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Wyszukujesz frazę ""MutL Protein Homolog 1"" wg kryterium: Temat


Tytuł :
Lynch syndrome-associated repeated stroke with MLH1 frame-shift mutation.
Autorzy :
Zhang M; Department of Neurology, Xiangya Hospital of Central South University, Changsha, 410008, Hunan, China.
Yang H; Department of Neurology, Xiangya Hospital of Central South University, Changsha, 410008, Hunan, China.
Chen Z; Department of Neurology, Xiangya Hospital of Central South University, Changsha, 410008, Hunan, China.
Fan Y; Department of Neurology, Xiangya Hospital of Central South University, Changsha, 410008, Hunan, China.
Hu X; Department of Neurology, Xiangya Hospital of Central South University, Changsha, 410008, Hunan, China.
Liu W; Department of Neurology, Xiangya Hospital of Central South University, Changsha, 410008, Hunan, China. .
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Źródło :
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology [Neurol Sci] 2021 Apr; Vol. 42 (4), pp. 1631-1635. Date of Electronic Publication: 2021 Jan 12.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Colorectal Neoplasms, Hereditary Nonpolyposis*/complications
Colorectal Neoplasms, Hereditary Nonpolyposis*/diagnostic imaging
Colorectal Neoplasms, Hereditary Nonpolyposis*/genetics
MutL Protein Homolog 1*/genetics
Stroke*
Adult ; DNA Mismatch Repair ; Female ; Genetic Predisposition to Disease ; Humans ; Mutation
Czasopismo naukowe
Tytuł :
Protons and High-Linear Energy Transfer Radiation Induce Genetically Similar Lymphomas With High Penetrance in a Mouse Model of the Aging Human Hematopoietic System.
Autorzy :
Patel R; Department of Radiation Oncology, Duke University, Durham, North Carolina.
Zhang L; Department of Medicine, Case Western Reserve University, Cleveland, Ohio.
Desai A; Department of Medicine, Case Western Reserve University, Cleveland, Ohio; Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, Ohio.
Hoenerhoff MJ; Unit for Laboratory Animal Medicine, University of Michigan, Ann Arbor, Michigan.
Kennedy LH; Unit for Laboratory Animal Medicine, University of Michigan, Ann Arbor, Michigan.
Radivoyevitch T; Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio.
La Tessa C; University of Trento, Trento, Italy; Trento Institute for Fundamental Physics and Applications TIFPA-INFN, Trento, Italy.
Gerson SL; Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, Ohio.
Welford SM; Sylvester Comprehensive Cancer Center, University of Miami, Miami, Florida; Department of Radiation Oncology, University of Miami, Miami, Florida. Electronic address: .
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Źródło :
International journal of radiation oncology, biology, physics [Int J Radiat Oncol Biol Phys] 2020 Nov 15; Vol. 108 (4), pp. 1091-1102. Date of Electronic Publication: 2020 Jul 04.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Linear Energy Transfer*
Hematopoietic System/*radiation effects
Lymphoma/*genetics
MutL Protein Homolog 1/*deficiency
Neoplasms, Radiation-Induced/*genetics
Protons/*adverse effects
Silicon/*adverse effects
Aging ; Animals ; DNA Mismatch Repair ; Disease Models, Animal ; Female ; Gene Expression Profiling ; Hematopoietic System/physiology ; Humans ; Lymphoma/pathology ; Male ; Mice ; MutL Protein Homolog 1/genetics ; Neoplasms, Radiation-Induced/pathology ; Penetrance ; Radiation Exposure/adverse effects ; Sequence Analysis, RNA/methods ; Space Flight ; Whole-Body Irradiation/adverse effects ; Whole-Body Irradiation/methods
Czasopismo naukowe
Tytuł :
Regulation of the MLH1-MLH3 endonuclease in meiosis.
Autorzy :
Cannavo E; Institute for Research in Biomedicine, Faculty of Biomedical Sciences, Università della Svizzera italiana (USI), Bellinzona, Switzerland.
Sanchez A; Institute for Research in Biomedicine, Faculty of Biomedical Sciences, Università della Svizzera italiana (USI), Bellinzona, Switzerland.
Anand R; Institute for Research in Biomedicine, Faculty of Biomedical Sciences, Università della Svizzera italiana (USI), Bellinzona, Switzerland.
Ranjha L; Institute for Research in Biomedicine, Faculty of Biomedical Sciences, Università della Svizzera italiana (USI), Bellinzona, Switzerland.
Hugener J; Department of Biology, Institute of Biochemistry, Eidgenössische Technische Hochschule (ETH), Zürich, Switzerland.
Adam C; Institut Curie, PSL Research University, CNRS UMR3244, Paris, France.; Paris Sorbonne Université, Paris, France.
Acharya A; Institute for Research in Biomedicine, Faculty of Biomedical Sciences, Università della Svizzera italiana (USI), Bellinzona, Switzerland.; Department of Biology, Institute of Biochemistry, Eidgenössische Technische Hochschule (ETH), Zürich, Switzerland.
Weyland N; Institute of Molecular Cancer Research, University of Zürich, Zürich, Switzerland.
Aran-Guiu X; Genome Damage and Stability Centre, School of Life Sciences, University of Sussex, Brighton, UK.
Charbonnier JB; I2BC, iBiTec-S, CEA, CNRS UMR 9198, Université Paris-Sud, Gif-sur-Yvette, France.; Université Paris Sud, Orsay, France.
Hoffmann ER; Genome Damage and Stability Centre, School of Life Sciences, University of Sussex, Brighton, UK.; DNRF Center for Chromosome Stability, Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Borde V; Institut Curie, PSL Research University, CNRS UMR3244, Paris, France.; Paris Sorbonne Université, Paris, France.
Matos J; Department of Biology, Institute of Biochemistry, Eidgenössische Technische Hochschule (ETH), Zürich, Switzerland.
Cejka P; Institute for Research in Biomedicine, Faculty of Biomedical Sciences, Università della Svizzera italiana (USI), Bellinzona, Switzerland. .; Department of Biology, Institute of Biochemistry, Eidgenössische Technische Hochschule (ETH), Zürich, Switzerland. .
