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Tytuł :
Functional communication between IP 3 R and STIM2 at subthreshold stimuli is a critical checkpoint for initiation of SOCE.
Autorzy :
Ahmad M; Secretory Physiology Section, National Institute of Dental and Craniofacial Research, NIH, Bethesda, MD 20892.
Ong HL; Secretory Physiology Section, National Institute of Dental and Craniofacial Research, NIH, Bethesda, MD 20892.
Saadi H; Secretory Physiology Section, National Institute of Dental and Craniofacial Research, NIH, Bethesda, MD 20892.
Son GY; Secretory Physiology Section, National Institute of Dental and Craniofacial Research, NIH, Bethesda, MD 20892.
Shokatian Z; Secretory Physiology Section, National Institute of Dental and Craniofacial Research, NIH, Bethesda, MD 20892.
Terry LE; Department of Pharmacology and Physiology, University of Rochester, Rochester, NY 14526.
Trebak M; Department of Pharmacology and Chemical Biology, Vascular Medicine Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261.
Yule DI; Department of Pharmacology and Physiology, University of Rochester, Rochester, NY 14526.
Ambudkar I; Secretory Physiology Section, National Institute of Dental and Craniofacial Research, NIH, Bethesda, MD 20892; .
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2022 Jan 18; Vol. 119 (3).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Inositol 1,4,5-Trisphosphate Receptors/*chemistry
Inositol 1,4,5-Trisphosphate Receptors/*metabolism
Stromal Interaction Molecule 2/*chemistry
Stromal Interaction Molecule 2/*metabolism
Calcium/metabolism ; Calcium Signaling/physiology ; Cell Membrane/metabolism ; Cluster Analysis ; Endoplasmic Reticulum/metabolism ; HEK293 Cells ; Humans ; Inositol 1,4,5-Trisphosphate Receptors/genetics ; Neoplasm Proteins ; Stromal Interaction Molecule 1 ; Stromal Interaction Molecule 2/genetics
Czasopismo naukowe
Tytuł :
Bidirectional regulation of calcium release-activated calcium (CRAC) channel by SARAF.
Autorzy :
Zomot E; Department of Biochemistry, Ruth and Bruce Rappaport Faculty of Medicine, Technion - Israel Institute of Technology, Haifa, Israel.
Achildiev Cohen H; Department of Biochemistry, Ruth and Bruce Rappaport Faculty of Medicine, Technion - Israel Institute of Technology, Haifa, Israel.
Dagan I; Department of Biochemistry, Ruth and Bruce Rappaport Faculty of Medicine, Technion - Israel Institute of Technology, Haifa, Israel.
Militsin R; Department of Biochemistry, Ruth and Bruce Rappaport Faculty of Medicine, Technion - Israel Institute of Technology, Haifa, Israel.
Palty R; Department of Biochemistry, Technion Integrated Cancer Center, Ruth and Bruce Rappaport Faculty of Medicine, Technion - Israel Institute of Technology, Haifa, Israel.
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Źródło :
The Journal of cell biology [J Cell Biol] 2021 Dec 06; Vol. 220 (12). Date of Electronic Publication: 2021 Oct 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Calcium Release Activated Calcium Channels/*metabolism
Intracellular Calcium-Sensing Proteins/*metabolism
Membrane Proteins/*metabolism
ORAI1 Protein/*metabolism
Stromal Interaction Molecule 1/*metabolism
Calcium/metabolism ; HEK293 Cells ; Humans ; Ion Channel Gating ; Jurkat Cells ; NFATC Transcription Factors/metabolism ; Protein Binding ; Protein Conformation ; Stromal Interaction Molecule 1/chemistry ; Stromal Interaction Molecule 2/metabolism ; Transcription, Genetic
Czasopismo naukowe
Tytuł :
Discovery of potent BET bromodomain 1 stereoselective inhibitors using DNA-encoded chemical library selections.
Autorzy :
Modukuri RK; Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030.
Yu Z; Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030.
Tan Z; Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030.
