascular and Metabolic Research Group, Department of Pharmacology and Pharmacotherapy, Semmelweis University, 1089 Budapest, Hungary.
Gyöngyösi M; Division of Cardiology, Medical University of Vienna, 1090 Vienna, Austria.
Lukovic D; Division of Cardiology, Medical University of Vienna, 1090 Vienna, Austria.
Schulz R; Institute of Physiology, Justus Liebig University Giessen, 35392 Giessen, Germany.
Barteková M; Institute for Heart Research, Centre of Experimental Medicine, Slovak Academy of Sciences, Dúbravská cesta 9, 84104 Bratislava, Slovakia.; Institute of Physiology, Comenius University in Bratislava, 81108 Bratislava, Slovakia.
Görbe A; Cardiovascular and Metabolic Research Group, Department of Pharmacology and Pharmacotherapy, Semmelweis University, 1089 Budapest, Hungary.; MTA-SE System Pharmacology Research Group, Department of Pharmacology and Pharmacotherapy, Semmelweis University, 1089 Budapest, Hungary.; Pharmahungary Group, 6722 Szeged, Hungary.
Ferdinandy P; Cardiovascular and Metabolic Research Group, Department of Pharmacology and Pharmacotherapy, Semmelweis University, 1089 Budapest, Hungary.; MTA-SE System Pharmacology Research Group, Department of Pharmacology and Pharmacotherapy, Semmelweis University, 1089 Budapest, Hungary.; Pharmahungary Group, 6722 Szeged, Hungary.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Sep 02; Vol. 22 (17). Date of Electronic Publication: 2021 Sep 02.
Typ publikacji :
Journal Article; Validation Study
MeSH Terms :
Molecular Targeted Therapy*
MicroRNAs/*metabolism
Myocardial Infarction/*metabolism
Rapamycin-Insensitive Companion of mTOR Protein/*metabolism
Animals ; Cardiotonic Agents ; Ischemic Postconditioning ; Ischemic Preconditioning, Myocardial ; Rats ; Swine
Czasopismo naukowe
Tytuł :
Immune-related adverse events: promising predictors for efficacy of immune checkpoint inhibitors.
Autorzy :
Zhong L; Department of Oncology, The First Affiliated Hospital of Fujian Medical University, No. 20 Chazhong Road, Taijiang District, Fuzhou, 350005, China.; Department of Oncology, The Second Hospital of Longyan, Fujian, 364000, China.
Wu Q; Department of Oncology, The First Affiliated Hospital of Fujian Medical University, No. 20 Chazhong Road, Taijiang District, Fuzhou, 350005, China.
Chen F; Department of Gynecology, The First Hospital of Longyan, Fujian, 364000, China.
Liu J; Department of Oncology, The First Affiliated Hospital of Fujian Medical University, No. 20 Chazhong Road, Taijiang District, Fuzhou, 350005, China.
Xie X; Department of Oncology, The First Affiliated Hospital of Fujian Medical University, No. 20 Chazhong Road, Taijiang District, Fuzhou, 350005, China. .; Molecular Oncology Research Institute, First Affiliated Hospital, Fujian Medical University, Fuzhou, 350005, China. .
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Źródło :
Cancer immunology, immunotherapy : CII [Cancer Immunol Immunother] 2021 Sep; Vol. 70 (9), pp. 2559-2576. Date of Electronic Publication: 2021 Feb 12.
Typ publikacji :
Journal Article; Meta-Analysis; Review
MeSH Terms :
Drug-Related Side Effects and Adverse Reactions/*etiology
Immune Checkpoint Inhibitors/*adverse effects
Molecular Targeted Therapy/*adverse effects
Neoplasms/*complications
Drug-Related Side Effects and Adverse Reactions/diagnosis ; Drug-Related Side Effects and Adverse Reactions/epidemiology ; Humans ; Immune Checkpoint Inhibitors/administration & dosage ; Immune Checkpoint Inhibitors/therapeutic use ; Incidence ; Molecular Targeted Therapy/methods ; Neoplasms/diagnosis ; Neoplasms/drug therapy ; Neoplasms/mortality ; Odds Ratio ; Prognosis ; Severity of Illness Index
Czasopismo naukowe
Tytuł :
Targeting key transcriptional factor STAT3 in colorectal cancer.
