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    Tytuł:
    A randomized trial to determine the impact of indacaterol/glycopyrronium on nighttime oxygenation and symptoms in patients with moderate-to-severe COPD: the DuoSleep study
    Autorzy:
    Lehmann, Sverre
    Ringbæk, Thomas
    Løkke, Anders
    Grote, Ludger
    Hedner, Jan
    Lindberg, Eva
    Pokaż więcej
    Temat:
    Original Research
    bronchodilator
    sleep
    hypoxia
    quality of life
    lung function
    Respiratory Medicine and Allergy
    Lungmedicin och allergi
    OBSTRUCTIVE PULMONARY-DISEASE
    SALMETEROL-FLUTICASONE
    DOUBLE-BLIND
    STANDARDIZATION
    GLYCOPYRRONIUM
    DESATURATION
    THERAPY
    Public Health, Environmental and Occupational Health
    Health Policy
    Pulmonary and Respiratory Medicine
    General Medicine
    FEV1/FVC ratio
    Sleep disorder
    medicine.disease
    medicine
    Indacaterol
    medicine.drug
    business.industry
    business
    Crossover study
    Placebo
    COPD
    Asthma
    Anesthesia
    Somnolence
    medicine.symptom
    lcsh:Diseases of the respiratory system
    lcsh:RC705-779
    Adrenergic beta-2 Receptor Agonists/administration & dosage
    Adult
    Aged
    Biomarkers/blood
    Bronchodilator Agents/administration & dosage
    Cross-Over Studies
    Double-Blind Method
    Female
    Forced Expiratory Volume
    Glycopyrrolate/administration & dosage
    Health Status
    Humans
    Indans/administration & dosage
    Lung/drug effects
    Male
    Middle Aged
    Muscarinic Antagonists/administration & dosage
    Norway
    Oxygen/blood
    Pulmonary Disease, Chronic Obstructive/blood
    Quinolones/administration & dosage
    Severity of Illness Index
    Surveys and Questionnaires
    Time Factors
    Treatment Outcome
    Vital Capacity
    Journal Article
    Multicenter Study
    Randomized Controlled Trial
    International Journal of Chronic Obstructive Pulmonary Disease
    Źródło:
    International Journal of Chronic Obstructive Pulmonary Disease
    Lehmann, S, Ringbaek, T, Lokke, A, Grote, L, Hedner, J & Lindberg, E 2019, ' A randomized trial to determine the impact of indacaterol/glycopyrronium on nighttime oxygenation and symptoms in patients with moderate-to-severe COPD : the DuoSleep study ', International Journal of Chronic Obstructive Pulmonary Disease, vol. 14, pp. 199-210 . https://doi.org/10.2147/COPD.S184127
    The International Journal of Chronic Obstructive Pulmonary Disease
    International Journal of COPD, Vol Volume 14, Pp 199-210 (2019)
    Lehmann, S, Ringbæk, T, Løkke, A, Grote, L, Hedner, J & Lindberg, E 2019, ' A randomized trial to determine the impact of indacaterol/glycopyrronium on nighttime oxygenation and symptoms in patients with moderate-to-severe COPD : the DuoSleep study ', International Journal of Chronic Obstructive Pulmonary Disease, vol. 14, pp. 199-210 . https://doi.org/10.2147/COPD.S184127
    Opis pliku:
    application/pdf; text/html
    Dostępność:
    https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c48d2846d648e8f2dd6491368b8f863
    http://europepmc.org/articles/PMC6330967
    Szczegóły
    Tytuł:
    Differential anti-ischaemic effects of muscarinic receptor blockade in patients with obstructive coronary artery disease. Impaired vs normal left ventricular function
    Autorzy:
    W. J. Remme
    M. van der Ent
    D. J. Van Veldhuisen
    G. L. Bartels
    A. F. M. Van Den Heuvel
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    Temat:
    Cardiology and Cardiovascular Medicine
    Coronary sinus
    Internal medicine
    medicine.medical_specialty
    medicine
    Atropine
    medicine.drug
    Anesthesia
    Cardiology
    Rate pressure product
    business.industry
    business
    Muscarinic antagonist
    Ventricular pressure
    Coronary artery disease
    medicine.disease
    Heart catheterization
    Heart failure
    Atropine/*administration & dosage
    Biological Markers/blood
    Blood Flow Velocity/drug effects