Ta HM; Department of Pharmacology and Chemical Biology, Baylor College of Medicine, Houston, TX 77030.
Ucisik MN; Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030.
Jin Z; Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030.
Anglin JL; Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030.
Sharma KL; Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030.
Nyshadham P; Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030.
Li F; Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030.; Department of Pharmacology and Chemical Biology, Baylor College of Medicine, Houston, TX 77030.
Riehle K; Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030.
Faver JC; Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030.
Duong K; Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030.; Department of Pediatrics, Texas Children's Hospital, Baylor College of Medicine, Houston, TX 77030.
Nagarajan S; Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030.
Simmons N; Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030.
Palmer SS; Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030.
Teng M; Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030.; Department of Pharmacology and Chemical Biology, Baylor College of Medicine, Houston, TX 77030.
Young DW; Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030.; Department of Pharmacology and Chemical Biology, Baylor College of Medicine, Houston, TX 77030.
Yi JS; Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030.; Department of Pediatrics, Texas Children's Hospital, Baylor College of Medicine, Houston, TX 77030.
Kim C; Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030.; Department of Pharmacology and Chemical Biology, Baylor College of Medicine, Houston, TX 77030.
Matzuk MM; Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030.; Department of Pharmacology and Chemical Biology, Baylor College of Medicine, Houston, TX 77030.
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2022 May 31; Vol. 119 (22), pp. e2122506119. Date of Electronic Publication: 2022 May 27.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Inflammatory Agents, Non-Steroidal*/chemistry
Anti-Inflammatory Agents, Non-Steroidal*/isolation & purification
Anti-Inflammatory Agents, Non-Steroidal*/pharmacology
Antineoplastic Agents*/chemistry
Antineoplastic Agents*/isolation & purification
Antineoplastic Agents*/pharmacology
Contraceptive Agents, Male*/chemistry
Contraceptive Agents, Male*/isolation & purification
Contraceptive Agents, Male*/pharmacology
Drug Discovery*
Nuclear Proteins*/antagonists & inhibitors
Nuclear Proteins*/chemistry
Small Molecule Libraries*/chemistry
Small Molecule Libraries*/isolation & purification
Small Molecule Libraries*/pharmacology
DNA/genetics ; Humans ; Male ; Protein Domains ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Small Molecule Agents Targeting PD-1 Checkpoint Pathway for Cancer Immunotherapy: Mechanisms of Action and Other Considerations for Their Advanced Development.
Autorzy :
Sasikumar PG; Aurigene Discovery Technologies Limited, Bangalore, India.
Ramachandra M; Aurigene Discovery Technologies Limited, Bangalore, India.
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Źródło :
Frontiers in immunology [Front Immunol] 2022 May 02; Vol. 13, pp. 752065. Date of Electronic Publication: 2022 May 02 (Print Publication: 2022).
Typ publikacji :
Journal Article; Review
MeSH Terms :
B7-H1 Antigen*/antagonists & inhibitors
B7-H1 Antigen*/immunology
Immune Checkpoint Inhibitors*/pharmacology
Neoplasms*
Programmed Cell Death 1 Receptor*
Small Molecule Libraries*/pharmacology
Animals ; Antibodies ; Humans ; Immunotherapy ; Randomized Controlled Trials as Topic
Czasopismo naukowe
Tytuł :
Imaging Minimal Bacteria at the Nanoscale: a Reliable and Versatile Process to Perform Single-Molecule Localization Microscopy in Mycoplasmas.
Autorzy :
Rideau F; Université de Bordeaux, INRAE, Biologie du Fruit et Pathologie, UMR 1332, Villenave d'Ornon, France.
Villa A; Université de Bordeaux, INRAE, Biologie du Fruit et Pathologie, UMR 1332, Villenave d'Ornon, France.
Belzanne P; Interdisciplinary Institute for Neuroscience, CNRS, Université de Bordeaux, IINS, UMR 5297, Bordeaux, France.
Verdier E; Interdisciplinary Institute for Neuroscience, CNRS, Université de Bordeaux, IINS, UMR 5297, Bordeaux, France.
