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Tytuł :
Myeloid Mineralocorticoid Receptor Transcriptionally Regulates P-Selectin Glycoprotein Ligand-1 and Promotes Monocyte Trafficking and Atherosclerosis.
Autorzy :
Man JJ; Molecular Cardiology Research Institute (J.J.M., Q.L., M.E.M., B.C., W.B., I.Z.J.), Tufts University School of Medicine, Boston, MA.; Graduate School of Biomedical Sciences (J.J.M., M.E.M.), Tufts University School of Medicine, Boston, MA.
Lu Q; Molecular Cardiology Research Institute (J.J.M., Q.L., M.E.M., B.C., W.B., I.Z.J.), Tufts University School of Medicine, Boston, MA.
Moss ME; Molecular Cardiology Research Institute (J.J.M., Q.L., M.E.M., B.C., W.B., I.Z.J.), Tufts University School of Medicine, Boston, MA.; Graduate School of Biomedical Sciences (J.J.M., M.E.M.), Tufts University School of Medicine, Boston, MA.
Carvajal B; Molecular Cardiology Research Institute (J.J.M., Q.L., M.E.M., B.C., W.B., I.Z.J.), Tufts University School of Medicine, Boston, MA.
Baur W; Molecular Cardiology Research Institute (J.J.M., Q.L., M.E.M., B.C., W.B., I.Z.J.), Tufts University School of Medicine, Boston, MA.
Garza AE; Division of Endocrinology, Diabetes and Hypertension, Brigham and Women's Hospital (A.E.G., G.K.A.), Harvard Medical School, Boston, MA.
Freeman R; Department of Neurology, Beth Israel Deaconess Medical Center (R.F.), Harvard Medical School, Boston, MA.
Anastasiou M; Department of Immunology (M.A., N.N., P.A.), Tufts University School of Medicine, Boston, MA.; Department of Internal Medicine, University of Crete Medical School, Greece (M.A.).
Ngwenyama N; Department of Immunology (M.A., N.N., P.A.), Tufts University School of Medicine, Boston, MA.
Adler GK; Division of Endocrinology, Diabetes and Hypertension, Brigham and Women's Hospital (A.E.G., G.K.A.), Harvard Medical School, Boston, MA.
Alcaide P; Department of Immunology (M.A., N.N., P.A.), Tufts University School of Medicine, Boston, MA.
Jaffe IZ; Molecular Cardiology Research Institute (J.J.M., Q.L., M.E.M., B.C., W.B., I.Z.J.), Tufts University School of Medicine, Boston, MA.
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Źródło :
Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2021 Nov; Vol. 41 (11), pp. 2740-2755. Date of Electronic Publication: 2021 Oct 07.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Video-Audio Media
MeSH Terms :
Cell Adhesion*/drug effects
Leukocyte Rolling*/drug effects
Aorta, Thoracic/*metabolism
Aortic Diseases/*metabolism
Atherosclerosis/*metabolism
Macrophages, Peritoneal/*metabolism
Membrane Glycoproteins/*metabolism
Monocytes/*metabolism
Receptors, Mineralocorticoid/*metabolism
Adult ; Animals ; Aorta, Thoracic/pathology ; Aortic Diseases/genetics ; Aortic Diseases/pathology ; Aortic Diseases/prevention & control ; Atherosclerosis/genetics ; Atherosclerosis/pathology ; Atherosclerosis/prevention & control ; Disease Models, Animal ; Female ; HEK293 Cells ; Humans ; Hypoglycemia/drug therapy ; Hypoglycemia/genetics ; Hypoglycemia/metabolism ; Macrophages, Peritoneal/pathology ; Male ; Membrane Glycoproteins/genetics ; Mice, Inbred C57BL ; Mice, Knockout, ApoE ; Middle Aged ; Mineralocorticoid Receptor Antagonists/therapeutic use ; Monocytes/drug effects ; Monocytes/pathology ; Randomized Controlled Trials as Topic ; Receptors, Mineralocorticoid/drug effects ; Receptors, Mineralocorticoid/genetics ; Sex Factors ; Signal Transduction ; Spironolactone/therapeutic use ; Transcription, Genetic ; Transendothelial and Transepithelial Migration ; Treatment Outcome ; U937 Cells ; Young Adult
Czasopismo naukowe
Tytuł :
Differential response of immobile (pneumocytes) and mobile (monocytes) barriers against 2 types of metal oxide nanoparticles.
Autorzy :
Ispanixtlahuatl-Meráz O; Unidad de Biomedicina, Facultad de Estudios Superiores Iztacala, Universidad Nacional Autónoma de México, Av. de los Barrios No. 1, Tlalnepantla de Baz, CP, 54090, Estado de México, Mexico; Programa de Doctorado en Ciencias Biomédicas, Unidad de Posgrado Edificio B Primer Piso Ciudad Universitaria, Coyoacán, CP, 04510, Ciudad de México, Mexico.
Delgado-Buenrostro NL; Unidad de Biomedicina, Facultad de Estudios Superiores Iztacala, Universidad Nacional Autónoma de México, Av. de los Barrios No. 1, Tlalnepantla de Baz, CP, 54090, Estado de México, Mexico.
Déciga-Alcaraz A; Unidad de Biomedicina, Facultad de Estudios Superiores Iztacala, Universidad Nacional Autónoma de México, Av. de los Barrios No. 1, Tlalnepantla de Baz, CP, 54090, Estado de México, Mexico; Programa de Doctorado en Ciencias Biomédicas, Unidad de Posgrado Edificio B Primer Piso Ciudad Universitaria, Coyoacán, CP, 04510, Ciudad de México, Mexico.
Ramos-Godinez MDP; Unidad de Microscopía Avanzada, Instituto Nacional de Cancerología, RAI, UNAM, Mexico.
Oliva-Rico D; Unidad de Microscopía Avanzada, Instituto Nacional de Cancerología, RAI, UNAM, Mexico.
López-Villegas EO; Departamento de Graduados e Investigación en Alimentos, Departamento de Ingeniería Bioquímica, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, CP, 11340, Ciudad de México, Mexico.
Vázquez-Zapién GJ; Escuela Militar de Medicina, Centro Militar de Ciencias de la Salud, Secretaría de la Defensa Nacional, Cerrada de Palomas S/N, Lomas de San Isidro, Alcaldía Miguel Hidalgo, CP, 11200, Ciudad de México, Mexico.
Mata-Miranda MM; Escuela Militar de Medicina, Centro Militar de Ciencias de la Salud, Secretaría de la Defensa Nacional, Cerrada de Palomas S/N, Lomas de San Isidro, Alcaldía Miguel Hidalgo, CP, 11200, Ciudad de México, Mexico.
Ilhuicatzi-Alvarado D; Unidad de Biomedicina, Facultad de Estudios Superiores Iztacala, Universidad Nacional Autónoma de México, Av. de los Barrios No. 1, Tlalnepantla de Baz, CP, 54090, Estado de México, Mexico.
Moreno-Fierros L; Unidad de Biomedicina, Facultad de Estudios Superiores Iztacala, Universidad Nacional Autónoma de México, Av. de los Barrios No. 1, Tlalnepantla de Baz, CP, 54090, Estado de México, Mexico.
