Autor: "Mu, Junhao" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: The new 6q27 tumor suppressor DACT2, frequently silenced by CpG methylation, sensitizes nasopharyngeal cancer cells to paclitaxel and 5-FU toxicity via β-catenin/Cdc25c signaling and G2/M arrest.
Autorzy:: Zhang Y; Chongqing Key Laboratory of Molecular Oncology and Epigenetics, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Fan J; Chongqing Key Laboratory of Molecular Oncology and Epigenetics, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Fan Y; Cancer Epigenetics Laboratory, Department of Clinical Oncology, Sir YK Pao Center for Cancer and Li Ka Shing Institute of Health Sciences, CUHK-Shenzhen Research Institute, The Chinese University of Hong Kong, Hong Kong, China.
Li L; Cancer Epigenetics Laboratory, Department of Clinical Oncology, Sir YK Pao Center for Cancer and Li Ka Shing Institute of Health Sciences, CUHK-Shenzhen Research Institute, The Chinese University of Hong Kong, Hong Kong, China.
He X; Chongqing Key Laboratory of Molecular Oncology and Epigenetics, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Xiang Q; Chongqing Key Laboratory of Molecular Oncology and Epigenetics, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Mu J; Chongqing Key Laboratory of Molecular Oncology and Epigenetics, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Zhou D; Chongqing Key Laboratory of Molecular Oncology and Epigenetics, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Sun X; Chongqing Key Laboratory of Molecular Oncology and Epigenetics, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Yang Y; Department of Otolaryngology, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Ren G; Chongqing Key Laboratory of Molecular Oncology and Epigenetics, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Tao Q; Chongqing Key Laboratory of Molecular Oncology and Epigenetics, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China. .; Cancer Epigenetics Laboratory, Department of Clinical Oncology, Sir YK Pao Center for Cancer and Li Ka Shing Institute of Health Sciences, CUHK-Shenzhen Research Institute, The Chinese University of Hong Kong, Hong Kong, China. .
Xiang T; Chongqing Key Laboratory of Molecular Oncology and Epigenetics, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China. .; Pokaż więcej
Źródło:: Clinical epigenetics [Clin Epigenetics] 2018 Feb 27; Vol. 10 (1), pp. 26. Date of Electronic Publication: 2018 Feb 27.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: DNA Methylation*
Carcinoma/*genetics
Carrier Proteins/*genetics
Fluorouracil/*pharmacology
Nasopharyngeal Neoplasms/*genetics
Neoplasm Proteins/*genetics
Paclitaxel/*pharmacology
Signal Transduction/*drug effects
Adaptor Proteins, Signal Transducing ; Carcinoma/drug therapy ; Cell Line, Tumor ; Cell Movement/drug effects ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; CpG Islands ; Down-Regulation/drug effects ; G2 Phase Cell Cycle Checkpoints/drug effects ; Gene Expression Regulation, Neoplastic/drug effects ; Humans ; Nasopharyngeal Neoplasms/drug therapy ; Promoter Regions, Genetic ; beta Catenin/genetics ; beta Catenin/metabolism ; cdc25 Phosphatases/genetics ; cdc25 Phosphatases/metabolism

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Skocz do pozycji: 2.

Tytuł:: TET1 exerts its anti-tumor functions via demethylating DACT2 and SFRP2 to antagonize Wnt/β-catenin signaling pathway in nasopharyngeal carcinoma cells.
Autorzy:: Fan J; Chongqing Key Laboratory of Molecular Oncology and Epigenetics, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Zhang Y; Chongqing Key Laboratory of Molecular Oncology and Epigenetics, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Mu J; Chongqing Key Laboratory of Molecular Oncology and Epigenetics, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
He X; Chongqing Key Laboratory of Molecular Oncology and Epigenetics, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Shao B; Chongqing Key Laboratory of Molecular Oncology and Epigenetics, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Zhou D; Chongqing Key Laboratory of Molecular Oncology and Epigenetics, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Peng W; Chongqing Key Laboratory of Molecular Oncology and Epigenetics, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Tang J; Chongqing Key Laboratory of Molecular Oncology and Epigenetics, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Jiang Y; Chongqing Key Laboratory of Molecular Oncology and Epigenetics, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Ren G; Chongqing Key Laboratory of Molecular Oncology and Epigenetics, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Xiang T; Chongqing Key Laboratory of Molecular Oncology and Epigenetics, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China. .; Pokaż więcej
Źródło:: Clinical epigenetics [Clin Epigenetics] 2018 Aug 03; Vol. 10 (1), pp. 103. Date of Electronic Publication: 2018 Aug 03.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Wnt Signaling Pathway*
Carrier Proteins/*genetics
Membrane Proteins/*genetics
Mixed Function Oxygenases/*genetics
Nasopharyngeal Carcinoma/*genetics
Nasopharyngeal Neoplasms/*genetics
Neoplasm Proteins/*genetics
Proto-Oncogene Proteins/*genetics
Adaptor Proteins, Signal Transducing ; Aged ; Apoptosis ; Cell Cycle ; Cell Line, Tumor ; Cell Movement ; DNA Methylation ; Down-Regulation ; Epigenesis, Genetic ; Epithelial-Mesenchymal Transition ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; Male ; Middle Aged ; Promoter Regions, Genetic ; Sequence Analysis, DNA

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