Hosy E; Interdisciplinary Institute for Neuroscience, CNRS, Université de Bordeaux, IINS, UMR 5297, Bordeaux, France.
Arfi Y; Université de Bordeaux, INRAE, Biologie du Fruit et Pathologie, UMR 1332, Villenave d'Ornon, France.
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Źródło :
Microbiology spectrum [Microbiol Spectr] 2022 Jun 29; Vol. 10 (3), pp. e0064522. Date of Electronic Publication: 2022 May 31.
Typ publikacji :
Journal Article
MeSH Terms :
Mycoplasma*/genetics
Single Molecule Imaging*
Fluorescent Dyes ; Humans ; Microscopy
Czasopismo naukowe
Tytuł :
Small-molecule modulators of protein-RNA interactions.
Autorzy :
Byun WG; CRI Center for Chemical Proteomics, Department of Chemistry, Seoul National University, Seoul, 08826, Korea(South).
Lim D; School of Biopharmaceutical and Medical Sciences, Sungshin University, Seoul, 01133, Korea(South).
Park SB; CRI Center for Chemical Proteomics, Department of Chemistry, Seoul National University, Seoul, 08826, Korea(South). Electronic address: .
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Źródło :
Current opinion in chemical biology [Curr Opin Chem Biol] 2022 Jun; Vol. 68, pp. 102149. Date of Electronic Publication: 2022 May 06.
Typ publikacji :
Journal Article; Review
MeSH Terms :
RNA-Binding Proteins*
Small Molecule Libraries*/pharmacology
Humans
Czasopismo naukowe
Tytuł :
Chemoinformatic Characterization of Synthetic Screening Libraries Focused on Epigenetic Targets.
Autorzy :
Flores-Padilla EA; DIFACQUIM Research Group, Department of Pharmacy, National Autonomous University of Mexico, Mexico City, 04510, Mexico.
Juárez-Mercado KE; DIFACQUIM Research Group, Department of Pharmacy, National Autonomous University of Mexico, Mexico City, 04510, Mexico.
Naveja JJ; Instituto de Quimica, National Autonomous University of Mexico, Mexico City, 04510, Mexico.
Kim TD; Department of Chemistry, University of Florida, Gainesville, Florida, 32611, United States.
Alain Miranda-Quintana R; Department of Chemistry, University of Florida, Gainesville, Florida, 32611, United States.; Quantum Theory Project, University of Florida, Gainesville, Florida, 32611, United States.
Medina-Franco JL; DIFACQUIM Research Group, Department of Pharmacy, National Autonomous University of Mexico, Mexico City, 04510, Mexico.
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Źródło :
Molecular informatics [Mol Inform] 2022 Jun; Vol. 41 (6), pp. e2100285. Date of Electronic Publication: 2021 Dec 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cheminformatics*
Small Molecule Libraries*/chemistry
Small Molecule Libraries*/pharmacology
Epigenesis, Genetic
Czasopismo naukowe
Tytuł :
Biophysical Survey of Small-Molecule β-Catenin Inhibitors: A Cautionary Tale.
Autorzy :
McCoy MA; School of Chemistry, University of Southampton, Southampton SO17 1BJ, U.K.
Spicer D; School of Chemistry, University of Southampton, Southampton SO17 1BJ, U.K.
Wells N; School of Chemistry, University of Southampton, Southampton SO17 1BJ, U.K.
Hoogewijs K; National University of Ireland, University Road, Galway H91 TK33, Ireland.
Fiedler M; Medical Research Council, Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH, U.K.
Baud MGJ; School of Chemistry, University of Southampton, Southampton SO17 1BJ, U.K.
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Źródło :
Journal of medicinal chemistry [J Med Chem] 2022 May 26; Vol. 65 (10), pp. 7246-7261. Date of Electronic Publication: 2022 May 17.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Small Molecule Libraries*/chemistry
Small Molecule Libraries*/pharmacology
Wnt Signaling Pathway*
beta Catenin*
Animals ; Biophysical Phenomena ; Drug Discovery ; Humans
Czasopismo naukowe
Tytuł :
Machine Learning on DNA-Encoded Library Count Data Using an Uncertainty-Aware Probabilistic Loss Function.
