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Wyszukujesz frazę ""Muscle, Smooth, Vascular"" wg kryterium: Temat


Tytuł :
PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) Triggers Vascular Smooth Muscle Cell Senescence and Apoptosis: Implication of Its Direct Role in Degenerative Vascular Disease.
Autorzy :
Guo Y; Departments of Biochemistry and Molecular Biology and Physiology and Pharmacology (Y. Guo, Z.T., B.Y., H.Y., Y. Gui, X.-L. Zheng).; Department of Cardiology, the Second Xiangya Hospital of Central South University, Changsha, China (Y. Guo, S.T., S.Z.).
Tang Z; Departments of Biochemistry and Molecular Biology and Physiology and Pharmacology (Y. Guo, Z.T., B.Y., H.Y., Y. Gui, X.-L. Zheng).; Institute of Cardiovascular Disease, Key Laboratory for Arteriosclerology of Hunan Province, Hunan International Scientific and Technological Cooperation Base of Arteriosclerotic Disease, School of Basic Medical Sciences, Hengyang Medical School, University of South China, Hengyang, Hunan (Z.T., B.Y., J.P., Y.C.).
Yan B; Departments of Biochemistry and Molecular Biology and Physiology and Pharmacology (Y. Guo, Z.T., B.Y., H.Y., Y. Gui, X.-L. Zheng).; Institute of Cardiovascular Disease, Key Laboratory for Arteriosclerology of Hunan Province, Hunan International Scientific and Technological Cooperation Base of Arteriosclerotic Disease, School of Basic Medical Sciences, Hengyang Medical School, University of South China, Hengyang, Hunan (Z.T., B.Y., J.P., Y.C.).
Yin H; Departments of Biochemistry and Molecular Biology and Physiology and Pharmacology (Y. Guo, Z.T., B.Y., H.Y., Y. Gui, X.-L. Zheng).; Now with Robarts Research Institute, Schulich School of Medicine and Dentistry, Western University, London, Canada (H.Y.).
Tai S; Department of Cardiology, the Second Xiangya Hospital of Central South University, Changsha, China (Y. Guo, S.T., S.Z.).
Peng J; Institute of Cardiovascular Disease, Key Laboratory for Arteriosclerology of Hunan Province, Hunan International Scientific and Technological Cooperation Base of Arteriosclerotic Disease, School of Basic Medical Sciences, Hengyang Medical School, University of South China, Hengyang, Hunan (Z.T., B.Y., J.P., Y.C.).
Cui Y; Departments of Biochemistry and Molecular Biology and Physiology and Pharmacology (Y. Guo, Z.T., B.Y., H.Y., Y. Gui, X.-L. Zheng).; Institute of Cardiovascular Disease, Key Laboratory for Arteriosclerology of Hunan Province, Hunan International Scientific and Technological Cooperation Base of Arteriosclerotic Disease, School of Basic Medical Sciences, Hengyang Medical School, University of South China, Hengyang, Hunan (Z.T., B.Y., J.P., Y.C.).
Gui Y; Departments of Biochemistry and Molecular Biology and Physiology and Pharmacology (Y. Guo, Z.T., B.Y., H.Y., Y. Gui, X.-L. Zheng).
Belke D; Departments of Biochemistry and Molecular Biology and Physiology and Pharmacology (Y. Guo, Z.T., B.Y., H.Y., Y. Gui, X.-L. Zheng).
Zhou S; Department of Cardiology, the Second Xiangya Hospital of Central South University, Changsha, China (Y. Guo, S.T., S.Z.).
Zheng XL; Departments of Biochemistry and Molecular Biology and Physiology and Pharmacology (Y. Guo, Z.T., B.Y., H.Y., Y. Gui, X.-L. Zheng).
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Źródło :
Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2022 Jan; Vol. 42 (1), pp. 67-86. Date of Electronic Publication: 2021 Nov 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Apoptosis*
Cell Proliferation*
Cellular Senescence*
Atherosclerosis/*enzymology
Muscle, Smooth, Vascular/*enzymology
Myocytes, Smooth Muscle/*enzymology
Proprotein Convertase 9/*metabolism
Animals ; Atherosclerosis/genetics ; Atherosclerosis/pathology ; Atherosclerosis/physiopathology ; Cells, Cultured ; Female ; Humans ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Muscle, Smooth, Vascular/pathology ; Muscle, Smooth, Vascular/physiopathology ; Myocytes, Smooth Muscle/pathology ; Neointima ; Plaque, Atherosclerotic ; Proprotein Convertase 9/genetics ; Signal Transduction ; Vascular Stiffness
Czasopismo naukowe
Tytuł :
Nicotinate-curcumin inhibits AngII-induced vascular smooth muscle cell phenotype switching by upregulating Daxx expression.
Autorzy :
Sun SY; School of Pharmacy, Hunan University of Chinese Medicine, Changsha, China.; The Cardiovascular Research Center, The First Affiliated Hospital of Xinxiang Medical University, Xinxiang, Henan, China.
Cao YM; School of Pharmacy, Hunan University of Chinese Medicine, Changsha, China.
Huo YJ; School of Pharmacy, Hunan University of Chinese Medicine, Changsha, China.
Qiu F; School of Pharmacy, Hunan University of Chinese Medicine, Changsha, China.; Department of pharmacy, The First Affiliated Hospital of Hunan University of Medicine, Huaihua, Hunan, China.
Quan WJ; School of Pharmacy, Hunan University of Chinese Medicine, Changsha, China.
He CP; School of Pharmacy, Hunan University of Chinese Medicine, Changsha, China.
Chen Y; School of Pharmacy, Hunan University of Chinese Medicine, Changsha, China.
Liao DF; School of Pharmacy, Hunan University of Chinese Medicine, Changsha, China.
Tuo QH; School of Pharmacy, Hunan University of Chinese Medicine, Changsha, China.; School of Medicine, Hunan University of Chinese Medicine, Changsha, China.
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Źródło :
Cell adhesion & migration [Cell Adh Migr] 2021 Dec; Vol. 15 (1), pp. 116-125.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Phenotype*
Co-Repressor Proteins/*metabolism
Curcumin/*analogs & derivatives
Molecular Chaperones/*metabolism
Muscle, Smooth, Vascular/*drug effects
Myocytes, Smooth Muscle/*drug effects
Niacin/*analogs & derivatives
Atherosclerosis/prevention & control ; Cell Movement/drug effects ; Cell Proliferation/drug effects ; Cells, Cultured ; Curcumin/chemistry ; Curcumin/pharmacology ; Humans ; Muscle, Smooth, Vascular/metabolism ; Muscle, Smooth, Vascular/pathology ; Myocytes, Smooth Muscle/metabolism ; Myocytes, Smooth Muscle/pathology ; Niacin/chemistry ; Niacin/pharmacology ; PTEN Phosphohydrolase/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Signal Transduction/drug effects ; Up-Regulation
Czasopismo naukowe
Tytuł :
Inhibition of Vascular Growth by Modulation of the Anandamide/Fatty Acid Amide Hydrolase Axis.
