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Tytuł:
IL-13 as Target to Reduce Cholestasis and Dysbiosis in Abcb4 Knockout Mice.
Autorzy:
Hahn L; Department of Gastroenterology, Justus-Liebig-University, D-35392 Giessen, Germany.
Helmrich N; Department of Gastroenterology, Justus-Liebig-University, D-35392 Giessen, Germany.
Herebian D; Department of General Pediatrics, Neonatology and Pediatric Cardiology, Medical Faculty, Heinrich-Heine-University, D-40225 Duesseldorf, Germany.
Mayatepek E; Department of General Pediatrics, Neonatology and Pediatric Cardiology, Medical Faculty, Heinrich-Heine-University, D-40225 Duesseldorf, Germany.
Drebber U; Institute for Pathology, University Hospital of Cologne, D-50937 Cologne, Germany.
Domann E; Institute of Medical Microbiology, German Centre for Infection Research (DZIF Partner Site Giessen-Marburg-Langen), Justus-Liebig-University, D-35392 Giessen, Germany.
Olejniczak S; Institute of Medical Microbiology, German Centre for Infection Research (DZIF Partner Site Giessen-Marburg-Langen), Justus-Liebig-University, D-35392 Giessen, Germany.
Weigel M; Institute of Medical Microbiology, German Centre for Infection Research (DZIF Partner Site Giessen-Marburg-Langen), Justus-Liebig-University, D-35392 Giessen, Germany.
Hain T; Institute of Medical Microbiology, German Centre for Infection Research (DZIF Partner Site Giessen-Marburg-Langen), Justus-Liebig-University, D-35392 Giessen, Germany.
Rath T; Department of Medicine 1, Division of Gastroenterology, Pneumology and Endocrinology, Friedrich-Alexander University Erlangen-Nuremberg, D-91054 Erlangen, Germany.
Wirtz S; Department of Medicine 1, Division of Gastroenterology, Pneumology and Endocrinology, Friedrich-Alexander University Erlangen-Nuremberg, D-91054 Erlangen, Germany.
Mollenkopf HJ; Core Facility Microarray, Max Planck Institute for Infection Biology, D-10117 Berlin, Germany.
Schmidt N; Institute of Hygiene and Infectious Diseases of Animals, Justus-Liebig-University Giessen, D-35392 Giessen, Germany.
Ewers C; Institute of Hygiene and Infectious Diseases of Animals, Justus-Liebig-University Giessen, D-35392 Giessen, Germany.
Baier A; Department of Gastroenterology, Justus-Liebig-University, D-35392 Giessen, Germany.
Churin Y; Department of Gastroenterology, Justus-Liebig-University, D-35392 Giessen, Germany.
Windhorst A; Institute for Medical Informatics, Justus-Liebig-University, D-35392 Giessen, Germany.
Weiskirchen R; Institute of Molecular Pathobiochemistry, Experimental Gene Therapy and Clinical Chemistry (IFMPEGKC), University Hospital, RWTH Aachen University, D-52074 Aachen, Germany.
Steinhoff U; Institute for Medical Microbiology and Hospital Hygiene, Philipps University Marburg, D-35043 Marburg, Germany.
Roeb E; Department of Gastroenterology, Justus-Liebig-University, D-35392 Giessen, Germany.
Roderfeld M; Department of Gastroenterology, Justus-Liebig-University, D-35392 Giessen, Germany.
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Źródło:
Cells [Cells] 2020 Aug 24; Vol. 9 (9). Date of Electronic Publication: 2020 Aug 24.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cholestasis, Intrahepatic/*therapy
Dysbiosis/*therapy
Interleukin-13/*metabolism
Animals ; Disease Models, Animal ; Humans ; Mice ; Mice, Knockout
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Author Correction: The Henna pigment Lawsone activates the Aryl Hydrocarbon Receptor and impacts skin homeostasis.
Autorzy:
Lozza L; Department of Immunology, Max Planck Institute for Infection Biology, Charitéplatz 1, D-10117, Berlin, Germany. .
Moura-Alves P; Department of Immunology, Max Planck Institute for Infection Biology, Charitéplatz 1, D-10117, Berlin, Germany. .; Nuffield Department of Clinical Medicine, Ludwig Institute for Cancer Research, University of Oxford, Oxford, UK. .
Domaszewska T; Department of Immunology, Max Planck Institute for Infection Biology, Charitéplatz 1, D-10117, Berlin, Germany.
Crespo CL; CEDOC, NOVA Medical School, NOVA University of Lisbon, Lisbon, 1169-056, Portugal.
Streata I; Human Genomics Laboratory - University of Medicine and Pharmacy of Craiova, Craiova, Romania.
Kreuchwig A; Leibniz-Forschungsinstitut fuer Molekulare Pharmakologie (FMP), Robert-Rössle-Strasse 10, 13125, Berlin, Germany.
Puyskens A; Department of Immunology, Max Planck Institute for Infection Biology, Charitéplatz 1, D-10117, Berlin, Germany.
Bechtle M; Department of Immunology, Max Planck Institute for Infection Biology, Charitéplatz 1, D-10117, Berlin, Germany.
Klemm M; Department of Immunology, Max Planck Institute for Infection Biology, Charitéplatz 1, D-10117, Berlin, Germany.
Zedler U; Department of Immunology, Max Planck Institute for Infection Biology, Charitéplatz 1, D-10117, Berlin, Germany.