Autorzy :
Lim KS; Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States.; Department of Biology, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States.
Reidenbach AG; Chemical Biology and Therapeutics Science Program, Broad Institute, 415 Main Street, Cambridge, Massachusetts 02142, United States.
Hua BK; Chemical Biology and Therapeutics Science Program, Broad Institute, 415 Main Street, Cambridge, Massachusetts 02142, United States.; Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, Massachusetts 02138, United States.
Mason JW; Chemical Biology and Therapeutics Science Program, Broad Institute, 415 Main Street, Cambridge, Massachusetts 02142, United States.; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, United States.
Gerry CJ; Chemical Biology and Therapeutics Science Program, Broad Institute, 415 Main Street, Cambridge, Massachusetts 02142, United States.; Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, Massachusetts 02138, United States.
Clemons PA; Chemical Biology and Therapeutics Science Program, Broad Institute, 415 Main Street, Cambridge, Massachusetts 02142, United States.
Coley CW; Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States.; Chemical Biology and Therapeutics Science Program, Broad Institute, 415 Main Street, Cambridge, Massachusetts 02142, United States.; Department of Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States.
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Źródło :
Journal of chemical information and modeling [J Chem Inf Model] 2022 May 23; Vol. 62 (10), pp. 2316-2331. Date of Electronic Publication: 2022 May 10.
Typ publikacji :
Journal Article; Review
MeSH Terms :
DNA*/chemistry
Small Molecule Libraries*/chemistry
Small Molecule Libraries*/pharmacology
Drug Discovery/methods ; Machine Learning ; Uncertainty
Czasopismo naukowe
Tytuł :
Exploration of Ultralarge Compound Collections for Drug Discovery.
Autorzy :
Warr WA; Wendy Warr & Associates, 6 Berwick Court, Holmes Chapel, Crewe, Cheshire CW4 7HZ, United Kingdom.
Nicklaus MC; NCI, NIH, CADD Group, NCI-Frederick, Frederick, Maryland 21702, United States.
Nicolaou CA; Discovery Chemistry, Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana 46285, United States.
Rarey M; Universität Hamburg, ZBH Center for Bioinformatics, 20146 Hamburg, Germany.
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Źródło :
Journal of chemical information and modeling [J Chem Inf Model] 2022 May 09; Vol. 62 (9), pp. 2021-2034. Date of Electronic Publication: 2022 Apr 14.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Drug Discovery*/methods
Small Molecule Libraries*/chemistry
Small Molecule Libraries*/pharmacology
Drug Design
Czasopismo naukowe
Tytuł :
Super-Resolution Microscopy for Structural Cell Biology.
Autorzy :
Liu S; Cell Biology & Biophysics Unit, European Molecular Biology Laboratory, Heidelberg, Germany; email: .
Hoess P; Cell Biology & Biophysics Unit, European Molecular Biology Laboratory, Heidelberg, Germany; email: .
Ries J; Cell Biology & Biophysics Unit, European Molecular Biology Laboratory, Heidelberg, Germany; email: .
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Źródło :
Annual review of biophysics [Annu Rev Biophys] 2022 May 09; Vol. 51, pp. 301-326. Date of Electronic Publication: 2022 Feb 04.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Single Molecule Imaging*/methods
Microscopy, Electron
Czasopismo naukowe
Tytuł :
Axon-dendrite and apical-basolateral sorting in a single neuron.
Autorzy :
Lillis M; Department of Genetics, Blavatnik Institute, Harvard Medical School and Boston Children's Hospital, Boston, MA 02115, USA.
Zaccardi NJ; Department of Genetics, Blavatnik Institute, Harvard Medical School and Boston Children's Hospital, Boston, MA 02115, USA.
Heiman MG; Department of Genetics, Blavatnik Institute, Harvard Medical School and Boston Children's Hospital, Boston, MA 02115, USA.
