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Wyszukujesz frazę ""Muscle, Smooth, Vascular"" wg kryterium: Temat


Tytuł :
Role of the signal transducer and activator of transcription 3 protein in the proliferation of vascular smooth muscle cells.
Autorzy :
Tang HX; The First People's Hospital of Chenzhou, Institute of Pharmacy and Pharmacology, University of South China, Hunan, China.
Qin XP; The First People's Hospital of Chenzhou, Institute of Pharmacy and Pharmacology, University of South China, Hunan, China.
Li J; The First People's Hospital of Chenzhou, Institute of Pharmacy and Pharmacology, University of South China, Hunan, China.; School of Pharmacy, Southern Medical University, Guangdong, China.
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Źródło :
Vascular [Vascular] 2020 Dec; Vol. 28 (6), pp. 821-828. Date of Electronic Publication: 2020 Jun 02.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Cell Proliferation*
Vascular Remodeling*
Cardiovascular Diseases/*metabolism
Muscle, Smooth, Vascular/*metabolism
Myocytes, Smooth Muscle/*metabolism
STAT3 Transcription Factor/*metabolism
Animals ; Cardiovascular Diseases/pathology ; Cardiovascular Diseases/physiopathology ; Humans ; Muscle, Smooth, Vascular/pathology ; Muscle, Smooth, Vascular/physiopathology ; Myocytes, Smooth Muscle/pathology ; Signal Transduction
Czasopismo naukowe
Tytuł :
The CX3CL1/CX3CR1 axis is upregulated in chronic kidney disease and contributes to angiotensin II-induced migration of vascular smooth muscle cells.
Autorzy :
Li C; Department of General Internal Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China.
Zhong X; Department of Nephrology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China.
Xia W; Class 4, Grade 2, Guangzhou Zhixin High School, Guangzhou 511430, China.
He J; Department of Nephrology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China.
Gan H; Department of Nephrology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China.
Zhao H; Department of Nephrology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China. Electronic address: .
Xia Y; Department of Nephrology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China. Electronic address: .
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Źródło :
Microvascular research [Microvasc Res] 2020 Nov; Vol. 132, pp. 104037. Date of Electronic Publication: 2020 Jun 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Angiotensin II/*pharmacology
CX3C Chemokine Receptor 1/*metabolism
Cell Movement/*drug effects
Chemokine CX3CL1/*metabolism
Muscle, Smooth, Vascular/*drug effects
Myocytes, Smooth Muscle/*drug effects
Renal Insufficiency, Chronic/*metabolism
Uremia/*metabolism
Animals ; Aorta/drug effects ; Aorta/metabolism ; Aorta/pathology ; CX3C Chemokine Receptor 1/genetics ; Cell Line ; Chemokine CX3CL1/genetics ; Disease Models, Animal ; Interleukin-6/metabolism ; Mice, Inbred C57BL ; Muscle, Smooth, Vascular/metabolism ; Muscle, Smooth, Vascular/pathology ; Myocytes, Smooth Muscle/metabolism ; Myocytes, Smooth Muscle/pathology ; Phosphorylation ; Proto-Oncogene Proteins c-akt/metabolism ; Renal Insufficiency, Chronic/pathology ; Signal Transduction ; Up-Regulation ; Uremia/pathology
Czasopismo naukowe
Tytuł :
Activation of M3AChR (Type 3 Muscarinic Acetylcholine Receptor) and Nrf2 (Nuclear Factor Erythroid 2-Related Factor 2) Signaling by Choline Alleviates Vascular Smooth Muscle Cell Phenotypic Switching and Vascular Remodeling.
Autorzy :
He X; Department of Pharmacology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, China.
Deng J; Department of Pharmacology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, China.
Yu XJ; Department of Pharmacology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, China.
Yang S; Department of Pharmacology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, China.
Yang Y; Department of Pharmacology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, China.
Zang WJ; Department of Pharmacology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, China.
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Źródło :
Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2020 Nov; Vol. 40 (11), pp. 2649-2664. Date of Electronic Publication: 2020 Sep 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Plasticity/*drug effects
Choline/*pharmacology
Muscarinic Agonists/*pharmacology
Muscle, Smooth, Vascular/*drug effects
Myocytes, Smooth Muscle/*drug effects
NF-E2-Related Factor 2/*metabolism
Receptor, Muscarinic M3/*agonists
Vascular Remodeling/*drug effects
Animals ; Cell Movement/drug effects ; Cell Proliferation/drug effects ; Cells, Cultured ; Male ; Muscle, Smooth, Vascular/metabolism ; Muscle, Smooth, Vascular/pathology ; Myocytes, Smooth Muscle/metabolism ; Myocytes, Smooth Muscle/pathology ; NF-E2-Related Factor 2/genetics ; Phenotype ; Rats, Sprague-Dawley ; Receptor, Muscarinic M3/genetics ; Receptor, Muscarinic M3/metabolism ; Signal Transduction
Czasopismo naukowe
Tytuł :
The effect of olmesartan on aortic intimal thickening after balloon injury through Apelin/APJ.
Autorzy :
Li Y; Department of Cardiology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong Province 266003,China. Electronic address: .
Guo J; Department of Cardiology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong Province 266003,China.
Yu H; Department of Cardiology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong Province 266003,China.
