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Tytuł :
Effect of Mechanical Properties on Multicomponent Shell Patterning.
Autorzy :
Li S; Department of Materials Science and Engineering, Northwestern University, Evanston, Illinois 60208, United States.; Department of Physics and Astronomy, Northwestern University, Evanston, Illinois 60208, United States.
Matoz-Fernandez DA; Department of Materials Science and Engineering, Northwestern University, Evanston, Illinois 60208, United States.; Department of Physics and Astronomy, Northwestern University, Evanston, Illinois 60208, United States.
Olvera de la Cruz M; Department of Materials Science and Engineering, Northwestern University, Evanston, Illinois 60208, United States.; Department of Physics and Astronomy, Northwestern University, Evanston, Illinois 60208, United States.; Department of Chemistry, Northwestern University, Evanston, Illinois 60208, United States.
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Źródło :
ACS nano [ACS Nano] 2021 Sep 28; Vol. 15 (9), pp. 14804-14812. Date of Electronic Publication: 2021 Aug 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Cell Compartmentation*
Multiprotein Complexes*
Bacteria ; Bacterial Proteins ; Gene Expression Regulation, Bacterial ; Genomics
Czasopismo naukowe
Tytuł :
Identification of Tse8 as a Type VI secretion system toxin from Pseudomonas aeruginosa that targets the bacterial transamidosome to inhibit protein synthesis in prey cells.
Autorzy :
Nolan LM; MRC Centre for Molecular Bacteriology and Infection (CMBI), Department of Life Sciences, Imperial College London, London, UK.; National Heart and Lung Institute, Imperial College London, London, UK.
Cain AK; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge, UK.; Department of Molecular Sciences, Macquarie University, Sydney, NSW, Australia.
Clamens T; MRC Centre for Molecular Bacteriology and Infection (CMBI), Department of Life Sciences, Imperial College London, London, UK.
Furniss RCD; MRC Centre for Molecular Bacteriology and Infection (CMBI), Department of Life Sciences, Imperial College London, London, UK.; Science for Life Laboratory, Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, Stockholm, Sweden.
Manoli E; MRC Centre for Molecular Bacteriology and Infection (CMBI), Department of Life Sciences, Imperial College London, London, UK.
Sainz-Polo MA; Structural Biology Unit, CIC bioGUNE, Bizkaia Technology Park, Derio, Spain.
Dougan G; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge, UK.
Albesa-Jové D; Structural Biology Unit, CIC bioGUNE, Bizkaia Technology Park, Derio, Spain.; IKERBASQUE, Basque Foundation for Science, Bilbao, Spain.; Instituto Biofisika (UPV/EHU, CSIC), Fundación Biofísica Bizkaia/Biofisika Bizkaia Fundazioa (FBB) and Departamento de Bioquímica y Biología Molecular, University of the Basque Country, Leioa, Spain.
Parkhill J; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge, UK.; Department of Veterinary Medicine, University of Cambridge, Cambridge, UK.
Mavridou DAI; MRC Centre for Molecular Bacteriology and Infection (CMBI), Department of Life Sciences, Imperial College London, London, UK. .; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX, USA. .
Filloux A; MRC Centre for Molecular Bacteriology and Infection (CMBI), Department of Life Sciences, Imperial College London, London, UK. .
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Źródło :
Nature microbiology [Nat Microbiol] 2021 Sep; Vol. 6 (9), pp. 1199-1210. Date of Electronic Publication: 2021 Aug 19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Protein Biosynthesis*
Bacterial Proteins/*metabolism
Bacterial Toxins/*metabolism
Multiprotein Complexes/*metabolism
Pseudomonas aeruginosa/*genetics
Pseudomonas aeruginosa/*metabolism
Type VI Secretion Systems/*metabolism
Bacterial Proteins/genetics ; Multiprotein Complexes/genetics ; Protein Binding ; Type VI Secretion Systems/genetics
Czasopismo naukowe
Tytuł :
Strategy for high-throughput identification of protein complexes by array-based multi-dimensional liquid chromatography-mass spectrometry.
Autorzy :
Wang X; Department of Chemistry, Fudan University, Shanghai 200433, China.
Yan G; Department of Chemistry, Fudan University, Shanghai 200433, China; Department of Chemistry and Institutes of Biomedical Sciences, Fudan University, Shanghai 200433, China.
Zheng H; Department of Chemistry, Fudan University, Shanghai 200433, China.
Gao M; Department of Chemistry, Fudan University, Shanghai 200433, China. Electronic address: .
Zhang X; Department of Chemistry, Fudan University, Shanghai 200433, China. Electronic address: .
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Źródło :
Journal of chromatography. A [J Chromatogr A] 2021 Aug 30; Vol. 1652, pp. 462351. Date of Electronic Publication: 2021 Jun 15.
Typ publikacji :
Journal Article
MeSH Terms :
Chromatography, Liquid/*methods
Multiprotein Complexes/*analysis
Tandem Mass Spectrometry/*methods
HeLa Cells ; Humans ; Multiprotein Complexes/isolation & purification ; Protein Interaction Mapping
Czasopismo naukowe
Tytuł :
Cryo-EM of NHEJ supercomplexes provides insights into DNA repair.
Autorzy :
Chaplin AK; Department of Biochemistry, University of Cambridge, Sanger Building, Tennis Court Road, Cambridge CB2 1GA, UK. Electronic address: .
Hardwick SW; CryoEM Facility, Department of Biochemistry, University of Cambridge, Sanger Building, Tennis Court Road, Cambridge CB2 1GA, UK.
Stavridi AK; Department of Biochemistry, University of Cambridge, Sanger Building, Tennis Court Road, Cambridge CB2 1GA, UK.
Buehl CJ; College of Veterinary Medicine, Department of Microbiology & Molecular Genetics, Department of Pathobiology & Diagnostic Investigation, Michigan State University, East Lansing, MI 48824, USA.
Goff NJ; College of Veterinary Medicine, Department of Microbiology & Molecular Genetics, Department of Pathobiology & Diagnostic Investigation, Michigan State University, East Lansing, MI 48824, USA.
