Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Przeglądasz jako GOŚĆ

Wyszukujesz frazę ""Muscarinic Antagonists"" wg kryterium: Temat


Tytuł :
The impact of long-acting muscarinic antagonists on mucus hypersecretion and cough in chronic obstructive pulmonary disease: a systematic review.
Autorzy :
Calzetta L; Dept of Medicine and Surgery, Respiratory Disease and Lung Function Unit, University of Parma, Parma, Italy .
Ritondo BL; Unit of Respiratory Medicine, Dept of Experimental Medicine, University of Rome 'Tor Vergata', Rome, Italy.
Zappa MC; Pulmonology Dept, Sandro Pertini Hospital, Rome, Italy.
Manzetti GM; Unit of Respiratory Medicine, Dept of Experimental Medicine, University of Rome 'Tor Vergata', Rome, Italy.
Perduno A; Unit of Respiratory Medicine, Dept of Experimental Medicine, University of Rome 'Tor Vergata', Rome, Italy.
Shute J; School of Pharmacy and Biomedical Science, University of Portsmouth, Portsmouth, UK.
Rogliani P; Unit of Respiratory Medicine, Dept of Experimental Medicine, University of Rome 'Tor Vergata', Rome, Italy.
Pokaż więcej
Źródło :
European respiratory review : an official journal of the European Respiratory Society [Eur Respir Rev] 2022 May 04; Vol. 31 (164). Date of Electronic Publication: 2022 May 04 (Print Publication: 2022).
Typ publikacji :
Journal Article; Review; Systematic Review
MeSH Terms :
Muscarinic Antagonists*/adverse effects
Pulmonary Disease, Chronic Obstructive*/diagnosis
Pulmonary Disease, Chronic Obstructive*/drug therapy
Cough/diagnosis ; Cough/drug therapy ; Humans ; Mucus ; Tiotropium Bromide
Czasopismo naukowe
Tytuł :
Implications of Antimuscarinic Autoantibodies in Postural Tachycardia Syndrome.
Autorzy :
Li H; Department of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
Zhang G; Department of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
Forsythe E; Department of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
Okamoto LE; Autonomic Dysfunction Center, Division of Clinical Pharmacology, Vanderbilt University Medical Center, Nashville, TN, USA.
Yu X; Department of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA. .
Pokaż więcej
Źródło :
Journal of cardiovascular translational research [J Cardiovasc Transl Res] 2022 Apr; Vol. 15 (2), pp. 438-440. Date of Electronic Publication: 2021 Aug 18.
Typ publikacji :
Journal Article
MeSH Terms :
Muscarinic Antagonists*/pharmacology
Postural Orthostatic Tachycardia Syndrome*/diagnosis
Autoantibodies ; Heart Rate ; Humans ; Receptor, Muscarinic M2
Czasopismo naukowe
Tytuł :
Patient Experience of Antimuscarinic Treatment for Overactive Bladder: A Qualitative Exploration of Online Forum Content.
Autorzy :
Morocco E; From the Department of Obstetrics and Gynecology, University of Southern California, Los Angeles, CA.
Latack K; Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, MI.
Ciesielski K; From the Department of Obstetrics and Gynecology, University of Southern California, Los Angeles, CA.
Nguyen B; From the Department of Obstetrics and Gynecology, University of Southern California, Los Angeles, CA.
Dancz C; From the Department of Obstetrics and Gynecology, University of Southern California, Los Angeles, CA.
Pokaż więcej
Źródło :
Female pelvic medicine & reconstructive surgery [Female Pelvic Med Reconstr Surg] 2022 Mar 01; Vol. 28 (3), pp. e49-e54.
Typ publikacji :
Journal Article
MeSH Terms :
Muscarinic Antagonists*/adverse effects
Urinary Bladder, Overactive*/drug therapy
Female ; Humans ; Male ; Patient Outcome Assessment ; Solifenacin Succinate/adverse effects ; Tolterodine Tartrate
Czasopismo naukowe
Tytuł :
The antimuscarinic agent biperiden selectively impairs recognition of abstract figures without affecting the processing of non-words.
Autorzy :
Toth M; Department of Neuropsychology and Psychopharmacology, Faculty of Psychology and Neuroscience, Maastricht University, The Netherlands.