García Cuellar CM; Subdirección de Investigación Básica, Instituto Nacional de Cancerología, San Fernando No. 22, Tlalpan, CP, 14080, Cuidad de México, Mexico.
Sánchez-Pérez Y; Subdirección de Investigación Básica, Instituto Nacional de Cancerología, San Fernando No. 22, Tlalpan, CP, 14080, Cuidad de México, Mexico.
Chirino YI; Unidad de Biomedicina, Facultad de Estudios Superiores Iztacala, Universidad Nacional Autónoma de México, Av. de los Barrios No. 1, Tlalnepantla de Baz, CP, 54090, Estado de México, Mexico. Electronic address: .
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Źródło :
Chemico-biological interactions [Chem Biol Interact] 2021 Sep 25; Vol. 347, pp. 109596. Date of Electronic Publication: 2021 Jul 28.
Typ publikacji :
Journal Article
MeSH Terms :
Alveolar Epithelial Cells/*drug effects
Metal Nanoparticles/*toxicity
Monocytes/*drug effects
Actin Cytoskeleton/metabolism ; Alveolar Epithelial Cells/chemistry ; Alveolar Epithelial Cells/metabolism ; Cell Line, Tumor ; Cell Survival/drug effects ; Humans ; Metal Nanoparticles/chemistry ; Monocytes/chemistry ; Monocytes/metabolism ; Spectroscopy, Fourier Transform Infrared ; Tin Compounds/chemistry ; Tin Compounds/pharmacology ; Tin Compounds/toxicity ; Titanium/chemistry ; Titanium/pharmacology ; Titanium/toxicity ; Vacuoles/metabolism
Czasopismo naukowe
Tytuł :
Lysophosphatidylglucoside is a GPR55 -mediated chemotactic molecule for human monocytes and macrophages.
Autorzy :
Li X; Institute for Environmental and Gender-Specific Medicine, Juntendo University Graduate School of Medicine, Urayasu, Chiba 279-0021, Japan.
Hanafusa K; Institute for Environmental and Gender-Specific Medicine, Juntendo University Graduate School of Medicine, Urayasu, Chiba 279-0021, Japan.
Kage M; Institute for Environmental and Gender-Specific Medicine, Juntendo University Graduate School of Medicine, Urayasu, Chiba 279-0021, Japan.
Yokoyama N; Institute for Environmental and Gender-Specific Medicine, Juntendo University Graduate School of Medicine, Urayasu, Chiba 279-0021, Japan.
Nakayama H; Institute for Environmental and Gender-Specific Medicine, Juntendo University Graduate School of Medicine, Urayasu, Chiba 279-0021, Japan; Infection Control Nursing, Juntendo University Graduate School of Health Care and Nursing, Urayasu, Chiba 279-0023, Japan.
Hotta T; Institute for Environmental and Gender-Specific Medicine, Juntendo University Graduate School of Medicine, Urayasu, Chiba 279-0021, Japan.
Oshima E; Institute for Environmental and Gender-Specific Medicine, Juntendo University Graduate School of Medicine, Urayasu, Chiba 279-0021, Japan.
Kano K; Division of Molecular Science, Gunma University, Kiryu, Gunma 376-8515, Japan.
Matsuo I; Division of Molecular Science, Gunma University, Kiryu, Gunma 376-8515, Japan.
Nagatsuka Y; Cellular Informatics Laboratory, RIKEN, 2-1, Hirosawa, Wako, Saitama 351-0198, Japan.
Takamori K; Institute for Environmental and Gender-Specific Medicine, Juntendo University Graduate School of Medicine, Urayasu, Chiba 279-0021, Japan.
Ogawa H; Institute for Environmental and Gender-Specific Medicine, Juntendo University Graduate School of Medicine, Urayasu, Chiba 279-0021, Japan.
Hirabayashi Y; Institute for Environmental and Gender-Specific Medicine, Juntendo University Graduate School of Medicine, Urayasu, Chiba 279-0021, Japan; Cellular Informatics Laboratory, RIKEN, 2-1, Hirosawa, Wako, Saitama 351-0198, Japan.
Iwabuchi K; Institute for Environmental and Gender-Specific Medicine, Juntendo University Graduate School of Medicine, Urayasu, Chiba 279-0021, Japan; Infection Control Nursing, Juntendo University Graduate School of Health Care and Nursing, Urayasu, Chiba 279-0023, Japan. Electronic address: .
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2021 Sep 10; Vol. 569, pp. 86-92. Date of Electronic Publication: 2021 Jul 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Movement/*drug effects
Glucosides/*pharmacology
Lysophospholipids/*chemistry
Macrophages/*drug effects
Monocytes/*drug effects
Receptors, Cannabinoid/*metabolism
Blotting, Western ; Cell Movement/genetics ; Chemotaxis/drug effects ; Chemotaxis/physiology ; Glucosides/chemistry ; Humans ; Lysophospholipids/pharmacology ; Macrophages/cytology ; Macrophages/metabolism ; Monocytes/cytology ; Monocytes/metabolism ; RNA Interference ; Receptors, Cannabinoid/genetics ; THP-1 Cells
Czasopismo naukowe
Tytuł :
Impact of cholesterol on proinflammatory monocyte production by the bone marrow.
Autorzy :
Stiekema LCA; Department of Vascular Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam Cardiovascular Sciences, Meibergdreef 9, Amsterdam 1105 AZ, The Netherlands.
Willemsen L; Department of Medical Biochemistry, Amsterdam UMC, University of Amsterdam, Amsterdam Cardiovascular Sciences, Meibergdreef 9, Amsterdam 1105 AZ, The Netherlands.
Kaiser Y; Department of Vascular Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam Cardiovascular Sciences, Meibergdreef 9, Amsterdam 1105 AZ, The Netherlands.
Prange KHM; Department of Medical Biochemistry, Amsterdam UMC, University of Amsterdam, Amsterdam Cardiovascular Sciences, Meibergdreef 9, Amsterdam 1105 AZ, The Netherlands.
Wareham NJ; Medical Research Council Epidemiology Unit, University of Cambridge, Cambridge CB2 0QQ, UK.
Boekholdt SM; Amsterdam UMC, University of Amsterdam, Department of Cardiology, Amsterdam Cardiovascular Sciences, Meibergdreef 9, Amsterdam 1105 AZ, The Netherlands.
Kuijk C; Sanquin Research and Landsteiner Laboratory, Department of Hematopoiesis, University of Amsterdam, Plesmanlaan 125, Amsterdam 1066 CX, The Netherlands.
de Winther MPJ; Department of Medical Biochemistry, Amsterdam UMC, University of Amsterdam, Amsterdam Cardiovascular Sciences, Meibergdreef 9, Amsterdam 1105 AZ, The Netherlands.; Department of Medical Biochemistry, Amsterdam UMC, University of Amsterdam, Amsterdam Infection and Immunity, Meibergdreef 9, Amsterdam 1105 AZ, The Netherlands.
Voermans C; Sanquin Research and Landsteiner Laboratory, Department of Hematopoiesis, University of Amsterdam, Plesmanlaan 125, Amsterdam 1066 CX, The Netherlands.
Nahrendorf M; Center for Systems Biology, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, 185 Cambridge Street, Boston, MA 02114, USA.
