Temat: "MutL Protein Homolog 1" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Expression of epigenetic pathway related genes in association with PD-L1, ER/PgR and MLH1 in endometrial carcinoma.
Autorzy:: Saglam O; Department of Pathology, Moffitt Cancer Center, Tampa, FL, United States of America.
Cao B; Department of Biostatistics and Bioinformatics, Moffitt Cancer Center, Tampa, FL, United States of America.
Wang X; Department of Biostatistics and Bioinformatics, Moffitt Cancer Center, Tampa, FL, United States of America.
Toruner GA; Department of Hematopathology, University of Texas MD Anderson Cancer Center, Houston, TX, United States of America.
Conejo-Garcia JR; Department of Immunology, Moffitt Cancer Center, Tampa, FL, United States of America.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2022 Feb 28; Vol. 17 (2), pp. e0264014. Date of Electronic Publication: 2022 Feb 28 (Print Publication: 2022).
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Epigenesis, Genetic*
Gene Expression Regulation, Neoplastic*
B7-H1 Antigen/*biosynthesis
Endometrial Neoplasms/*metabolism
MutL Protein Homolog 1/*biosynthesis
Neoplasm Proteins/*biosynthesis
Receptors, Progesterone/*biosynthesis
Aged ; Endometrial Neoplasms/pathology ; Female ; Humans ; Middle Aged

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Skocz do pozycji: 2.

Tytuł:: Haploinsufficiency by minute MutL homolog 1 promoter DNA methylation may represent unique phenotypes of microsatellite instability-gastric carcinogenesis.
Autorzy:: Harada H; Department of Upper-gastrointestinal Surgery, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan.
Nie Y; Department of General, Pediatric and Hepatobiliary-Pancreatic Surgery, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan.
Araki I; Department of Upper-gastrointestinal Surgery, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan.
Soeno T; Department of Upper-gastrointestinal Surgery, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan.
Chuman M; Department of Upper-gastrointestinal Surgery, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan.
Washio M; Department of Upper-gastrointestinal Surgery, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan.
Sakuraya M; Department of Upper-gastrointestinal Surgery, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan.
Ushiku H; Department of Upper-gastrointestinal Surgery, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan.
Niihara M; Department of Upper-gastrointestinal Surgery, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan.
Hosoda K; Department of Upper-gastrointestinal Surgery, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan.
Kumamoto Y; Department of General, Pediatric and Hepatobiliary-Pancreatic Surgery, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan.
Naitoh T; Department of Lower Gastrointestinal Surgery, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan.
Sangai T; Department of Breast and Thyroid Surgery, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan.
Hiki N; Department of Upper-gastrointestinal Surgery, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan.
Yamashita K; Department of Upper-gastrointestinal Surgery, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan.; Division of Advanced Surgical Oncology, Department of Research and Development Center for New Medical Frontiers, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2021 Dec 22; Vol. 16 (12), pp. e0260303. Date of Electronic Publication: 2021 Dec 22 (Print Publication: 2021).
Typ publikacji:: Journal Article
MeSH Terms:: DNA Methylation*
Microsatellite Instability*
Epstein-Barr Virus Infections/*genetics
MutL Protein Homolog 1/*genetics
Neoplasms, Multiple Primary/*surgery
Stomach Neoplasms/*surgery
Age Factors ; Cell Line, Tumor ; DNA, Viral/genetics ; Female ; Gastrectomy ; Haploinsufficiency ; Herpesvirus 4, Human/genetics ; Humans ; Male ; Neoplasms, Multiple Primary/genetics ; Neoplasms, Multiple Primary/virology ; Phenotype ; Polymerase Chain Reaction ; Promoter Regions, Genetic ; Stomach Neoplasms/genetics ; Stomach Neoplasms/virology

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Skocz do pozycji: 3.

Tytuł:: MLH1 focus mapping in the guinea fowl (Numida meleagris) give insights into the crossover landscapes in birds.
Autorzy:: Del Priore L; INBIOMED (CONICET-UBA), Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires, Argentina.
Pigozzi MI; INBIOMED (CONICET-UBA), Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires, Argentina.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2020 Oct 05; Vol. 15 (10), pp. e0240245. Date of Electronic Publication: 2020 Oct 05 (Print Publication: 2020).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: MutL Protein Homolog 1/*metabolism
Synaptonemal Complex/*metabolism
Animals ; Chickens ; Karyotype ; Oocytes ; Phylogeny

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Skocz do pozycji: 4.