Ropars V; Institute for Integrative Biology of the Cell (I2BC), Institute Joliot, CEA, CNRS, Université Paris-Saclay, 91198, Gif-sur-Yvette Cedex, France.
Liang S; Department of Biochemistry, University of Cambridge, Sanger Building, Tennis Court Road, Cambridge CB2 1GA, UK.
De Oliveira TM; AstraZeneca R&D, Discovery Sciences, Mechanistic and Structural Biology, Cambridge, UK.
Chirgadze DY; CryoEM Facility, Department of Biochemistry, University of Cambridge, Sanger Building, Tennis Court Road, Cambridge CB2 1GA, UK.
Meek K; College of Veterinary Medicine, Department of Microbiology & Molecular Genetics, Department of Pathobiology & Diagnostic Investigation, Michigan State University, East Lansing, MI 48824, USA.
Charbonnier JB; Institute for Integrative Biology of the Cell (I2BC), Institute Joliot, CEA, CNRS, Université Paris-Saclay, 91198, Gif-sur-Yvette Cedex, France.
Blundell TL; Department of Biochemistry, University of Cambridge, Sanger Building, Tennis Court Road, Cambridge CB2 1GA, UK. Electronic address: .
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Źródło :
Molecular cell [Mol Cell] 2021 Aug 19; Vol. 81 (16), pp. 3400-3409.e3. Date of Electronic Publication: 2021 Aug 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA Ligase ATP/*ultrastructure
DNA Repair Enzymes/*ultrastructure
DNA-Activated Protein Kinase/*ultrastructure
DNA-Binding Proteins/*ultrastructure
Multiprotein Complexes/*ultrastructure
Apoptosis/genetics ; Cryoelectron Microscopy ; DNA Breaks, Double-Stranded ; DNA Damage/genetics ; DNA End-Joining Repair/genetics ; DNA Ligase ATP/genetics ; DNA Repair/genetics ; DNA Repair Enzymes/genetics ; DNA-Activated Protein Kinase/genetics ; DNA-Binding Proteins/genetics ; Humans ; Ku Autoantigen/genetics ; Ku Autoantigen/ultrastructure ; Multiprotein Complexes/genetics ; Phosphorylation/genetics
Czasopismo naukowe
Tytuł :
Structural basis of complex formation between mitochondrial anion channel VDAC1 and Hexokinase-II.
Autorzy :
Haloi N; Theoretical and Computational Biophysics Group, NIH Center for Macromolecular Modeling and Bioinformatics, Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, IL, USA.; Department of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, IL, USA.; Center for Biophysics and Quantitative Biology, University of Illinois at Urbana-Champaign, Urbana, IL, USA.
Wen PC; Theoretical and Computational Biophysics Group, NIH Center for Macromolecular Modeling and Bioinformatics, Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, IL, USA.; Department of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, IL, USA.; Center for Biophysics and Quantitative Biology, University of Illinois at Urbana-Champaign, Urbana, IL, USA.
Cheng Q; Department of Anesthesiology, Medical College of Wisconsin, Milwaukee, WI, USA.
Yang M; Department of Anesthesiology, Medical College of Wisconsin, Milwaukee, WI, USA.
Natarajan G; Department of Anesthesiology, Medical College of Wisconsin, Milwaukee, WI, USA.
Camara AKS; Department of Anesthesiology, Medical College of Wisconsin, Milwaukee, WI, USA.; Department of Physiology, Medical College of Wisconsin, Milwaukee, WI, USA.; Cancer Center and Cardiovascular Center, Medical College of Wisconsin, Milwaukee, WI, USA.
Kwok WM; Department of Anesthesiology, Medical College of Wisconsin, Milwaukee, WI, USA. .; Cancer Center and Cardiovascular Center, Medical College of Wisconsin, Milwaukee, WI, USA. .; Department of Pharmacology & Toxicology, Medical College of Wisconsin, Milwaukee, WI, USA. .
Tajkhorshid E; Theoretical and Computational Biophysics Group, NIH Center for Macromolecular Modeling and Bioinformatics, Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, IL, USA. .; Department of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, IL, USA. .; Center for Biophysics and Quantitative Biology, University of Illinois at Urbana-Champaign, Urbana, IL, USA. .
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Źródło :
Communications biology [Commun Biol] 2021 Jun 03; Vol. 4 (1), pp. 667. Date of Electronic Publication: 2021 Jun 03.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Molecular Dynamics Simulation*
Hexokinase/*metabolism
Mitochondrial Proteins/*metabolism
Multiprotein Complexes/*metabolism
Voltage-Dependent Anion Channel 1/*metabolism
Binding Sites ; Crystallography, X-Ray ; Hexokinase/chemistry ; Hexokinase/genetics ; Humans ; Mitochondrial Membranes/metabolism ; Mitochondrial Proteins/chemistry ; Mitochondrial Proteins/genetics ; Multiprotein Complexes/chemistry ; Multiprotein Complexes/genetics ; Mutation ; Protein Binding ; Protein Domains ; Voltage-Dependent Anion Channel 1/chemistry ; Voltage-Dependent Anion Channel 1/genetics
Czasopismo naukowe
Tytuł :
Structural insights into the multivalent binding of the Arabidopsis FLOWERING LOCUS T promoter by the CO-NF-Y master transcription factor complex.
Autorzy :
Lv X; National Key Laboratory of Plant Molecular Genetics and Shanghai Center for Plant Stress Biology, CAS Center for Excellence in Molecular Plant Sciences, Chinese Academy of Sciences, Shanghai 201602, China.; Key Laboratory of Molecular Design for Plant Cell Factory of Guangdong Higher Education Institutes, School of Life Sciences, Institute of Plant and Food Science, Southern University of Science and Technology, Shenzhen 518055, China.; University of Chinese Academy of Sciences, Beijing 100049, China.
Zeng X; National Key Laboratory of Plant Molecular Genetics and Shanghai Center for Plant Stress Biology, CAS Center for Excellence in Molecular Plant Sciences, Chinese Academy of Sciences, Shanghai 201602, China.
