Autor: "Morris, Andrew P." - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Genome-Wide Gene-Set Analysis Identifies Molecular Mechanisms Associated with ALS.
Autorzy:: Vasilopoulou C; Personalised Medicine Centre, School of Medicine, Ulster University, Londonderry BT47 6SB, UK.
McDaid-McCloskey SL; Personalised Medicine Centre, School of Medicine, Ulster University, Londonderry BT47 6SB, UK.
McCluskey G; Personalised Medicine Centre, School of Medicine, Ulster University, Londonderry BT47 6SB, UK.
Duguez S; Personalised Medicine Centre, School of Medicine, Ulster University, Londonderry BT47 6SB, UK.
Morris AP; Centre for Genetics and Genomics Versus Arthritis, Centre for Musculoskeletal Research, University of Manchester, Manchester M13 9PT, UK.
Duddy W; Personalised Medicine Centre, School of Medicine, Ulster University, Londonderry BT47 6SB, UK.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Feb 16; Vol. 24 (4). Date of Electronic Publication: 2023 Feb 16.
Typ publikacji:: Meta-Analysis; Journal Article
MeSH Terms:: Amyotrophic Lateral Sclerosis*/genetics
Humans ; Genome-Wide Association Study ; Genotype ; Motor Neurons

Czasopismo naukowe

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Skocz do pozycji: 2.