Sambeth A; Department of Neuropsychology and Psychopharmacology, Faculty of Psychology and Neuroscience, Maastricht University, The Netherlands.
Blokland A; Department of Neuropsychology and Psychopharmacology, Faculty of Psychology and Neuroscience, Maastricht University, The Netherlands.
Pokaż więcej
Źródło :
Human psychopharmacology [Hum Psychopharmacol] 2022 Mar; Vol. 37 (2), pp. e2819. Date of Electronic Publication: 2021 Sep 17.
Typ publikacji :
Journal Article; Randomized Controlled Trial
MeSH Terms :
Biperiden*
Muscarinic Antagonists*
Cross-Over Studies ; Humans ; Memory Disorders/drug therapy ; Reaction Time
Czasopismo naukowe
Tytuł :
Biomarkers to Predict Response to Inhaled Corticosteroids and Long-Acting Muscarinic Antagonists in Adolescents and Adults with Mild Persistent Asthma.
Autorzy :
Krishnan JA; University of Illinois at Chicago, Chicago, Illinois.
Lazarus SC; University of California, San Francisco, California.
Blake KV; Nemours Children's Health, Jacksonville, Florida.
Sorkness CA; University of Wisconsin, Madison, Wisconsin.
Covar R; National Jewish Health, Denver, Colorado.
Dyer AM; Pennsylvania State University, Hershey, Pennsylvania.
Lang JE; Duke University School of Medicine, Durham, North Carolina.
Lugogo NL; University of Michigan, Ann Arbor, Michigan.
Mauger DT; Pennsylvania State University, Hershey, Pennsylvania.
Wechsler ME; National Jewish Health, Denver, Colorado.
Wenzel SE; University of Pittsburgh, Pittsburgh, Pennsylvania.
Cardet JC; University of South Florida, Tampa, Florida.
Castro M; University of Kansas School of Medicine, Kansas City, Kansas.
Israel E; Harvard Medical School Brigham & Women's Hospital, Boston, Massachusetts; and.
Phipatanakul W; Boston Children's Hospital, Boston, Massachusetts.
King TS; Pennsylvania State University, Hershey, Pennsylvania.
Pokaż więcej
Źródło :
Annals of the American Thoracic Society [Ann Am Thorac Soc] 2022 Mar; Vol. 19 (3), pp. 372-380.
Typ publikacji :
Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural
MeSH Terms :
Asthma*/drug therapy
Muscarinic Antagonists*/therapeutic use
Administration, Inhalation ; Adolescent ; Adrenal Cortex Hormones/therapeutic use ; Adult ; Biomarkers ; Humans ; Infant ; Prospective Studies
Czasopismo naukowe
Tytuł :
Lung deposition of inhaled once-daily long-acting muscarinic antagonists via standard jet nebulizer or dry powder inhaler, measured using functional respiratory imaging, in patients with chronic obstructive pulmonary disease.
Autorzy :
Crater GD; Theravance Biopharma US, Inc., South San Francisco, CA, USA (former)Clinical Pharma Specialist Consultants, LLC, Raleigh, NC, USA (current).
Johnson K; Theravance Biopharma US, Inc., 901 Gateway Boulevard, South San Francisco, CA 94080, USA.
Ward J; Mylan Pharma UK Ltd., Sandwich, UK.
Backer J; FLUIDDA, Kontich, Belgium.
Pokaż więcej
Źródło :
Therapeutic advances in respiratory disease [Ther Adv Respir Dis] 2022 Jan-Dec; Vol. 16, pp. 17534666221077561.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Muscarinic Antagonists*
Pulmonary Disease, Chronic Obstructive*/diagnosis
Pulmonary Disease, Chronic Obstructive*/drug therapy
Administration, Inhalation ; Aged ; Bronchodilator Agents ; Dry Powder Inhalers ; Forced Expiratory Volume ; Humans ; Lung ; Male ; Middle Aged ; Nebulizers and Vaporizers ; Powders/pharmacology ; Powders/therapeutic use ; Tiotropium Bromide/therapeutic use
Czasopismo naukowe
Tytuł :
Physostigmine should be used more readily for antimuscarinic toxicity: PRO.
