Temat: "Monoamine Oxidase" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Potential of Tryptamine Derivatives as Multi-Target Directed Ligands for Alzheimer's Disease: AChE, MAO-B, and COX-2 as Molecular Targets.
Autorzy:: Asghar S; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Hamdard University, Karachi 74600, Pakistan.
Mushtaq N; Department of Pharmaceutical Chemistry, Faculty of Pharmacy and Pharmaceutical Sciences, University of Karachi, Karachi 75270, Pakistan.
Ahmed A; Institute of Pharmaceutical Sciences, Jinnah Sindh Medical University, Karachi 75510, Pakistan.
Anwar L; Department of Pharmacology, Faculty of Pharmacy, Hamdard University, Karachi 74600, Pakistan.
Munawar R; Department of Pharmaceutical Chemistry, Dow College of Pharmacy, Dow University of Health Sciences, Karachi 74200, Pakistan.
Akhtar S; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Hamdard University, Karachi 74600, Pakistan.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2024 Jan 19; Vol. 29 (2). Date of Electronic Publication: 2024 Jan 19.
Typ publikacji:: Journal Article
MeSH Terms:: Monoamine Oxidase*/metabolism
Alzheimer Disease*/metabolism
Humans ; Monoamine Oxidase Inhibitors/chemistry ; Cyclooxygenase 2/metabolism ; Molecular Docking Simulation ; Cholinesterase Inhibitors/pharmacology ; Cholinesterase Inhibitors/therapeutic use ; Cholinesterase Inhibitors/chemistry ; Structure-Activity Relationship ; Tryptamines/pharmacology ; Acetylcholinesterase/metabolism ; Ligands

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Skocz do pozycji: 2.

Tytuł:: Latest advances in dual inhibitors of acetylcholinesterase and monoamine oxidase B against Alzheimer's disease.
Autorzy:: Zou D; College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, China.
Liu R; College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, China.
Lv Y; College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, China.
Guo J; College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, China.
Zhang C; College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, China.
Xie Y; College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, China.; Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceutical, Zhejiang University of Technology, Hangzhou, China.; Key Laboratory for Green Pharmaceutical Technologies and Related Equipment of Ministry of Education, Key Laboratory of Pharmaceutical Engineering of Zhejiang Province, Hangzhou, China.; Pokaż więcej
Źródło:: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2023 Dec; Vol. 38 (1), pp. 2270781. Date of Electronic Publication: 2023 Nov 13.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Monoamine Oxidase*/metabolism
Alzheimer Disease*/drug therapy
Humans ; Acetylcholinesterase/metabolism ; Monoamine Oxidase Inhibitors/pharmacology ; Monoamine Oxidase Inhibitors/chemistry ; Molecular Docking Simulation ; Cholinesterase Inhibitors/pharmacology ; Cholinesterase Inhibitors/chemistry ; Structure-Activity Relationship

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Skocz do pozycji: 3.

Tytuł:: Molecular Investigation of the Antitumor Effects of Monoamine Oxidase Inhibitors in Breast Cancer Cells.
Autorzy:: Alkhawaldeh A; Department of Pharmaceutical Sciences, School of Pharmacy, University of Jordan, Queen Rania Street, Amman 11942, Jordan.
Bardaweel S; Department of Pharmaceutical Sciences, School of Pharmacy, University of Jordan, Queen Rania Street, Amman 11942, Jordan.; Pokaż więcej
Źródło:: BioMed research international [Biomed Res Int] 2023 Oct 05; Vol. 2023, pp. 2592691. Date of Electronic Publication: 2023 Oct 05 (Print Publication: 2023).
Typ publikacji:: Journal Article
MeSH Terms:: Monoamine Oxidase Inhibitors*/pharmacology
Breast Neoplasms*/drug therapy
Breast Neoplasms*/genetics
Male ; Humans ; Monoamine Oxidase/genetics ; Monoamine Oxidase/metabolism ; Oxidative Stress ; Reactive Oxygen Species/metabolism

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Skocz do pozycji: 4.