Tytuł:: Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals.
Autorzy:: Winkler TW; Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany. .
Rasheed H; K. G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.; MRC Integrative Epidemiology Unit, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.; Division of Medicine and Laboratory Sciences, University of Oslo, Oslo, Norway.
Teumer A; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.; DZHK (German Center for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.; Department of Population Medicine and Lifestyle Diseases Prevention, Medical University of Bialystok, Bialystok, Poland.
Gorski M; Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany.; Department of Nephrology, University Hospital Regensburg, Regensburg, Germany.
Rowan BX; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, USA.; Department of Veteran's Affairs, Tennessee Valley Healthcare System (626)/Vanderbilt University, Nashville, TN, USA.
Stanzick KJ; Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany.
Thomas LF; K. G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Clinical and Molecular Medicine, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.; BioCore-Bioinformatics Core Facility, Norwegian University of Science and Technology, Trondheim, Norway.
Tin A; Department of Medicine, University of Mississippi Medical Center, Jackson, MS, USA.; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Hoppmann A; Institute of Genetic Epidemiology, Department of Data Driven Medicine, Faculty of Medicine and Medical Center-University of Freiburg, Freiburg, Germany.
Chu AY; Genetics, Merck & Co., Inc, Kenilworth, NJ, USA.
Tayo B; Department of Public Health Sciences, Loyola University Chicago, Maywood, IL, USA.
Thio CHL; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Cusi D; Institute of Biomedical Technologies, National Research Council of Italy, Milan, Italy.; Bio4Dreams-Business Nursery for Life Sciences, Milan, Italy.
Chai JF; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore.
Sieber KB; Target Sciences-Genetics, GlaxoSmithKline, Collegeville, PA, USA.
Horn K; Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany.; LIFE Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany.
Li M; Division of Nephrology and Hypertension, Department of Medicine, University of Utah, Salt Lake City, UT, USA.
Scholz M; Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany.; LIFE Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany.
Cocca M; Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo', Trieste, Italy.
Wuttke M; Institute of Genetic Epidemiology, Department of Data Driven Medicine, Faculty of Medicine and Medical Center-University of Freiburg, Freiburg, Germany.; Renal Division, Department of Medicine IV, Faculty of Medicine and Medical Center-University of Freiburg, Freiburg, Germany.
van der Most PJ; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Yang Q; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.
Ghasemi S; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.; DZHK (German Center for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.; Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany.
Nutile T; Institute of Genetics and Biophysics 'Adriano Buzzati-Traverso'-CNR, Naples, Italy.
Li Y; Institute of Genetic Epidemiology, Department of Data Driven Medicine, Faculty of Medicine and Medical Center-University of Freiburg, Freiburg, Germany.
Pontali G; Eurac Research, Institute for Biomedicine (affiliated with the University of Lübeck), Bolzano, Italy.; University of Trento, Department of Cellular, Computational and Integrative Biology-CIBIO, Trento, Italy.
Günther F; Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany.; Statistical Consulting Unit StaBLab, Department of Statistics, LMU Munich, Munich, Germany.
Dehghan A; MRC Centre for Environment and Health, Department of Epidemiology and Biostatistics, School of Public Health, Faculty of Medicine, Imperial College London, London, UK.; Dementia Research Institute, Imperial College London, London, UK.
Correa A; Department of Medicine, University of Mississippi Medical Center, Jackson, MS, USA.
Parsa A; Division of Kidney, Urologic and Hematologic Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA.; University of Maryland School of Medicine, Baltimore, MD, USA.
Feresin A; Department of Medicine, Surgery and Health Sciences, University of Trieste, Trieste, Italy.
de Vries APJ; Section of Nephrology, Department of Internal Medicine, Leiden University Medical Center, Leiden, The Netherlands.
Zonderman AB; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Intramural Research Program, US National Institutes of Health, Baltimore, MD, USA.
Smith AV; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland.; CNRS UMR 8199, European Genomic Institute for Diabetes (EGID), Institut Pasteur de Lille, University of Lille, Lille, France.
Oldehinkel AJ; Interdisciplinary Center of Psychopathology and Emotion Regulation (ICPE), University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
De Grandi A; Eurac Research, Institute for Biomedicine (affiliated with the University of Lübeck), Bolzano, Italy.
Rosenkranz AR; Department of Internal Medicine, Division of Nephrology, Medical University Graz, Graz, Austria.
Franke A; Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel, Germany.
Teren A; LIFE Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany.; Heart Center Leipzig, Leipzig, Germany.
Metspalu A; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia.
Hicks AA; Eurac Research, Institute for Biomedicine (affiliated with the University of Lübeck), Bolzano, Italy.
Morris AP; Department of Health Data Science, University of Liverpool, Liverpool, UK.; Wellcome Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK.; Centre for Genetics and Genomics Versus Arthritis, Centre for Musculoskeletal Research, The University of Manchester, Manchester, UK.
Tönjes A; Medical Department III-Endocrinology, Nephrology, Rheumatology, University of Leipzig Medical Center, Leipzig, Germany.
Morgan A; Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo', Trieste, Italy.
Podgornaia AI; Genetics, Merck & Co., Inc, Kenilworth, NJ, USA.
Peters A; Institute of Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany.; Chair of Epidemiology, IBE, Faculty of Medicine, Ludwig-Maximilians-Universität München, München, Germany.
Körner A; LIFE Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany.; Department of Women and Child Health, Hospital for Children and Adolescents, University of Leipzig, Leipzig, Germany.; Center for Pediatric Research, University of Leipzig, Leipzig, Germany.
Mahajan A; Wellcome Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK.
Campbell A; Center for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK.
Freedman BI; Section on Nephrology, Internal Medicine, Wake Forest School of Medicine, Winston-Salem, NC, USA.
Spedicati B; Department of Medicine, Surgery and Health Sciences, University of Trieste, Trieste, Italy.
Ponte B; Service de Néphrologie et Hypertension, Medicine Department, Geneva University Hospitals, Geneva, Switzerland.
Schöttker B; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Network Aging Research, University of Heidelberg, Heidelberg, Germany.
Brumpton B; K. G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.; Clinic of Medicine, St. Olavs Hospital, Trondheim University Hospital, Trondheim, 7030, Norway.; HUNT Research Centre, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Levanger, 7600, Norway.
Banas B; Department of Nephrology, University Hospital Regensburg, Regensburg, Germany.
Krämer BK; Vth Department of Medicine (Nephrology, Hypertensiology, Endocrinology, Diabetology, Rheumatology, Pneumology), Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.
Jung B; Department of Population Medicine and Lifestyle Diseases Prevention, Medical University of Bialystok, Bialystok, Poland.; Department of Nephrology, University Hospital Regensburg, Regensburg, Germany.; Department of Nephrology and Rheumatology, Kliniken Südostbayern, Traunstein, Germany.
Åsvold BO; K. G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Endocrinology, Clinic of Medicine, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway.
Smith BH; Division of Population Health and Genomics, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK.
Ning B; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.
Penninx BWJH; Department of Psychiatry, VU University Medical Centre, Amsterdam, The Netherlands.
Vanderwerff BR; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, 48109, USA.; Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, 48109, USA.
Psaty BM; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.; Department of Epidemiology, University of Washington, Seattle, WA, USA.; Department of Health Systems and Population Health, University of Washington, Seattle, WA, USA.
Kammerer CM; Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA.
Langefeld CD; Department of Biostatistics and Data Science, Wake Forest School of Medicine, Winston-Salem, NC, USA.
Hayward C; Medical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK.
Spracklen CN; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA.; Department of Biostatistics and Epidemiology, University of Massachusetts Amherst, Amherst, MA, USA.
Robinson-Cohen C; Department of Veteran's Affairs, Tennessee Valley Healthcare System (626)/Vanderbilt University, Nashville, TN, USA.; Vanderbilt University Medical Center, Division of Nephrology and Hypertension, Vanderbilt Center for Kidney Disease and Integrated Program for Acute Kidney Injury Research, and Vanderbilt Precision Nephrology Program Nashville, Nashville, TN, USA.
Hartman CA; Interdisciplinary Center of Psychopathology and Emotion Regulation (ICPE), University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Lindgren CM; Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, OX3 7LF, UK.
Wang C; Genome Institute of Singapore, Agency for Science Technology and Research, Singapore, Singapore.; School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Sabanayagam C; Singapore Eye Research Institute, Singapore National Eye Center, Singapore, Singapore.; Ophthalmology and Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore.
Heng CK; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Khoo Teck Puat-National University Children's Medical Institute, National University Health System, Singapore, Singapore.
Lanzani C; Nephrology and Dialysis Unit, Genomics of Renal Diseases and Hypertension Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Khor CC; Genome Institute of Singapore, Agency for Science Technology and Research, Singapore, Singapore.; Singapore Eye Research Institute, Singapore National Eye Center, Singapore, Singapore.
Cheng CY; Singapore Eye Research Institute, Singapore National Eye Center, Singapore, Singapore.; Ophthalmology and Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore.
Fuchsberger C; Eurac Research, Institute for Biomedicine (affiliated with the University of Lübeck), Bolzano, Italy.
Gieger C; Institute of Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany.; Research Unit Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.
Shaffer CM; Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA.
Schulz CA; Department of Clincial Sciences in Malmö, Lund University, Malmö, Sweden.
Willer CJ; Department of Internal Medicine, Division of Cardiology, University of Michigan, Ann Arbor, MI, 48109, USA.; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, 48109, USA.; Department of Human Genetics, University of Michigan, Ann Arbor, MI, 48109, USA.
Chasman DI; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.
Gudbjartsson DF; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland.; Iceland School of Engineering and Natural Sciences, University of Iceland, Reykjavik, Iceland.
Ruggiero D; Institute of Genetics and Biophysics 'Adriano Buzzati-Traverso'-CNR, Naples, Italy.; IRCCS Neuromed, Pozzilli, Italy.
Toniolo D; San Raffaele Research Institute, Milan, Italy.
Czamara D; Department of Translational Research in Psychiatry, Max Planck Institute of Psychiatry, Munich, Germany.
Porteous DJ; Center for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK.; Center for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.
Waterworth DM; Target Sciences-Genetics, GlaxoSmithKline, Collegeville, PA, USA.
Mascalzoni D; Eurac Research, Institute for Biomedicine (affiliated with the University of Lübeck), Bolzano, Italy.; Centre for Research Ethics & Bioethics, Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden.
Mook-Kanamori DO; Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, The Netherlands.; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.
Reilly DF; Genetics, Merck & Co., Inc, Kenilworth, NJ, USA.
Daw EW; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA.
Hofer E; Clinical Division of Neurogeriatrics, Department of Neurology, Medical University of Graz, Graz, Austria.; Institute for Medical Informatics, Statistics and Documentation, Medical University of Graz, Graz, Austria.
Boerwinkle E; Human Genetics Center, University of Texas Health Science Center, Houston, TX, USA.
Salvi E; Neuroalgology Unit, Fondazione IRCCS Istituto Neurologico 'Carlo Besta', Milan, Italy.
Bottinger EP; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Digital Health Center, Hasso Plattner Institute and University of Potsdam, Potsdam, Germany.
Tai ES; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore.; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore.; Duke - NUS Medical School, Singapore, Singapore.
Catamo E; Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo', Trieste, Italy.
Rizzi F; Bio4Dreams-Business Nursery for Life Sciences, Milan, Italy.; ePhood Scientific Unit, ePhood SRL, Milano, Italy.
Guo F; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Rivadeneira F; Department of Internal Medicine, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.; Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Guilianini F; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Sveinbjornsson G; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland.
Ehret G; Cardiology, Geneva University Hospitals, Geneva, Switzerland.
Waeber G; Department of Medicine, Internal Medicine, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Biino G; Institute of Molecular Genetics 'Luigi Luca Cavalli-Sforza', National Research Council of Italy, Pavia, Italy.
Girotto G; Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo', Trieste, Italy.; Department of Medicine, Surgery and Health Sciences, University of Trieste, Trieste, Italy.
Pistis G; Department of Psychiatry, University Hospital of Lausanne, Lausanne, Switzerland.
Nadkarni GN; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Division of Nephrology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Delgado GE; Vth Department of Medicine (Nephrology, Hypertensiology, Rheumatology, Endocrinology, Diabetology), Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.
Montgomery GW; Institute for Molecular Bioscience, University of Queensland, St Lucia, QLD, Australia.
Snieder H; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Campbell H; Centre for Global Health, Usher Institute, University of Edinburgh, Edinburgh, UK.
White HD; Green Lane Cardiovascular Service, Auckland City Hospital and University of Auckland, Auckland, New Zealand.
Gao H; MRC Centre for Environment and Health, Department of Epidemiology and Biostatistics, School of Public Health, Faculty of Medicine, Imperial College London, London, UK.
Stringham HM; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA.
Schmidt H; Research Unit Genetic Epidemiology, Gottfried Schatz Research Center for Cell Signaling, Metabolism and Aging, Medical University of Graz, Graz, Austria.
Li H; Singapore Eye Research Institute, Singapore National Eye Center, Singapore, Singapore.
Brenner H; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Network Aging Research, University of Heidelberg, Heidelberg, Germany.
Holm H; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland.
Kirsten H; Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany.; LIFE Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany.
Kramer H; Department of Public Health Sciences, Loyola University Chicago, Maywood, IL, USA.; Division of Nephrology and Hypertension, Loyola University Chicago, Chicago, IL, USA.
Rudan I; Centre for Global Health, Usher Institute, University of Edinburgh, Edinburgh, UK.
Nolte IM; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Tzoulaki I; MRC Centre for Environment and Health, Department of Epidemiology and Biostatistics, School of Public Health, Faculty of Medicine, Imperial College London, London, UK.; Dementia Research Institute, Imperial College London, London, UK.; Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, Greece.
Olafsson I; Department of Clinical Biochemistry, Landspitali University Hospital, Reykjavik, Iceland.
Martins J; Department of Translational Research in Psychiatry, Max Planck Institute of Psychiatry, Munich, Germany.
Cook JP; Department of Health Data Science, University of Liverpool, Liverpool, UK.
Wilson JF; Medical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK.; Centre for Global Health, Usher Institute, University of Edinburgh, Edinburgh, UK.
Halbritter J; Medical Department III-Endocrinology, Nephrology, Rheumatology, University of Leipzig Medical Center, Leipzig, Germany.; Department of Nephrology and Medical Intensive Care, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Felix JF; Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.; Department of Pediatrics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Divers J; Department of Biostatistics and Data Science, Wake Forest School of Medicine, Winston-Salem, NC, USA.
Kooner JS; Department of Cardiology, Ealing Hospital, London North West University Healthcare NHS Trust, Middlesex, UK.; Imperial College Healthcare NHS Trust, Imperial College London, London, UK.; MRC-PHE Center for Environment and Health, School of Public Health, Imperial College London, London, UK.; National Heart and Lung Institute, Imperial College London, London, UK.
Lee JJ; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore.
O'Connell J; University of Maryland School of Medicine, Baltimore, MD, USA.
Rotter JI; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institutefor Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA.
Liu J; Genome Institute of Singapore, Agency for Science Technology and Research, Singapore, Singapore.; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore.
Xu J; Beijing Institute of Ophthalmology, Beijing Key Laboratory of Ophthalmology and Visual Sciences, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Thiery J; LIFE Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany.; Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University of Leipzig, Leipzig, Germany.
Ärnlöv J; Division of Family Medicine and Primary Care, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden.; School of Health and Social Studies, Dalarna University, Stockholm, Sweden.
Kuusisto J; University of Eastern Finland, Kuopio, Finland.; Kuopio University Hospital, Kuopio, Finland.
Jakobsdottir J; Icelandic Heart Association, Kopavogur, Iceland.; The Center of Public Health Sciences, University of Iceland, Reykjavík, Iceland.
Tremblay J; Montreal University Hospital Research Center, CHUM, Montreal, QC, Canada.; CRCHUM, Montreal, QC, Canada.
Chambers JC; MRC Centre for Environment and Health, Department of Epidemiology and Biostatistics, School of Public Health, Faculty of Medicine, Imperial College London, London, UK.; Department of Cardiology, Ealing Hospital, London North West University Healthcare NHS Trust, Middlesex, UK.; Imperial College Healthcare NHS Trust, Imperial College London, London, UK.; MRC-PHE Center for Environment and Health, School of Public Health, Imperial College London, London, UK.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.
Whitfield JB; QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.
Gaziano JM; Department of Internal Medicine, Harvard Medical School, Boston, MA, USA.; VA Cooperative Studies Program, VA Boston Healthcare System, Boston, MA, USA.
Marten J; Medical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK.
Coresh J; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Jonas JB; Beijing Institute of Ophthalmology, Beijing Key Laboratory of Ophthalmology and Visual Sciences, Beijing Tongren Hospital, Capital Medical University, Beijing, China.; Department of Ophthalmology, Medical Faculty Mannheim, University Heidelberg, Mannheim, Germany.; Instituteof Molecular and Clinical Ophthalmology, Basel, Switzerland.; Privatpraxis Prof Jonas und Dr Panda-Jonas, Heidelberg, Germany.
Mychaleckyj JC; Center for Public Health Genomics, University of Virginia, Charlottesville, Charlottesville, VA, USA.
Christensen K; Danish Aging Research Center, University of Southern Denmark, Odense C, Denmark.
Eckardt KU; Intensive Care Medicine, Charité, Berlin, Germany.; Department of Nephrology and Hypertension, Friedrich Alexander University Erlangen-Nürnberg (FAU), Erlangen, Germany.
Mohlke KL; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA.
Endlich K; DZHK (German Center for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.; Department of Anatomy and Cell Biology, University Medicine Greifswald, Greifswald, Germany.
Dittrich K; Department of Women and Child Health, Hospital for Children and Adolescents, University of Leipzig, Leipzig, Germany.; Center for Pediatric Research, University of Leipzig, Leipzig, Germany.
Ryan KA; Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine, Baltimore, MD, USA.
Rice KM; Department of Biostatistics, University of Washington, Seattle, WA, USA.
Taylor KD; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institutefor Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA.
Ho K; Geisinger Research, Biomedical and Translational Informatics Institute, Rockville, MD, USA.; Department of Nephrology, Geisinger, Danville, PA, USA.
Nikus K; Department of Cardiology, Heart Center, Tampere University Hospital, Tampere, Finland.; Department of Cardiology, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Matsuda K; Laboratory of Clinical Genome Sequencing, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, Japan.
Strauch K; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Chair of Genetic Epidemiology, IBE, Faculty of Medicine, Ludwig-Maximilians-Universität München, München, Germany.; Institute of Medical Biostatistics, Epidemiology and Informatics (IMBEI), University Medical Center, Johannes Gutenberg University, Mainz, Germany.
Miliku K; Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.; Department of Pediatrics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Hveem K; K. G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.
Lind L; Cardiovascular Epidemiology, Department of Medical Sciences, Uppsala University, Uppsala, Sweden.
Wallentin L; Cardiology, Department of Medical Sciences, Uppsala University, Uppsala, Sweden.; Uppsala Clinical Research Center, Uppsala University, Uppsala, Sweden.
Yerges-Armstrong LM; Target Sciences-Genetics, GlaxoSmithKline, Collegeville, PA, USA.
Raffield LM; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA.
Phillips LS; Atlanta VA Health Care System, Decatur, GA, USA.; Division of Endocrinology and Metabolism, Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA.
Launer LJ; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Intramural Research Program, US National Institutes of Health, Bethesda, MD, USA.
Lyytikäinen LP; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Lange LA; Division of Biomedical Informatics and Personalized Medicine, School of Medicine, University of Colorado Denver-Anschutz Medical Campus, Aurora, CO, USA.
Citterio L; Nephrology and Dialysis Unit, Genomics of Renal Diseases and Hypertension Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Klaric L; Medical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK.
Ikram MA; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Ising M; Max Planck Institute of Psychiatry, Munich, Germany.
Kleber ME; Vth Department of Medicine (Nephrology, Hypertensiology, Rheumatology, Endocrinology, Diabetology), Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.; SYNLAB MVZ Humangenetik Mannheim, Mannheim, Germany.
Francescatto M; Department of Medicine, Surgery and Health Sciences, University of Trieste, Trieste, Italy.
Concas MP; Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo', Trieste, Italy.
Ciullo M; Institute of Genetics and Biophysics 'Adriano Buzzati-Traverso'-CNR, Naples, Italy.; IRCCS Neuromed, Pozzilli, Italy.
Piratsu M; Institute of Genetic and Biomedical Research, National Research Council of Italy, Cagliari, Italy.
Orho-Melander M; Department of Clincial Sciences in Malmö, Lund University, Malmö, Sweden.
Laakso M; University of Eastern Finland, Kuopio, Finland.; Kuopio University Hospital, Kuopio, Finland.
Loeffler M; Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany.; LIFE Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany.
Perola M; Finnish Institute for Health and Welfare, Helsinki, Finland.; Research Program for Clinical and Molecular Metabolism, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
de Borst MH; Division of Nephrology, Department of Internal Medicine, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Gögele M; Eurac Research, Institute for Biomedicine (affiliated with the University of Lübeck), Bolzano, Italy.
Bianca M; Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo', Trieste, Italy.
Lukas MA; Target Sciences-Genetics, GlaxoSmithKline, Albuquerque, NM, USA.
Feitosa MF; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA.
Biggs ML; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.; Department of Biostatistics, University of Washington, Seattle, WA, USA.
Wojczynski MK; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA.
Kavousi M; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Kanai M; Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Japan.; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.
Akiyama M; Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Japan.; Department of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Yasuda M; Singapore Eye Research Institute, Singapore National Eye Center, Singapore, Singapore.; Department of Ophthalmology, Tohoku University Graduate School of Medicine, Miyagi, Japan.
Nauck M; DZHK (German Center for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.; Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany.
Waldenberger M; Institute of Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Research Unit Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; DZHK (German Center for Cardiovascular Research), Partner Site Munich Heart Alliance, Munich, Germany.
Chee ML; Singapore Eye Research Institute, Singapore National Eye Center, Singapore, Singapore.
Chee ML; Singapore Eye Research Institute, Singapore National Eye Center, Singapore, Singapore.
Boehnke M; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA.
Preuss MH; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Stumvoll M; Medical Department III-Endocrinology, Nephrology, Rheumatology, University of Leipzig Medical Center, Leipzig, Germany.
Province MA; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA.
Evans MK; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Intramural Research Program, US National Institutes of Health, Baltimore, MD, USA.
O'Donoghue ML; Cardiovascular Division, Brigham and Women's Hospital, Boston, MA, USA.; TIMI Study Group, Boston, MA, USA.
Kubo M; RIKEN Center for Integrative Medical Sciences (IMS), Yokohama (Kanagawa), Japan.
Kähönen M; Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland.; Department of Clinical Physiology, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Kastarinen M; Kuopio University Hospital, Kuopio, Finland.
Nalls MA; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA.; Data Tecnica International, Glen Echo, MD, USA.
Kuokkanen M; Research Program for Clinical and Molecular Metabolism, Faculty of Medicine, University of Helsinki, Helsinki, Finland.; The Department of Public Health and Welfare, Finnish Institute for Health and Welfare, Helsinki, Finland.; South Texas Diabetes and Obesity Institute and Department of Human Genetics, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX, USA.
Ghanbari M; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.; Department of Genetics, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Bochud M; Center for Primary Care and Public Health (Unisanté), University of Lausanne, 1010, Lausanne, Switzerland.
Josyula NS; Department of Population Health Sciences, Geisinger Health, 100 N. Academy Ave., Danville, PA, USA.
Martin NG; QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.
Tan NYQ; Singapore Eye Research Institute, Singapore National Eye Center, Singapore, Singapore.
Palmer ND; Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC, USA.
Pirastu N; Centre for Global Health, Usher Institute, University of Edinburgh, Edinburgh, UK.
Schupf N; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Medical Center, New York, NY, USA.
Verweij N; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Hutri-Kähönen N; Tampere Centre for Skills Training and Simulation, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Mononen N; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Bansal N; Division of Nephrology, University of Washington, Seattle, WA, USA.; Kidney Research Institute, University of Washington, Seattle, WA, USA.
Devuyst O; Institute of Physiology, University of Zurich, Zurich, Switzerland.
Melander O; Department of Clincial Sciences in Malmö, Lund University, Malmö, Sweden.
Raitakari OT; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland.; Research Center of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland.; Centre for Population Health Research, University of Turku and Turku University Hospital, Turku, Finland.
Polasek O; Faculty of Medicine, University of Split, Split, Croatia.; Algebra University College, Ilica 242, Zagreb, Croatia.
Manunta P; Nephrology and Dialysis Unit, Genomics of Renal Diseases and Hypertension Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Gasparini P; Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo', Trieste, Italy.; Department of Medicine, Surgery and Health Sciences, University of Trieste, Trieste, Italy.
Mishra PP; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Sulem P; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland.
Magnusson PKE; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Elliott P; MRC Centre for Environment and Health, Department of Epidemiology and Biostatistics, School of Public Health, Faculty of Medicine, Imperial College London, London, UK.; Dementia Research Institute, Imperial College London, London, UK.; Imperial College NIHR Biomedical Research Center, Imperial College London, London, UK.; Health Data Research UK-London, London, UK.
Ridker PM; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.
Hamet P; Montreal University Hospital Research Center, CHUM, Montreal, QC, Canada.; Medpharmgene, Montreal, QC, Canada.
Svensson PO; Department of Clinical Science and Education, Karolinska Institutet, Södersjukhuset, Stockholm, Sweden.; Department of Cardiology, Södersjukhuset, Stockholm, Sweden.
Joshi PK; Centre for Global Health, Usher Institute, University of Edinburgh, Edinburgh, UK.
Kovacs P; Medical Department III-Endocrinology, Nephrology, Rheumatology, University of Leipzig Medical Center, Leipzig, Germany.; Integrated Research and Treatment Center Adiposity Diseases, University of Leipzig, Leipzig, Germany.
Pramstaller PP; Eurac Research, Institute for Biomedicine (affiliated with the University of Lübeck), Bolzano, Italy.
Rossing P; Steno Diabetes Center Copenhagen, Herlev, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Vollenweider P; Department of Medicine, Internal Medicine, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
van der Harst P; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Dorajoo R; Genome Institute of Singapore, Agency for Science Technology and Research, Singapore, Singapore.
Sim RZH; Singapore Eye Research Institute, Singapore National Eye Center, Singapore, Singapore.
Burkhardt R; LIFE Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany.; Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University of Leipzig, Leipzig, Germany.; Institute of Clinical Chemistry and Laboratory Medicine, University Hospital Regensburg, Regensburg, Germany.
Tao R; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, USA.; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA.
Noordam R; Section of Gerontology and Geriatrics, Department of Internal Medicine, Leiden University Medical Center, Leiden, The Netherlands.
Mägi R; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia.
Schmidt R; Clinical Division of Neurogeriatrics, Department of Neurology, Medical University of Graz, Graz, Austria.
de Mutsert R; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.
Rueedi R; Department of Computational Biology, University of Lausanne, Lausanne, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, Switzerland.
van Dam RM; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore.; Department of Exercise and Nutrition Sciences, Milken Institute School of Public Health, The George Washington University, Washington, DC, USA.
Carroll RJ; Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA.
Gansevoort RT; Division of Nephrology, Department of Internal Medicine, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Loos RJF; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; The Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Novo Nordisk Foundation Center for Basic Metabolic Research, Department of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Felicita SC; San Raffaele Research Institute, Milan, Italy.
Sedaghat S; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Padmanabhan S; Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK.
Freitag-Wolf S; Institute of Medical Informatics and Statistics, Kiel University, University Hospital Schleswig-Holstein, Kiel, Germany.
Pendergrass SA; Geisinger Research, Biomedical and Translational Informatics Institute, Danville, PA, USA.
Graham SE; Department of Internal Medicine, Division of Cardiology, University of Michigan, Ann Arbor, MI, 48109, USA.
Gordon SD; QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.
Hwang SJ; NHLBI's Framingham Heart Study, Framingham, MA, USA.; The Center for Population Studies, NHLBI, Framingham, MA, USA.
Kerr SM; Medical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK.
Vaccargiu S; Institute of Genetic and Biomedical Research, National Research Council of Italy, Cagliari, Italy.
Patil SB; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, 48109, USA.; Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, 48109, USA.; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, 48109, USA.
Hallan S; Department of Clinical and Molecular Medicine, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Nephrology, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway.
Bakker SJL; Division of Nephrology, Department of Internal Medicine, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Lim SC; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore.; Diabetes Center, Khoo Teck Puat Hospital, Singapore, Singapore.
Lucae S; Max Planck Institute of Psychiatry, Munich, Germany.
Vogelezang S; Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.; Department of Pediatrics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Bergmann S; Department of Computational Biology, University of Lausanne, Lausanne, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, Switzerland.
Corre T; Center for Primary Care and Public Health (Unisanté), University of Lausanne, 1010, Lausanne, Switzerland.; Department of Computational Biology, University of Lausanne, Lausanne, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, Switzerland.
Ahluwalia TS; Steno Diabetes Center Copenhagen, Herlev, Denmark.; The Bioinformatics Center, Department of Biology, Faculty of Science, University of Copenhagen, Copenhagen, Denmark.
Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Boutin TS; Medical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK.
Meitinger T; DZHK (German Center for Cardiovascular Research), Partner Site Munich Heart Alliance, Munich, Germany.; Institute of Human Genetics, Helmholtz Zentrum München, Neuherberg, Germany.; Institute of Human Genetics, Technische Universität München, Munich, Germany.
Wong TY; Singapore Eye Research Institute, Singapore National Eye Center, Singapore, Singapore.; Ophthalmology and Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore.
Bergler T; Department of Nephrology, University Hospital Regensburg, Regensburg, Germany.
Rabelink TJ; Section of Nephrology, Department of Internal Medicine, Leiden University Medical Center, Leiden, The Netherlands.; Einthoven Laboratory of Experimental Vascular Research, Leiden University Medical Center, Leiden, The Netherlands.
Esko T; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia.; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, USA.
Haller T; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia.
Thorsteinsdottir U; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland.; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland.
Völker U; DZHK (German Center for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.; Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany.
Foo VHX; Singapore Eye Research Institute, Singapore National Eye Center, Singapore, Singapore.
Salomaa V; Finnish Institute for Health and Welfare, Helsinki, Finland.
Vitart V; Medical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK.
Giedraitis V; Molecular Geriatrics, Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden.
Gudnason V; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland.; Icelandic Heart Association, Kopavogur, Iceland.
Jaddoe VWV; Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.; Department of Pediatrics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Huang W; Department of Genetics, Shanghai-MOST Key Laboratory of Health and Disease Genomics, Chinese National Human Genome Center, Shanghai, China.; Shanghai Industrial Technology Institute, Shanghai, China.
Zhang W; MRC Centre for Environment and Health, Department of Epidemiology and Biostatistics, School of Public Health, Faculty of Medicine, Imperial College London, London, UK.; Department of Cardiology, Ealing Hospital, London North West University Healthcare NHS Trust, Middlesex, UK.
Wei WB; Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Kiess W; LIFE Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany.; Department of Women and Child Health, Hospital for Children and Adolescents, University of Leipzig, Leipzig, Germany.; Center for Pediatric Research, University of Leipzig, Leipzig, Germany.
März W; Vth Department of Medicine (Nephrology, Hypertensiology, Rheumatology, Endocrinology, Diabetology), Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.; Synlab Academy, Synlab Holding Deutschland GmbH, Mannheim, Germany.; Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria.
Koenig W; DZHK (German Center for Cardiovascular Research), Partner Site Munich Heart Alliance, Munich, Germany.; Deutsches Herzzentrum München, Technische Universität München, Munich, Germany.; Institute of Epidemiology and Medical Biometry, University of Ulm, Ulm, Germany.
Lieb W; Institute of Epidemiology and Biobank Popgen, Kiel University, Kiel, Germany.
Gao X; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Sim X; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore.
Wang YX; Beijing Institute of Ophthalmology, Beijing Key Laboratory of Ophthalmology and Visual Sciences, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Friedlander Y; School of Public Health and Community Medicine, Hebrew University of Jerusalem, Jerusalem, Israel.
Tham YC; Singapore Eye Research Institute, Singapore National Eye Center, Singapore, Singapore.
Kamatani Y; Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Japan.; Laboratory of Complex Trait Genomics, Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, Japan.
Okada Y; Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Japan.; Laboratory for Systems Genetics, RIKEN Center for Integrative Medical Sciences (IMS), Osaka, Japan.; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Osaka, Japan.
Milaneschi Y; Department of Psychiatry, VU University Medical Centre, Amsterdam, The Netherlands.
Yu Z; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.; Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Massachusetts General Hospital, Boston, MA, USA.
Stark KJ; Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany.
Stefansson K; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland.; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland.
Böger CA; Department of Population Medicine and Lifestyle Diseases Prevention, Medical University of Bialystok, Bialystok, Poland.; Department of Nephrology, University Hospital Regensburg, Regensburg, Germany.; Department of Nephrology and Rheumatology, Kliniken Südostbayern, Traunstein, Germany.
Hung AM; Department of Veteran's Affairs, Tennessee Valley Healthcare System (626)/Vanderbilt University, Nashville, TN, USA.; Vanderbilt University Medical Center, Division of Nephrology and Hypertension, Vanderbilt Center for Kidney Disease and Integrated Program for Acute Kidney Injury Research, and Vanderbilt Precision Nephrology Program Nashville, Nashville, TN, USA.
Kronenberg F; Department of Genetics and Pharmacology, Institute of Genetic Epidemiology, Medical University of Innsbruck, Innsbruck, Austria.
Köttgen A; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.; Institute of Genetic Epidemiology, Department of Data Driven Medicine, Faculty of Medicine and Medical Center-University of Freiburg, Freiburg, Germany.
Pattaro C; Eurac Research, Institute for Biomedicine (affiliated with the University of Lübeck), Bolzano, Italy.
Heid IM; Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany. .; Pokaż więcej
Corporate Authors:: Lifelines cohort study
DiscovEHR/MyCode study
VA Million Veteran Program
Źródło:: Communications biology [Commun Biol] 2022 Jun 13; Vol. 5 (1), pp. 580. Date of Electronic Publication: 2022 Jun 13.
Typ publikacji:: Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:: Diabetes Mellitus*
Diabetic Nephropathies*/genetics
Creatinine ; Genome-Wide Association Study ; Glomerular Filtration Rate/genetics ; Humans ; Kidney