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Źródło :
Nature [Nature] 2020 Oct; Vol. 586 (7830), pp. 618-622. Date of Electronic Publication: 2020 Aug 19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Crossing Over, Genetic*
Meiosis*
Endonucleases/*metabolism
MutL Protein Homolog 1/*metabolism
MutL Proteins/*metabolism
Amino Acid Motifs ; Amino Acid Sequence ; Cell Cycle Proteins/metabolism ; Chromosomes, Human/genetics ; Conserved Sequence ; DNA/metabolism ; DNA Cleavage ; DNA Repair Enzymes/metabolism ; DNA, Cruciform/metabolism ; Exodeoxyribonucleases/metabolism ; Humans ; MutL Protein Homolog 1/chemistry ; MutL Proteins/chemistry ; MutS Proteins/metabolism ; Proliferating Cell Nuclear Antigen/metabolism ; Replication Protein C/metabolism
Czasopismo naukowe
Tytuł :
DNMT1 promotes cell proliferation via methylating hMLH1 and hMSH2 promoters in EGFR-mutated non-small cell lung cancer.
Autorzy :
Wu XY; Department of Respiration, Jinhua Guangfu Cancer Hospital, No. 1296, North Huancheng Rd, Wucheng District, Jinhua, Zhejiang 321000, China.
Chen HC; Department of Respiration, Jinhua Guangfu Cancer Hospital, No. 1296, North Huancheng Rd, Wucheng District, Jinhua, Zhejiang 321000, China.
Li WW; Department of Respiration, Jinhua Guangfu Cancer Hospital, No. 1296, North Huancheng Rd, Wucheng District, Jinhua, Zhejiang 321000, China.
Yan JD; Department of Respiration, Jinhua Guangfu Cancer Hospital, No. 1296, North Huancheng Rd, Wucheng District, Jinhua, Zhejiang 321000, China.
Lv RY; Department of Respiration, Jinhua Guangfu Cancer Hospital, No. 1296, North Huancheng Rd, Wucheng District, Jinhua, Zhejiang 321000, China.
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Źródło :
Journal of biochemistry [J Biochem] 2020 Aug 01; Vol. 168 (2), pp. 151-157.
Typ publikacji :
Journal Article
MeSH Terms :
DNA Methylation*
Promoter Regions, Genetic*
Carcinoma, Non-Small-Cell Lung/*genetics
DNA (Cytosine-5-)-Methyltransferase 1/*metabolism
Lung Neoplasms/*genetics
MutL Protein Homolog 1/*genetics
MutS Homolog 2 Protein/*genetics
A549 Cells ; Carcinoma, Non-Small-Cell Lung/metabolism ; Carcinoma, Non-Small-Cell Lung/pathology ; Cell Proliferation ; ErbB Receptors/genetics ; ErbB Receptors/metabolism ; Female ; Humans ; Lung Neoplasms/metabolism ; Lung Neoplasms/pathology ; Male ; Middle Aged ; MutL Protein Homolog 1/metabolism ; MutS Homolog 2 Protein/metabolism ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł :
[Analysis of microsatellite instability in endometroid carcinoma with deficient mismatch repair].
Autorzy :
Zhang YH; Department of Pathology, Peking Union Medical College Hospital, Chinese Academy of Medical Science, Peking Union Medical College, Beijing 100730, China.
Wu HW; Department of Pathology, Peking Union Medical College Hospital, Chinese Academy of Medical Science, Peking Union Medical College, Beijing 100730, China.
Wang J; Department of Pathology, Peking Union Medical College Hospital, Chinese Academy of Medical Science, Peking Union Medical College, Beijing 100730, China.
Liang ZY; Department of Pathology, Peking Union Medical College Hospital, Chinese Academy of Medical Science, Peking Union Medical College, Beijing 100730, China.
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Źródło :
Zhonghua bing li xue za zhi = Chinese journal of pathology [Zhonghua Bing Li Xue Za Zhi] 2021 May 08; Vol. 50 (5), pp. 470-475.
Typ publikacji :
Journal Article
MeSH Terms :
Carcinoma, Endometrioid*
Microsatellite Instability*
DNA Mismatch Repair/genetics ; Female ; Humans ; Immunohistochemistry ; Mismatch Repair Endonuclease PMS2/genetics ; Mismatch Repair Endonuclease PMS2/metabolism ; MutL Protein Homolog 1/genetics ; MutL Protein Homolog 1/metabolism ; MutS Homolog 2 Protein/genetics ; MutS Homolog 2 Protein/metabolism
Czasopismo naukowe
Tytuł :
[Mismatch repair protein expression of colorectal cancer: a retrospective analysis of 3 428 cases].
Autorzy :
Liu Y; Department of Pathology, Tianjin Medical University Cancer Institute and Hospital; National Clinical Research Center for Cancer; Key Laboratory of Cancer Prevention and Therapy, Tianjin;Tianjin's Clinical Research Center for Cancer, Tianjin 300060, China.
Guo YH; Department of Pathology, Tianjin Medical University Cancer Institute and Hospital; National Clinical Research Center for Cancer; Key Laboratory of Cancer Prevention and Therapy, Tianjin;Tianjin's Clinical Research Center for Cancer, Tianjin 300060, China.
Luo Y; Department of Pathology, Tianjin Medical University Cancer Institute and Hospital; National Clinical Research Center for Cancer; Key Laboratory of Cancer Prevention and Therapy, Tianjin;Tianjin's Clinical Research Center for Cancer, Tianjin 300060, China.
Sun L; Department of Pathology, Tianjin Medical University Cancer Institute and Hospital; National Clinical Research Center for Cancer; Key Laboratory of Cancer Prevention and Therapy, Tianjin;Tianjin's Clinical Research Center for Cancer, Tianjin 300060, China.
Zhao S; Department of Pathology, Tianjin Medical University Cancer Institute and Hospital; National Clinical Research Center for Cancer; Key Laboratory of Cancer Prevention and Therapy, Tianjin;Tianjin's Clinical Research Center for Cancer, Tianjin 300060, China.