Autorzy :
Dawson A; NSW Poisons Information Centre, Westmead Childrens Hospital, Sydney, Australia.; Central Clinical School, Royal Prince Alfred Hospital, University of Sydney, Sydney, Australia.
Pokaż więcej
Źródło :
British journal of clinical pharmacology [Br J Clin Pharmacol] 2022 Jan; Vol. 88 (1), pp. 58-60. Date of Electronic Publication: 2021 Nov 16.
Typ publikacji :
Journal Article
MeSH Terms :
Muscarinic Antagonists*/adverse effects
Physostigmine*/adverse effects
Cholinesterase Inhibitors/toxicity ; Humans
Czasopismo naukowe
Tytuł :
Quantitative analysis of efficacy and safety of LABA/LAMA fixed-dose combinations in the treatment of stable COPD.
Autorzy :
Gong Y; Center for Drug Clinical Evaluation, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Lv Y; Center for Drug Clinical Evaluation, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Liu H; Center for Drug Clinical Evaluation, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Zheng Q; Center for Drug Clinical Evaluation, Shanghai University of Traditional Chinese Medicine, No. 1200 Cailun Road, Shanghai 201203, China.
Li L; Center for Drug Clinical Evaluation, Shanghai University of Traditional Chinese Medicine, No. 1200 Cailun Road, Shanghai 201203, China.
Pokaż więcej
Źródło :
Therapeutic advances in respiratory disease [Ther Adv Respir Dis] 2022 Jan-Dec; Vol. 16, pp. 17534666211066068.
Typ publikacji :
Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't
MeSH Terms :
Muscarinic Antagonists*
Pulmonary Disease, Chronic Obstructive*/diagnosis
Pulmonary Disease, Chronic Obstructive*/drug therapy
Adrenergic beta-2 Receptor Agonists ; Bronchodilator Agents ; Drug Combinations ; Forced Expiratory Volume ; Formoterol Fumarate ; Glycopyrrolate ; Humans ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Triple versus LAMA/LABA combination therapy for Japanese patients with COPD: A systematic review and meta-analysis.
Autorzy :
Koarai A; Department of Respiratory Medicine, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai, 980-8574, Japan. Electronic address: .
Yamada M; Department of Respiratory Medicine, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai, 980-8574, Japan. Electronic address: .
Ichikawa T; Department of Respiratory Medicine, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai, 980-8574, Japan. Electronic address: .
Fujino N; Department of Respiratory Medicine, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai, 980-8574, Japan. Electronic address: .
Kawayama T; Division of Respirology, Neurology and Rheumatology, Department of Medicine, Kurume University School of Medicine, 67 Asahi-machi, Kurume, 830-0011, Japan. Electronic address: .
Sugiura H; Department of Respiratory Medicine, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai, 980-8574, Japan. Electronic address: .
Pokaż więcej
Źródło :
Respiratory investigation [Respir Investig] 2022 Jan; Vol. 60 (1), pp. 90-98. Date of Electronic Publication: 2021 Jun 06.
Typ publikacji :
Journal Article; Meta-Analysis; Systematic Review
MeSH Terms :
Muscarinic Antagonists*/therapeutic use
Pulmonary Disease, Chronic Obstructive*/drug therapy
Pulmonary Disease, Chronic Obstructive*/epidemiology
Administration, Inhalation ; Adrenal Cortex Hormones/therapeutic use ; Adrenergic beta-2 Receptor Agonists/therapeutic use ; Bronchodilator Agents/therapeutic use ; Drug Therapy, Combination ; Humans ; Japan/epidemiology ; Muscarinic Agonists/therapeutic use ; Quality of Life
Czasopismo naukowe
Tytuł :
Physostigmine should be used more readily for antimuscarinic toxicity: CON.
Autorzy :
Mullins ME; Division of Medical Toxicology, Department of Emergency Medicine, Washington University School of Medicine, Saint Louis, Missouri, USA.
Pokaż więcej
Źródło :
British journal of clinical pharmacology [Br J Clin Pharmacol] 2022 Jan; Vol. 88 (1), pp. 61-63. Date of Electronic Publication: 2021 Nov 16.