Zhou J; Department of Emergency Medicine, The Affiliated Hospital of Qingdao University, Qingdao, Shandong Province 266003,China.
Chu X; Department of Cardiology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong Province 266003,China.
Hou B; Department of Cardiology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong Province 266003,China.
Ge J; Department of Cardiology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong Province 266003,China.
Li T; Department of Cardiology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong Province 266003,China.
Duan S; Department of Cardiology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong Province 266003,China.
Xu H; Department of Cardiology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong Province 266003,China.
Yang X; Department of Cardiology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong Province 266003,China.
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Źródło :
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology [Cardiovasc Pathol] 2020 Nov - Dec; Vol. 49, pp. 107230. Date of Electronic Publication: 2020 May 13.
Typ publikacji :
Journal Article
MeSH Terms :
Neointima*
Angiotensin II Type 1 Receptor Blockers/*pharmacology
Apelin/*metabolism
Apelin Receptors/*metabolism
Imidazoles/*pharmacology
Muscle, Smooth, Vascular/*drug effects
Myocytes, Smooth Muscle/*drug effects
Tetrazoles/*pharmacology
Vascular System Injuries/*drug therapy
Angioplasty, Balloon ; Angiotensin II/metabolism ; Animals ; Aorta/drug effects ; Aorta/injuries ; Aorta/metabolism ; Aorta/pathology ; Cell Proliferation/drug effects ; Constriction, Pathologic ; Disease Models, Animal ; Extracellular Signal-Regulated MAP Kinases/metabolism ; Male ; Muscle, Smooth, Vascular/injuries ; Muscle, Smooth, Vascular/metabolism ; Muscle, Smooth, Vascular/pathology ; Myocytes, Smooth Muscle/metabolism ; Myocytes, Smooth Muscle/pathology ; Phosphorylation ; Rats, Wistar ; Receptor, Angiotensin, Type 1/metabolism ; Signal Transduction ; Vascular System Injuries/etiology ; Vascular System Injuries/metabolism ; Vascular System Injuries/pathology
Czasopismo naukowe
Tytuł :
Ruxolitinib attenuates intimal hyperplasia via inhibiting JAK2/STAT3 signaling pathway activation induced by PDGF-BB in vascular smooth muscle cells.
Autorzy :
Song HT; Department of Vascular Surgery, The Second Hospital of Shijiazhuang, Shijiazhuang, China.
Cui Y; Department of Internal Medicine, Affiliated Hospital of Hebei Academy of Chinese Medicine, Shijiazhuang, China.
Zhang LL; Department of Endocrine, The Second Hospital of Shijiazhuang, Shijiazhuang, China.
Cao G; Department of Orthopedic Surgery, The Second Hospital of Shijiazhuang, Shijiazhuang, China.
Li L; Department of Administrative Office, District Center for Disease Control and Prevention of Jizhou, Tianjin, China.
Li G; Department of Vascular Surgery, The Second Hospital of Shijiazhuang, Shijiazhuang, China.
Jia XJ; Department of Endocrine, The First Hospital of Hebei Medical University, Shijiazhuang, China. Electronic address: .
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Źródło :
Microvascular research [Microvasc Res] 2020 Nov; Vol. 132, pp. 104060. Date of Electronic Publication: 2020 Aug 18.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Neointima*
Becaplermin/*pharmacology
Carotid Stenosis/*prevention & control
Janus Kinase 2/*metabolism
Janus Kinase Inhibitors/*pharmacology
Muscle, Smooth, Vascular/*drug effects
Myocytes, Smooth Muscle/*drug effects
Pyrazoles/*pharmacology
STAT3 Transcription Factor/*metabolism
Animals ; Carotid Artery, Common/drug effects ; Carotid Artery, Common/enzymology ; Carotid Artery, Common/pathology ; Carotid Stenosis/enzymology ; Carotid Stenosis/pathology ; Cells, Cultured ; Cyclin D1/metabolism ; Disease Models, Animal ; Hyperplasia ; Male ; Mice, Inbred C57BL ; Muscle, Smooth, Vascular/enzymology ; Muscle, Smooth, Vascular/pathology ; Myocytes, Smooth Muscle/enzymology ; Myocytes, Smooth Muscle/pathology ; Proliferating Cell Nuclear Antigen/metabolism ; Signal Transduction
Czasopismo naukowe
Tytuł :
The role of TRPM7 in vascular calcification: Comparison between phosphate and uremic toxin.
Autorzy :
Lee CT; Division of Nephrology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan. Electronic address: .
Ng HY; Division of Nephrology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.
Kuo WH; Division of Nephrology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.
Tain YL; Division of Nephrology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.
Leung FF; Division of Nephrology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.
Lee YT; Division of Nephrology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.