Shao B; Department of Pathology, Tianjin Medical University Cancer Institute and Hospital; National Clinical Research Center for Cancer; Key Laboratory of Cancer Prevention and Therapy, Tianjin;Tianjin's Clinical Research Center for Cancer, Tianjin 300060, China.
Zang FL; Department of Pathology, Tianjin Medical University Cancer Institute and Hospital; National Clinical Research Center for Cancer; Key Laboratory of Cancer Prevention and Therapy, Tianjin;Tianjin's Clinical Research Center for Cancer, Tianjin 300060, China.
Qiu ZQ; Department of Pathology, Tianjin Medical University Cancer Institute and Hospital; National Clinical Research Center for Cancer; Key Laboratory of Cancer Prevention and Therapy, Tianjin;Tianjin's Clinical Research Center for Cancer, Tianjin 300060, China.
Sun BC; Department of Pathology, Tianjin Medical University Cancer Institute and Hospital; National Clinical Research Center for Cancer; Key Laboratory of Cancer Prevention and Therapy, Tianjin;Tianjin's Clinical Research Center for Cancer, Tianjin 300060, China.
Sun Y; Department of Pathology, Tianjin Medical University Cancer Institute and Hospital; National Clinical Research Center for Cancer; Key Laboratory of Cancer Prevention and Therapy, Tianjin;Tianjin's Clinical Research Center for Cancer, Tianjin 300060, China.
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Źródło :
Zhonghua bing li xue za zhi = Chinese journal of pathology [Zhonghua Bing Li Xue Za Zhi] 2021 Apr 08; Vol. 50 (4), pp. 369-375.
Typ publikacji :
Journal Article
MeSH Terms :
Colorectal Neoplasms*/genetics
DNA Mismatch Repair*/genetics
DNA-Binding Proteins/genetics ; DNA-Binding Proteins/metabolism ; Female ; Humans ; Microsatellite Instability ; Middle Aged ; Mismatch Repair Endonuclease PMS2/genetics ; Mismatch Repair Endonuclease PMS2/metabolism ; MutL Protein Homolog 1/genetics ; MutL Protein Homolog 1/metabolism ; MutS Homolog 2 Protein/metabolism ; Retrospective Studies
Czasopismo naukowe
Tytuł :
[Immunohistochemical double staining of CK8/18 and MLH1 or PMS2 in detecting the expression of mismatch repair protein in solid tumors].
Autorzy :
Liu Y; Department of Pathology, Tianjin Medical University Cancer Institute and Hospital; National Clinical Research Center for Cancer; Key Laboratory of Cancer Prevention and Therapy,Tianjin; Tianjin's Clinical Research Center for Cancer, Tianjin 300060, China.
Guo YH; Department of Pathology, Tianjin Medical University Cancer Institute and Hospital; National Clinical Research Center for Cancer; Key Laboratory of Cancer Prevention and Therapy,Tianjin; Tianjin's Clinical Research Center for Cancer, Tianjin 300060, China.
Wu SL; Department of Pathology, Tianjin Medical University Cancer Institute and Hospital; National Clinical Research Center for Cancer; Key Laboratory of Cancer Prevention and Therapy,Tianjin; Tianjin's Clinical Research Center for Cancer, Tianjin 300060, China.
Yue YW; Department of Pathology, Tianjin Medical University Cancer Institute and Hospital; National Clinical Research Center for Cancer; Key Laboratory of Cancer Prevention and Therapy,Tianjin; Tianjin's Clinical Research Center for Cancer, Tianjin 300060, China.
Sun Y; Department of Pathology, Tianjin Medical University Cancer Institute and Hospital; National Clinical Research Center for Cancer; Key Laboratory of Cancer Prevention and Therapy,Tianjin; Tianjin's Clinical Research Center for Cancer, Tianjin 300060, China.
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Źródło :
Zhonghua bing li xue za zhi = Chinese journal of pathology [Zhonghua Bing Li Xue Za Zhi] 2021 May 08; Vol. 50 (5), pp. 520-523.
Typ publikacji :
Journal Article
MeSH Terms :
DNA Mismatch Repair*
Neoplasms*
DNA Repair Enzymes/genetics ; Humans ; Mismatch Repair Endonuclease PMS2/genetics ; Mismatch Repair Endonuclease PMS2/metabolism ; MutL Protein Homolog 1/genetics ; MutS Homolog 2 Protein/genetics ; MutS Homolog 2 Protein/metabolism ; Staining and Labeling
Czasopismo naukowe
Tytuł :
Human MutLγ, the MLH1-MLH3 heterodimer, is an endonuclease that promotes DNA expansion.
Autorzy :
Kadyrova LY; Department of Biochemistry and Molecular Biology, Southern Illinois University School of Medicine, Carbondale, IL 62901.
Gujar V; Department of Biochemistry and Molecular Biology, Southern Illinois University School of Medicine, Carbondale, IL 62901.
Burdett V; Department of Biochemistry, Duke University Medical Center, Durham, NC 27710.
Modrich PL; Department of Biochemistry, Duke University Medical Center, Durham, NC 27710; .; Howard Hughes Medical Institute, Duke University Medical Center, Durham, NC 27710.
Kadyrov FA; Department of Biochemistry and Molecular Biology, Southern Illinois University School of Medicine, Carbondale, IL 62901; .
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Feb 18; Vol. 117 (7), pp. 3535-3542. Date of Electronic Publication: 2020 Feb 03.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
MutL Protein Homolog 1/*metabolism
MutL Proteins/*metabolism
DNA Mismatch Repair ; Dimerization ; Endonucleases/chemistry ; Endonucleases/genetics ; Endonucleases/metabolism ; Humans ; MutL Protein Homolog 1/chemistry ; MutL Protein Homolog 1/genetics ; MutL Proteins/chemistry ; MutL Proteins/genetics ; Trinucleotide Repeat Expansion
Czasopismo naukowe
Tytuł :
Extracellular vesicles transmitted miR-31-5p promotes sorafenib resistance by targeting MLH1 in renal cell carcinoma.
