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Tytuł:
Novel KMT2B gene mutation in MUC4 positive low-grade fibromyxoid sarcoma.
Autorzy:
Zhang L; Department of Pathology, Cancer Hospital of Shantou University Medical College, Shantou, China.; Department of Pathology, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
Luo L; Department of Pathology, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
Liu C; Department of Pathology, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
Li Z; Department of Pathology, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China. .
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Źródło:
Diagnostic pathology [Diagn Pathol] 2024 Feb 12; Vol. 19 (1), pp. 30. Date of Electronic Publication: 2024 Feb 12.
Typ publikacji:
Case Reports; Journal Article
MeSH Terms:
Fibrosarcoma*/pathology
Soft Tissue Neoplasms*/pathology
Female ; Humans ; Middle Aged ; Biomarkers, Tumor/genetics ; Collagen/genetics ; Histone-Lysine N-Methyltransferase/genetics ; Mucin-4/genetics ; Translocation, Genetic
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Characterization of recombinant β subunit of human MUC4 mucin (rMUC4β).
Autorzy:
Kshirsagar PG; Department of Biochemistry and Molecular Biology, College of Medicine, University of Nebraska Medical Center, 985870 Nebraska Medical Center, Omaha, NE, 68198-5870, USA.
Gulati M; Department of Biochemistry and Molecular Biology, College of Medicine, University of Nebraska Medical Center, 985870 Nebraska Medical Center, Omaha, NE, 68198-5870, USA.
Junker WM; Department of Biochemistry and Molecular Biology, College of Medicine, University of Nebraska Medical Center, 985870 Nebraska Medical Center, Omaha, NE, 68198-5870, USA.; Sanguine Diagnostics and Therapeutics, Omaha, NE, USA.
Aithal A; Department of Biochemistry and Molecular Biology, College of Medicine, University of Nebraska Medical Center, 985870 Nebraska Medical Center, Omaha, NE, 68198-5870, USA.
Spagnol G; Department of Biochemistry and Molecular Biology, College of Medicine, University of Nebraska Medical Center, 985870 Nebraska Medical Center, Omaha, NE, 68198-5870, USA.
Das S; Department of Biochemistry and Molecular Biology, College of Medicine, University of Nebraska Medical Center, 985870 Nebraska Medical Center, Omaha, NE, 68198-5870, USA.
Mallya K; Department of Biochemistry and Molecular Biology, College of Medicine, University of Nebraska Medical Center, 985870 Nebraska Medical Center, Omaha, NE, 68198-5870, USA.
Gautam SK; Department of Biochemistry and Molecular Biology, College of Medicine, University of Nebraska Medical Center, 985870 Nebraska Medical Center, Omaha, NE, 68198-5870, USA.
Kumar S; Department of Biochemistry and Molecular Biology, College of Medicine, University of Nebraska Medical Center, 985870 Nebraska Medical Center, Omaha, NE, 68198-5870, USA.
Sorgen P; Department of Biochemistry and Molecular Biology, College of Medicine, University of Nebraska Medical Center, 985870 Nebraska Medical Center, Omaha, NE, 68198-5870, USA.
Pandey KK; Department of Molecular Microbiology and Immunology, Saint Louis University Health Sciences Center, St. Louis, MO, USA.
Batra SK; Department of Biochemistry and Molecular Biology, College of Medicine, University of Nebraska Medical Center, 985870 Nebraska Medical Center, Omaha, NE, 68198-5870, USA. .; Sanguine Diagnostics and Therapeutics, Omaha, NE, USA. .; Fred and Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, NE, USA. .; Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, NE, USA. .
Jain M; Department of Biochemistry and Molecular Biology, College of Medicine, University of Nebraska Medical Center, 985870 Nebraska Medical Center, Omaha, NE, 68198-5870, USA. .; Fred and Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, NE, USA. .
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Źródło:
Scientific reports [Sci Rep] 2021 Dec 09; Vol. 11 (1), pp. 23730. Date of Electronic Publication: 2021 Dec 09.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Protein Subunits*
Recombinant Proteins*
Mucin-4/*genetics
Mucin-4/*metabolism
Cloning, Molecular ; Gene Expression ; Gene Order ; Humans ; Mass Spectrometry ; Models, Molecular ; Mucin-4/chemistry ; Mucin-4/isolation & purification ; Plasmids/genetics ; Protein Binding ; Structure-Activity Relationship
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Genetic variants of MUC4 are associated with susceptibility to and mortality of colorectal cancer and exhibit synergistic effects with LDL-C levels.
Autorzy:
Kwon MJ; Department of Biomedical Science, College of Life Science, CHA University, Seongnam, South Korea.
Lee JY; Department of Biomedical Science, College of Life Science, CHA University, Seongnam, South Korea.
Kim EJ; Division of Hematology/Oncology, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, South Korea.
