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Wyszukujesz frazę ""MutL Protein Homolog 1"" wg kryterium: Temat


Tytuł:
High concordance rate of capillary electrophoresis workflow for microsatellite instability analysis and mismatch repair (MMR) immunostaining in colorectal carcinoma.
Autorzy:
Huang W; Department of Pathology, Molecular Diagnosis Laboratory, National Cheng Kung University Hospital, Tainan, Taiwan.; Molecular Medicine Core Laboratory, Research Center of Clinical Medicine, National Cheng Kung University Hospital, Tainan, Taiwan.; Department of Medical Laboratory Science and Biotechnology, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Ho CL; Department of Pathology, Molecular Diagnosis Laboratory, National Cheng Kung University Hospital, Tainan, Taiwan.; Molecular Medicine Core Laboratory, Research Center of Clinical Medicine, National Cheng Kung University Hospital, Tainan, Taiwan.; Institute of Molecular Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Lee CT; Department of Pathology, Molecular Diagnosis Laboratory, National Cheng Kung University Hospital, Tainan, Taiwan.; Molecular Medicine Core Laboratory, Research Center of Clinical Medicine, National Cheng Kung University Hospital, Tainan, Taiwan.; Institute of Molecular Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Chen WL; Department of Pathology, Molecular Diagnosis Laboratory, National Cheng Kung University Hospital, Tainan, Taiwan.; Molecular Medicine Core Laboratory, Research Center of Clinical Medicine, National Cheng Kung University Hospital, Tainan, Taiwan.
Yang SC; Department of Pathology, Molecular Diagnosis Laboratory, National Cheng Kung University Hospital, Tainan, Taiwan.; Molecular Medicine Core Laboratory, Research Center of Clinical Medicine, National Cheng Kung University Hospital, Tainan, Taiwan.
Chow NH; Department of Pathology, Molecular Diagnosis Laboratory, National Cheng Kung University Hospital, Tainan, Taiwan.; Molecular Medicine Core Laboratory, Research Center of Clinical Medicine, National Cheng Kung University Hospital, Tainan, Taiwan.; Institute of Molecular Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Chen YL; Department of Pathology, Molecular Diagnosis Laboratory, National Cheng Kung University Hospital, Tainan, Taiwan.; Molecular Medicine Core Laboratory, Research Center of Clinical Medicine, National Cheng Kung University Hospital, Tainan, Taiwan.; Department of Medical Laboratory Science and Biotechnology, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
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Źródło:
PloS one [PLoS One] 2023 Apr 25; Vol. 18 (4), pp. e0284227. Date of Electronic Publication: 2023 Apr 25 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Microsatellite Instability*
Colorectal Neoplasms*/diagnosis
Colorectal Neoplasms*/genetics
Colorectal Neoplasms*/pathology
Humans ; DNA Mismatch Repair/genetics ; Workflow ; Microsatellite Repeats/genetics ; DNA-Binding Proteins/genetics ; Electrophoresis, Capillary ; MutL Protein Homolog 1/genetics
Czasopismo naukowe
Tytuł:
Functional characterization of MLH1 missense variants unveils mechanisms of pathogenicity and clarifies role in cancer.
Autorzy:
Mahdouani M; Laboratory of Human Cytogenetics, Molecular Genetics and Reproductive Biology, Farhat Hached University Hospital, Sousse, Tunisia.; Higher Institute of Biotechnology of Monastir, University of Monastir, Monastir, Tunisia.
Ben Ahmed S; Department of Oncology, Farhat Hached University Hospital, Sousse, Tunisia.; Faculty of Medicine Ibn El Jazzar of Sousse, University of Sousse, Sousse, Tunisia.
Hmila F; Faculty of Medicine Ibn El Jazzar of Sousse, University of Sousse, Sousse, Tunisia.; Department of General and Digestive Surgery, Farhat Hached University Hospital, Sousse, Tunisia.
Rais H; Medical Service, Salah Azaiez Institute, Tunis, Tunisia.
Ben Sghaier R; Laboratory of Human Cytogenetics, Molecular Genetics and Reproductive Biology, Farhat Hached University Hospital, Sousse, Tunisia.; Higher Institute of Biotechnology of Monastir, University of Monastir, Monastir, Tunisia.