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Źródło :
Life sciences [Life Sci] 2020 Nov 01; Vol. 260, pp. 118280. Date of Electronic Publication: 2020 Aug 12.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Indican/*pharmacology
Muscle, Smooth, Vascular/*physiology
Myocytes, Smooth Muscle/*physiology
Phosphates/*pharmacology
Protein-Serine-Threonine Kinases/*physiology
TRPM Cation Channels/*physiology
Vascular Calcification/*physiopathology
Bone Morphogenetic Protein 2/analysis ; Bone Morphogenetic Protein 7/analysis ; Cells, Cultured ; Core Binding Factor Alpha 1 Subunit/analysis ; Humans ; Muscle, Smooth, Vascular/chemistry ; Muscle, Smooth, Vascular/drug effects ; Myocytes, Smooth Muscle/chemistry ; Myocytes, Smooth Muscle/drug effects ; Protein-Serine-Threonine Kinases/analysis ; Protein-Serine-Threonine Kinases/antagonists & inhibitors ; Receptors, Calcitriol/analysis ; Renal Insufficiency, Chronic/complications ; TRPM Cation Channels/analysis ; TRPM Cation Channels/antagonists & inhibitors ; Vascular Calcification/chemically induced ; Vascular Calcification/etiology
Czasopismo naukowe
Tytuł :
CircSFMBT2 facilitates vascular smooth muscle cell proliferation by targeting miR-331-3p/HDAC5.
Autorzy :
Luo Y; Department of Clinical Medicine, School of Medicine, Nantong University, Nantong 226001, People's Republic of China.
Huang C; Department of Clinical Medicine, School of Medicine, Nantong University, Nantong 226001, People's Republic of China; Department of Vascular Surgery, Affiliated Hospital of Nantong University, Nantong 226001, People's Republic of China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2021 Jan 01; Vol. 264, pp. 118691. Date of Electronic Publication: 2020 Nov 06.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Proliferation/*physiology
Histone Deacetylases/*metabolism
MicroRNAs/*metabolism
Muscle, Smooth, Vascular/*metabolism
RNA, Circular/*metabolism
Repressor Proteins/*metabolism
Humans ; Muscle, Smooth, Vascular/cytology ; Myocytes, Smooth Muscle/metabolism
Czasopismo naukowe
Tytuł :
Visualization of Spatially-Controlled Vasospasm by Sympathetic Nerve-Mediated ROCK Activation.
Autorzy :
Imanishi A; Laboratory of Bioimaging and Cell Signaling, Graduate School of Biostudies, Kyoto University, Kyoto, Japan.
Ichise H; Laboratory of Bioimaging and Cell Signaling, Graduate School of Biostudies, Kyoto University, Kyoto, Japan.
Fan C; Laboratory of Bioimaging and Cell Signaling, Graduate School of Biostudies, Kyoto University, Kyoto, Japan.
Nakagawa Y; Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Kuwahara K; Department of Cardiovascular Medicine, Shinshu University School of Medicine, Nagano, Japan.
Sumiyama K; Laboratory for Mouse Genetic Engineering, RIKEN Center for Biosystems Dynamics Research, Osaka, Japan.
Matsuda M; Laboratory of Bioimaging and Cell Signaling, Graduate School of Biostudies, Kyoto University, Kyoto, Japan; Department of Pathology and Biology of Diseases, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Terai K; Laboratory of Bioimaging and Cell Signaling, Graduate School of Biostudies, Kyoto University, Kyoto, Japan. Electronic address: .
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Źródło :
The American journal of pathology [Am J Pathol] 2021 Jan; Vol. 191 (1), pp. 194-203. Date of Electronic Publication: 2020 Oct 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Muscle, Smooth, Vascular/*enzymology
Vasoconstriction/*physiology
rho-Associated Kinases/*metabolism
Animals ; Autonomic Nervous System/physiology ; Calcium Signaling/physiology ; Fluorescence Resonance Energy Transfer ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Muscle, Smooth, Vascular/innervation
Czasopismo naukowe
Tytuł :
Impact of the menstrual cycle on peripheral vascular function in premenopausal women: systematic review and meta-analysis.
Autorzy :
Williams JS; Vascular Dynamics Laboratory, Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada.
Dunford EC; Vascular Dynamics Laboratory, Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada.
MacDonald MJ; Vascular Dynamics Laboratory, Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada.
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Źródło :
American journal of physiology. Heart and circulatory physiology [Am J Physiol Heart Circ Physiol] 2020 Dec 01; Vol. 319 (6), pp. H1327-H1337. Date of Electronic Publication: 2020 Oct 16.
Typ publikacji :
Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Hemodynamics*
Menstrual Cycle*/metabolism
Microcirculation*
Premenopause*/metabolism
Endothelium, Vascular/*physiology
Muscle, Smooth, Vascular/*physiology
Adult ; Endothelium, Vascular/metabolism ; Female ; Gonadal Steroid Hormones/metabolism ; Humans ; Muscle, Smooth, Vascular/metabolism ; Signal Transduction ; Young Adult
Czasopismo naukowe
Tytuł :
Long non-coding RNA LOC285194 regulates vascular smooth muscle cell apoptosis in atherosclerosis.
Autorzy :
Cheng Q; Department of Health Care, Qingdao Municipal Hospital (East), Qingdao, Shandong, China.
Zhang M; Department of General surgery, The affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Zhang M; Department of General surgery, The affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Ning L; Department of General surgery, The affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Chen D; Department of General surgery, The affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
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Źródło :
Bioengineered [Bioengineered] 2020 Dec; Vol. 11 (1), pp. 53-60.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis*
Atherosclerosis/*physiopathology
Muscle, Smooth, Vascular/*cytology
RNA, Long Noncoding/*metabolism
Animals ; Apolipoproteins E/genetics ; Apolipoproteins E/metabolism ; Atherosclerosis/genetics ; Atherosclerosis/metabolism ; Cell Movement ; Cell Proliferation ; Female ; Humans ; Male ; Mice ; Mice, Knockout ; Muscle, Smooth, Vascular/metabolism ; RNA, Long Noncoding/genetics
Czasopismo naukowe
Tytuł :
Vascular Smooth Muscle Cell Derived from IPS Cell of Moyamoya Disease - Comparative Characterization with Endothelial Cell Transcriptome.