Ko EJ; Department of Biomedical Science, College of Life Science, CHA University, Seongnam, South Korea.
Ryu CS; Department of Biomedical Science, College of Life Science, CHA University, Seongnam, South Korea.
Cho HJ; Department of Surgery, CHA Bundang Medical Center, CHA University, Seongnam, South Korea.
Jun HH; Department of Surgery, CHA Bundang Medical Center, CHA University, Seongnam, South Korea.
Kim JW; Department of Surgery, CHA Bundang Medical Center, CHA University, Seongnam, South Korea.
Kim NK; Department of Biomedical Science, College of Life Science, CHA University, Seongnam, South Korea.
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Źródło:
PloS one [PLoS One] 2023 Jun 29; Vol. 18 (6), pp. e0287768. Date of Electronic Publication: 2023 Jun 29 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Mucins*/genetics
Colorectal Neoplasms*/genetics
Humans ; Case-Control Studies ; Cholesterol, LDL ; Homeostasis ; Mucin-4/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Family-based exome sequencing combined with linkage analyses identifies rare susceptibility variants of MUC4 for gastric cancer.
Autorzy:
Choi YJ; Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea.
Ohn JH; Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea.
Kim N; Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea.; Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, South Korea.; Tumor Microenvironment Global Core Research Center, College of Pharmacy, Seoul National University, Seoul, South Korea.
Kim W; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States of America.
Park K; Interdisciplinary Program of Bioinformatics, Seoul National University, Seoul, South Korea.
Won S; Interdisciplinary Program of Bioinformatics, Seoul National University, Seoul, South Korea.; Department of Public Health Sciences, Seoul National University, Seoul, South Korea.; Institute of Health and Environment, Seoul National University, Seoul, South Korea.
Sael L; Department of Artificial Intelligence and Data Science, Ajou University, Seoul, South Korea.
Shin CM; Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea.
Lee SM; Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea.
Lee S; Department of Pathology, Seoul National University Bundang Hospital, Seongnam, South Korea.
An HJ; Graduate School of Analytical Science and Technology, Chungnam National University, Daejeon, South Korea.
Jang DM; Tumor Microenvironment Global Core Research Center, College of Pharmacy, Seoul National University, Seoul, South Korea.
Han BW; Tumor Microenvironment Global Core Research Center, College of Pharmacy, Seoul National University, Seoul, South Korea.
Lee HS; Department of Pathology, Seoul National University Bundang Hospital, Seongnam, South Korea.
Kang SJ; Department of Internal Medicine and Healthcare Research Institute, Healthcare System Gangnam Center, Seoul National University Hospital, Seoul, South Korea.
Kim JS; Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, South Korea.; Department of Internal Medicine and Healthcare Research Institute, Healthcare System Gangnam Center, Seoul National University Hospital, Seoul, South Korea.
Lee DH; Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea.; Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, South Korea.; Tumor Microenvironment Global Core Research Center, College of Pharmacy, Seoul National University, Seoul, South Korea.
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Źródło:
PloS one [PLoS One] 2020 Jul 23; Vol. 15 (7), pp. e0236197. Date of Electronic Publication: 2020 Jul 23 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Genetic Linkage*
Genetic Predisposition to Disease*
Genetic Variation*
Exome Sequencing*
Mucin-4/*genetics
Cohort Studies ; Family ; Female ; Germ Cells/metabolism ; Humans ; Male ; Middle Aged ; Mucin-4/chemistry ; Pedigree ; Reproducibility of Results ; Stomach/pathology ; Stomach Neoplasms/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The diagnostic and prognostic potential of the EGFR/MUC4/MMP9 axis in glioma patients.
Autorzy:
Quesnel A; School of Health & Life Sciences, Teesside University, Middlesbrough, TS1 3BX, UK.; National Horizons Centre, Teesside University, 38 John Dixon Ln, Darlington, DL1 1HG, UK.
Coles N; School of Health & Life Sciences, Teesside University, Middlesbrough, TS1 3BX, UK.; National Horizons Centre, Teesside University, 38 John Dixon Ln, Darlington, DL1 1HG, UK.
Polvikoski TM; Translational and Clinical Research Institute, Newcastle University, Newcastle Upon Tyne, UK.
Karagiannis GS; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY, USA.; Integrated Imaging Program, Albert Einstein College of Medicine, Bronx, NY, USA.; Gruss-Lipper Biophotonics Center, Albert Einstein College of Medicine, Bronx, NY, USA.; Tumor Microenvironment and Metastasis Program, Albert Einstein Cancer Center, Bronx, NY, USA.
Angione C; National Horizons Centre, Teesside University, 38 John Dixon Ln, Darlington, DL1 1HG, UK.; School of Computing, Engineering & Digital Technologies, Teesside University, Middlesbrough, UK.; Centre for Digital Innovation, Teesside University, Middlesbrough, UK.