Stroes ESG; Department of Vascular Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam Cardiovascular Sciences, Meibergdreef 9, Amsterdam 1105 AZ, The Netherlands.
Kroon J; Department of Experimental Vascular Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam Cardiovascular Sciences, Meibergdreef 9, Amsterdam 1105 AZ, The Netherlands.
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Źródło :
European heart journal [Eur Heart J] 2021 Nov 07; Vol. 42 (42), pp. 4309-4320.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Bone Marrow*
Monocytes*
Cholesterol ; Hematopoiesis ; Humans ; Prospective Studies
Czasopismo naukowe
Tytuł :
High postoperative neutrophil-lymphocyte ratio and low preoperative lymphocyte-monocyte ratio predict poor prognosis in gastric cancer patients receiving gastrectomy with positive lavage cytology: a retrospective cohort study.
Autorzy :
Sato S; Department of Surgery, Gastroenterological Center, Yokohama City University, 4-57 Urafune-cho, Minami-ku, Yokohama City , Kanagawa, 232-0024, Japan.
Kunisaki C; Department of Surgery, Gastroenterological Center, Yokohama City University, 4-57 Urafune-cho, Minami-ku, Yokohama City , Kanagawa, 232-0024, Japan. .
Takahashi M; Department of Gastroenterological Surgery, Yokohama Municipal Citizen's Hospital, Yokohama City , Kanagawa, 236-0004, Japan.
Kubo H; Department of Surgery, Gastroenterological Center, Yokohama City University, 4-57 Urafune-cho, Minami-ku, Yokohama City , Kanagawa, 232-0024, Japan.
Tsuchiya N; Department of Surgery, Gastroenterological Center, Yokohama City University, 4-57 Urafune-cho, Minami-ku, Yokohama City , Kanagawa, 232-0024, Japan.
Sato K; Department of Surgery, Gastroenterological Center, Yokohama City University, 4-57 Urafune-cho, Minami-ku, Yokohama City , Kanagawa, 232-0024, Japan.
Miyamoto H; Department of Surgery, Gastroenterological Center, Yokohama City University, 4-57 Urafune-cho, Minami-ku, Yokohama City , Kanagawa, 232-0024, Japan.
Tamura Y; Department of Gastroenterological Surgery, Yokohama Municipal Citizen's Hospital, Yokohama City , Kanagawa, 236-0004, Japan.
Kondo H; Department of Gastroenterological Surgery, Yokohama Municipal Citizen's Hospital, Yokohama City , Kanagawa, 236-0004, Japan.
Tanaka Y; Department of Gastroenterological Surgery, Yokohama Municipal Citizen's Hospital, Yokohama City , Kanagawa, 236-0004, Japan.
Kasahara K; Department of Gastroenterological Surgery, Yokohama City University School of Medicine, Yokohama City, Kanagawa, 236-0004, Japan.
Kosaka T; Department of Gastroenterological Surgery, Yokohama City University School of Medicine, Yokohama City, Kanagawa, 236-0004, Japan.
Akiyama H; Department of Gastroenterological Surgery, Yokohama City University School of Medicine, Yokohama City, Kanagawa, 236-0004, Japan.
Saigusa Y; Department of Biostatistics, Yokohama City University School of Medicine, Yokohama City, Kanagawa, 236-0004, Japan.
Endo I; Department of Gastroenterological Surgery, Yokohama City University School of Medicine, Yokohama City, Kanagawa, 236-0004, Japan.
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Źródło :
Langenbeck's archives of surgery [Langenbecks Arch Surg] 2021 Nov; Vol. 406 (7), pp. 2295-2303. Date of Electronic Publication: 2021 Jun 17.
Typ publikacji :
Journal Article; Multicenter Study
MeSH Terms :
Lymphocytes*/cytology
Monocytes*/cytology
Neutrophils*/cytology
Stomach Neoplasms*/diagnosis
Stomach Neoplasms*/surgery
Gastrectomy ; Humans ; Prognosis ; Retrospective Studies ; Therapeutic Irrigation
Czasopismo naukowe
Tytuł :
Comparability study of monocyte derived dendritic cells, primary monocytes, and THP1 cells for innate immune responses.
Autorzy :
Wen Y; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, USA.
Wang X; Lilly Biotechnology Center, Eli Lilly and Company, San Diego, CA 92121, USA.
Cahya S; Lilly Biotechnology Center, Eli Lilly and Company, San Diego, CA 92121, USA.
Anderson P; Lilly Biotechnology Center, Eli Lilly and Company, San Diego, CA 92121, USA.
Velasquez C; Lilly Biotechnology Center, Eli Lilly and Company, San Diego, CA 92121, USA.
Torres C; Lilly Biotechnology Center, Eli Lilly and Company, San Diego, CA 92121, USA.
Ferrante A; Lilly Biotechnology Center, Eli Lilly and Company, San Diego, CA 92121, USA.
Kaliyaperumal A; Lilly Biotechnology Center, Eli Lilly and Company, San Diego, CA 92121, USA. Electronic address: .
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Źródło :
Journal of immunological methods [J Immunol Methods] 2021 Nov; Vol. 498, pp. 113147. Date of Electronic Publication: 2021 Sep 09.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Antibodies, Monoclonal/*pharmacology
Dendritic Cells/*drug effects
Immunity, Innate/*drug effects
Monocytes/*drug effects
Antibodies, Monoclonal, Humanized/pharmacology ; Antigen Presentation ; Automation, Laboratory ; Cytokines/metabolism ; Dendritic Cells/immunology ; Dendritic Cells/metabolism ; Endocytosis ; Flow Cytometry ; High-Throughput Screening Assays ; Humans ; Infliximab/pharmacology ; Monocytes/immunology ; Monocytes/metabolism ; THP-1 Cells
Czasopismo naukowe
Tytuł :
Pathogenesis of Coronaviruses Through Human Monocytes and Tissue Macrophages.
Autorzy :
Huang C; Medical School, The University of Sheffield, Sheffield, United Kingdom.
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Źródło :
Viral immunology [Viral Immunol] 2021 Nov; Vol. 34 (9), pp. 597-606. Date of Electronic Publication: 2021 Jul 23.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Immunity, Innate*
Coronavirus/*immunology
Coronavirus/*pathogenicity
Coronavirus Infections/*immunology
Macrophages/*virology
Monocytes/*virology
Animals ; Coronavirus/classification ; Coronavirus Infections/pathology ; Coronavirus Infections/virology ; Cytokines/blood ; Cytokines/immunology ; Humans ; Inflammation/immunology ; Inflammation/virology ; Lung/pathology ; Macrophages/immunology ; Monocytes/immunology ; Virus Replication
Czasopismo naukowe
Tytuł :
Differentiation of THP-1 monocytes to macrophages increased mitochondrial DNA copy number but did not increase expression of mitochondrial respiratory proteins or mitochondrial transcription factor A.
Autorzy :
Okamoto M; School of Bioscience and Biotechnology, Tokyo University of Technology, 1404-1 Katakura, Hachioji, Tokyo 192-0982, Japan.
Shimogishi M; School of Bioscience and Biotechnology, Tokyo University of Technology, 1404-1 Katakura, Hachioji, Tokyo 192-0982, Japan.