Hu H; National Key Laboratory of Plant Molecular Genetics and Shanghai Center for Plant Stress Biology, CAS Center for Excellence in Molecular Plant Sciences, Chinese Academy of Sciences, Shanghai 201602, China.; Key Laboratory of Molecular Design for Plant Cell Factory of Guangdong Higher Education Institutes, School of Life Sciences, Institute of Plant and Food Science, Southern University of Science and Technology, Shenzhen 518055, China.; University of Chinese Academy of Sciences, Beijing 100049, China.
Chen L; National Key Laboratory of Plant Molecular Genetics and Shanghai Center for Plant Stress Biology, CAS Center for Excellence in Molecular Plant Sciences, Chinese Academy of Sciences, Shanghai 201602, China.; University of Chinese Academy of Sciences, Beijing 100049, China.
Zhang F; Key Laboratory of Molecular Design for Plant Cell Factory of Guangdong Higher Education Institutes, School of Life Sciences, Institute of Plant and Food Science, Southern University of Science and Technology, Shenzhen 518055, China.
Liu R; Key Laboratory of Molecular Design for Plant Cell Factory of Guangdong Higher Education Institutes, School of Life Sciences, Institute of Plant and Food Science, Southern University of Science and Technology, Shenzhen 518055, China.
Liu Y; Key Laboratory of Molecular Design for Plant Cell Factory of Guangdong Higher Education Institutes, School of Life Sciences, Institute of Plant and Food Science, Southern University of Science and Technology, Shenzhen 518055, China.
Zhou X; National Key Laboratory of Plant Molecular Genetics and Shanghai Center for Plant Stress Biology, CAS Center for Excellence in Molecular Plant Sciences, Chinese Academy of Sciences, Shanghai 201602, China.; Key Laboratory of Molecular Design for Plant Cell Factory of Guangdong Higher Education Institutes, School of Life Sciences, Institute of Plant and Food Science, Southern University of Science and Technology, Shenzhen 518055, China.; University of Chinese Academy of Sciences, Beijing 100049, China.
Wang C; Key Laboratory of Molecular Design for Plant Cell Factory of Guangdong Higher Education Institutes, School of Life Sciences, Institute of Plant and Food Science, Southern University of Science and Technology, Shenzhen 518055, China.
Wu Z; Key Laboratory of Molecular Design for Plant Cell Factory of Guangdong Higher Education Institutes, School of Life Sciences, Institute of Plant and Food Science, Southern University of Science and Technology, Shenzhen 518055, China.
Kim C; National Key Laboratory of Plant Molecular Genetics and Shanghai Center for Plant Stress Biology, CAS Center for Excellence in Molecular Plant Sciences, Chinese Academy of Sciences, Shanghai 201602, China.
He Y; National Key Laboratory of Plant Molecular Genetics and Shanghai Center for Plant Stress Biology, CAS Center for Excellence in Molecular Plant Sciences, Chinese Academy of Sciences, Shanghai 201602, China.
Du J; Key Laboratory of Molecular Design for Plant Cell Factory of Guangdong Higher Education Institutes, School of Life Sciences, Institute of Plant and Food Science, Southern University of Science and Technology, Shenzhen 518055, China.
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Źródło :
The Plant cell [Plant Cell] 2021 May 31; Vol. 33 (4), pp. 1182-1195.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Arabidopsis/*metabolism
Arabidopsis Proteins/*chemistry
Arabidopsis Proteins/*genetics
Arabidopsis Proteins/*metabolism
DNA-Binding Proteins/*chemistry
DNA-Binding Proteins/*metabolism
Multiprotein Complexes/*metabolism
Transcription Factors/*chemistry
Transcription Factors/*metabolism
Arabidopsis/genetics ; Binding Sites ; Crystallography, X-Ray ; DNA-Binding Proteins/genetics ; Gene Expression Regulation, Plant ; Multiprotein Complexes/chemistry ; Multiprotein Complexes/genetics ; Promoter Regions, Genetic ; Protein Domains ; Trans-Activators/chemistry ; Trans-Activators/genetics ; Trans-Activators/metabolism ; Transcription Factors/genetics
Czasopismo naukowe
Tytuł :
3D genomics across the tree of life reveals condensin II as a determinant of architecture type.
Autorzy :
Hoencamp C; Division of Gene Regulation, Netherlands Cancer Institute, 1066 CX Amsterdam, Netherlands.
Dudchenko O; The Center for Genome Architecture, Baylor College of Medicine, Houston, TX 77030, USA.; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.; Center for Theoretical Biological Physics, Rice University, Houston, TX 77005, USA.
Elbatsh AMO; Division of Gene Regulation, Netherlands Cancer Institute, 1066 CX Amsterdam, Netherlands.
Brahmachari S; Center for Theoretical Biological Physics, Rice University, Houston, TX 77005, USA.
Raaijmakers JA; Division of Cell Biology, Oncode Institute, Netherlands Cancer Institute, 1066 CX Amsterdam, Netherlands.
van Schaik T; Division of Gene Regulation, Oncode Institute, Netherlands Cancer Institute, 1066 CX Amsterdam, Netherlands.
Sedeño Cacciatore Á; Division of Gene Regulation, Netherlands Cancer Institute, 1066 CX Amsterdam, Netherlands.
Contessoto VG; Center for Theoretical Biological Physics, Rice University, Houston, TX 77005, USA.; Department of Physics, Institute of Biosciences, Letters and Exact Sciences, São Paulo State University (UNESP), São José do Rio Preto - SP, 15054-000, Brazil.
van Heesbeen RGHP; Division of Cell Biology, Oncode Institute, Netherlands Cancer Institute, 1066 CX Amsterdam, Netherlands.
van den Broek B; BioImaging Facility, Netherlands Cancer Institute, 1066 CX Amsterdam, Netherlands.
Mhaskar AN; Division of Gene Regulation, Netherlands Cancer Institute, 1066 CX Amsterdam, Netherlands.
Teunissen H; Division of Gene Regulation, Oncode Institute, Netherlands Cancer Institute, 1066 CX Amsterdam, Netherlands.
St Hilaire BG; The Center for Genome Architecture, Baylor College of Medicine, Houston, TX 77030, USA.; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.