Czasopismo naukowe

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Tytuł:: Author Correction: Identification of genetic effects underlying type 2 diabetes in South Asian and European populations.
Autorzy:: Loh M; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, 308232, Singapore.; Department of Epidemiology and Biostatistics, Imperial College London, London, W2 1PG, UK.
Zhang W; Department of Epidemiology and Biostatistics, Imperial College London, London, W2 1PG, UK.; Department of Cardiology, Ealing Hospital, London North West Healthcare NHS Trust, Middlesex, UB1 3HW, UK.
Ng HK; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, 308232, Singapore.
Schmid K; Institute of Computational Biology, Deutsches Forschungszentrum für Gesundheit und Umwelt, Helmholtz Zentrum München, 85764, Neuherberg, Germany.; Department of Informatics, Technical University of Munich, 85748, Garching bei München, Neuherberg, Germany.
Lamri A; Department of Medicine, McMaster University, Hamilton, ON, Canada.; Population Health Research Institute, Hamilton Health Sciences and McMaster University, Hamilton, ON, Canada.
Tong L; The University of Chicago, Biological Sciences Division, Public Health Sciences, 5841 South Maryland Avenue, MC2000, Chicago, IL, 60637, USA.
Ahmad M; Genomic Research on Complex diseases, CSIR-Centre for Cellular and Molecular Biology (CSIR-CCMB), Hyderabad, India.
Lee JJ; Translational Medicine and Human Genetics, Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.; Department of Medicine, Mayo Hospital, Lahore, Pakistan.
Ng MCY; Center for Genomics and Personalized Medicine Research, Center for Diabetes Research, Wake Forest School of Medicine, Winston-Salem, NC, 37215, USA.; Vanderbilt Genetics Institute, Division of Genetic Medicine, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.
Petty LE; Vanderbilt Genetics Institute, Division of Genetic Medicine, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.; Human Genetics Center, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, 77030, USA.
Spracklen CN; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.; Department of Biostatistics and Epidemiology, University of Massachusetts, Amherst, MA, 01003, USA.
Takeuchi F; Department of Gene Diagnostics and Therapeutics, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan.
Islam MT; U Chicago Research Bangladesh, House#4, Road#2b, Sector#4, Uttara, Dhaka, 1230, Bangladesh.
Jasmine F; The University of Chicago, Biological Sciences Division, Public Health Sciences, 5841 South Maryland Avenue, MC2000, Chicago, IL, 60637, USA.
Kasturiratne A; Department of Public Health, Faculty of Medicine, University of Kelaniya, Kelaniya, Sri Lanka.
Kibriya M; The University of Chicago, Biological Sciences Division, Public Health Sciences, 5841 South Maryland Avenue, MC2000, Chicago, IL, 60637, USA.
Mohlke KL; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.
Paré G; Population Health Research Institute, Hamilton Health Sciences and McMaster University, Hamilton, ON, Canada.; Department of Pathology and Molecular Medicine, McMaster University, Hamilton, ON, Canada.
Prasad G; Academy of Scientific and Innovative Research, CSIR-Institute of Genomics and Integrative Biology Campus, New Delhi, 110020, India.; Systems Genomics Laboratory, School of Biotechnology, Jawaharlal Nehru University, New Delhi, 110067, India.
Shahriar M; The University of Chicago, Biological Sciences Division, Public Health Sciences, 5841 South Maryland Avenue, MC2000, Chicago, IL, 60637, USA.
Chee ML; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.
de Silva HJ; Department of Medicine, Faculty of Medicine, University of Kelaniya, Kelaniya, Sri Lanka.
Engert JC; Department of Medicine, McGill University, Montreal, QC, Canada.; Department of Human Genetics, McGill University, Montreal, QC, Canada.
Gerstein HC; Department of Medicine, McMaster University, Hamilton, ON, Canada.; Population Health Research Institute, Hamilton Health Sciences and McMaster University, Hamilton, ON, Canada.; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada.
Mani KR; Genomic Research on Complex diseases, CSIR-Centre for Cellular and Molecular Biology (CSIR-CCMB), Hyderabad, India.
Sabanayagam C; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.; Ophthalmology & Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore.
Vujkovic M; Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, Pennsylvania, 19104, USA.
Wickremasinghe AR; Department of Public Health, Faculty of Medicine, University of Kelaniya, Kelaniya, Sri Lanka.
Wong TY; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.; Ophthalmology & Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Yajnik CS; Diabetes Unit, King Edward Memorial Hospital and Research Centre, Pune, India.
Yusuf S; Department of Medicine, McMaster University, Hamilton, ON, Canada.; Population Health Research Institute, Hamilton Health Sciences and McMaster University, Hamilton, ON, Canada.; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada.
Ahsan H; The University of Chicago, Biological Sciences Division, Public Health Sciences, 5841 South Maryland Avenue, MC2000, Chicago, IL, 60637, USA.
Bharadwaj D; Academy of Scientific and Innovative Research, CSIR-Institute of Genomics and Integrative Biology Campus, New Delhi, 110020, India.; Systems Genomics Laboratory, School of Biotechnology, Jawaharlal Nehru University, New Delhi, 110067, India.
Anand SS; Department of Medicine, McMaster University, Hamilton, ON, Canada.; Population Health Research Institute, Hamilton Health Sciences and McMaster University, Hamilton, ON, Canada.; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada.
Below JE; Vanderbilt Genetics Institute, Division of Genetic Medicine, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.; Human Genetics Center, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, 77030, USA.
Boehnke M; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, 48109, USA.
Bowden DW; Department of Medicine, Mayo Hospital, Lahore, Pakistan.; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC, 37215, USA.
Chandak GR; Genomic Research on Complex diseases, CSIR-Centre for Cellular and Molecular Biology (CSIR-CCMB), Hyderabad, India.; JSS Academy of Health Education of Research, Mysuru, India.; Science and Engineering Research Board, Department of Science and Technology, Ministry of Science and technology, Government of India, New Delhi, India.
Cheng CY; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.; Ophthalmology & Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Kato N; Department of Gene Diagnostics and Therapeutics, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan.
Mahajan A; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, OX3 7BN, UK.; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7BN, UK.
Sim X; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.
McCarthy MI; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, OX3 7BN, UK.; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7BN, UK.; Oxford NIHR Biomedical Research Centre, Churchill Hosptial, Oxford University Hospitals NHS Foundation Trust, Oxford, OX3 7LE, UK.
Morris AP; Department of Biostatistics, University of Liverpool, Liverpool, L69 3GL, UK.; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia.; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK.
Kooner JS; Department of Cardiology, Ealing Hospital, London North West Healthcare NHS Trust, Middlesex, UB1 3HW, UK. .; Imperial College Healthcare NHS Trust, Imperial College London, London, W12 0HS, UK. .; MRC-PHE Centre for Enviroment and Health, Imperial College London, London, W2 1PG, UK. .; National Heart and Lung Institute, Imperial College London, London, W12 0NN, UK. .
Saleheen D; Center for Non-Communicable Diseases, Karachi, Pakistan. .; Department of Medicine, Columbia University Irving Medical Center, New York, NY, 10032, USA. .; Department of Cardiology, Columbia University Irving Medical Center, New York, NY, 10032, USA. .
Chambers JC; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, 308232, Singapore. .; Department of Epidemiology and Biostatistics, Imperial College London, London, W2 1PG, UK. .; Department of Cardiology, Ealing Hospital, London North West Healthcare NHS Trust, Middlesex, UB1 3HW, UK. .; Imperial College Healthcare NHS Trust, Imperial College London, London, W12 0HS, UK. .; MRC-PHE Centre for Enviroment and Health, Imperial College London, London, W2 1PG, UK. .; Pokaż więcej
Źródło:: Communications biology [Commun Biol] 2022 May 05; Vol. 5 (1), pp. 441. Date of Electronic Publication: 2022 May 05.
Typ publikacji:: Published Erratum

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Skocz do pozycji: 4.