Ungureanu BS; Research Center of Gastroenterology and Hepatology, University of Medicine and Pharmacy of Craiova, Craiova, Romania.
Guhlich-Bornhof U; Department of Immunology, Max Planck Institute for Infection Biology, Charitéplatz 1, D-10117, Berlin, Germany.
Koehler AB; Department of Immunology, Max Planck Institute for Infection Biology, Charitéplatz 1, D-10117, Berlin, Germany.
Stäber M; Department of Immunology, Max Planck Institute for Infection Biology, Charitéplatz 1, D-10117, Berlin, Germany.
Mollenkopf HJ; Microarray Core Facility, Max Planck Institute for Infection Biology, Charitéplatz 1, D-10117,, Berlin, Germany.
Hurwitz R; Biochemistry and Protein Purification Core Facility, Max Planck Institute for Infection Biology. Charitéplatz 1, D-10117, Berlin, Germany.
Furkert J; Leibniz-Forschungsinstitut fuer Molekulare Pharmakologie (FMP), Robert-Rössle-Strasse 10, 13125, Berlin, Germany.
Krause G; Leibniz-Forschungsinstitut fuer Molekulare Pharmakologie (FMP), Robert-Rössle-Strasse 10, 13125, Berlin, Germany.
Weiner J 3rd; Department of Immunology, Max Planck Institute for Infection Biology, Charitéplatz 1, D-10117, Berlin, Germany.
Jacinto A; CEDOC, NOVA Medical School, NOVA University of Lisbon, Lisbon, 1169-056, Portugal.
Mihai I; Human Genomics Laboratory - University of Medicine and Pharmacy of Craiova, Craiova, Romania.
Leite-de-Moraes M; Laboratory of Immunoregulation and Immunopathology, INEM (Institut Necker-Enfants Malades), CNRS UMR8253, INSERM UMR1151 and Paris Descartes University, Paris, France.
Siebenhaar F; Department of Dermatology and Allergy, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Maurer M; Department of Dermatology and Allergy, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Kaufmann SHE; Department of Immunology, Max Planck Institute for Infection Biology, Charitéplatz 1, D-10117, Berlin, Germany. .; Hagler Institute for Advanced Study, Texas A&M University, College Station, TX, USA. .
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Źródło:
Scientific reports [Sci Rep] 2020 May 20; Vol. 10 (1), pp. 8640. Date of Electronic Publication: 2020 May 20.
Typ publikacji:
Published Erratum
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The Henna pigment Lawsone activates the Aryl Hydrocarbon Receptor and impacts skin homeostasis.
Autorzy:
Lozza L; Department of Immunology, Max Planck Institute for Infection Biology, Charitéplatz 1, D-10117, Berlin, Germany. .
Moura-Alves P; Department of Immunology, Max Planck Institute for Infection Biology, Charitéplatz 1, D-10117, Berlin, Germany. .; Nuffield Department of Clinical Medicine, Ludwig Institute for Cancer Research, University of Oxford, Oxford, UK. .
Domaszewska T; Department of Immunology, Max Planck Institute for Infection Biology, Charitéplatz 1, D-10117, Berlin, Germany.
Lage Crespo C; CEDOC, NOVA Medical School, NOVA University of Lisbon, Lisbon, 1169-056, Portugal.
Streata I; Human Genomics Laboratory - University of Medicine and Pharmacy of Craiova, Craiova, Romania.
Kreuchwig A; Leibniz-Forschungsinstitut fuer Molekulare Pharmakologie (FMP), Robert-Rössle-Strasse 10, 13125, Berlin, Germany.
Puyskens A; Department of Immunology, Max Planck Institute for Infection Biology, Charitéplatz 1, D-10117, Berlin, Germany.
Bechtle M; Department of Immunology, Max Planck Institute for Infection Biology, Charitéplatz 1, D-10117, Berlin, Germany.
Klemm M; Department of Immunology, Max Planck Institute for Infection Biology, Charitéplatz 1, D-10117, Berlin, Germany.
Zedler U; Department of Immunology, Max Planck Institute for Infection Biology, Charitéplatz 1, D-10117, Berlin, Germany.
Silviu Ungureanu B; Research Center of Gastroenterology and Hepatology, University of Medicine and Pharmacy of Craiova, Craiova, Romania.
Guhlich-Bornhof U; Department of Immunology, Max Planck Institute for Infection Biology, Charitéplatz 1, D-10117, Berlin, Germany.
Koehler AB; Department of Immunology, Max Planck Institute for Infection Biology, Charitéplatz 1, D-10117, Berlin, Germany.
Stäber M; Department of Immunology, Max Planck Institute for Infection Biology, Charitéplatz 1, D-10117, Berlin, Germany.
Mollenkopf HJ; Microarray Core Facility, Max Planck Institute for Infection Biology, Charitéplatz 1, D-10117, Berlin, Germany.
Hurwitz R; Biochemistry and Protein Purification Core Facility, Max Planck Institute for Infection Biology. Charitéplatz 1, D-10117, Berlin, Germany.
Furkert J; Leibniz-Forschungsinstitut fuer Molekulare Pharmakologie (FMP), Robert-Rössle-Strasse 10, 13125, Berlin, Germany.
Krause G; Leibniz-Forschungsinstitut fuer Molekulare Pharmakologie (FMP), Robert-Rössle-Strasse 10, 13125, Berlin, Germany.