Weisz D; The Center for Genome Architecture, Baylor College of Medicine, Houston, TX 77030, USA.; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.
Omer AD; The Center for Genome Architecture, Baylor College of Medicine, Houston, TX 77030, USA.
Pham M; The Center for Genome Architecture, Baylor College of Medicine, Houston, TX 77030, USA.
Colaric Z; The Center for Genome Architecture, Baylor College of Medicine, Houston, TX 77030, USA.
Yang Z; Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech, Pudong 201210, China.
Rao SSP; The Center for Genome Architecture, Baylor College of Medicine, Houston, TX 77030, USA.; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.; Department of Structural Biology, Stanford University School of Medicine, Stanford, CA 94305, USA.
Mitra N; The Center for Genome Architecture, Baylor College of Medicine, Houston, TX 77030, USA.; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.
Lui C; The Center for Genome Architecture, Baylor College of Medicine, Houston, TX 77030, USA.
Yao W; The Center for Genome Architecture, Baylor College of Medicine, Houston, TX 77030, USA.
Khan R; The Center for Genome Architecture, Baylor College of Medicine, Houston, TX 77030, USA.; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.
Moroz LL; Whitney Laboratory and Department of Neuroscience, University of Florida, Gainesville, FL 32611, USA.
Kohn A; Whitney Laboratory and Department of Neuroscience, University of Florida, Gainesville, FL 32611, USA.
St Leger J; Department of Biosciences, Cornell University College of Veterinary Medicine, Ithaca, NY 14853, USA.
Mena A; SeaWorld San Diego, San Diego, CA 92109, USA.
Holcroft K; Moody Gardens, Galveston, TX 77554, USA.
Gambetta MC; Center for Integrative Genomics, University of Lausanne, 1015 Lausanne, Switzerland.
Lim F; Department of Medicine and Molecular Biology, University of California, San Diego, La Jolla, CA 92093, USA.
Farley E; Department of Medicine and Molecular Biology, University of California, San Diego, La Jolla, CA 92093, USA.
Stein N; Leibniz Institute of Plant Genetics and Crop Plant Research (IPK Gatersleben), 06466 Seeland, Germany.; Center of Integrated Breeding Research (CiBreed), Department of Crop Sciences, Georg-August-University Göttingen, 37075 Göttingen, Germany.; UWA School of Agriculture and Environment, The University of Western Australia, Perth, WA 6009, Australia.
Haddad A; The Center for Genome Architecture, Baylor College of Medicine, Houston, TX 77030, USA.
Chauss D; National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
Mutlu AS; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.
Wang MC; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.; Huffington Center on Aging, Baylor College of Medicine, Houston, TX 77030, USA.; Howard Hughes Medical Institute, Baylor College of Medicine, Houston, TX 77030, USA.
Young ND; Faculty of Veterinary and Agricultural Sciences, University of Melbourne, Parkville, VIC 3010, Australia.
Hildebrandt E; Avian Diseases and Oncology Laboratory, US Department of Agriculture, Agricultural Research Service, East Lansing, MI 48823, USA.
Cheng HH; Avian Diseases and Oncology Laboratory, US Department of Agriculture, Agricultural Research Service, East Lansing, MI 48823, USA.
Knight CJ; Hopkins Marine Station, Stanford University, Pacific Grove, CA 93950, USA.
Burnham TLU; Department of Wildlife, Fish, and Conservation Biology, University of California, Davis, Davis, CA 95616, USA.; Coastal and Marine Institute and Department of Biology, San Diego State University, San Diego, CA 92106, USA.
Hovel KA; Coastal and Marine Institute and Department of Biology, San Diego State University, San Diego, CA 92106, USA.
Beel AJ; Department of Structural Biology, Stanford University School of Medicine, Stanford, CA 94305, USA.
Mattei PJ; Department of Structural Biology, Stanford University School of Medicine, Stanford, CA 94305, USA.
Kornberg RD; Department of Structural Biology, Stanford University School of Medicine, Stanford, CA 94305, USA.
Warren WC; Department of Animal Sciences, University of Missouri, Columbia, MO 65211, USA.
Cary G; The Jackson Laboratory, Bar Harbor, ME 04609, USA.
Gómez-Skarmeta JL; Centro Andaluz de Biología del Desarrollo CSIC, Universidad Pablo de Olavide, 41013 Sevilla, Spain.
Hinman V; Department of Biological Sciences, Carnegie Mellon University, Pittsburgh, PA 15213, USA.
Lindblad-Toh K; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; Science for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University, 751 23 Uppsala, Sweden.
Di Palma F; Department of Biological Sciences, University of East Anglia, Norwich NR4 7TJ, UK.
Maeshima K; Genome Dynamics Laboratory, National Institute of Genetics, Mishima, Shizuoka 411-8540, Japan.; Department of Genetics, Sokendai (Graduate University for Advanced Studies), Mishima, Shizuoka 411-8540, Japan.
Multani AS; Department of Genetics, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Pathak S; Department of Genetics, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Nel-Themaat L; Department of Genetics, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Behringer RR; Department of Genetics, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Kaur P; UWA School of Agriculture and Environment, The University of Western Australia, Perth, WA 6009, Australia.
Medema RH; Division of Cell Biology, Oncode Institute, Netherlands Cancer Institute, 1066 CX Amsterdam, Netherlands.
van Steensel B; Division of Gene Regulation, Oncode Institute, Netherlands Cancer Institute, 1066 CX Amsterdam, Netherlands.
de Wit E; Division of Gene Regulation, Oncode Institute, Netherlands Cancer Institute, 1066 CX Amsterdam, Netherlands.
Onuchic JN; Center for Theoretical Biological Physics, Rice University, Houston, TX 77005, USA.; Departments of Physics and Astronomy, Chemistry, and Biosciences, Rice University, Houston, TX 77005, USA.
Di Pierro M; Center for Theoretical Biological Physics, Rice University, Houston, TX 77005, USA.; Department of Physics, Northeastern University, Boston, MA 02115, USA.