Islam M; School of Health & Life Sciences, Teesside University, Middlesbrough, TS1 3BX, UK.; National Horizons Centre, Teesside University, 38 John Dixon Ln, Darlington, DL1 1HG, UK.
Khundakar AA; School of Health & Life Sciences, Teesside University, Middlesbrough, TS1 3BX, UK.; National Horizons Centre, Teesside University, 38 John Dixon Ln, Darlington, DL1 1HG, UK.; Translational and Clinical Research Institute, Newcastle University, Newcastle Upon Tyne, UK.
Filippou PS; School of Health & Life Sciences, Teesside University, Middlesbrough, TS1 3BX, UK. .; National Horizons Centre, Teesside University, 38 John Dixon Ln, Darlington, DL1 1HG, UK. .
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Źródło:
Scientific reports [Sci Rep] 2022 Nov 18; Vol. 12 (1), pp. 19868. Date of Electronic Publication: 2022 Nov 18.
Typ publikacji:
Journal Article
MeSH Terms:
Glioblastoma*/diagnosis
Glioblastoma*/metabolism
Glioma*/diagnosis
Humans ; Mucin-4/metabolism ; Matrix Metalloproteinase 9/metabolism ; Prognosis ; ErbB Receptors/metabolism ; Biomarkers
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Thymoquinone-Induced Tristetraprolin Inhibits Tumor Growth and Metastasis through Destabilization of MUC4 mRNA.
Autorzy:
Lee SR; Department of Biological Science, Dong-A University, Busan 49315, Korea. .; Division of Drug Development & Optimization, Osong Medical Innovation Foundation (KBio), Chungbuk 28160, Korea. .
Mun JY; Department of Biological Science, Dong-A University, Busan 49315, Korea. .
Jeong MS; Department of Biological Science, Dong-A University, Busan 49315, Korea. .
Lee HH; Department of Biological Science, Dong-A University, Busan 49315, Korea. .
Roh YG; Department of Biological Science, Dong-A University, Busan 49315, Korea. .
Kim WT; Department of Biological Science, Dong-A University, Busan 49315, Korea. .
Kim MH; Department of Biological Science, Dong-A University, Busan 49315, Korea. .
Heo J; Departments of Molecular Biology and Immunology, College of Medicine, Kosin University, Busan 49267, Korea. .
Choi YH; Department of Biochemistry, College of Oriental Medicine, Anti-Aging Research Center, Dongeui University, Busan 47227, Korea. .
Kim SJ; Department of Pathology, College of Medicine, Dong-A University, Busan 49315, Korea. tina_.
Cha HJ; Department of Parasitology and Genetics, Kosin University College of Medicine, Busan 602-702, Korea. .
Jun M; Department of Food Science and Nutrition, Dong-A University, Busan 49315, Korea. .
Leem SH; Department of Biological Science, Dong-A University, Busan 49315, Korea. .
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2019 May 28; Vol. 20 (11). Date of Electronic Publication: 2019 May 28.
Typ publikacji:
Journal Article
MeSH Terms:
Antineoplastic Agents/*pharmacology
Benzoquinones/*pharmacology
Mucin-4/*genetics
Neoplasms, Experimental/*drug therapy
Tristetraprolin/*metabolism
Animals ; Antineoplastic Agents/therapeutic use ; Benzoquinones/therapeutic use ; Cell Line ; Cell Movement/drug effects ; Cell Proliferation/drug effects ; Female ; Humans ; MCF-7 Cells ; Mice ; Mice, Inbred C57BL ; Mucin-4/metabolism ; RNA Stability ; RNA, Messenger/genetics ; RNA, Messenger/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Single nucleotide polymorphisms within MUC4 are associated with colorectal cancer survival.
Autorzy:
Lu S; Division of Molecular Genetic Epidemiology, German Cancer Research Center, Heidelberg, Germany.; Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China.
Catalano C; Division of Molecular Genetic Epidemiology, German Cancer Research Center, Heidelberg, Germany.
Huhn S; Division of Molecular Genetic Epidemiology, German Cancer Research Center, Heidelberg, Germany.; Department of Multiple Myeloma, Internal Medicine V: Hematology, Oncology and Rheumatology, Heidelberg University Hospital, Heidelberg, Germany.
Pardini B; Italian Institute for Genomic Medicine (IIGM), Turin, Italy.
Partu L; Department of Molecular Biology of Cancer, Institute of Experimental Medicine, Academy of Sciences of the Czech Republic, Prague, Czech Republic.; Department of Medical Genetics, Third Faculty of Medicine, Charles University, Prague, Czech Republic.
Vymetalkova V; Department of Molecular Biology of Cancer, Institute of Experimental Medicine, Academy of Sciences of the Czech Republic, Prague, Czech Republic.; Institute of Biology and Medical Genetics, 1stMedical Faculty, Charles University, Prague, Czech Republic.