Tytuł:: Identification of genetic effects underlying type 2 diabetes in South Asian and European populations.
Autorzy:: Loh M; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, 308232, Singapore.; Department of Epidemiology and Biostatistics, Imperial College London, London, W2 1PG, UK.
Zhang W; Department of Epidemiology and Biostatistics, Imperial College London, London, W2 1PG, UK.; Department of Cardiology, Ealing Hospital, London North West Healthcare NHS Trust, Middlesex, UB1 3HW, UK.
Ng HK; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, 308232, Singapore.
Schmid K; Institute of Computational Biology, Deutsches Forschungszentrum für Gesundheit und Umwelt, Helmholtz Zentrum München, 85764, Neuherberg, Germany.; Department of Informatics, Technical University of Munich, 85748, Garching bei München, Neuherberg, Germany.
Lamri A; Department of Medicine, McMaster University, Hamilton, ON, Canada.; Population Health Research Institute, Hamilton Health Sciences and McMaster University, Hamilton, ON, Canada.
Tong L; The University of Chicago, Biological Sciences Division, Public Health Sciences, 5841 South Maryland Avenue, MC2000, Chicago, IL, 60637, USA.
Ahmad M; Genomic Research on Complex diseases, CSIR-Centre for Cellular and Molecular Biology (CSIR-CCMB), Hyderabad, India.
Lee JJ; Translational Medicine and Human Genetics, Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.; Department of Medicine, Mayo Hospital, Lahore, Pakistan.
Ng MCY; Center for Genomics and Personalized Medicine Research, Center for Diabetes Research, Wake Forest School of Medicine, Winston-Salem, NC, 37215, USA.; Vanderbilt Genetics Institute, Division of Genetic Medicine, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.
Petty LE; Vanderbilt Genetics Institute, Division of Genetic Medicine, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.; Human Genetics Center, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, 77030, USA.
Spracklen CN; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.; Department of Biostatistics and Epidemiology, University of Massachusetts, Amherst, MA, 01003, USA.
Takeuchi F; Department of Gene Diagnostics and Therapeutics, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan.
Islam MT; U Chicago Research Bangladesh, House#4, Road#2b, Sector#4, Uttara, Dhaka, 1230, Bangladesh.
Jasmine F; The University of Chicago, Biological Sciences Division, Public Health Sciences, 5841 South Maryland Avenue, MC2000, Chicago, IL, 60637, USA.
Kasturiratne A; Department of Public Health, Faculty of Medicine, University of Kelaniya, Kelaniya, Sri Lanka.
Kibriya M; The University of Chicago, Biological Sciences Division, Public Health Sciences, 5841 South Maryland Avenue, MC2000, Chicago, IL, 60637, USA.
Mohlke KL; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.
Paré G; Population Health Research Institute, Hamilton Health Sciences and McMaster University, Hamilton, ON, Canada.; Department of Pathology and Molecular Medicine, McMaster University, Hamilton, ON, Canada.
Prasad G; Academy of Scientific and Innovative Research, CSIR-Institute of Genomics and Integrative Biology Campus, New Delhi, 110020, India.; Systems Genomics Laboratory, School of Biotechnology, Jawaharlal Nehru University, New Delhi, 110067, India.
Shahriar M; The University of Chicago, Biological Sciences Division, Public Health Sciences, 5841 South Maryland Avenue, MC2000, Chicago, IL, 60637, USA.
Chee ML; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.
de Silva HJ; Department of Medicine, Faculty of Medicine, University of Kelaniya, Kelaniya, Sri Lanka.
Engert JC; Department of Medicine, McGill University, Montreal, QC, Canada.; Department of Human Genetics, McGill University, Montreal, QC, Canada.
Gerstein HC; Department of Medicine, McMaster University, Hamilton, ON, Canada.; Population Health Research Institute, Hamilton Health Sciences and McMaster University, Hamilton, ON, Canada.; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada.
Mani KR; Genomic Research on Complex diseases, CSIR-Centre for Cellular and Molecular Biology (CSIR-CCMB), Hyderabad, India.
Sabanayagam C; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.; Ophthalmology & Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore.
Vujkovic M; Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, Pennsylvania, 19104, USA.
Wickremasinghe AR; Department of Public Health, Faculty of Medicine, University of Kelaniya, Kelaniya, Sri Lanka.
Wong TY; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.; Ophthalmology & Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Yajnik CS; Diabetes Unit, King Edward Memorial Hospital and Research Centre, Pune, India.
Yusuf S; Department of Medicine, McMaster University, Hamilton, ON, Canada.; Population Health Research Institute, Hamilton Health Sciences and McMaster University, Hamilton, ON, Canada.; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada.
Ahsan H; The University of Chicago, Biological Sciences Division, Public Health Sciences, 5841 South Maryland Avenue, MC2000, Chicago, IL, 60637, USA.
Bharadwaj D; Academy of Scientific and Innovative Research, CSIR-Institute of Genomics and Integrative Biology Campus, New Delhi, 110020, India.; Systems Genomics Laboratory, School of Biotechnology, Jawaharlal Nehru University, New Delhi, 110067, India.
Anand SS; Department of Medicine, McMaster University, Hamilton, ON, Canada.; Population Health Research Institute, Hamilton Health Sciences and McMaster University, Hamilton, ON, Canada.; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada.
Below JE; Vanderbilt Genetics Institute, Division of Genetic Medicine, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.; Human Genetics Center, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, 77030, USA.
Boehnke M; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, 48109, USA.
Bowden DW; Department of Medicine, Mayo Hospital, Lahore, Pakistan.; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC, 37215, USA.
Chandak GR; Genomic Research on Complex diseases, CSIR-Centre for Cellular and Molecular Biology (CSIR-CCMB), Hyderabad, India.; JSS Academy of Health Education of Research, Mysuru, India.; Science and Engineering Research Board, Department of Science and Technology, Ministry of Science and technology, Government of India, New Delhi, India.
Cheng CY; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.; Ophthalmology & Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Kato N; Department of Gene Diagnostics and Therapeutics, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan.
Mahajan A; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, OX3 7BN, UK.; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7BN, UK.
Sim X; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.
McCarthy MI; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, OX3 7BN, UK.; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7BN, UK.; Oxford NIHR Biomedical Research Centre, Churchill Hosptial, Oxford University Hospitals NHS Foundation Trust, Oxford, OX3 7LE, UK.
Morris AP; Department of Biostatistics, University of Liverpool, Liverpool, L69 3GL, UK.; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia.; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK.
Kooner JS; Department of Cardiology, Ealing Hospital, London North West Healthcare NHS Trust, Middlesex, UB1 3HW, UK. .; Imperial College Healthcare NHS Trust, Imperial College London, London, W12 0HS, UK. .; MRC-PHE Centre for Enviroment and Health, Imperial College London, London, W2 1PG, UK. .; National Heart and Lung Institute, Imperial College London, London, W12 0NN, UK. .
Saleheen D; Center for Non-Communicable Diseases, Karachi, Pakistan. .; Department of Medicine, Columbia University Irving Medical Center, New York, NY, 10032, USA. .; Department of Cardiology, Columbia University Irving Medical Center, New York, NY, 10032, USA. .
Chambers JC; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, 308232, Singapore. .; Department of Epidemiology and Biostatistics, Imperial College London, London, W2 1PG, UK. .; Department of Cardiology, Ealing Hospital, London North West Healthcare NHS Trust, Middlesex, UB1 3HW, UK. .; Imperial College Healthcare NHS Trust, Imperial College London, London, W12 0HS, UK. .; MRC-PHE Centre for Enviroment and Health, Imperial College London, London, W2 1PG, UK. .; Pokaż więcej
Źródło:: Communications biology [Commun Biol] 2022 Apr 07; Vol. 5 (1), pp. 329. Date of Electronic Publication: 2022 Apr 07.
Typ publikacji:: Journal Article; Meta-Analysis; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Diabetes Mellitus, Type 2*/epidemiology
Diabetes Mellitus, Type 2*/genetics
Genome-Wide Association Study*
Asian People/genetics ; Case-Control Studies ; Genetic Predisposition to Disease ; Humans ; Polymorphism, Single Nucleotide

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Tytuł:: Characterization and ex vivo evaluation of curcumin nanoethosomes for melanoma treatment.
Autorzy:: Nair RS; School of Pharmacy, Monash University Malaysia, Jalan Lagoon Selatan, Malaysia.; School of Pharmacy, The University of Nottingham Malaysia, Semenyih, Malaysia.
Billa N; College of Pharmacy, QU Health, Qatar University, Doha, Qatar.; Biomedical and Pharmaceutical Research Unit (BPRU), QU Health, Qatar University, Doha, Qatar.
Mooi LY; Faculty of Medicine & Health Sciences, Centre for Cancer Research, Universiti Tunku Abdul Rahman, Kajang, Malaysia.
Morris AP; School of Pharmacy, The University of Nottingham Malaysia, Semenyih, Malaysia.; Swansea University Medical School, Swansea University, Swansea, UK.; Pokaż więcej
Źródło:: Pharmaceutical development and technology [Pharm Dev Technol] 2022 Jan; Vol. 27 (1), pp. 72-82. Date of Electronic Publication: 2022 Jan 06.
Typ publikacji:: Journal Article
MeSH Terms:: Curcumin*/pharmacology
Melanoma*/drug therapy
Nanoparticles*
Drug Carriers ; Humans ; Particle Size ; Skin

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Skocz do pozycji: 6.

Tytuł:: Epigenome-wide association study of kidney function identifies trans-ethnic and ethnic-specific loci.
Autorzy:: Breeze CE; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, MD, USA. .; UCL Cancer Institute, University College London, London, WC1E 6BT, UK. .; Altius Institute for Biomedical Sciences, Seattle, WA, 98121, USA. .
Batorsky A; Department of Biostatistics, University of North Carolina, Chapel Hill, NC, 27516, USA.
Lee MK; Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC, 27709, USA.
Szeto MD; Division of Biomedical Informatics and Personalized Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Xu X; Division of Cardiovascular Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
McCartney DL; Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Crewe Road, Edinburgh, EH4 2XU, UK.
Jiang R; Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, 27701, USA.
Patki A; Department of Biostatistics, University of Alabama, Birmingham, AL, USA.
Kramer HJ; Department of Public Health Sciences and Medicine, Loyola University Chicago, Maywood, IL, USA.; Division of Nephrology and Hypertension, Loyola University Chicago, Maywood, IL, USA.
Eales JM; Division of Cardiovascular Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Raffield L; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA.
Lange L; Division of Biomedical Informatics and Personalized Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Lange E; Division of Biomedical Informatics and Personalized Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Durda P; Department of Pathology & Laboratory Medicine, Larner College of Medicine, University of Vermont, Burlington, VT, USA.
Liu Y; Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC, USA.
Tracy RP; Department of Pathology & Laboratory Medicine, Larner College of Medicine, University of Vermont, Burlington, VT, USA.; Department of Biochemistry, Larner College of Medicine, University of Vermont, Burlington, VT, USA.
Van Den Berg D; Center for Genetic Epidemiology, Department of Preventive Medicine, Keck School of Medicine of USC, University of Southern California, Los Angeles, CA, USA.
Evans KL; Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Crewe Road, Edinburgh, EH4 2XU, UK.
Kraus WE; Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC, USA.; Division of Cardiology, Department of Medicine, School of Medicine, Duke University, Durham, NC, USA.
Shah S; Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC, USA.; Division of Cardiology, Department of Medicine, School of Medicine, Duke University, Durham, NC, USA.
Tiwari HK; Department of Biostatistics, University of Alabama, Birmingham, AL, USA.
Hou L; Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Center for Global Oncology, Institute of Global Health, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Whitsel EA; Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA.; Department of Medicine, University of North Carolina, Chapel Hill, NC, 27599, USA.
Jiang X; Division of Cardiovascular Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Charchar FJ; School of Health and Life Sciences, Federation University Australia, Ballarat, VIC, Australia.; Department of Physiology, University of Melbourne, Parkville, VIC, Australia.; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.
Baccarelli AA; Laboratory of Environmental Epigenetics, Departments of Environmental Health Sciences and Epidemiology, Columbia University Mailman School of Public Health, New York, NY, USA.
Rich SS; Center for Public Health Genomics, University of Virginia, Charlottesville, VA, USA.
Morris AP; Centre for Genetics and Genomics Versus Arthritis, Centre for Musculoskeletal Research, The University of Manchester, Manchester, UK.
Irvin MR; Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, USA.
Arnett DK; College of Public Health, University of Kentucky, Lexington, KY, USA.
Hauser ER; Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC, USA.; Durham VA Health System, Durham, NC, 27705, USA.
Rotter JI; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA.
Correa A; Department of Medicine, University of Mississippi Medical Center, Jackson, MS, USA.
Hayward C; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Crewe Road, Edinburgh, EH4 2XU, UK.
Horvath S; Department of Human Genetics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, 90095, USA.; Department of Biostatistics, Fielding School of Public Health, University of California Los Angeles, Los Angeles, CA, 90095, USA.
Marioni RE; Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Crewe Road, Edinburgh, EH4 2XU, UK.
Tomaszewski M; Division of Cardiovascular Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.; Manchester Heart Centre and Manchester Academic Health Science Centre, Manchester University NHS Foundation Trust, Manchester, UK.
Beck S; UCL Cancer Institute, University College London, London, WC1E 6BT, UK.
Berndt SI; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, MD, USA.
London SJ; Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC, 27709, USA.
Mychaleckyj JC; Center for Public Health Genomics, University of Virginia, Charlottesville, VA, USA.
Franceschini N; Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA. .; Pokaż więcej
Corporate Authors:: NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, TOPMed MESA Multi-Omics Working Group
Źródło:: Genome medicine [Genome Med] 2021 Apr 30; Vol. 13 (1), pp. 74. Date of Electronic Publication: 2021 Apr 30.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Epigenesis, Genetic*
Epigenomics*/methods
Genome-Wide Association Study*
Quantitative Trait Loci*
Quantitative Trait, Heritable*
Kidney/*metabolism
Racial Groups/*genetics
CpG Islands ; DNA Methylation ; Gene Expression Regulation ; Genetic Variation ; Genetics, Population ; Glomerular Filtration Rate ; Humans ; Kidney Function Tests ; Phenotype

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Skocz do pozycji: 7.

Tytuł:: An evaluation of tocotrienol ethosomes for transdermal delivery using Strat-M membrane and excised human skin.
Autorzy:: Nair RS; School of Pharmacy, University of Nottingham Malaysia, Semenyih, Malaysia.; School of Pharmacy, Monash University Malaysia, Bandar Sunway, Malaysia.
Billa N; School of Pharmacy, University of Nottingham Malaysia, Semenyih, Malaysia.; College of Pharmacy, QU Health, Qatar University, Doha, Qatar.
Leong CO; Center for Cancer and Stem Cell Research, International Medical University, Kuala Lumpur, Malaysia.
Morris AP; School of Pharmacy, University of Nottingham Malaysia, Semenyih, Malaysia.; Swansea University Medical School, Swansea University, Swansea, UK.; Pokaż więcej
Źródło:: Pharmaceutical development and technology [Pharm Dev Technol] 2021 Feb; Vol. 26 (2), pp. 243-251. Date of Electronic Publication: 2020 Dec 15.
Typ publikacji:: Comparative Study; Journal Article
MeSH Terms:: Drug Delivery Systems*
Skin Absorption*
Skin/*metabolism
Tocotrienols/*administration & dosage
Administration, Cutaneous ; Cell Survival/drug effects ; HaCaT Cells ; Humans ; In Vitro Techniques ; Liposomes ; Particle Size ; Time Factors ; Tocotrienols/pharmacokinetics

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Tytuł:: Mapping DNA interaction landscapes in psoriasis susceptibility loci highlights KLF4 as a target gene in 9q31.
Autorzy:: Ray-Jones H; Centre for Genetics and Genomics Versus Arthritis, Division of Musculoskeletal and Dermatological Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.; Dermatology Centre, Manchester NIHR Biomedical Research Centre, Manchester Academic Health Science Centre, Salford Royal NHS Foundation Trust, Manchester, UK.
Duffus K; Centre for Genetics and Genomics Versus Arthritis, Division of Musculoskeletal and Dermatological Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.
McGovern A; Centre for Genetics and Genomics Versus Arthritis, Division of Musculoskeletal and Dermatological Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.
Martin P; Centre for Genetics and Genomics Versus Arthritis, Division of Musculoskeletal and Dermatological Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.; The Lydia Becker Institute of Immunology and Inflammation, The University of Manchester, Manchester, UK.
Shi C; Centre for Genetics and Genomics Versus Arthritis, Division of Musculoskeletal and Dermatological Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.
Hankinson J; Dermatology Centre, Manchester NIHR Biomedical Research Centre, Manchester Academic Health Science Centre, Salford Royal NHS Foundation Trust, Manchester, UK.
Gough O; Centre for Genetics and Genomics Versus Arthritis, Division of Musculoskeletal and Dermatological Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.
Yarwood A; Centre for Genetics and Genomics Versus Arthritis, Division of Musculoskeletal and Dermatological Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.; Dermatology Centre, Manchester NIHR Biomedical Research Centre, Manchester Academic Health Science Centre, Salford Royal NHS Foundation Trust, Manchester, UK.
Morris AP; Centre for Genetics and Genomics Versus Arthritis, Division of Musculoskeletal and Dermatological Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.
Adamson A; Genome Editing Unit, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.
Taylor C; Centre for Genetics and Genomics Versus Arthritis, Division of Musculoskeletal and Dermatological Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.
Ding J; Centre for Genetics and Genomics Versus Arthritis, Division of Musculoskeletal and Dermatological Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.
Gaddi VP; Centre for Genetics and Genomics Versus Arthritis, Division of Musculoskeletal and Dermatological Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.
Fu Y; Genes and Human Disease Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, 73104, USA.
Gaffney P; Genes and Human Disease Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, 73104, USA.
Orozco G; Centre for Genetics and Genomics Versus Arthritis, Division of Musculoskeletal and Dermatological Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.
Warren RB; Dermatology Centre, Manchester NIHR Biomedical Research Centre, Manchester Academic Health Science Centre, Salford Royal NHS Foundation Trust, Manchester, UK.
Eyre S; Centre for Genetics and Genomics Versus Arthritis, Division of Musculoskeletal and Dermatological Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK. .; Pokaż więcej
Źródło:: BMC biology [BMC Biol] 2020 May 04; Vol. 18 (1), pp. 47. Date of Electronic Publication: 2020 May 04.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Genetic Predisposition to Disease*
DNA/*genetics
Psoriasis/*genetics
Apoptosis ; Chromosome Mapping ; Genome-Wide Association Study ; HaCaT Cells ; Humans ; Kruppel-Like Factor 4