Nakamura A; School of Bioscience and Biotechnology, Tokyo University of Technology, 1404-1 Katakura, Hachioji, Tokyo 192-0982, Japan.
Suga Y; School of Bioscience and Biotechnology, Tokyo University of Technology, 1404-1 Katakura, Hachioji, Tokyo 192-0982, Japan.
Sugawara K; School of Bioscience and Biotechnology, Tokyo University of Technology, 1404-1 Katakura, Hachioji, Tokyo 192-0982, Japan.
Sato M; School of Agriculture, Meiji University, Kawasaki, Kanagawa 214-8571, Japan.
Nishi R; School of Bioscience and Biotechnology, Tokyo University of Technology, 1404-1 Katakura, Hachioji, Tokyo 192-0982, Japan.
Fujisawa A; School of Bioscience and Biotechnology, Tokyo University of Technology, 1404-1 Katakura, Hachioji, Tokyo 192-0982, Japan.
Yamamoto Y; School of Bioscience and Biotechnology, Tokyo University of Technology, 1404-1 Katakura, Hachioji, Tokyo 192-0982, Japan.
Kashiba M; School of Bioscience and Biotechnology, Tokyo University of Technology, 1404-1 Katakura, Hachioji, Tokyo 192-0982, Japan. Electronic address: .
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Źródło :
Archives of biochemistry and biophysics [Arch Biochem Biophys] 2021 Oct 15; Vol. 710, pp. 108988. Date of Electronic Publication: 2021 Jul 16.
Typ publikacji :
Journal Article
MeSH Terms :
DNA, Mitochondrial/*genetics
DNA, Mitochondrial/*metabolism
Macrophages/*cytology
Macrophages/*metabolism
Monocytes/*cytology
Monocytes/*metabolism
Cell Differentiation/drug effects ; Cell Differentiation/genetics ; Cell Differentiation/physiology ; DNA Copy Number Variations ; DNA-Binding Proteins/metabolism ; Humans ; Macrophages/drug effects ; Membrane Transport Proteins/metabolism ; Mitochondria/metabolism ; Mitochondria/ultrastructure ; Mitochondrial Proteins/metabolism ; Monocytes/drug effects ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Receptors, Cell Surface/metabolism ; THP-1 Cells ; Tetradecanoylphorbol Acetate/pharmacology ; Transcription Factors/metabolism ; Ubiquinone/analogs & derivatives ; Ubiquinone/metabolism
Czasopismo naukowe
Tytuł :
A TLR5 mono-agonist restores inhibited immune responses to Streptococcus pneumoniae during influenza virus infection in human monocytes.
Autorzy :
Maguire PT; Viral Immunology Laboratory, School of Nursing, Psychotherapy and Community Health, Dublin City University, Dublin, Ireland.
Loughran ST; Department of Applied Science, Dundalk Institute of Technology, County Louth, Ireland.
Harvey R; National Institute for Biological Standards and Controls, Potters Bar, Herts, United Kingdom.
Johnson PA; Viral Immunology Laboratory, School of Nursing, Psychotherapy and Community Health, Dublin City University, Dublin, Ireland.
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Źródło :
PloS one [PLoS One] 2021 Oct 13; Vol. 16 (10), pp. e0258261. Date of Electronic Publication: 2021 Oct 13 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Immunity*/drug effects
Influenza, Human/*immunology
Influenza, Human/*virology
Monocytes/*immunology
Monocytes/*virology
Streptococcus pneumoniae/*immunology
Toll-Like Receptor 5/*agonists
Humans ; Influenza A virus/drug effects ; Influenza A virus/immunology ; Monocytes/drug effects ; Nuclear Receptor Subfamily 1, Group F, Member 3/metabolism ; Reproducibility of Results ; Signal Transduction/drug effects ; Streptococcus pneumoniae/drug effects ; Toll-Like Receptor 2/metabolism ; Toll-Like Receptor 4/metabolism ; Transforming Growth Factor beta/pharmacology
Czasopismo naukowe
Tytuł :
Dynamic alterations in monocyte numbers, subset frequencies and activation markers in acute and convalescent COVID-19 individuals.
Autorzy :
Rajamanickam A; International Center for Excellence in Research - ICMR- National Institute for Research in Tuberculosis, Chennai, TamilNadu, India. .
Kumar NP; Immunology-ICMR-National Institute for Research in Tuberculosis, Chennai, TamilNadu, India.
Pandiarajan AN; International Center for Excellence in Research - ICMR- National Institute for Research in Tuberculosis, Chennai, TamilNadu, India.
Selvaraj N; International Center for Excellence in Research - ICMR- National Institute for Research in Tuberculosis, Chennai, TamilNadu, India.
Munisankar S; International Center for Excellence in Research - ICMR- National Institute for Research in Tuberculosis, Chennai, TamilNadu, India.
Renji RM; International Center for Excellence in Research - ICMR- National Institute for Research in Tuberculosis, Chennai, TamilNadu, India.
Venkatramani V; International Center for Excellence in Research - ICMR- National Institute for Research in Tuberculosis, Chennai, TamilNadu, India.
Murhekar M; ICMR-National Institute of Epidemiology, Chennai, TamilNadu, India.
Thangaraj JWV; ICMR-National Institute of Epidemiology, Chennai, TamilNadu, India.
Kumar MS; ICMR-National Institute of Epidemiology, Chennai, TamilNadu, India.
Kumar CPG; ICMR-National Institute of Epidemiology, Chennai, TamilNadu, India.
Bhatnagar T; ICMR-National Institute of Epidemiology, Chennai, TamilNadu, India.
Ponnaiah M; ICMR-National Institute of Epidemiology, Chennai, TamilNadu, India.
Sabarinathan R; ICMR-National Institute of Epidemiology, Chennai, TamilNadu, India.
Saravanakumar V; ICMR-National Institute of Epidemiology, Chennai, TamilNadu, India.
Babu S; International Center for Excellence in Research - ICMR- National Institute for Research in Tuberculosis, Chennai, TamilNadu, India.
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Źródło :
Scientific reports [Sci Rep] 2021 Oct 12; Vol. 11 (1), pp. 20254. Date of Electronic Publication: 2021 Oct 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Monocytes*/cytology
Monocytes*/immunology
COVID-19/*immunology
Acute Disease ; Adolescent ; Adult ; Aged ; Biomarkers/blood ; Convalescence ; Female ; Humans ; Leukocyte Count ; Male ; Middle Aged ; Young Adult
Czasopismo naukowe
Tytuł :
Applicability of different cell line-derived dendritic cell-like cells in autophagy research.
Autorzy :
Prins MMC; Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands; Department of Gastroenterology and Hepatology, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands. Electronic address: .
van Roest M; Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands. Electronic address: .
Vermeulen JLM; Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands. Electronic address: .
Tjabringa GS; Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands. Electronic address: .
van de Graaf SFJ; Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands; Department of Gastroenterology and Hepatology, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands. Electronic address: .
Koelink PJ; Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands; Department of Gastroenterology and Hepatology, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands. Electronic address: .
Wildenberg ME; Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands; Department of Gastroenterology and Hepatology, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands. Electronic address: .