Tytuł:: Investigation on Novel E/Z 2-Benzylideneindan-1-One-Based Photoswitches with AChE and MAO-B Dual Inhibitory Activity.
Autorzy:: Paolino M; Department of Biotechnology, Chemistry and Pharmacy, University of Siena, Via A. Moro 2, I-53100 Siena, Italy.
de Candia M; Department of Pharmacy-Pharmaceutical Sciences, University of Bari Aldo Moro, Via E. Orabona 4, I-70125 Bari, Italy.
Purgatorio R; Department of Pharmacy-Pharmaceutical Sciences, University of Bari Aldo Moro, Via E. Orabona 4, I-70125 Bari, Italy.
Catto M; Department of Pharmacy-Pharmaceutical Sciences, University of Bari Aldo Moro, Via E. Orabona 4, I-70125 Bari, Italy.
Saletti M; Department of Biotechnology, Chemistry and Pharmacy, University of Siena, Via A. Moro 2, I-53100 Siena, Italy.
Tondo AR; Department of Pharmacy-Pharmaceutical Sciences, University of Bari Aldo Moro, Via E. Orabona 4, I-70125 Bari, Italy.
Nicolotti O; Department of Pharmacy-Pharmaceutical Sciences, University of Bari Aldo Moro, Via E. Orabona 4, I-70125 Bari, Italy.
Cappelli A; Department of Biotechnology, Chemistry and Pharmacy, University of Siena, Via A. Moro 2, I-53100 Siena, Italy.
Brizzi A; Department of Biotechnology, Chemistry and Pharmacy, University of Siena, Via A. Moro 2, I-53100 Siena, Italy.
Mugnaini C; Department of Biotechnology, Chemistry and Pharmacy, University of Siena, Via A. Moro 2, I-53100 Siena, Italy.
Corelli F; Department of Biotechnology, Chemistry and Pharmacy, University of Siena, Via A. Moro 2, I-53100 Siena, Italy.
Altomare CD; Department of Pharmacy-Pharmaceutical Sciences, University of Bari Aldo Moro, Via E. Orabona 4, I-70125 Bari, Italy.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2023 Aug 03; Vol. 28 (15). Date of Electronic Publication: 2023 Aug 03.
Typ publikacji:: Journal Article
MeSH Terms:: Monoamine Oxidase*/metabolism
Alzheimer Disease*/drug therapy
Humans ; Acetylcholinesterase/metabolism ; Monoamine Oxidase Inhibitors/pharmacology ; Monoamine Oxidase Inhibitors/therapeutic use ; Molecular Docking Simulation ; Cholinesterase Inhibitors/pharmacology ; Cholinesterase Inhibitors/therapeutic use ; Structure-Activity Relationship

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Skocz do pozycji: 5.

Tytuł:: Rethinking, reducing, and refining the classical oral tyramine challenge test of monoamine oxidase (MAO) inhibitors.
Autorzy:: van Hoogdalem EJ; Drug Development Solutions - Clinical Pharmacology, ICON, Groningen, The Netherlands.
Smith KL; Biostatistics Consulting, ICON, Reading, UK.
Hartstra J; Drug Development Solutions - Pharmacokinetics, ICON, Groningen, The Netherlands.
Constant J; Scientific Affairs, ICON, Victoria, British Columbia, Canada.; Pokaż więcej
Źródło:: Clinical and translational science [Clin Transl Sci] 2023 Oct; Vol. 16 (10), pp. 2058-2069. Date of Electronic Publication: 2023 Aug 21.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Monoamine Oxidase Inhibitors*/adverse effects
Tyramine*/pharmacology
Humans ; Monoamine Oxidase/pharmacology ; Blood Pressure

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Skocz do pozycji: 6.