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Tytuł:: Pharmacogenomics of statin-related myopathy: Meta-analysis of rare variants from whole-exome sequencing.
Autorzy:: Floyd JS; Department of Medicine, University of Washington, Seattle, Washington, United States of America.
Bloch KM; MRC Centre for Drug Safety Science, Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, United Kingdom.
Brody JA; Department of Medicine, University of Washington, Seattle, Washington, United States of America.
Maroteau C; Division of Molecular and Clinical Medicine, University of Dundee, Dundee, United Kingdom.
Siddiqui MK; Division of Molecular and Clinical Medicine, University of Dundee, Dundee, United Kingdom.
Gregory R; Functional and Comparative Genomics, Institute of Integrative Biology, University of Liverpool, Liverpool, United Kingdom.
Carr DF; Department of Medicine, University of Washington, Seattle, Washington, United States of America.
Molokhia M; School of Population Health and Environmental Sciences, London, United Kingdom.
Liu X; Human Genetics Center, University of Texas Health Science Center, Houston, United States of America.
Bis JC; Department of Medicine, University of Washington, Seattle, Washington, United States of America.
Ahmed A; Medical School, University of Liverpool, Liverpool, United Kingdom.
Liu X; Functional and Comparative Genomics, Institute of Integrative Biology, University of Liverpool, Liverpool, United Kingdom.
Hallberg P; Department of Medical Sciences, Clinical Pharmacology and Science for Life Laboratory, Uppsala University, Uppsala University Hospital, Uppsala, Sweden.
Yue QY; Medical Products Agency, Uppsala, Sweden.
Magnusson PKE; Swedish Twin Registry, Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Brisson D; Clinical Lipidology and Rare Lipid Disorders Unit, Department of Medicine, Université de Montréal Community Gene Medicine Center, Lipid Clinic Chicoutimi Hospital and ECOGENE-21 Clinical and Translational Research Center, Chicoutimi, Quebec, Canada.
Wiggins KL; Department of Medicine, University of Washington, Seattle, Washington, United States of America.
Morrison AC; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, Texas, United States of America.
Khoury E; Clinical Lipidology and Rare Lipid Disorders Unit, Department of Medicine, Université de Montréal Community Gene Medicine Center, Lipid Clinic Chicoutimi Hospital and ECOGENE-21 Clinical and Translational Research Center, Chicoutimi, Quebec, Canada.
McKeigue P; Usher Institute of Population Health Sciences and Informatics, University of Edinburgh Medical School, Edinburgh, Scotland, United Kingdom.
Stricker BH; Department of Epidemiology, Erasmus Medical Centre, Rotterdam, the Netherlands.
Lapeyre-Mestre M; Paul Sabatier University - Toulouse III, UPS Toulouse, Laboratoire de Pharmacologie Medicale et Clinique, Toulouse, France.
Heckbert SR; Department of Epidemiology, University of Washington, Seattle, Washington, United States of America.
Gallagher AM; Clinical Practice Research Datalink (CPRD) Medicines and Healthcare Products Regulatory Agency, London, United Kingdom.
Chinoy H; Rheumatology Department, Salford Royal NHS Foundation Trust, Manchester Academic Health Science Centre, Salford, United Kingdom.
Gibbs RA; Human Genome Sequencing Center, Baylor College of Medicine, Houston, United States of America.
Bondon-Guitton E; Centre Hospitalier Universitaire de Toulouse, CHU Toulouse, Centre de Pharmacovigilance, Toulouse, France.
Tracy R; Departments of Pathology & Laboratory Medicine and Biochemistry, Larner College of Medicine, University of Vermont, Burlington, Vermont, United States of America.
Boerwinkle E; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, Texas, United States of America.
Gaudet D; Clinical Lipidology and Rare Lipid Disorders Unit, Department of Medicine, Université de Montréal Community Gene Medicine Center, Lipid Clinic Chicoutimi Hospital and ECOGENE-21 Clinical and Translational Research Center, Chicoutimi, Quebec, Canada.
Conforti A; U.O. Farmacologia, Policlinico 'Gb Rossi', Verona, Italy.
van Staa T; Division of Informatics, Imaging & Data Sciences, University of Manchester, Manchester, United Kingdom.
Sitlani CM; Department of Medicine, University of Washington, Seattle, Washington, United States of America.
Rice KM; Department of Biostatistics, University of Washington, Seattle, Washington, United States of America.
Maitland-van der Zee AH; Respiratory Medicine/Pediatric Respiratory Medicine, AMC, Amsterdam, the Netherlands.
Wadelius M; Medical School, University of Liverpool, Liverpool, United Kingdom.
Morris AP; Department of Biostatistics, University of Liverpool, Liverpool, United Kingdom.
Pirmohamed M; MRC Centre for Drug Safety Science, Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, United Kingdom.
Palmer CAN; Division of Molecular and Clinical Medicine, University of Dundee, Dundee, United Kingdom.
Psaty BM; Department of Medicine, University of Washington, Seattle, Washington, United States of America.
Alfirevic A; MRC Centre for Drug Safety Science, Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, United Kingdom.; Pokaż więcej
Corporate Authors:: PREDICTION-ADR Consortium and EUDRAGENE
Źródło:: PloS one [PLoS One] 2019 Jun 26; Vol. 14 (6), pp. e0218115. Date of Electronic Publication: 2019 Jun 26 (Print Publication: 2019).
Typ publikacji:: Journal Article; Meta-Analysis; Research Support, American Recovery and Reinvestment Act; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Systematic Review
MeSH Terms:: Muscle, Skeletal*/metabolism
Muscle, Skeletal*/pathology
Rhabdomyolysis*/chemically induced
Rhabdomyolysis*/genetics
Rhabdomyolysis*/metabolism
Rhabdomyolysis*/pathology
Whole Genome Sequencing*
Hydroxymethylglutaryl-CoA Reductase Inhibitors/*adverse effects
Genome-Wide Association Study ; High-Throughput Nucleotide Sequencing ; Humans ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use

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Tytuł:: Genetic overlap between endometriosis and endometrial cancer: evidence from cross-disease genetic correlation and GWAS meta-analyses.
Autorzy:: Painter JN; Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
O'Mara TA; Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
Morris AP; Wellcome Trust for Human Genetics, University of Oxford, Oxford, UK.; Department of Biostatistics, University of Liverpool, Liverpool, UK.
Cheng THT; Wellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre, University of Oxford, Oxford, UK.
Gorman M; Wellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre, University of Oxford, Oxford, UK.
Martin L; Wellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre, University of Oxford, Oxford, UK.
Hodson S; Department of Clinical Genetics, St George's, University of London, London, UK.
Jones A; Wellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre, University of Oxford, Oxford, UK.
Martin NG; Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
Gordon S; Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
Henders AK; Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia.
Attia J; Hunter Medical Research Institute, John Hunter Hospital, Newcastle, New South Wales, Australia.; Centre for Clinical Epidemiology and Biostatistics, School of Medicine and Public Health, University of Newcastle, Callaghan, New South Wales, Australia.
McEvoy M; Centre for Clinical Epidemiology and Biostatistics, School of Medicine and Public Health, University of Newcastle, Callaghan, New South Wales, Australia.
Holliday EG; Hunter Medical Research Institute, John Hunter Hospital, Newcastle, New South Wales, Australia.; Centre for Clinical Epidemiology and Biostatistics, School of Medicine and Public Health, University of Newcastle, Callaghan, New South Wales, Australia.
Scott RJ; Division of Molecular Medicine, Pathology North, John Hunter Hospital, Newcastle, New South Wales, Australia.; Discipline of Medical Genetics, School of Biomedical Sciences and Pharmacy, Faculty of Health, University of Newcastle, Callaghan, New South Wales, Australia.
Webb PM; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
Fasching PA; Department of Gynaecology and Obstetrics, University Hospital Erlangen, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen, Germany.; David Geffen School of Medicine, Department of Medicine Division of Hematology and Oncology, University of California at Los Angeles, Los Angeles, California.
Beckmann MW; Department of Gynaecology and Obstetrics, University Hospital Erlangen, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen, Germany.
Ekici AB; Institute of Human Genetics, University Hospital Erlangen, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen, Germany.
Hein A; Department of Gynaecology and Obstetrics, University Hospital Erlangen, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen, Germany.
Rübner M; Department of Gynaecology and Obstetrics, University Hospital Erlangen, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen, Germany.
Hall P; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Czene K; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Dörk T; Gynaecology Research Unit, Hannover Medical School, Hannover, Germany.
Dürst M; Department of Gynaecology, Jena University Hospital - Friedrich Schiller University, Jena, Germany.
Hillemanns P; Gynaecology Research Unit, Hannover Medical School, Hannover, Germany.
Runnebaum I; Department of Gynaecology, Jena University Hospital - Friedrich Schiller University, Jena, Germany.
Lambrechts D; VIB Center for Cancer Biology, VIB, Leuven, Belgium.; Laboratory for Translational Genetics, Department of Human Genetics, University of Leuven, Leuven, Belgium.
Amant F; Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, University Hospitals KU Leuven, University of Leuven, Leuven, Belgium.
Annibali D; Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, University Hospitals KU Leuven, University of Leuven, Leuven, Belgium.
Depreeuw J; Laboratory for Translational Genetics, Department of Human Genetics, University of Leuven, Leuven, Belgium.; Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, University Hospitals KU Leuven, University of Leuven, Leuven, Belgium.; Vesalius Research Center, VIB, Leuven, Belgium.
Vanderstichele A; Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, University Hospitals KU Leuven, University of Leuven, Leuven, Belgium.
Goode EL; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota.
Cunningham JM; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota.
Dowdy SC; Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Mayo Clinic, Rochester, Minnesota.
Winham SJ; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota.
Trovik J; Centre for Cancerbiomarkers, Department of Clinical Science, University of Bergen, Bergen, Norway.; Department of Obstetrics and Gynecology, Haukeland University Hospital, Bergen, Norway.
Hoivik E; Centre for Cancerbiomarkers, Department of Clinical Science, University of Bergen, Bergen, Norway.; Department of Obstetrics and Gynecology, Haukeland University Hospital, Bergen, Norway.
Werner HMJ; Centre for Cancerbiomarkers, Department of Clinical Science, University of Bergen, Bergen, Norway.; Department of Obstetrics and Gynecology, Haukeland University Hospital, Bergen, Norway.
Krakstad C; Centre for Cancerbiomarkers, Department of Clinical Science, University of Bergen, Bergen, Norway.; Department of Obstetrics and Gynecology, Haukeland University Hospital, Bergen, Norway.
Ashton K; Hunter Medical Research Institute, John Hunter Hospital, Newcastle, New South Wales, Australia.; Discipline of Medical Genetics, School of Biomedical Sciences and Pharmacy, Faculty of Health, University of Newcastle, Callaghan, New South Wales, Australia.; Centre for Information Based Medicine, University of Newcastle, Callaghan, New South Wales, Australia.
Otton G; School of Medicine and Public Health, University of Newcastle, Callaghan, New South Wales, Australia.
Proietto T; School of Medicine and Public Health, University of Newcastle, Callaghan, New South Wales, Australia.
Tham E; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.; Clinical Genetics, Karolinska Institutet, Stockholm, Sweden.
Mints M; Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.
Ahmed S; Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, UK.
Healey CS; Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, UK.
Shah M; Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, UK.
Pharoah PDP; Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, UK.; Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, UK.
Dunning AM; Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, UK.
Dennis J; Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, UK.
Bolla MK; Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, UK.
Michailidou K; Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, UK.; Department of Electron Microscopy/Molecular Pathology, The Cyprus Institute of Neurology and Genetics, Nicosia, Cyprus.
Wang Q; Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, UK.
Tyrer JP; Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, UK.
Hopper JL; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia.
Peto J; Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK.
Swerdlow AJ; Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK.; Division of Breast Cancer Research, The Institute of Cancer Research, London, UK.
Burwinkel B; Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany.; Molecular Epidemiology Group, C080, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Brenner H; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Division of Preventive Oncology, German Cancer Research Center (DKFZ), National Center for Tumor Diseases (NCT), Heidelberg, Germany.; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
Meindl A; Division of Gynaecology and Obstetrics, Technische Universität München, Munich, Germany.
Brauch H; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.; Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany.; University of Tübingen, Tübingen, Germany.
Lindblom A; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.
Chang-Claude J; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Research Group Genetic Cancer Epidemiology, University Cancer Center Hamburg (UCCH), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Couch FJ; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota.
Giles GG; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia.; Cancer Epidemiology & Intelligence Division, Cancer Council Victoria, Melbourne, Victoria, Australia.
Kristensen VN; Department of Cancer Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, Oslo, Norway.; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.; Department of Clinical Molecular Biology, Oslo University Hospital, University of Oslo, Oslo, Norway.
Cox A; Department of Oncology and Metabolism, Sheffield Institute for Nucleic Acids (SInFoNiA), University of Sheffield, Sheffield, UK.
Zondervan KT; Department of Obstetrics & Gynaecology, Endometriosis CaRe Centre, Nuffield, University of Oxford, Oxford, UK.
Nyholt DR; Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.; Institute of Health and Biomedical Innovation and School of Biomedical Science, Queensland University of Technology, Brisbane, Queensland, Australia.
MacGregor S; Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
Montgomery GW; Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.; Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia.
Tomlinson I; Wellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre, University of Oxford, Oxford, UK.
Easton DF; Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, UK.; Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, UK.
Thompson DJ; Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, UK.
Spurdle AB; Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.; Pokaż więcej
Źródło:: Cancer medicine [Cancer Med] 2018 May; Vol. 7 (5), pp. 1978-1987. Date of Electronic Publication: 2018 Apr 02.
Typ publikacji:: Journal Article; Meta-Analysis; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:: Endometrial Neoplasms/*genetics
Endometriosis/*genetics
Genetic Predisposition to Disease/*genetics
Receptor-Like Protein Tyrosine Phosphatases, Class 2/*genetics
Australia/epidemiology ; Endometrial Neoplasms/epidemiology ; Endometriosis/epidemiology ; Endometrium/pathology ; Female ; Genome-Wide Association Study ; Humans ; Polymorphism, Single Nucleotide/genetics ; STAT3 Transcription Factor/metabolism

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Skocz do pozycji: 11.

Tytuł:: A dual-application poly (dl-lactic-co-glycolic) acid (PLGA)-chitosan composite scaffold for potential use in bone tissue engineering.
Autorzy:: Boukari Y; a School of Pharmacy , The University of Nottingham Malaysia Campus , Semenyih , Malaysia.
Qutachi O; b School of Pharmacy , The University of Nottingham, Park Campus , Nottingham , UK.
Scurr DJ; b School of Pharmacy , The University of Nottingham, Park Campus , Nottingham , UK.
Morris AP; a School of Pharmacy , The University of Nottingham Malaysia Campus , Semenyih , Malaysia.
Doughty SW; c Penang Medical College , George Town , Malaysia.
Billa N; a School of Pharmacy , The University of Nottingham Malaysia Campus , Semenyih , Malaysia.; Pokaż więcej
Źródło:: Journal of biomaterials science. Polymer edition [J Biomater Sci Polym Ed] 2017 Nov; Vol. 28 (16), pp. 1966-1983. Date of Electronic Publication: 2017 Aug 17.
Typ publikacji:: Journal Article
MeSH Terms:: Tissue Engineering*
Biocompatible Materials/*chemistry
Biocompatible Materials/*pharmacology
Bone and Bones/*cytology
Chitosan/*chemistry
Lactic Acid/*chemistry
Polyglycolic Acid/*chemistry
Tissue Scaffolds/*chemistry
Biocompatible Materials/metabolism ; Bone Morphogenetic Protein 2/metabolism ; Calcification, Physiologic/drug effects ; Cell Proliferation/drug effects ; Humans ; Injections ; Kinetics ; Mesenchymal Stem Cells/cytology ; Mesenchymal Stem Cells/drug effects ; Microspheres ; Osteocalcin/metabolism ; Polylactic Acid-Polyglycolic Acid Copolymer ; Serum Albumin, Bovine/metabolism

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Skocz do pozycji: 12.