Autorzy :
Rieck S; Institute of Physiology I, Life&Brain Center, Medical Faculty (S.R., S.K., B.K.F., D.W.), University of Bonn, Germany.
Kilgus S; Institute of Physiology I, Life&Brain Center, Medical Faculty (S.R., S.K., B.K.F., D.W.), University of Bonn, Germany.
Meyer JH; Department of Ophthalmology (J.H.M., S.S.-V.), University of Bonn, Germany.
Huang H; Department of Biomedical Sciences, City University of Hong Kong (H.H., L.Z., X.W.).
Zhao L; Department of Biomedical Sciences, City University of Hong Kong (H.H., L.Z., X.W.).
Matthey M; Department of Systems Physiology, Institute of Physiology, Medical Faculty, Ruhr University of Bochum, Germany (M.M., D.W.).
Wang X; Department of Biomedical Sciences, City University of Hong Kong (H.H., L.Z., X.W.).
Schmitz-Valckenberg S; Department of Ophthalmology (J.H.M., S.S.-V.), University of Bonn, Germany.; John A. Moran Eye Center, Ophthalmology & Visual Science, University of Utah, Salt Lake City (S.S.-V.).
Fleischmann BK; Institute of Physiology I, Life&Brain Center, Medical Faculty (S.R., S.K., B.K.F., D.W.), University of Bonn, Germany.
Wenzel D; Institute of Physiology I, Life&Brain Center, Medical Faculty (S.R., S.K., B.K.F., D.W.), University of Bonn, Germany.; Department of Systems Physiology, Institute of Physiology, Medical Faculty, Ruhr University of Bochum, Germany (M.M., D.W.).
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Źródło :
Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2021 Dec; Vol. 41 (12), pp. 2974-2989. Date of Electronic Publication: 2021 Oct 07.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Amidohydrolases/*pharmacokinetics
Arachidonic Acids/*pharmacology
Blood Vessels/*drug effects
Endocannabinoids/*pharmacology
Endothelium, Vascular/*growth & development
Muscle, Smooth, Vascular/*drug effects
Polyunsaturated Alkamides/*pharmacology
Animals ; Blood Vessels/growth & development ; Blood Vessels/pathology ; Cannabinoid Receptor Agonists/pharmacology ; Cattle ; Cell Line ; Disease Models, Animal ; Endothelium, Vascular/drug effects ; Endothelium, Vascular/pathology ; Humans ; Mice ; Muscle, Smooth, Vascular/metabolism ; Muscle, Smooth, Vascular/pathology ; Neovascularization, Pathologic
Czasopismo naukowe
Tytuł :
TRPC6, a therapeutic target for pulmonary hypertension.
Autorzy :
Jain PP; Section of Physiology, University of California, San Diego, La Jolla, California.; Division of Pulmonary, Critical Care and Sleep Medicine, University of California, San Diego, La Jolla, California.
Lai N; Section of Physiology, University of California, San Diego, La Jolla, California.; State Key Laboratory of Respiratory Medicine and First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Xiong M; Section of Physiology, University of California, San Diego, La Jolla, California.; State Key Laboratory of Respiratory Medicine and First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Chen J; Section of Physiology, University of California, San Diego, La Jolla, California.; State Key Laboratory of Respiratory Medicine and First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Babicheva A; Section of Physiology, University of California, San Diego, La Jolla, California.; Division of Pulmonary, Critical Care and Sleep Medicine, University of California, San Diego, La Jolla, California.
Zhao T; Section of Physiology, University of California, San Diego, La Jolla, California.; Division of Pulmonary, Critical Care and Sleep Medicine, University of California, San Diego, La Jolla, California.
Parmisano S; Section of Physiology, University of California, San Diego, La Jolla, California.
Zhao M; Section of Physiology, University of California, San Diego, La Jolla, California.
Paquin C; Section of Physiology, University of California, San Diego, La Jolla, California.
Matti M; Section of Physiology, University of California, San Diego, La Jolla, California.
Powers R; Section of Physiology, University of California, San Diego, La Jolla, California.
Balistrieri A; Section of Physiology, University of California, San Diego, La Jolla, California.; Division of Pulmonary, Critical Care and Sleep Medicine, University of California, San Diego, La Jolla, California.
Kim NH; Division of Pulmonary, Critical Care and Sleep Medicine, University of California, San Diego, La Jolla, California.
Valdez-Jasso D; Department of Bioengineering, University of California, San Diego, La Jolla, California.
Thistlethwaite PA; Division of Cardiothoracic Surgery, Department of Surgery, University of California, San Diego, La Jolla, California.
Shyy JY; Division of Cardiovascular Medicine, University of California, San Diego, La Jolla, California.
Wang J; Section of Physiology, University of California, San Diego, La Jolla, California.; State Key Laboratory of Respiratory Medicine and First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Garcia JGN; Department of Medicine, The University of Arizona, Tucson, Arizona.
Makino A; Division of Endocrinology and Metabolism, Department of Medicine, University of California, San Diego, La Jolla, California.
Yuan JX; Section of Physiology, University of California, San Diego, La Jolla, California.; Division of Pulmonary, Critical Care and Sleep Medicine, University of California, San Diego, La Jolla, California.
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Źródło :
American journal of physiology. Lung cellular and molecular physiology [Am J Physiol Lung Cell Mol Physiol] 2021 Dec 01; Vol. 321 (6), pp. L1161-L1182. Date of Electronic Publication: 2021 Oct 27.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Vasoconstriction*
Gene Expression Regulation/*drug effects
Hypertension, Pulmonary/*pathology
Muscle, Smooth, Vascular/*pathology
Pulmonary Artery/*pathology
TRPC6 Cation Channel/*metabolism
Animals ; Boron Compounds/pharmacology ; Calcium Signaling ; Cells, Cultured ; Humans ; Hypertension, Pulmonary/drug therapy ; Hypertension, Pulmonary/metabolism ; Mice ; Muscle, Smooth, Vascular/drug effects ; Muscle, Smooth, Vascular/metabolism ; Phosphatidylinositol 3-Kinases/genetics ; Phosphatidylinositol 3-Kinases/metabolism ; Pulmonary Artery/drug effects ; Pulmonary Artery/metabolism ; TOR Serine-Threonine Kinases/genetics ; TOR Serine-Threonine Kinases/metabolism ; TRPC6 Cation Channel/antagonists & inhibitors ; TRPC6 Cation Channel/genetics
Czasopismo naukowe
Tytuł :
Amentoflavone prevents ox-LDL-induced lipid accumulation by suppressing the PPARγ/CD36 signal pathway.