Tytuł:: ( S )- N -Benzyl-1-phenyl-3,4-dihydroisoqunoline-2(1 H )-carboxamide Derivatives, Multi-Target Inhibitors of Monoamine Oxidase and Cholinesterase: Design, Synthesis, and Biological Activity.
Autorzy:: Jin QH; College of Nursing, Zhejiang Pharmaceutical University, Ningbo 315153, China.
Zhang LP; College of Nursing, Zhejiang Pharmaceutical University, Ningbo 315153, China.
Zhang SS; Food and Pharmacy College, Zhejiang Ocean University, Zhoushan 316022, China.
Zhuang DN; College of Nursing, Zhejiang Pharmaceutical University, Ningbo 315153, China.
Zhang CY; College of Nursing, Zhejiang Pharmaceutical University, Ningbo 315153, China.
Zheng ZJ; College of Nursing, Zhejiang Pharmaceutical University, Ningbo 315153, China.
Guan LP; Food and Pharmacy College, Zhejiang Ocean University, Zhoushan 316022, China.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2023 Feb 09; Vol. 28 (4). Date of Electronic Publication: 2023 Feb 09.
Typ publikacji:: Journal Article
MeSH Terms:: Monoamine Oxidase*/metabolism
Cholinesterases*/metabolism
Monoamine Oxidase Inhibitors/pharmacology ; Molecular Docking Simulation ; Structure-Activity Relationship ; Cholinesterase Inhibitors/chemistry ; Acetylcholinesterase/metabolism

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Skocz do pozycji: 7.

Tytuł:: Synthesis of Novel Benzo[ b ][1,6]naphthyridine Derivatives and Investigation of Their Potential as Scaffolds of MAO Inhibitors.
Autorzy:: Kulikova LN; Organic Chemistry Department, Peoples' Friendship University of Russia (RUDN University), Miklukho-Maklaya St. 6., 117198 Moscow, Russia.
Raesi GR; Organic Chemistry Department, Peoples' Friendship University of Russia (RUDN University), Miklukho-Maklaya St. 6., 117198 Moscow, Russia.
Levickaya DD; Organic Chemistry Department, Peoples' Friendship University of Russia (RUDN University), Miklukho-Maklaya St. 6., 117198 Moscow, Russia.
Purgatorio R; Department of Pharmacy-Pharmaceutical Sciences, University of Bari Aldo Moro, Via E. Orabona 4, 70125 Bari, Italy.
Spada G; Department of Pharmacy-Pharmaceutical Sciences, University of Bari Aldo Moro, Via E. Orabona 4, 70125 Bari, Italy.
Catto M; Department of Pharmacy-Pharmaceutical Sciences, University of Bari Aldo Moro, Via E. Orabona 4, 70125 Bari, Italy.
Altomare CD; Department of Pharmacy-Pharmaceutical Sciences, University of Bari Aldo Moro, Via E. Orabona 4, 70125 Bari, Italy.
Voskressensky LG; Organic Chemistry Department, Peoples' Friendship University of Russia (RUDN University), Miklukho-Maklaya St. 6., 117198 Moscow, Russia.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2023 Feb 09; Vol. 28 (4). Date of Electronic Publication: 2023 Feb 09.
Typ publikacji:: Journal Article
MeSH Terms:: Monoamine Oxidase Inhibitors*/pharmacology
Pargyline*
Monoamine Oxidase/metabolism ; Naphthyridines ; Structure-Activity Relationship

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Skocz do pozycji: 8.

Tytuł:: Medicarpin and Homopterocarpin Isolated from Canavalia lineata as Potent and Competitive Reversible Inhibitors of Human Monoamine Oxidase-B.
Autorzy:: Oh JM; Department of Pharmacy, and Research Institute of Life Pharmaceutical Sciences, Sunchon National University, Suncheon 57922, Republic of Korea.
Jang HJ; Natural Product Research Center, Korea Research Institute of Bioscience and Biotechnology, Cheongju 28116, Republic of Korea.
Kang MG; Department of Predictive Toxicology, Korea Institute of Toxicology, Daejeon 34114, Republic of Korea.
Mun SK; Department of Pharmacy, and Research Institute of Life Pharmaceutical Sciences, Sunchon National University, Suncheon 57922, Republic of Korea.
Park D; Department of Predictive Toxicology, Korea Institute of Toxicology, Daejeon 34114, Republic of Korea.
Hong SJ; Natural Product Research Center, Korea Research Institute of Bioscience and Biotechnology, Cheongju 28116, Republic of Korea.
Kim MH; National Institute of Biological Resources, Environmental Research Complex, Incheon 22689, Republic of Korea.
Kim SY; National Institute of Biological Resources, Environmental Research Complex, Incheon 22689, Republic of Korea.
Yee ST; Department of Pharmacy, and Research Institute of Life Pharmaceutical Sciences, Sunchon National University, Suncheon 57922, Republic of Korea.
Kim H; Department of Pharmacy, and Research Institute of Life Pharmaceutical Sciences, Sunchon National University, Suncheon 57922, Republic of Korea.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2022 Dec 28; Vol. 28 (1). Date of Electronic Publication: 2022 Dec 28.
Typ publikacji:: Journal Article
MeSH Terms:: Monoamine Oxidase Inhibitors*/chemistry
Neuroblastoma*
Humans ; Canavalia ; Molecular Docking Simulation ; Monoamine Oxidase/metabolism ; Structure-Activity Relationship