Autorzy :
Tokairin K; Department of Neurosurgery, Graduate School of Medicine, Hokkaido University, Sapporo, Japan, 060-8638. Electronic address: .
Hamauchi S; Department of Neurosurgery, Graduate School of Medicine, Hokkaido University, Sapporo, Japan, 060-8638. Electronic address: .
Ito M; Department of Neurosurgery, Graduate School of Medicine, Hokkaido University, Sapporo, Japan, 060-8638; Department of Neurosurgery, Kushiro Rosai Hospital, Kushiro, Japan, 085-8533. Electronic address: .
Kazumata K; Department of Neurosurgery, Graduate School of Medicine, Hokkaido University, Sapporo, Japan, 060-8638. Electronic address: .
Sugiyama T; Department of Neurosurgery, Graduate School of Medicine, Hokkaido University, Sapporo, Japan, 060-8638. Electronic address: .
Nakayama N; Department of Neurosurgery, Graduate School of Medicine, Hokkaido University, Sapporo, Japan, 060-8638. Electronic address: .
Kawabori M; Department of Neurosurgery, Graduate School of Medicine, Hokkaido University, Sapporo, Japan, 060-8638.
Osanai T; Department of Neurosurgery, Graduate School of Medicine, Hokkaido University, Sapporo, Japan, 060-8638. Electronic address: .
Houkin K; Department of Neurosurgery, Graduate School of Medicine, Hokkaido University, Sapporo, Japan, 060-8638. Electronic address: .
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Źródło :
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association [J Stroke Cerebrovasc Dis] 2020 Dec; Vol. 29 (12), pp. 105305. Date of Electronic Publication: 2020 Sep 23.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Transcriptome*
Endothelial Cells/*metabolism
Induced Pluripotent Stem Cells/*metabolism
Moyamoya Disease/*genetics
Muscle, Smooth, Vascular/*metabolism
Myocytes, Smooth Muscle/*metabolism
Adult ; Case-Control Studies ; Cell Differentiation ; Cells, Cultured ; Endothelial Cells/pathology ; Female ; Gene Expression Regulation ; Humans ; Induced Pluripotent Stem Cells/pathology ; Male ; Middle Aged ; Moyamoya Disease/metabolism ; Moyamoya Disease/pathology ; Muscle, Smooth, Vascular/pathology ; Myocytes, Smooth Muscle/pathology ; Phenotype ; Signal Transduction
Czasopismo naukowe
Tytuł :
L-type blocker STIMulate Ca entry in synthetic VSMCs.
Autorzy :
Freichel M; Pharmakologisches Institut, Ruprecht-Karls-Universität Heidelberg, 69120, Heidelberg, Germany; DZHK (German Centre for Cardiovascular Research), Partner Site Heidelberg/Mannheim, Heidelberg, 69120, Germany. Electronic address: .
Ottenheijm R; Pharmakologisches Institut, Ruprecht-Karls-Universität Heidelberg, 69120, Heidelberg, Germany; DZHK (German Centre for Cardiovascular Research), Partner Site Heidelberg/Mannheim, Heidelberg, 69120, Germany.
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Źródło :
Cell calcium [Cell Calcium] 2020 Nov; Vol. 91, pp. 102279. Date of Electronic Publication: 2020 Aug 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Comment
MeSH Terms :
Muscle, Smooth, Vascular*/metabolism
Vascular Remodeling*
Calcium/metabolism ; Calcium Channel Blockers ; Calcium Channels, L-Type ; Humans
Czasopismo naukowe
Tytuł :
Long Noncoding RNA Hypoxia-Inducible Factor-1 Alpha-Antisense RNA 1 Regulates Vascular Smooth Muscle Cells to Promote the Development of Thoracic Aortic Aneurysm by Modulating Apoptotic Protease-Activating Factor 1 and Targeting let-7g.
Autorzy :
Zhang X; Department of Cardiac Surgery, Luoyang Central Hospital Affiliated to Zhengzhou University, Luoyang, China.
Li H; Department of Cardiac Surgery, Luoyang Central Hospital Affiliated to Zhengzhou University, Luoyang, China.
Guo X; Department of Cardiac Surgery, Luoyang Central Hospital Affiliated to Zhengzhou University, Luoyang, China.
Hu J; Department of Neonatal Intensive Care Unit, Luoyang Central Hospital Affiliated to Zhengzhou University, Luoyang, China.
Li B; Department of Cardiac Surgery, Luoyang Central Hospital Affiliated to Zhengzhou University, Luoyang, China. Electronic address: .
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Źródło :
The Journal of surgical research [J Surg Res] 2020 Nov; Vol. 255, pp. 602-611. Date of Electronic Publication: 2020 Jul 09.