Autorzy :
Chalikonda G; Internal Medicine, University of Nevada, Reno, NV-89502, USA.
Lee H; NanoBio High-Tech Materials Research Center, Department of Biological Engineering, Inha University, Incheon, 22212, Republic of Korea.
Sheik A; NanoBio High-Tech Materials Research Center, Department of Biological Engineering, Inha University, Incheon, 22212, Republic of Korea. .
Huh YS; NanoBio High-Tech Materials Research Center, Department of Biological Engineering, Inha University, Incheon, 22212, Republic of Korea. .
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Źródło :
Molecular and cellular biochemistry [Mol Cell Biochem] 2021 Sep; Vol. 476 (9), pp. 3219-3228. Date of Electronic Publication: 2021 Apr 18.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Molecular Targeted Therapy*
Antineoplastic Agents/*therapeutic use
Colorectal Neoplasms/*drug therapy
STAT3 Transcription Factor/*antagonists & inhibitors
Animals ; Colorectal Neoplasms/metabolism ; Colorectal Neoplasms/pathology ; Humans
Czasopismo naukowe
Tytuł :
Druggable molecular alterations in bile duct cancer: potential and current therapeutic applications in clinical trials.
Autorzy :
Bourien H; Department Of Medical Oncology, Centre Eugène Marquis, Rennes, France, France.
Lamarca A; Department Of Medical Oncology, The Christie Nhs Foundation Trust/Division Of Cancer Sciences, University Of Manchester, Manchester, UK.
McNamara MG; Division Of Cancer Sciences, University Of Manchester/Department Of Medical Oncology, The Christie Nhs Foundation Trust, Manchester, UK.
Hubner RA; Department Of Medical Oncology, The Christie Nhs Foundation Trust/Division Of Cancer Sciences, University Of Manchester, Manchester, UK.
Valle JW; Division Of Cancer Sciences, University Of Manchester/Department Of Medical Oncology, The Christie Nhs Foundation Trust, Manchester, UK.
Edeline J; Department Of Medical Oncology, Centre Eugène Marquis, Rennes, France, France.
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Źródło :
Expert opinion on investigational drugs [Expert Opin Investig Drugs] 2021 Sep; Vol. 30 (9), pp. 975-983. Date of Electronic Publication: 2021 Aug 22.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Molecular Targeted Therapy*
Bile Duct Neoplasms/*drug therapy
Cholangiocarcinoma/*drug therapy
Animals ; Antineoplastic Agents/administration & dosage ; Antineoplastic Agents/pharmacology ; Bile Duct Neoplasms/pathology ; Cholangiocarcinoma/pathology ; Drug Development ; Drug Repositioning ; Humans ; Immunotherapy/methods ; Neoplasm Recurrence, Local ; Neoplasm Staging ; Precision Medicine
Czasopismo naukowe
Tytuł :
Identification of SLC38A7 as a Prognostic Marker and Potential Therapeutic Target of Lung Squamous Cell Carcinoma.
Autorzy :
Haratake N; Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Hu Q; Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Okamoto T; Department of Thoracic Oncology, National Hospital Organization Kyushu Cancer Center, Fukuoka, Japan.
Jogo T; Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.; Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Toyokawa G; Department of Thoracic Surgery, National Hospital Organization Kyushu Medical Center, Fukuoka, Japan.
Kinoshita F; Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Takenaka T; Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Tagawa T; Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Iseda N; Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Itoh S; Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Yamada Y; Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Oda Y; Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Shimokawa M; Division of Bioinformatics, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.
Kikutake C; Department of Biostatistics, Yamaguchi University Graduate School of Medicine, Yamaguchi, Japan.
Suyama M; Department of Biostatistics, Yamaguchi University Graduate School of Medicine, Yamaguchi, Japan.
Unoki M; Division of Epigenomics and Development, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.
Sasaki H; Division of Epigenomics and Development, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.