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Źródło :
Genetics [Genetics] 2022 May 05; Vol. 221 (1).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Dendrites*/metabolism
Neural Cell Adhesion Molecule L1*/genetics
Neural Cell Adhesion Molecule L1*/metabolism
Animals ; Axons/metabolism ; Caenorhabditis elegans/genetics ; Caenorhabditis elegans/metabolism ; Humans ; Mammals ; Neurons/metabolism
Czasopismo naukowe
Tytuł :
L1 cell adhesion molecule high expression is associated with poor prognosis in surgically resected brain metastases from lung adenocarcinoma.
Autorzy :
Wang JW; Department of Neurosurgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, PR China.
Wang SQ; Department of Neurosurgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, PR China.
Wu ZY; Department of Neurosurgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, PR China.
Liu Q; Department of Neurosurgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, PR China.
Yuan Q; Department of Neurosurgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, PR China. Electronic address: .
Cai HQ; Department of Neurosurgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, PR China. Electronic address: .
Wan JH; Department of Neurosurgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, PR China. Electronic address: .
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Źródło :
Clinics (Sao Paulo, Brazil) [Clinics (Sao Paulo)] 2022 May 04; Vol. 77, pp. 100040. Date of Electronic Publication: 2022 May 04 (Print Publication: 2022).
Typ publikacji :
Journal Article
MeSH Terms :
Adenocarcinoma of Lung*/metabolism
Adenocarcinoma of Lung*/pathology
Adenocarcinoma of Lung*/surgery
Brain Neoplasms*/metabolism
Brain Neoplasms*/secondary
Brain Neoplasms*/surgery
Lung Neoplasms*/metabolism
Lung Neoplasms*/pathology
Lung Neoplasms*/surgery
Neural Cell Adhesion Molecule L1*/biosynthesis
Biomarkers, Tumor ; Humans ; Prognosis
Czasopismo naukowe
Tytuł :
Puckering the Planar Landscape of Fragments: Design and Synthesis of a 3D Cyclobutane Fragment Library.
Autorzy :
Hamilton DJ; Amsterdam Institute of Molecular and Life Sciences (AIMMS), Vrije Universiteit Amsterdam, De Boelelaan 1108, 1081 HZ, Amsterdam, The Netherlands.
Beemsterboer M; Amsterdam Institute of Molecular and Life Sciences (AIMMS), Vrije Universiteit Amsterdam, De Boelelaan 1108, 1081 HZ, Amsterdam, The Netherlands.
Carter CM; Amsterdam Institute of Molecular and Life Sciences (AIMMS), Vrije Universiteit Amsterdam, De Boelelaan 1108, 1081 HZ, Amsterdam, The Netherlands.
Elsayed J; Amsterdam Institute of Molecular and Life Sciences (AIMMS), Vrije Universiteit Amsterdam, De Boelelaan 1108, 1081 HZ, Amsterdam, The Netherlands.
Huiberts REM; Amsterdam Institute of Molecular and Life Sciences (AIMMS), Vrije Universiteit Amsterdam, De Boelelaan 1108, 1081 HZ, Amsterdam, The Netherlands.
Klein HF; Department of Chemistry, University of York, YO10 5DD, York, UK.
O'Brien P; Department of Chemistry, University of York, YO10 5DD, York, UK.
de Esch IJP; Amsterdam Institute of Molecular and Life Sciences (AIMMS), Vrije Universiteit Amsterdam, De Boelelaan 1108, 1081 HZ, Amsterdam, The Netherlands.
Wijtmans M; Amsterdam Institute of Molecular and Life Sciences (AIMMS), Vrije Universiteit Amsterdam, De Boelelaan 1108, 1081 HZ, Amsterdam, The Netherlands.
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Źródło :
ChemMedChem [ChemMedChem] 2022 May 04; Vol. 17 (9), pp. e202200113. Date of Electronic Publication: 2022 Mar 30.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cyclobutanes*
Small Molecule Libraries*/chemistry
Small Molecule Libraries*/pharmacology
Drug Design ; Drug Discovery/methods
Czasopismo naukowe
Tytuł :
Artemisinin upregulates neural cell adhesion molecule L1 to attenuate neurological deficits after intracerebral hemorrhage in mice.