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Skocz do pozycji: 9.

Tytuł:: N -Hydroxy- N -Propargylamide Derivatives of Ferulic Acid: Inhibitors of Cholinesterases and Monoamine Oxidases.
Autorzy:: Bautista-Aguilera ÓM; Universidad de Alcalá, Departamento de Química Orgánica y Química Inorgánica, Ctra, Madrid-Barcelona Km 33.6, 28871 Alcalá de Henares, Madrid, Spain.
Alonso JM; Universidad de Alcalá, Departamento de Química Orgánica y Química Inorgánica, Ctra, Madrid-Barcelona Km 33.6, 28871 Alcalá de Henares, Madrid, Spain.
Catto M; Department of Pharmacy-Pharmaceutical Sciences, University of Bari Aldo Moro, Via E. Orabona 4, 70125 Bari, Italy.
Iriepa I; Universidad de Alcalá, Departamento de Química Orgánica y Química Inorgánica, Ctra, Madrid-Barcelona Km 33.6, 28871 Alcalá de Henares, Madrid, Spain.; Institute of Chemical Research Andrés M. del Río, Alcalá University, 28805 Alcalá de Henares, Madrid, Spain.
Knez D; University of Ljubljana, Faculty of Pharmacy, Askerceva 7, 1000 Ljubljana, Slovenia.
Gobec S; University of Ljubljana, Faculty of Pharmacy, Askerceva 7, 1000 Ljubljana, Slovenia.
Marco-Contelles J; Laboratory of Medicinal Chemistry (IQOG, CSIC), C/Juan de la Cierva 3, 28006 Madrid, Spain.; Center for Biomedical Network Research on Rare Diseases (CIBERER), CIBER, ISCIII, 28029 Madrid, Spain.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2022 Nov 01; Vol. 27 (21). Date of Electronic Publication: 2022 Nov 01.
Typ publikacji:: Journal Article
MeSH Terms:: Monoamine Oxidase*/metabolism
Alzheimer Disease*/metabolism
Humans ; Cholinesterases/metabolism ; Amyloid beta-Peptides/metabolism ; Monoamine Oxidase Inhibitors/chemistry ; Cholinesterase Inhibitors/chemistry ; Ligands ; Antioxidants/chemistry ; Acetylcholinesterase/metabolism

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Skocz do pozycji: 10.

Tytuł:: Synthesis, Characterization and Biological Evaluation of Benzothiazole-Isoquinoline Derivative.
Autorzy:: Liu W; Food and Pharmacy College, Zhejiang Ocean University, Zhoushan 316022, China.
Zhao D; Pharmacy College, Jilin Medical University, Jilin 132013, China.
He Z; Food and Pharmacy College, Zhejiang Ocean University, Zhoushan 316022, China.
Hu Y; Food and Pharmacy College, Zhejiang Ocean University, Zhoushan 316022, China.
Zhu Y; Food and Pharmacy College, Zhejiang Ocean University, Zhoushan 316022, China.
Zhang L; Food and Pharmacy College, Zhejiang Ocean University, Zhoushan 316022, China.
Jin L; Pharmacy College, Jilin Medical University, Jilin 132013, China.
Guan L; Food and Pharmacy College, Zhejiang Ocean University, Zhoushan 316022, China.
Wang S; Key Laboratory of Natural Resource of the Changbai Mountain and Functiaonal Molecules, Ministry of Education, Yanbian University, Yanji 133000, China.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2022 Dec 19; Vol. 27 (24). Date of Electronic Publication: 2022 Dec 19.
Typ publikacji:: Journal Article
MeSH Terms:: Monoamine Oxidase Inhibitors*/pharmacology
Butyrylcholinesterase*/metabolism
Humans ; Structure-Activity Relationship ; Molecular Docking Simulation ; Monoamine Oxidase/metabolism ; Benzothiazoles/pharmacology ; Isoquinolines ; Cholinesterase Inhibitors/pharmacology ; Molecular Structure

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Skocz do pozycji: 11.