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Źródło :
Journal of immunological methods [J Immunol Methods] 2021 Oct; Vol. 497, pp. 113106. Date of Electronic Publication: 2021 Jul 26.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Cell Differentiation*
Adenine/*analogs & derivatives
Autophagy/*drug effects
Dendritic Cells/*drug effects
Macrolides/*pharmacology
Monocytes/*immunology
Sirolimus/*pharmacology
Adenine/pharmacology ; Autophagy/genetics ; Autophagy-Related Proteins/genetics ; Autophagy-Related Proteins/metabolism ; Cytokines/metabolism ; Dendritic Cells/immunology ; Dendritic Cells/metabolism ; Dendritic Cells/pathology ; Flow Cytometry ; Genotype ; HL-60 Cells ; Humans ; Microscopy, Fluorescence ; Monocytes/metabolism ; Monocytes/pathology ; Phenotype ; Polymorphism, Single Nucleotide ; THP-1 Cells ; U937 Cells
Czasopismo naukowe
Tytuł :
Distribution of monocytes subpopulations in the peripheral blood from patients with Behçet's disease - Impact of disease status and colchicine use.
Autorzy :
Gazzito Del Padre TC; Rheumatology Division, Department of Medicine, Universidade Federal de São Paulo - Escola Paulista de Medicina, Rua Botucatu, 740, 04023-900 São Paulo, SP, Brazil.
Belem JMFM; Rheumatology Division, Department of Medicine, Universidade Federal de São Paulo - Escola Paulista de Medicina, Rua Botucatu, 740, 04023-900 São Paulo, SP, Brazil.
de Aguiar MF; Rheumatology Division, Department of Medicine, Universidade Federal de São Paulo - Escola Paulista de Medicina, Rua Botucatu, 740, 04023-900 São Paulo, SP, Brazil.
Torquato HFV; Department of Biochemistry, Universidade Federal de São Paulo - Escola Paulista de Medicina, Rua Três de Maio, 100 fifth floor, São Paulo-SP 04023-900, SP, Brazil; Faculdade de Farmácia, Centro Universitário Braz Cubas, Avenida Francisco Rodrigues Filho, 1233, Mogi das Cruzes, SP 08773-380, Brazil.
Paredes-Gamero EJ; Department of Biochemistry, Universidade Federal de São Paulo - Escola Paulista de Medicina, Rua Três de Maio, 100 fifth floor, São Paulo-SP 04023-900, SP, Brazil; Faculdade de Ciências Farmacêuticas, Alimentos e Nutrição - Universidade Federal de Mato Grosso do Sul, Campo Grande, MS 79070-900, Brazil. Electronic address: .
Abdulahad WH; Department of Rheumatology and Clinical Immunology, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, the Netherlands. Electronic address: .
Brouwer E; Department of Rheumatology and Clinical Immunology, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, the Netherlands. Electronic address: .
de Souza AWS; Rheumatology Division, Department of Medicine, Universidade Federal de São Paulo - Escola Paulista de Medicina, Rua Botucatu, 740, 04023-900 São Paulo, SP, Brazil. Electronic address: .
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Źródło :
Clinical immunology (Orlando, Fla.) [Clin Immunol] 2021 Oct; Vol. 231, pp. 108854. Date of Electronic Publication: 2021 Sep 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Behcet Syndrome/*immunology
Colchicine/*therapeutic use
Monocytes/*immunology
Tubulin Modulators/*therapeutic use
Adult ; Behcet Syndrome/drug therapy ; Cross-Sectional Studies ; Female ; Humans ; Male ; Middle Aged ; Monocytes/drug effects
Czasopismo naukowe
Tytuł :
Selective depletion of a CD64-expressing phagocyte subset mediates protection against toxic kidney injury and failure.
Autorzy :
Salei N; Walter-Brendel-Centre of Experimental Medicine, University Hospital, Ludwig-Maximilians-Universität in Munich, 82152 Planegg-Martinsried, Germany.; Biomedical Center, Institute for Cardiovascular Physiology and Pathophysiology, Faculty of Medicine, Ludwig-Maximilians-Universität in Munich, 82152 Planegg-Martinsried, Germany.
Ji X; Walter-Brendel-Centre of Experimental Medicine, University Hospital, Ludwig-Maximilians-Universität in Munich, 82152 Planegg-Martinsried, Germany.; Biomedical Center, Institute for Cardiovascular Physiology and Pathophysiology, Faculty of Medicine, Ludwig-Maximilians-Universität in Munich, 82152 Planegg-Martinsried, Germany.
Pakalniškytė D; Walter-Brendel-Centre of Experimental Medicine, University Hospital, Ludwig-Maximilians-Universität in Munich, 82152 Planegg-Martinsried, Germany.; Biomedical Center, Institute for Cardiovascular Physiology and Pathophysiology, Faculty of Medicine, Ludwig-Maximilians-Universität in Munich, 82152 Planegg-Martinsried, Germany.
Kuentzel V; Walter-Brendel-Centre of Experimental Medicine, University Hospital, Ludwig-Maximilians-Universität in Munich, 82152 Planegg-Martinsried, Germany.; Biomedical Center, Institute for Cardiovascular Physiology and Pathophysiology, Faculty of Medicine, Ludwig-Maximilians-Universität in Munich, 82152 Planegg-Martinsried, Germany.
Rambichler S; Walter-Brendel-Centre of Experimental Medicine, University Hospital, Ludwig-Maximilians-Universität in Munich, 82152 Planegg-Martinsried, Germany.; Biomedical Center, Institute for Cardiovascular Physiology and Pathophysiology, Faculty of Medicine, Ludwig-Maximilians-Universität in Munich, 82152 Planegg-Martinsried, Germany.
Li N; Division of Nephrology, The Seventh Affiliated Hospital, Sun Yat-sen University, 518107 Shenzhen, China.; Division of Nephrology, Medizinische Klinik und Poliklinik IV, University Hospital, Ludwig-Maximilians-Universität in Munich, 80366 Munich, Germany.
Moser M; Institute of Experimental Hematology, School of Medicine, Technische Universität München, D-81675 Munich, Germany.
Steiger K; Institute of Pathology, School of Medicine, Technische Universität München, D-81675 München, Germany.
Buch T; Institute of Laboratory Animal Science, University of Zürich, 8956 Zürich, Switzerland.
Anders HJ; Division of Nephrology, Medizinische Klinik und Poliklinik IV, University Hospital, Ludwig-Maximilians-Universität in Munich, 80366 Munich, Germany.
Schraml BU; Walter-Brendel-Centre of Experimental Medicine, University Hospital, Ludwig-Maximilians-Universität in Munich, 82152 Planegg-Martinsried, Germany; .; Biomedical Center, Institute for Cardiovascular Physiology and Pathophysiology, Faculty of Medicine, Ludwig-Maximilians-Universität in Munich, 82152 Planegg-Martinsried, Germany.
