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Tytuł:
A metabolomics comparison of plant-based meat and grass-fed meat indicates large nutritional differences despite comparable Nutrition Facts panels.
Autorzy:
van Vliet S; Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC, USA. .
Bain JR; Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC, USA.
Muehlbauer MJ; Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC, USA.
Provenza FD; Department of Wildland Resources, Utah State University, Logan, UT, USA.
Kronberg SL; Northern Great Plains Research Laboratory, USDA-Agricultural Research Service, Mandan, ND, USA.
Pieper CF; Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC, USA.
Huffman KM; Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC, USA.
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Źródło:
Scientific reports [Sci Rep] 2021 Jul 05; Vol. 11 (1), pp. 13828. Date of Electronic Publication: 2021 Jul 05.
Typ publikacji:
Journal Article
MeSH Terms:
Metabolomics*
Taste*
Meat/*analysis
Nutrients/*metabolism
Animal Feed ; Animals ; Anserine/metabolism ; Antioxidants/metabolism ; Cattle ; Fatty Acids/isolation & purification ; Fatty Acids/metabolism ; Fatty Acids, Omega-3/isolation & purification ; Fatty Acids, Omega-3/metabolism ; Humans ; Nutrients/isolation & purification ; Nutritional Status ; Nutritive Value ; Red Meat/analysis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Disrupted Maturation of the Microbiota and Metabolome among Extremely Preterm Infants with Postnatal Growth Failure.
Autorzy:
Younge NE; Division of Neonatology, Department of Pediatrics, Duke University, Durham, NC, 27710, USA. .
Newgard CB; Duke Molecular Physiology Institute and Sarah W. Stedman Nutrition and Metabolism Center, Duke University, Durham, NC, 27701, USA.; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, 27710, USA.; Division of Endocrinology and Metabolism, Department of Medicine, Duke University, Durham, NC, 27710, USA.
Cotten CM; Division of Neonatology, Department of Pediatrics, Duke University, Durham, NC, 27710, USA.
Goldberg RN; Division of Neonatology, Department of Pediatrics, Duke University, Durham, NC, 27710, USA.
Muehlbauer MJ; Duke Molecular Physiology Institute and Sarah W. Stedman Nutrition and Metabolism Center, Duke University, Durham, NC, 27701, USA.
Bain JR; Duke Molecular Physiology Institute and Sarah W. Stedman Nutrition and Metabolism Center, Duke University, Durham, NC, 27701, USA.; Division of Endocrinology and Metabolism, Department of Medicine, Duke University, Durham, NC, 27710, USA.
Stevens RD; Duke Molecular Physiology Institute and Sarah W. Stedman Nutrition and Metabolism Center, Duke University, Durham, NC, 27701, USA.; Division of Endocrinology and Metabolism, Department of Medicine, Duke University, Durham, NC, 27710, USA.
O'Connell TM; Duke Molecular Physiology Institute and Sarah W. Stedman Nutrition and Metabolism Center, Duke University, Durham, NC, 27701, USA.; Department of Otolaryngology, Head and Neck Surgery, Indiana University, Indianapolis, IN, 46202, USA.
Rawls JF; Department of Molecular Genetics and Microbiology, Duke University, Durham, NC, 27710, USA.
Seed PC; Department of Pediatrics, Northwestern University, Chicago, IL, 60611, USA.
Ashley PL; Division of Neonatology, Department of Pediatrics, Duke University, Durham, NC, 27710, USA.
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Źródło:
Scientific reports [Sci Rep] 2019 Jun 03; Vol. 9 (1), pp. 8167. Date of Electronic Publication: 2019 Jun 03.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Metabolomics*
Bacteria/*genetics
Gastrointestinal Microbiome/*genetics
Infant, Extremely Premature/*growth & development
Adult ; Bacteria/classification ; Bacteria/isolation & purification ; Enterobacteriaceae/genetics ; Enterobacteriaceae/isolation & purification ; Feces/microbiology ; Female ; Gestational Age ; Humans ; Infant ; Infant, Extremely Premature/metabolism ; Infant, Newborn ; Male ; Metabolome/genetics ; Pregnancy ; RNA, Ribosomal, 16S/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Effects of the kinase inhibitor sorafenib on heart, muscle, liver and plasma metabolism in vivo using non-targeted metabolomics analysis.
Autorzy:
Jensen BC; McAllister Heart Institute, University of North Carolina, Chapel Hill, NC, USA.; Department of Internal Medicine, Division of Cardiology University of North Carolina, Chapel Hill, NC, USA.; Department of Pharmacology, University of North Carolina, Chapel Hill, NC, USA.
Parry TL; McAllister Heart Institute, University of North Carolina, Chapel Hill, NC, USA.; Department of Pathology & Laboratory Medicine, University of North Carolina, Chapel Hill, NC, USA.