Tytuł:: Natural source, bioactivity and synthesis of 3-Arylcoumarin derivatives.
Autorzy:: Zhang Q; Institute of Materia Medica, Shandong First Medical University, Shandong Academy of Medical Sciences, Jinan, Shandong, China.
Miao YH; Institute of Materia Medica, Shandong First Medical University, Shandong Academy of Medical Sciences, Jinan, Shandong, China.
Liu T; Institute of Materia Medica, Shandong First Medical University, Shandong Academy of Medical Sciences, Jinan, Shandong, China.
Yun YL; Institute of Materia Medica, Shandong First Medical University, Shandong Academy of Medical Sciences, Jinan, Shandong, China.
Sun XY; Institute of Materia Medica, Shandong First Medical University, Shandong Academy of Medical Sciences, Jinan, Shandong, China.
Yang T; Department of Thoracic and Cardiovascular Surgery, First Affiliated Hospital of Chongqing Medical University, Chongqing, Chongqing, China.
Sun J; Institute of Materia Medica, Shandong First Medical University, Shandong Academy of Medical Sciences, Jinan, Shandong, China.; Pokaż więcej
Źródło:: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2022 Dec; Vol. 37 (1), pp. 1023-1042.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Coumarins*/chemistry
Monoamine Oxidase Inhibitors*/chemistry
Antioxidants/chemistry ; Monoamine Oxidase/metabolism ; Structure-Activity Relationship

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Skocz do pozycji: 12.

Tytuł:: Discovery of MAO-B Inhibitor with Machine Learning, Topomer CoMFA, Molecular Docking and Multi-Spectroscopy Approaches.
Autorzy:: Zheng L; School of Life Science, Shanghai University, Shanghai 200444, China.; Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China.
Qin X; Department of Chemistry, School of Pharmacy, Air Force Medical University, Xi'an 710032, China.
Wang J; School of Life Science, Shanghai University, Shanghai 200444, China.
Zhang M; School of Life Science, Shanghai University, Shanghai 200444, China.
An Q; Institute of Clinical Science, Zhongshan Hospital, Shanghai Medical College, Fudan University, Shanghai 200444, China.
Xu J; Institute of Clinical Science, Zhongshan Hospital, Shanghai Medical College, Fudan University, Shanghai 200444, China.
Qu X; National Engineering Laboratory of Southwest Endangered Medicinal Resources Development, Guangxi Botanical Garden of Medicinal Plants, Nanning 530023, China.
Cao X; Institute of Clinical Science, Zhongshan Hospital, Shanghai Medical College, Fudan University, Shanghai 200444, China.
Niu B; School of Life Science, Shanghai University, Shanghai 200444, China.; Pokaż więcej
Źródło:: Biomolecules [Biomolecules] 2022 Oct 13; Vol. 12 (10). Date of Electronic Publication: 2022 Oct 13.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Monoamine Oxidase Inhibitors*/pharmacology
Monoamine Oxidase Inhibitors*/chemistry
Alzheimer Disease*/drug therapy
Humans ; Molecular Docking Simulation ; Monoamine Oxidase/chemistry ; Spectrum Analysis ; Machine Learning

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Skocz do pozycji: 13.