Autorzy :
He J; Department of Biotherapy, Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China.; Department of Head and Neck Cancer, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
He J; State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Min L; Department of Orthopedics, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
He Y; Department of Biotherapy, Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Guan H; Department of Biotherapy, Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Wang J; Department of Biotherapy, Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Peng X; Department of Biotherapy, Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
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Źródło :
International journal of cancer [Int J Cancer] 2020 Feb 15; Vol. 146 (4), pp. 1052-1063. Date of Electronic Publication: 2019 Jul 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Carcinoma, Renal Cell/*drug therapy
Extracellular Vesicles/*metabolism
MicroRNAs/*metabolism
MutL Protein Homolog 1/*metabolism
Sorafenib/*pharmacology
Animals ; Antineoplastic Agents/pharmacology ; Carcinoma, Renal Cell/genetics ; Carcinoma, Renal Cell/metabolism ; Extracellular Vesicles/genetics ; Humans ; Kidney Neoplasms/drug therapy ; Kidney Neoplasms/genetics ; Kidney Neoplasms/metabolism ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; MutL Protein Homolog 1/biosynthesis ; MutL Protein Homolog 1/genetics ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
Correlation of MLH1 polymorphisms, survival statistics, in silico assessment and gene downregulation with clinical outcomes among breast cancer cases.
Autorzy :
Malik SS; Fatima Jinnah Women University, The Mall Rawalpindi, Rawalpindi, Pakistan. .; Armed Forces Institute of Pathology, Rawalpindi, Pakistan. .
Zia A; National Centre for Bioinformatics, Quaid-i-Azam University, Islamabad, Pakistan.
Mubarik S; Department of Epidemiology and Biostatistics, School of Health Sciences, Wuhan University, Wuhan, China.
Masood N; Fatima Jinnah Women University, The Mall Rawalpindi, Rawalpindi, Pakistan.
Rashid S; National Centre for Bioinformatics, Quaid-i-Azam University, Islamabad, Pakistan.
Sherrard A; Department of Cellular and Molecular Medicine, School of Life Sciences, Bristol University, Bristol, UK.
Khan MB; Armed Forces Institute of Pathology, Rawalpindi, Pakistan.
Khadim MT; Armed Forces Institute of Pathology, Rawalpindi, Pakistan.
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Źródło :
Molecular biology reports [Mol Biol Rep] 2020 Jan; Vol. 47 (1), pp. 683-692. Date of Electronic Publication: 2019 Nov 08.
Typ publikacji :
Journal Article
MeSH Terms :
Breast Neoplasms*/chemistry
Breast Neoplasms*/genetics
Breast Neoplasms*/mortality
MutL Protein Homolog 1*/analysis
MutL Protein Homolog 1*/chemistry
MutL Protein Homolog 1*/genetics
MutL Protein Homolog 1*/metabolism
Adult ; Breast/chemistry ; DNA Mutational Analysis ; Down-Regulation/genetics ; Female ; Humans ; Middle Aged ; Polymorphism, Single Nucleotide/genetics
Czasopismo naukowe
Tytuł :
Prognostic Role of Mismatch Repair Status, Histotype and High-Risk Pathologic Features in Stage II Small Bowel Adenocarcinomas.
Autorzy :
Vanoli A; Anatomic Pathology Unit, Department of Molecular Medicine, University of Pavia and Fondazione IRCCS San Matteo Hospital, Pavia, Italy. .
Grillo F; Pathology Unit, Department of Surgical and Diagnostic Sciences, University of Genoa and Ospedale Policlinico San Martino University Hospital, Genoa, Italy.
Guerini C; Anatomic Pathology Unit, Department of Molecular Medicine, University of Pavia and Fondazione IRCCS San Matteo Hospital, Pavia, Italy.
Neri G; Anatomic Pathology Unit, Department of Molecular Medicine, University of Pavia and Fondazione IRCCS San Matteo Hospital, Pavia, Italy.
Arpa G; Anatomic Pathology Unit, Department of Molecular Medicine, University of Pavia and Fondazione IRCCS San Matteo Hospital, Pavia, Italy.
Klersy C; Clinical Epidemiology and Biometry Unit, Fondazione IRCCS San Matteo Hospital, Pavia, Italy.
Nesi G; Division of Pathological Anatomy, Department of Surgery and Translational Medicine, University of Florence, Florence, Italy.
Giuffrida P; Department of Internal Medicine, University of Pavia and Fondazione IRCCS San Matteo Hospital, Pavia, Italy.
Sampietro G; Unit of General Surgery, ASST Rhodense, Rho Hospital, University of Milan, Milan, Italy.
Ardizzone S; Gastroenterology Unit, Luigi Sacco University Hospital, Milan, Italy.
Fociani P; Anatomic Pathology Unit, ASST Ovest Milanese, Milan, Italy.
Fiocca R; Pathology Unit, Department of Surgical and Diagnostic Sciences, University of Genoa and Ospedale Policlinico San Martino University Hospital, Genoa, Italy.
Latella G; Gastroenterology Unit, Department of Life and Environmental Sciences, University of L'Aquila, L'Aquila, Italy.
Sessa F; Pathology Unit, Department of Medicine and Surgery, University of Insubria, Varese, Italy.
D'Errico A; Department of Experimental, Diagnostic and Specialty Medicine (DIMES), Institute of Oncology and Transplant Pathology, St. Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy.
Malvi D; Department of Experimental, Diagnostic and Specialty Medicine (DIMES), Institute of Oncology and Transplant Pathology, St. Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy.
Mescoli C; Pathology Unit, Department of Medicine, University of Padua, Padua, Italy.
Rugge M; Pathology Unit, Department of Medicine, University of Padua, Padua, Italy.
Ferrero S; Division of Pathology, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Department of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Italy.
Poggioli G; Surgery of the Alimentary Tract, Department of Medical and Surgical Sciences, Sant'Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy.
Rizzello F; Intestinal Chronic Bowel Disease Unit, Department of Medical and Surgical Sciences, Sant'Orsola-Malpighi Hospital, Alma Mater Studiorum University of Bologna, Bologna, Italy.
Macciomei MC; Pathology Unit, San Camillo-Forlanini Hospital, Rome, Italy.