Autorzy :
Zhuang JL; Department of Laboratory Medicine, Guangdong Provincial Hospital of Chinese Medicine, Zhuhai 519015, China.
Liu YY; Second Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou 510120, China.
Li ZZ; Panyu Hospital of Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou 510120, China.
Zhuang QZ; Second Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou 510120, China.
Tang WZ; Department of Laboratory Medicine, Guangdong Provincial Hospital of Chinese Medicine, Zhuhai 519015, China.
Xiong Y; Panyu Hospital of Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou 510120, China. Electronic address: .
Huang XZ; Department of Laboratory Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510120, China. Electronic address: .
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Źródło :
Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 2021 Nov 15; Vol. 431, pp. 115733. Date of Electronic Publication: 2021 Sep 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Atherosclerosis/*prevention & control
Biflavonoids/*pharmacology
CD36 Antigens/*metabolism
Foam Cells/*drug effects
Hypolipidemic Agents/*pharmacology
Lipid Metabolism/*drug effects
Lipoproteins, LDL/*toxicity
Muscle, Smooth, Vascular/*drug effects
Myocytes, Smooth Muscle/*drug effects
PPAR gamma/*metabolism
ATP Binding Cassette Transporter 1/metabolism ; Atherosclerosis/genetics ; Atherosclerosis/metabolism ; Atherosclerosis/pathology ; CD36 Antigens/genetics ; Foam Cells/metabolism ; Foam Cells/pathology ; Humans ; Muscle, Smooth, Vascular/metabolism ; Muscle, Smooth, Vascular/pathology ; Myocytes, Smooth Muscle/metabolism ; Myocytes, Smooth Muscle/pathology ; PPAR gamma/genetics ; Plaque, Atherosclerotic ; Signal Transduction ; THP-1 Cells
Czasopismo naukowe
Tytuł :
Dextromethorphan Reduces Oxidative Stress and Inhibits Uremic Artery Calcification.
Autorzy :
Liu ES; Division of Cardiology, Kaohsiung Veterans General Hospital, Kaohsiung 813779, Taiwan.; Institutes of Clinical Medicine, National Yang Ming Chiao Tung University, Hsinchu City 30010, Taiwan.
Chen NC; Department of Neurology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung 813779, Taiwan.
Jao TM; Divisions of Medical Research, Kaohsiung Veterans General Hospital, Kaohsiung 813779, Taiwan.; Institution of Precision Medicine, National Sun Yat-sen University, Kaohsiung 813779, Taiwan.
Chen CL; Institutes of Clinical Medicine, National Yang Ming Chiao Tung University, Hsinchu City 30010, Taiwan.; Divisions of Medical Research, Kaohsiung Veterans General Hospital, Kaohsiung 813779, Taiwan.; Institution of Precision Medicine, National Sun Yat-sen University, Kaohsiung 813779, Taiwan.; Divisions of Nephrology, Kaohsiung Veterans General Hospital, Kaohsiung 813779, Taiwan.; Faculty of Medicine, School of Medicine, National Yang Ming Chiao Tung University, Hsinchu City 30010, Taiwan.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Nov 13; Vol. 22 (22). Date of Electronic Publication: 2021 Nov 13.
Typ publikacji :
Journal Article
MeSH Terms :
Muscle, Smooth, Vascular*/metabolism
Muscle, Smooth, Vascular*/pathology
Myocytes, Smooth Muscle*/metabolism
Myocytes, Smooth Muscle*/pathology
Uremia*/drug therapy
Uremia*/metabolism
Uremia*/pathology
Vascular Calcification*/drug therapy
Vascular Calcification*/metabolism
Vascular Calcification*/pathology
Dextromethorphan/*pharmacology
Oxidative Stress/*drug effects
Animals ; Cell Line ; Humans ; Male ; Rats ; Rats, Inbred WKY
Czasopismo naukowe
Tytuł :
Dihydromyricetin ameliorates vascular calcification in chronic kidney disease by targeting AKT signaling.
Autorzy :
Feng L; Department of Cardiology, Laboratory of Heart Center, Zhujiang Hospital, Southern Medical University, Guangzhou, P.R. China.; Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, Guangzhou, P.R. China.; Sino-Japanese Cooperation Platform for Translational Research in Heart Failure, Zhujiang Hospital, Southern Medical University, Guangzhou, P.R. China.
Que D; Department of Cardiology, Laboratory of Heart Center, Zhujiang Hospital, Southern Medical University, Guangzhou, P.R. China.; Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, Guangzhou, P.R. China.; Sino-Japanese Cooperation Platform for Translational Research in Heart Failure, Zhujiang Hospital, Southern Medical University, Guangzhou, P.R. China.
Li Z; Department of Cardiology, Laboratory of Heart Center, Zhujiang Hospital, Southern Medical University, Guangzhou, P.R. China.; Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, Guangzhou, P.R. China.; Sino-Japanese Cooperation Platform for Translational Research in Heart Failure, Zhujiang Hospital, Southern Medical University, Guangzhou, P.R. China.
Zhong X; Department of Cardiology, Laboratory of Heart Center, Zhujiang Hospital, Southern Medical University, Guangzhou, P.R. China.; Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, Guangzhou, P.R. China.; Sino-Japanese Cooperation Platform for Translational Research in Heart Failure, Zhujiang Hospital, Southern Medical University, Guangzhou, P.R. China.
Yan J; Department of Cardiology, Laboratory of Heart Center, Zhujiang Hospital, Southern Medical University, Guangzhou, P.R. China.; Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, Guangzhou, P.R. China.; Sino-Japanese Cooperation Platform for Translational Research in Heart Failure, Zhujiang Hospital, Southern Medical University, Guangzhou, P.R. China.
Wei J; Department of Cardiology, Laboratory of Heart Center, Zhujiang Hospital, Southern Medical University, Guangzhou, P.R. China.; Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, Guangzhou, P.R. China.; Sino-Japanese Cooperation Platform for Translational Research in Heart Failure, Zhujiang Hospital, Southern Medical University, Guangzhou, P.R. China.