Saad H; Laboratory of Human Cytogenetics, Molecular Genetics and Reproductive Biology, Farhat Hached University Hospital, Sousse, Tunisia.; Higher Institute of Biotechnology of Monastir, University of Monastir, Monastir, Tunisia.
Ben Said M; Laboratory of Molecular and Cellular Screening Processes, Centre of Biotechnology of Sfax, Sfax, Tunisia.
Masmoudi S; Laboratory of Molecular and Cellular Screening Processes, Centre of Biotechnology of Sfax, Sfax, Tunisia.
Hmida D; Laboratory of Human Cytogenetics, Molecular Genetics and Reproductive Biology, Farhat Hached University Hospital, Sousse, Tunisia.; Faculty of Medicine Ibn El Jazzar of Sousse, University of Sousse, Sousse, Tunisia.
Brieger A; Biomedical Research Laboratory, Department of Internal Medicine 1, University Hospital, Goethe University, Frankfurt am Main, Germany.
Zeuzem S; Biomedical Research Laboratory, Department of Internal Medicine 1, University Hospital, Goethe University, Frankfurt am Main, Germany.
Saad A; Laboratory of Human Cytogenetics, Molecular Genetics and Reproductive Biology, Farhat Hached University Hospital, Sousse, Tunisia.; Faculty of Medicine Ibn El Jazzar of Sousse, University of Sousse, Sousse, Tunisia.
Gribaa M; Laboratory of Human Cytogenetics, Molecular Genetics and Reproductive Biology, Farhat Hached University Hospital, Sousse, Tunisia.; Faculty of Medicine Ibn El Jazzar of Sousse, University of Sousse, Sousse, Tunisia.
Plotz G; Biomedical Research Laboratory, Department of Internal Medicine 1, University Hospital, Goethe University, Frankfurt am Main, Germany.
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Źródło:
PloS one [PLoS One] 2022 Dec 01; Vol. 17 (12), pp. e0278283. Date of Electronic Publication: 2022 Dec 01 (Print Publication: 2022).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Mutation, Missense*
Colorectal Neoplasms, Hereditary Nonpolyposis*/genetics
Humans ; Virulence ; DNA Mismatch Repair ; Germ-Line Mutation ; MutL Protein Homolog 1/genetics
Czasopismo naukowe
Tytuł:
A first genetic portrait of synaptonemal complex variation.
Autorzy:
Wang RJ; Laboratory of Genetics, University of Wisconsin-Madison, Madison, WI, United States of America.; Department of Biology, Indiana University, Bloomington, IN, United States of America.
Dumont BL; Laboratory of Genetics, University of Wisconsin-Madison, Madison, WI, United States of America.; The Jackson Laboratory, Bar Harbor, ME, United States of America.
Jing P; Laboratory of Genetics, University of Wisconsin-Madison, Madison, WI, United States of America.
Payseur BA; Laboratory of Genetics, University of Wisconsin-Madison, Madison, WI, United States of America.
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Źródło:
PLoS genetics [PLoS Genet] 2019 Aug 26; Vol. 15 (8), pp. e1008337. Date of Electronic Publication: 2019 Aug 26 (Print Publication: 2019).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Crossing Over, Genetic*
Genetic Variation*
MutL Protein Homolog 1/*genetics
Synaptonemal Complex/*genetics
X Chromosome/*genetics
Animals ; Chromosome Mapping/methods ; Evolution, Molecular ; Genetic Loci ; High-Throughput Screening Assays/methods ; Image Processing, Computer-Assisted ; Male ; Mice ; Microscopy, Fluorescence ; MutL Protein Homolog 1/metabolism ; Spermatocytes/metabolism ; Synaptonemal Complex/metabolism ; X Chromosome/metabolism
Czasopismo naukowe
Tytuł:
Genomic landscape of pathogenic mutation of APC, KRAS, TP53, PIK3CA, and MLH1 in Indonesian colorectal cancer.
Autorzy:
Marbun VMG; Department of General Surgery, Digestive Division, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia.
Erlina L; Department of Medical Chemistry, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia.
Lalisang TJM; Department of General Surgery, Digestive Division, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia.