Lieberman Aiden E; The Center for Genome Architecture, Baylor College of Medicine, Houston, TX 77030, USA. .; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.; Center for Theoretical Biological Physics, Rice University, Houston, TX 77005, USA.; Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech, Pudong 201210, China.; UWA School of Agriculture and Environment, The University of Western Australia, Perth, WA 6009, Australia.; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Rowland BD; Division of Gene Regulation, Netherlands Cancer Institute, 1066 CX Amsterdam, Netherlands. .
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Źródło :
Science (New York, N.Y.) [Science] 2021 May 28; Vol. 372 (6545), pp. 984-989.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Biological Evolution*
Genome*
Adenosine Triphosphatases/*genetics
Adenosine Triphosphatases/*physiology
Chromosomes/*ultrastructure
DNA-Binding Proteins/*genetics
DNA-Binding Proteins/*physiology
Eukaryota/*genetics
Multiprotein Complexes/*genetics
Multiprotein Complexes/*physiology
Adenosine Triphosphatases/chemistry ; Algorithms ; Animals ; Cell Nucleolus/ultrastructure ; Cell Nucleus/ultrastructure ; Centromere/ultrastructure ; Chromosomes/chemistry ; Chromosomes, Human/chemistry ; Chromosomes, Human/ultrastructure ; DNA-Binding Proteins/chemistry ; Genome, Human ; Genomics ; Heterochromatin/ultrastructure ; Humans ; Interphase ; Mitosis ; Models, Biological ; Multiprotein Complexes/chemistry ; Telomere/ultrastructure
Czasopismo naukowe
Tytuł :
Crystal structure of SARS-CoV-2 Orf9b in complex with human TOM70 suggests unusual virus-host interactions.
Autorzy :
Gao X; NHC Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.; Sanming Project of Medicine in Shenzhen, National Clinical Research Center for Infectious Diseases, Shenzhen Third People's Hospital, Southern University of Science and Technology, Shenzhen, China.
Zhu K; NHC Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Qin B; NHC Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.; Sanming Project of Medicine in Shenzhen, National Clinical Research Center for Infectious Diseases, Shenzhen Third People's Hospital, Southern University of Science and Technology, Shenzhen, China.
Olieric V; Swiss Light Source Paul Scherrer Institut, Villigen, PSI, Switzerland.
Wang M; Swiss Light Source Paul Scherrer Institut, Villigen, PSI, Switzerland.
Cui S; NHC Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. .; Sanming Project of Medicine in Shenzhen, National Clinical Research Center for Infectious Diseases, Shenzhen Third People's Hospital, Southern University of Science and Technology, Shenzhen, China. .
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Źródło :
Nature communications [Nat Commun] 2021 May 14; Vol. 12 (1), pp. 2843. Date of Electronic Publication: 2021 May 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Coronavirus Nucleocapsid Proteins/*chemistry
Mitochondrial Membrane Transport Proteins/*chemistry
Multiprotein Complexes/*chemistry
Recombinant Proteins/*chemistry
Binding Sites/genetics ; COVID-19/virology ; Coronavirus Nucleocapsid Proteins/genetics ; Coronavirus Nucleocapsid Proteins/metabolism ; Cryoelectron Microscopy ; Crystallography, X-Ray ; Escherichia coli/genetics ; Host Microbial Interactions ; Humans ; Mitochondrial Membrane Transport Proteins/genetics ; Mitochondrial Membrane Transport Proteins/metabolism ; Models, Molecular ; Multiprotein Complexes/metabolism ; Multiprotein Complexes/ultrastructure ; Phosphoproteins/chemistry ; Phosphoproteins/genetics ; Phosphoproteins/metabolism ; Protein Binding ; Protein Domains ; Recombinant Proteins/metabolism ; SARS-CoV-2/genetics ; SARS-CoV-2/metabolism ; SARS-CoV-2/physiology
Czasopismo naukowe
Tytuł :
Cancer-associated mutations in the condensin II subunit CAPH2 cause genomic instability through telomere dysfunction and anaphase chromosome bridges.
Autorzy :
Weyburne E; Department of Molecular and Systems Biology, Dartmouth College, Hanover, New Hampshire, USA.
Bosco G; Department of Molecular and Systems Biology, Dartmouth College, Hanover, New Hampshire, USA.
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Źródło :
Journal of cellular physiology [J Cell Physiol] 2021 May; Vol. 236 (5), pp. 3579-3598. Date of Electronic Publication: 2020 Oct 20.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Anaphase*
Genomic Instability*
Adenosine Triphosphatases/*genetics
Cell Cycle Proteins/*metabolism
Chromosomes, Human/*metabolism
DNA-Binding Proteins/*genetics
Multiprotein Complexes/*genetics
Mutation/*genetics
Neoplasms/*genetics
Nuclear Proteins/*metabolism
Telomere/*pathology
Adenosine Triphosphatases/chemistry ; Adenosine Triphosphatases/metabolism ; Amino Acid Sequence ; Cell Cycle Proteins/chemistry ; Cell Cycle Proteins/genetics ; Chromatin/metabolism ; Chromosomal Proteins, Non-Histone/metabolism ; DNA Damage ; DNA-Binding Proteins/chemistry ; DNA-Binding Proteins/metabolism ; Humans ; Micronucleus, Germline/metabolism ; Multiprotein Complexes/chemistry ; Multiprotein Complexes/metabolism ; Mutant Proteins/metabolism ; Neoplasms/pathology ; Nuclear Proteins/chemistry ; Nuclear Proteins/genetics ; Protein Binding ; Protein Stability ; Protein Subunits/chemistry ; Protein Subunits/genetics ; Protein Subunits/metabolism ; S Phase ; Telomere/metabolism
Czasopismo naukowe
Tytuł :
MED12 interacts with the heat-shock transcription factor HSF1 and recruits CDK8 to promote the heat-shock response in mammalian cells.
Autorzy :
Srivastava P; Department of Biochemistry and Molecular Biology, Yamaguchi University School of Medicine, Ube, Japan.
Takii R; Department of Biochemistry and Molecular Biology, Yamaguchi University School of Medicine, Ube, Japan.
Okada M; Department of Biochemistry and Molecular Biology, Yamaguchi University School of Medicine, Ube, Japan.