    Catecholamines/blood
    Comparative Study
    Coronary Angiography
    Coronary Circulation/drug effects
    Coronary Disease/complications/*drug therapy/physiopathology/radiography
    Electrocardiography/drug effects
    Female
    Heart Catheterization
    Humans
    Infusions
    Intravenous
    Lactic Acid/blood
    Male
    Middle Aged
    Muscarinic Antagonists/*administration & dosage
    Myocardium/metabolism
    Stroke Volume/drug effects
    Ventricular Dysfunction
    Left/blood/*complications/drug therapy/physiopathology
    Ventricular Function
    Left/drug effects/*physiology
    Ventricular Pressure/drug effects
    endothelial functionischaemia
    coronary disease
    endothelial function ischaemia
    muscarinic antagonists
    MYOCARDIAL-ISCHEMIA
    HEART-FAILURE
    BLOOD-FLOW
    ACETYLCHOLINE
    VASOCONSTRICTION
    ENDOTHELIUM
    DYSFUNCTION
    ACTIVATION
    Infusions, Intravenous
    Ventricular Dysfunction, Left/blood/*complications/drug therapy/physiopathology
    Ventricular Function, Left/drug effects/*physiology
    Źródło:
    European Heart Journal, 20(23), 1717-1723. Oxford University Press
    European Heart Journal, 20(23), 1717-1723
    Opis pliku:
    application/pdf
    Dostępność:
    https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a988b9783c98c2505653ef41f3f141b3
    http://academic.oup.com/eurheartj/article-pdf/20/23/1717/17882539/1717.pdf
    Szczegóły
    Tytuł:
    Indacaterol and glycopyrronium versus indacaterol on body plethysmography measurements in COPD—a randomised controlled study
    Autorzy:
    Salomon, Joerg
    Stolz, Daiana
    Domenighetti, Guido
    Frey, Jean-Georges
    Turk, Alexander J.
    Azzola, Andrea
    Sigrist, Thomas
    Fitting, Jean-William
    Schmidt, Ulrich
    Geiser, Thomas
    Wild, Corinne
    Kostikas, Konstantinos
    Clemens, Andreas
    Brutsche, Martin
    Pokaż więcej
    Temat:
    Pulmonary and Respiratory Medicine
    610 Medicine & health
    Vital capacity
    Indacaterol
    medicine.drug
    medicine
    Anesthesia
    Bronchodilator
    medicine.drug_class
    FEV1/FVC ratio
    Spirometry
    medicine.diagnostic_test
    COPD
    medicine.disease
    Lung volumes
    Airway resistance
    business.industry
    business
    Adrenergic beta-2 Receptor Agonists/administration & dosage
    Adult
    Aged
    Aged, 80 and over
    Cross-Over Studies
    Diagnosis, Computer-Assisted/methods
    Double-Blind Method
    Drug Combinations
    Female
    Glycopyrrolate/administration & dosage
    Humans
    Indans/administration & dosage
    Male
    Middle Aged
    Muscarinic Antagonists/administration & dosage
    Placebo Effect
    Plethysmography, Whole Body/methods
    Pulmonary Disease, Chronic Obstructive/diagnosis
    Pulmonary Disease, Chronic Obstructive/drug therapy
    Pulmonary Disease, Chronic Obstructive/physiopathology
    Quinolones/administration & dosage
    Reproducibility of Results
    Respiratory Function Tests/methods
    Sensitivity and Specificity
    Spirometry/methods
    Switzerland
    Treatment Outcome
    Body plethysmography
    Glycopyrronium
    Research
    respiratory tract diseases
    biochemical phenomena, metabolism, and nutrition
    Źródło:
    Salomon, Joerg; Stolz, Daiana; Domenighetti, Guido; Frey, Jean-Georges; Turk, Alexander J; Azzola, Andrea; Sigrist, Thomas; Fitting, Jean-William; Schmidt, Ulrich; Geiser, Thomas; Wild, Corinne; Kostikas, Konstantinos; Clemens, Andreas; Brutsche, Martin (2017). Indacaterol and glycopyrronium versus indacaterol on body plethysmography measurements in COPD-a randomised controlled study. Respiratory research, 18(1), p. 13. BioMed Central 10.1186/s12931-016-0498-1 <http://dx.doi.org/10.1186/s12931-016-0498-1>
    Respiratory research, vol. 18, no. 1, pp. 13
    Respiratory Research
    Opis pliku:
    application/pdf
    Dostępność:
    https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6922429012900f149e67ba56981220dc
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