Typ publikacji :
Journal Article
MeSH Terms :
Aortic Aneurysm, Thoracic/*genetics
Apoptotic Protease-Activating Factor 1/*genetics
MicroRNAs/*metabolism
Muscle, Smooth, Vascular/*pathology
RNA, Long Noncoding/*metabolism
Aorta, Thoracic/cytology ; Aorta, Thoracic/pathology ; Aortic Aneurysm, Thoracic/pathology ; Apoptosis/drug effects ; Apoptosis/genetics ; Apoptotic Protease-Activating Factor 1/metabolism ; Cell Line ; Cell Proliferation/drug effects ; Cell Proliferation/genetics ; Computational Biology ; Extracellular Matrix Proteins/genetics ; Female ; Gene Expression Profiling ; Gene Expression Regulation ; Gene Knockdown Techniques ; Humans ; Male ; MicroRNAs/agonists ; MicroRNAs/antagonists & inhibitors ; Middle Aged ; Muscle, Smooth, Vascular/cytology ; Myocytes, Smooth Muscle/pathology
Czasopismo naukowe
Tytuł :
Diallyl Trisulfide Suppresses Angiotensin II-Induced Vascular Remodeling Via Inhibition of Mitochondrial Fission.
Autorzy :
Lu ZY; Department of Cardiology, The Second Hospital of Shanxi Medical University, 382 Wuyi Road, Taiyuan, 030001, Shanxi, China.
Qi J; Department of Pharmacy, Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, 1665 Kongjiang Road, Shanghai, 200092, China.
Yang B; Department of Cardiology, The Second Hospital of Shanxi Medical University, 382 Wuyi Road, Taiyuan, 030001, Shanxi, China.
Cao HL; Department of Cardiology, The Second Hospital of Shanxi Medical University, 382 Wuyi Road, Taiyuan, 030001, Shanxi, China.
Wang RY; Department of Cardiology, The Second Hospital of Shanxi Medical University, 382 Wuyi Road, Taiyuan, 030001, Shanxi, China.
Wang X; Department of Cardiology, The Second Hospital of Shanxi Medical University, 382 Wuyi Road, Taiyuan, 030001, Shanxi, China.
Chi RF; Department of Cardiology, The Second Hospital of Shanxi Medical University, 382 Wuyi Road, Taiyuan, 030001, Shanxi, China.
Guo CL; Department of Cardiology, The Second Hospital of Shanxi Medical University, 382 Wuyi Road, Taiyuan, 030001, Shanxi, China.
Yang ZM; Department of Cardiology, The Second Hospital of Shanxi Medical University, 382 Wuyi Road, Taiyuan, 030001, Shanxi, China. .
Liu HM; Department of Hematology, The Second Hospital of Shanxi Medical University, 382 Wuyi Road, Taiyuan, 030001, China. .
Li B; Department of Cardiology, The Second Hospital of Shanxi Medical University, 382 Wuyi Road, Taiyuan, 030001, Shanxi, China. .
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Źródło :
Cardiovascular drugs and therapy [Cardiovasc Drugs Ther] 2020 Oct; Vol. 34 (5), pp. 605-618.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Allyl Compounds/*pharmacology
Hypertension/*drug therapy
Mitochondria, Muscle/*drug effects
Mitochondrial Dynamics/*drug effects
Muscle, Smooth, Vascular/*drug effects
Myocytes, Smooth Muscle/*drug effects
Sulfides/*pharmacology
Vascular Remodeling/*drug effects
Angiotensin II ; Animals ; Cell Movement/drug effects ; Cell Plasticity/drug effects ; Cell Proliferation/drug effects ; Cells, Cultured ; Disease Models, Animal ; Dynamins/metabolism ; Hypertension/chemically induced ; Hypertension/metabolism ; Hypertension/physiopathology ; Male ; Mice, Inbred C57BL ; Mitochondria, Muscle/metabolism ; Muscle, Smooth, Vascular/metabolism ; Muscle, Smooth, Vascular/physiopathology ; Myocytes, Smooth Muscle/metabolism ; Phenotype ; Phosphorylation ; Reactive Oxygen Species/metabolism ; Signal Transduction ; rho-Associated Kinases/metabolism
Czasopismo naukowe
Tytuł :
Angiotensin-(1-9) prevents vascular remodeling by decreasing vascular smooth muscle cell dedifferentiation through a FoxO1-dependent mechanism.
Autorzy :
Norambuena-Soto I; Advanced Center for Chronic Diseases (ACCDiS), Faculty of Chemical and Pharmaceutical Sciences & Faculty of Medicine, Universidad de Chile, Santiago, Chile.
Ocaranza MP; Division de Enfermedades Cardiovasculares, Escuela de Medicina, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile; Center of New Drugs for Hypertension (CENDHY), Universidad de Chile & Pontificia Universidad Católica de Chile, Santiago, Chile; Advanced Center for Chronic Diseases (ACCDiS), Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.
Cancino-Arenas N; Advanced Center for Chronic Diseases (ACCDiS), Faculty of Chemical and Pharmaceutical Sciences & Faculty of Medicine, Universidad de Chile, Santiago, Chile.
Sanhueza-Olivares F; Advanced Center for Chronic Diseases (ACCDiS), Faculty of Chemical and Pharmaceutical Sciences & Faculty of Medicine, Universidad de Chile, Santiago, Chile.
Villar-Fincheira P; Advanced Center for Chronic Diseases (ACCDiS), Faculty of Chemical and Pharmaceutical Sciences & Faculty of Medicine, Universidad de Chile, Santiago, Chile.