Zhang X; Department of Cardiology, Laboratory of Heart Center, Zhujiang Hospital, Southern Medical University, Guangzhou, P.R. China.; Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, Guangzhou, P.R. China.; Sino-Japanese Cooperation Platform for Translational Research in Heart Failure, Zhujiang Hospital, Southern Medical University, Guangzhou, P.R. China.
Yang P; Department of Cardiology, Laboratory of Heart Center, Zhujiang Hospital, Southern Medical University, Guangzhou, P.R. China.; Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, Guangzhou, P.R. China.; Sino-Japanese Cooperation Platform for Translational Research in Heart Failure, Zhujiang Hospital, Southern Medical University, Guangzhou, P.R. China.
Ou C; Department of Cardiology, Laboratory of Heart Center, Zhujiang Hospital, Southern Medical University, Guangzhou, P.R. China.; Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, Guangzhou, P.R. China.; Sino-Japanese Cooperation Platform for Translational Research in Heart Failure, Zhujiang Hospital, Southern Medical University, Guangzhou, P.R. China.
Chen M; Department of Cardiology, Laboratory of Heart Center, Zhujiang Hospital, Southern Medical University, Guangzhou, P.R. China.; Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, Guangzhou, P.R. China.; Sino-Japanese Cooperation Platform for Translational Research in Heart Failure, Zhujiang Hospital, Southern Medical University, Guangzhou, P.R. China.
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Źródło :
Clinical science (London, England : 1979) [Clin Sci (Lond)] 2021 Nov 12; Vol. 135 (21), pp. 2483-2502.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Aortic Diseases/*prevention & control
Flavonols/*pharmacology
Muscle, Smooth, Vascular/*drug effects
Myocytes, Smooth Muscle/*drug effects
Osteogenesis/*drug effects
Proto-Oncogene Proteins c-akt/*metabolism
Renal Insufficiency, Chronic/*drug therapy
Vascular Calcification/*prevention & control
Animals ; Aorta/drug effects ; Aorta/enzymology ; Aorta/pathology ; Aortic Diseases/enzymology ; Aortic Diseases/etiology ; Aortic Diseases/pathology ; Cells, Cultured ; Disease Models, Animal ; Humans ; Male ; Muscle, Smooth, Vascular/enzymology ; Muscle, Smooth, Vascular/pathology ; Myocytes, Smooth Muscle/enzymology ; Myocytes, Smooth Muscle/pathology ; Phosphorylation ; Proto-Oncogene Proteins c-akt/genetics ; Rats, Sprague-Dawley ; Renal Insufficiency, Chronic/complications ; Renal Insufficiency, Chronic/enzymology ; Renal Insufficiency, Chronic/pathology ; Signal Transduction ; Vascular Calcification/enzymology ; Vascular Calcification/etiology ; Vascular Calcification/pathology
Czasopismo naukowe
Tytuł :
Interleukin 6 reduces vascular smooth muscle cell apoptosis via Prep1 and is associated with aging.
Autorzy :
Cimmino I; Department of Translational Medicine, Federico II University of Naples and URT 'Genomic of Diabetes' of Institute of Experimental Endocrinology and Oncology, National Council of Research (CNR), Naples, Italy.
Prisco F; Department of Veterinary Medicine and Animal Production, Federico II University of Naples, Naples, Italy.
Orso S; Department of Translational Medicine, Federico II University of Naples and URT 'Genomic of Diabetes' of Institute of Experimental Endocrinology and Oncology, National Council of Research (CNR), Naples, Italy.
Agognon AL; Department of Translational Medicine, Federico II University of Naples and URT 'Genomic of Diabetes' of Institute of Experimental Endocrinology and Oncology, National Council of Research (CNR), Naples, Italy.
Liguoro P; Department of Translational Medicine, Federico II University of Naples and URT 'Genomic of Diabetes' of Institute of Experimental Endocrinology and Oncology, National Council of Research (CNR), Naples, Italy.
De Biase D; Department of Veterinary Medicine and Animal Production, Federico II University of Naples, Naples, Italy.
Doti N; Institute of Biostructure and Bioimaging, National Research Council and Interuniversity Research Centre on Bioactive Peptides Naples, Naples, Italy.
Ruvo M; Institute of Biostructure and Bioimaging, National Research Council and Interuniversity Research Centre on Bioactive Peptides Naples, Naples, Italy.
Paciello O; Department of Veterinary Medicine and Animal Production, Federico II University of Naples, Naples, Italy.
Beguinot F; Department of Translational Medicine, Federico II University of Naples and URT 'Genomic of Diabetes' of Institute of Experimental Endocrinology and Oncology, National Council of Research (CNR), Naples, Italy.
Formisano P; Department of Translational Medicine, Federico II University of Naples and URT 'Genomic of Diabetes' of Institute of Experimental Endocrinology and Oncology, National Council of Research (CNR), Naples, Italy.
Oriente F; Department of Translational Medicine, Federico II University of Naples and URT 'Genomic of Diabetes' of Institute of Experimental Endocrinology and Oncology, National Council of Research (CNR), Naples, Italy.
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Źródło :
FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2021 Nov; Vol. 35 (11), pp. e21989.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Muscle, Smooth, Vascular*/cytology
Muscle, Smooth, Vascular*/metabolism
Myocytes, Smooth Muscle*/cytology
Myocytes, Smooth Muscle*/metabolism
Aging/*metabolism
Homeodomain Proteins/*physiology
Interleukin-6/*physiology
Animals ; Apoptosis ; Cells, Cultured ; Mice ; Mice, Inbred C57BL
Czasopismo naukowe
Tytuł :
Nkx2-3 induces autophagy inhibiting proliferation and migration of vascular smooth muscle cells via AMPK/mTOR signaling pathway.
Autorzy :
Zheng H; Department of Cardiology, Laboratory of Heart Center, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China.; Heart Center of Zhujiang Hospital, Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, Guangzhou, Guangdong, China.; Heart Center of Zhujiang Hospital, Sino-Japanese Cooperation Platform for Translational Research in Heart Failure, Guangzhou, Guangdong, China.
Zhai W; Department of Cardiology, Laboratory of Heart Center, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China.; Heart Center of Zhujiang Hospital, Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, Guangzhou, Guangdong, China.; Heart Center of Zhujiang Hospital, Sino-Japanese Cooperation Platform for Translational Research in Heart Failure, Guangzhou, Guangdong, China.
Zhong C; Department of Cardiology, Laboratory of Heart Center, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China.; Heart Center of Zhujiang Hospital, Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, Guangzhou, Guangdong, China.; Heart Center of Zhujiang Hospital, Sino-Japanese Cooperation Platform for Translational Research in Heart Failure, Guangzhou, Guangdong, China.