Vodickova L; Department of Molecular Biology of Cancer, Institute of Experimental Medicine, Academy of Sciences of the Czech Republic, Prague, Czech Republic.; Institute of Biology and Medical Genetics, 1stMedical Faculty, Charles University, Prague, Czech Republic.; Biomedical Centre, Faculty of Medicine in Pilsen, Charles University in Prague, Pilsen, Czech Republic.
Levy M; Department of Oncology, Thomayer Hospital, Prague, Czech Republic.
Buchler T; Department of Oncology, Thomayer Hospital, Prague, Czech Republic.
Hemminki K; Division of Molecular Genetic Epidemiology, German Cancer Research Center, Heidelberg, Germany.; Center of Primary Health Care Research, Clinical Research Center, Lund University, Malmö, Sweden.
Vodicka P; Department of Molecular Biology of Cancer, Institute of Experimental Medicine, Academy of Sciences of the Czech Republic, Prague, Czech Republic.; Institute of Biology and Medical Genetics, 1stMedical Faculty, Charles University, Prague, Czech Republic.; Biomedical Centre, Faculty of Medicine in Pilsen, Charles University in Prague, Pilsen, Czech Republic.
Försti A; Division of Molecular Genetic Epidemiology, German Cancer Research Center, Heidelberg, Germany.; Center of Primary Health Care Research, Clinical Research Center, Lund University, Malmö, Sweden.
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Źródło:
PloS one [PLoS One] 2019 May 15; Vol. 14 (5), pp. e0216666. Date of Electronic Publication: 2019 May 15 (Print Publication: 2019).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Colorectal Neoplasms/*genetics
Mucin-4/*genetics
Adult ; Aged ; Aged, 80 and over ; Biomarkers, Tumor/genetics ; Case-Control Studies ; Colonic Neoplasms/genetics ; Colonic Neoplasms/mortality ; Colonic Neoplasms/pathology ; Colorectal Neoplasms/mortality ; Colorectal Neoplasms/pathology ; Czech Republic ; Disease-Free Survival ; Female ; Genotype ; Glycosylation ; Humans ; Kaplan-Meier Estimate ; Linkage Disequilibrium ; Male ; Middle Aged ; Mucin-4/metabolism ; Mucins/genetics ; Mucins/metabolism ; Polymorphism, Single Nucleotide/genetics ; Progression-Free Survival ; Risk Factors
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
MUC4 expression by immunohistochemistry is a specific marker for BCR-ABL1+ and BCR-ABL1 -like B-lymphoblastic leukemia.
Autorzy:
Kaumeyer B; Department of Pathology, University of Chicago, Chicago, IL, USA.
Fidai S; Department of Pathology, University of Chicago, Chicago, IL, USA.; Department of Pathology and Laboratory Medicine, John H. Stroger Hospital of Cook County, Chicago, IL, USA.
Sukhanova M; Department of Medicine. University of Chicago, Chicago, IL, USA.; Department of Pathology & Laboratory Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Yap KL; Department of Medicine. University of Chicago, Chicago, IL, USA.; Department of Pathology & Laboratory Medicine, Ann & Robert H. Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Segal J; Department of Pathology, University of Chicago, Chicago, IL, USA.
Raca G; Department of Medicine. University of Chicago, Chicago, IL, USA.; Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Keck School of Medicine, University of Southern California, California, LA, USA.
Stock W; Department of Medicine. University of Chicago, Chicago, IL, USA.
McNeer J; Department of Pediatrics, University of Chicago, Chicago, IL, USA.
Lager AM; Department of Medicine. University of Chicago, Chicago, IL, USA.
Gurbuxani S; Department of Pathology, University of Chicago, Chicago, IL, USA.
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Źródło:
Leukemia & lymphoma [Leuk Lymphoma] 2022 Jun; Vol. 63 (6), pp. 1436-1444. Date of Electronic Publication: 2022 Feb 16.
Typ publikacji:
Journal Article
MeSH Terms:
Leukemia, B-Cell*
Precursor Cell Lymphoblastic Leukemia-Lymphoma*/diagnosis
Biomarkers ; Fusion Proteins, bcr-abl/genetics ; Humans ; Immunohistochemistry ; Mucin-4/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Integrative analysis of the cancer genome atlas and cancer cell lines encyclopedia large-scale genomic databases: MUC4/MUC16/MUC20 signature is associated with poor survival in human carcinomas.
Autorzy:
Jonckheere N; Inserm, CHU Lille, UMR-S 1172-JPARC-Jean-Pierre Aubert Research Center, Team 'Mucins, epithelial differentiation and carcinogenesis', Univ. Lille, 59000, Lille, France. .
Van Seuningen I; Inserm, CHU Lille, UMR-S 1172-JPARC-Jean-Pierre Aubert Research Center, Team 'Mucins, epithelial differentiation and carcinogenesis', Univ. Lille, 59000, Lille, France. .