Fujimoto M; Department of Biochemistry and Molecular Biology, Yamaguchi University School of Medicine, Ube, Japan.
Nakai A; Department of Biochemistry and Molecular Biology, Yamaguchi University School of Medicine, Ube, Japan.
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Źródło :
FEBS letters [FEBS Lett] 2021 Jul; Vol. 595 (14), pp. 1933-1948. Date of Electronic Publication: 2021 Jun 15.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cyclin-Dependent Kinase 8/*genetics
Heat Shock Transcription Factors/*genetics
Heat-Shock Response/*genetics
Mediator Complex/*genetics
Multiprotein Complexes/*genetics
Proteostasis/*genetics
Animals ; Cyclin-Dependent Kinase 8/metabolism ; Cyclin-Dependent Kinases/genetics ; Cyclin-Dependent Kinases/metabolism ; Fibroblasts ; Gene Expression Regulation ; HEK293 Cells ; HSP70 Heat-Shock Proteins/genetics ; HSP70 Heat-Shock Proteins/metabolism ; HeLa Cells ; Heat Shock Transcription Factors/metabolism ; Humans ; Mediator Complex/metabolism ; Mice ; Multiprotein Complexes/metabolism ; Neurons ; Osteoblasts ; Phosphorylation ; Protein Binding ; Signal Transduction ; Transcription, Genetic
Czasopismo naukowe
Tytuł :
Structural insight into BRCA1-BARD1 complex recruitment to damaged chromatin.
Autorzy :
Dai L; National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Dai Y; National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Han J; The MOE Key Laboratory of Biosystems Homeostasis & Protection, Zhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology and Innovation Center for Cell Signaling Network, Life Sciences Institute, Zhejiang University, Hangzhou, Zhejiang 310058, China.
Huang Y; National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Wang L; National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing 100049, China.
Huang J; The MOE Key Laboratory of Biosystems Homeostasis & Protection, Zhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology and Innovation Center for Cell Signaling Network, Life Sciences Institute, Zhejiang University, Hangzhou, Zhejiang 310058, China. Electronic address: .
Zhou Z; National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing 100049, China. Electronic address: .
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Źródło :
Molecular cell [Mol Cell] 2021 Jul 01; Vol. 81 (13), pp. 2765-2777.e6. Date of Electronic Publication: 2021 Jun 07.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
BRCA1 Protein/*chemistry
Histones/*chemistry
Multiprotein Complexes/*chemistry
Nucleosomes/*chemistry
Tumor Suppressor Proteins/*chemistry
Ubiquitin-Protein Ligases/*chemistry
Xenopus Proteins/*chemistry
Animals ; BRCA1 Protein/genetics ; Histones/genetics ; Humans ; Models, Molecular ; Multiprotein Complexes/genetics ; Mutation ; Nucleosomes/genetics ; Tumor Suppressor Proteins/genetics ; Ubiquitin-Protein Ligases/genetics ; Ubiquitination ; Xenopus Proteins/genetics ; Xenopus laevis
Czasopismo naukowe
Tytuł :
WNK1 is an assembly factor for the human ER membrane protein complex.
Autorzy :
Pleiner T; Division of Biology and Biological Engineering, California Institute of Technology, 1200 E. California Blvd., Pasadena, CA 91125, USA.
Hazu M; Division of Biology and Biological Engineering, California Institute of Technology, 1200 E. California Blvd., Pasadena, CA 91125, USA.
Tomaleri GP; Division of Biology and Biological Engineering, California Institute of Technology, 1200 E. California Blvd., Pasadena, CA 91125, USA.
Januszyk K; Division of Biology and Biological Engineering, California Institute of Technology, 1200 E. California Blvd., Pasadena, CA 91125, USA.
Oania RS; Division of Biology and Biological Engineering, California Institute of Technology, 1200 E. California Blvd., Pasadena, CA 91125, USA.
Sweredoski MJ; Division of Biology and Biological Engineering, California Institute of Technology, 1200 E. California Blvd., Pasadena, CA 91125, USA.
Moradian A; Division of Biology and Biological Engineering, California Institute of Technology, 1200 E. California Blvd., Pasadena, CA 91125, USA.
Guna A; Division of Biology and Biological Engineering, California Institute of Technology, 1200 E. California Blvd., Pasadena, CA 91125, USA.
Voorhees RM; Division of Biology and Biological Engineering, California Institute of Technology, 1200 E. California Blvd., Pasadena, CA 91125, USA. Electronic address: .
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Źródło :
Molecular cell [Mol Cell] 2021 Jul 01; Vol. 81 (13), pp. 2693-2704.e12. Date of Electronic Publication: 2021 May 07.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Endoplasmic Reticulum/*metabolism
Intracellular Membranes/*metabolism
Multiprotein Complexes/*metabolism
WNK Lysine-Deficient Protein Kinase 1/*metabolism
Endoplasmic Reticulum/genetics ; HeLa Cells ; Humans ; Multiprotein Complexes/genetics ; WNK Lysine-Deficient Protein Kinase 1/genetics
Czasopismo naukowe
Tytuł :
Dual mTORC1/mTORC2 Inhibition as a Host-Directed Therapeutic Target in Pathologically Distinct Mouse Models of Tuberculosis.
Autorzy :
Tasneen R; Johns Hopkins University, Baltimore, Maryland, USA.
Mortensen DS; Bristol Myers Squibb, San Diego, California, USA.
Converse PJ; Johns Hopkins University, Baltimore, Maryland, USA.
Urbanowski ME; Johns Hopkins University, Baltimore, Maryland, USA.
Upton A; TB Alliance, New York, New York, USA.
Fotouhi N; TB Alliance, New York, New York, USA.
Nuermberger E; Johns Hopkins University, Baltimore, Maryland, USA.
Hawryluk N; Bristol Myers Squibb, Global Health, San Diego, California, USA.
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Źródło :
Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2021 Jun 17; Vol. 65 (7), pp. e0025321. Date of Electronic Publication: 2021 Jun 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Multiprotein Complexes*
Tuberculosis*
Animals ; Mechanistic Target of Rapamycin Complex 1 ; Mechanistic Target of Rapamycin Complex 2 ; Mice ; Protein Kinase Inhibitors/pharmacology
Czasopismo naukowe
Tytuł :
Heterodimer Formation of the Homodimeric ABC Transporter OpuA.