Hong Q; Department of Cardiology, Laboratory of Heart Center, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China.; Heart Center of Zhujiang Hospital, Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, Guangzhou, Guangdong, China.; Heart Center of Zhujiang Hospital, Sino-Japanese Cooperation Platform for Translational Research in Heart Failure, Guangzhou, Guangdong, China.
Li H; Department of Cardiology, Laboratory of Heart Center, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China.; Heart Center of Zhujiang Hospital, Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, Guangzhou, Guangdong, China.; Heart Center of Zhujiang Hospital, Sino-Japanese Cooperation Platform for Translational Research in Heart Failure, Guangzhou, Guangdong, China.
Rui B; Department of Cardiology, Laboratory of Heart Center, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China.; Heart Center of Zhujiang Hospital, Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, Guangzhou, Guangdong, China.; Heart Center of Zhujiang Hospital, Sino-Japanese Cooperation Platform for Translational Research in Heart Failure, Guangzhou, Guangdong, China.
Zhu X; Department of Cardiology, Laboratory of Heart Center, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China.; Heart Center of Zhujiang Hospital, Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, Guangzhou, Guangdong, China.; Heart Center of Zhujiang Hospital, Sino-Japanese Cooperation Platform for Translational Research in Heart Failure, Guangzhou, Guangdong, China.
Que D; Department of Cardiology, Laboratory of Heart Center, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China.; Heart Center of Zhujiang Hospital, Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, Guangzhou, Guangdong, China.; Heart Center of Zhujiang Hospital, Sino-Japanese Cooperation Platform for Translational Research in Heart Failure, Guangzhou, Guangdong, China.
Feng L; Department of Cardiology, Laboratory of Heart Center, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China.; Heart Center of Zhujiang Hospital, Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, Guangzhou, Guangdong, China.; Heart Center of Zhujiang Hospital, Sino-Japanese Cooperation Platform for Translational Research in Heart Failure, Guangzhou, Guangdong, China.
Yu B; Department of Cardiology, Laboratory of Heart Center, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China.; Heart Center of Zhujiang Hospital, Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, Guangzhou, Guangdong, China.; Heart Center of Zhujiang Hospital, Sino-Japanese Cooperation Platform for Translational Research in Heart Failure, Guangzhou, Guangdong, China.
Huang G; Department of Cardiology, Laboratory of Heart Center, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China.; Heart Center of Zhujiang Hospital, Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, Guangzhou, Guangdong, China.; Heart Center of Zhujiang Hospital, Sino-Japanese Cooperation Platform for Translational Research in Heart Failure, Guangzhou, Guangdong, China.
Yin J; Department of Cardiology, Laboratory of Heart Center, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China.; Heart Center of Zhujiang Hospital, Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, Guangzhou, Guangdong, China.; Heart Center of Zhujiang Hospital, Sino-Japanese Cooperation Platform for Translational Research in Heart Failure, Guangzhou, Guangdong, China.
Li J; Department of Cardiology, Laboratory of Heart Center, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China.; Heart Center of Zhujiang Hospital, Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, Guangzhou, Guangdong, China.; Heart Center of Zhujiang Hospital, Sino-Japanese Cooperation Platform for Translational Research in Heart Failure, Guangzhou, Guangdong, China.
Yan J; Department of Cardiology, Laboratory of Heart Center, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China.; Heart Center of Zhujiang Hospital, Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, Guangzhou, Guangdong, China.; Heart Center of Zhujiang Hospital, Sino-Japanese Cooperation Platform for Translational Research in Heart Failure, Guangzhou, Guangdong, China.
Yang P; Department of Cardiology, Laboratory of Heart Center, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China.; Heart Center of Zhujiang Hospital, Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, Guangzhou, Guangdong, China.; Heart Center of Zhujiang Hospital, Sino-Japanese Cooperation Platform for Translational Research in Heart Failure, Guangzhou, Guangdong, China.
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Źródło :
Journal of cellular physiology [J Cell Physiol] 2021 Nov; Vol. 236 (11), pp. 7342-7355. Date of Electronic Publication: 2021 Apr 30.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Autophagy*/drug effects
Cell Movement*/drug effects
Cell Proliferation*/drug effects
AMP-Activated Protein Kinases/*metabolism
Carotid Artery Injuries/*enzymology
Muscle, Smooth, Vascular/*enzymology
Myocytes, Smooth Muscle/*enzymology
TOR Serine-Threonine Kinases/*metabolism
Animals ; Becaplermin/pharmacology ; Carotid Artery Injuries/genetics ; Carotid Artery Injuries/pathology ; Carotid Artery Injuries/prevention & control ; Cells, Cultured ; Disease Models, Animal ; Male ; Muscle, Smooth, Vascular/drug effects ; Muscle, Smooth, Vascular/ultrastructure ; Myocytes, Smooth Muscle/drug effects ; Myocytes, Smooth Muscle/ultrastructure ; Neointima ; Rats, Sprague-Dawley ; Signal Transduction ; Vascular Remodeling
Czasopismo naukowe
Tytuł :
Baicalin attenuates angiotensin II-induced blood pressure elevation and modulates MLCK/p-MLC signaling pathway.
Autorzy :
Liu H; Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350122, China; Fujian Key Laboratory of Integrative Medicine on Geriatrics, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350122, China; Chen Keji Academic Thought Inheritance Studio, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350122, China.
Cheng Y; Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350122, China; Fujian Key Laboratory of Integrative Medicine on Geriatrics, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350122, China.
Chu J; Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350122, China; Fujian Key Laboratory of Integrative Medicine on Geriatrics, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350122, China; Chen Keji Academic Thought Inheritance Studio, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350122, China.
Wu M; Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350122, China; Fujian Key Laboratory of Integrative Medicine on Geriatrics, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350122, China; Chen Keji Academic Thought Inheritance Studio, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350122, China.
Yan M; Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350122, China; Fujian Key Laboratory of Integrative Medicine on Geriatrics, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350122, China; Chen Keji Academic Thought Inheritance Studio, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350122, China.
Wang D; Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350122, China; Fujian Key Laboratory of Integrative Medicine on Geriatrics, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350122, China; Chen Keji Academic Thought Inheritance Studio, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350122, China.
Xie Q; Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350122, China; Fujian Key Laboratory of Integrative Medicine on Geriatrics, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350122, China; Chen Keji Academic Thought Inheritance Studio, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350122, China.
Ali F; Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350122, China; Fujian Key Laboratory of Integrative Medicine on Geriatrics, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350122, China; Chen Keji Academic Thought Inheritance Studio, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350122, China.
Fang Y; Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350122, China; Fujian Key Laboratory of Integrative Medicine on Geriatrics, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350122, China; Chen Keji Academic Thought Inheritance Studio, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350122, China.