Tytuł:: Computational Insights into β-Carboline Inhibition of Monoamine Oxidase A.
Autorzy:: Prah A; National Institute of Chemistry, SI-1000 Ljubljana, Slovenia.; Jožef Stefan Institute, SI-1000 Ljubljana, Slovenia.
Gavranić T; National Institute of Chemistry, SI-1000 Ljubljana, Slovenia.; Faculty of Pharmacy, University of Ljubljana, SI-1000 Ljubljana, Slovenia.
Perdih A; National Institute of Chemistry, SI-1000 Ljubljana, Slovenia.; Faculty of Pharmacy, University of Ljubljana, SI-1000 Ljubljana, Slovenia.
Sollner Dolenc M; Faculty of Pharmacy, University of Ljubljana, SI-1000 Ljubljana, Slovenia.
Mavri J; National Institute of Chemistry, SI-1000 Ljubljana, Slovenia.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2022 Oct 09; Vol. 27 (19). Date of Electronic Publication: 2022 Oct 09.
Typ publikacji:: Journal Article
MeSH Terms:: Monoamine Oxidase Inhibitors*/chemistry
Monoamine Oxidase Inhibitors*/pharmacology
Tobacco Smoke Pollution*
Carbolines/pharmacology ; Coffee ; Humans ; Molecular Docking Simulation ; Monoamine Oxidase/metabolism ; Structure-Activity Relationship

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Skocz do pozycji: 14.

Tytuł:: Synthesis of Isomeric 3-Benzazecines Decorated with Endocyclic Allene Moiety and Exocyclic Conjugated Double Bond and Evaluation of Their Anticholinesterase Activity.
Autorzy:: Titov AA; Organic Chemistry Department, Peoples' Friendship University of Russia (RUDN University), 6 Miklukho-Maklaya St, Moscow 117198, Russia.
Purgatorio R; Department of Pharmacy-Pharmaceutical Sciences, University of Bari Aldo Moro, Via E. Orabona 4, 70125 Bari, Italy.
Obydennik AY; Organic Chemistry Department, Peoples' Friendship University of Russia (RUDN University), 6 Miklukho-Maklaya St, Moscow 117198, Russia.
Listratova AV; Organic Chemistry Department, Peoples' Friendship University of Russia (RUDN University), 6 Miklukho-Maklaya St, Moscow 117198, Russia.
Borisova TN; Organic Chemistry Department, Peoples' Friendship University of Russia (RUDN University), 6 Miklukho-Maklaya St, Moscow 117198, Russia.
de Candia M; Department of Pharmacy-Pharmaceutical Sciences, University of Bari Aldo Moro, Via E. Orabona 4, 70125 Bari, Italy.
Catto M; Department of Pharmacy-Pharmaceutical Sciences, University of Bari Aldo Moro, Via E. Orabona 4, 70125 Bari, Italy.
Altomare CD; Department of Pharmacy-Pharmaceutical Sciences, University of Bari Aldo Moro, Via E. Orabona 4, 70125 Bari, Italy.
Varlamov AV; Organic Chemistry Department, Peoples' Friendship University of Russia (RUDN University), 6 Miklukho-Maklaya St, Moscow 117198, Russia.
Voskressensky LG; Organic Chemistry Department, Peoples' Friendship University of Russia (RUDN University), 6 Miklukho-Maklaya St, Moscow 117198, Russia.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2022 Sep 23; Vol. 27 (19). Date of Electronic Publication: 2022 Sep 23.
Typ publikacji:: Journal Article
MeSH Terms:: Cholinesterase Inhibitors*/chemistry
Monoamine Oxidase Inhibitors*/chemistry
Acetylcholinesterase/metabolism ; Alcohols ; Alkadienes ; Alkynes ; Butyrylcholinesterase/chemistry ; Humans ; Isoquinolines ; Molecular Docking Simulation ; Molecular Structure ; Monoamine Oxidase/metabolism ; Structure-Activity Relationship ; Water

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Skocz do pozycji: 15.

Tytuł:: Screening of Big Pharma's Library against Various in-house Biological Targets.
Autorzy:: Knez D; Faculty of Pharmacy, University of Ljubljana, Aškerčeva 7, SI 1000 Ljubljana, Slovenia.
Gobec S; Faculty of Pharmacy, University of Ljubljana, Aškerčeva 7, SI 1000 Ljubljana, Slovenia.
Hrast M; Faculty of Pharmacy, University of Ljubljana, Aškerčeva 7, SI 1000 Ljubljana, Slovenia.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2022 Jul 13; Vol. 27 (14). Date of Electronic Publication: 2022 Jul 13.
Typ publikacji:: Journal Article
MeSH Terms:: Enzyme Inhibitors*/pharmacology
Monoamine Oxidase*/metabolism
Animals ; Cholinesterase Inhibitors/chemistry ; Humans ; Mice ; Monoamine Oxidase Inhibitors/chemistry ; Research ; Structure-Activity Relationship

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Skocz do pozycji: 16.