Autorzy :
Alvarez-Sieiro P; Department of Biochemistry, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Nijenborgh 4, 9747 AG Groningen, The Netherlands.
Sikkema HR; Department of Biochemistry, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Nijenborgh 4, 9747 AG Groningen, The Netherlands.
Poolman B; Department of Biochemistry, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Nijenborgh 4, 9747 AG Groningen, The Netherlands.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 May 31; Vol. 22 (11). Date of Electronic Publication: 2021 May 31.
Typ publikacji :
Journal Article
MeSH Terms :
ATP-Binding Cassette Transporters/*genetics
Bacillus subtilis/*genetics
Bacterial Proteins/*genetics
Lipoproteins/*genetics
Multiprotein Complexes/*genetics
ATP-Binding Cassette Transporters/ultrastructure ; Adenosine Triphosphatases/genetics ; Amino Acid Sequence/genetics ; Bacterial Proteins/ultrastructure ; Dimerization ; Fluorescence Resonance Energy Transfer ; Lipoproteins/ultrastructure ; Multiprotein Complexes/ultrastructure ; Protein Multimerization/genetics ; Protein Subunits/genetics
Czasopismo naukowe
Tytuł :
The Exon Junction Complex and intron removal prevent re-splicing of mRNA.
Autorzy :
Joseph B; Developmental Biology Program, Sloan Kettering Institute, New York, New York, United States of America.; Louis V. Gerstner, Jr. Graduate School of Biomedical Sciences, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America.
Lai EC; Developmental Biology Program, Sloan Kettering Institute, New York, New York, United States of America.; Louis V. Gerstner, Jr. Graduate School of Biomedical Sciences, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America.
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Źródło :
PLoS genetics [PLoS Genet] 2021 May 25; Vol. 17 (5), pp. e1009563. Date of Electronic Publication: 2021 May 25 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Drosophila melanogaster*/genetics
Drosophila melanogaster*/metabolism
Exons*/genetics
Introns*/genetics
Multiprotein Complexes*
RNA Splicing*
RNA, Messenger/*metabolism
Alternative Splicing ; Animals ; RNA Splice Sites/genetics ; RNA, Messenger/genetics ; Transcriptome
Czasopismo naukowe
Tytuł :
The double-stranded DNA-binding proteins TEBP-1 and TEBP-2 form a telomeric complex with POT-1.
Autorzy :
Dietz S; Institute of Molecular Biology (IMB), Mainz, Germany.
Almeida MV; Institute of Molecular Biology (IMB), Mainz, Germany.; Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge, Cambridge, UK.; Department of Genetics, University of Cambridge, Cambridge, UK.
Nischwitz E; Institute of Molecular Biology (IMB), Mainz, Germany.
Schreier J; Institute of Molecular Biology (IMB), Mainz, Germany.
Viceconte N; Institute of Molecular Biology (IMB), Mainz, Germany.
Fradera-Sola A; Institute of Molecular Biology (IMB), Mainz, Germany.
Renz C; Institute of Molecular Biology (IMB), Mainz, Germany.
Ceron-Noriega A; Institute of Molecular Biology (IMB), Mainz, Germany.
Ulrich HD; Institute of Molecular Biology (IMB), Mainz, Germany.
Kappei D; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Ketting RF; Institute of Molecular Biology (IMB), Mainz, Germany.
Butter F; Institute of Molecular Biology (IMB), Mainz, Germany. .
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Źródło :
Nature communications [Nat Commun] 2021 May 11; Vol. 12 (1), pp. 2668. Date of Electronic Publication: 2021 May 11.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Caenorhabditis elegans Proteins/*metabolism
DNA/*metabolism
DNA-Binding Proteins/*metabolism
Multiprotein Complexes/*metabolism
Telomere/*metabolism
Telomere-Binding Proteins/*metabolism
Animals ; Animals, Genetically Modified ; Base Sequence ; Binding Sites/genetics ; Caenorhabditis elegans/genetics ; Caenorhabditis elegans/metabolism ; Caenorhabditis elegans Proteins/classification ; Caenorhabditis elegans Proteins/genetics ; DNA/genetics ; DNA-Binding Proteins/genetics ; Germ Cells/metabolism ; Microscopy, Fluorescence/methods ; Multiprotein Complexes/genetics ; Mutation ; Phylogeny ; Protein Binding ; Protein Isoforms/classification ; Protein Isoforms/genetics ; Protein Isoforms/metabolism ; Telomere/genetics ; Telomere-Binding Proteins/classification ; Telomere-Binding Proteins/genetics
Czasopismo naukowe
Tytuł :
Evidence for the Mycobacterial Mce4 Transporter Being a Multiprotein Complex.
Autorzy :
Rank L; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Herring LE; UNC Michael Hooker Proteomics Core Facility, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Braunstein M; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA .
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Źródło :
Journal of bacteriology [J Bacteriol] 2021 Apr 21; Vol. 203 (10). Date of Electronic Publication: 2021 Apr 21 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Cholesterol/*metabolism
Membrane Transport Proteins/*chemistry
Membrane Transport Proteins/*metabolism
Multiprotein Complexes/*chemistry
Multiprotein Complexes/*metabolism
Mycobacterium smegmatis/*metabolism
Adenosine Triphosphatases/metabolism ; Bacterial Proteins/chemistry ; Bacterial Proteins/genetics ; Bacterial Proteins/metabolism ; Biological Transport ; Membrane Transport Proteins/genetics ; Multiprotein Complexes/genetics ; Mycobacterium smegmatis/genetics ; Operon
Czasopismo naukowe
Tytuł :
Genetic analysis of the septal peptidoglycan synthase FtsWI complex supports a conserved activation mechanism for SEDS-bPBP complexes.
Autorzy :
Li Y; Department of Microbiology, Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan, HB, China.
Gong H; Department of Microbiology, Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan, HB, China.
Zhan R; Department of Microbiology, Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan, HB, China.
Ouyang S; Department of Microbiology, Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan, HB, China.