Typ publikacji :
Journal Article
MeSH Terms :
Muscarinic Antagonists*/adverse effects
Physostigmine*/adverse effects
Cholinesterase Inhibitors/toxicity ; Humans
Czasopismo naukowe
Tytuł :
Impact of Bladder Wall Thickness on the Outcomes of Antimuscarinic Treatment in Women with Overactive Bladder.
Autorzy :
Azab SS; Urology Department, Faculty of Medicine, October 6 University, Cairo, Egypt.
El Sayed O; Urology Department, Faculty of Medicine, October 6 University, Cairo, Egypt.
El Kafoury M; Clinical Pathology Department, National Research Center, Cairo, Egypt.
Pokaż więcej
Źródło :
Urologia internationalis [Urol Int] 2022; Vol. 106 (3), pp. 291-297. Date of Electronic Publication: 2021 Dec 16.
Typ publikacji :
Journal Article
MeSH Terms :
Muscarinic Antagonists*/therapeutic use
Urinary Bladder, Overactive*/diagnosis
Female ; Humans ; Solifenacin Succinate/therapeutic use ; Urinary Bladder ; Urodynamics/physiology
Czasopismo naukowe
Tytuł :
Once daily long-acting beta 2-agonists and long-acting muscarinic antagonists in a combined inhaler versus placebo for chronic obstructive pulmonary disease.
Autorzy :
Ibrahim AS; Intensive Care Unit, Aminu Kano Teaching Hospital, Kano, Nigeria.
Pokaż więcej
Źródło :
International journal of nursing practice [Int J Nurs Pract] 2021 Dec; Vol. 27 (6), pp. e12982. Date of Electronic Publication: 2021 Jun 02.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Muscarinic Antagonists*/adverse effects
Pulmonary Disease, Chronic Obstructive*/drug therapy
Humans ; Nebulizers and Vaporizers
Czasopismo naukowe
Tytuł :
Efficacy and cardiovascular safety of LAMA in patients with COPD: a systematic review and meta-analysis.
Autorzy :
Zhang C; Department of Intensive Care Unit, Lanzhou University First Affiliated Hospital, Lanzhou, Gansu, China.; The First Clinical Medical College of Lanzhou University, Lanzhou University, Lanzhou, Gansu, China.
Zhang M; Department of Intensive Care Unit, Lanzhou University First Affiliated Hospital, Lanzhou, Gansu, China.; The First Clinical Medical College of Lanzhou University, Lanzhou University, Lanzhou, Gansu, China.
Wang Y; Department of Intensive Care Unit, Lanzhou University First Affiliated Hospital, Lanzhou, Gansu, China.; The First Clinical Medical College of Lanzhou University, Lanzhou University, Lanzhou, Gansu, China.
Xiong H; Department of Intensive Care Unit, Lanzhou University First Affiliated Hospital, Lanzhou, Gansu, China.; The First Clinical Medical College of Lanzhou University, Lanzhou University, Lanzhou, Gansu, China.
Huang Q; Department of Intensive Care Unit, Lanzhou University First Affiliated Hospital, Lanzhou, Gansu, China.; The First Clinical Medical College of Lanzhou University, Lanzhou University, Lanzhou, Gansu, China.
Shuai T; Department of Intensive Care Unit, Lanzhou University First Affiliated Hospital, Lanzhou, Gansu, China.; The First Clinical Medical College of Lanzhou University, Lanzhou University, Lanzhou, Gansu, China.
Liu J; Department of Intensive Care Unit, Lanzhou University First Affiliated Hospital, Lanzhou, Gansu, China .
Pokaż więcej
Źródło :
Journal of investigative medicine : the official publication of the American Federation for Clinical Research [J Investig Med] 2021 Dec; Vol. 69 (8), pp. 1391-1398. Date of Electronic Publication: 2021 Aug 06.
Typ publikacji :
Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't; Systematic Review
MeSH Terms :
Muscarinic Antagonists*/adverse effects
Pulmonary Disease, Chronic Obstructive*/complications
Pulmonary Disease, Chronic Obstructive*/drug therapy
Adrenergic beta-2 Receptor Agonists ; Dyspnea ; Humans ; Lung
Czasopismo naukowe
Tytuł :
Pooled analysis of the efficacy and safety of tibial nerve stimulation versus antimuscarinic agents in the management of overactive bladder syndrome.