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Źródło:
PloS one [PLoS One] 2022 Jun 16; Vol. 17 (6), pp. e0267090. Date of Electronic Publication: 2022 Jun 16 (Print Publication: 2022).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Colorectal Neoplasms*/pathology
Proto-Oncogene Proteins p21(ras)*/genetics
Class I Phosphatidylinositol 3-Kinases/genetics ; Genomics ; Humans ; Indonesia ; MutL Protein Homolog 1/genetics ; Mutation ; Tumor Suppressor Protein p53/genetics
Czasopismo naukowe
Tytuł:
Targeting mitochondrial DNA polymerase gamma for selective inhibition of MLH1 deficient colon cancer growth.
Autorzy:
Somuncu B; Department of Medical Biotechnology, Institute of Health Sciences, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey.
Ekmekcioglu A; Department of Medical Biotechnology, Institute of Health Sciences, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey.
Antmen FM; Department of Medical Biotechnology, Institute of Health Sciences, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey.
Ertuzun T; Department of Medical Biotechnology, Institute of Health Sciences, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey.
Deniz E; Department of Molecular Biology and Genetics, Faculty of Arts and Sciences, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey.
Keskin N; Molecular Biology, Genetics and Bioengineering Program, Faculty of Engineering and Natural Sciences, Sabanci University, Istanbul, Turkey.
Park J; Department of Pharmacology and Toxicology, University of Texas Medical Branch, Galveston, Texas, United States of America.
Yazici IE; Department of Medical Biotechnology, Institute of Health Sciences, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey.
Simsek B; Molecular Biology, Genetics and Bioengineering Program, Faculty of Engineering and Natural Sciences, Sabanci University, Istanbul, Turkey.
Erman B; Molecular Biology, Genetics and Bioengineering Program, Faculty of Engineering and Natural Sciences, Sabanci University, Istanbul, Turkey.; Department of Molecular Biology and Genetics, Faculty of Arts and Sciences, Bogazici University, Istanbul, Turkey.
Yin W; Department of Pharmacology and Toxicology, University of Texas Medical Branch, Galveston, Texas, United States of America.
Erman B; Department of Chemical and Biological Engineering, Koc University, Istanbul, Turkey.
Muftuoglu M; Department of Medical Biotechnology, Institute of Health Sciences, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey.; Department of Molecular Biology and Genetics, Faculty of Arts and Sciences, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey.
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Źródło:
PloS one [PLoS One] 2022 Jun 03; Vol. 17 (6), pp. e0268391. Date of Electronic Publication: 2022 Jun 03 (Print Publication: 2022).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Antineoplastic Agents*/therapeutic use
Colonic Neoplasms*/drug therapy
Colonic Neoplasms*/genetics
Colonic Neoplasms*/pathology
Adaptor Proteins, Signal Transducing/genetics ; Adaptor Proteins, Signal Transducing/metabolism ; DNA Methylation ; DNA Mismatch Repair ; DNA Polymerase gamma/genetics ; DNA Polymerase gamma/metabolism ; DNA, Mitochondrial/metabolism ; Female ; Humans ; Mitochondria/metabolism ; MutL Protein Homolog 1/metabolism ; Nuclear Proteins/genetics ; Nuclear Proteins/metabolism
Czasopismo naukowe
Tytuł:
Comparative molecular genomic analyses of a spontaneous rhesus macaque model of mismatch repair-deficient colorectal cancer.
Autorzy:
Ozirmak Lermi N; Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America.; School of Health Professions, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America.
Gray SB; Michale E. Keeling Center for Comparative Medicine and Research, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America.
Bowen CM; Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America.
Reyes-Uribe L; Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America.
Dray BK; Charles River Laboratories, Ashland, Ohio, United States of America.
Deng N; Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America.
Harris RA; Human Genome Sequencing Center and Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America.
Raveendran M; Human Genome Sequencing Center and Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America.
Benavides F; Department of Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America.
Hodo CL; Michale E. Keeling Center for Comparative Medicine and Research, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America.
Taggart MW; Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America.
Colbert Maresso K; Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America.
Sinha KM; Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America.
Rogers J; Human Genome Sequencing Center and Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America.
Vilar E; Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America.; Clinical Cancer Genetics Program, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America.