Wei L; Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350122, China; Fujian Key Laboratory of Integrative Medicine on Geriatrics, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350122, China; Chen Keji Academic Thought Inheritance Studio, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350122, China.
Yang Y; Laboratory Animal Center, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350122, China.
Shen A; Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350122, China; Fujian Key Laboratory of Integrative Medicine on Geriatrics, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350122, China; Chen Keji Academic Thought Inheritance Studio, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350122, China. Electronic address: .
Peng J; Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350122, China; Fujian Key Laboratory of Integrative Medicine on Geriatrics, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350122, China; Chen Keji Academic Thought Inheritance Studio, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350122, China. Electronic address: .
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Źródło :
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2021 Nov; Vol. 143, pp. 112124. Date of Electronic Publication: 2021 Sep 04.
Typ publikacji :
Journal Article
MeSH Terms :
Aorta, Abdominal/*drug effects
Blood Pressure/*drug effects
Flavonoids/*pharmacology
Hypertension/*prevention & control
Hypoglycemic Agents/*pharmacology
Muscle, Smooth, Vascular/*drug effects
Myosin Light Chains/*metabolism
Myosin-Light-Chain Kinase/*metabolism
Angiotensin II ; Animals ; Aorta, Abdominal/enzymology ; Aorta, Abdominal/physiopathology ; Calcium Signaling/drug effects ; Cell Proliferation/drug effects ; Cells, Cultured ; Disease Models, Animal ; Hypertension/chemically induced ; Hypertension/enzymology ; Hypertension/physiopathology ; Male ; Mice, Inbred C57BL ; Muscle, Smooth, Vascular/enzymology ; Muscle, Smooth, Vascular/physiopathology ; Myocytes, Smooth Muscle/drug effects ; Myocytes, Smooth Muscle/enzymology ; Phosphorylation ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Investigation into the role of Stmn2 in vascular smooth muscle phenotype transformation during vascular injury via RNA sequencing and experimental validation.
Autorzy :
Ke X; Department of Cardiology, Fuwai Hospital, Chinese Academy of Medical Sciences, Shenzhen, (Shenzhen Sun Yat-sen Cardiovascular Hospital), Shenzhen, China.; Shenzhen University School of Medicine & Shenzhen University Health Science Center, Shenzhen, China.
Guo W; Department of Cardiology, Fuwai Hospital, Chinese Academy of Medical Sciences, Shenzhen, (Shenzhen Sun Yat-sen Cardiovascular Hospital), Shenzhen, China.
Peng Y; Department of Cardiology, Fuwai Hospital, Chinese Academy of Medical Sciences, Shenzhen, (Shenzhen Sun Yat-sen Cardiovascular Hospital), Shenzhen, China.
Feng Z; Department of Cardiology, Fuwai Hospital, Chinese Academy of Medical Sciences, Shenzhen, (Shenzhen Sun Yat-sen Cardiovascular Hospital), Shenzhen, China.
Huang YT; Department of Cardiology, Fuwai Hospital, Chinese Academy of Medical Sciences, Shenzhen, (Shenzhen Sun Yat-sen Cardiovascular Hospital), Shenzhen, China.
Deng M; Department of Cardiology, Fuwai Hospital, Chinese Academy of Medical Sciences, Shenzhen, (Shenzhen Sun Yat-sen Cardiovascular Hospital), Shenzhen, China.
Wei MX; Cardiac Surgery Department, The University of Hong Kong-Shenzhen Hospital, Shenzhen, China. .
Wang ZX; Cardiac Surgery Department, The University of Hong Kong-Shenzhen Hospital, Shenzhen, China. .
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Źródło :
Environmental science and pollution research international [Environ Sci Pollut Res Int] 2022 Jan; Vol. 29 (3), pp. 3498-3509. Date of Electronic Publication: 2021 Aug 13.
Typ publikacji :
Journal Article
MeSH Terms :
Muscle, Smooth, Vascular*
Vascular System Injuries*/genetics
Animals ; Cell Movement ; Cell Proliferation ; Cells, Cultured ; Phenotype ; Rats ; Sequence Analysis, RNA
Czasopismo naukowe
Tytuł :
Methods for Differentiating hiPSCs into Vascular Smooth Muscle Cells.
Autorzy :
Li ML; Biological and Biomedical Sciences Program, Yale University, New Haven, CT, USA.
Luo J; Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA.; Yale Stem Cell Center, New Haven, CT, USA.
Ellis MW; Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA.; Yale Stem Cell Center, New Haven, CT, USA.; Department of Cellular and Molecular Physiology, Yale University, New Haven, CT, USA.
Riaz M; Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA.
Ajaj Y; Biological and Biomedical Sciences Program, Yale University, New Haven, CT, USA.
Qyang Y; Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA. .; Yale Stem Cell Center, New Haven, CT, USA. .; Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT, USA. .; Department of Pathology, Yale School of Medicine, New Haven, CT, USA. .
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Źródło :
Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2022; Vol. 2375, pp. 21-34.
Typ publikacji :
Journal Article
MeSH Terms :
Induced Pluripotent Stem Cells*
Muscle, Smooth, Vascular*
Cell Differentiation ; Humans ; Myocytes, Smooth Muscle ; Tissue Engineering
Czasopismo naukowe
Tytuł :
GATA2 promotes human vascular smooth muscle cell proliferation via mitofusin2-mediated Ras/Raf/MEK/ERK signaling pathway.
Autorzy :
Wang Z; Beijing Anzhen Hospital, Capital Medical University, Beijing, China; Beijing Institute of Heart, Lung, Blood Vessel Diseases, Beijing, China. Electronic address: .
Wang H; Beijing Anzhen Hospital, Capital Medical University, Beijing, China; Beijing Institute of Heart, Lung, Blood Vessel Diseases, Beijing, China.
Wu Q; Beijing Anzhen Hospital, Capital Medical University, Beijing, China; Beijing Institute of Heart, Lung, Blood Vessel Diseases, Beijing, China.
Chen Y; Beijing Anzhen Hospital, Capital Medical University, Beijing, China; Beijing Institute of Heart, Lung, Blood Vessel Diseases, Beijing, China.
Liu J; Beijing Anzhen Hospital, Capital Medical University, Beijing, China; Beijing Institute of Heart, Lung, Blood Vessel Diseases, Beijing, China.
Liu Y; Beijing Anzhen Hospital, Capital Medical University, Beijing, China; Beijing Institute of Heart, Lung, Blood Vessel Diseases, Beijing, China.