Weiner J 3rd; Department of Immunology, Max Planck Institute for Infection Biology, Charitéplatz 1, D-10117, Berlin, Germany.
Jacinto A; CEDOC, NOVA Medical School, NOVA University of Lisbon, Lisbon, 1169-056, Portugal.
Mihai I; Human Genomics Laboratory - University of Medicine and Pharmacy of Craiova, Craiova, Romania.
Leite-de-Moraes M; Laboratory of Immunoregulation and Immunopathology, INEM (Institut Necker-Enfants Malades), CNRS UMR8253, INSERM UMR1151 and Paris Descartes University, Paris, France.
Siebenhaar F; Department of Dermatology and Allergy, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Maurer M; Department of Dermatology and Allergy, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Kaufmann SHE; Department of Immunology, Max Planck Institute for Infection Biology, Charitéplatz 1, D-10117, Berlin, Germany. .; Hagler Institute for Advanced Study, Texas A&M University, College Station, TX, USA. .
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Źródło:
Scientific reports [Sci Rep] 2019 Jul 26; Vol. 9 (1), pp. 10878. Date of Electronic Publication: 2019 Jul 26.
Typ publikacji:
Journal Article
MeSH Terms:
Dermatitis/*drug therapy
Keratinocytes/*metabolism
Naphthoquinones/*metabolism
Receptors, Aryl Hydrocarbon/*metabolism
Skin/*metabolism
Animals ; Cells, Cultured ; Guided Tissue Regeneration ; Homeostasis ; Humans ; Lawsonia Plant ; Mice ; Models, Animal ; Naphthoquinones/therapeutic use ; Skin/drug effects ; Skin/pathology ; Wound Healing ; Zebrafish
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Mycobacterium tuberculosis infection modulates adipose tissue biology.
Autorzy:
Beigier-Bompadre M; Department of Immunology, Max Planck Institute for Infection Biology, Berlin, Germany.
Montagna GN; Parasitology Unit, Max Planck Institute for Infection Biology, Berlin, Germany.
Kühl AA; Medical Department, Division of Gastroenterology, Infectiology and Rheumatology, Charité - University Medicine, Berlin, Germany.
Lozza L; Department of Immunology, Max Planck Institute for Infection Biology, Berlin, Germany.
Weiner J 3rd; Department of Immunology, Max Planck Institute for Infection Biology, Berlin, Germany.
Kupz A; Department of Immunology, Max Planck Institute for Infection Biology, Berlin, Germany.
Vogelzang A; Department of Immunology, Max Planck Institute for Infection Biology, Berlin, Germany.
Mollenkopf HJ; Core Facility, Max Planck Institute for Infection Biology, Berlin, Germany.
Löwe D; Department of Immunology, Max Planck Institute for Infection Biology, Berlin, Germany.
Bandermann S; Department of Immunology, Max Planck Institute for Infection Biology, Berlin, Germany.
Dorhoi A; Department of Immunology, Max Planck Institute for Infection Biology, Berlin, Germany.
Brinkmann V; Core Facility, Max Planck Institute for Infection Biology, Berlin, Germany.
Matuschewski K; Parasitology Unit, Max Planck Institute for Infection Biology, Berlin, Germany.
Kaufmann SHE; Department of Immunology, Max Planck Institute for Infection Biology, Berlin, Germany.
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Źródło:
PLoS pathogens [PLoS Pathog] 2017 Oct 17; Vol. 13 (10), pp. e1006676. Date of Electronic Publication: 2017 Oct 17 (Print Publication: 2017).
Typ publikacji:
Journal Article
MeSH Terms:
Adipose Tissue/*immunology
Adipose Tissue/*microbiology
Tuberculosis/*immunology
Tuberculosis/*microbiology
Virus Latency/*immunology
Adipocytes/microbiology ; Animals ; CD8-Positive T-Lymphocytes/immunology ; Humans ; Killer Cells, Natural/immunology ; Mice ; Mycobacterium tuberculosis/immunology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Developmental transcriptome of resting cell formation in Mycobacterium smegmatis.
Autorzy:
Wu ML; Antibacterial Drug Discovery Laboratory, Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Gengenbacher M; Tuberculosis Research Laboratory, Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Chung JC; Department of Medicine, Division of Infectious Diseases, Yong Loo Lin School of Medicine, National University of Singapore, National University Health System, Singapore, Singapore.
Chen SL; Department of Medicine, Division of Infectious Diseases, Yong Loo Lin School of Medicine, National University of Singapore, National University Health System, Singapore, Singapore.; Infectious Diseases Group, Genome Institute of Singapore, Singapore, Singapore.
Mollenkopf HJ; Core Facility Microarray / Genomics, Max Planck Institute for Infection Biology, Berlin, Germany.
Kaufmann SH; Department of Immunology, Max Planck Institute for Infection Biology, Berlin, Germany.
Dick T; Antibacterial Drug Discovery Laboratory, Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. thomas_.
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Źródło:
BMC genomics [BMC Genomics] 2016 Oct 26; Vol. 17 (1), pp. 837. Date of Electronic Publication: 2016 Oct 26.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Gene Expression Regulation, Bacterial*
Transcriptome*
Cell Cycle/*genetics
Mycobacterium smegmatis/*genetics
Cluster Analysis ; Gene Expression Profiling ; Genes, Bacterial ; High-Throughput Nucleotide Sequencing
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
IFNs Modify the Proteome of Legionella-Containing Vacuoles and Restrict Infection Via IRG1-Derived Itaconic Acid.