Park KT; Department of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City, KS, United States of America.
Lutkenhaus J; Department of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City, KS, United States of America.
Du S; Department of Microbiology, Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan, HB, China.
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Źródło :
PLoS genetics [PLoS Genet] 2021 Apr 15; Vol. 17 (4), pp. e1009366. Date of Electronic Publication: 2021 Apr 15 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Protein Conformation*
Bacterial Proteins/*ultrastructure
Escherichia coli Proteins/*ultrastructure
Membrane Proteins/*ultrastructure
Multiprotein Complexes/*ultrastructure
Penicillin-Binding Proteins/*ultrastructure
Peptidoglycan Glycosyltransferase/*ultrastructure
Bacterial Proteins/chemistry ; Bacterial Proteins/genetics ; Escherichia coli Proteins/chemistry ; Escherichia coli Proteins/genetics ; Membrane Proteins/chemistry ; Membrane Proteins/genetics ; Models, Molecular ; Multiprotein Complexes/chemistry ; Multiprotein Complexes/genetics ; Penicillin-Binding Proteins/chemistry ; Penicillin-Binding Proteins/genetics ; Peptidoglycan/chemistry ; Peptidoglycan/genetics ; Peptidoglycan/ultrastructure ; Peptidoglycan Glycosyltransferase/chemistry ; Peptidoglycan Glycosyltransferase/genetics ; Peptidyl Transferases/chemistry ; Peptidyl Transferases/genetics ; Peptidyl Transferases/ultrastructure
Czasopismo naukowe
Tytuł :
Structure of the catalytic core of the Integrator complex.
Autorzy :
Pfleiderer MM; European Molecular Biology Laboratory, 71 Avenue des Martyrs, 38042 Grenoble, France.
Galej WP; European Molecular Biology Laboratory, 71 Avenue des Martyrs, 38042 Grenoble, France. Electronic address: .
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Źródło :
Molecular cell [Mol Cell] 2021 Mar 18; Vol. 81 (6), pp. 1246-1259.e8. Date of Electronic Publication: 2021 Feb 05.
Typ publikacji :
Journal Article
MeSH Terms :
Multiprotein Complexes*/chemistry
Multiprotein Complexes*/genetics
Multiprotein Complexes*/metabolism
Multiprotein Complexes*/ultrastructure
Transcription Termination, Genetic*
Carrier Proteins/chemistry ; Carrier Proteins/genetics ; Carrier Proteins/metabolism ; Cell Cycle Proteins/chemistry ; Cell Cycle Proteins/genetics ; Cell Cycle Proteins/metabolism ; Cryoelectron Microscopy ; HEK293 Cells ; Humans ; Intracellular Signaling Peptides and Proteins/chemistry ; Intracellular Signaling Peptides and Proteins/genetics ; Intracellular Signaling Peptides and Proteins/metabolism ; Protein Subunits/chemistry ; Protein Subunits/genetics ; Protein Subunits/metabolism
Czasopismo naukowe
Tytuł :
Structure of intact human MCU supercomplex with the auxiliary MICU subunits.
Autorzy :
Zhuo W; Ministry of Education Key Laboratory of Protein Science, Tsinghua-Peking Joint Center for Life Sciences, Beijing Advanced Innovation Center for Structural Biology, School of Life Sciences, Tsinghua University, Beijing, 100084, China. .
Zhou H; Ministry of Education Key Laboratory of Protein Science, Tsinghua-Peking Joint Center for Life Sciences, Beijing Advanced Innovation Center for Structural Biology, School of Life Sciences, Tsinghua University, Beijing, 100084, China.
Guo R; Ministry of Education Key Laboratory of Protein Science, Tsinghua-Peking Joint Center for Life Sciences, Beijing Advanced Innovation Center for Structural Biology, School of Life Sciences, Tsinghua University, Beijing, 100084, China.
Yi J; Ministry of Education Key Laboratory of Protein Science, Tsinghua-Peking Joint Center for Life Sciences, Beijing Advanced Innovation Center for Structural Biology, School of Life Sciences, Tsinghua University, Beijing, 100084, China.
Zhang L; Ministry of Education Key Laboratory of Protein Science, Tsinghua-Peking Joint Center for Life Sciences, Beijing Advanced Innovation Center for Structural Biology, School of Life Sciences, Tsinghua University, Beijing, 100084, China.
Yu L; Ministry of Education Key Laboratory of Protein Science, Tsinghua-Peking Joint Center for Life Sciences, Beijing Advanced Innovation Center for Structural Biology, School of Life Sciences, Tsinghua University, Beijing, 100084, China.
Sui Y; Ministry of Education Key Laboratory of Protein Science, Tsinghua-Peking Joint Center for Life Sciences, Beijing Advanced Innovation Center for Structural Biology, School of Life Sciences, Tsinghua University, Beijing, 100084, China.
Zeng W; Institute for Immunology and School of Medicine, Tsinghua-Peking Center for Life Sciences, Tsinghua University, Beijing, 100084, China.; Beijing Key Laboratory for Immunological Research on Chronic Diseases, Tsinghua University, Beijing, 100084, China.
Wang P; Cryo-EM Facility Center, Southern University of Science & Technology, Shenzhen, 518055, China. .
Yang M; Ministry of Education Key Laboratory of Protein Science, Tsinghua-Peking Joint Center for Life Sciences, Beijing Advanced Innovation Center for Structural Biology, School of Life Sciences, Tsinghua University, Beijing, 100084, China. .
Pokaż więcej
Źródło :
Protein & cell [Protein Cell] 2021 Mar; Vol. 12 (3), pp. 220-229.
Typ publikacji :
Letter; Research Support, Non-U.S. Gov't
MeSH Terms :
Calcium Channels/*metabolism
Mitochondrial Proteins/*metabolism
Multiprotein Complexes/*metabolism
Calcium Channels/chemistry ; Calcium Channels/genetics ; HEK293 Cells ; Humans ; Mitochondrial Proteins/chemistry ; Mitochondrial Proteins/genetics ; Multiprotein Complexes/chemistry ; Multiprotein Complexes/genetics
Raport

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