Mori M; Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
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Źródło :
Annals of surgery [Ann Surg] 2021 Sep 01; Vol. 274 (3), pp. 500-507.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Molecular Targeted Therapy*
Amino Acid Transport Systems/*genetics
Carcinoma, Squamous Cell/*genetics
Lung Neoplasms/*genetics
Aged ; Amino Acid Transport System A ; Carcinoma, Squamous Cell/mortality ; Carcinoma, Squamous Cell/surgery ; DNA Copy Number Variations ; Female ; Humans ; Lung Neoplasms/mortality ; Lung Neoplasms/surgery ; Male ; Middle Aged ; Oncogenes/genetics ; Prognosis ; RNA, Messenger/metabolism ; Retrospective Studies
Czasopismo naukowe
Tytuł :
Wnt/β-catenin signaling pathway in uterine leiomyoma: role in tumor biology and targeting opportunities.
Autorzy :
El Sabeh M; Department of Gynecology & Obstetrics, Johns Hopkins University School of Medicine, 720 Rutland Avenue, Baltimore, MD, 21205, USA.
Saha SK; Department of Gynecology & Obstetrics, Johns Hopkins University School of Medicine, 720 Rutland Avenue, Baltimore, MD, 21205, USA.
Afrin S; Department of Gynecology & Obstetrics, Johns Hopkins University School of Medicine, 720 Rutland Avenue, Baltimore, MD, 21205, USA.
Islam MS; Department of Gynecology & Obstetrics, Johns Hopkins University School of Medicine, 720 Rutland Avenue, Baltimore, MD, 21205, USA.
Borahay MA; Department of Gynecology & Obstetrics, Johns Hopkins University School of Medicine, 720 Rutland Avenue, Baltimore, MD, 21205, USA. .
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Źródło :
Molecular and cellular biochemistry [Mol Cell Biochem] 2021 Sep; Vol. 476 (9), pp. 3513-3536. Date of Electronic Publication: 2021 May 17.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Molecular Targeted Therapy*
Antineoplastic Agents/*therapeutic use
Leiomyoma/*drug therapy
Uterine Neoplasms/*drug therapy
Wnt Signaling Pathway/*drug effects
Animals ; Female ; Humans ; Leiomyoma/metabolism ; Leiomyoma/pathology ; Uterine Neoplasms/metabolism ; Uterine Neoplasms/pathology
Czasopismo naukowe
Tytuł :
Current updates on precision therapy for breast cancer associated brain metastasis: Emphasis on combination therapy.
Autorzy :
Raza M; Precision NeuroOncology & NeuroVascular Disease Modeling Group, Department of Life Sciences, School of Natural Sciences, Shiv Nadar University, Delhi NCR, India.
Kumar N; Precision NeuroOncology & NeuroVascular Disease Modeling Group, Department of Life Sciences, School of Natural Sciences, Shiv Nadar University, Delhi NCR, India.
Nair U; Department of Women's and Reproductive Health, Oxford Fertility, Oxford Business Park North, University of Oxford, Oxford, OX4 2HW, UK.
Luthra G; Precision NeuroOncology & NeuroVascular Disease Modeling Group, Department of Life Sciences, School of Natural Sciences, Shiv Nadar University, Delhi NCR, India.
Bhattacharyya U; Precision NeuroOncology & NeuroVascular Disease Modeling Group, Department of Life Sciences, School of Natural Sciences, Shiv Nadar University, Delhi NCR, India.
Jayasundar S; Precision NeuroOncology & NeuroVascular Disease Modeling Group, Department of Life Sciences, School of Natural Sciences, Shiv Nadar University, Delhi NCR, India.
Jayasundar R; Department of Nuclear Magnetic Resonance & MRI, All India Institute of Medical Sciences, New Delhi, 110029, India.
Sehrawat S; Precision NeuroOncology & NeuroVascular Disease Modeling Group, Department of Life Sciences, School of Natural Sciences, Shiv Nadar University, Delhi NCR, India. .