Santini D; Department of Experimental, Diagnostic and Specialty Medicine (DIMES), Institute of Oncology and Transplant Pathology, St. Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy.
Volta U; Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.
De Giorgio R; Department of Morphology, Surgery and Experimental Medicine, University of Ferrara, Ferrara, Italy.
Caio G; Department of Morphology, Surgery and Experimental Medicine, University of Ferrara, Ferrara, Italy.
Calabrò A; Department of Experimental and Clinical Biomedical Sciences, University of Florence, Florence, Italy.
Ciacci C; Department of Medicine and Surgery, University of Salerno, Salerno, Italy.
D'Armiento M; Public Health Department, Federico II University of Naples, Naples, Italy.
Rizzo A; Unit of Pathology, Cervello Hospital, Palermo, Italy.
Solina G; Units of General Surgery, Cervello Hospital, Palermo, Italy.
Martino M; Department of Internal Medicine, University of Pavia and Fondazione IRCCS San Matteo Hospital, Pavia, Italy.
Tonelli F; Surgery and Translational Medicine, University of Florence, Florence, Italy.
Villanacci V; Institute of Pathology, Spedali Civili Hospital, Brescia, Italy.
Cannizzaro R; Department of Gastroenterology, Centro di Riferimento Oncologico (CRO) di Aviano IRCCS, Aviano, Italy.
Canzonieri V; Pathology Unit, Centro di Riferimento Oncologico (CRO) di Aviano IRCCS, Aviano, Italy.; Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy.
Florena AM; Pathologic Anatomy Unit, Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, University of Palermo, Palermo, Italy.
Biancone L; Department of Systems Medicine, University of Tor Vergata, Rome, Italy.
Monteleone G; Department of Systems Medicine, University of Tor Vergata, Rome, Italy.
Caronna R; Department of Surgical Sciences, La Sapienza University, Rome, Italy.
Ciardi A; Department of Radiological, Oncological, Pathological Sciences, Umberto I Hospital, La Sapienza University, Rome, Italy.
Elli L; Gastroenterology and Endoscopy Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Caprioli F; Gastroenterology and Endoscopy Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Vecchi M; Gastroenterology and Endoscopy Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
D'Incà R; Gastroenterology Section, Department of Surgery, Oncology and Gastroenterology, University of Padua, Padua, Italy.
Zingone F; Gastroenterology Section, Department of Surgery, Oncology and Gastroenterology, University of Padua, Padua, Italy.
D'Odorico A; Gastroenterology Section, Department of Surgery, Oncology and Gastroenterology, University of Padua, Padua, Italy.
Lenti MV; Department of Internal Medicine, University of Pavia and Fondazione IRCCS San Matteo Hospital, Pavia, Italy.
Oreggia B; General Surgery Unit, Ca' Granda-Ospedale Maggiore Policlinico, Milan, Italy.
Reggiani Bonetti L; Section of Pathology, Department of Diagnostic Medicine and Public Health, University of Modena and Reggio Emilia, Modena, Italy.
Giannone AG; Pathologic Anatomy Unit, Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, University of Palermo, Palermo, Italy.
Orlandi A; Department of Biopathology and Image Diagnostics, University of Tor Vergata, Rome, Italy.
Barresi V; Section of Anatomical Pathology, Department of Diagnostics and Public Health, University and Hospital Trust of Verona, Verona, Italy.
Ciccocioppo R; Gastroenterology Unit, Department of Medicine, AOUI Policlinico G.B. Rossi, University of Verona, Verona, Italy.
Amodeo G; Gastroenterology Unit, Department of Medicine, AOUI Policlinico G.B. Rossi, University of Verona, Verona, Italy.
Biletta E; Anatomic Pathology ASL Biella, Biella, Italy.
Luinetti O; Anatomic Pathology Unit, Department of Molecular Medicine, University of Pavia and Fondazione IRCCS San Matteo Hospital, Pavia, Italy.
Pedrazzoli P; Department of Internal Medicine, University of Pavia and Fondazione IRCCS San Matteo Hospital, Pavia, Italy.; Oncology Unit, IRCCS San Matteo Hospital, Pavia, Italy.
Pietrabissa A; Department of Surgery, General Surgery II, University of Pavia and Fondazione IRCCS San Matteo Hospital, Pavia, Italy.
Corazza GR; Department of Internal Medicine, University of Pavia and Fondazione IRCCS San Matteo Hospital, Pavia, Italy.
Solcia E; Anatomic Pathology Unit, Department of Molecular Medicine, University of Pavia and Fondazione IRCCS San Matteo Hospital, Pavia, Italy.
Paulli M; Anatomic Pathology Unit, Department of Molecular Medicine, University of Pavia and Fondazione IRCCS San Matteo Hospital, Pavia, Italy.
Di Sabatino A; Department of Internal Medicine, University of Pavia and Fondazione IRCCS San Matteo Hospital, Pavia, Italy.
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Źródło :
Annals of surgical oncology [Ann Surg Oncol] 2021 Feb; Vol. 28 (2), pp. 1167-1177. Date of Electronic Publication: 2020 Aug 05.
Typ publikacji :
Journal Article
MeSH Terms :
Adenocarcinoma*/genetics
Colorectal Neoplasms*
DNA Mismatch Repair/genetics ; Female ; Humans ; Male ; Microsatellite Instability ; Mismatch Repair Endonuclease PMS2/genetics ; Mismatch Repair Endonuclease PMS2/metabolism ; MutL Protein Homolog 1/genetics ; MutL Protein Homolog 1/metabolism ; MutS Homolog 2 Protein/genetics ; MutS Homolog 2 Protein/metabolism ; Prognosis
Czasopismo naukowe
Tytuł :
Correlation of MSH2 exonic deletions and protein downregulation with breast cancer biomarkers and outcome in Pakistani women/patients.
Autorzy :
Malik SS; Department of Zoology, University of Gujrat, Gujrat, Pakistan. .; Microbiology & Biotechnology Research Lab., Fatima Jinnah Women University, The Mall Rawalpindi, Rawalpindi, Punjab, Pakistan. .