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Źródło:
PLoS genetics [PLoS Genet] 2022 Apr 21; Vol. 18 (4), pp. e1010163. Date of Electronic Publication: 2022 Apr 21 (Print Publication: 2022).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Colonic Neoplasms*/genetics
Colorectal Neoplasms*/genetics
Colorectal Neoplasms*/pathology
Colorectal Neoplasms, Hereditary Nonpolyposis*/genetics
Colorectal Neoplasms, Hereditary Nonpolyposis*/pathology
Animals ; DNA Methylation/genetics ; DNA Mismatch Repair/genetics ; Genomics ; Humans ; Macaca mulatta/genetics ; Mice ; Microsatellite Instability ; MutL Protein Homolog 1/genetics
Czasopismo naukowe
Tytuł:
Expression of epigenetic pathway related genes in association with PD-L1, ER/PgR and MLH1 in endometrial carcinoma.
Autorzy:
Saglam O; Department of Pathology, Moffitt Cancer Center, Tampa, FL, United States of America.
Cao B; Department of Biostatistics and Bioinformatics, Moffitt Cancer Center, Tampa, FL, United States of America.
Wang X; Department of Biostatistics and Bioinformatics, Moffitt Cancer Center, Tampa, FL, United States of America.
Toruner GA; Department of Hematopathology, University of Texas MD Anderson Cancer Center, Houston, TX, United States of America.
Conejo-Garcia JR; Department of Immunology, Moffitt Cancer Center, Tampa, FL, United States of America.
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Źródło:
PloS one [PLoS One] 2022 Feb 28; Vol. 17 (2), pp. e0264014. Date of Electronic Publication: 2022 Feb 28 (Print Publication: 2022).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Epigenesis, Genetic*
Gene Expression Regulation, Neoplastic*
B7-H1 Antigen/*biosynthesis
Endometrial Neoplasms/*metabolism
MutL Protein Homolog 1/*biosynthesis
Neoplasm Proteins/*biosynthesis
Receptors, Progesterone/*biosynthesis
Aged ; Endometrial Neoplasms/pathology ; Female ; Humans ; Middle Aged
Czasopismo naukowe
Tytuł:
Distinct DNA-binding surfaces in the ATPase and linker domains of MutLγ determine its substrate specificities and exert separable functions in meiotic recombination and mismatch repair.
Autorzy:
Claeys Bouuaert C; Molecular Biology Program, Memorial Sloan Kettering Cancer Center and Howard Hughes Medical Institute, New York, New York, United States of America.
Keeney S; Molecular Biology Program, Memorial Sloan Kettering Cancer Center and Howard Hughes Medical Institute, New York, New York, United States of America.
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Źródło:
PLoS genetics [PLoS Genet] 2017 May 15; Vol. 13 (5), pp. e1006722. Date of Electronic Publication: 2017 May 15 (Print Publication: 2017).
Typ publikacji:
Journal Article
MeSH Terms:
Crossing Over, Genetic*
DNA Mismatch Repair*
Adenosine Triphosphate/*metabolism
MutL Protein Homolog 1/*metabolism
MutL Proteins/*metabolism
Saccharomyces cerevisiae Proteins/*metabolism
Animals ; Chromosome Segregation ; DNA, Cruciform ; DNA, Single-Stranded/metabolism ; Meiosis ; MutL Protein Homolog 1/chemistry ; MutL Protein Homolog 1/genetics ; MutL Proteins/chemistry ; MutL Proteins/genetics ; Protein Binding ; Protein Domains ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae/metabolism ; Saccharomyces cerevisiae Proteins/chemistry ; Saccharomyces cerevisiae Proteins/genetics ; Sf9 Cells ; Spodoptera ; Substrate Specificity
Czasopismo naukowe
Tytuł:
The mismatch repair and meiotic recombination endonuclease Mlh1-Mlh3 is activated by polymer formation and can cleave DNA substrates in trans.
Autorzy:
Manhart CM; Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York, United States of America.
Ni X; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada.
White MA; Department of Molecular and Cellular Biology, Harvard University, Cambridge, Massachusetts, United States of America.
Ortega J; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada.
Surtees JA; Department of Biochemistry, University at Buffalo, State University of New York, Buffalo, New York, United States of America.
Alani E; Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York, United States of America.