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Źródło :
Molecular and cellular biochemistry [Mol Cell Biochem] 2021 Sep; Vol. 476 (9), pp. 3271-3284. Date of Electronic Publication: 2021 Apr 22.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Molecular Targeted Therapy*
Precision Medicine*
Antineoplastic Agents/*therapeutic use
Brain Neoplasms/*drug therapy
Breast Neoplasms/*drug therapy
Receptor, ErbB-2/*antagonists & inhibitors
Animals ; Brain Neoplasms/metabolism ; Brain Neoplasms/secondary ; Breast Neoplasms/metabolism ; Breast Neoplasms/pathology ; Drug Therapy, Combination ; Female ; Humans
Czasopismo naukowe
Tytuł :
Imaging and treatment of brain tumors through molecular targeting: Recent clinical advances.
Autorzy :
Zaccagna F; Division of Neuroimaging, Department of Medical Imaging, University of Toronto, Toronto, Canada. Electronic address: .
Grist JT; Department of Physiology, Anatomy, and Genetics, University of Oxford, Oxford, United Kingdom; Oxford Centre for Clinical Magnetic Resonance Research, University of Oxford, Oxford, United Kingdom; Department of Radiology, Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom; Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, United Kingdom.
Quartuccio N; Nuclear Medicine Unit, A.R.N.A.S. Ospedali Civico Di Cristina Benfratelli, Palermo, Italy.
Riemer F; Mohn Medical Imaging and Visualization Centre, University of Bergen, Bergen, Norway; Department of Radiology, Haukeland University Hospital, Bergen, Norway.
Fraioli F; Institute of Nuclear Medicine, University College London, London, United Kingdom; NIHR University College London Hospitals Biomedical Research Centre, London, United Kingdom.
Caracò C; Department of Radiology, University of Cambridge, Cambridge, United Kingdom.
Halsey R; Institute of Nuclear Medicine, University College London, London, United Kingdom; NIHR University College London Hospitals Biomedical Research Centre, London, United Kingdom.
Aldalilah Y; Institute of Nuclear Medicine, University College London, London, United Kingdom; NIHR University College London Hospitals Biomedical Research Centre, London, United Kingdom; Department of Radiology, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
Cunningham CH; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada; Physical Sciences, Sunnybrook Research Institute, Toronto, Ontario, Canada.
Massoud TF; Division of Neuroimaging and Neurointervention, Department of Radiology, Stanford University School of Medicine, Stanford, USA.
Aloj L; Department of Radiology, University of Cambridge, Cambridge, United Kingdom; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, United Kingdom.
Gallagher FA; Department of Radiology, University of Cambridge, Cambridge, United Kingdom; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, United Kingdom.
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Źródło :
European journal of radiology [Eur J Radiol] 2021 Sep; Vol. 142, pp. 109842. Date of Electronic Publication: 2021 Jul 03.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Brain Neoplasms*/diagnostic imaging
Brain Neoplasms*/therapy
Molecular Targeted Therapy*
Humans ; Magnetic Resonance Imaging ; Positron-Emission Tomography ; Tomography, X-Ray Computed
Czasopismo naukowe
Tytuł :
A-FABP in Metabolic Diseases and the Therapeutic Implications: An Update.
Autorzy :
Li HL; Division of Clinical Pharmacology and Therapeutics, Department of Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong 999077, China.
Wu X; Department of Pharmacology and Pharmacy, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong 999077, China.; State Key Laboratory of Pharmaceutical Biotechnology, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong 999077, China.
Xu A; Division of Clinical Pharmacology and Therapeutics, Department of Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong 999077, China.; Department of Pharmacology and Pharmacy, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong 999077, China.; State Key Laboratory of Pharmaceutical Biotechnology, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong 999077, China.
Hoo RL; Department of Pharmacology and Pharmacy, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong 999077, China.; State Key Laboratory of Pharmaceutical Biotechnology, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong 999077, China.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Aug 30; Vol. 22 (17). Date of Electronic Publication: 2021 Aug 30.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Molecular Targeted Therapy*
Fatty Acid-Binding Proteins/*metabolism
Metabolic Diseases/*pathology
Animals ; Fatty Acid-Binding Proteins/genetics ; Humans ; Metabolic Diseases/genetics ; Metabolic Diseases/metabolism
Czasopismo naukowe
Tytuł :
Classification and Treatment of Diseases in the Age of Genome Medicine Based on Pathway Pathology.