Autorzy :
Xia L; Department of Neurology, Weifang Traditional Chinese Medicine Hospital, China.
Yan H; Department of Urology, Liaocheng People's Hospital, China.
Sun Y; Department of Ultrasound, Weifang People's Hospital, China.
Zhu Y; Department of Urology, Weifang People's Hospital, China.
Wu Y; Department of Urology, Weifang People's Hospital, China.
Chen Z; Department of Urology, Weifang People's Hospital, China.
Su S; Department of Urology, Weifang People's Hospital, China.
Pokaż więcej
Źródło :
Medicine [Medicine (Baltimore)] 2021 Nov 12; Vol. 100 (45), pp. e27745.
Typ publikacji :
Journal Article; Meta-Analysis; Systematic Review
MeSH Terms :
Muscarinic Antagonists*/therapeutic use
Urinary Bladder, Overactive*/drug therapy
Humans ; Tibial Nerve
Czasopismo naukowe
Tytuł :
Biperiden Challenge Model in Healthy Elderly as Proof-of-Pharmacology Tool: A Randomized, Placebo-Controlled Trial.
Autorzy :
Bakker C; Centre for Human Drug Research, Leiden, The Netherlands.; Leiden University Medical Centre, Leiden, The Netherlands.
van Esdonk MJ; Centre for Human Drug Research, Leiden, The Netherlands.
Stuurman RFE; Centre for Human Drug Research, Leiden, The Netherlands.
Borghans LGJM; Centre for Human Drug Research, Leiden, The Netherlands.
de Kam ML; Centre for Human Drug Research, Leiden, The Netherlands.
van Gerven JMA; Centre for Human Drug Research, Leiden, The Netherlands.
Groeneveld GJ; Centre for Human Drug Research, Leiden, The Netherlands.; Leiden University Medical Centre, Leiden, The Netherlands.
Pokaż więcej
Źródło :
Journal of clinical pharmacology [J Clin Pharmacol] 2021 Nov; Vol. 61 (11), pp. 1466-1478. Date of Electronic Publication: 2021 Jul 29.
Typ publikacji :
Journal Article; Randomized Controlled Trial
MeSH Terms :
Biperiden/*pharmacology
Muscarinic Antagonists/*pharmacology
Aged ; Attention/drug effects ; Biperiden/pharmacokinetics ; Cognition/drug effects ; Cross-Over Studies ; Dose-Response Relationship, Drug ; Double-Blind Method ; Female ; Healthy Volunteers ; Humans ; Male ; Muscarinic Antagonists/pharmacokinetics ; Reaction Time/drug effects
Czasopismo naukowe
Tytuł :
Impact of long-acting muscarinic antagonists on small airways in asthma and COPD: A systematic review.
Autorzy :
Rogliani P; Unit of Respiratory Medicine, Department of Experimental Medicine, University of Rome 'Tor Vergata', Rome, Italy. Electronic address: .
Ritondo BL; Unit of Respiratory Medicine, Department of Experimental Medicine, University of Rome 'Tor Vergata', Rome, Italy.
Puxeddu E; Unit of Respiratory Medicine, Department of Experimental Medicine, University of Rome 'Tor Vergata', Rome, Italy.
Cazzola M; Unit of Respiratory Medicine, Department of Experimental Medicine, University of Rome 'Tor Vergata', Rome, Italy.
Calzetta L; Department of Medicine and Surgery, Respiratory Disease and Lung Function Unit, University of Parma, Parma, Italy.
Pokaż więcej
Źródło :
Respiratory medicine [Respir Med] 2021 Nov-Dec; Vol. 189, pp. 106639. Date of Electronic Publication: 2021 Oct 05.
Typ publikacji :
Journal Article; Systematic Review
MeSH Terms :
Asthma/*drug therapy
Muscarinic Antagonists/*therapeutic use
Pulmonary Disease, Chronic Obstructive/*drug therapy
Administration, Inhalation ; Asthma/pathology ; Humans ; Muscarinic Antagonists/administration & dosage ; Pulmonary Disease, Chronic Obstructive/pathology
Czasopismo naukowe
Tytuł :
Stable Atropine Loaded Film As a Potential Ocular Delivery System For Treatment Of Myopia.