Autorzy:
Naujoks J; Department of Internal Medicine/Infectious Diseases and Pulmonary Medicine, Charité University Medicine Berlin, Berlin, Germany.
Tabeling C; Department of Internal Medicine/Infectious Diseases and Pulmonary Medicine, Charité University Medicine Berlin, Berlin, Germany.
Dill BD; MRC Protein Phosphorylation Unit, University of Dundee, Dundee, United Kingdom.
Hoffmann C; Max-von-Pettenkofer Institute, Ludwig Maximilian University, Munich, Germany.
Brown AS; The Department of Biochemistry and Molecular Biology, The University of Melbourne, Melbourne, Australia.
Kunze M; Department of Internal Medicine/Infectious Diseases and Pulmonary Medicine, Charité University Medicine Berlin, Berlin, Germany.
Kempa S; Integrative Metabolomics and Proteomics, Institute of Medical Systems Biology/Max-Delbrueck Center for Molecular Medicine, Berlin, Germany.
Peter A; Department of Internal Medicine/Infectious Diseases and Pulmonary Medicine, Charité University Medicine Berlin, Berlin, Germany.
Mollenkopf HJ; Max Planck Institute for Infection Biology, Berlin, Germany.
Dorhoi A; Max Planck Institute for Infection Biology, Berlin, Germany.
Kershaw O; Department of Veterinary Pathology, Free University Berlin, Berlin, Germany.
Gruber AD; Department of Veterinary Pathology, Free University Berlin, Berlin, Germany.
Sander LE; Department of Internal Medicine/Infectious Diseases and Pulmonary Medicine, Charité University Medicine Berlin, Berlin, Germany.
Witzenrath M; Department of Internal Medicine/Infectious Diseases and Pulmonary Medicine, Charité University Medicine Berlin, Berlin, Germany.
Herold S; Medizinische Klinik II, University Giessen and Marburg Lung Center, Justus-Liebig-University Giessen, Giessen, Germany.
Nerlich A; Department of Internal Medicine/Infectious Diseases and Pulmonary Medicine, Charité University Medicine Berlin, Berlin, Germany.
Hocke AC; Department of Internal Medicine/Infectious Diseases and Pulmonary Medicine, Charité University Medicine Berlin, Berlin, Germany.
van Driel I; The Department of Biochemistry and Molecular Biology, The University of Melbourne, Melbourne, Australia.
Suttorp N; Department of Internal Medicine/Infectious Diseases and Pulmonary Medicine, Charité University Medicine Berlin, Berlin, Germany.
Bedoui S; The Department of Microbiology and Immunology, The University of Melbourne, Melbourne, Australia.
Hilbi H; Max-von-Pettenkofer Institute, Ludwig Maximilian University, Munich, Germany.; Institute of Medical Microbiology, University of Zurich, Zurich, Switzerland.
Trost M; MRC Protein Phosphorylation Unit, University of Dundee, Dundee, United Kingdom.
Opitz B; Department of Internal Medicine/Infectious Diseases and Pulmonary Medicine, Charité University Medicine Berlin, Berlin, Germany.
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Źródło:
PLoS pathogens [PLoS Pathog] 2016 Feb 01; Vol. 12 (2), pp. e1005408. Date of Electronic Publication: 2016 Feb 01 (Print Publication: 2016).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Proteome*
Hydro-Lyases/*immunology
Interferons/*immunology
Legionella pneumophila/*immunology
Legionnaires' Disease/*immunology
Macrophages, Alveolar/*immunology
Animals ; Disease Models, Animal ; Female ; Gene Expression Regulation ; Gene Ontology ; Hydro-Lyases/genetics ; Hydro-Lyases/metabolism ; Immunity, Innate ; Interferons/metabolism ; Legionella pneumophila/genetics ; Legionella pneumophila/metabolism ; Legionnaires' Disease/metabolism ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Mitochondria/metabolism ; Models, Immunological ; Reactive Oxygen Species/metabolism ; Succinates/metabolism ; Vacuoles/metabolism ; Vacuoles/microbiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Macrophages recognize the Helicobacter pylori type IV secretion system in the absence of toll-like receptor signalling.
Autorzy:
Koch M; Department of Molecular Biology, Max Planck Institute for Infection Biology, Charitéplatz 1, 10117, Berlin, Germany.
Mollenkopf HJ; Department of Molecular Biology, Max Planck Institute for Infection Biology, Charitéplatz 1, 10117, Berlin, Germany.
Meyer TF; Department of Molecular Biology, Max Planck Institute for Infection Biology, Charitéplatz 1, 10117, Berlin, Germany.
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Źródło:
Cellular microbiology [Cell Microbiol] 2016 Jan; Vol. 18 (1), pp. 137-47. Date of Electronic Publication: 2015 Sep 03.
Typ publikacji:
Journal Article
MeSH Terms:
Host-Pathogen Interactions*
Helicobacter pylori/*immunology
Macrophages/*immunology
Macrophages/*microbiology
Toll-Like Receptors/*metabolism
Type IV Secretion Systems/*immunology
Animals ; Gene Expression Profiling ; Immunity, Innate ; Mice
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Correction: pathological impact of hepatitis B virus surface proteins on the liver is associated with the host genetic background.