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Źródło:
Journal of translational medicine [J Transl Med] 2018 Sep 20; Vol. 16 (1), pp. 259. Date of Electronic Publication: 2018 Sep 20.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Databases, Genetic*
Genome, Human*
Genomics*
CA-125 Antigen/*genetics
Membrane Proteins/*genetics
Mucin-4/*genetics
Mucins/*genetics
CA-125 Antigen/metabolism ; Cell Line, Tumor ; Cluster Analysis ; Gene Expression Regulation, Neoplastic ; Gene Ontology ; Humans ; Membrane Proteins/metabolism ; Mucin-4/metabolism ; Mucins/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; ROC Curve ; Survival Analysis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Recurring exposure to low humidity induces transcriptional and protein level changes in the vocal folds of rabbits.
Autorzy:
Bailey TW; Department of Comparative Pathobiology, Purdue University, West Lafayette, IN, 47907, USA.; Department of Public Health, Purdue University, West Lafayette, IN, 47907, USA.; Department of Statistics, Purdue University, West Lafayette, IN, 47909, USA.
Dos Santos AP; Department of Comparative Pathobiology, Purdue University, West Lafayette, IN, 47907, USA.
do Nascimento NC; Department of Speech, Language, and Hearing Sciences, Purdue University, West Lafayette, IN, 47907, USA.
Xie J; Department of Statistics, Purdue University, West Lafayette, IN, 47909, USA.
Sivasankar MP; Department of Speech, Language, and Hearing Sciences, Purdue University, West Lafayette, IN, 47907, USA.
Cox A; Department of Comparative Pathobiology, Purdue University, West Lafayette, IN, 47907, USA. .
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Źródło:
Scientific reports [Sci Rep] 2021 Dec 17; Vol. 11 (1), pp. 24180. Date of Electronic Publication: 2021 Dec 17.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Humidity/*adverse effects
Proteomics/*methods
Vocal Cords/*metabolism
Voice Disorders/*etiology
Animals ; Chloride Channels/metabolism ; Cohort Studies ; Computational Biology ; Dehydration/metabolism ; Environmental Exposure ; Epithelial Sodium Channels/metabolism ; Larynx ; Matrix Metalloproteinase 1/genetics ; Matrix Metalloproteinase 12/genetics ; Mucin-4/metabolism ; Prospective Studies ; Rabbits ; Signal Transduction
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
MUC4 is a valuable marker for distinguishing secretory carcinoma of the salivary glands from its mimics.
Autorzy:
Taverna C; Institute of Pathology, Friedrich-Alexander-University Erlangen-Nürnberg, University Hospital, Erlangen, Germany.; Department of Laboratory Medicine, Unit of Anatomical Pathology, Pisa University Hospital, Pisa, Italy.
Baněčková M; Department of Pathology, Faculty of Medicine in Plzen, Charles University, Plzen, Czech Republic.
Lorenzon M; The Molecular Foundry, Lawrence Berkeley National Laboratory, Berkeley, CA, USA.
Palomba A; Unit of Histopathology and Molecular Diagnostics, Careggi University Hospital, Florence, Italy.
Franchi A; Department of Translational Research, School of Medicine, University of Pisa, Pisa, Italy.
Skalova A; Department of Pathology, Faculty of Medicine in Plzen, Charles University, Plzen, Czech Republic.
Agaimy A; Institute of Pathology, Friedrich-Alexander-University Erlangen-Nürnberg, University Hospital, Erlangen, Germany.
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Źródło:
Histopathology [Histopathology] 2021 Sep; Vol. 79 (3), pp. 315-324. Date of Electronic Publication: 2020 Nov 09.
Typ publikacji:
Journal Article
MeSH Terms:
Diagnosis, Differential*
Salivary Gland Neoplasms*/diagnosis
Salivary Gland Neoplasms*/metabolism
Salivary Gland Neoplasms*/pathology
Mammary Analogue Secretory Carcinoma/*diagnosis
Mucin-4/*analysis
Biomarkers, Tumor/analysis ; Carcinoma/diagnosis ; Carcinoma/pathology ; Carcinoma, Acinar Cell/diagnosis ; Carcinoma, Acinar Cell/pathology ; Humans ; Mammaglobin A/metabolism ; Mammary Analogue Secretory Carcinoma/metabolism ; Mammary Analogue Secretory Carcinoma/pathology ; Salivary Glands/pathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Sclerosing epithelioid fibrosarcoma: in-depth review of a genetically heterogeneous tumor.
Autorzy:
Murshed KA; Department of Laboratory Medicine & Pathology, Hamad Medical Corporation, Doha, Qatar.
Al-Bozom I; Department of Laboratory Medicine & Pathology, Hamad Medical Corporation, Doha, Qatar.
Ammar A; Department of Laboratory Medicine & Pathology, Hamad Medical Corporation, Doha, Qatar.