Autorzy :
Petersen I; Institute of Pathology, SRH Poliklinik Gera, SRH-Wald-Klinikum Gera, Strasse des Friedens 122, D-07548 Gera, Germany.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Aug 30; Vol. 22 (17). Date of Electronic Publication: 2021 Aug 30.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Genome, Human*
Molecular Targeted Therapy*
Precision Medicine*
Signal Transduction*
Disease/*genetics
Humans
Czasopismo naukowe
Tytuł :
The Role of Noncoding RNA in the Pathophysiology and Treatment of Premature Ovarian Insufficiency.
Autorzy :
Pankiewicz K; Department of Obstetrics and Gynecology, Institute of Mother and Child in Warsaw, Kasprzaka 17a, 01-211 Warsaw, Poland.
Laudański P; 1st Department of Obstetrics and Gynecology, Medical University of Warsaw, Starynkiewicza 1/3, 02-015 Warsaw, Poland.; OVIklinika Infertility Center, Połczyńska 31, 01-377 Warsaw, Poland.
Issat T; Department of Obstetrics and Gynecology, Institute of Mother and Child in Warsaw, Kasprzaka 17a, 01-211 Warsaw, Poland.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Aug 28; Vol. 22 (17). Date of Electronic Publication: 2021 Aug 28.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Molecular Targeted Therapy*
Primary Ovarian Insufficiency/*physiopathology
Primary Ovarian Insufficiency/*therapy
RNA, Untranslated/*genetics
Female ; Humans ; Primary Ovarian Insufficiency/genetics ; Primary Ovarian Insufficiency/pathology
Czasopismo naukowe
Tytuł :
TRP channels in COVID-19 disease: Potential targets for prevention and treatment.
Autorzy :
Jaffal SM; Department of Biological Sciences, Faculty of Science, The University of Jordan, 11942, Amman, Jordan. Electronic address: .
Abbas MA; Department of Medical Laboratory Sciences, Faculty of Allied Medical Sciences, Al-Ahliyya Amman University, 19328, Amman, Jordan; Pharmacological and Diagnostic Research Center, Al-Ahliyya Amman University, 19328, Amman, Jordan.
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Źródło :
Chemico-biological interactions [Chem Biol Interact] 2021 Aug 25; Vol. 345, pp. 109567. Date of Electronic Publication: 2021 Jun 22.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Molecular Targeted Therapy*
COVID-19/*drug therapy
COVID-19/*prevention & control
Transient Receptor Potential Channels/*metabolism
COVID-19/metabolism ; Humans
Czasopismo naukowe
Tytuł :
The anti-inflammatory effect of ε-viniferin by specifically targeting formyl peptide receptor 1 on human neutrophils.
Autorzy :
Liao HR; Graduate Institute of Natural Products, College of Medicine, Chang-Gung University, Tao Yuan, Taiwan, Republic of China; Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Kwei-Shan, Taoyuan, 333, Taiwan, Republic of China; Department of Anesthesiology, Chang Gung Memorial Hospital, Linkou, Taiwan, Republic of China. Electronic address: .
Lin CH; Graduate Institute of Natural Products, College of Medicine, Chang-Gung University, Tao Yuan, Taiwan, Republic of China.
Chen JJ; Faculty of Pharmacy, School of Pharmaceutical Sciences, National Yang-Ming University, Taipei, Taiwan, Republic of China; Department of Medical Research, China Medical University Hospital, China Medical University, Taichung, Taiwan, Republic of China.
Liu FC; Department of Anesthesiology, Chang Gung Memorial Hospital, Linkou, Taiwan, Republic of China.
Tseng CP; Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Kwei-Shan, Taoyuan, 333, Taiwan, Republic of China; Department of Medical Biotechnology and Laboratory Science, College of Medicine, Chang Gung University, Kwei Shan, Taoyuan, 333, Taiwan, Republic of China; Molecular Medicine Research Center, Chang Gung University, Kwei Shan, Taoyuan, 333, Taiwan, Republic of China; Department of Laboratory Medicine, Chang Gung Memorial Hospital, Kwei Shan, Taoyuan, 333, Taiwan, Republic of China.