Autorzy:
Churin Y
Roderfeld M
Stiefel J
Würger T
Schröder D
Matono T
Mollenkopf HJ
Montalbano R
Pompaiah M
Reifenberg K
Zahner D
Ocker M
Gerlich W
Glebe D
Roeb E
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Źródło:
PloS one [PLoS One] 2015 May 01; Vol. 10 (5), pp. e0127375. Date of Electronic Publication: 2015 May 01 (Print Publication: 2015).
Typ publikacji:
Published Erratum
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Comprehensive insights into transcriptional adaptation of intracellular mycobacteria by microbe-enriched dual RNA sequencing.
Autorzy:
Rienksma RA; Laboratory of Systems and Synthetic Biology, Wageningen University and Research Centre, Dreijenplein 10, 6703, HB, Wageningen, the Netherlands. .
Suarez-Diez M; Laboratory of Systems and Synthetic Biology, Wageningen University and Research Centre, Dreijenplein 10, 6703, HB, Wageningen, the Netherlands. .
Mollenkopf HJ; Core Facility Microarray/Genomics, Max Planck Institute for Infection Biology, Charitéplatz 1, 10117, Berlin, Germany. mollenkopf@mpiib-berlin.mpg.de.
Dolganov GM; Department of Microbiology and Immunology, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA, 94305-5124, USA. .
Dorhoi A; Department of Immunology, Max Planck Institute for Infection Biology, Charitéplatz 1, 10117, Berlin, Germany. .
Schoolnik GK; Department of Microbiology and Immunology, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA, 94305-5124, USA. .
Martins Dos Santos VA; Laboratory of Systems and Synthetic Biology, Wageningen University and Research Centre, Dreijenplein 10, 6703, HB, Wageningen, the Netherlands. .; LifeGlimmer GmbH, Markelstrasse 38, 12163, Berlin, Germany. .
Kaufmann SH; Department of Immunology, Max Planck Institute for Infection Biology, Charitéplatz 1, 10117, Berlin, Germany. .
Schaap PJ; Laboratory of Systems and Synthetic Biology, Wageningen University and Research Centre, Dreijenplein 10, 6703, HB, Wageningen, the Netherlands. .
Gengenbacher M; Department of Immunology, Max Planck Institute for Infection Biology, Charitéplatz 1, 10117, Berlin, Germany. .; Present address: Department of Microbiology, Yong Loo Lin School of Medicine, National University of Singapore, 5 Science Drive 2, Singapore, 117545, Singapore. .
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Źródło:
BMC genomics [BMC Genomics] 2015 Feb 05; Vol. 16, pp. 34. Date of Electronic Publication: 2015 Feb 05.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Cholesterol/*biosynthesis
Host-Pathogen Interactions/*genetics
Mycobacterium tuberculosis/*genetics
Tuberculosis/*genetics
Animals ; Cattle ; Cholesterol/genetics ; Dendritic Cells/metabolism ; Dendritic Cells/microbiology ; Gene Expression Regulation, Bacterial/drug effects ; High-Throughput Nucleotide Sequencing ; Humans ; Macrophages/microbiology ; Mycobacterium bovis/pathogenicity ; Mycobacterium tuberculosis/pathogenicity ; Phagocytes/metabolism ; Phagocytes/microbiology ; Transcriptome/drug effects ; Tuberculosis/microbiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
AhR sensing of bacterial pigments regulates antibacterial defence.
Autorzy:
Moura-Alves P; 1] Max Planck Institute for Infection Biology, Department of Immunology, Charitéplatz 1, 10117 Berlin, Germany [2].
Faé K; 1] Max Planck Institute for Infection Biology, Department of Immunology, Charitéplatz 1, 10117 Berlin, Germany [2].
Houthuys E; 1] Max Planck Institute for Infection Biology, Department of Immunology, Charitéplatz 1, 10117 Berlin, Germany [2].
Dorhoi A; 1] Max Planck Institute for Infection Biology, Department of Immunology, Charitéplatz 1, 10117 Berlin, Germany [2].
Kreuchwig A; Leibniz Institute for Molecular Pharmacology (FMP), Robert-Rössle-Strasse 10, 13125 Berlin, Germany.
Furkert J; Leibniz Institute for Molecular Pharmacology (FMP), Robert-Rössle-Strasse 10, 13125 Berlin, Germany.
Barison N; Max Planck Institute for Infection Biology, Structural Systems Biology, Charitéplatz 1, 10117 Berlin, Germany.
Diehl A; Leibniz Institute for Molecular Pharmacology (FMP), Robert-Rössle-Strasse 10, 13125 Berlin, Germany.
Munder A; Clinical Research Group, Clinic for Pediatric Pneumology, Allergology and Neonatology, OE 6710, Hannover Medical School, Carl-Neuberg-Str. 1, 30625 Hannover, Germany.
Constant P; Institute of Pharmacology and Structural Biology (IPBS), CNRS and University of Toulouse (Toulouse III), 205 Route de Narbonne, 31077, Toulouse cedex 04, Toulouse, France.
Skrahina T; Max Planck Institute for Infection Biology, Department of Immunology, Charitéplatz 1, 10117 Berlin, Germany.
Guhlich-Bornhof U; Max Planck Institute for Infection Biology, Department of Immunology, Charitéplatz 1, 10117 Berlin, Germany.