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2021 Sep 28; Vol. 118 (39).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Acute Kidney Injury/*prevention & control
Dendritic Cells/*immunology
Heparin-binding EGF-like Growth Factor/*metabolism
Macrophages/*immunology
Monocytes/*immunology
Phagocytes/*metabolism
Acute Kidney Injury/chemically induced ; Acute Kidney Injury/metabolism ; Acute Kidney Injury/pathology ; Animals ; Antineoplastic Agents/toxicity ; Cisplatin/toxicity ; Dendritic Cells/metabolism ; Dendritic Cells/pathology ; Female ; Macrophages/metabolism ; Macrophages/pathology ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Monocytes/metabolism ; Monocytes/pathology ; Phagocytes/cytology ; Receptors, IgG
Czasopismo naukowe
Tytuł :
Effect of ORF7 of SARS-CoV-2 on the Chemotaxis of Monocytes and Neutrophils In Vitro.
Autorzy :
Wang G; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Guan J; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Li G; Department of Liver Diseases, National Clinical Research Center for Infectious Disease, Shenzhen Third People's Hospital, The Second Affiliated Hospital, School of Medicine, Southern University of Science and Technology, Shenzhen, 518000 Guangdong, China.
Wu F; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Yang Q; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Huang C; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Shao J; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Xu L; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Guo Z; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Zhou Q; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Zhu H; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Chen Z; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
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Źródło :
Disease markers [Dis Markers] 2021 Sep 28; Vol. 2021, pp. 6803510. Date of Electronic Publication: 2021 Sep 28 (Print Publication: 2021).
Typ publikacji :
Journal Article
MeSH Terms :
Chemotaxis*
COVID-19/*metabolism
Monocytes/*pathology
Neutrophils/*pathology
Open Reading Frames/*physiology
Pneumonia/*pathology
Viral Proteins/*metabolism
A549 Cells ; Chemokine CCL2/metabolism ; Humans ; In Vitro Techniques ; Monocytes/immunology ; Monocytes/metabolism ; Neutrophils/immunology ; Neutrophils/metabolism ; Pneumonia/immunology ; Pneumonia/metabolism ; SARS-CoV-2/metabolism ; Viral Proteins/genetics
Czasopismo naukowe
Tytuł :
Monocyte transcriptomes from patients with axial spondyloarthritis reveal dysregulated monocytopoiesis and a distinct inflammatory imprint.
Autorzy :
Karow F; Medizinische Klinik für Gastroenterologie, Infektiologie und Rheumatologie, Campus Benjamin Franklin, Charité-Universitätsmedizin Berlin, Hindenburgdamm 30, 12200, Berlin, Germany.
Smiljanovic B; Medizinische Klinik für Rheumatologie und Klinische Immunologie, Campus Mitte, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Grün JR; Deutsches Rheumaforschungszentrum (DRFZ), A Leibniz Institute, Berlin, Germany.
Poddubnyy D; Medizinische Klinik für Gastroenterologie, Infektiologie und Rheumatologie, Campus Benjamin Franklin, Charité-Universitätsmedizin Berlin, Hindenburgdamm 30, 12200, Berlin, Germany.
Proft F; Medizinische Klinik für Gastroenterologie, Infektiologie und Rheumatologie, Campus Benjamin Franklin, Charité-Universitätsmedizin Berlin, Hindenburgdamm 30, 12200, Berlin, Germany.
Talpin A; Infection & Inflammation, UMR 1173, Inserm, UVSQ/Université Paris Saclay, Montigny-le-Bretonneux, France.; Laboratoire d'Excellence Inflamex, Universite de Paris, Paris, France.
Hue C; Infection & Inflammation, UMR 1173, Inserm, UVSQ/Université Paris Saclay, Montigny-le-Bretonneux, France.; Laboratoire d'Excellence Inflamex, Universite de Paris, Paris, France.
Boland A; Infection & Inflammation, UMR 1173, Inserm, UVSQ/Université Paris Saclay, Montigny-le-Bretonneux, France.; CEA, Centre National de Recherche en Génomique Humaine, Université Paris-Saclay, Evry, France.
Deleuze JF; Infection & Inflammation, UMR 1173, Inserm, UVSQ/Université Paris Saclay, Montigny-le-Bretonneux, France.; CEA, Centre National de Recherche en Génomique Humaine, Université Paris-Saclay, Evry, France.
Garchon HJ; Infection & Inflammation, UMR 1173, Inserm, UVSQ/Université Paris Saclay, Montigny-le-Bretonneux, France.; Laboratoire d'Excellence Inflamex, Universite de Paris, Paris, France.; Service de Biochimie, Hôpital Ambroise Paré, Boulogne-Billancourt, France.
Ergenç I; VIB Center for Inflammation Research, Ghent University Hospital, Ghent, Belgium.; Department of Rheumatology, Ghent University, Ghent, Belgium.
De Craemer AS; VIB Center for Inflammation Research, Ghent University Hospital, Ghent, Belgium.; Department of Rheumatology, Ghent University, Ghent, Belgium.
Erben U; Medizinische Klinik für Gastroenterologie, Infektiologie und Rheumatologie, Campus Benjamin Franklin, Charité-Universitätsmedizin Berlin, Hindenburgdamm 30, 12200, Berlin, Germany.
Häupl T; Medizinische Klinik für Rheumatologie und Klinische Immunologie, Campus Mitte, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Elewaut D; VIB Center for Inflammation Research, Ghent University Hospital, Ghent, Belgium.; Department of Rheumatology, Ghent University, Ghent, Belgium.
Breban M; Infection & Inflammation, UMR 1173, Inserm, UVSQ/Université Paris Saclay, Montigny-le-Bretonneux, France.; Laboratoire d'Excellence Inflamex, Universite de Paris, Paris, France.; Service de Rhumatologie, Hôpital Ambroise Paré, Boulogne-Billancourt, France.
Grützkau A; Deutsches Rheumaforschungszentrum (DRFZ), A Leibniz Institute, Berlin, Germany.
Syrbe U; Medizinische Klinik für Gastroenterologie, Infektiologie und Rheumatologie, Campus Benjamin Franklin, Charité-Universitätsmedizin Berlin, Hindenburgdamm 30, 12200, Berlin, Germany. .
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Źródło :
Arthritis research & therapy [Arthritis Res Ther] 2021 Sep 24; Vol. 23 (1), pp. 246. Date of Electronic Publication: 2021 Sep 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Monocytes*
Spondylarthritis*/genetics
Cytokines ; Gene Expression Profiling ; Humans ; Transcriptome
Czasopismo naukowe
Tytuł :
Monocyte-derived transcriptome signature indicates antibody-dependent cellular phagocytosis as a potential mechanism of vaccine-induced protection against HIV-1.
Autorzy :
Shangguan S; US Military HIV Research Program (MHRP), Walter Reed Army Institute of Research, Silver Spring, United States.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, United States.
Ehrenberg PK; US Military HIV Research Program (MHRP), Walter Reed Army Institute of Research, Silver Spring, United States.
Geretz A; US Military HIV Research Program (MHRP), Walter Reed Army Institute of Research, Silver Spring, United States.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, United States.
Yum L; US Military HIV Research Program (MHRP), Walter Reed Army Institute of Research, Silver Spring, United States.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, United States.
Kundu G; US Military HIV Research Program (MHRP), Walter Reed Army Institute of Research, Silver Spring, United States.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, United States.
May K; US Military HIV Research Program (MHRP), Walter Reed Army Institute of Research, Silver Spring, United States.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, United States.