Autorzy :
Ji M; Department of Pharmaceutics, School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, 110016, Liaoning, China.
Liu H; Department of Pharmaceutics, School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, 110016, Liaoning, China.
Ma S; Department of Pharmaceutics, School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, 110016, Liaoning, China.
Kong J; Department of Ophthalmology, the Fourth Affiliated Hospital of China Medical University, Shenyang, 110016, Liaoning, China.
Jia Y; Affiliated Hospital of Inner Mongolia University for the Nationalities, Tongliao, 028000, Neimenggu, China.
Gou J; Department of Pharmaceutics, School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, 110016, Liaoning, China.
Yin T; School of Functional Food and Wine, Shenyang Pharmaceutical University, Shenyang, 110016, Liaoning, China.
He H; Department of Pharmaceutics, School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, 110016, Liaoning, China.
Zhang Y; Department of Pharmaceutics, School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, 110016, Liaoning, China. .
Tang X; Department of Pharmaceutics, School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, 110016, Liaoning, China.
Pokaż więcej
Źródło :
Pharmaceutical research [Pharm Res] 2021 Nov; Vol. 38 (11), pp. 1931-1946. Date of Electronic Publication: 2021 Nov 12.
Typ publikacji :
Journal Article
MeSH Terms :
Atropine/*administration & dosage
Drug Delivery Systems/*methods
Muscarinic Antagonists/*administration & dosage
Myopia/*drug therapy
Administration, Ophthalmic ; Animals ; Atropine/pharmacokinetics ; Biological Availability ; Disease Models, Animal ; Drug Evaluation, Preclinical ; Guinea Pigs ; Humans ; Male ; Muscarinic Antagonists/pharmacokinetics ; Myopia/diagnosis ; Rabbits ; Spectroscopy, Fourier Transform Infrared
Czasopismo naukowe
Tytuł :
3-Quinuclidinyl benzilate (agent BZ) toxicokinetics in rats.
Autorzy :
Dlabkova A; Department of Toxicology and Military Pharmacy, Faculty of Military Health Sciences in Hradec Kralove, University of Defence, Brno, Czech Republic.
Herman D; Department of Toxicology and Military Pharmacy, Faculty of Military Health Sciences in Hradec Kralove, University of Defence, Brno, Czech Republic.
Cechova L; Department of Toxicology and Military Pharmacy, Faculty of Military Health Sciences in Hradec Kralove, University of Defence, Brno, Czech Republic.; Department of Pharmaceutical Chemistry and Pharmaceutical Analysis, Faculty of Pharmacy, Charles University, Prague, Czech Republic.
Hroch M; Department of Medical Biochemistry, Faculty of Medicine in Hradec Kralove, Charles University, Prague, Czech Republic.
Vanova N; Department of Pharmaceutical Chemistry and Pharmaceutical Analysis, Faculty of Pharmacy, Charles University, Prague, Czech Republic.
Zdarova Karasova J; Department of Toxicology and Military Pharmacy, Faculty of Military Health Sciences in Hradec Kralove, University of Defence, Brno, Czech Republic.
Pokaż więcej
Źródło :
Basic & clinical pharmacology & toxicology [Basic Clin Pharmacol Toxicol] 2021 Sep; Vol. 129 (3), pp. 246-255. Date of Electronic Publication: 2021 Jun 30.
Typ publikacji :
Journal Article
MeSH Terms :
Muscarinic Antagonists/*metabolism
Muscarinic Antagonists/*toxicity
Quinuclidinyl Benzilate/*metabolism
Quinuclidinyl Benzilate/*toxicity
Animals ; Bile/metabolism ; Brain/metabolism ; Male ; Metabolome ; Muscarinic Antagonists/blood ; Muscarinic Antagonists/urine ; Quinuclidinyl Benzilate/blood ; Quinuclidinyl Benzilate/urine ; Rats ; Rats, Wistar ; Toxicokinetics ; Urine
Czasopismo naukowe
Tytuł :
Scopolamine prevents aberrant mossy fiber sprouting and facilitates remission of epilepsy after brain injury.
Autorzy :
Meller S; Department of Pharmacology, Toxicology, and Pharmacy, University of Veterinary Medicine, Hannover, Germany.