Tytuł:: Targeted sequencing of genes associated with the mismatch repair pathway in patients with endometrial cancer.
Autorzy:: Singh AK; Department of Medical Genetics, St. Olavs Hospital, Trondheim, Norway.; Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, NTNU-Norwegian University of Science and Technology, Trondheim, Norway.
Talseth-Palmer B; Department of Medical Genetics, St. Olavs Hospital, Trondheim, Norway.; School of Biomedical Science and Pharmacy, Faculty of Health and Medicine, University of Newcastle and Hunter Medical Research Institute, Newcastle, Australia.; Department of Research and Development, Møre og Romsdal Hospital Trust, Molde, Norway.
McPhillips M; NSW Health Pathology, Molecular Medicine, John Hunter Hospital, Newcastle, NSW, Australia.
Lavik LAS; Department of Medical Genetics, St. Olavs Hospital, Trondheim, Norway.
Xavier A; School of Biomedical Science and Pharmacy, Faculty of Health and Medicine, University of Newcastle and Hunter Medical Research Institute, Newcastle, Australia.
Drabløs F; Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, NTNU-Norwegian University of Science and Technology, Trondheim, Norway.
Sjursen W; Department of Medical Genetics, St. Olavs Hospital, Trondheim, Norway.; Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, NTNU-Norwegian University of Science and Technology, Trondheim, Norway.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2020 Jul 07; Vol. 15 (7), pp. e0235613. Date of Electronic Publication: 2020 Jul 07 (Print Publication: 2020).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: DNA Mismatch Repair*
Endometrial Neoplasms/*pathology
Mismatch Repair Endonuclease PMS2/*genetics
MutL Protein Homolog 1/*genetics
MutS Homolog 2 Protein/*genetics
Colorectal Neoplasms, Hereditary Nonpolyposis/genetics ; Colorectal Neoplasms, Hereditary Nonpolyposis/pathology ; DNA Copy Number Variations ; DNA, Neoplasm/blood ; DNA, Neoplasm/chemistry ; DNA, Neoplasm/metabolism ; Endometrial Neoplasms/genetics ; Exons ; Female ; High-Throughput Nucleotide Sequencing ; Humans ; Introns ; Risk Factors ; Untranslated Regions/genetics

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Skocz do pozycji: 5.

Tytuł:: Investigation on the hereditary basis of colorectal cancers in an African population with frequent early onset cases.
Autorzy:: Katsidzira L; Department of Medicine, College of Health Sciences, University of Zimbabwe, Harare, Zimbabwe.; MRC/UCT Research Unit for Genomic and Precision Medicine, Division of Human Genetics, Institute of Infectious Diseases and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Vorster A; MRC/UCT Research Unit for Genomic and Precision Medicine, Division of Human Genetics, Institute of Infectious Diseases and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.; Central Analytical Facility (CAF), DNA Sequencing Unit, Stellenbosch University, Stellenbosch, South Africa.
Gangaidzo IT; Department of Medicine, College of Health Sciences, University of Zimbabwe, Harare, Zimbabwe.
Makunike-Mutasa R; Department of Histopathology, College of Health Sciences, University of Zimbabwe, Harare, Zimbabwe.
Govender D; Division of Anatomical Pathology, Faculty of Health Sciences, University of Cape Town, and National Health Laboratory Service Groote Schuur hospital, Cape Town, South Africa.
Rusakaniko S; Department of Community Medicine, College of Health Sciences, University of Zimbabwe, Harare, Zimbabwe.
Thomson S; Division of Gastroenterology, Department of Medicine, University of Cape Town, Cape Town, Groote Schuur Hospital, Cape Town, South Africa.
Matenga JA; Department of Medicine, College of Health Sciences, University of Zimbabwe, Harare, Zimbabwe.
Ramesar R; MRC/UCT Research Unit for Genomic and Precision Medicine, Division of Human Genetics, Institute of Infectious Diseases and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2019 Oct 24; Vol. 14 (10), pp. e0224023. Date of Electronic Publication: 2019 Oct 24 (Print Publication: 2019).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Genetic Predisposition to Disease*
Germ-Line Mutation*
Black People/*genetics
Colorectal Neoplasms/*genetics
Epithelial Cell Adhesion Molecule/*genetics
MutL Protein Homolog 1/*genetics
MutS Homolog 2 Protein/*genetics
Adult ; Age of Onset ; Colorectal Neoplasms/epidemiology ; Cross-Sectional Studies ; Female ; Humans ; Incidence ; Male ; Microsatellite Instability ; Middle Aged ; Prognosis ; Prospective Studies ; Zimbabwe/epidemiology

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Skocz do pozycji: 6.