Leiva-Navarrete S; Advanced Center for Chronic Diseases (ACCDiS), Faculty of Chemical and Pharmaceutical Sciences & Faculty of Medicine, Universidad de Chile, Santiago, Chile.
Mancilla-Medina C; Division de Enfermedades Cardiovasculares, Escuela de Medicina, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile; Center of New Drugs for Hypertension (CENDHY), Universidad de Chile & Pontificia Universidad Católica de Chile, Santiago, Chile.
Moya J; Division de Enfermedades Cardiovasculares, Escuela de Medicina, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile; Center of New Drugs for Hypertension (CENDHY), Universidad de Chile & Pontificia Universidad Católica de Chile, Santiago, Chile.
Novoa U; Departamento de Ciencias Básicas Biomédicas, Facultad de Ciencias de la Salud, Universidad de Talca, Chile.
Jalil JE; Division de Enfermedades Cardiovasculares, Escuela de Medicina, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile; Center of New Drugs for Hypertension (CENDHY), Universidad de Chile & Pontificia Universidad Católica de Chile, Santiago, Chile.
Castro PF; Division de Enfermedades Cardiovasculares, Escuela de Medicina, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile; Advanced Center for Chronic Diseases (ACCDiS), Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.
Lavandero S; Advanced Center for Chronic Diseases (ACCDiS), Faculty of Chemical and Pharmaceutical Sciences & Faculty of Medicine, Universidad de Chile, Santiago, Chile; Corporacion Centro de Estudios Científicos de las Enfermedades Crónicas (CECEC), Santiago, Chile; Department of Internal Medicine (Cardiology Division), University of Texas Southwestern Medical Center, Dallas, USA.
Chiong M; Advanced Center for Chronic Diseases (ACCDiS), Faculty of Chemical and Pharmaceutical Sciences & Faculty of Medicine, Universidad de Chile, Santiago, Chile. Electronic address: .
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Źródło :
Biochemical pharmacology [Biochem Pharmacol] 2020 Oct; Vol. 180, pp. 114190. Date of Electronic Publication: 2020 Aug 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Angiotensin I/*pharmacology
Antihypertensive Agents/*pharmacology
Cell Dedifferentiation/*drug effects
Muscle, Smooth, Vascular/*drug effects
Nerve Tissue Proteins/*antagonists & inhibitors
Vascular Remodeling/*drug effects
Angiotensin I/therapeutic use ; Animals ; Antihypertensive Agents/therapeutic use ; Cell Dedifferentiation/physiology ; Cell Line ; Hypertension/drug therapy ; Hypertension/metabolism ; Male ; Muscle, Smooth, Vascular/cytology ; Muscle, Smooth, Vascular/metabolism ; Nerve Tissue Proteins/metabolism ; Rats ; Rats, Inbred SHR ; Rats, Wistar ; Vascular Remodeling/physiology
Czasopismo naukowe
Tytuł :
Aberrant Exon 8/8a Splicing by Downregulated PTBP (Polypyrimidine Tract-Binding Protein) 1 Increases Ca V 1.2 Dihydropyridine Resistance to Attenuate Vasodilation.
Autorzy :
Lei J; Key Laboratory of Cardiovascular Disease and Molecular Intervention, Department of Physiology, Nanjing Medical University, Jiangsu, China (J.L., M.S., Y.Z., J.F., G.Z., J.W.).
Liu X; Shanghai Chest Hospital, Shanghai Jiaotong University, China (X.L.).
Song M; Key Laboratory of Cardiovascular Disease and Molecular Intervention, Department of Physiology, Nanjing Medical University, Jiangsu, China (J.L., M.S., Y.Z., J.F., G.Z., J.W.).
Zhou Y; Key Laboratory of Cardiovascular Disease and Molecular Intervention, Department of Physiology, Nanjing Medical University, Jiangsu, China (J.L., M.S., Y.Z., J.F., G.Z., J.W.).
Fan J; Key Laboratory of Cardiovascular Disease and Molecular Intervention, Department of Physiology, Nanjing Medical University, Jiangsu, China (J.L., M.S., Y.Z., J.F., G.Z., J.W.).
Shen X; Department of Cardiovascular Surgery, the First Affiliated Hospital of Nanjing Medical University, Jiangsu, China (X.S., X.X.).
Xu X; Department of Cardiovascular Surgery, the First Affiliated Hospital of Nanjing Medical University, Jiangsu, China (X.S., X.X.).
Kapoor I; Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, OH (I.K.).
Zhu G; Key Laboratory of Cardiovascular Disease and Molecular Intervention, Department of Physiology, Nanjing Medical University, Jiangsu, China (J.L., M.S., Y.Z., J.F., G.Z., J.W.).
Wang J; Key Laboratory of Cardiovascular Disease and Molecular Intervention, Department of Physiology, Nanjing Medical University, Jiangsu, China (J.L., M.S., Y.Z., J.F., G.Z., J.W.).