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Źródło :
Chemico-biological interactions [Chem Biol Interact] 2021 Aug 25; Vol. 345, pp. 109490. Date of Electronic Publication: 2021 Jun 16.
Typ publikacji :
Journal Article
MeSH Terms :
Molecular Targeted Therapy*
Anti-Inflammatory Agents/*pharmacology
Benzofurans/*pharmacology
Neutrophils/*drug effects
Neutrophils/*metabolism
Receptors, Formyl Peptide/*antagonists & inhibitors
Stilbenes/*pharmacology
Amino Acid Sequence ; Calcium/metabolism ; Dose-Response Relationship, Drug ; Drug Synergism ; Humans ; Oligopeptides/chemistry ; Oligopeptides/pharmacology ; Superoxides/metabolism
Czasopismo naukowe
Tytuł :
Genetic Variants and Tumor Immune Microenvironment: Clues for Targeted Therapies in Inflammatory Breast Cancer (IBC).
Autorzy :
Gong Y; Fox Chase Cancer Center, Philadelphia, PA 19111, USA.
Nagarathinam R; Fox Chase Cancer Center, Philadelphia, PA 19111, USA.
Arisi MF; Department of Pathology, Thomas Jefferson University, Philadelphia, PA 19107, USA.
Gerratana L; Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
Winn JS; Fox Chase Cancer Center, Philadelphia, PA 19111, USA.
Slifker M; Fox Chase Cancer Center, Philadelphia, PA 19111, USA.
Pei J; Fox Chase Cancer Center, Philadelphia, PA 19111, USA.
Cai KQ; Fox Chase Cancer Center, Philadelphia, PA 19111, USA.
Hasse Z; Fox Chase Cancer Center, Philadelphia, PA 19111, USA.
Obeid E; Fox Chase Cancer Center, Philadelphia, PA 19111, USA.
Noriega J; Fox Chase Cancer Center, Philadelphia, PA 19111, USA.
Sebastiano C; Department of Pathology, Thomas Jefferson University, Philadelphia, PA 19107, USA.
Ross E; Fox Chase Cancer Center, Philadelphia, PA 19111, USA.
Alpaugh K; Fox Chase Cancer Center, Philadelphia, PA 19111, USA.
Cristofanilli M; Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
Fernandez SV; Fox Chase Cancer Center, Philadelphia, PA 19111, USA.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Aug 19; Vol. 22 (16). Date of Electronic Publication: 2021 Aug 19.
Typ publikacji :
Journal Article
MeSH Terms :
Molecular Targeted Therapy*
Mutation*
Biomarkers, Tumor/*genetics
Cell-Free Nucleic Acids/*genetics
Inflammatory Breast Neoplasms/*pathology
Lymphocytes, Tumor-Infiltrating/*immunology
Tumor Microenvironment/*immunology
Adult ; Aged ; B7-H1 Antigen/genetics ; B7-H1 Antigen/metabolism ; Cell-Free Nucleic Acids/analysis ; Female ; Follow-Up Studies ; Gene Expression Regulation, Neoplastic ; High-Throughput Nucleotide Sequencing ; Humans ; Inflammatory Breast Neoplasms/genetics ; Inflammatory Breast Neoplasms/immunology ; Middle Aged ; Prognosis ; Receptor, ErbB-2/metabolism ; Receptors, Estrogen/metabolism ; Receptors, Progesterone/metabolism ; Retrospective Studies ; Survival Rate
Czasopismo naukowe
Tytuł :
Breast Cancer Targeting of a Drug Delivery System through Postsynthetic Modification of Curcumin@N 3 -bio-MOF-100 via Click Chemistry.
Autorzy :
Alves RC; Department of Drugs and Medicines, School of Pharmaceutical Sciences of São Paulo State University (UNESP), Rodovia Araraquara Jaú, Km 01 - s/n - Campos Ville, 14800-903 Araraquara, São Paulo, Brazil.
Schulte ZM; Department of Chemistry, University of Pittsburgh, 219 Parkman Avenue, Pittsburgh, Pennsylvania 1560, United States.