Klemm M; Max Planck Institute for Infection Biology, Department of Immunology, Charitéplatz 1, 10117 Berlin, Germany.
Koehler AB; Max Planck Institute for Infection Biology, Department of Immunology, Charitéplatz 1, 10117 Berlin, Germany.
Bandermann S; Max Planck Institute for Infection Biology, Department of Immunology, Charitéplatz 1, 10117 Berlin, Germany.
Goosmann C; Microscopy Core Facility, Max Planck Institute for Infection Biology, Department of Immunology, Charitéplatz 1, 10117 Berlin, Germany.
Mollenkopf HJ; Microarray Core Facility, Max Planck Institute for Infection Biology, Department of Immunology, Charitéplatz 1, 10117 Berlin, Germany.
Hurwitz R; Protein Purification Core Facility, Max Planck Institute for Infection Biology, Charitéplatz 1, 10117 Berlin, Germany.
Brinkmann V; Microscopy Core Facility, Max Planck Institute for Infection Biology, Department of Immunology, Charitéplatz 1, 10117 Berlin, Germany.
Fillatreau S; German Rheumatism Research Centre Berlin (DRFZ), a Leibniz Institute, Charitéplatz 1, 10117 Berlin, Germany.
Daffe M; Institute of Pharmacology and Structural Biology (IPBS), CNRS and University of Toulouse (Toulouse III), 205 Route de Narbonne, 31077, Toulouse cedex 04, Toulouse, France.
Tümmler B; Clinical Research Group, Clinic for Pediatric Pneumology, Allergology and Neonatology, OE 6710, Hannover Medical School, Carl-Neuberg-Str. 1, 30625 Hannover, Germany.
Kolbe M; Max Planck Institute for Infection Biology, Structural Systems Biology, Charitéplatz 1, 10117 Berlin, Germany.
Oschkinat H; Leibniz Institute for Molecular Pharmacology (FMP), Robert-Rössle-Strasse 10, 13125 Berlin, Germany.
Krause G; Leibniz Institute for Molecular Pharmacology (FMP), Robert-Rössle-Strasse 10, 13125 Berlin, Germany.
Kaufmann SH; Max Planck Institute for Infection Biology, Department of Immunology, Charitéplatz 1, 10117 Berlin, Germany.
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Źródło:
Nature [Nature] 2014 Aug 28; Vol. 512 (7515), pp. 387-92. Date of Electronic Publication: 2014 Aug 13.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Basic Helix-Loop-Helix Transcription Factors/*metabolism
Mycobacterium tuberculosis/*immunology
Pigments, Biological/*metabolism
Pseudomonas aeruginosa/*immunology
Receptors, Aryl Hydrocarbon/*metabolism
Receptors, Pattern Recognition/*metabolism
Animals ; Anti-Bacterial Agents/metabolism ; Bone Marrow Cells/cytology ; Cytokines/immunology ; Cytokines/metabolism ; Feedback, Physiological ; Humans ; Ligands ; Macrophage Activation ; Mice ; Mycobacterium tuberculosis/growth & development ; Mycobacterium tuberculosis/metabolism ; Phenazines/metabolism ; Pigments, Biological/chemistry ; Pseudomonas Infections/metabolism ; Pseudomonas aeruginosa/metabolism ; Pyocyanine/metabolism ; Virulence Factors/chemistry ; Virulence Factors/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Pathological impact of hepatitis B virus surface proteins on the liver is associated with the host genetic background.
Autorzy:
Churin Y; Department of Gastroenterology, Justus Liebig University, Giessen, Germany.
Roderfeld M; Department of Gastroenterology, Justus Liebig University, Giessen, Germany.
Stiefel J; Department of Gastroenterology, Justus Liebig University, Giessen, Germany.
Würger T; Department of Gastroenterology, Justus Liebig University, Giessen, Germany.
Schröder D; Department of Gastroenterology, Justus Liebig University, Giessen, Germany.
Matono T; Department of Gastroenterology, Justus Liebig University, Giessen, Germany.
Mollenkopf HJ; Core Facility Microarray, Max Planck Institute for Infection Biology, Berlin, Germany.
Montalbano R; Institute for Surgical Research, Philipps University of Marburg, Marburg, Germany.
Pompaiah M; Department of Molecular Biology, Max Planck Institute for Infection Biology, Berlin, Germany.
Reifenberg K; Central Laboratory Animal Facility, Johannes Gutenberg University, Mainz, Germany.
Zahner D; Division of Animal Welfare and Ethology, Justus Liebig University, Giessen, Germany.
Ocker M; Institute for Surgical Research, Philipps University of Marburg, Marburg, Germany.
Gerlich W; Institute of Medical Virology, National Reference Centre for Hepatitis B and D Viruses, Justus Liebig University, Giessen, Germany.
Glebe D; Institute of Medical Virology, National Reference Centre for Hepatitis B and D Viruses, Justus Liebig University, Giessen, Germany.
Roeb E; Department of Gastroenterology, Justus Liebig University, Giessen, Germany.