Fourati S; Department of Pathology and Laboratory Medicine, Emory University, Atlanta, United States.
Nganou-Makamdop K; Vaccine Research Center, NIH, Bethesda, United States.
Williams LD; Departments of Surgery, Immunology and Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, United States.
Sawant S; Departments of Surgery, Immunology and Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, United States.
Lewitus E; US Military HIV Research Program (MHRP), Walter Reed Army Institute of Research, Silver Spring, United States.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, United States.
Pitisuttithum P; Vaccine Trial Centre, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Nitayaphan S; Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand.
Chariyalertsak S; Research Institute for Health Sciences and Faculty of Public Health, Chiang Mai University, Chiang Mai, Thailand.
Rerks-Ngarm S; Department of Disease Control, Ministry of Public Health, Nonthaburi, Thailand.
Rolland M; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, United States.
Douek DC; Vaccine Research Center, NIH, Bethesda, United States.
Gilbert P; Fred Hutchinson Cancer Research Center, Seattle, United States.
Tomaras GD; Departments of Surgery, Immunology and Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, United States.
Michael NL; US Military HIV Research Program (MHRP), Walter Reed Army Institute of Research, Silver Spring, United States.
Vasan S; US Military HIV Research Program (MHRP), Walter Reed Army Institute of Research, Silver Spring, United States.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, United States.
Thomas R; US Military HIV Research Program (MHRP), Walter Reed Army Institute of Research, Silver Spring, United States.
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Źródło :
ELife [Elife] 2021 Sep 17; Vol. 10. Date of Electronic Publication: 2021 Sep 17.
Typ publikacji :
Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Gene Expression Profiling*
Transcriptome*
AIDS Vaccines/*therapeutic use
HIV Antibodies/*immunology
HIV Infections/*prevention & control
HIV-1/*immunology
Monocytes/*drug effects
Phagocytosis/*drug effects
Vaccines, DNA/*therapeutic use
AIDS Vaccines/adverse effects ; Clinical Trials as Topic ; Databases, Genetic ; HIV Infections/genetics ; HIV Infections/immunology ; HIV Infections/virology ; HIV-1/pathogenicity ; Host-Pathogen Interactions ; Humans ; Immunogenicity, Vaccine ; Monocytes/immunology ; Monocytes/metabolism ; Oligonucleotide Array Sequence Analysis ; RNA-Seq ; Single-Cell Analysis ; Time Factors ; Treatment Outcome ; Vaccination ; Vaccines, DNA/adverse effects
Czasopismo naukowe
Tytuł :
Single-cell RNA sequencing of peripheral blood mononuclear cells from acute Kawasaki disease patients.
Autorzy :
Wang Z; Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China. .
Xie L; Department of Cardiology, Shanghai Children's Hospital, Shanghai Jiaotong University, Shanghai, China.
Ding G; Institute for Digital Health, International Human Phenome Institutes (Shanghai), Shanghai, China.; Gui'an Bio-Med Big Data Center, Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences, Guiyang, China.
Song S; Department of Cardiology, Shanghai Children's Hospital, Shanghai Jiaotong University, Shanghai, China.
Chen L; Department of Cardiology, Shanghai Children's Hospital, Shanghai Jiaotong University, Shanghai, China.
Li G; Shanghai QianBei Med. Technology Co. Ltd, Shanghai, China.
Xia M; Department of Clinical Laboratory, Shanghai Children's Hospital, Shanghai Jiaotong University, Shanghai, China.
Han D; Department of Clinical Laboratory, Shanghai Children's Hospital, Shanghai Jiaotong University, Shanghai, China.
Zheng Y; Department of Clinical Laboratory, Shanghai Children's Hospital, Shanghai Jiaotong University, Shanghai, China.
Liu J; Shanghai QianBei Med. Technology Co. Ltd, Shanghai, China.
Xiao T; Department of Cardiology, Shanghai Children's Hospital, Shanghai Jiaotong University, Shanghai, China.
Zhang H; Department of Clinical Laboratory, Shanghai Children's Hospital, Shanghai Jiaotong University, Shanghai, China.
Huang Y; Department of Cardiology, Shanghai Children's Hospital, Shanghai Jiaotong University, Shanghai, China.
Li Y; Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou, China. .; Bio-Med Big Data Center, Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences, Shanghai, China. .; Collaborative Innovation Center for Genetics and Development, Fudan University, Shanghai, China. .; Guangzhou Laboratory, Guangzhou, China. .
Huang M; Department of Cardiology, Shanghai Children's Hospital, Shanghai Jiaotong University, Shanghai, China. .
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Źródło :
Nature communications [Nat Commun] 2021 Sep 14; Vol. 12 (1), pp. 5444. Date of Electronic Publication: 2021 Sep 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
B-Lymphocytes/*immunology
CD8-Positive T-Lymphocytes/*immunology
Monocytes/*immunology
Mucocutaneous Lymph Node Syndrome/*genetics
Plasma Cells/*immunology
Acute Disease ; Adaptive Immunity/drug effects ; B-Lymphocytes/drug effects ; B-Lymphocytes/pathology ; CD8-Positive T-Lymphocytes/drug effects ; CD8-Positive T-Lymphocytes/pathology ; Case-Control Studies ; Cell Proliferation ; Child ; Child, Preschool ; Clone Cells ; Female ; Gene Expression ; Humans ; Immunity, Innate/drug effects ; Immunoglobulins, Intravenous/therapeutic use ; Immunophenotyping ; Male ; Monocytes/drug effects ; Monocytes/pathology ; Mucocutaneous Lymph Node Syndrome/drug therapy ; Mucocutaneous Lymph Node Syndrome/immunology ; Mucocutaneous Lymph Node Syndrome/pathology ; Plasma Cells/drug effects ; Plasma Cells/pathology ; Receptors, Antigen, B-Cell/genetics ; Receptors, Antigen, B-Cell/immunology ; Receptors, Antigen, T-Cell/genetics ; Receptors, Antigen, T-Cell/immunology ; Sequence Analysis, RNA ; Single-Cell Analysis
Czasopismo naukowe
Tytuł :
Differential Expression of Human MicroRNAs During Dengue Virus Infection in THP-1 Monocytes.
Autorzy :
Rossi ÁD; Laboratório de Virologia Molecular, Departamento de Genética, Instituto de Biologia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Higa LM; Laboratório de Virologia Molecular, Departamento de Genética, Instituto de Biologia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.; Laboratório de Bioquímica de Vírus, Instituto de Bioquímica Médica Leopoldo de Meis, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Herlinger AL; Laboratório de Virologia Molecular, Departamento de Genética, Instituto de Biologia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Ribeiro-Alves M; Laboratório de Pesquisa Clínica em DST/AIDS, Instituto Nacional de Infectologia Evandro Chagas, FIOCRUZ, Rio de Janeiro, Brazil.
de Menezes MT; Laboratório de Virologia Molecular, Departamento de Genética, Instituto de Biologia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Giannini ALM; Laboratório de Genômica Funcional e Transdução de Sinal, Departamento de Genética, Instituto de Biologia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Cardoso CC; Laboratório de Virologia Molecular, Departamento de Genética, Instituto de Biologia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Da Poian AT; Laboratório de Bioquímica de Vírus, Instituto de Bioquímica Médica Leopoldo de Meis, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Tanuri A; Laboratório de Virologia Molecular, Departamento de Genética, Instituto de Biologia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Aguiar RS; Laboratório de Virologia Molecular, Departamento de Genética, Instituto de Biologia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.; Laboratório de Biologia Integrativa, Departamento de Genética, Ecologia e Evolução, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
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Źródło :
Frontiers in cellular and infection microbiology [Front Cell Infect Microbiol] 2021 Sep 08; Vol. 11, pp. 714088. Date of Electronic Publication: 2021 Sep 08 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Dengue*/genetics
MicroRNAs*/genetics
Monocytes*/metabolism
Monocytes*/virology
Dengue Virus ; Humans ; Immunity, Innate ; THP-1 Cells
Czasopismo naukowe
Tytuł :
Progress and challenge for computational quantification of tissue immune cells.