Tytuł:: Downregulation of SPTAN1 is related to MLH1 deficiency and metastasis in colorectal cancer.
Autorzy:: Ackermann A; Medical Clinic I, Biomedical Research Laboratory, University Clinic Frankfurt, Frankfurt am Main, Germany.
Schrecker C; Medical Clinic I, Biomedical Research Laboratory, University Clinic Frankfurt, Frankfurt am Main, Germany.
Bon D; Institute for Biostatistics and Mathematical Modelling, Goethe University, Frankfurt am Main, Germany.
Friedrichs N; Institute of Pathology, University of Cologne Medical School, Cologne, Germany.
Bankov K; Dr. Senckenberg Institute of Pathology, University Hospital Frankfurt, Frankfurt am Main, Germany.
Wild P; Dr. Senckenberg Institute of Pathology, University Hospital Frankfurt, Frankfurt am Main, Germany.
Plotz G; Medical Clinic I, Biomedical Research Laboratory, University Clinic Frankfurt, Frankfurt am Main, Germany.
Zeuzem S; Medical Clinic I, Biomedical Research Laboratory, University Clinic Frankfurt, Frankfurt am Main, Germany.
Herrmann E; Institute for Biostatistics and Mathematical Modelling, Goethe University, Frankfurt am Main, Germany.
Hansmann ML; Dr. Senckenberg Institute of Pathology, University Hospital Frankfurt, Frankfurt am Main, Germany.
Brieger A; Medical Clinic I, Biomedical Research Laboratory, University Clinic Frankfurt, Frankfurt am Main, Germany.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2019 Mar 11; Vol. 14 (3), pp. e0213411. Date of Electronic Publication: 2019 Mar 11 (Print Publication: 2019).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Carrier Proteins/*metabolism
Colorectal Neoplasms/*metabolism
Colorectal Neoplasms/*pathology
Microfilament Proteins/*metabolism
MutL Protein Homolog 1/*deficiency
Aged ; Aged, 80 and over ; Caco-2 Cells ; Carrier Proteins/antagonists & inhibitors ; Carrier Proteins/genetics ; Cell Adhesion ; Cell Line, Tumor ; Cell Movement ; Cell Survival ; Cohort Studies ; Colorectal Neoplasms/genetics ; Disease Progression ; Down-Regulation ; Female ; Gene Knockdown Techniques ; Humans ; Immunohistochemistry ; Male ; Microfilament Proteins/antagonists & inhibitors ; Microfilament Proteins/genetics ; Middle Aged ; Neoplasm Metastasis/genetics ; Neoplasm Metastasis/pathology

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Skocz do pozycji: 7.

Tytuł:: Systematic immunohistochemical screening for mismatch repair and ERCC1 gene expression from colorectal cancers in China: Clinicopathological characteristics and effects on survival.
Autorzy:: Li P; Department of Hematology and Oncology, Medizinische Klinik und Poliklinik IV, Ludwig Maximilians University, Munich, Germany.
Xiao Z; Department of Colorectal Surgery, State Key Laboratory of Oncology in South China, Sun Yat-sen University Cancer Center, Guangzhou, China.
Braciak TA; Department of Hematology and Oncology, Medizinische Klinik und Poliklinik IV, Ludwig Maximilians University, Munich, Germany.
Ou Q; Department of Colorectal Surgery, State Key Laboratory of Oncology in South China, Sun Yat-sen University Cancer Center, Guangzhou, China.
Chen G; Department of Colorectal Surgery, State Key Laboratory of Oncology in South China, Sun Yat-sen University Cancer Center, Guangzhou, China.
Oduncu FS; Department of Hematology and Oncology, Medizinische Klinik und Poliklinik IV, Ludwig Maximilians University, Munich, Germany.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2017 Aug 02; Vol. 12 (8), pp. e0181615. Date of Electronic Publication: 2017 Aug 02 (Print Publication: 2017).
Typ publikacji:: Journal Article
MeSH Terms:: Gene Expression*
Colorectal Neoplasms/*pathology
DNA-Binding Proteins/*metabolism
Endonucleases/*metabolism
Mismatch Repair Endonuclease PMS2/*metabolism
MutL Protein Homolog 1/*metabolism
MutS Homolog 2 Protein/*metabolism
Adult ; Aged ; Aged, 80 and over ; China ; Colorectal Neoplasms/metabolism ; DNA Mismatch Repair ; Female ; Humans ; Male ; Middle Aged ; Prognosis ; Survival Analysis ; Young Adult

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Skocz do pozycji: 8.