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Źródło :
Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2020 Oct; Vol. 40 (10), pp. 2440-2453. Date of Electronic Publication: 2020 Aug 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Drug Resistance*
Calcium Channel Blockers/*pharmacology
Calcium Channels, L-Type/*drug effects
Heterogeneous-Nuclear Ribonucleoproteins/*metabolism
Hypertension/*drug therapy
Muscle, Smooth, Vascular/*drug effects
Myocytes, Smooth Muscle/*drug effects
Nifedipine/*pharmacology
Polypyrimidine Tract-Binding Protein/*metabolism
Vasodilation/*drug effects
Vasodilator Agents/*pharmacology
Alternative Splicing ; Animals ; Calcium Channels, L-Type/genetics ; Calcium Channels, L-Type/metabolism ; Cell Line, Tumor ; Disease Models, Animal ; Exons ; HEK293 Cells ; Heterogeneous-Nuclear Ribonucleoproteins/genetics ; Humans ; Hypertension/genetics ; Hypertension/metabolism ; Hypertension/physiopathology ; Male ; Membrane Potentials ; Mesenteric Arteries/drug effects ; Mesenteric Arteries/metabolism ; Mesenteric Arteries/physiopathology ; Mice ; Muscle, Smooth, Vascular/metabolism ; Muscle, Smooth, Vascular/physiopathology ; Myocytes, Smooth Muscle/metabolism ; Polypyrimidine Tract-Binding Protein/genetics ; Rats, Inbred SHR ; Rats, Inbred WKY ; Rats, Sprague-Dawley ; Signal Transduction
Czasopismo naukowe
Tytuł :
Metabolism of vascular smooth muscle cells in vascular diseases.
Autorzy :
Shi J; Department of Nephrology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Yang Y; Department of Nephrology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Cheng A; Department of Nephrology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Xu G; Department of Nephrology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
He F; Department of Nephrology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
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Źródło :
American journal of physiology. Heart and circulatory physiology [Am J Physiol Heart Circ Physiol] 2020 Sep 01; Vol. 319 (3), pp. H613-H631. Date of Electronic Publication: 2020 Aug 07.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Energy Metabolism*
Muscle, Smooth, Vascular/*metabolism
Myocytes, Smooth Muscle/*metabolism
Vascular Diseases/*metabolism
Animals ; Cell Movement ; Cell Proliferation ; Cellular Senescence ; Humans ; Muscle, Smooth, Vascular/pathology ; Muscle, Smooth, Vascular/physiopathology ; Myocytes, Smooth Muscle/pathology ; Phenotype ; Prognosis ; Signal Transduction ; Vascular Diseases/pathology ; Vascular Diseases/physiopathology
Czasopismo naukowe
Tytuł :
Nicotine Modulates CTSS (Cathepsin S) Synthesis and Secretion Through Regulating the Autophagy-Lysosomal Machinery in Atherosclerosis.
Autorzy :
Ni H; From the Department of Cardiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, China.
Xu S; From the Department of Cardiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, China.
Chen H; From the Department of Cardiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, China.
Dai Q; From the Department of Cardiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, China.
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Źródło :
Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2020 Sep; Vol. 40 (9), pp. 2054-2069. Date of Electronic Publication: 2020 Jul 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Video-Audio Media
MeSH Terms :
Atherosclerosis/*drug therapy
Autophagy/*drug effects
Cathepsins/*biosynthesis
Lysosomes/*drug effects
Muscle, Smooth, Vascular/*drug effects
Myocytes, Smooth Muscle/*drug effects
Nicotine/*pharmacology
Animals ; Atherosclerosis/enzymology ; Atherosclerosis/genetics ; Atherosclerosis/pathology ; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors/genetics ; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors/metabolism ; Cathepsins/genetics ; Cell Line ; Cell Movement/drug effects ; Disease Models, Animal ; Exocytosis ; Lysosomes/enzymology ; Lysosomes/ultrastructure ; Mechanistic Target of Rapamycin Complex 1/metabolism ; Mice, Knockout, ApoE ; Muscle, Smooth, Vascular/enzymology ; Muscle, Smooth, Vascular/ultrastructure ; Myocytes, Smooth Muscle/enzymology ; Myocytes, Smooth Muscle/ultrastructure ; Secretory Pathway ; Signal Transduction ; rab GTP-Binding Proteins/genetics ; rab GTP-Binding Proteins/metabolism
Czasopismo naukowe
Tytuł :
Estrogen inhibits vascular calcification in rats via hypoxia-induced factor-1α signaling.
Autorzy :
Wu X; Department of Cardiology, First Affiliated Hospital of Dali University, Dali, Yunnan, China.; Yunnan Trans-plateau Cardiovascular Disease of Prevention and Treatment Research Center, Yunnan, China.; Institute of Trans-plateau Cardiovascular Disease Prevention and Treatment of Dali University, Dali, Yunnan, China.
Zhao Q; Department of Cardiology, First Affiliated Hospital of Dali University, Dali, Yunnan, China.
Chen Z; Department of Cardiology, First Affiliated Hospital of Dali University, Dali, Yunnan, China.; Yunnan Trans-plateau Cardiovascular Disease of Prevention and Treatment Research Center, Yunnan, China.; Institute of Trans-plateau Cardiovascular Disease Prevention and Treatment of Dali University, Dali, Yunnan, China.
Geng YJ; Department of Internal Medicine, The Center for Cardiovascular Biology and Atherosclerosis, McGovern School of Medicine, University of Texas Health Science Center at Houston, TX, USA.
Zhang W; Department of Cardiology, First Affiliated Hospital of Dali University, Dali, Yunnan, China.
Zhou Q; Department of Cardiology, First Affiliated Hospital of Dali University, Dali, Yunnan, China.