Huang W; McAllister Heart Institute, University of North Carolina, Chapel Hill, NC, USA.
Beak JY; McAllister Heart Institute, University of North Carolina, Chapel Hill, NC, USA.
Ilaiwy A; Sarah W. Stedman Nutrition and Metabolism Center, Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC, USA.; Division of Endocrinology, Metabolism, and Nutrition, Department of Medicine, Duke University Medical Center, Durham, NC, USA.
Bain JR; Sarah W. Stedman Nutrition and Metabolism Center, Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC, USA.; Division of Endocrinology, Metabolism, and Nutrition, Department of Medicine, Duke University Medical Center, Durham, NC, USA.
Newgard CB; Sarah W. Stedman Nutrition and Metabolism Center, Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC, USA.; Division of Endocrinology, Metabolism, and Nutrition, Department of Medicine, Duke University Medical Center, Durham, NC, USA.
Muehlbauer MJ; Sarah W. Stedman Nutrition and Metabolism Center, Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC, USA.
Patterson C; Presbyterian Hospital/Weill-Cornell Medical Center, New York, NY, USA.
Johnson GL; Department of Pharmacology, University of North Carolina, Chapel Hill, NC, USA.
Willis MS; McAllister Heart Institute, University of North Carolina, Chapel Hill, NC, USA.; Department of Pathology & Laboratory Medicine, University of North Carolina, Chapel Hill, NC, USA.; Department of Pharmacology, University of North Carolina, Chapel Hill, NC, USA.
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Źródło:
British journal of pharmacology [Br J Pharmacol] 2017 Dec; Vol. 174 (24), pp. 4797-4811. Date of Electronic Publication: 2017 Nov 24.
Typ publikacji:
Journal Article
MeSH Terms:
Metabolomics*
Heart/*drug effects
Liver/*drug effects
Muscle, Skeletal/*drug effects
Niacinamide/*analogs & derivatives
Phenylurea Compounds/*pharmacology
Plasma/*drug effects
Protein Kinase Inhibitors/*pharmacology
Animals ; Liver/metabolism ; Mice ; Mice, Inbred Strains ; Muscle, Skeletal/metabolism ; Niacinamide/chemistry ; Niacinamide/pharmacology ; Phenylurea Compounds/chemistry ; Plasma/metabolism ; Protein Kinase Inhibitors/chemistry ; Sorafenib ; Tissue Distribution
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Mixture model normalization for non-targeted gas chromatography/mass spectrometry metabolomics data.
Autorzy:
Reisetter AC; Department of Preventive Medicine, Division of Biostatistics, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA.
Muehlbauer MJ; Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, NC, 27701, USA.; Duke University School of Medicine, Durham, NC, 27701, USA.
Bain JR; Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, NC, 27701, USA.; Duke University School of Medicine, Durham, NC, 27701, USA.
Nodzenski M; Department of Preventive Medicine, Division of Biostatistics, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA.
Stevens RD; Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, NC, 27701, USA.; Duke University School of Medicine, Durham, NC, 27701, USA.
Ilkayeva O; Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, NC, 27701, USA.; Duke University School of Medicine, Durham, NC, 27701, USA.
Metzger BE; Department of Medicine, Division of Endocrinology, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA.
Newgard CB; Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, NC, 27701, USA.; Duke University School of Medicine, Durham, NC, 27701, USA.
Lowe WL Jr; Department of Medicine, Division of Endocrinology, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA.
Scholtens DM; Department of Preventive Medicine, Division of Biostatistics, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA. .
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Źródło:
BMC bioinformatics [BMC Bioinformatics] 2017 Feb 02; Vol. 18 (1), pp. 84. Date of Electronic Publication: 2017 Feb 02.
Typ publikacji:
Journal Article
MeSH Terms:
Gas Chromatography-Mass Spectrometry/*methods
Metabolomics/*methods
Female ; Gas Chromatography-Mass Spectrometry/standards ; Humans ; Infant, Newborn ; Metabolomics/standards ; Models, Biological ; Pregnancy ; Quality Control
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Metabolomic profiling reveals mitochondrial-derived lipid biomarkers that drive obesity-associated inflammation.