Autorzy :
Chen Z; Suzhou Institute of Systems Medicine, Center for Systems Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Jiangsu, Suzhou, China.
Wu A; Suzhou Institute of Systems Medicine, Center for Systems Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Jiangsu, Suzhou, China.
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Źródło :
Briefings in bioinformatics [Brief Bioinform] 2021 Sep 02; Vol. 22 (5).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Immune System*
Models, Immunological*
Lymphocytes/*immunology
Monocytes/*immunology
Neoplasm Proteins/*genetics
Neoplasms/*immunology
Animals ; Computer Simulation ; Fibroblasts/classification ; Fibroblasts/immunology ; Fibroblasts/pathology ; Gene Expression Regulation, Neoplastic ; Humans ; Lymphocytes/classification ; Lymphocytes/pathology ; Mice ; MicroRNAs/genetics ; MicroRNAs/immunology ; Monocytes/classification ; Monocytes/pathology ; Neoplasm Proteins/immunology ; Neoplasms/genetics ; Neoplasms/pathology ; RNA, Messenger/genetics ; RNA, Messenger/immunology ; Signal Transduction
Czasopismo naukowe
Tytuł :
The receptor of the colony-stimulating factor-1 (CSF-1R) is a novel prognostic factor and therapeutic target in follicular lymphoma.
Autorzy :
Valero JG; Department of Hematology-Oncology, IDIBAPS, Barcelona, Spain.; Centro de Investigación Biomédica en Red-Oncología (CIBERONC), Madrid, Spain.
Matas-Céspedes A; Department of Hematology-Oncology, IDIBAPS, Barcelona, Spain.; Centro de Investigación Biomédica en Red-Oncología (CIBERONC), Madrid, Spain.; Clinical Pharmacology and Safety Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK.
Arenas F; Department of Hematology-Oncology, IDIBAPS, Barcelona, Spain.; Centro de Investigación Biomédica en Red-Oncología (CIBERONC), Madrid, Spain.
Rodriguez V; Department of Hematology-Oncology, IDIBAPS, Barcelona, Spain.; Garvan Institute of Medical Research, Sydney, Australia.
Carreras J; Department of Pathology, Tokai University, School of Medicine, Isehara, Kanagawa, Japan.
Serrat N; Department of Hematology-Oncology, IDIBAPS, Barcelona, Spain.
Guerrero-Hernández M; Department of Hematology-Oncology, IDIBAPS, Barcelona, Spain.; Department of Gene Regulation, Stem Cells and Cancer Center for Genomic Regulation (CRG-PRBB), Barcelona, Spain.
Yahiaoui A; Gilead Sciences, Inc, Foster City, USA.
Balagué O; Hematopathology Unit, Pathology Department, Hospital Clínic-IDIBAPS, Barcelona, Spain.
Martin S; Department of Hematology-Oncology, IDIBAPS, Barcelona, Spain.; Centro de Investigación Biomédica en Red-Oncología (CIBERONC), Madrid, Spain.
Capdevila C; Department of Hematology-Oncology, IDIBAPS, Barcelona, Spain.
Hernández L; Department of Hematology-Oncology, IDIBAPS, Barcelona, Spain.; Centro de Investigación Biomédica en Red-Oncología (CIBERONC), Madrid, Spain.
Magnano L; Department of Hematology-Oncology, IDIBAPS, Barcelona, Spain.; Department of Hematology, Hospital Clinic -IDIBAPS, Barcelona, Spain.
Rivas-Delgado A; Department of Hematology-Oncology, IDIBAPS, Barcelona, Spain.; Department of Hematology, Hospital Clinic -IDIBAPS, Barcelona, Spain.
Tannheimer S; Gilead Sciences, Inc, Foster City, USA.
Cid MC; Department of Autoimmune Diseases, Hospital Clinic, University of Barcelona, IDIBAPS, Barcelona, Spain.
Campo E; Department of Hematology-Oncology, IDIBAPS, Barcelona, Spain.; Centro de Investigación Biomédica en Red-Oncología (CIBERONC), Madrid, Spain.; Hematopathology Unit, Pathology Department, Hospital Clínic-IDIBAPS, Barcelona, Spain.; University of Barcelona, Medical School, Barcelona, Spain.
López-Guillermo A; Department of Hematology-Oncology, IDIBAPS, Barcelona, Spain.; Centro de Investigación Biomédica en Red-Oncología (CIBERONC), Madrid, Spain.; Department of Hematology, Hospital Clinic -IDIBAPS, Barcelona, Spain.; University of Barcelona, Medical School, Barcelona, Spain.
Colomer D; Department of Hematology-Oncology, IDIBAPS, Barcelona, Spain.; Centro de Investigación Biomédica en Red-Oncología (CIBERONC), Madrid, Spain.; Hematopathology Unit, Pathology Department, Hospital Clínic-IDIBAPS, Barcelona, Spain.; University of Barcelona, Medical School, Barcelona, Spain.
Pérez-Galán P; Department of Hematology-Oncology, IDIBAPS, Barcelona, Spain. .; Centro de Investigación Biomédica en Red-Oncología (CIBERONC), Madrid, Spain. .
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Źródło :
Leukemia [Leukemia] 2021 Sep; Vol. 35 (9), pp. 2635-2649. Date of Electronic Publication: 2021 Mar 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation, Neoplastic*
Tumor Microenvironment*
Biomarkers, Tumor/*metabolism
Lymphoma, Follicular/*pathology
Macrophages/*pathology
Monocytes/*pathology
Receptor, Macrophage Colony-Stimulating Factor/*metabolism
Aminopyridines/pharmacology ; Animals ; Apoptosis ; Biomarkers, Tumor/genetics ; Cell Differentiation ; Cell Proliferation ; Humans ; Lymphoma, Follicular/drug therapy ; Lymphoma, Follicular/metabolism ; Macrophages/drug effects ; Macrophages/metabolism ; Mice ; Monocytes/drug effects ; Monocytes/metabolism ; Phosphorylation ; Pyrroles/pharmacology ; Receptor, Macrophage Colony-Stimulating Factor/antagonists & inhibitors ; Receptor, Macrophage Colony-Stimulating Factor/genetics ; Tumor Cells, Cultured ; Xenograft Model Antitumor Assays
Czasopismo naukowe

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