Mubarik S; Department of Epidemiology and Biostatistics, School of Health Sciences, Wuhan University, Wuhan, 430071, Hubei, China.
Aftab A; Department of Biological Sciences, International Islamic University, Sector H10, Islamabad, Pakistan.
Khan R; The CAS Key Laboratory of Innate Immunity and Chronic Diseases, School of Life Sciences, University of Science and Technology of China, Huangshan Road, Hefei, 230027, Anhui, China.
Masood N; Microbiology & Biotechnology Research Lab., Fatima Jinnah Women University, The Mall Rawalpindi, Rawalpindi, Punjab, Pakistan.
Asif M; Department of Histopathology, Armed Forces Institute of Pathology, Rawalpindi, Pakistan.
Bano R; Breast Clinic, Combined Military Hospital, Rawalpindi, Pakistan.
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Źródło :
Environmental science and pollution research international [Environ Sci Pollut Res Int] 2021 Jan; Vol. 28 (3), pp. 3066-3077. Date of Electronic Publication: 2020 Sep 09.
Typ publikacji :
Journal Article
MeSH Terms :
Biomarkers, Tumor*/genetics
Breast Neoplasms*/genetics
Sequence Deletion*
DNA Mismatch Repair ; Down-Regulation ; Exons ; Female ; Humans ; MutL Protein Homolog 1/genetics ; MutL Protein Homolog 1/metabolism ; MutS Homolog 2 Protein/genetics ; MutS Homolog 2 Protein/metabolism ; Pakistan ; Proteomics
Czasopismo naukowe
Tytuł :
Clinicopathologic characteristics and outcomes of endometrial Cancer patients with mismatch repair deficiency in the era of universal Lynch syndrome screening.
Autorzy :
Carr C; Department of Obstetrics and Gynecology, Divison of Gynecologic Oncology, Icahan School of Medicine at Mount Sinai, New York, United States of America.
Son J; Department of Obstetrics and Gynecology and Women's Health Institute, Cleveland Clinic, Cleveland, OH, United States of America.
Yao M; Department of Quantitative Health Sciences, Seciton of Biostatistics, Cleveland Clinic, Cleveland, OH, United States of America.
Priyadarshini A; Department of Obstetrics and Gynecology and Women's Health Institute, Cleveland Clinic, Cleveland, OH, United States of America.
Marquard J; Genomic Medicine Institute, Cleveland Clinic, Cleveland, OH, United States of America.
Vargas R; Department of Obstetrics and Gynecology and Women's Health Institute, Cleveland Clinic, Cleveland, OH, United States of America.
Michener C; Department of Obstetrics and Gynecology and Women's Health Institute, Cleveland Clinic, Cleveland, OH, United States of America.
AlHilli MM; Department of Obstetrics and Gynecology and Women's Health Institute, Cleveland Clinic, Cleveland, OH, United States of America. Electronic address: .
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Źródło :
Gynecologic oncology [Gynecol Oncol] 2020 Dec; Vol. 159 (3), pp. 712-720. Date of Electronic Publication: 2020 Oct 10.
Typ publikacji :
Journal Article
MeSH Terms :
DNA Mismatch Repair*
Carcinoma, Endometrioid/*mortality
Colorectal Neoplasms, Hereditary Nonpolyposis/*diagnosis
Early Detection of Cancer/*statistics & numerical data
Endometrial Neoplasms/*mortality
Age Factors ; Aged ; Carcinoma, Endometrioid/diagnosis ; Carcinoma, Endometrioid/genetics ; Carcinoma, Endometrioid/surgery ; Colorectal Neoplasms, Hereditary Nonpolyposis/genetics ; DNA Methylation ; Early Detection of Cancer/methods ; Endometrial Neoplasms/diagnosis ; Endometrial Neoplasms/genetics ; Endometrial Neoplasms/surgery ; Endometrium/pathology ; Endometrium/surgery ; Female ; Humans ; Hysterectomy ; Middle Aged ; MutL Protein Homolog 1/deficiency ; MutL Protein Homolog 1/genetics ; Mutation ; Neoplasm Grading ; Neoplasm Invasiveness/genetics ; Neoplasm Staging ; Prognosis ; Progression-Free Survival ; Promoter Regions, Genetic/genetics ; Prospective Studies ; Registries/statistics & numerical data ; Retrospective Studies ; Risk Factors
Czasopismo naukowe
Tytuł :
Nucleus-specific linker histones Hho1 and Mlh1 form distinct protein interactions during growth, starvation and development in Tetrahymena thermophila.
Autorzy :
Nabeel-Shah S; Department of Chemistry and Biology, Ryerson University, 350 Victoria St., Toronto, M5B 2K3, Canada.; Donnelly Centre, University of Toronto, Toronto, M5S 3E1, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, M5S 1A8, Canada.
Ashraf K; Department of Biology, York University, 4700 Keele St., Toronto, M3J 1P3, Canada.
Saettone A; Department of Chemistry and Biology, Ryerson University, 350 Victoria St., Toronto, M5B 2K3, Canada.
Garg J; Department of Biology, York University, 4700 Keele St., Toronto, M3J 1P3, Canada.
Derynck J; Department of Chemistry and Biology, Ryerson University, 350 Victoria St., Toronto, M5B 2K3, Canada.
Lambert JP; Department of Molecular Medicine and Cancer Research Centre, Université Laval, Quebec, Canada.; CHU de Québec Research Center, CHUL, 2705 Laurier Boulevard, Quebec, G1V 4G2, Canada.
Pearlman RE; Department of Biology, York University, 4700 Keele St., Toronto, M3J 1P3, Canada. .
Fillingham J; Department of Chemistry and Biology, Ryerson University, 350 Victoria St., Toronto, M5B 2K3, Canada. .
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Źródło :
Scientific reports [Sci Rep] 2020 Jan 13; Vol. 10 (1), pp. 168. Date of Electronic Publication: 2020 Jan 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation, Developmental*
High Mobility Group Proteins/*metabolism
Histones/*metabolism
MutL Protein Homolog 1/*metabolism
Proteome/*analysis
Protozoan Proteins/*metabolism
Tetrahymena thermophila/*growth & development
Amino Acid Sequence ; Animals ; Cell Nucleus/genetics ; Cell Nucleus/metabolism ; Chromatin/genetics ; Chromatin/metabolism ; Gene Expression Regulation ; High Mobility Group Proteins/genetics ; MutL Protein Homolog 1/genetics ; Protein Interaction Domains and Motifs ; Protozoan Proteins/genetics ; Starvation ; Tetrahymena thermophila/genetics ; Tetrahymena thermophila/metabolism
Czasopismo naukowe
Tytuł :
MLH1 deficiency leads to deregulated mitochondrial metabolism.
Autorzy :
Rashid S; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, Charterhouse Square, London, EC1M 6BQ, UK.
Freitas MO; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, Charterhouse Square, London, EC1M 6BQ, UK.
Cucchi D; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, Charterhouse Square, London, EC1M 6BQ, UK.
Bridge G; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, Charterhouse Square, London, EC1M 6BQ, UK.
Yao Z; Department of Cell and Developmental Biology, Consortium for Mitochondrial Research, University College London, London, WC1E 6BT, UK.
Gay L; Centre for Tumour Biology, Barts Cancer Institute, Queen Mary University of London, Charterhouse Square, London, EC1M 6BQ, UK.
Williams M; Centre for Tumour Biology, Barts Cancer Institute, Queen Mary University of London, Charterhouse Square, London, EC1M 6BQ, UK.
Wang J; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, Charterhouse Square, London, EC1M 6BQ, UK.
Suraweera N; Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, 4 Newark Street, London, E1 2AT, UK.
Silver A; Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, 4 Newark Street, London, E1 2AT, UK.
McDonald SAC; Centre for Tumour Biology, Barts Cancer Institute, Queen Mary University of London, Charterhouse Square, London, EC1M 6BQ, UK.
Chelala C; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, Charterhouse Square, London, EC1M 6BQ, UK.
Szabadkai G; Department of Cell and Developmental Biology, Consortium for Mitochondrial Research, University College London, London, WC1E 6BT, UK.; Department of Biomedical Sciences, University of Padua, Padua, 35131, Italy.; The Francis Crick Institute, London, NW1 1AT, UK.
Martin SA; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, Charterhouse Square, London, EC1M 6BQ, UK. .
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Źródło :
Cell death & disease [Cell Death Dis] 2019 Oct 22; Vol. 10 (11), pp. 795. Date of Electronic Publication: 2019 Oct 22.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Mitochondria/*metabolism
MutL Protein Homolog 1/*deficiency
Colorectal Neoplasms/genetics ; Colorectal Neoplasms/metabolism ; Colorectal Neoplasms/pathology ; DNA Mismatch Repair ; Electron Transport Complex I/antagonists & inhibitors ; Electron Transport Complex I/genetics ; Electron Transport Complex I/metabolism ; Endometrial Neoplasms/genetics ; Endometrial Neoplasms/metabolism ; Endometrial Neoplasms/pathology ; Female ; HCT116 Cells ; HT29 Cells ; Humans ; Male ; Mitochondria/genetics ; MutL Protein Homolog 1/genetics ; MutL Protein Homolog 1/metabolism ; Mutation ; Neoplasms/genetics ; Neoplasms/metabolism ; Neoplasms/pathology ; Ovarian Neoplasms/genetics ; Ovarian Neoplasms/metabolism ; Ovarian Neoplasms/pathology ; Rotenone/pharmacology ; Transfection
Czasopismo naukowe
Tytuł :
DNA Organization along Pachytene Chromosome Axes and Its Relationship with Crossover Frequencies.
Autorzy :
Del Priore L; INBIOMED-Instituto de Investigaciones Biomédicas, Universidad de Buenos Aires-CONICET, Facultad de Medicina, Paraguay 2155, C1121ABG Buenos Aires, Argentina.
Pigozzi MI; INBIOMED-Instituto de Investigaciones Biomédicas, Universidad de Buenos Aires-CONICET, Facultad de Medicina, Paraguay 2155, C1121ABG Buenos Aires, Argentina.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Feb 27; Vol. 22 (5). Date of Electronic Publication: 2021 Feb 27.
Typ publikacji :
Journal Article
MeSH Terms :
Crossing Over, Genetic*
Meiosis*
Recombination, Genetic*
Synaptonemal Complex*
Chromosomes, Mammalian/*genetics
DNA/*genetics
Oocytes/*metabolism
Animals ; Chickens ; DNA/chemistry ; Female ; MutL Protein Homolog 1/metabolism ; Oocytes/cytology
Czasopismo naukowe
Tytuł :
Could Aberrant Migration Explain Metachronous Germ Cell Tumors?
Autorzy :
Kubicek P; Institut d'Hématologie et d'Oncologie Pédiatrique, Lyon, France.
Fenouil T; Hospices Civils de Lyon, Department of Pathology, Lyon, France.
Jacquemus J; Centre Léon Bérard, Lyon, France.
Chapuis O; Department of Pathology, Mont-Blanc Pathologie, Argonay, France.
Fléchon A; Centre Léon Bérard, Lyon, France.
Dumesnil C; Department of Pediatric Oncology, Centre Hospitalier Universitaire, Rouen, France.
Faure-Conter C; Institut d'Hématologie et d'Oncologie Pédiatrique, Lyon, France.
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Źródło :
Cancer investigation [Cancer Invest] 2021 Feb; Vol. 39 (2), pp. 195-201. Date of Electronic Publication: 2020 Nov 06.