Tytuł:: Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis.
Autorzy:: Wheeler E; Department of Human Genetics, Wellcome Trust Sanger Institute, Genome Campus, Hinxton, Cambridge, United Kingdom.
Leong A; Division of General Internal Medicine, Massachusetts General Hospital, Boston, MA, United States of America.; Harvard Medical School, Boston, MA, United States of America.
Liu CT; Department of Biostatistics, Boston University School of Public Health, Boston, MA, United States of America.
Hivert MF; Department of Population Medicine, Harvard Medical School, Harvard Pilgrim Health Care Institute, Boston, MA, United States of America.; Massachusetts General Hospital, Boston, MA, United States of America.
Strawbridge RJ; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.; Centre for Molecular Medicine, Karolinska Universitetsjukhuset, Solna, Sweden.
Podmore C; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom.; Department of Internal Medicine, Lausanne University Hospital (CHUV), Lausanne, Switzerland.
Li M; Department of Epidemiology, The Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States of America.; Division of Nephrology, University of Utah, Salt Lake City, UT, United States of America.; Department of Human Genetics, University of Utah, Salt Lake City, UT, United States of America.
Yao J; Institute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, United States of America.
Sim X; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.
Hong J; Department of Biostatistics, Boston University School of Public Health, Boston, MA, United States of America.
Chu AY; National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, MA, United States of America.; Division of Preventive Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States of America.
Zhang W; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom.; Department of Cardiology, Ealing Hospital NHS Trust, Southall, Middlesex, United Kingdom.
Wang X; Life Sciences Institute, National University of Singapore, Singapore, Singapore.
Chen P; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.; Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, AZ, United States of America.; Key Laboratory of Pathobiology, Ministry of Education, Jilin University, Changchun, Jilin, China.; College of Basic Medical Sciences, Jilin University, Changchun, Jilin, China.
Maruthur NM; Department of Epidemiology, The Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States of America.; Division of General Internal Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, United States of America.; Welch Center for Prevention, Epidemiology and Clinical Research, The Johns Hopkins University, Baltimore, MD, United States of America.
Porneala BC; Division of General Internal Medicine, Massachusetts General Hospital, Boston, MA, United States of America.
Sharp SJ; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom.
Jia Y; Institute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, United States of America.
Kabagambe EK; Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, United States of America.
Chang LC; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.
Chen WM; University of Virginia Center for Public Health Genomics, Charlottesville, VA, United States of America.
Elks CE; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom.; Personalised Healthcare & Biomarkers, Innovative Medicines and Early Development Biotech Unit, AstraZeneca, Cambridge, United Kingdom.
Evans DS; California Pacific Medical Center Research Institute, San Francisco, CA, United States of America.
Fan Q; Centre for Quantitative Medicine, Duke-NUS Medical School, Singapore, Singapore.
Giulianini F; Division of Preventive Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States of America.
Go MJ; Division of Structural and Functional Genomics, Center for Genome Science, Korean National Institute of Health, Osong, Chungchungbuk-do, South Korea.
Hottenga JJ; Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
Hu Y; The Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, University of the Chinese Academy of Sciences, Shanghai, People's Republic of China.
Jackson AU; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, United States of America.
Kanoni S; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.
Kim YJ; Division of Structural and Functional Genomics, Center for Genome Science, Korean National Institute of Health, Osong, Chungchungbuk-do, South Korea.
Kleber ME; Vth Department of Medicine, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.
Ladenvall C; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.; Lund University Diabetes Centre, Lund University, Lund, Sweden.
Lecoeur C; University of Lille, CNRS, Institut Pasteur of Lille, UMR 8199-EGID, Lille, France.
Lim SH; Singapore Eye Research Institute, The Academia Level 6, Discovery Tower, Singapore, Singapore.
Lu Y; The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, NY, United States of America.; The Genetics of Obesity and Related Metabolic Traits Program, The Icahn School of Medicine at Mount Sinai, New York, NY, United States of America.
Mahajan A; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.
Marzi C; Institute of Epidemiology II, Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; German Center for Diabetes Research (DZD e.V.), Partner Munich, Munich, Germany.
Nalls MA; Data Tecnica International, Glen Echo, MD, United States of America.; Laboratory of Neurogenetics, National Institute on Aging, Bethesda, MD, United States of America.
Navarro P; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland.
Nolte IM; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.
Rose LM; Division of Preventive Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States of America.
Rybin DV; Department of Biostatistics, Boston University School of Public Health, Boston, MA, United States of America.; Data Coordinating Center, Boston University School of Public Health, Boston, MA, United States of America.
Sanna S; Istituto di Ricerca Genetica e Biomedica (IRGB), CNR, Monserrato, Italy.
Shi Y; Singapore Eye Research Institute, The Academia Level 6, Discovery Tower, Singapore, Singapore.
Stram DO; Department of Preventive Medicine, University of Southern California, Los Angeles, CA, United States of America.
Takeuchi F; Department of Gene Diagnostics and Therapeutics, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan.
Tan SP; Singapore Eye Research Institute, The Academia Level 6, Discovery Tower, Singapore, Singapore.
van der Most PJ; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.
Van Vliet-Ostaptchouk JV; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.; Department of Endocrinology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.
Wong A; MRC Unit for Lifelong Health & Ageing, London, United Kingdom.
Yengo L; University of Lille, CNRS, Institut Pasteur of Lille, UMR 8199-EGID, Lille, France.
Zhao W; Singapore Eye Research Institute, The Academia Level 6, Discovery Tower, Singapore, Singapore.
Goel A; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom.
Martinez Larrad MT; Spanish Biomedical Research Centre in Diabetes and Associated Metabolic Disorders (CIBERDEM), Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Madrid, Spain.
Radke D; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.
Salo P; National Institute for Health and Welfare (THL), Helsinki, Finland.; University of Helsinki, Institute for Molecular Medicine, Finland (FIMM) and Diabetes and Obesity Research Program, Helsinki, Finland.
Tanaka T; Translational Gerontology Branch, National Institute on Aging, Baltimore, MD, United States of America.
van Iperen EPA; Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands.; Durrer Center for Cardiogenetic Research, ICIN-Netherlands Heart Institute, Utrecht, Netherlands.
Abecasis G; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, United States of America.
Afaq S; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom.
Alizadeh BZ; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.
Bertoni AG; Department of Epidemiology and Prevention, Wake Forest School of Medicine, Winston-Salem, NC, United States of America.
Bonnefond A; University of Lille, CNRS, Institut Pasteur of Lille, UMR 8199-EGID, Lille, France.
Böttcher Y; Integrated Research and Treatment (IFB) Center Adiposity Diseases, University of Leipzig, Leipzig, Germany.
Bottinger EP; The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, NY, United States of America.
Campbell H; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland.
Carlson OD; Laboratory of Clinical Investigation, National Institute on Aging, Baltimore, MD, United States of America.
Chen CH; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.; School of Chinese Medicine, China Medical University, Taichung City, Taiwan.
Cho YS; Division of Structural and Functional Genomics, Center for Genome Science, Korean National Institute of Health, Osong, Chungchungbuk-do, South Korea.; Department of Biomedical Science, Hallym University, Chuncheon, Gangwon-do, South Korea.
Garvey WT; Department of Nutrition Sciences, University of Alabama at Birmingham and the Birmingham Veterans Affairs Medical Center, Birmingham, AL, United States of America.
Gieger C; Institute of Epidemiology II, Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.
Goodarzi MO; Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, United States of America.
Grallert H; Institute of Epidemiology II, Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; German Center for Diabetes Research (DZD e.V.), Partner Munich, Munich, Germany.
Hamsten A; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.; Centre for Molecular Medicine, Karolinska Universitetsjukhuset, Solna, Sweden.
Hartman CA; Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.
Herder C; Institute for Clinical Diabetology, German Diabetes Center, Leibniz Institute for Diabetes Research at Heinrich Heine University Düsseldorf, Düsseldorf, Germany.; German Center for Diabetes Research (DZD), München-Neuherberg, Germany.
Hsiung CA; Division of Endocrinology, Diabetes, Metabolism, Department of Internal Medicine, Wexner Medical Center, The Ohio State University, Columbus, OH, United States of America.
Huang J; Boston VA Research Institute, Inc., Boston, MA, United States of America.
Igase M; Department of Geriatric Medicine, Ehime University Graduate School of Medicine, Ehime, Japan.
Isono M; Department of Gene Diagnostics and Therapeutics, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan.
Katsuya T; Department of Clinical Gene Therapy, Osaka University Graduate School of Medicine, Suita, Japan.; Department of Geriatric Medicine and Nephrology, Osaka University Graduate School of Medicine, Suita, Japan.
Khor CC; Genome Institute of Singapore, Agency for Science Technology and Research, Singapore, Singapore.
Kiess W; Center of Pediatric Research, University Hospital for Children & Adolescents, Dept. of Women's & Child Health, University of Leipzig, Leipzig, Germany.; LIFE Child, LIFE Leipzig Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany.
Kohara K; Faculty of Collaborative Regional Innovation, Ehime University, Ehime, Japan.
Kovacs P; Integrated Research and Treatment (IFB) Center Adiposity Diseases, University of Leipzig, Leipzig, Germany.
Lee J; Division of Structural and Functional Genomics, Center for Genome Science, Korean National Institute of Health, Osong, Chungchungbuk-do, South Korea.
Lee WJ; Department of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan.
Lehne B; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom.
Li H; The Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, University of the Chinese Academy of Sciences, Shanghai, People's Republic of China.
Liu J; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.; Genome Institute of Singapore, Agency for Science Technology and Research, Singapore, Singapore.
Lobbens S; University of Lille, CNRS, Institut Pasteur of Lille, UMR 8199-EGID, Lille, France.
Luan J; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom.
Lyssenko V; Lund University Diabetes Centre, Lund University, Lund, Sweden.
Meitinger T; Institute of Human Genetics, Technische Universität München, Munich, Germany.; Institute of Human Genetics, Helmholtz Zentrum München, Neuherberg, Germany.; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.
Miki T; Department of Geriatric Medicine, Ehime University Graduate School of Medicine, Ehime, Japan.
Miljkovic I; Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, United States of America.
Moon S; Division of Structural and Functional Genomics, Center for Genome Science, Korean National Institute of Health, Osong, Chungchungbuk-do, South Korea.
Mulas A; Istituto di Ricerca Genetica e Biomedica (IRGB), CNR, Monserrato, Italy.
Müller G; Center for Evidence-based Healthcare, University Hospital and Medical Faculty Carl Gustav Carus, Dresden, Germany.
Müller-Nurasyid M; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Department of Medicine I, University Hospital Grosshadern, Ludwig-Maximilians-Universität, Munich, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany.
Nagaraja R; Laboratory of Genetics, National Institute on Aging, Baltimore, MD, United States of America.
Nauck M; Institute for Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany.
Pankow JS; Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN, United States of America.
Polasek O; University of Split, Split, Croatia.; Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom.
Prokopenko I; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom.; Department of Genomics of Common Disease, School of Public Health, Imperial College London, London, United Kingdom.
Ramos PS; Department of Medicine, Medical University of South Carolina, Charleston, SC, United States of America.
Rasmussen-Torvik L; Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, United States of America.
Rathmann W; German Center for Diabetes Research (DZD), München-Neuherberg, Germany.
Rich SS; Center for Public Health Genomics, University of Virginia School of Medicine, Charlottesville, VA, United States of America.
Robertson NR; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom.; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
Roden M; Institute for Clinical Diabetology, German Diabetes Center, Leibniz Institute for Diabetes Research at Heinrich Heine University Düsseldorf, Düsseldorf, Germany.; German Center for Diabetes Research (DZD), München-Neuherberg, Germany.; Department of Endocrinology and Diabetology, University Hospital Düsseldorf, Düsseldorf, Germany.
Roussel R; INSERM, UMR_S 1138, Centre de Recherche des Cordelier, Paris, France.; Université Paris Diderot, Sorbonne Paris Cité, UFR de Médecine, Paris, France.; Assistance Publique Hôpitaux de Paris, Bichat Hospital, DHU FIRE, Department of Diabetology, Endocrinology and Nutrition, Paris, France.
Rudan I; University of Edinburgh, Edinburgh, United Kingdom.
Scott RA; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom.
Scott WR; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom.; Department of Cardiology, Ealing Hospital NHS Trust, Southall, Middlesex, United Kingdom.
Sennblad B; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.; Centre for Molecular Medicine, Karolinska Universitetsjukhuset, Solna, Sweden.; Science for life laboratory, Karolinska Institutet, Solna, Sweden.
Siscovick DS; The New York Academy of Medicine, New York, NY, United States of America.
Strauch K; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Medical Informatics, Biometry and Epidemiology, Ludwig-Maximilians-Universität, Munich, Germany.
Sun L; The Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, University of the Chinese Academy of Sciences, Shanghai, People's Republic of China.
Swertz M; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.
Tajuddin SM; Health Disparities Unit, National Institute on Aging, National Institutes of Health, Baltimore, MD, United States of America.
Taylor KD; Institute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, United States of America.
Teo YY; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.; Life Sciences Institute, National University of Singapore, Singapore, Singapore.; Genome Institute of Singapore, Agency for Science Technology and Research, Singapore, Singapore.; Department of Statistics and Applied Probability, National University of Singapore, Singapore, Singapore.; NUS Graduate School for Integrative Science and Engineering, National University of Singapore, Singapore, Singapore.
Tham YC; Singapore Eye Research Institute, The Academia Level 6, Discovery Tower, Singapore, Singapore.
Tönjes A; Department of Medicine; University of Leipzig, Leipzig, Germany.
Wareham NJ; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom.
Willemsen G; Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
Wilsgaard T; Dept of Community Medicine, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway.
Hingorani AD; Institute of Cardiovascular Science, University College London, London, United Kingdom.
Egan J; Laboratory of Clinical Investigation, National Institute on Aging, Baltimore, MD, United States of America.
Ferrucci L; Laboratory of Clinical Investigation, National Institute on Aging, Baltimore, MD, United States of America.
Hovingh GK; Department of Vascular Medicine, Academic Medical Center, Amsterdam, Netherlands.
Jula A; National Institute for Health and Welfare (THL), Helsinki, Finland.
Kivimaki M; Department of Epidemiology and Public Health, University College London, London, United Kingdom.
Kumari M; Department of Epidemiology and Public Health, University College London, London, United Kingdom.; Institute for Social and Economic Research, University of Essex, Colchester, United Kingdom.
Njølstad I; Dept of Community Medicine, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway.
Palmer CNA; Pat Macpherson Centre for Pharmacogenetics and Pharmacogenomics, Medical Research Institute, Ninewells Hospital and Medical School, Dundee, United Kingdom.
Serrano Ríos M; Spanish Biomedical Research Centre in Diabetes and Associated Metabolic Disorders (CIBERDEM), Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Madrid, Spain.
Stumvoll M; Department of Medicine; University of Leipzig, Leipzig, Germany.
Watkins H; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom.
Aung T; Singapore Eye Research Institute, The Academia Level 6, Discovery Tower, Singapore, Singapore.; Ophthalmology and Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Singapore National Eye Centre, Singapore, Singapore.
Blüher M; Department of Medicine; University of Leipzig, Leipzig, Germany.
Boehnke M; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, United States of America.
Boomsma DI; Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
Bornstein SR; Dept of Medicine III, University of Dresden, Medical Faculty Carl Gustav Carus, Dresden, Germany.
Chambers JC; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom.; Department of Cardiology, Ealing Hospital NHS Trust, Southall, Middlesex, United Kingdom.; Imperial College Healthcare NHS Trust, London, United Kingdom.
Chasman DI; Division of Preventive Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States of America.; Division of Genetics, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States of America.; Broad Institute of MIT and Harvard, Cambridge, MA, United States of America.
Chen YI; Institute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, United States of America.
Chen YT; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.
Cheng CY; Singapore Eye Research Institute, The Academia Level 6, Discovery Tower, Singapore, Singapore.; Ophthalmology and Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Singapore National Eye Centre, Singapore, Singapore.
Cucca F; Istituto di Ricerca Genetica e Biomedica (IRGB), CNR, Monserrato, Italy.; Dipartimento di Scienze Biomediche, Università di Sassari, Italy.
de Geus EJC; Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
Deloukas P; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.; Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders (PACER-HD), King Abdulaziz University, Jeddah, Saudi Arabia.
Evans MK; Health Disparities Unit, National Institute on Aging, National Institutes of Health, Baltimore, MD, United States of America.
Fornage M; Brown Foundation Institute of Molecular Medicine, Division of Epidemiology, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, United States of America.
Friedlander Y; Braun School of Public Health, Hebrew University-Hadassah Medical Center, Jerusalem, Israel.
Froguel P; Department of Genomics of Common Disease, School of Public Health, Imperial College London, London, United Kingdom.; CNRS 8199-Lille University, France.
Groop L; Lund University Diabetes Centre, Lund University, Lund, Sweden.; Finnish Institute for Molecular Medicine (FIMM), Helsinki, Finland.
Gross MD; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN, United States of America.
Harris TB; National Institute on Aging, Bethesda, MD, United States of America.
Hayward C; Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom.
Heng CK; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Khoo Teck Puat-National University Children's Medical Institute, National University Health System, Singapore, Singapore.
Ingelsson E; Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.; Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, United States of America.
Kato N; Department of Gene Diagnostics and Therapeutics, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan.
Kim BJ; Division of Structural and Functional Genomics, Center for Genome Science, Korean National Institute of Health, Osong, Chungchungbuk-do, South Korea.
Koh WP; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.; Duke-NUS Medical School Singapore, Singapore.
Kooner JS; Department of Cardiology, Ealing Hospital NHS Trust, Southall, Middlesex, United Kingdom.; Imperial College Healthcare NHS Trust, London, United Kingdom.; National Heart and Lung Institute, Imperial College London, Hammersmith Hospital Campus, London, United Kingdom.
Körner A; Center of Pediatric Research, University Hospital for Children & Adolescents, Dept. of Women's & Child Health, University of Leipzig, Leipzig, Germany.; LIFE Child, LIFE Leipzig Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany.
Kuh D; MRC Unit for Lifelong Health & Ageing, London, United Kingdom.
Kuusisto J; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland.
Laakso M; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland.
Lin X; The Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, University of the Chinese Academy of Sciences, Shanghai, People's Republic of China.
Liu Y; Department of Epidemiology and Prevention, Division of Public Health Sciences, Wake Forest University, Winston-Salem, NC, United States of America.
Loos RJF; The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, NY, United States of America.; The Genetics of Obesity and Related Metabolic Traits Program, The Icahn School of Medicine at Mount Sinai, New York, NY, United States of America.; The Mindich Child Health Development Institute, The Icahn School of Medicine at Mount Sinai, New York, NY, United States of America.
Magnusson PKE; Department of Medical Epidemiology and Biostatistics, Karolinska Insitutet, Stockholm, Sweden.
März W; Vth Department of Medicine, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.; Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria.; Synlab Academy, Synlab Services GmbH, Mannheim, Germany.
McCarthy MI; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom.; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, United Kingdom.
Oldehinkel AJ; Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.
Ong KK; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom.
Pedersen NL; Department of Medical Epidemiology and Biostatistics, Karolinska Insitutet, Stockholm, Sweden.
Pereira MA; Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN, United States of America.
Peters A; Institute of Epidemiology II, Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.
Ridker PM; Division of Preventive Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States of America.; Division of Cardiovascular Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States of America.
Sabanayagam C; Singapore Eye Research Institute, The Academia Level 6, Discovery Tower, Singapore, Singapore.; Ophthalmology and Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore.
Sale M; Center for Public Health Genomics, University of Virginia School of Medicine, Charlottesville, VA, United States of America.
Saleheen D; Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA, United States of America.; Center for Non-Communicable Diseases, Karachi, Pakistan.
Saltevo J; Department of Medicine, Central Hospital, Central Finland, Jyväskylä, Finland.
Schwarz PE; Dept of Medicine III, University of Dresden, Medical Faculty Carl Gustav Carus, Dresden, Germany.
Sheu WHH; Division of Endocrine and Metabolism, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.; School of Medicine, National Yang-Ming University, Taipei, Taiwan.; School of Medicine, National Defense Medical Center, Taipei, Taiwan.
Snieder H; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.
Spector TD; Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom.
Tabara Y; Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Tuomilehto J; Chronic Disease Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland.; Dasman Diabetes Institute, Dasman, Kuwait.; Centre for Vascular Prevention, Danube-University Krems, Krems, Austria.; Saudi Diabetes Research Group, King Abdulaziz University, Fahd Medical Research Center, Jeddah, Saudi Arabia.
van Dam RM; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.
Wilson JG; Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, MS, United States of America.
Wilson JF; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland.; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland.
Wolffenbuttel BHR; Department of Endocrinology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.
Wong TY; Singapore Eye Research Institute, The Academia Level 6, Discovery Tower, Singapore, Singapore.; Ophthalmology and Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Singapore National Eye Centre, Singapore, Singapore.
Wu JY; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.; School of Chinese Medicine, China Medical University, Taichung City, Taiwan.
Yuan JM; Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, United States of America.; Division of Cancer Control and Population Sciences,University of Pittsburgh Cancer Institute, Pittsburgh, PA, United States of America.
Zonderman AB; Laboratory of Epidemiology & Population Sciences, National Institute on Aging, National Institutes of Health, Baltimore, MD, United States of America.
Soranzo N; Department of Human Genetics, Wellcome Trust Sanger Institute, Genome Campus, Hinxton, Cambridge, United Kingdom.; Department of Haematology, University of Cambridge, Cambridge, United Kingdom.; The National Institute for Health Research Blood and Transplant Unit (NIHR BTRU) in Donor Health and Genomics at the University of Cambridge, United Kingdom.
Guo X; Institute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, United States of America.
Roberts DJ; Biomedical Research Centre Oxford Haematology Theme and Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Headley Way, Headington, Oxford, United Kingdom.; NHS Blood and Transplant, Headington, Oxford, United Kingdom.
Florez JC; Harvard Medical School, Boston, MA, United States of America.; Diabetes Unit and Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA, United States of America.; Programs in Metabolism and Medical & Population Genetics, Broad Institute, Cambridge, MA, United States of America.
Sladek R; Department of Medicine, McGill University, Montreal, Quebec, Canada.
Dupuis J; Department of Biostatistics, Boston University School of Public Health, Boston, MA, United States of America.; National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, MA, United States of America.
Morris AP; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.; Department of Biostatistics, University of Liverpool, Liverpool, United Kingdom.
Tai ES; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.; Duke-NUS Medical School Singapore, Singapore.; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Selvin E; Department of Epidemiology, The Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States of America.; Division of General Internal Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, United States of America.; Welch Center for Prevention, Epidemiology and Clinical Research, The Johns Hopkins University, Baltimore, MD, United States of America.
Rotter JI; Institute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, United States of America.
Langenberg C; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom.
Barroso I; Department of Human Genetics, Wellcome Trust Sanger Institute, Genome Campus, Hinxton, Cambridge, United Kingdom.; Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom.
Meigs JB; Division of General Internal Medicine, Massachusetts General Hospital, Boston, MA, United States of America.; Harvard Medical School, Boston, MA, United States of America.; Programs in Metabolism and Medical & Population Genetics, Broad Institute, Cambridge, MA, United States of America.; Pokaż więcej
Corporate Authors:: EPIC-CVD Consortium
EPIC-InterAct Consortium
Lifelines Cohort Study
Źródło:: PLoS medicine [PLoS Med] 2017 Sep 12; Vol. 14 (9), pp. e1002383. Date of Electronic Publication: 2017 Sep 12 (Print Publication: 2017).
Typ publikacji:: Journal Article; Meta-Analysis
MeSH Terms:: Genetic Variation*
Genome-Wide Association Study*
Diabetes Mellitus, Type 2/*diagnosis
Diabetes Mellitus, Type 2/*genetics
Glycated Hemoglobin/*genetics
Diabetes Mellitus, Type 2/epidemiology ; Glycated Hemoglobin/metabolism ; Humans ; Phenotype ; Risk