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Źródło:
PloS one [PLoS One] 2014 Mar 04; Vol. 9 (3), pp. e90608. Date of Electronic Publication: 2014 Mar 04 (Print Publication: 2014).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Host-Pathogen Interactions*
Hepatitis B/*complications
Hepatitis B/*genetics
Hepatitis B virus/*physiology
Liver/*pathology
Liver/*virology
Viral Structural Proteins/*genetics
Animals ; Female ; Gene Expression Regulation ; Hepatitis B/metabolism ; Hepatitis B/pathology ; Liver/metabolism ; Liver Cirrhosis/etiology ; Liver Cirrhosis/genetics ; Liver Neoplasms/etiology ; Liver Neoplasms/genetics ; Male ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Mice, Transgenic ; Phosphorylation ; Signal Transduction ; eIF-2 Kinase/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
The Mycobacterium tuberculosis regulatory network and hypoxia.
Autorzy:
Galagan JE; Department of Biomedical Engineering, Boston University, Boston, Massachusetts 02215, USA. />Minch K
Peterson M
Lyubetskaya A
Azizi E
Sweet L
Gomes A
Rustad T
Dolganov G
Glotova I
Abeel T
Mahwinney C
Kennedy AD
Allard R
Brabant W
Krueger A
Jaini S
Honda B
Yu WH
Hickey MJ
Zucker J
Garay C
Weiner B
Sisk P
Stolte C
Winkler JK
Van de Peer Y
Iazzetti P
Camacho D
Dreyfuss J
Liu Y
Dorhoi A
Mollenkopf HJ
Drogaris P
Lamontagne J
Zhou Y
Piquenot J
Park ST
Raman S
Kaufmann SH
Mohney RP
Chelsky D
Moody DB
Sherman DR
Schoolnik GK
Pokaż więcej
Źródło:
Nature [Nature] 2013 Jul 11; Vol. 499 (7457), pp. 178-83. Date of Electronic Publication: 2013 Jul 03.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Gene Regulatory Networks*/genetics
Hypoxia/*genetics
Metabolic Networks and Pathways/*genetics
Mycobacterium tuberculosis/*genetics
Mycobacterium tuberculosis/*metabolism
Adaptation, Physiological ; Bacterial Proteins/genetics ; Bacterial Proteins/metabolism ; Binding Sites ; Chromatin Immunoprecipitation ; Gene Expression Profiling ; Genomics ; Hypoxia/metabolism ; Lipid Metabolism/genetics ; Models, Biological ; Mycobacterium tuberculosis/drug effects ; Mycobacterium tuberculosis/physiology ; Oxygen/pharmacology ; Proteolysis ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Reproducibility of Results ; Sequence Analysis, DNA ; Transcription Factors/genetics ; Transcription Factors/metabolism ; Tuberculosis/metabolism ; Tuberculosis/microbiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
A new algorithm for integrated analysis of miRNA-mRNA interactions based on individual classification reveals insights into bladder cancer.
Autorzy:
Hecker N; Center for Bioinformatics, University of Hamburg, Hamburg, Germany.
Stephan C
Mollenkopf HJ
Jung K
Preissner R
Meyer HA
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Źródło:
PloS one [PLoS One] 2013 May 24; Vol. 8 (5), pp. e64543. Date of Electronic Publication: 2013 May 24 (Print Publication: 2013).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Algorithms*
Computational Biology/*methods
MicroRNAs/*genetics
RNA, Messenger/*genetics
Urinary Bladder Neoplasms/*genetics
Aged ; Aged, 80 and over ; Cluster Analysis ; Female ; Gene Expression Profiling ; Gene Expression Regulation, Neoplastic ; Gene Regulatory Networks ; Humans ; Male ; MicroRNAs/metabolism ; Middle Aged ; RNA, Messenger/metabolism ; Sensitivity and Specificity ; Signal Transduction ; Urinary Bladder Neoplasms/metabolism ; Urinary Bladder Neoplasms/pathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Direct proteomic quantification of the secretome of activated immune cells.
Autorzy:
Meissner F; Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany.
Scheltema RA
Mollenkopf HJ
Mann M
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Źródło:
Science (New York, N.Y.) [Science] 2013 Apr 26; Vol. 340 (6131), pp. 475-8.
Typ publikacji:
Journal Article
MeSH Terms:
Macrophage Activation*
Macrophages/*immunology
Mass Spectrometry/*methods
Proteins/*metabolism
Proteome/*metabolism
Toll-Like Receptor 4/*agonists
Animals ; Lipopolysaccharides/immunology ; Mice ; Mice, Knockout ; Proteins/genetics ; Proteome/genetics ; Proteomics ; Transcription, Genetic ; Transcriptome
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Propionibacterium acnes host cell tropism contributes to vimentin-mediated invasion and induction of inflammation.
Autorzy:
Mak TN; Department of Molecular Biology, Max Planck Institute for Infection Biology, Berlin, Germany.
Fischer N
Laube B
Brinkmann V
Metruccio MM
Sfanos KS
Mollenkopf HJ
Meyer TF
Brüggemann H
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Źródło:
Cellular microbiology [Cell Microbiol] 2012 Nov; Vol. 14 (11), pp. 1720-33. Date of Electronic Publication: 2012 Jul 22.
Typ publikacji:
Journal Article
MeSH Terms:
Endocytosis*
Host-Pathogen Interactions*
Inflammation*
Epithelial Cells/*microbiology
Propionibacterium acnes/*pathogenicity
Vimentin/*metabolism
Acne Vulgaris/microbiology ; Acne Vulgaris/pathology ; Cell Line ; Epithelial Cells/immunology ; Gene Expression Profiling ; Gene Knockdown Techniques ; Humans ; Male ; Prostatitis/microbiology ; Prostatitis/pathology ; Vimentin/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Reference miRNAs for miRNAome analysis of urothelial carcinomas.