Sun D; Beijing Anzhen Hospital, Capital Medical University, Beijing, China; Beijing Institute of Heart, Lung, Blood Vessel Diseases, Beijing, China.
Chen W; Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
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Źródło :
International journal of cardiology [Int J Cardiol] 2022 Jan 01; Vol. 346, pp. 62-70. Date of Electronic Publication: 2021 Nov 11.
Typ publikacji :
Journal Article
MeSH Terms :
MAP Kinase Signaling System*
Muscle, Smooth, Vascular*/metabolism
Cell Proliferation ; Extracellular Signal-Regulated MAP Kinases/metabolism ; GATA2 Transcription Factor ; Humans ; Mitogen-Activated Protein Kinase Kinases/metabolism ; Signal Transduction ; raf Kinases/metabolism
Czasopismo naukowe
Tytuł :
Correlation between nongenomic action of C19-steroids and COVID-19 severity.
Autorzy :
Perusqía M; Department of Cell Biology and Physiology, Institute for Biomedical Research, National Autonomous University of Mexico, Mexico City, Mexico. .
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Źródło :
Physiological research [Physiol Res] 2021 Dec 14; Vol. 70 (S2), pp. S135-S144.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Patient Acuity*
Aging/*blood
Androgens/*blood
COVID-19/*blood
COVID-19/*diagnosis
Muscle, Smooth, Vascular/*metabolism
Aging/pathology ; Animals ; COVID-19/physiopathology ; Female ; Humans ; Male ; Muscle, Smooth, Vascular/pathology ; Vasodilation/physiology
Czasopismo naukowe
Tytuł :
CFTR in the regulation of pulmonary vascular tone and remodeling.
Autorzy :
Tabeling C; Division of Pulmonary Inflammation, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.; Dept of Infectious Diseases and Respiratory Medicine, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.; Berlin Institute of Health, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Witzenrath M; Division of Pulmonary Inflammation, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.; Dept of Infectious Diseases and Respiratory Medicine, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.; German Center for Lung Research (DZL), Partner Site Charité, Berlin, Germany.
Kuebler WM; German Center for Lung Research (DZL), Partner Site Charité, Berlin, Germany .; Institute of Physiology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.; German Center for Cardiovascular Research (DZHK), Partner Site Berlin, Berlin, Germany.; Keenan Research Centre for Biomedical Science, St. Michael's Hospital, Toronto, ON, Canada.; Depts of Physiology and Surgery, University of Toronto, Toronto, ON, Canada.
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Źródło :
The European respiratory journal [Eur Respir J] 2021 Dec 09; Vol. 58 (6). Date of Electronic Publication: 2021 Dec 09 (Print Publication: 2021).
Typ publikacji :
Letter; Research Support, Non-U.S. Gov't; Comment
MeSH Terms :
Cystic Fibrosis Transmembrane Conductance Regulator*/genetics
Muscle, Smooth, Vascular*
Humans ; Vasoconstriction
Raport
Tytuł :
FAK Activation Promotes SMC Dedifferentiation via Increased DNA Methylation in Contractile Genes.
Autorzy :
Jeong K; Departments of Biochemistry and Molecular Biology (K.J., J.M.M., J.-H.K., H.P., Y.A.R.R., J.-S.K., R.E.H., S.-T.S.L.), University of South Alabama, College of Medicine, Mobile.
Murphy JM; Departments of Biochemistry and Molecular Biology (K.J., J.M.M., J.-H.K., H.P., Y.A.R.R., J.-S.K., R.E.H., S.-T.S.L.), University of South Alabama, College of Medicine, Mobile.
Kim JH; Departments of Biochemistry and Molecular Biology (K.J., J.M.M., J.-H.K., H.P., Y.A.R.R., J.-S.K., R.E.H., S.-T.S.L.), University of South Alabama, College of Medicine, Mobile.
Campbell PM; Pathology (P.M.C.), University of South Alabama, College of Medicine, Mobile.
Park H; Departments of Biochemistry and Molecular Biology (K.J., J.M.M., J.-H.K., H.P., Y.A.R.R., J.-S.K., R.E.H., S.-T.S.L.), University of South Alabama, College of Medicine, Mobile.
Rodriguez YAR; Departments of Biochemistry and Molecular Biology (K.J., J.M.M., J.-H.K., H.P., Y.A.R.R., J.-S.K., R.E.H., S.-T.S.L.), University of South Alabama, College of Medicine, Mobile.
Choi CS; Physiology and Cell Biology (C.-S.C., D.S.W.), University of South Alabama, College of Medicine, Mobile.
Kim JS; Departments of Biochemistry and Molecular Biology (K.J., J.M.M., J.-H.K., H.P., Y.A.R.R., J.-S.K., R.E.H., S.-T.S.L.), University of South Alabama, College of Medicine, Mobile.; Now with: Department of Biotechnology, Korea National Transportation University, Chungbuk, Korea (J.-S.K.).
Park S; Departments of Pharmacology and Convergence Medical Sciences (S.P.), Institute of Health Sciences, Gyeongsang National University, School of Medicine, Jinju, Korea.
Kim HJ; Anatomy and Convergence Medical Sciences (H.J.K.), Institute of Health Sciences, Gyeongsang National University, School of Medicine, Jinju, Korea.
Scammell JG; Comparative Medicine (J.G.S.), University of South Alabama, College of Medicine, Mobile.
Weber DS; Physiology and Cell Biology (C.-S.C., D.S.W.), University of South Alabama, College of Medicine, Mobile.
Honkanen RE; Departments of Biochemistry and Molecular Biology (K.J., J.M.M., J.-H.K., H.P., Y.A.R.R., J.-S.K., R.E.H., S.-T.S.L.), University of South Alabama, College of Medicine, Mobile.
Schlaepfer DD; Department of Reproductive Medicine, Moores Cancer Center, University of California, San Diego, La Jolla (D.D.S.).
Ahn EE; Department of Pathology, O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham (E.-Y.E.A.).
Lim SS; Departments of Biochemistry and Molecular Biology (K.J., J.M.M., J.-H.K., H.P., Y.A.R.R., J.-S.K., R.E.H., S.-T.S.L.), University of South Alabama, College of Medicine, Mobile.