Autorzy :
Wang J; Department of Neurosurgery, General Hospital of Xinjiang Military Region, Urumqi, China.
Yin J; Department of Neurosurgery, General Hospital of Xinjiang Military Region, Urumqi, China.
Zheng X; Department of Neurosurgery, General Hospital of Xinjiang Military Region, Urumqi, China.
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Źródło :
Brain and behavior [Brain Behav] 2022 May; Vol. 12 (5), pp. e2558. Date of Electronic Publication: 2022 Mar 29.
Typ publikacji :
Journal Article
MeSH Terms :
Artemisinins*/pharmacology
Artemisinins*/therapeutic use
Brain Edema*/drug therapy
Brain Injuries*
Neural Cell Adhesion Molecule L1*
Neuroprotective Agents*/pharmacology
Animals ; Cerebral Hemorrhage/complications ; Cerebral Hemorrhage/drug therapy ; Cerebral Hemorrhage/metabolism ; Disease Models, Animal ; Humans ; Mice
Czasopismo naukowe
Tytuł :
A guide for single-particle chromatin tracking in live cell nuclei.
Autorzy :
Zhang M; Department of Physics, Indiana University-Purdue University Indianapolis, Indianapolis, Indiana, USA.
Seitz C; Department of Physics, Indiana University-Purdue University Indianapolis, Indianapolis, Indiana, USA.
Chang G; Department of Physics, Indiana University-Purdue University Indianapolis, Indianapolis, Indiana, USA.
Iqbal F; Department of Physics, Indiana University-Purdue University Indianapolis, Indianapolis, Indiana, USA.
Lin H; Department of Physics, Indiana University-Purdue University Indianapolis, Indianapolis, Indiana, USA.
Liu J; Department of Physics, Indiana University-Purdue University Indianapolis, Indianapolis, Indiana, USA.; Indiana University Melvin and Bren Simon Comprehensive Cancer Center, School of Medicine, Indiana University, Indianapolis, Indiana, USA.; Center for Computational Biology and Bioinformatics, School of Medicine, Indiana University, Indianapolis, Indiana, USA.
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Źródło :
Cell biology international [Cell Biol Int] 2022 May; Vol. 46 (5), pp. 683-700. Date of Electronic Publication: 2022 Jan 30.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Chromatin*
Single Molecule Imaging*
Algorithms
Czasopismo naukowe
Tytuł :
Molecular subgrouping of ependymoma across three anatomic sites and their prognostic implications.
Autorzy :
Chinnam D; Department of Pathology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Gupta K; Department of Histopathology, Post Graduate Institute of Medical Education and Research, Chandigarh, India. .
Kiran T; Department of Community Medicine and School of Public Health, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Saraswati A; Department of Histopathology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Salunke P; Department of Neurosurgery, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Madan R; Department of Radiotherapy, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Kumar N; Department of Radiotherapy, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Radotra BD; Department of Histopathology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
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Źródło :
Brain tumor pathology [Brain Tumor Pathol] 2022 Jul; Vol. 39 (3), pp. 151-161. Date of Electronic Publication: 2022 Mar 29.
Typ publikacji :
Journal Article
MeSH Terms :
Ependymoma*/diagnosis
Ependymoma*/genetics
Ependymoma*/pathology
Neural Cell Adhesion Molecule L1*/metabolism
Supratentorial Neoplasms*/pathology
Child, Preschool ; Histones/genetics ; Humans ; Prognosis ; Retrospective Studies ; Transcription Factor RelA/metabolism
SCR Disease Name :
Familial ependymoma
Czasopismo naukowe
Tytuł :
The Structural Dynamics of Translation.
Autorzy :
Korostelev AA; RNA Therapeutics Institute, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA; email: .