Autorzy:
Sampey BP; Department of Nutrition, Gillings School of Global Public Health, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
Freemerman AJ
Zhang J
Kuan PF
Galanko JA
O'Connell TM
Ilkayeva OR
Muehlbauer MJ
Stevens RD
Newgard CB
Brauer HA
Troester MA
Makowski L
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Źródło:
PloS one [PLoS One] 2012; Vol. 7 (6), pp. e38812. Date of Electronic Publication: 2012 Jun 12.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Diet*
Biomarkers/*metabolism
Inflammation/*metabolism
Metabolic Syndrome/*metabolism
Metabolomics/*methods
Mitochondria/*metabolism
Obesity/*complications
Adipose Tissue/metabolism ; Amino Acids/blood ; Amino Acids/metabolism ; Analysis of Variance ; Animals ; Blotting, Western ; Carnitine/analogs & derivatives ; Carnitine/blood ; Carnitine/metabolism ; Carnitine/pharmacology ; Chromatography, Liquid ; Cluster Analysis ; Computational Biology ; Fatty Acids/metabolism ; Gene Expression Regulation/drug effects ; Inflammation/etiology ; Laurates/pharmacology ; Macrophages/drug effects ; Metabolic Syndrome/etiology ; Principal Component Analysis ; Rats ; Tandem Mass Spectrometry
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Metabolomic and genetic architecture of gestational diabetes subtypes
Autorzy:
Lee, Kristen
Kuang, Alan
Bain, James R.Aff3, Aff4
Hayes, M. Geoffrey
Muehlbauer, Michael J.
Ilkayeva, Olga R.Aff3, Aff4
Newgard, Christopher B.Aff3, Aff4
Powe, Camille E.Aff5, Aff6, Aff7
Hivert, Marie-FranceAff5, Aff8, Aff9, Aff10
Scholtens, Denise M.
Lowe, Jr, William L.Aff1, IDs0012502406110x_cor11
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Źródło:
Diabetologia: Clinical, Translational and Experimental Diabetes and Metabolism. 67(5):895-907
Czasopismo naukowe
Szczegóły
Tytuł:
Maternal metabolites during pregnancy are associated with newborn outcomes and hyperinsulinaemia across ancestries
Autorzy:
Kadakia, RachelAff1, Aff2
Nodzenski, Michael
Talbot, Octavious
Kuang, Alan
Bain, James R.Aff3, Aff4, Aff5
Muehlbauer, Michael J.Aff3, Aff4, Aff5
Stevens, Robert D.Aff3, Aff4, Aff5
Ilkayeva, Olga R.Aff3, Aff4, Aff5
O’Neal, Sara K.Aff3, Aff4, Aff5
Lowe, Lynn P.
Metzger, Boyd E.
Newgard, Christopher B.Aff3, Aff4, Aff5
Scholtens, Denise M.
Lowe, Jr, William L.
for the HAPO Study Cooperative Research Group
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Źródło:
Diabetologia: Clinical, Translational and Experimental Diabetes and Metabolism. 62(3):473-484
Czasopismo naukowe
Szczegóły
Tytuł:
Human amylin proteotoxicity impairs protein biosynthesis, and alters major cellular signaling pathways in the heart, brain and liver of humanized diabetic rat model in vivo
Autorzy:
Ilaiwy, Amro
Liu, Miao
Parry, Traci L.
Bain, James R.
Newgard, Christopher B.
Schisler, Jonathan C.
Muehlbauer, Michael J.
Despa, Florin
Willis, Monte S.
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Źródło:
Metabolomics: An Official Journal of the Metabolomics Society. May 2016 12(5):1-14
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Non-targeted metabolomics of Brg1/Brm double-mutant cardiomyocytes reveals a novel role for SWI/SNF complexes in metabolic homeostasis
Autorzy:
Banerjee, Ranjan
Bultman, Scott J.
Holley, Darcy
Hillhouse, Carolyn
Bain, James R.
Newgard, Christopher B.
Muehlbauer, Michael J.
Willis, Monte S.
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Źródło:
Metabolomics: An Official Journal of the Metabolomics Society. October 2015 11(5):1287-1301
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Impact of combined resistance and aerobic exercise training on branched-chain amino acid turnover, glycine metabolism and insulin sensitivity in overweight humans
Autorzy:
Glynn, Erin L.
Piner, Lucy W.
Huffman, Kim M.
Slentz, Cris A.
Elliot-Penry, Lorraine
AbouAssi, Hiba
White, Phillip J.
Bain, James R.
Muehlbauer, Michael J.
Ilkayeva, Olga R.
Stevens, Robert D.
Porter Starr, Kathryn N.
Bales, Connie W.
Volpi, Elena
Brosnan, M. Julia
Trimmer, Jeff K.
Rolph, Timothy P.
Newgard, Christopher B.
Kraus, William E.
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Źródło:
Diabetologia: Clinical and Experimental Diabetes and Metabolism. October 2015 58(10):2324-2335
Czasopismo naukowe
Szczegóły
Tytuł:
Non-targeted metabolomics analysis of cardiac Muscle Ring Finger-1 (MuRF1), MuRF2, and MuRF3 in vivo reveals novel and redundant metabolic changes
Autorzy:
Banerjee, Ranjan
He, Jun
Spaniel, Carolyn
Quintana, Megan T.
Wang, Zhongjing
Bain, James R.
Newgard, Christopher B.
Muehlbauer, Michael J.
Willis, Monte S.
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Źródło:
Metabolomics: An Official Journal of the Metabolomics Society. April 2015 11(2):312-322
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Wyświetlanie 1-20 z 67

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