Käufer C; Department of Pharmacology, Toxicology, and Pharmacy, University of Veterinary Medicine, Hannover, Germany.
Gailus B; Department of Pharmacology, Toxicology, and Pharmacy, University of Veterinary Medicine, Hannover, Germany; Center for Systems Neuroscience, Hannover, Germany.
Brandt C; Department of Pharmacology, Toxicology, and Pharmacy, University of Veterinary Medicine, Hannover, Germany.
Löscher W; Department of Pharmacology, Toxicology, and Pharmacy, University of Veterinary Medicine, Hannover, Germany; Center for Systems Neuroscience, Hannover, Germany. Electronic address: .
Pokaż więcej
Źródło :
Neurobiology of disease [Neurobiol Dis] 2021 Oct; Vol. 158, pp. 105446. Date of Electronic Publication: 2021 Jul 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Brain Injuries, Traumatic/*complications
Epilepsy, Temporal Lobe/*prevention & control
Mossy Fibers, Hippocampal/*drug effects
Muscarinic Antagonists/*pharmacology
Scopolamine/*pharmacology
Animals ; Behavior, Animal/drug effects ; Cognition/drug effects ; Computer Simulation ; Electroencephalography ; Epilepsy, Temporal Lobe/chemically induced ; Epilepsy, Temporal Lobe/etiology ; Female ; Glial Fibrillary Acidic Protein/metabolism ; Lithium ; Muscarinic Antagonists/pharmacokinetics ; Muscarinic Antagonists/therapeutic use ; Rats ; Rats, Sprague-Dawley ; Scopolamine/pharmacokinetics ; Scopolamine/therapeutic use ; Seizures/prevention & control
Czasopismo naukowe
Tytuł :
Efficacy of umeclidinium/vilanterol according to the degree of reversibility of airflow limitation at screening: a post hoc analysis of the EMAX trial.
Autorzy :
Vogelmeier CF; Department of Medicine, Pulmonary and Critical Care Medicine, University Medical Centre Giessen and Marburg, Philipps-Universität Marburg, German Centre for Lung Research (DZL), Baldingerstraße, 35043, Marburg, Germany. .
Jones PW; GSK, Brentford, Middlesex, UK.
Kerwin EM; Altitude Clinical Consulting and Clinical Research Institute of Southern Oregon, Medford, OR, USA.
Boucot IH; GSK, Brentford, Middlesex, UK.
Maltais F; Centre de Pneumologie, Institut Universitaire de Cardiologie et de Pneumologie de Québec, Université Laval, Québec, Québec, Canada.
Tombs L; Precise Approach Ltd, GSK, Brentford, Middlesex, UK.
Compton C; GSK, Brentford, Middlesex, UK.
Lipson DA; Respiratory Clinical Sciences, GSK, Collegeville, PA, USA.; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Bjermer LH; Respiratory Medicine and Allergology, Lund University, Lund, Sweden.
Pokaż więcej
Źródło :
Respiratory research [Respir Res] 2021 Oct 28; Vol. 22 (1), pp. 279. Date of Electronic Publication: 2021 Oct 28.
Typ publikacji :
Journal Article; Multicenter Study; Randomized Controlled Trial
MeSH Terms :
Adrenergic beta-2 Receptor Agonists/*administration & dosage
Benzyl Alcohols/*administration & dosage
Bronchodilator Agents/*administration & dosage
Chlorobenzenes/*administration & dosage
Lung/*drug effects
Muscarinic Antagonists/*administration & dosage
Pulmonary Disease, Chronic Obstructive/*drug therapy
Quinuclidines/*administration & dosage
Adrenergic beta-2 Receptor Agonists/adverse effects ; Aged ; Benzyl Alcohols/adverse effects ; Bronchodilator Agents/adverse effects ; Chlorobenzenes/adverse effects ; Double-Blind Method ; Drug Combinations ; Female ; Forced Expiratory Volume ; Humans ; Lung/physiopathology ; Male ; Middle Aged ; Muscarinic Antagonists/adverse effects ; Pulmonary Disease, Chronic Obstructive/diagnosis ; Pulmonary Disease, Chronic Obstructive/physiopathology ; Quinuclidines/adverse effects ; Recovery of Function ; Time Factors ; Treatment Outcome
Czasopismo naukowe

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies