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Wyszukujesz frazę ""MutL Protein Homolog 1"" wg kryterium: Temat


Tytuł :
DACH1 mutation frequency in endometrial cancer is associated with high tumor mutation burden.
Autorzy :
Riggs MJ; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Kentucky, Lexington, Kentucky, United States of America.
Lin N; College of Pharmacy, University of Kentucky, Lexington, Kentucky, United States of America.
Wang C; Department of Biostatistics, College of Public Health, University of Kentucky, Lexington, Kentucky, United States of America.; Markey Cancer Center, University of Kentucky, Lexington, Kentucky, United States of America.
Piecoro DW; Division of Pathology, Department of Pathology and Laboratory Medicine, University of Kentucky, Lexington, Kentucky, United States of America.
Miller RW; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Kentucky, Lexington, Kentucky, United States of America.; Markey Cancer Center, University of Kentucky, Lexington, Kentucky, United States of America.
Hampton OA; Department of Bioinformatics and Biostatistics, M2Gen, Tampa, Florida, United States of America.
Rao M; Department of Pharmacy Practice, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Ueland FR; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Kentucky, Lexington, Kentucky, United States of America.; Markey Cancer Center, University of Kentucky, Lexington, Kentucky, United States of America.
Kolesar JM; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Kentucky, Lexington, Kentucky, United States of America.; College of Pharmacy, University of Kentucky, Lexington, Kentucky, United States of America.; Markey Cancer Center, University of Kentucky, Lexington, Kentucky, United States of America.
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Źródło :
PloS one [PLoS One] 2020 Dec 30; Vol. 15 (12), pp. e0244558. Date of Electronic Publication: 2020 Dec 30 (Print Publication: 2020).
Typ publikacji :
Comparative Study; Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Mutation Rate*
Endometrial Neoplasms/*pathology
Eye Proteins/*genetics
Transcription Factors/*genetics
Aged ; DNA Polymerase II/genetics ; Databases, Genetic ; Endometrial Neoplasms/genetics ; Female ; Humans ; Kentucky ; Microsatellite Instability ; Middle Aged ; Mismatch Repair Endonuclease PMS2/genetics ; MutL Protein Homolog 1/genetics ; Neoplasm Grading ; Poly-ADP-Ribose Binding Proteins/genetics ; Prevalence ; Prognosis ; Registries ; Sequence Analysis, RNA ; Whole Exome Sequencing
Czasopismo naukowe
Tytuł :
Protein expression-based classification of gastric cancer by immunohistochemistry of tissue microarray.
Autorzy :
Zhao C; Department of Gastroenterology, Guangzhou First People's Hospital, Medical School, South China University of Technology, Guangzhou, China.; Department of Gastroenterology, Guangzhou Digestive Disease Center, Guangzhou First People's Hospital, Guangzhou Medical University, Guangzhou, China.
Feng Z; Department of Gastroenterology, Guangzhou First People's Hospital, Medical School, South China University of Technology, Guangzhou, China.; Department of Gastroenterology, Guangzhou Digestive Disease Center, Guangzhou First People's Hospital, Guangzhou Medical University, Guangzhou, China.
He H; Department of Gastroenterology, Guangzhou First People's Hospital, Medical School, South China University of Technology, Guangzhou, China.; Department of Gastroenterology, Guangzhou Digestive Disease Center, Guangzhou First People's Hospital, Guangzhou Medical University, Guangzhou, China.
Zang D; Department of Pathology, The First Affiliated Hospital of Xinxiang Medical University, Xinxiang, China.
Du H; Department of Pathology, Guangzhou First People's Hospital, Medical School, South China University of Technology, Guangzhou, China.
Huang H; Department of Gastroenterology, Guangzhou First People's Hospital, Medical School, South China University of Technology, Guangzhou, China.; Department of Gastroenterology, Guangzhou Digestive Disease Center, Guangzhou First People's Hospital, Guangzhou Medical University, Guangzhou, China.
Du Y; Department of Gastroenterology, Guangzhou First People's Hospital, Medical School, South China University of Technology, Guangzhou, China.; Department of Gastroenterology, Guangzhou Digestive Disease Center, Guangzhou First People's Hospital, Guangzhou Medical University, Guangzhou, China.
He J; Department of Gastroenterology, Guangzhou First People's Hospital, Medical School, South China University of Technology, Guangzhou, China.; Department of Gastroenterology, Guangzhou Digestive Disease Center, Guangzhou First People's Hospital, Guangzhou Medical University, Guangzhou, China.
Zhou Y; Department of Gastroenterology, Guangzhou First People's Hospital, Medical School, South China University of Technology, Guangzhou, China.; Department of Gastroenterology, Guangzhou Digestive Disease Center, Guangzhou First People's Hospital, Guangzhou Medical University, Guangzhou, China.
Nie Y; Department of Gastroenterology, Guangzhou First People's Hospital, Medical School, South China University of Technology, Guangzhou, China.; Department of Gastroenterology, Guangzhou Digestive Disease Center, Guangzhou First People's Hospital, Guangzhou Medical University, Guangzhou, China.
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Źródło :
PloS one [PLoS One] 2020 Oct 23; Vol. 15 (10), pp. e0238836. Date of Electronic Publication: 2020 Oct 23 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Neoplasm Proteins/*metabolism
Stomach Neoplasms/*classification
Stomach Neoplasms/*metabolism
Adult ; Aged ; Aged, 80 and over ; Antigens, CD/metabolism ; Biomarkers, Tumor/metabolism ; Cadherins/metabolism ; China ; Cohort Studies ; Cyclin-Dependent Kinase Inhibitor p21/metabolism ; DNA Mismatch Repair ; DNA-Binding Proteins/metabolism ; Female ; Humans ; Immunohistochemistry ; Male ; Middle Aged ; Mismatch Repair Endonuclease PMS2/metabolism ; MutL Protein Homolog 1/metabolism ; MutS Homolog 2 Protein/metabolism ; Prognosis ; Retrospective Studies ; Stomach Neoplasms/pathology ; Tissue Array Analysis
Czasopismo naukowe
Tytuł :
MLH1 focus mapping in the guinea fowl (Numida meleagris) give insights into the crossover landscapes in birds.
Autorzy :
Del Priore L; INBIOMED (CONICET-UBA), Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires, Argentina.
Pigozzi MI; INBIOMED (CONICET-UBA), Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires, Argentina.
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Źródło :
PloS one [PLoS One] 2020 Oct 05; Vol. 15 (10), pp. e0240245. Date of Electronic Publication: 2020 Oct 05 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
MutL Protein Homolog 1/*metabolism
Synaptonemal Complex/*metabolism
Animals ; Chickens ; Karyotype ; Oocytes ; Phylogeny
Czasopismo naukowe
Tytuł :
Targeted sequencing of genes associated with the mismatch repair pathway in patients with endometrial cancer.
Autorzy :
Singh AK; Department of Medical Genetics, St. Olavs Hospital, Trondheim, Norway.; Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, NTNU-Norwegian University of Science and Technology, Trondheim, Norway.
Talseth-Palmer B; Department of Medical Genetics, St. Olavs Hospital, Trondheim, Norway.; School of Biomedical Science and Pharmacy, Faculty of Health and Medicine, University of Newcastle and Hunter Medical Research Institute, Newcastle, Australia.; Department of Research and Development, Møre og Romsdal Hospital Trust, Molde, Norway.
McPhillips M; NSW Health Pathology, Molecular Medicine, John Hunter Hospital, Newcastle, NSW, Australia.
Lavik LAS; Department of Medical Genetics, St. Olavs Hospital, Trondheim, Norway.
Xavier A; School of Biomedical Science and Pharmacy, Faculty of Health and Medicine, University of Newcastle and Hunter Medical Research Institute, Newcastle, Australia.
Drabløs F; Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, NTNU-Norwegian University of Science and Technology, Trondheim, Norway.
Sjursen W; Department of Medical Genetics, St. Olavs Hospital, Trondheim, Norway.; Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, NTNU-Norwegian University of Science and Technology, Trondheim, Norway.
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Źródło :
PloS one [PLoS One] 2020 Jul 07; Vol. 15 (7), pp. e0235613. Date of Electronic Publication: 2020 Jul 07 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA Mismatch Repair*
Endometrial Neoplasms/*pathology
Mismatch Repair Endonuclease PMS2/*genetics
MutL Protein Homolog 1/*genetics
MutS Homolog 2 Protein/*genetics
Colorectal Neoplasms, Hereditary Nonpolyposis/genetics ; Colorectal Neoplasms, Hereditary Nonpolyposis/pathology ; DNA Copy Number Variations ; DNA, Neoplasm/blood ; DNA, Neoplasm/chemistry ; DNA, Neoplasm/metabolism ; Endometrial Neoplasms/genetics ; Exons ; Female ; High-Throughput Nucleotide Sequencing ; Humans ; Introns ; Risk Factors ; Untranslated Regions/genetics
Czasopismo naukowe
Tytuł :
Cost-effectiveness analysis of genetic diagnostic strategies for Lynch syndrome in Italy.
Autorzy :
Pastorino R; Department of Woman and Child Health and Public Health-Public Health Area, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italia.
Basile M; Università Cattolica del Sacro Cuore, Alta Scuola di Economia e Management dei Sistemi Sanitari (ALTEMS), Roma, Italia.
Tognetto A; Section of Hygiene, University Department of Life Sciences and Public Health, Università Cattolica del Sacro Cuore, Roma, Italia.
Di Marco M; Department of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy.
Grossi A; Section of Hygiene, University Department of Life Sciences and Public Health, Università Cattolica del Sacro Cuore, Roma, Italia.
Lucci-Cordisco E; Department of Laboratory and Infectious Sciences, Medical Genetics Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.; Dipartimento di Scienze della Vita e di Sanità Pubblica, Sezione di Medicina Genomica, Università Cattolica del Sacro Cuore, Rome, Italy.
Scaldaferri F; UOC Medicina Interna, Gastroenterologia e Malattie del Fegato, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
De Censi A; Medical Oncology Unit, Galliera Hospital, Genova, Italy.
Federici A; Direction of Prevention, Ministry of Health, Rome, Italy.
Villari P; Department of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy.
Genuardi M; Department of Laboratory and Infectious Sciences, Medical Genetics Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.; Dipartimento di Scienze della Vita e di Sanità Pubblica, Sezione di Medicina Genomica, Università Cattolica del Sacro Cuore, Rome, Italy.
Ricciardi W; Department of Woman and Child Health and Public Health-Public Health Area, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italia.; Section of Hygiene, University Department of Life Sciences and Public Health, Università Cattolica del Sacro Cuore, Roma, Italia.
Boccia S; Department of Woman and Child Health and Public Health-Public Health Area, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italia.; Section of Hygiene, University Department of Life Sciences and Public Health, Università Cattolica del Sacro Cuore, Roma, Italia.
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Źródło :
PloS one [PLoS One] 2020 Jul 01; Vol. 15 (7), pp. e0235038. Date of Electronic Publication: 2020 Jul 01 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Colorectal Neoplasms/*diagnosis
Colorectal Neoplasms, Hereditary Nonpolyposis/*diagnosis
Genetic Testing/*economics
Colorectal Neoplasms/economics ; Colorectal Neoplasms/epidemiology ; Colorectal Neoplasms/genetics ; Colorectal Neoplasms, Hereditary Nonpolyposis/economics ; Colorectal Neoplasms, Hereditary Nonpolyposis/epidemiology ; Colorectal Neoplasms, Hereditary Nonpolyposis/genetics ; Cost-Benefit Analysis ; DNA Mismatch Repair ; Genetic Testing/methods ; Humans ; Italy/epidemiology ; MutL Protein Homolog 1/genetics ; Pedigree ; Probability ; Quality-Adjusted Life Years
Czasopismo naukowe
Tytuł :
Investigation on the hereditary basis of colorectal cancers in an African population with frequent early onset cases.
Autorzy :
Katsidzira L; Department of Medicine, College of Health Sciences, University of Zimbabwe, Harare, Zimbabwe.; MRC/UCT Research Unit for Genomic and Precision Medicine, Division of Human Genetics, Institute of Infectious Diseases and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Vorster A; MRC/UCT Research Unit for Genomic and Precision Medicine, Division of Human Genetics, Institute of Infectious Diseases and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.; Central Analytical Facility (CAF), DNA Sequencing Unit, Stellenbosch University, Stellenbosch, South Africa.
Gangaidzo IT; Department of Medicine, College of Health Sciences, University of Zimbabwe, Harare, Zimbabwe.
Makunike-Mutasa R; Department of Histopathology, College of Health Sciences, University of Zimbabwe, Harare, Zimbabwe.
Govender D; Division of Anatomical Pathology, Faculty of Health Sciences, University of Cape Town, and National Health Laboratory Service Groote Schuur hospital, Cape Town, South Africa.
Rusakaniko S; Department of Community Medicine, College of Health Sciences, University of Zimbabwe, Harare, Zimbabwe.
Thomson S; Division of Gastroenterology, Department of Medicine, University of Cape Town, Cape Town, Groote Schuur Hospital, Cape Town, South Africa.
Matenga JA; Department of Medicine, College of Health Sciences, University of Zimbabwe, Harare, Zimbabwe.
Ramesar R; MRC/UCT Research Unit for Genomic and Precision Medicine, Division of Human Genetics, Institute of Infectious Diseases and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
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Źródło :
PloS one [PLoS One] 2019 Oct 24; Vol. 14 (10), pp. e0224023. Date of Electronic Publication: 2019 Oct 24 (Print Publication: 2019).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Genetic Predisposition to Disease*
Germ-Line Mutation*
African Continental Ancestry Group/*genetics
Colorectal Neoplasms/*genetics
Epithelial Cell Adhesion Molecule/*genetics
MutL Protein Homolog 1/*genetics
MutS Homolog 2 Protein/*genetics
Adult ; Age of Onset ; Colorectal Neoplasms/epidemiology ; Cross-Sectional Studies ; Female ; Humans ; Incidence ; Male ; Microsatellite Instability ; Middle Aged ; Prognosis ; Prospective Studies ; Zimbabwe/epidemiology
Czasopismo naukowe
Tytuł :
RPL22L1 induction in colorectal cancer is associated with poor prognosis and 5-FU resistance.
Autorzy :
Rao S; Center for Translational Medicine, Department of Surgery, George Washington University, Washington, DC, United States of America.
Peri S; Blood Cell Development and Function Program, Fox Chase Cancer Center, Philadelphia, PA, United States of America.
Hoffmann J; Experimental Pharmacology & Oncology Berlin-Buch GMBH, Berlin-Buch, Germany.
Cai KQ; Cancer Biology Program, Fox Chase Cancer Center, Philadelphia, PA, United States of America.
Harris B; Blood Cell Development and Function Program, Fox Chase Cancer Center, Philadelphia, PA, United States of America.
Rhodes M; Blood Cell Development and Function Program, Fox Chase Cancer Center, Philadelphia, PA, United States of America.
Connolly DC; Molecular Therapeutics Program, Fox Chase Cancer Center, Philadelphia, PA, United States of America.
Testa JR; Cancer Biology Program, Fox Chase Cancer Center, Philadelphia, PA, United States of America.
Wiest DL; Blood Cell Development and Function Program, Fox Chase Cancer Center, Philadelphia, PA, United States of America.
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Źródło :
PloS one [PLoS One] 2019 Oct 03; Vol. 14 (10), pp. e0222392. Date of Electronic Publication: 2019 Oct 03 (Print Publication: 2019).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Drug Resistance, Neoplasm*
Colorectal Neoplasms/*drug therapy
Colorectal Neoplasms/*metabolism
Fluorouracil/*therapeutic use
RNA-Binding Proteins/*metabolism
Ribosomal Proteins/*metabolism
Animals ; Cell Proliferation ; Colorectal Neoplasms/pathology ; DNA Modification Methylases/metabolism ; DNA Repair Enzymes/metabolism ; Humans ; Mice ; MutL Protein Homolog 1/metabolism ; Prognosis ; Proto-Oncogene Proteins/metabolism ; Tumor Suppressor Proteins/metabolism
Czasopismo naukowe
Tytuł :
The prevalence and persistence of aberrant promoter DNA methylation in benzene-exposed Chinese workers.
Autorzy :
Ren J; Henan International Collaborative Laboratory for Health Effects and Intervention of Air Pollution, Medicine, School of Public Health, Xinxiang Medical University, Xinxiang, China.
Cui JP; Henan International Collaborative Laboratory for Health Effects and Intervention of Air Pollution, Medicine, School of Public Health, Xinxiang Medical University, Xinxiang, China.
Luo M; Henan International Collaborative Laboratory for Health Effects and Intervention of Air Pollution, Medicine, School of Public Health, Xinxiang Medical University, Xinxiang, China.
Liu H; Henan International Collaborative Laboratory for Health Effects and Intervention of Air Pollution, Medicine, School of Public Health, Xinxiang Medical University, Xinxiang, China.
Hao P; Xinxiang Center for Disease Control and Prevention, Xinxiang, China.
Wang X; Henan International Collaborative Laboratory for Health Effects and Intervention of Air Pollution, Medicine, School of Public Health, Xinxiang Medical University, Xinxiang, China.
Zhang GH; Henan International Collaborative Laboratory for Health Effects and Intervention of Air Pollution, Medicine, School of Public Health, Xinxiang Medical University, Xinxiang, China.
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Źródło :
PloS one [PLoS One] 2019 Aug 05; Vol. 14 (8), pp. e0220500. Date of Electronic Publication: 2019 Aug 05 (Print Publication: 2019).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Benzene/*adverse effects
DNA Methylation/*drug effects
Environmental Pollutants/*adverse effects
Occupational Exposure/*adverse effects
Promoter Regions, Genetic/*drug effects
Adolescent ; Adult ; Aged ; Cell Line ; Female ; Humans ; Long Interspersed Nucleotide Elements/drug effects ; Male ; Middle Aged ; MutL Protein Homolog 1/genetics ; O(6)-Methylguanine-DNA Methyltransferase/genetics ; Occupational Exposure/analysis ; Young Adult
Czasopismo naukowe
Tytuł :
Downregulation of SPTAN1 is related to MLH1 deficiency and metastasis in colorectal cancer.
Autorzy :
Ackermann A; Medical Clinic I, Biomedical Research Laboratory, University Clinic Frankfurt, Frankfurt am Main, Germany.
Schrecker C; Medical Clinic I, Biomedical Research Laboratory, University Clinic Frankfurt, Frankfurt am Main, Germany.
Bon D; Institute for Biostatistics and Mathematical Modelling, Goethe University, Frankfurt am Main, Germany.
Friedrichs N; Institute of Pathology, University of Cologne Medical School, Cologne, Germany.
Bankov K; Dr. Senckenberg Institute of Pathology, University Hospital Frankfurt, Frankfurt am Main, Germany.
Wild P; Dr. Senckenberg Institute of Pathology, University Hospital Frankfurt, Frankfurt am Main, Germany.
Plotz G; Medical Clinic I, Biomedical Research Laboratory, University Clinic Frankfurt, Frankfurt am Main, Germany.
Zeuzem S; Medical Clinic I, Biomedical Research Laboratory, University Clinic Frankfurt, Frankfurt am Main, Germany.
Herrmann E; Institute for Biostatistics and Mathematical Modelling, Goethe University, Frankfurt am Main, Germany.
Hansmann ML; Dr. Senckenberg Institute of Pathology, University Hospital Frankfurt, Frankfurt am Main, Germany.
Brieger A; Medical Clinic I, Biomedical Research Laboratory, University Clinic Frankfurt, Frankfurt am Main, Germany.
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Źródło :
PloS one [PLoS One] 2019 Mar 11; Vol. 14 (3), pp. e0213411. Date of Electronic Publication: 2019 Mar 11 (Print Publication: 2019).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Carrier Proteins/*metabolism
Colorectal Neoplasms/*metabolism
Colorectal Neoplasms/*pathology
Microfilament Proteins/*metabolism
MutL Protein Homolog 1/*deficiency
Aged ; Aged, 80 and over ; Caco-2 Cells ; Carrier Proteins/antagonists & inhibitors ; Carrier Proteins/genetics ; Cell Adhesion ; Cell Line, Tumor ; Cell Movement ; Cell Survival ; Cohort Studies ; Colorectal Neoplasms/genetics ; Disease Progression ; Down-Regulation ; Female ; Gene Knockdown Techniques ; Humans ; Immunohistochemistry ; Male ; Microfilament Proteins/antagonists & inhibitors ; Microfilament Proteins/genetics ; Middle Aged ; Neoplasm Metastasis/genetics ; Neoplasm Metastasis/pathology
Czasopismo naukowe
Tytuł :
Clinical impact of endometrial cancer stratified by genetic mutational profiles, POLE mutation, and microsatellite instability.
Autorzy :
Haruma T; Department of Obstetrics and Gynecology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
Nagasaka T; Department of Clinical Oncology, Kawasaki Medical School, Kurashiki, Japan.
Nakamura K; Department of Obstetrics and Gynecology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
Haraga J; Department of Obstetrics and Gynecology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
Nyuya A; Department of Clinical Oncology, Kawasaki Medical School, Kurashiki, Japan.
Nishida T; Department of Obstetrics and Gynecology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
Goel A; Center for Gastrointestinal Research, Center for Translational Genomics and Oncology, Baylor Scott & White Research Institute, Dallas, Texas, United States of America.; Charles A Sammons Cancer Center, Baylor University Medical Center, Dallas, Texas, United States of America.
Masuyama H; Department of Obstetrics and Gynecology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
Hiramatsu Y; Department of Obstetrics and Gynecology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
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Źródło :
PloS one [PLoS One] 2018 Apr 16; Vol. 13 (4), pp. e0195655. Date of Electronic Publication: 2018 Apr 16 (Print Publication: 2018).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Microsatellite Instability*
Mutation*
DNA Polymerase II/*genetics
Endometrial Neoplasms/*genetics
Poly-ADP-Ribose Binding Proteins/*genetics
DNA Methylation ; DNA Mismatch Repair/genetics ; Endometrial Neoplasms/pathology ; Female ; Humans ; Middle Aged ; MutL Protein Homolog 1/genetics ; Promoter Regions, Genetic/genetics ; Proto-Oncogene Proteins B-raf/genetics ; Proto-Oncogene Proteins p21(ras)/genetics
Czasopismo naukowe
Tytuł :
Micronucleus-specific histone H1 is required for micronuclear chromosome integrity in Tetrahymena thermophila.
Autorzy :
Qiao J; Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, Taiyuan, Shanxi, China.
Xu J; Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, Taiyuan, Shanxi, China.; College of Life Science, Shanxi University, Taiyuan, Shanxi, China.; Institute of Evolution & Marine Biodiversity, Ocean University of China, Qingdao, Shandong, China.
Bo T; Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, Taiyuan, Shanxi, China.
Wang W; Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, Taiyuan, Shanxi, China.
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Źródło :
PloS one [PLoS One] 2017 Nov 02; Vol. 12 (11), pp. e0187475. Date of Electronic Publication: 2017 Nov 02 (Print Publication: 2017).
Typ publikacji :
Journal Article
MeSH Terms :
Cell Nucleus/*genetics
Histones/*metabolism
Tetrahymena thermophila/*genetics
Animals ; Chromosomes ; MutL Protein Homolog 1/metabolism
Czasopismo naukowe
Tytuł :
Genome-wide alteration in DNA hydroxymethylation in the sperm from bisphenol A-exposed men.
Autorzy :
Zheng H; Key Laboratory of Reproduction Regulation of NPFPC, SIPPR, IRD, Fudan University, Shanghai, China.; WHO Collaborating Center for Research in Human Reproduction, Shanghai, China.
Zhou X; Key Laboratory of Reproduction Regulation of NPFPC, SIPPR, IRD, Fudan University, Shanghai, China.; WHO Collaborating Center for Research in Human Reproduction, Shanghai, China.
Li DK; Division of Research, Kaiser Foundation Research Institute, Kaiser Permanente Northern California, Oakland, and Department of Health Research and Policy, School of Medicine, Stanford University, Stanford, California, United States of America.
Yang F; Key Laboratory of Reproduction Regulation of NPFPC, SIPPR, IRD, Fudan University, Shanghai, China.; WHO Collaborating Center for Research in Human Reproduction, Shanghai, China.
Pan H; Key Laboratory of Reproduction Regulation of NPFPC, SIPPR, IRD, Fudan University, Shanghai, China.; WHO Collaborating Center for Research in Human Reproduction, Shanghai, China.
Li T; Key Laboratory of Reproduction Regulation of NPFPC, SIPPR, IRD, Fudan University, Shanghai, China.; WHO Collaborating Center for Research in Human Reproduction, Shanghai, China.
Miao M; Key Laboratory of Reproduction Regulation of NPFPC, SIPPR, IRD, Fudan University, Shanghai, China.; WHO Collaborating Center for Research in Human Reproduction, Shanghai, China.
Li R; Key Laboratory of Reproduction Regulation of NPFPC, SIPPR, IRD, Fudan University, Shanghai, China.; WHO Collaborating Center for Research in Human Reproduction, Shanghai, China.
Yuan W; Key Laboratory of Reproduction Regulation of NPFPC, SIPPR, IRD, Fudan University, Shanghai, China.; WHO Collaborating Center for Research in Human Reproduction, Shanghai, China.
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Źródło :
PloS one [PLoS One] 2017 Jun 05; Vol. 12 (6), pp. e0178535. Date of Electronic Publication: 2017 Jun 05 (Print Publication: 2017).
Typ publikacji :
Journal Article
MeSH Terms :
Epigenesis, Genetic*
5-Methylcytosine/*analogs & derivatives
Air Pollutants, Occupational/*pharmacology
Benzhydryl Compounds/*pharmacology
Estrogens, Non-Steroidal/*pharmacology
Phenols/*pharmacology
Spermatogenesis/*drug effects
5-Methylcytosine/metabolism ; Adult ; DNA Methylation ; DNA-Binding Proteins/genetics ; DNA-Binding Proteins/metabolism ; Environmental Exposure/adverse effects ; Genome, Human ; Histones/genetics ; Histones/metabolism ; Homeodomain Proteins/genetics ; Homeodomain Proteins/metabolism ; Humans ; Hydroxylation ; Male ; Middle Aged ; MutL Protein Homolog 1/genetics ; MutL Protein Homolog 1/metabolism ; Promoter Regions, Genetic ; Protein Isoforms/genetics ; Protein Isoforms/metabolism ; Sperm Count ; Spermatozoa/drug effects ; Spermatozoa/metabolism
Czasopismo naukowe
Tytuł :
Systematic immunohistochemical screening for mismatch repair and ERCC1 gene expression from colorectal cancers in China: Clinicopathological characteristics and effects on survival.
Autorzy :
Li P; Department of Hematology and Oncology, Medizinische Klinik und Poliklinik IV, Ludwig Maximilians University, Munich, Germany.
Xiao Z; Department of Colorectal Surgery, State Key Laboratory of Oncology in South China, Sun Yat-sen University Cancer Center, Guangzhou, China.
Braciak TA; Department of Hematology and Oncology, Medizinische Klinik und Poliklinik IV, Ludwig Maximilians University, Munich, Germany.
Ou Q; Department of Colorectal Surgery, State Key Laboratory of Oncology in South China, Sun Yat-sen University Cancer Center, Guangzhou, China.
Chen G; Department of Colorectal Surgery, State Key Laboratory of Oncology in South China, Sun Yat-sen University Cancer Center, Guangzhou, China.
Oduncu FS; Department of Hematology and Oncology, Medizinische Klinik und Poliklinik IV, Ludwig Maximilians University, Munich, Germany.
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Źródło :
PloS one [PLoS One] 2017 Aug 02; Vol. 12 (8), pp. e0181615. Date of Electronic Publication: 2017 Aug 02 (Print Publication: 2017).
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression*
Colorectal Neoplasms/*pathology
DNA-Binding Proteins/*metabolism
Endonucleases/*metabolism
Mismatch Repair Endonuclease PMS2/*metabolism
MutL Protein Homolog 1/*metabolism
MutS Homolog 2 Protein/*metabolism
Adult ; Aged ; Aged, 80 and over ; China ; Colorectal Neoplasms/metabolism ; DNA Mismatch Repair ; Female ; Humans ; Male ; Middle Aged ; Prognosis ; Survival Analysis ; Young Adult
Czasopismo naukowe
Tytuł :
TP53 Polymorphisms and Colorectal Cancer Risk in Patients with Lynch Syndrome in Taiwan: A Retrospective Cohort Study.
Autorzy :
Kamiza AB; School of Public Health, College of Public Health and Nutrition, Taipei Medical University, Taipei, Taiwan.
Hsieh LL; Department of Public Health, College of Medicine, Chang Gung University, Tao-Yuan, Taiwan.
Tang R; Colorectal Section, Department of Surgery, Chang Gung Memorial Hospital, Tao-Yuan, Taiwan.; School of Medicine, Chang Gung University, Tao-Yuan, Taiwan.
Chien HT; Department of Public Health, College of Medicine, Chang Gung University, Tao-Yuan, Taiwan.
Lai CH; Department of Public Health, College of Medicine, Chang Gung University, Tao-Yuan, Taiwan.
Chiu LL; Department of Public Health, College of Medicine, Chang Gung University, Tao-Yuan, Taiwan.; Department of Nutrition and Health Sciences, Chang Gung University of Science and Technology, Tao-Yuan, Taiwan.
Lo TP; Institute of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan.
Hung KY; Institute of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan.
You JF; Colorectal Section, Department of Surgery, Chang Gung Memorial Hospital, Tao-Yuan, Taiwan.; School of Medicine, Chang Gung University, Tao-Yuan, Taiwan.
Wang WC; Ph.D. Program for Translational Medicine, College of Medical Science and Technology, Taipei Medical University, Taipei, Taiwan.
Hsiung CA; Institute of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan.
Yeh CC; School of Public Health, College of Public Health and Nutrition, Taipei Medical University, Taipei, Taiwan.; Department of Public Health, China Medical University, Taichung, Taiwan.
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Źródło :
PloS one [PLoS One] 2016 Dec 01; Vol. 11 (12), pp. e0167354. Date of Electronic Publication: 2016 Dec 01 (Print Publication: 2016).
Typ publikacji :
Journal Article
MeSH Terms :
Genetic Predisposition to Disease*
Colorectal Neoplasms/*genetics
Colorectal Neoplasms, Hereditary Nonpolyposis/*genetics
Tumor Suppressor Protein p53/*genetics
Adult ; Colorectal Neoplasms/complications ; Colorectal Neoplasms/pathology ; Colorectal Neoplasms, Hereditary Nonpolyposis/complications ; Colorectal Neoplasms, Hereditary Nonpolyposis/pathology ; Female ; Genetic Association Studies ; Genotype ; Germ-Line Mutation ; Haplotypes ; Humans ; Male ; Middle Aged ; MutL Protein Homolog 1/genetics ; MutS Homolog 2 Protein/genetics ; Polymorphism, Single Nucleotide/genetics ; Retrospective Studies ; Risk Factors ; Taiwan
Czasopismo naukowe
Tytuł :
Cost-Effectiveness Analysis of Different Genetic Testing Strategies for Lynch Syndrome in Taiwan.
Autorzy :
Chen YE; Department of Insurance, Tamkang University, Tamsui Dist., New Taipei City, 251, Taiwan.
Kao SS; Division of Gastroenterology, Department of Internal Medicine, Kaohsiung Veterans General Hospital, Kaohsiung, 813, Taiwan.
Chung RH; Institute of Population Health Sciences, National Health Research Institutes, Zhunan, 350, Taiwan.
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Źródło :
PloS one [PLoS One] 2016 Aug 02; Vol. 11 (8), pp. e0160599. Date of Electronic Publication: 2016 Aug 02 (Print Publication: 2016).
Typ publikacji :
Journal Article
MeSH Terms :
DNA Mismatch Repair*
Colorectal Neoplasms, Hereditary Nonpolyposis/*diagnosis
Colorectal Neoplasms, Hereditary Nonpolyposis/*economics
Cost-Benefit Analysis/*statistics & numerical data
Genetic Testing/*economics
Proto-Oncogene Proteins B-raf/*genetics
Adult ; Aged ; Colorectal Neoplasms, Hereditary Nonpolyposis/genetics ; Colorectal Neoplasms, Hereditary Nonpolyposis/pathology ; DNA-Binding Proteins/genetics ; Female ; Genetic Testing/methods ; Humans ; Immunohistochemistry/economics ; Male ; Microsatellite Instability ; Middle Aged ; Mismatch Repair Endonuclease PMS2/genetics ; MutL Protein Homolog 1/genetics ; MutS Homolog 2 Protein/genetics ; Mutation Rate ; Sequence Analysis, DNA/economics ; Taiwan
Czasopismo naukowe
Tytuł :
Whole Gene Capture Analysis of 15 CRC Susceptibility Genes in Suspected Lynch Syndrome Patients.
Autorzy :
Jansen AM; Department of Human Genetics, Leiden University Medical Centre, Leiden, The Netherlands.; Department of Pathology, Leiden University Medical Centre, Leiden, The Netherlands.
Geilenkirchen MA; Department of Human Genetics, Leiden University Medical Centre, Leiden, The Netherlands.
van Wezel T; Department of Pathology, Leiden University Medical Centre, Leiden, The Netherlands.
Jagmohan-Changur SC; Department of Human Genetics, Leiden University Medical Centre, Leiden, The Netherlands.
Ruano D; Department of Pathology, Leiden University Medical Centre, Leiden, The Netherlands.
van der Klift HM; Department of Human Genetics, Leiden University Medical Centre, Leiden, The Netherlands.
van den Akker BE; Department of Pathology, Leiden University Medical Centre, Leiden, The Netherlands.
Laros JF; Department of Human Genetics, Leiden University Medical Centre, Leiden, The Netherlands.
van Galen M; Department of Human Genetics, Leiden University Medical Centre, Leiden, The Netherlands.
Wagner A; Department of Clinical Genetics, Erasmus University Medical Centre, Rotterdam, The Netherlands.
Letteboer TG; Department of Medical Genetics, University Medical Centre Utrecht, Utrecht, The Netherlands.
Gómez-García EB; Department of Clinical Genetics, University Hospital Maastricht, Maastricht, The Netherlands.
Tops CM; Department of Clinical Genetics, Leiden University Medical Centre, Leiden, The Netherlands.
Vasen HF; Department of Gastroenterology and Hepatology, Leiden University Medical Centre, Leiden, The Netherlands.
Devilee P; Department of Human Genetics, Leiden University Medical Centre, Leiden, The Netherlands.
Hes FJ; Department of Clinical Genetics, Leiden University Medical Centre, Leiden, The Netherlands.
Morreau H; Department of Pathology, Leiden University Medical Centre, Leiden, The Netherlands.
Wijnen JT; Department of Human Genetics, Leiden University Medical Centre, Leiden, The Netherlands.; Department of Clinical Genetics, Leiden University Medical Centre, Leiden, The Netherlands.
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Źródło :
PloS one [PLoS One] 2016 Jun 14; Vol. 11 (6), pp. e0157381. Date of Electronic Publication: 2016 Jun 14 (Print Publication: 2016).
Typ publikacji :
Journal Article
MeSH Terms :
DNA Methylation*
DNA Mismatch Repair*
Gene Expression Regulation, Neoplastic*
Colorectal Neoplasms/*genetics
Colorectal Neoplasms, Hereditary Nonpolyposis/*genetics
Cohort Studies ; Colon/metabolism ; Colon/pathology ; Colorectal Neoplasms/pathology ; Colorectal Neoplasms, Hereditary Nonpolyposis/pathology ; Germ-Line Mutation ; Humans ; Leukocytes/metabolism ; Leukocytes/pathology ; Middle Aged ; MutL Protein Homolog 1/genetics ; Rectum/metabolism ; Rectum/pathology
Czasopismo naukowe
Tytuł :
Meiotic Recombination Analyses in Pigs Carrying Different Balanced Structural Chromosomal Rearrangements.
Autorzy :
Mary N; INRA, UMR1388 Génétique, Physiologie et Systèmes d'Elevage, Castanet-Tolosan, France.; Université de Toulouse INPT ENSAT, UMR1388 Génétique, Physiologie et Systèmes d'Elevage, Castanet-Tolosan, France.; Université de Toulouse INPT ENVT, UMR1388 Génétique, Physiologie et Systèmes d'Elevage, Toulouse, France.
Barasc H; Université de Toulouse INPT ENVT, UMR1388 Génétique, Physiologie et Systèmes d'Elevage, Toulouse, France.; Université de Toulouse INPT ENSAT, UMR1388 Génétique, Physiologie et Systèmes d'Elevage, Castanet-Tolosan, France.; INRA, UMR1388 Génétique, Physiologie et Systèmes d'Elevage, Castanet-Tolosan, France.
Ferchaud S; UE1372 GenESI Génétique, Expérimentation et Système Innovants, Surgères, France.
Priet A; UE1372 GenESI Génétique, Expérimentation et Système Innovants, Surgères, France.
Calgaro A; Université de Toulouse INPT ENVT, UMR1388 Génétique, Physiologie et Systèmes d'Elevage, Toulouse, France.; Université de Toulouse INPT ENSAT, UMR1388 Génétique, Physiologie et Systèmes d'Elevage, Castanet-Tolosan, France.; INRA, UMR1388 Génétique, Physiologie et Systèmes d'Elevage, Castanet-Tolosan, France.
Loustau-Dudez AM; INRA, UMR1388 Génétique, Physiologie et Systèmes d'Elevage, Castanet-Tolosan, France.; Université de Toulouse INPT ENSAT, UMR1388 Génétique, Physiologie et Systèmes d'Elevage, Castanet-Tolosan, France.; Université de Toulouse INPT ENVT, UMR1388 Génétique, Physiologie et Systèmes d'Elevage, Toulouse, France.
Bonnet N; Université de Toulouse INPT ENVT, UMR1388 Génétique, Physiologie et Systèmes d'Elevage, Toulouse, France.; Université de Toulouse INPT ENSAT, UMR1388 Génétique, Physiologie et Systèmes d'Elevage, Castanet-Tolosan, France.; INRA, UMR1388 Génétique, Physiologie et Systèmes d'Elevage, Castanet-Tolosan, France.
Yerle M; INRA, UMR1388 Génétique, Physiologie et Systèmes d'Elevage, Castanet-Tolosan, France.; Université de Toulouse INPT ENSAT, UMR1388 Génétique, Physiologie et Systèmes d'Elevage, Castanet-Tolosan, France.; Université de Toulouse INPT ENVT, UMR1388 Génétique, Physiologie et Systèmes d'Elevage, Toulouse, France.
Ducos A; Université de Toulouse INPT ENVT, UMR1388 Génétique, Physiologie et Systèmes d'Elevage, Toulouse, France.; Université de Toulouse INPT ENSAT, UMR1388 Génétique, Physiologie et Systèmes d'Elevage, Castanet-Tolosan, France.; INRA, UMR1388 Génétique, Physiologie et Systèmes d'Elevage, Castanet-Tolosan, France.
Pinton A; INRA, UMR1388 Génétique, Physiologie et Systèmes d'Elevage, Castanet-Tolosan, France.; Université de Toulouse INPT ENSAT, UMR1388 Génétique, Physiologie et Systèmes d'Elevage, Castanet-Tolosan, France.; Université de Toulouse INPT ENVT, UMR1388 Génétique, Physiologie et Systèmes d'Elevage, Toulouse, France.
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Źródło :
PloS one [PLoS One] 2016 Apr 28; Vol. 11 (4), pp. e0154635. Date of Electronic Publication: 2016 Apr 28 (Print Publication: 2016).
Typ publikacji :
Journal Article
MeSH Terms :
Chromosome Inversion/*genetics
Chromosome Inversion/*veterinary
Chromosome Pairing/*physiology
Meiosis/*genetics
MutL Protein Homolog 1/*genetics
Sus scrofa/*genetics
Translocation, Genetic/*genetics
Animals ; Crossing Over, Genetic/genetics ; DNA Breaks, Double-Stranded ; DNA Repair/genetics ; In Situ Hybridization, Fluorescence ; Male ; Sister Chromatid Exchange/genetics ; Swine
Czasopismo naukowe
Tytuł :
Evidence of a Mild Mutator Phenotype in Cambodian Plasmodium falciparum Malaria Parasites.
Autorzy :
Lee AH; Department of Microbiology and Immunology, Columbia University, New York, New York, United States of America.
Fidock DA; Department of Microbiology and Immunology, Columbia University, New York, New York, United States of America.; Division of Infectious Diseases, Department of Medicine, Columbia University, New York, New York, United States of America.
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Źródło :
PloS one [PLoS One] 2016 Apr 21; Vol. 11 (4), pp. e0154166. Date of Electronic Publication: 2016 Apr 21 (Print Publication: 2016).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Mutation*
Drug Resistance, Multiple/*genetics
Malaria, Falciparum/*parasitology
Plasmodium falciparum/*genetics
Alleles ; Antimalarials/pharmacology ; Artemisinins/pharmacology ; Cambodia ; Drug Resistance, Multiple/drug effects ; Gene Frequency ; Humans ; Indoles/pharmacology ; Malaria, Falciparum/diagnosis ; Malaria, Falciparum/drug therapy ; MutL Protein Homolog 1/genetics ; Phenotype ; Plasmodium falciparum/drug effects ; Protozoan Proteins/genetics ; Sodium-Potassium-Exchanging ATPase/genetics ; Spiro Compounds/pharmacology
Czasopismo naukowe
Tytuł :
The hMLH1 -93G>A Polymorphism and Risk of Ovarian Cancer in the Chinese Population.
Autorzy :
Niu L; Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China.
Li S; Department of Gynecology Oncology, Cancer Hospital, Chinese Academy of Medical Sciences, Beijing, China.
Liang H; Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China.
Li H; Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China; Department of Gynecology Oncology, Cancer Hospital, Chinese Academy of Medical Sciences, Beijing, China.
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Źródło :
PloS one [PLoS One] 2015 Aug 14; Vol. 10 (8), pp. e0135822. Date of Electronic Publication: 2015 Aug 14 (Print Publication: 2015).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Alleles*
Mutation, Missense*
Polymorphism, Genetic*
Adaptor Proteins, Signal Transducing/*genetics
Neoplasm Proteins/*genetics
Nuclear Proteins/*genetics
Ovarian Neoplasms/*genetics
Adaptor Proteins, Signal Transducing/biosynthesis ; Adult ; Aged ; Amino Acid Substitution ; Asian Continental Ancestry Group ; Cell Line, Tumor ; China ; Female ; Humans ; Middle Aged ; MutL Protein Homolog 1 ; Neoplasm Proteins/biosynthesis ; Nuclear Proteins/biosynthesis ; Ovarian Neoplasms/epidemiology ; Ovarian Neoplasms/metabolism ; Ovarian Neoplasms/pathology ; Risk Factors ; Transcription, Genetic
Czasopismo naukowe
Tytuł :
Clinical Significance of MLH1 Methylation and CpG Island Methylator Phenotype as Prognostic Markers in Patients with Gastric Cancer.
Autorzy :
Shigeyasu K; Department of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Okayama, Japan; Center for Epigenetics, Cancer Prevention and Cancer Genomics, Baylor Research Institute and Charles A Sammons Cancer Center, Baylor University Medical Center, Dallas, Texas, United States of America.
Nagasaka T; Department of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Okayama, Japan.
Mori Y; Department of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Okayama, Japan.
Yokomichi N; Department of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Okayama, Japan.
Kawai T; Department of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Okayama, Japan.
Fuji T; Department of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Okayama, Japan.
Kimura K; Department of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Okayama, Japan.
Umeda Y; Department of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Okayama, Japan.
Kagawa S; Department of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Okayama, Japan.
Goel A; Center for Epigenetics, Cancer Prevention and Cancer Genomics, Baylor Research Institute and Charles A Sammons Cancer Center, Baylor University Medical Center, Dallas, Texas, United States of America.
Fujiwara T; Department of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Okayama, Japan.
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Źródło :
PloS one [PLoS One] 2015 Jun 29; Vol. 10 (6), pp. e0130409. Date of Electronic Publication: 2015 Jun 29 (Print Publication: 2015).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
CpG Islands*
DNA Methylation*
Adaptor Proteins, Signal Transducing/*genetics
Nuclear Proteins/*genetics
Stomach Neoplasms/*genetics
Aged ; Cohort Studies ; Databases, Genetic ; Disease-Free Survival ; Female ; Humans ; Kaplan-Meier Estimate ; Male ; Microsatellite Instability ; Microsatellite Repeats/genetics ; Middle Aged ; Multivariate Analysis ; MutL Protein Homolog 1 ; Phenotype ; Prognosis ; Proportional Hazards Models ; Stomach Neoplasms/mortality ; Treatment Outcome
Czasopismo naukowe

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