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Źródło:
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica [APMIS] 2021 Aug; Vol. 129 (8), pp. 455-460. Date of Electronic Publication: 2021 Jun 25.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Fibrosarcoma/*genetics
Soft Tissue Neoplasms/*genetics
Animals ; Fibrosarcoma/pathology ; Gene Rearrangement ; Humans ; Mucin-4/genetics ; Soft Tissue Neoplasms/pathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The role of the AMOP domain in MUC4/Y-promoted tumour angiogenesis and metastasis in pancreatic cancer.
Autorzy:
Tang J; Department of General Surgery, the First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.; Department of Pediatric Surgery, Nanjing Children's Hospital Affiliated to Nanjing Medical University, Nanjing, Jiangsu, China.
Zhu Y; Department of General Surgery, the First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.
Xie K; Department of General Surgery, the First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.; Department of General Surgery, the People's Hospital of Bozhou, Bozhou, Anhui, China.
Zhang X; Department of General Surgery, the First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.; Department of General Surgery, Huai'an People's Hospital, Xuzhou Medical College, Huai'an, Jiangsu, China.
Zhi X; Department of General Surgery, the First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.; Department of General Surgery, Affiliated Hospital of Nantong University, Nantong, Jiangsu, China.
Wang W; Department of General Surgery, the First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.
Li Z; Department of General Surgery, the First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.
Zhang Q; Department of General Surgery, the First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.
Wang L; Department of General Surgery, the First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.
Wang J; Department of General Surgery, the First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.
Xu Z; Department of General Surgery, the First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China. .
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Źródło:
Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2016 Jun 10; Vol. 35 (1), pp. 91. Date of Electronic Publication: 2016 Jun 10.
Typ publikacji:
Journal Article
MeSH Terms:
Mucin-4/*chemistry
Mucin-4/*metabolism
Pancreatic Neoplasms/*blood supply
Pancreatic Neoplasms/*pathology
Animals ; Cell Line, Tumor ; Cell Movement ; Cell Proliferation ; Humans ; Matrix Metalloproteinase 2/metabolism ; Mice ; Mucin-4/genetics ; Neoplasm Metastasis ; Neoplasm Transplantation ; Pancreatic Neoplasms/genetics ; Pancreatic Neoplasms/metabolism ; Protein Domains ; Receptor, Notch3/metabolism ; Signal Transduction ; Survival Analysis ; Vascular Endothelial Growth Factor A/metabolism ; Vesicular Transport Proteins/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Primary sclerosing epithelioid fibrosarcoma of the spine: a single-institution experience.
Autorzy:
Righi A; Department of Pathology, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
Pacheco M; Department of Pathology, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.; Department of Pathology, Complejo Hospitalario Metropolitano CSS, Panama, Panama.
Pipola V; Department of Oncological and Degenerative Spine Surgery, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
Gambarotti M; Department of Pathology, Complejo Hospitalario Metropolitano CSS, Panama, Panama.
Benini S; Department of Pathology, Complejo Hospitalario Metropolitano CSS, Panama, Panama.
Sbaraglia M; Department of Pathology, Azienda Ospedale-Università Padova, Padua, Italy.
Frisoni T; Department of Orthopaedic Oncology, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
Boriani S; IRCCS Istituto Ortopedico Galeazzi, Milano, Italy.
Dei Tos AP; Department of Pathology, Azienda Ospedale-Università Padova, Padua, Italy.; Department of Medicine, University of Padua School of Medicine, Padua, Italy.
Gasbarrini A; Department of Oncological and Degenerative Spine Surgery, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
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Źródło:
Histopathology [Histopathology] 2021 Jun; Vol. 78 (7), pp. 976-986. Date of Electronic Publication: 2021 Apr 14.
Typ publikacji:
Case Reports; Journal Article; Review
MeSH Terms:
Fibrosarcoma*/diagnosis
Fibrosarcoma*/genetics
Fibrosarcoma*/pathology
Epithelioid Cells/*pathology
Adult ; Diagnosis, Differential ; Female ; Gene Rearrangement ; Humans ; In Situ Hybridization, Fluorescence ; Male ; Middle Aged ; Mucin-4/genetics ; RNA-Binding Protein EWS/genetics ; RNA-Binding Protein FUS/genetics ; Soft Tissue Neoplasms/diagnosis ; Soft Tissue Neoplasms/genetics ; Soft Tissue Neoplasms/pathology ; Spine/pathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
MUC4 is expressed in alveolar rhabdomyosarcoma.
Autorzy:
Forgó E; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.
Hornick JL; Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
Charville GW; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.
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Źródło:
Histopathology [Histopathology] 2021 May; Vol. 78 (6), pp. 905-908. Date of Electronic Publication: 2021 Mar 16.