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Skocz do pozycji: 13.

Tytuł:: Ranking and characterization of established BMI and lipid associated loci as candidates for gene-environment interactions.
Autorzy:: Shungin D; Department of Clinical Sciences, Genetic & Molecular Epidemiology Unit, Lund University Diabetes Centre, Skåne University Hospital, Malmö, Sweden.; Department of Odontology, Umeå University, Umeå, Sweden.; Department of Public Health and Clinical Medicine, Unit of Medicine, Umeå University, Umeå, Sweden.; Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, MA, United States of America.
Deng WQ; Department of Statistical Sciences, University of Toronto, Toronto, Canada.
Varga TV; Department of Clinical Sciences, Genetic & Molecular Epidemiology Unit, Lund University Diabetes Centre, Skåne University Hospital, Malmö, Sweden.; Novo Nordisk Foundation Center for Protein Research, Translational Disease Systems Biology Group, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Department of Health Sciences, Exercise Physiology Group, Lund University, Lund, Sweden.
Luan J; MRC Epidemiology Unit, University of Cambridge, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, United Kingdom.
Mihailov E; Estonian Genome Center, University of Tartu, Tartu, Estonia.
Metspalu A; Estonian Genome Center, University of Tartu, Tartu, Estonia.; Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia.
Morris AP; Estonian Genome Center, University of Tartu, Tartu, Estonia.; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.; Department of Biostatistics, University of Liverpool, Liverpool, United Kingdom.
Forouhi NG; MRC Epidemiology Unit, University of Cambridge, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, United Kingdom.
Lindgren C; Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, MA, United States of America.; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.
Magnusson PKE; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Pedersen NL; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Hallmans G; Department of Biobank Research, Umeå University, Umeå, Sweden.
Chu AY; Harvard Medical School, Boston, MA, United States of America.
Justice AE; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America.
Graff M; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America.
Winkler TW; Department of Genetic Epidemiology, University of Regensburg, Regensburg, DE, Germany.
Rose LM; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, United States of America.
Langenberg C; MRC Epidemiology Unit, University of Cambridge, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, United Kingdom.; Department of Epidemiology and Public Health, UCL London, United Kingdom.
Cupples LA; Department of Biostatistics, Boston University School of Public Health, Boston, MA.; The NHLBI Framingham Heart Study, Framingham, MA.
Ridker PM; Harvard Medical School, Boston, MA, United States of America.; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, United States of America.
Wareham NJ; MRC Epidemiology Unit, University of Cambridge, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, United Kingdom.
Ong KK; MRC Epidemiology Unit, University of Cambridge, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, United Kingdom.
Loos RJF; The Genetics of Obesity and Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, NY.; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY.; The Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY.
Chasman DI; Harvard Medical School, Boston, MA, United States of America.; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, United States of America.
Ingelsson E; Science for Life Laboratory, Uppsala University, Uppsala, Sweden.; Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala, Sweden.; Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, United States of America.
Kilpeläinen TO; The Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Scott RA; MRC Epidemiology Unit, University of Cambridge, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, United Kingdom.
Mägi R; Estonian Genome Center, University of Tartu, Tartu, Estonia.; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.
Paré G; Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Canada.
Franks PW; Department of Clinical Sciences, Genetic & Molecular Epidemiology Unit, Lund University Diabetes Centre, Skåne University Hospital, Malmö, Sweden.; Department of Public Health and Clinical Medicine, Unit of Medicine, Umeå University, Umeå, Sweden.; Department of Nutrition, Harvard TH Chan School of Public Health, Boston, Massachusetts, United States of America.; Oxford Centre for Diabetes, Endocrinology & Metabolism, Radcliff Department of Medicine, University of Oxford, Oxford, United Kingdom.; Pokaż więcej
Corporate Authors:: GIANT Consortium
Źródło:: PLoS genetics [PLoS Genet] 2017 Jun 14; Vol. 13 (6), pp. e1006812. Date of Electronic Publication: 2017 Jun 14 (Print Publication: 2017).
Typ publikacji:: Journal Article; Meta-Analysis
MeSH Terms:: Gene-Environment Interaction*
Cholesterol, HDL/*genetics
Cholesterol, LDL/*genetics
Obesity/*genetics
Body Mass Index ; Cholesterol, HDL/blood ; Cholesterol, LDL/blood ; Female ; Genetic Heterogeneity ; Genetic Predisposition to Disease ; Genome-Wide Association Study ; Genotype ; Humans ; Male ; Obesity/blood ; Polymorphism, Single Nucleotide ; Quantitative Trait Loci/genetics ; Risk Factors ; Smoking/genetics ; White People/genetics

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Pełny tekst Szczegóły

Skocz do pozycji: 14.

Tytuł:: SurvivalGWAS_SV: software for the analysis of genome-wide association studies of imputed genotypes with "time-to-event" outcomes.
Autorzy:: Syed H; Department of Biostatistics, University of Liverpool, Liverpool, UK. .
Jorgensen AL; Department of Biostatistics, University of Liverpool, Liverpool, UK.
Morris AP; Department of Biostatistics, University of Liverpool, Liverpool, UK.; Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, UK.; Pokaż więcej
Źródło:: BMC bioinformatics [BMC Bioinformatics] 2017 May 19; Vol. 18 (1), pp. 265. Date of Electronic Publication: 2017 May 19.
Typ publikacji:: Journal Article
MeSH Terms:: Software*
Genome-Wide Association Study/*methods
Computer Simulation ; Genotype ; Humans ; Polymorphism, Single Nucleotide/genetics ; Proportional Hazards Models ; Time Factors

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Pełny tekst Szczegóły

Skocz do pozycji: 15.

Tytuł:: Mapping of 79 loci for 83 plasma protein biomarkers in cardiovascular disease.
Autorzy:: Folkersen L; Department of Systems Biology, Technical University of Denmark, Copenhagen, Denmark.; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.
Fauman E; Pfizer Worldwide Research & Development, Cambridge, Massachusetts, United States of America.
Sabater-Lleal M; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.
Strawbridge RJ; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.
Frånberg M; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.
Sennblad B; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.
Baldassarre D; Dipartimento di Scienze Farmacologiche e Biomolecolari, Università di Milano, Milan, Italy.; Centro Cardiologico Monzino, IRCCS, Milan, Italy.
Veglia F; Centro Cardiologico Monzino, IRCCS, Milan, Italy.
Humphries SE; British Heart Foundation Laboratories, University College of London, Department of Medicine, Rayne Building, London, United Kingdom.
Rauramaa R; Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.
de Faire U; Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, and Department of Cardiology, Karolinska University Hospital, Solna, Karolinska Institutet, Stockholm, Sweden.
Smit AJ; Department of Medicine, University Medical Center Groningen, Groningen, the Netherlands.
Giral P; Assistance Publique - Hopitaux de Paris; Service Endocrinologie-Metabolisme, Groupe Hôpitalier Pitie-Salpetriere, Unités de Prévention Cardiovasculaire, Paris, France.
Kurl S; Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio Campus, Kuopio, Finland.
Mannarino E; Internal Medicine, Angiology and Arteriosclerosis Diseases, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy.
Enroth S; Department of Immunology, Genetics and Pathology, Science for Life Laboratory Uppsala, Uppsala University, Uppsala, Sweden.
Johansson Å; Department of Immunology, Genetics and Pathology, Science for Life Laboratory Uppsala, Uppsala University, Uppsala, Sweden.
Enroth SB; Department of Internal Medicine, Uppsala University Hospital, Uppsala, Sweden.
Gustafsson S; Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
Lind L; Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
Lindgren C; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.
Morris AP; Department of Biostatistics, University of Liverpool, Liverpool, United Kingdom.
Giedraitis V; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.
Silveira A; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.
Franco-Cereceda A; Cardiothoracic Surgery Unit, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.
Tremoli E; Dipartimento di Scienze Farmacologiche e Biomolecolari, Università di Milano, Milan, Italy.; Centro Cardiologico Monzino, IRCCS, Milan, Italy.
Gyllensten U; Department of Immunology, Genetics and Pathology, Science for Life Laboratory Uppsala, Uppsala University, Uppsala, Sweden.
Ingelsson E; Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.; Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, California, United States of America.
Brunak S; Department of Systems Biology, Technical University of Denmark, Copenhagen, Denmark.
Eriksson P; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.
Ziemek D; Pfizer Worldwide Research & Development, Cambridge, Massachusetts, United States of America.
Hamsten A; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.
Mälarstig A; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.; Pfizer Worldwide Research and Development, Stockholm, Sweden.; Pokaż więcej
Corporate Authors:: IMPROVE study group
Źródło:: PLoS genetics [PLoS Genet] 2017 Apr 03; Vol. 13 (4), pp. e1006706. Date of Electronic Publication: 2017 Apr 03 (Print Publication: 2017).
Typ publikacji:: Journal Article; Multicenter Study; Observational Study
MeSH Terms:: Quantitative Trait Loci*
Biomarkers/*blood
Blood Proteins/*genetics
Cardiovascular Diseases/*blood
Cardiovascular Diseases/*genetics
Coronary Artery Disease/blood ; Coronary Artery Disease/genetics ; Female ; Genetic Predisposition to Disease ; Genome-Wide Association Study ; Humans ; Male

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Pełny tekst Szczegóły

Skocz do pozycji: 16.