Tytuł:: Design, synthesis, and evaluation of chalcone-Vitamin E-donepezil hybrids as multi-target-directed ligands for the treatment of Alzheimer's disease.
Autorzy:: Sang Z; College of Chemistry and Pharmaceutical Engineering, Nanyang Normal University, Nanyang, China.; Department of Medicinal Chemistry, West China School of Pharmacy, Sichuan University, Chengdu, China.
Song Q; Department of Medicinal Chemistry, West China School of Pharmacy, Sichuan University, Chengdu, China.
Cao Z; Department of Medicinal Chemistry, West China School of Pharmacy, Sichuan University, Chengdu, China.
Deng Y; Department of Medicinal Chemistry, West China School of Pharmacy, Sichuan University, Chengdu, China.
Zhang L; Department of Elderly Digestive, Sichuan Academy of Medical Sciences, Sichuan Provincial People's Hospital, Chengdu, China.; Pokaż więcej
Źródło:: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2022 Dec; Vol. 37 (1), pp. 69-85.
Typ publikacji:: Journal Article
MeSH Terms:: Drug Design*
Alzheimer Disease/*drug therapy
Antioxidants/*pharmacology
Cholinesterase Inhibitors/*pharmacology
Monoamine Oxidase Inhibitors/*pharmacology
Neuroprotective Agents/*pharmacology
Acetylcholinesterase/metabolism ; Alzheimer Disease/metabolism ; Amyloid beta-Peptides/antagonists & inhibitors ; Amyloid beta-Peptides/metabolism ; Animals ; Antioxidants/chemical synthesis ; Antioxidants/chemistry ; Chalcone/chemistry ; Chalcone/pharmacology ; Cholinesterase Inhibitors/chemical synthesis ; Cholinesterase Inhibitors/chemistry ; Dose-Response Relationship, Drug ; Electrophorus ; Humans ; Ligands ; Molecular Structure ; Monoamine Oxidase/metabolism ; Monoamine Oxidase Inhibitors/chemical synthesis ; Monoamine Oxidase Inhibitors/chemistry ; Neuroprotective Agents/chemical synthesis ; Neuroprotective Agents/chemistry ; PC12 Cells ; Protein Aggregates/drug effects ; Rats ; Structure-Activity Relationship ; Vitamin E/chemistry ; Vitamin E/pharmacology

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Skocz do pozycji: 17.

Tytuł:: Microbial Metabolites of 3- n -butylphthalide as Monoamine Oxidase A Inhibitors.
Autorzy:: Gach J; Department of Food Chemistry and Biocatalysis, Wrocław University of Environmental and Life Sciences, Norwida 25, 50-375 Wrocław, Poland.
Grzelczyk J; Institute of Food Technology and Analysis, Faculty of Biotechnology and Food Sciences, Lodz University of Technology, Stefanowskiego 2/22, 90-924 Łódź, Poland.
Strzała T; Department of Genetics, Wrocław University of Environmental and Life Sciences, Kożuchowska 7, 51-631 Wrocław, Poland.
Boratyński F; Department of Food Chemistry and Biocatalysis, Wrocław University of Environmental and Life Sciences, Norwida 25, 50-375 Wrocław, Poland.
Olejniczak T; Department of Food Chemistry and Biocatalysis, Wrocław University of Environmental and Life Sciences, Norwida 25, 50-375 Wrocław, Poland.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Jun 25; Vol. 24 (13). Date of Electronic Publication: 2023 Jun 25.
Typ publikacji:: Journal Article
MeSH Terms:: Monoamine Oxidase Inhibitors*/pharmacology
Monoamine Oxidase Inhibitors*/chemistry
Monoamine Oxidase*/metabolism
Antidepressive Agents ; Lactones

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Skocz do pozycji: 18.