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Źródło :
Annual review of biochemistry [Annu Rev Biochem] 2022 Jun 21; Vol. 91, pp. 245-267. Date of Electronic Publication: 2022 Mar 14.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Ribosomes*/metabolism
Single Molecule Imaging*
Cryoelectron Microscopy
Czasopismo naukowe
Tytuł :
R-BIND 2.0: An Updated Database of Bioactive RNA-Targeting Small Molecules and Associated RNA Secondary Structures.
Autorzy :
Donlic A; Department of Chemical and Biological Engineering, Princeton University, Princeton, New Jersey 08540, United States.
Swanson EG; Department of Chemistry, Duke University, 124 Science Drive, Durham, North Carolina 27705, United States.
Chiu LY; Department of Chemistry, Case Western Reserve University, Cleveland, Ohio 441106, United States.
Wicks SL; Department of Chemistry, Duke University, 124 Science Drive, Durham, North Carolina 27705, United States.
Juru AU; Department of Chemistry, Duke University, 124 Science Drive, Durham, North Carolina 27705, United States.
Cai Z; Department of Chemistry, Duke University, 124 Science Drive, Durham, North Carolina 27705, United States.
Kassam K; Department of Chemistry, Duke University, 124 Science Drive, Durham, North Carolina 27705, United States.
Laudeman C; Department of Chemistry, Duke University, 124 Science Drive, Durham, North Carolina 27705, United States.
Sanaba BG; Department of Chemistry, Duke University, 124 Science Drive, Durham, North Carolina 27705, United States.
Sugarman A; Department of Chemistry, Case Western Reserve University, Cleveland, Ohio 441106, United States.
Han E; Department of Chemistry, Duke University, 124 Science Drive, Durham, North Carolina 27705, United States.
Tolbert BS; Department of Chemistry, Case Western Reserve University, Cleveland, Ohio 441106, United States.
Hargrove AE; Department of Chemistry, Duke University, 124 Science Drive, Durham, North Carolina 27705, United States.
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Źródło :
ACS chemical biology [ACS Chem Biol] 2022 Jun 17; Vol. 17 (6), pp. 1556-1566. Date of Electronic Publication: 2022 May 20.
Typ publikacji :
Journal Article
MeSH Terms :
RNA*/metabolism
Small Molecule Libraries*/chemistry
Databases, Nucleic Acid ; Ligands ; RNA Probes
Czasopismo naukowe
Tytuł :
Characterizing dark state kinetics and single molecule fluorescence of FusionRed and FusionRed-MQ at low irradiances.
Autorzy :
Mukherjee S; JILA, University of Colorado, Boulder and National Institute of Standards and Technology, 440 UCB, Boulder, Colorado 80309, USA. .; Department of Chemistry, University of Colorado, Boulder, 215 UCB, Boulder, Colorado 80309, USA.
Thomas C; JILA, University of Colorado, Boulder and National Institute of Standards and Technology, 440 UCB, Boulder, Colorado 80309, USA. .
Wilson R; JILA, University of Colorado, Boulder and National Institute of Standards and Technology, 440 UCB, Boulder, Colorado 80309, USA. .; Department of Physics, University of Colorado, Boulder, 390 UCB, Boulder, Colorado, 80309, USA.
Simmerman E; Department of Applied Physics, Stanford University, 348 Via Pueblo Mall, Stanford, CA 94305-4090, USA.
Hung ST; Department of Physics, National Sun Yat-sen University, Kaohsiung 80424, Taiwan. .
Jimenez R; JILA, University of Colorado, Boulder and National Institute of Standards and Technology, 440 UCB, Boulder, Colorado 80309, USA. .; Department of Chemistry, University of Colorado, Boulder, 215 UCB, Boulder, Colorado 80309, USA.
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Źródło :
Physical chemistry chemical physics : PCCP [Phys Chem Chem Phys] 2022 Jun 15; Vol. 24 (23), pp. 14310-14323. Date of Electronic Publication: 2022 Jun 15.
Typ publikacji :
Journal Article
MeSH Terms :
Single Molecule Imaging*/methods
Kinetics ; Microscopy, Fluorescence/methods ; Photobleaching
Czasopismo naukowe

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