Luiz MT; Department of Pharmaceutical Sciences, School of Pharmaceutical Science of Ribeirão Preto, University of São Paulo (USP), Avenida do Café, s/n - Campus da USP, 14040-903 Ribeirão Preto, Sao Paulo, Brazil.
Bento da Silva P; Department of Genetics and Morphology, Institute of Biological Sciences, University of Brasilia (UnB), Campus Universitario Darcy Ribeiro - Asa Norte, 70910-900 Brasilia, Federal District, Brazil.
Frem RCG; Institute of Chemistry, São Paulo State University (UNESP), Prof. Francisco Degni 55, PO Box 355, 14800-970 Araraquara, São Paulo, Brazil.
Rosi NL; Department of Chemistry, University of Pittsburgh, 219 Parkman Avenue, Pittsburgh, Pennsylvania 1560, United States.
Chorilli M; Department of Drugs and Medicines, School of Pharmaceutical Sciences of São Paulo State University (UNESP), Rodovia Araraquara Jaú, Km 01 - s/n - Campos Ville, 14800-903 Araraquara, São Paulo, Brazil.
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Źródło :
Inorganic chemistry [Inorg Chem] 2021 Aug 16; Vol. 60 (16), pp. 11739-11744. Date of Electronic Publication: 2021 Jun 08.
Typ publikacji :
Journal Article
MeSH Terms :
Molecular Targeted Therapy*
Breast Neoplasms/*drug therapy
Curcumin/*chemistry
Drug Carriers/*chemistry
Metal-Organic Frameworks/*chemistry
Click Chemistry ; Curcumin/pharmacology ; Curcumin/therapeutic use ; Folic Acid/chemistry
Czasopismo naukowe
Tytuł :
Insights on Metabolic Reprogramming and Its Therapeutic Potential in Acute Leukemia.
Autorzy :
Di Martino L; Dipartimento di Scienze Chirurgiche, Oncologiche e Gastroenterologiche, Universita' di Padova, 35122 Padova, Italy.
Tosello V; UOC Immunologia e Diagnostica Molecolare Oncologica, Istituto Oncologico Veneto IOV-IRCCS, 35128 Padova, Italy.
Peroni E; UOC Immunologia e Diagnostica Molecolare Oncologica, Istituto Oncologico Veneto IOV-IRCCS, 35128 Padova, Italy.
Piovan E; Dipartimento di Scienze Chirurgiche, Oncologiche e Gastroenterologiche, Universita' di Padova, 35122 Padova, Italy.; UOC Immunologia e Diagnostica Molecolare Oncologica, Istituto Oncologico Veneto IOV-IRCCS, 35128 Padova, Italy.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Aug 14; Vol. 22 (16). Date of Electronic Publication: 2021 Aug 14.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Molecular Targeted Therapy*
Antineoplastic Agents/*therapeutic use
Leukemia, Myeloid, Acute/*drug therapy
Precursor Cell Lymphoblastic Leukemia-Lymphoma/*drug therapy
Adolescent ; Humans ; Leukemia, Myeloid, Acute/metabolism ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/metabolism ; Treatment Outcome ; Young Adult
Czasopismo naukowe
Tytuł :
Targeted and Non-Targeted Mechanisms for Killing Hypoxic Tumour Cells-Are There New Avenues for Treatment?
Autorzy :
Apilan AG; Department of Biology, McMaster University, Hamilton, ON L8S 4L8, Canada.
Mothersill C; Department of Biology, McMaster University, Hamilton, ON L8S 4L8, Canada.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Aug 11; Vol. 22 (16). Date of Electronic Publication: 2021 Aug 11.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Molecular Targeted Therapy/*methods
Neoplasms/*therapy
Tumor Hypoxia/*physiology
Animals ; Antineoplastic Agents/pharmacology ; Antineoplastic Agents/therapeutic use ; Cell Death ; Humans ; Molecular Targeted Therapy/trends ; Neoplasms/pathology ; Prodrugs/pharmacology ; Prodrugs/therapeutic use ; Radiation-Sensitizing Agents/pharmacology ; Radiation-Sensitizing Agents/therapeutic use ; Therapies, Investigational/methods ; Therapies, Investigational/trends
Czasopismo naukowe

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