Typ publikacji :
Case Reports; Journal Article; Review
MeSH Terms :
Combined Modality Therapy/*methods
Neoplasms, Germ Cell and Embryonal/*diagnostic imaging
Neoplasms, Germ Cell and Embryonal/*therapy
Neoplasms, Second Primary/*diagnostic imaging
Neoplasms, Second Primary/*therapy
Adolescent ; Adult ; Checkpoint Kinase 2/genetics ; Disease Management ; Drug Resistance, Neoplasm ; Humans ; Male ; Mediastinal Neoplasms/diagnostic imaging ; Mediastinal Neoplasms/genetics ; Mediastinal Neoplasms/therapy ; MutL Protein Homolog 1/genetics ; Neoplasms, Germ Cell and Embryonal/genetics ; Neoplasms, Second Primary/genetics ; Pinealoma/diagnostic imaging ; Pinealoma/genetics ; Pinealoma/therapy ; Seminoma/diagnostic imaging ; Seminoma/genetics ; Seminoma/therapy ; Young Adult
Czasopismo naukowe
Tytuł :
Prediction Model for Gastric Cancer With DNA Mismatch Repair Deficiency.
Autorzy :
Suzuki O; Department of Digestive Tract and General Surgery, Saitama Medical Center, Saitama Medical University, Saitama, Japan; .
Yamaguchi T; Department of Surgery, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital, Tokyo, Japan.; Department of Clinical Genetics, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital, Tokyo, Japan.
Fukuchi M; Department of Digestive Tract and General Surgery, Saitama Medical Center, Saitama Medical University, Saitama, Japan.
Mochiki E; Department of Digestive Tract and General Surgery, Saitama Medical Center, Saitama Medical University, Saitama, Japan.
Arai T; Department of Pathology, Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology, Tokyo, Japan.
Akagi K; Division of Molecular Diagnosis and Cancer Prevention, Saitama Cancer Center, Saitama, Japan.
Ishida H; Department of Digestive Tract and General Surgery, Saitama Medical Center, Saitama Medical University, Saitama, Japan.
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Źródło :
Anticancer research [Anticancer Res] 2021 Feb; Vol. 41 (2), pp. 975-982.
Typ publikacji :
Journal Article
MeSH Terms :
DNA Mismatch Repair*
DNA-Binding Proteins/*deficiency
Mismatch Repair Endonuclease PMS2/*deficiency
MutL Protein Homolog 1/*deficiency
Stomach Neoplasms/*pathology
Adult ; Aged ; Aged, 80 and over ; Area Under Curve ; Biomarkers, Tumor/metabolism ; Female ; Humans ; Male ; Middle Aged ; Neoplasm Grading ; Neoplasm Invasiveness ; Sex Characteristics ; Stomach Neoplasms/metabolism ; Tumor Burden ; Young Adult
Czasopismo naukowe
Tytuł :
Lynch Syndrome: Its Impact on Urothelial Carcinoma.
Autorzy :
Lindner AK; Department of Urology, Medical University Innsbruck, 6020 Innsbruck, Austria.
Schachtner G; Department of Urology, Medical University Innsbruck, 6020 Innsbruck, Austria.
Tulchiner G; Department of Urology, Medical University Innsbruck, 6020 Innsbruck, Austria.
Thurnher M; Department of Urology, Medical University Innsbruck, 6020 Innsbruck, Austria.; Immunotherapy Unit, Department of Urology, Medical University Innsbruck, 6020 Innsbruck, Austria.
Untergasser G; Department of Internal Medicine V, Medical University Innsbruck, 6020 Innsbruck, Austria.; Experimental Oncogenomic Group, Tyrolean Cancer Research Institute, 6020 Innsbruck, Austria.
Obrist P; Pathology Laboratory Obrist and Brunhuber, 6511 Zams, Austria.
Pipp I; Clinical Pathology and Cytodiagnostics, tirol-kliniken, 6020 Innsbruck, Austria.
Steinkohl F; Department of Radiology, Medical University Innsbruck, 6020 Innsbruck, Austria.
Horninger W; Department of Urology, Medical University Innsbruck, 6020 Innsbruck, Austria.
Culig Z; Department of Urology, Medical University Innsbruck, 6020 Innsbruck, Austria.
Pichler R; Department of Urology, Medical University Innsbruck, 6020 Innsbruck, Austria.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jan 07; Vol. 22 (2). Date of Electronic Publication: 2021 Jan 07.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Genetic Predisposition to Disease*
Carcinoma/*genetics
Colorectal Neoplasms, Hereditary Nonpolyposis/*genetics
Urothelium/*metabolism
Carcinoma/complications ; Carcinoma/pathology ; Colorectal Neoplasms, Hereditary Nonpolyposis/complications ; Colorectal Neoplasms, Hereditary Nonpolyposis/pathology ; DNA Mismatch Repair/genetics ; DNA-Binding Proteins/genetics ; Humans ; Microsatellite Instability ; Mismatch Repair Endonuclease PMS2/genetics ; MutL Protein Homolog 1/genetics ; MutS Homolog 2 Protein/genetics ; Urothelium/pathology
Czasopismo naukowe
Tytuł :
Failure to recombine is a common feature of human oogenesis.
Autorzy :
Hassold T; School of Molecular Biosciences, Washington State University, Pullman, WA 99164, USA. Electronic address: .
Maylor-Hagen H; School of Molecular Biosciences, Washington State University, Pullman, WA 99164, USA.
Wood A; School of Molecular Biosciences, Washington State University, Pullman, WA 99164, USA.
Gruhn J; School of Molecular Biosciences, Washington State University, Pullman, WA 99164, USA; DNRF Center for Chromosome Stability, Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, NK 2200, Denmark.
Hoffmann E; DNRF Center for Chromosome Stability, Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, NK 2200, Denmark.
Broman KW; Department of Biostatistics and Medical Informatics, University of Wisconsin, Madison, WI 53706, USA.
Hunt P; School of Molecular Biosciences, Washington State University, Pullman, WA 99164, USA.
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Źródło :
American journal of human genetics [Am J Hum Genet] 2021 Jan 07; Vol. 108 (1), pp. 16-24. Date of Electronic Publication: 2020 Dec 10.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Oogenesis/*genetics
Recombination, Genetic/*genetics
Adolescent ; Adult ; Aneuploidy ; Chromosomes, Human, Pair 21/genetics ; Chromosomes, Human, Pair 22/genetics ; Female ; Humans ; Meiosis/genetics ; MutL Protein Homolog 1/genetics ; Nondisjunction, Genetic/genetics ; Oocytes/physiology ; Pregnancy ; Young Adult
Czasopismo naukowe

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