Tytuł:: Admixture mapping in two Mexican samples identifies significant associations of locus ancestry with triglyceride levels in the BUD13/ZNF259/APOA5 region and fine mapping points to rs964184 as the main driver of the association signal.
Autorzy:: Parra EJ; Department of Anthropology, University of Toronto at Mississauga, Mississauga, ON, Canada.
Mazurek A; Department of Anthropology, University of Toronto at Mississauga, Mississauga, ON, Canada.
Gignoux CR; Department of Genetics, Stanford University, Stanford, CA, United States of America.
Sockell A; School of Medicine, Stanford University, Stanford, CA, United States of America.
Agostino M; Department of Anthropology, University of Toronto at Mississauga, Mississauga, ON, Canada.
Morris AP; Department of Biostatistics, University of Liverpool, Liverpool, United Kingdom.
Petty LE; Department of Epidemiology, Human Genetics & Environmental Sciences, University of Texas School of Public Health, Houston, TX, United States of America.
Hanis CL; Department of Epidemiology, Human Genetics & Environmental Sciences, University of Texas School of Public Health, Houston, TX, United States of America.
Cox NJ; Division of Genetic Medicine, Department of Medicine, Vanderbilt University, Nashville, TN, United States of America.
Valladares-Salgado A; Unidad de Investigación Médica en Bioquímica, Hospital de Especialidades, Centro Médico Nacional Siglo XXI, IMSS, Mexico City, Mexico.
Below JE; Department of Epidemiology, Human Genetics & Environmental Sciences, University of Texas School of Public Health, Houston, TX, United States of America.
Cruz M; Unidad de Investigación Médica en Bioquímica, Hospital de Especialidades, Centro Médico Nacional Siglo XXI, IMSS, Mexico City, Mexico.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2017 Feb 28; Vol. 12 (2), pp. e0172880. Date of Electronic Publication: 2017 Feb 28 (Print Publication: 2017).
Typ publikacji:: Journal Article
MeSH Terms:: Apolipoprotein A-V/*genetics
Carrier Proteins/*genetics
RNA-Binding Proteins/*genetics
Triglycerides/*blood
Adult ; Alleles ; Female ; Gene Frequency/genetics ; Genetic Predisposition to Disease ; Genome-Wide Association Study ; Haplotypes/genetics ; Humans ; Linkage Disequilibrium/genetics ; Male ; Membrane Transport Proteins ; Mexican Americans ; Middle Aged ; Polymorphism, Single Nucleotide/genetics ; White People

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Skocz do pozycji: 17.

Tytuł:: MARV: a tool for genome-wide multi-phenotype analysis of rare variants.
Autorzy:: Kaakinen M; Department of Genomics of Common Disease, Imperial College London, London, W12 0NN, UK. .
Mägi R; Estonian Genome Center, University of Tartu, Tartu, 51010, Estonia.
Fischer K; Estonian Genome Center, University of Tartu, Tartu, 51010, Estonia.
Heikkinen J; Department of Genomics of Common Disease, Imperial College London, London, W12 0NN, UK.; Neuroepidemiology and Ageing (NEA) Research Unit, Imperial College London, London, W6 8RP, UK.
Järvelin MR; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, W2 1PG, UK.; Center for Life Course Health Research, University of Oulu, 90014, Oulu, Finland.; Unit of Primary Care, Oulu University Hospital, 90220, Oulu, Finland.; Biocenter Oulu, University of Oulu, 90014, Oulu, Finland.
Morris AP; Department of Biostatistics, University of Liverpool, Liverpool, L69 3BX, UK.
Prokopenko I; Department of Genomics of Common Disease, Imperial College London, London, W12 0NN, UK. .; Pokaż więcej
Źródło:: BMC bioinformatics [BMC Bioinformatics] 2017 Feb 16; Vol. 18 (1), pp. 110. Date of Electronic Publication: 2017 Feb 16.
Typ publikacji:: Journal Article
MeSH Terms:: Phenotype*
Software*
Computational Biology/*methods
Genetic Variation/*genetics
Genome-Wide Association Study/*methods
Genotype ; Humans

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Skocz do pozycji: 18.

Tytuł:: SCOPA and META-SCOPA: software for the analysis and aggregation of genome-wide association studies of multiple correlated phenotypes.
Autorzy:: Mägi R; Estonian Genome Center, University of Tartu, Tartu, Estonia.
Suleimanov YV; Computation-based Science and Technology Research Center, Cyprus Institute, Nicosia, Cyprus.; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
Clarke GM; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.
Kaakinen M; Genomics of Common Disease, Imperial College, London, UK.
Fischer K; Estonian Genome Center, University of Tartu, Tartu, Estonia.
Prokopenko I; Genomics of Common Disease, Imperial College, London, UK.
Morris AP; Estonian Genome Center, University of Tartu, Tartu, Estonia. .; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK. .; Department of Biostatistics, University of Liverpool, Liverpool, UK. .; Pokaż więcej
Źródło:: BMC bioinformatics [BMC Bioinformatics] 2017 Jan 11; Vol. 18 (1), pp. 25. Date of Electronic Publication: 2017 Jan 11.
Typ publikacji:: Journal Article
MeSH Terms:: Body Mass Index*
Cholesterol, HDL/*genetics
Cholesterol, LDL/*genetics
Genome-Wide Association Study/*methods
Obesity/*genetics
Triglycerides/*genetics
Cholesterol, HDL/metabolism ; Cholesterol, LDL/metabolism ; Humans ; Models, Theoretical ; Obesity/metabolism ; Phenotype ; Software ; Triglycerides/metabolism

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Tytuł:: SurvivalGWAS_Power: a user friendly tool for power calculations in pharmacogenetic studies with "time to event" outcomes.
Autorzy:: Syed H; Department of Biostatistics, University of Liverpool, Liverpool, UK. .
Jorgensen AL; Department of Biostatistics, University of Liverpool, Liverpool, UK.
Morris AP; Department of Biostatistics, University of Liverpool, Liverpool, UK.; Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, UK.; Pokaż więcej
Źródło:: BMC bioinformatics [BMC Bioinformatics] 2016 Dec 08; Vol. 17 (1), pp. 523. Date of Electronic Publication: 2016 Dec 08.
Typ publikacji:: Journal Article
MeSH Terms:: Pharmacogenetics*
Research Design*
Software*
Computational Biology/*methods
Pharmacogenomic Testing/*methods
Polymorphism, Single Nucleotide/*genetics
Genome-Wide Association Study ; Humans ; Phenotype ; Proportional Hazards Models ; Sample Size ; Survival Rate

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Skocz do pozycji: 20.

Tytuł:: No Association of Coronary Artery Disease with X-Chromosomal Variants in Comprehensive International Meta-Analysis.
Autorzy:: Loley C; Institut für Medizinische Biometrie und Statistik, Universität zu Lübeck, Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Lübeck, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Hamburg-Lübeck-Kiel, Lübeck, Germany.
Alver M; Estonian Genome Center, University of Tartu, Tartu, Estonia.; Institute of Molecular and Cell Biology, Tartu, Estonia.
Assimes TL; Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine Stanford, Standford, California, USA.
Bjonnes A; Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA.
Goel A; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.
Gustafsson S; Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
Hernesniemi J; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Department of Cardiology, Heart Hospital and University of Tampere School of Medicine, Tampere, Finland.
Hopewell JC; CTSU, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Kanoni S; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
Kleber ME; Vth Department of Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Lau KW; CTSU, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Lu Y; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, USA.
Lyytikäinen LP; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Department of Clinical Chemistry, University of Tampere School of Medicine, Tampere, Finland.
Nelson CP; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, Leicester, UK.
Nikpay M; Ruddy Canadian Cardiovascular Genetics Centre University of Ottawa Heart Institute, Ottawa, Canada.
Qu L; Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Salfati E; Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine Stanford, Standford, California, USA.
Scholz M; Institute for Medical Informatics, Statistics and Epidemiology/Medical Faculty/University of Leipzig, Leipzig, Germany.; LIFE Research Center of Civilization Diseases, Leipzig, Germany.
Tukiainen T; Analytic and Translation Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts, USA.; Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, USA.
Willenborg C; DZHK (German Centre for Cardiovascular Research), partner site Hamburg-Lübeck-Kiel, Lübeck, Germany.; Institut für Integrative und Experimentelle Genomik, Universität zu Lübeck, Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Lübeck, Germany and University Heart Center Luebeck, Campus Lübeck, Lübeck, Germany.
Won HH; Samsung Advanced Institute for Health Sciences and Technology (SAIHST), Sungkyunkwan University, Samsung Medical Center, Seoul, Korea.
Zeng L; Deutsches Herzzentrum München, Technische Universität München, Munich, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, München, Germany.
Zhang W; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Department of Cardiology, Ealing Hospital National Health Service (NHS) Trust, Middlesex, UK.
Anand SS; Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada.
Beutner F; LIFE Research Center of Civilization Diseases, Leipzig, Germany.; Heart Center Leipzig, Cardiology, University of Leipzig, Leipzig, Germany.
Bottinger EP; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, USA.
Clarke R; CTSU, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Dedoussis G; Harokopio University Athens, Athens, Greece.
Do R; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, USA.; The Center for Statistical Genetics, Icahn School of Medicine at Mount Sinai, New York, USA.; The Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, USA.; The Zena and Michael A. Weiner Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, USA.
Esko T; Estonian Genome Center, University of Tartu, Tartu, Estonia.; Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA.
Eskola M; Department of Cardiology, Heart Hospital and University of Tampere School of Medicine, Tampere, Finland.
Farrall M; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.
Gauguier D; INSERM, UMRS1138, Centre de Recherche des Cordeliers, Paris, France.
Giedraitis V; Department of Public Health and Caring Sciences, Geriatrics, Uppsala Universit, Uppsala, Sweden.
Granger CB; Duke University School of Medicine, Durham, North Carolina, USA.
Hall AS; Leeds Institute of Genetics, Health and Therapeutics, University of Leeds, UK.
Hamsten A; Cardiovascular Genetics and Genomics Group, Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.
Hazen SL; Cleveland Clinic, Cleveland, Ohio, USA.
Huang J; Boston VA Research Institute, Inc., Boston, Massachusetts, USA.
Kähönen M; Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland.; Department of Clinical Physiology, University of Tampere School of Medicine, Tampere, Finland.
Kyriakou T; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.
Laaksonen R; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Department of Clinical Chemistry, University of Tampere School of Medicine, Tampere, Finland.; Zora Biosciences, Espoo, Finland.
Lind L; Department of Medical Sciences, Cardiovascular Epidemiology, Uppsala University, Uppsala, Sweden.
Lindgren C; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts, USA.
Magnusson PK; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Marouli E; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
Mihailov E; Estonian Genome Center, University of Tartu, Tartu, Estonia.
Morris AP; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Department of Biostatistics, University of Liverpool, Liverpool, UK.
Nikus K; Department of Cardiology, Heart Hospital and University of Tampere School of Medicine, Tampere, Finland.
Pedersen N; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Rallidis L; Second Department of Cardiology, University General Hospital Attikon, Athens, Greece.
Salomaa V; Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland.
Shah SH; Duke University School of Medicine, Durham, North Carolina, USA.
Stewart AF; Ruddy Canadian Cardiovascular Genetics Centre University of Ottawa Heart Institute, Ottawa, Canada.
Thompson JR; Department of Health Sciences, University of Leicester, Leicester, UK.
Zalloua PA; Lebanese American University, School of Medicine, Beirut, Lebanon.; Harvard School of Public Health, Boston, Massachusetts, USA.
Chambers JC; Department of Cardiology, Ealing Hospital National Health Service (NHS) Trust, Middlesex, UK.; Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada.; Imperial College Healthcare NHS Trust, London, UK.
Collins R; CTSU, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Ingelsson E; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
Iribarren C; Kaiser Permanente, Division of Research, Oakland, California, USA.
Karhunen PJ; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Department of Forensic Medicine, University of Tampere School of Medicine, Tampere, Finland.
Kooner JS; Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada.; Imperial College Healthcare NHS Trust, London, UK.; Cardiovascular Science, National Heart and Lung Institute, Imperial College London, London, UK.
Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Department of Clinical Chemistry, University of Tampere School of Medicine, Tampere, Finland.
Loos RJ; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, USA.; The Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, USA.
März W; Vth Department of Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.; Synlab Academy, Synlab Services GmbH, Mannheim, Germany.; Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria.
McPherson R; Ruddy Canadian Cardiovascular Genetics Centre University of Ottawa Heart Institute, Ottawa, Canada.
Metspalu A; Estonian Genome Center, University of Tartu, Tartu, Estonia.; Institute of Molecular and Cell Biology, Tartu, Estonia.
Reilly MP; Cardiovascular Institute, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Ripatti S; Kaiser Permanente, Division of Research, Oakland, California, USA.; Hjelt Institute, University of Helsinki, Helsinki, Finland.; Institute for Molecular Medicine Finland FIMM, University of Helsinki, Helsinki, Finland.
Sanghera DK; Department of Pediatrics, College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA.; Department of Pharmaceutical Sciences, College of Pharmacy, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA.; Oklahoma Center for Neuroscience, Oklahoma City, Oklahoma, USA.
Thiery J; LIFE Research Center of Civilization Diseases, Leipzig, Germany.; Institute for Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Hospital Leipzig, Medical Faculty, Leipzig, Germany.
Watkins H; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.
Deloukas P; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK.; Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders (PACER-HD), King Abdulaziz University, Jeddah, Saudi Arabia.
Kathiresan S; Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA.; Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, USA.; Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA.; Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA.
Samani NJ; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, Leicester, UK.
Schunkert H; DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, München, Germany.; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.
Erdmann J; DZHK (German Centre for Cardiovascular Research), partner site Hamburg-Lübeck-Kiel, Lübeck, Germany.; Institut für Integrative und Experimentelle Genomik, Universität zu Lübeck, Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Lübeck, Germany and University Heart Center Luebeck, Campus Lübeck, Lübeck, Germany.
König IR; Institut für Medizinische Biometrie und Statistik, Universität zu Lübeck, Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Lübeck, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Hamburg-Lübeck-Kiel, Lübeck, Germany.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2016 Oct 12; Vol. 6, pp. 35278. Date of Electronic Publication: 2016 Oct 12.
Typ publikacji:: Journal Article; Meta-Analysis; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Chromosomes, Human, X*
Coronary Artery Disease/*genetics
Cohort Studies ; Female ; Humans ; Internationality ; Male

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