Autorzy:
Ratert N; Department of Urology, University Hospital Charité, Berlin, Germany.
Meyer HA
Jung M
Mollenkopf HJ
Wagner I
Miller K
Kilic E
Erbersdobler A
Weikert S
Jung K
Pokaż więcej
Źródło:
PloS one [PLoS One] 2012; Vol. 7 (6), pp. e39309. Date of Electronic Publication: 2012 Jun 20.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
MicroRNAs/*genetics
Urinary Bladder Neoplasms/*genetics
Aged ; Aged, 80 and over ; Female ; Gene Expression Profiling ; Humans ; Male ; Middle Aged ; Real-Time Polymerase Chain Reaction
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
MiR-133b targets antiapoptotic genes and enhances death receptor-induced apoptosis.
Autorzy:
Patron JP; Department of Immunology, Max Planck Institute for Infection Biology, Berlin, Germany.
Fendler A
Bild M
Jung U
Müller H
Arntzen MØ
Piso C
Stephan C
Thiede B
Mollenkopf HJ
Jung K
Kaufmann SH
Schreiber J
Pokaż więcej
Źródło:
PloS one [PLoS One] 2012; Vol. 7 (4), pp. e35345. Date of Electronic Publication: 2012 Apr 20.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis/*genetics
MicroRNAs/*genetics
Receptors, Death Domain/*genetics
TNF-Related Apoptosis-Inducing Ligand/*genetics
Adenocarcinoma/genetics ; Adenocarcinoma/pathology ; Apoptosis/drug effects ; Apoptosis Regulatory Proteins/genetics ; Glutathione Transferase/genetics ; HeLa Cells ; Humans ; Male ; MicroRNAs/metabolism ; Prostatic Neoplasms/genetics ; Prostatic Neoplasms/pathology ; Transfection ; Tumor Cells, Cultured ; Tumor Necrosis Factor-alpha/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Comparative genomics and transcriptomics of Propionibacterium acnes.
Autorzy:
Brzuszkiewicz E; Göttingen Genomics Laboratory, Institute of Microbiology and Genetics, Georg-August-University of Göttingen, Göttingen, Germany.
Weiner J
Wollherr A
Thürmer A
Hüpeden J
Lomholt HB
Kilian M
Gottschalk G
Daniel R
Mollenkopf HJ
Meyer TF
Brüggemann H
Pokaż więcej
Źródło:
PloS one [PLoS One] 2011; Vol. 6 (6), pp. e21581. Date of Electronic Publication: 2011 Jun 27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Bacterial Proteins/*genetics
Genomics/*methods
Propionibacterium acnes/*genetics
Transcriptome/*genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
The microRNA miR-182 is induced by IL-2 and promotes clonal expansion of activated helper T lymphocytes.
Autorzy:
Stittrich AB; Deutsches Rheuma-Forschungszentrum Berlin, Berlin, Germany.
Haftmann C
Sgouroudis E
Kühl AA
Hegazy AN
Panse I
Riedel R
Flossdorf M
Dong J
Fuhrmann F
Heinz GA
Fang Z
Li N
Bissels U
Hatam F
Jahn A
Hammoud B
Matz M
Schulze FM
Baumgrass R
Bosio A
Mollenkopf HJ
Grün J
Thiel A
Chen W
Höfer T
Loddenkemper C
Löhning M
Chang HD
Rajewsky N
Radbruch A
Mashreghi MF
Pokaż więcej
Źródło:
Nature immunology [Nat Immunol] 2010 Nov; Vol. 11 (11), pp. 1057-62. Date of Electronic Publication: 2010 Oct 10.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Interleukin-2/*immunology
MicroRNAs/*immunology
T-Lymphocytes, Helper-Inducer/*cytology
T-Lymphocytes, Helper-Inducer/*immunology
Animals ; Arthritis/immunology ; Cell Proliferation ; Cells, Cultured ; Disease Models, Animal ; Humans ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Restricted expression of C-type lectin-like natural killer receptors by CD8 T cells in the murine small intestine.
Autorzy:
Jänner N; Department of Immunology, Max Planck Institute for Infection Biology, Charitéplatz, Berlin, Germany.
Hahnke K
Mollenkopf HJ
Steinhoff U
Kaufmann SH
Mittrücker HW
Pokaż więcej
Źródło:
Immunology [Immunology] 2008 Sep; Vol. 125 (1), pp. 38-47. Date of Electronic Publication: 2008 Feb 22.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
CD8-Positive T-Lymphocytes/*immunology
Intestine, Small/*immunology
Lectins, C-Type/*metabolism
Listeriosis/*immunology
Receptors, KIR/*metabolism
Animals ; CD8-Positive T-Lymphocytes/drug effects ; Cells, Cultured ; Gene Expression Profiling/methods ; Gene Expression Regulation/drug effects ; Germ-Free Life ; Immunity, Mucosal ; Intestinal Mucosa/immunology ; Intestinal Mucosa/microbiology ; Intestine, Small/microbiology ; Lectins, C-Type/genetics ; Liver/immunology ; Lymphocyte Activation/immunology ; Mice ; Mice, Inbred C57BL ; Ovalbumin/immunology ; Receptors, KIR/genetics ; Spleen/immunology ; Tretinoin/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Wyświetlanie 1-20 z 22

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