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Źródło :
Circulation research [Circ Res] 2021 Dec 03; Vol. 129 (12), pp. e215-e233. Date of Electronic Publication: 2021 Oct 27.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Dedifferentiation*
DNA Methylation*
Contractile Proteins/*genetics
Focal Adhesion Kinase 1/*metabolism
Muscle, Smooth, Vascular/*metabolism
Myocytes, Smooth Muscle/*metabolism
Animals ; Cells, Cultured ; Contractile Proteins/metabolism ; DNA Methyltransferase 3A/genetics ; DNA Methyltransferase 3A/metabolism ; Focal Adhesion Kinase 1/genetics ; Intracellular Signaling Peptides and Proteins/genetics ; Intracellular Signaling Peptides and Proteins/metabolism ; Mice ; Mice, Inbred C57BL ; Muscle, Smooth, Vascular/cytology ; Myocytes, Smooth Muscle/cytology ; Myocytes, Smooth Muscle/physiology ; Proteolysis ; Ubiquitination ; Up-Regulation
Czasopismo naukowe
Tytuł :
CircSOD2: A Novel Regulator for Smooth Muscle Proliferation and Neointima Formation.
Autorzy :
Mei X; Departments of Surgery (X.M., X.-B.C., S.-Y.C.), University of Missouri School of Medicine, Columbia.; Department of Physiology and Pharmacology (X.M., S.-Y.C.), University of Georgia, Athens.
Cui XB; Departments of Surgery (X.M., X.-B.C., S.-Y.C.), University of Missouri School of Medicine, Columbia.
Li Y; Institute of Bioinformatics (Y.L.), University of Georgia, Athens.
Chen SY; Departments of Surgery (X.M., X.-B.C., S.-Y.C.), University of Missouri School of Medicine, Columbia.; Medical Pharmacology and Physiology (S.-Y.C.), University of Missouri School of Medicine, Columbia.; Department of Physiology and Pharmacology (X.M., S.-Y.C.), University of Georgia, Athens.
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Źródło :
Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2021 Dec; Vol. 41 (12), pp. 2961-2973. Date of Electronic Publication: 2021 Oct 21.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Carotid Artery Injuries/*genetics
Muscle, Smooth, Vascular/*metabolism
Neointima/*genetics
Superoxide Dismutase/*genetics
Vascular Remodeling/*genetics
Animals ; Carotid Artery Injuries/metabolism ; Carotid Artery Injuries/pathology ; Cell Movement ; Cell Proliferation ; Cells, Cultured ; Disease Models, Animal ; Male ; Muscle, Smooth, Vascular/pathology ; Neointima/metabolism ; Rats ; Rats, Sprague-Dawley ; Signal Transduction ; Superoxide Dismutase/biosynthesis
Czasopismo naukowe
Tytuł :
Vascular calcium signalling and ageing.
Autorzy :
Harraz OF; Department of Pharmacology, Larner College of Medicine, University of Vermont, Burlington, Vermont, USA.; Vermont Center for Cardiovascular and Brain Health, University of Vermont, Burlington, Vermont, USA.
Jensen LJ; Pathobiological Sciences, Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Frederiksberg C, Denmark.
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Źródło :
The Journal of physiology [J Physiol] 2021 Dec; Vol. 599 (24), pp. 5361-5377. Date of Electronic Publication: 2021 Nov 21.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Calcium*/metabolism
Muscle, Smooth, Vascular*/metabolism
Calcium Signaling ; Endothelial Cells/metabolism ; Endothelium, Vascular/metabolism
Czasopismo naukowe
Tytuł :
Paxillin controls actin stress fiber formation and migration of vascular smooth muscle cells by directly binding to the active Fyn.
Autorzy :
Zhang Y; Department of Molecular and Cellular Physiology, Graduate School of Medicine, Yamaguchi University, Ube, Japan.
Kishi H; Department of Molecular and Cellular Physiology, Graduate School of Medicine, Yamaguchi University, Ube, Japan.
Morita T; Department of Molecular and Cellular Physiology, Graduate School of Medicine, Yamaguchi University, Ube, Japan.
Kobayashi S; Department of Molecular and Cellular Physiology, Graduate School of Medicine, Yamaguchi University, Ube, Japan.; Department of Advanced Preventive Medicine, Medical School, Yamaguchi University, Ube, Japan.
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Źródło :
FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2021 Dec; Vol. 35 (12), pp. e22012.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Movement*
Actins/*metabolism
Coronary Vessels/*pathology
Muscle, Smooth, Vascular/*pathology
Paxillin/*metabolism
Proto-Oncogene Proteins c-fyn/*metabolism
Stress Fibers/*pathology
Coronary Vessels/metabolism ; Humans ; Muscle, Smooth, Vascular/metabolism ; Phosphorylation ; Stress Fibers/metabolism
Czasopismo naukowe
Tytuł :
Transforming growth factor-β1 inhibits interleukin-1β-induced expression of inflammatory genes and Cathepsin S activity in human vascular smooth muscle cells.
Autorzy :
Dhaouadi N; EA 4173 Génomique Fonctionnelle de l'Hypertension Artérielle, Université Lyon 1, Lyon, France.; Unité de Physiologie Intégrée, Laboratoire de Pathologies Vasculaires, Faculté des Sciences de Bizerte, Université de Carthage, Bizerte, Tunisia.
Nehme A; EA 4173 Génomique Fonctionnelle de l'Hypertension Artérielle, Université Lyon 1, Lyon, France.; PRASE, Lebanese University, Beirut, Lebanon.
Faour WH; Gilbert & Rose-Marie Chagoury School of Medicine, Lebanese American University, Byblos, Lebanon.
Feugier P; EA 4173 Génomique Fonctionnelle de l'Hypertension Artérielle, Université Lyon 1, Lyon, France.
Cerutti C; EA 4173 Génomique Fonctionnelle de l'Hypertension Artérielle, Université Lyon 1, Lyon, France.
Kacem K; Unité de Physiologie Intégrée, Laboratoire de Pathologies Vasculaires, Faculté des Sciences de Bizerte, Université de Carthage, Bizerte, Tunisia.
Eid AH; Biomedical and Pharmaceutical Research Unit and Department of Basic Medical Sciences, College of Medicine, QU Health, Qatar University, Doha, Qatar.
Li JY; EA 4173 Génomique Fonctionnelle de l'Hypertension Artérielle, Université Lyon 1, Lyon, France.
Zibara K; PRASE, Lebanese University, Beirut, Lebanon.; Department of Biology, Faculty of sciences - I, Lebanese University, Beirut, Lebanon.
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Źródło :
Fundamental & clinical pharmacology [Fundam Clin Pharmacol] 2021 Dec; Vol. 35 (6), pp. 979-988. Date of Electronic Publication: 2021 Mar 16.
Typ publikacji :
Journal Article
MeSH Terms :
Muscle, Smooth, Vascular*
Transforming Growth Factor beta1*
Cathepsins/genetics ; Cells, Cultured ; Humans ; Interleukin-1beta ; Transforming Growth Factor beta
Czasopismo naukowe

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