Tytuł:: Meiotic Recombination Analyses in Pigs Carrying Different Balanced Structural Chromosomal Rearrangements.
Autorzy:: Mary N; INRA, UMR1388 Génétique, Physiologie et Systèmes d'Elevage, Castanet-Tolosan, France.; Université de Toulouse INPT ENSAT, UMR1388 Génétique, Physiologie et Systèmes d'Elevage, Castanet-Tolosan, France.; Université de Toulouse INPT ENVT, UMR1388 Génétique, Physiologie et Systèmes d'Elevage, Toulouse, France.
Barasc H; Université de Toulouse INPT ENVT, UMR1388 Génétique, Physiologie et Systèmes d'Elevage, Toulouse, France.; Université de Toulouse INPT ENSAT, UMR1388 Génétique, Physiologie et Systèmes d'Elevage, Castanet-Tolosan, France.; INRA, UMR1388 Génétique, Physiologie et Systèmes d'Elevage, Castanet-Tolosan, France.
Ferchaud S; UE1372 GenESI Génétique, Expérimentation et Système Innovants, Surgères, France.
Priet A; UE1372 GenESI Génétique, Expérimentation et Système Innovants, Surgères, France.
Calgaro A; Université de Toulouse INPT ENVT, UMR1388 Génétique, Physiologie et Systèmes d'Elevage, Toulouse, France.; Université de Toulouse INPT ENSAT, UMR1388 Génétique, Physiologie et Systèmes d'Elevage, Castanet-Tolosan, France.; INRA, UMR1388 Génétique, Physiologie et Systèmes d'Elevage, Castanet-Tolosan, France.
Loustau-Dudez AM; INRA, UMR1388 Génétique, Physiologie et Systèmes d'Elevage, Castanet-Tolosan, France.; Université de Toulouse INPT ENSAT, UMR1388 Génétique, Physiologie et Systèmes d'Elevage, Castanet-Tolosan, France.; Université de Toulouse INPT ENVT, UMR1388 Génétique, Physiologie et Systèmes d'Elevage, Toulouse, France.
Bonnet N; Université de Toulouse INPT ENVT, UMR1388 Génétique, Physiologie et Systèmes d'Elevage, Toulouse, France.; Université de Toulouse INPT ENSAT, UMR1388 Génétique, Physiologie et Systèmes d'Elevage, Castanet-Tolosan, France.; INRA, UMR1388 Génétique, Physiologie et Systèmes d'Elevage, Castanet-Tolosan, France.
Yerle M; INRA, UMR1388 Génétique, Physiologie et Systèmes d'Elevage, Castanet-Tolosan, France.; Université de Toulouse INPT ENSAT, UMR1388 Génétique, Physiologie et Systèmes d'Elevage, Castanet-Tolosan, France.; Université de Toulouse INPT ENVT, UMR1388 Génétique, Physiologie et Systèmes d'Elevage, Toulouse, France.
Ducos A; Université de Toulouse INPT ENVT, UMR1388 Génétique, Physiologie et Systèmes d'Elevage, Toulouse, France.; Université de Toulouse INPT ENSAT, UMR1388 Génétique, Physiologie et Systèmes d'Elevage, Castanet-Tolosan, France.; INRA, UMR1388 Génétique, Physiologie et Systèmes d'Elevage, Castanet-Tolosan, France.
Pinton A; INRA, UMR1388 Génétique, Physiologie et Systèmes d'Elevage, Castanet-Tolosan, France.; Université de Toulouse INPT ENSAT, UMR1388 Génétique, Physiologie et Systèmes d'Elevage, Castanet-Tolosan, France.; Université de Toulouse INPT ENVT, UMR1388 Génétique, Physiologie et Systèmes d'Elevage, Toulouse, France.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2016 Apr 28; Vol. 11 (4), pp. e0154635. Date of Electronic Publication: 2016 Apr 28 (Print Publication: 2016).
Typ publikacji:: Journal Article
MeSH Terms:: Chromosome Inversion/*genetics
Chromosome Inversion/*veterinary
Chromosome Pairing/*physiology
Meiosis/*genetics
MutL Protein Homolog 1/*genetics
Sus scrofa/*genetics
Translocation, Genetic/*genetics
Animals ; Crossing Over, Genetic/genetics ; DNA Breaks, Double-Stranded ; DNA Repair/genetics ; In Situ Hybridization, Fluorescence ; Male ; Sister Chromatid Exchange/genetics ; Swine

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