Tytuł:: New Insights on the Activity and Selectivity of MAO-B Inhibitors through In Silico Methods.
Autorzy:: Pacureanu L; 'Coriolan Dragulescu' Institute of Chemistry, 24 Mihai Viteazu Ave., 300223 Timisoara, Romania.
Bora A; 'Coriolan Dragulescu' Institute of Chemistry, 24 Mihai Viteazu Ave., 300223 Timisoara, Romania.
Crisan L; 'Coriolan Dragulescu' Institute of Chemistry, 24 Mihai Viteazu Ave., 300223 Timisoara, Romania.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 May 31; Vol. 24 (11). Date of Electronic Publication: 2023 May 31.
Typ publikacji:: Journal Article
MeSH Terms:: Monoamine Oxidase Inhibitors*/pharmacology
Monoamine Oxidase Inhibitors*/chemistry
Monoamine Oxidase*/metabolism
Molecular Docking Simulation ; Quantitative Structure-Activity Relationship ; Pharmacophore ; Structure-Activity Relationship

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Tytuł:: Structure-Based Design of Novel MAO-B Inhibitors: A Review.
Autorzy:: Mateev E; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Medical University-Sofia, 1000 Sofia, Bulgaria.
Georgieva M; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Medical University-Sofia, 1000 Sofia, Bulgaria.
Mateeva A; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Medical University-Sofia, 1000 Sofia, Bulgaria.
Zlatkov A; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Medical University-Sofia, 1000 Sofia, Bulgaria.
Ahmad S; Department of Computer Science, Jamia Millia Islamia, New Delhi 110025, India.
Raza K; Department of Computer Science, Jamia Millia Islamia, New Delhi 110025, India.
Azevedo V; Departamento de Genetica, Ecologia e Evolucao, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Brazil.
Barh D; Departamento de Genetica, Ecologia e Evolucao, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Brazil.; Institute of Integrative Omics and Applied Biotechnology (IIOAB), Nonakuri, Purba Medinipur 721172, India.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2023 Jun 16; Vol. 28 (12). Date of Electronic Publication: 2023 Jun 16.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Monoamine Oxidase Inhibitors*/pharmacology
Monoamine Oxidase Inhibitors*/chemistry
Monoamine Oxidase*/metabolism
Humans ; Molecular Docking Simulation ; Drug Discovery ; Drug Design ; Structure-Activity Relationship

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Skocz do pozycji: 20.

Tytuł:: Machine learning driven web-based app platform for the discovery of monoamine oxidase B inhibitors.
Autorzy:: Kumar S; Department of Pharmaceutical Chemistry, Amrita School of Pharmacy, Amrita Vishwa Vidyapeetham, AIMS Health Sciences Campus, Kochi, India.
Bhowmik R; Department of Pharmaceutical Chemistry, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi, India.
Oh JM; Department of Pharmacy, and Research Institute of Life Pharmaceutical Sciences, Sunchon National University, Suncheon, 57922, Republic of Korea.
Abdelgawad MA; Department of Pharmaceutical Chemistry, College of Pharmacy, Jouf University, 72341, Sakaka, Aljouf, Saudi Arabia.
Ghoneim MM; Department of Pharmacy Practice, College of Pharmacy, AlMaarefa University, 13713, Ad Diriyah, Riyadh, Saudi Arabia.
Al-Serwi RH; Department of Basic Dental Sciences, College of Dentistry, Princess Nourah Bint Abdulrahman University, P.O. Box 84428, 11671, Riyadh, Saudi Arabia.
Kim H; Department of Pharmacy, and Research Institute of Life Pharmaceutical Sciences, Sunchon National University, Suncheon, 57922, Republic of Korea. .
Mathew B; Department of Pharmaceutical Chemistry, Amrita School of Pharmacy, Amrita Vishwa Vidyapeetham, AIMS Health Sciences Campus, Kochi, India. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Feb 28; Vol. 14 (1), pp. 4868. Date of Electronic Publication: 2024 Feb 28.
Typ publikacji:: Journal Article
MeSH Terms:: Mobile Applications*
Neurodegenerative Diseases*/drug therapy
Humans ; Molecular Docking Simulation ; Monoamine Oxidase/metabolism ; Monoamine Oxidase Inhibitors/chemistry ; Dopamine Agents/pharmacology ; Internet ; Structure-Activity Relationship

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