Typ publikacji:
Journal Article
MeSH Terms:
Head and Neck Neoplasms/*metabolism
Mucin-4/*metabolism
Rhabdomyosarcoma, Alveolar/*metabolism
Soft Tissue Neoplasms/*metabolism
Adult ; Female ; Head and Neck Neoplasms/pathology ; Humans ; Rhabdomyosarcoma, Alveolar/pathology ; Soft Tissue Neoplasms/pathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Utility of Immunohistochemistry for MUC4 and GATA3 to Aid in the Distinction of Pleural Sarcomatoid Mesothelioma From Pulmonary Sarcomatoid Carcinoma.
Autorzy:
Terra SBSP; From the Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota.
Roden AC; From the Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota.
Aubry MC; From the Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota.
Yi ESJ; From the Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota.
Boland JM; From the Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota.
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Źródło:
Archives of pathology & laboratory medicine [Arch Pathol Lab Med] 2021 Feb 01; Vol. 145 (2), pp. 208-213.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma/*diagnosis
GATA3 Transcription Factor/*metabolism
Mesothelioma, Malignant/*diagnosis
Mucin-4/*metabolism
Pleural Neoplasms/*diagnosis
Aged ; Aged, 80 and over ; Carcinoma/metabolism ; Carcinoma/pathology ; Cohort Studies ; Diagnosis, Differential ; Female ; Humans ; Immunohistochemistry ; Male ; Mesothelioma, Malignant/metabolism ; Mesothelioma, Malignant/pathology ; Middle Aged ; Pleura/metabolism ; Pleura/pathology ; Pleural Neoplasms/metabolism ; Pleural Neoplasms/pathology ; Sensitivity and Specificity
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
NCOA3-mediated upregulation of mucin expression via transcriptional and post-translational changes during the development of pancreatic cancer.
Autorzy:
Kumar S; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA.
Das S; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA.
Rachagani S; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA.
Kaur S; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA.
Joshi S; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA.
Johansson SL; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE, USA.
Ponnusamy MP; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA.
Jain M; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA.; Fred and Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, NE, USA.
Batra SK; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA.; Fred and Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, NE, USA.; Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, NE, USA.
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Źródło:
Oncogene [Oncogene] 2015 Sep 10; Vol. 34 (37), pp. 4879-89. Date of Electronic Publication: 2014 Dec 22.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Mucin-1*/genetics
Mucin-1*/metabolism
Mucin-4*/genetics
Mucin-4*/metabolism
Nuclear Receptor Coactivator 3/*physiology
Pancreatic Neoplasms/*genetics
Pancreatic Neoplasms/*metabolism
Protein Processing, Post-Translational/*genetics
Animals ; Cell Transformation, Neoplastic/genetics ; Fucose/metabolism ; Fucosyltransferases/metabolism ; Gene Expression Profiling ; Gene Expression Regulation, Neoplastic ; Humans ; Mice ; Microarray Analysis ; Pancreatic Neoplasms/pathology ; Transcriptional Activation ; Tumor Cells, Cultured ; Up-Regulation/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Bile accelerates carcinogenic processes in pancreatic ductal adenocarcinoma cells through the overexpression of MUC4.
Autorzy:
Gál E; Department of Pharmacology and Pharmacotherapy, University of Szeged, 6720, Szeged, Hungary.
Veréb Z; Regenerative Medicine and Cellular Pharmacology Research Laboratory, Department of Dermatology and Allergology, University of Szeged, Szeged, Hungary.; HCEMM SZTE Skin Research Group, University of Szeged, Szeged, Hungary.
Kemény L; Regenerative Medicine and Cellular Pharmacology Research Laboratory, Department of Dermatology and Allergology, University of Szeged, Szeged, Hungary.; HCEMM SZTE Skin Research Group, University of Szeged, Szeged, Hungary.
Rakk D; Department of Microbiology, University of Szeged, Szeged, Hungary.
Szekeres A; Department of Microbiology, University of Szeged, Szeged, Hungary.
Becskeházi E; Department of Pharmacology and Pharmacotherapy, University of Szeged, 6720, Szeged, Hungary.
Tiszlavicz L; Department of Pathology, University of Szeged, Szeged, Hungary.
Takács T; First Department of Medicine, University of Szeged, Szeged, Hungary.
Czakó L; First Department of Medicine, University of Szeged, Szeged, Hungary.
Hegyi P; First Department of Medicine, University of Szeged, Szeged, Hungary.; Institute for Translational Medicine, Medical School, Szentágothai Research Centre, University of Pécs, Pécs, Hungary.; Division of Gastroenterology, First Department of Medicine, Medical School, University of Pécs, Pécs, Hungary.
Venglovecz V; Department of Pharmacology and Pharmacotherapy, University of Szeged, 6720, Szeged, Hungary. .