Yang W; Department of Cardiology, First Affiliated Hospital of Dali University, Dali, Yunnan, China.
Liu Q; Department of Cardiology, First Affiliated Hospital of Dali University, Dali, Yunnan, China.
Liu H; Department of Cardiology, First Affiliated Hospital of Dali University, Dali, Yunnan, China.; Yunnan Trans-plateau Cardiovascular Disease of Prevention and Treatment Research Center, Yunnan, China.; Institute of Trans-plateau Cardiovascular Disease Prevention and Treatment of Dali University, Dali, Yunnan, China.
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Źródło :
Vascular [Vascular] 2020 Aug; Vol. 28 (4), pp. 465-474. Date of Electronic Publication: 2020 Feb 23.
Typ publikacji :
Journal Article
MeSH Terms :
Aortic Diseases/*prevention & control
Estradiol/*pharmacology
Hypoxia-Inducible Factor 1, alpha Subunit/*metabolism
Muscle, Smooth, Vascular/*drug effects
Myocytes, Smooth Muscle/*drug effects
Vascular Calcification/*prevention & control
Animals ; Aorta/drug effects ; Aorta/metabolism ; Aorta/pathology ; Aortic Diseases/genetics ; Aortic Diseases/metabolism ; Aortic Diseases/pathology ; Bone Morphogenetic Protein 2/genetics ; Bone Morphogenetic Protein 2/metabolism ; Cell Line ; Core Binding Factor Alpha 1 Subunit/genetics ; Core Binding Factor Alpha 1 Subunit/metabolism ; Disease Models, Animal ; Female ; Hypoxia-Inducible Factor 1, alpha Subunit/genetics ; Muscle, Smooth, Vascular/metabolism ; Muscle, Smooth, Vascular/pathology ; Myocytes, Smooth Muscle/metabolism ; Myocytes, Smooth Muscle/pathology ; Ovariectomy ; Phosphorylation ; Rats, Sprague-Dawley ; Signal Transduction ; Smad Proteins, Receptor-Regulated/metabolism ; Vascular Calcification/genetics ; Vascular Calcification/metabolism ; Vascular Calcification/pathology
Czasopismo naukowe
Tytuł :
Regulation of the cerebrovascular smooth muscle cell phenotype by mitochondrial oxidative injury and endoplasmic reticulum stress in simulated microgravity rats via the PERK-eIF2α-ATF4-CHOP pathway.
Autorzy :
Zhang R; Department of Cardiology & National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital, Beijing 100853, China.
Jiang M; Department of Cardiology & National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital, Beijing 100853, China.
Zhang J; Department of Cardiology & National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital, Beijing 100853, China.
Qiu Y; Department of Cardiology & National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital, Beijing 100853, China.
Li D; Department of Cardiology & National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital, Beijing 100853, China.
Li S; Department of Cardiology & National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital, Beijing 100853, China.
Liu J; Department of Cardiology & National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital, Beijing 100853, China.
Liu C; Department of Cardiology & National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital, Beijing 100853, China.
Fang Z; Department of Cardiology & National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital, Beijing 100853, China.
Cao F; Department of Cardiology & National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital, Beijing 100853, China. Electronic address: .
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Źródło :
Biochimica et biophysica acta. Molecular basis of disease [Biochim Biophys Acta Mol Basis Dis] 2020 Aug 01; Vol. 1866 (8), pp. 165799. Date of Electronic Publication: 2020 Apr 15.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Activating Transcription Factor 4/*genetics
Cerebral Arteries/*metabolism
Eukaryotic Initiation Factor-2/*genetics
Muscle, Smooth, Vascular/*metabolism
Myocytes, Smooth Muscle/*metabolism
Transcription Factor CHOP/*genetics
eIF-2 Kinase/*genetics
Activating Transcription Factor 4/metabolism ; Animals ; Antioxidants/pharmacology ; Cerebral Arteries/cytology ; Cerebral Arteries/drug effects ; Endoplasmic Reticulum/drug effects ; Endoplasmic Reticulum/genetics ; Endoplasmic Reticulum/metabolism ; Eukaryotic Initiation Factor-2/metabolism ; Gene Expression Regulation ; Heat-Shock Proteins/genetics ; Heat-Shock Proteins/metabolism ; Hindlimb Suspension ; Male ; Mitochondria/drug effects ; Mitochondria/genetics ; Mitochondria/metabolism ; Muscle, Smooth, Vascular/cytology ; Muscle, Smooth, Vascular/drug effects ; Myocytes, Smooth Muscle/cytology ; Myocytes, Smooth Muscle/drug effects ; Organophosphorus Compounds/pharmacology ; Phenylbutyrates/pharmacology ; Phosphatidylinositol 3-Kinases/genetics ; Phosphatidylinositol 3-Kinases/metabolism ; Piperidines/pharmacology ; Proto-Oncogene Proteins c-akt/genetics ; Proto-Oncogene Proteins c-akt/metabolism ; Rats ; Rats, Sprague-Dawley ; Signal Transduction ; TOR Serine-Threonine Kinases/genetics ; TOR Serine-Threonine Kinases/metabolism ; Taurochenodeoxycholic Acid/pharmacology ; Transcription Factor CHOP/metabolism ; eIF-2 Kinase/metabolism
Czasopismo naukowe

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