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Źródło:
Scientific reports [Sci Rep] 2020 Dec 16; Vol. 10 (1), pp. 22088. Date of Electronic Publication: 2020 Dec 16.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Adenocarcinoma/*genetics
Carcinogenesis/*genetics
Carcinogens/*toxicity
Carcinoma, Pancreatic Ductal/*genetics
Mucin-4/*genetics
Adenocarcinoma/chemically induced ; Adenocarcinoma/pathology ; Adult ; Aged ; Bile/drug effects ; Carcinogenesis/drug effects ; Carcinoma, Pancreatic Ductal/chemically induced ; Carcinoma, Pancreatic Ductal/pathology ; Cell Line, Tumor ; Cell Movement/drug effects ; Cell Proliferation/drug effects ; Female ; Gene Expression Regulation, Neoplastic/drug effects ; Humans ; Male ; Middle Aged
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Transcriptome analysis reveals mucin 4 to be highly associated with periodontitis and identifies pleckstrin as a link to systemic diseases.
Autorzy:
Lundmark A; Department of Dental Medicine, Division of Periodontology, Karolinska Institutet, SE-141 04 Huddinge, Sweden.
Davanian H; Department of Dental Medicine, Division of Periodontology, Karolinska Institutet, SE-141 04 Huddinge, Sweden.
Båge T; Department of Dental Medicine, Division of Periodontology, Karolinska Institutet, SE-141 04 Huddinge, Sweden.
Johannsen G; Department of Dental Medicine, Division of Periodontology, Karolinska Institutet, SE-141 04 Huddinge, Sweden.
Koro C; Department of Dental Medicine, Division of Periodontology, Karolinska Institutet, SE-141 04 Huddinge, Sweden.
Lundeberg J; KTH Royal Institute of Technology, Science for Life Laboratory, School of Biotechnology, Division of Gene Technology, SE-171 65 Solna, Sweden.
Yucel-Lindberg T; Department of Dental Medicine, Division of Periodontology, Karolinska Institutet, SE-141 04 Huddinge, Sweden.
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Źródło:
Scientific reports [Sci Rep] 2015 Dec 21; Vol. 5, pp. 18475. Date of Electronic Publication: 2015 Dec 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Blood Proteins/*biosynthesis
Mucin-4/*biosynthesis
Periodontitis/*genetics
Phosphoproteins/*biosynthesis
Transcriptome/*genetics
Adult ; Aged ; Arthritis, Rheumatoid/genetics ; Arthritis, Rheumatoid/pathology ; Blood Proteins/genetics ; Cardiovascular Diseases/genetics ; Cardiovascular Diseases/pathology ; Colitis, Ulcerative/genetics ; Colitis, Ulcerative/pathology ; Female ; Gene Expression Profiling ; Gene Expression Regulation ; Humans ; Male ; Middle Aged ; Mucin-4/genetics ; Periodontitis/pathology ; Phosphoproteins/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Altered mucins and aquaporins indicate dry eye outcome in patients undergoing Vitreo-retinal surgery.
Autorzy:
Mani R; RS Mehta Jain Department of Biochemistry and Cell Biology, Vision Research Foundation, SankaraNethralaya, Chennai, India.
Shobha PS; Elite School of Optometry, Medical Research Foundation, SankaraNethralaya, Chennai, India.
Thilagavathi S; Elite School of Optometry, Medical Research Foundation, SankaraNethralaya, Chennai, India.
Prema P; Department of Cornea and Refractive Surgery, Medical Research Foundation, SankaraNethralaya, Chennai, India.
Viswanathan N; Department of Bio-Statistics, Vision Research Foundation, SankaraNethralaya, Chennai, India.
Vineet R; Department of Comprehensive Ophthalmology, Medical Research Foundation, SankaraNethralaya, Chennai, India.
Dhanashree R; Department of Vitreo-retinal Diseases, Medical Research Foundation, SankaraNethralaya, Chennai, India.
Angayarkanni N; RS Mehta Jain Department of Biochemistry and Cell Biology, Vision Research Foundation, SankaraNethralaya, Chennai, India.
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Źródło:
PloS one [PLoS One] 2020 May 21; Vol. 15 (5), pp. e0233517. Date of Electronic Publication: 2020 May 21 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Aquaporins/*genetics
Dry Eye Syndromes/*surgery
Mucins/*genetics
Aquaporin 4/analysis ; Aquaporin 4/genetics ; Aquaporin 5/analysis ; Aquaporin 5/genetics ; Aquaporins/analysis ; CA-125 Antigen/analysis ; CA-125 Antigen/genetics ; Conjunctiva/chemistry ; Conjunctiva/metabolism ; Conjunctiva/pathology ; Dry Eye Syndromes/genetics ; Dry Eye Syndromes/pathology ; Female ; Gene Expression ; Humans ; Male ; Membrane Proteins/analysis ; Membrane Proteins/genetics ; Middle Aged ; Mucin 5AC/analysis ; Mucin 5AC/genetics ; Mucin-4/analysis ; Mucin-4/genetics ; Mucins/analysis ; Tears/chemistry ; Tears/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 1-20 z 137

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