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Źródło:
PLoS biology [PLoS Biol] 2017 Apr 28; Vol. 15 (4), pp. e2001164. Date of Electronic Publication: 2017 Apr 28 (Print Publication: 2017).
Typ publikacji:
Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
DNA, Cruciform/*metabolism
Mismatch Repair Endonuclease PMS2/*metabolism
MutL Protein Homolog 1/*metabolism
MutL Proteins/*metabolism
Saccharomyces cerevisiae Proteins/*metabolism
Amino Acid Substitution ; DNA Breaks, Double-Stranded ; DNA, Circular/chemistry ; DNA, Circular/metabolism ; DNA, Cruciform/chemistry ; DNA-Binding Proteins/chemistry ; DNA-Binding Proteins/genetics ; Enzyme Activation ; Humans ; Hydrolysis ; Mismatch Repair Endonuclease PMS2/chemistry ; Mismatch Repair Endonuclease PMS2/genetics ; Molecular Weight ; MutL Protein Homolog 1/chemistry ; MutL Protein Homolog 1/genetics ; MutL Proteins/chemistry ; MutL Proteins/genetics ; MutS Homolog 2 Protein/chemistry ; MutS Homolog 2 Protein/genetics ; MutS Homolog 3 Protein ; Mutation ; Proliferating Cell Nuclear Antigen/genetics ; Proliferating Cell Nuclear Antigen/metabolism ; Protein Multimerization ; Recombinant Fusion Proteins/chemistry ; Recombinant Fusion Proteins/metabolism ; Recombinant Proteins/chemistry ; Recombinant Proteins/metabolism ; Replication Protein C/genetics ; Replication Protein C/metabolism ; Saccharomyces cerevisiae Proteins/chemistry ; Saccharomyces cerevisiae Proteins/genetics ; Substrate Specificity
Czasopismo naukowe
Tytuł:
Haploinsufficiency by minute MutL homolog 1 promoter DNA methylation may represent unique phenotypes of microsatellite instability-gastric carcinogenesis.
Autorzy:
Harada H; Department of Upper-gastrointestinal Surgery, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan.
Nie Y; Department of General, Pediatric and Hepatobiliary-Pancreatic Surgery, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan.
Araki I; Department of Upper-gastrointestinal Surgery, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan.
Soeno T; Department of Upper-gastrointestinal Surgery, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan.
Chuman M; Department of Upper-gastrointestinal Surgery, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan.
Washio M; Department of Upper-gastrointestinal Surgery, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan.
Sakuraya M; Department of Upper-gastrointestinal Surgery, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan.
Ushiku H; Department of Upper-gastrointestinal Surgery, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan.
Niihara M; Department of Upper-gastrointestinal Surgery, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan.
Hosoda K; Department of Upper-gastrointestinal Surgery, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan.
Kumamoto Y; Department of General, Pediatric and Hepatobiliary-Pancreatic Surgery, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan.
Naitoh T; Department of Lower Gastrointestinal Surgery, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan.
Sangai T; Department of Breast and Thyroid Surgery, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan.
Hiki N; Department of Upper-gastrointestinal Surgery, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan.
Yamashita K; Department of Upper-gastrointestinal Surgery, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan.; Division of Advanced Surgical Oncology, Department of Research and Development Center for New Medical Frontiers, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan.
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Źródło:
PloS one [PLoS One] 2021 Dec 22; Vol. 16 (12), pp. e0260303. Date of Electronic Publication: 2021 Dec 22 (Print Publication: 2021).
Typ publikacji:
Journal Article
MeSH Terms:
DNA Methylation*
Microsatellite Instability*
Epstein-Barr Virus Infections/*genetics
MutL Protein Homolog 1/*genetics
Neoplasms, Multiple Primary/*surgery
Stomach Neoplasms/*surgery
Age Factors ; Cell Line, Tumor ; DNA, Viral/genetics ; Female ; Gastrectomy ; Haploinsufficiency ; Herpesvirus 4, Human/genetics ; Humans ; Male ; Neoplasms, Multiple Primary/genetics ; Neoplasms, Multiple Primary/virology ; Phenotype ; Polymerase Chain Reaction ; Promoter Regions, Genetic ; Stomach Neoplasms/genetics ; Stomach Neoplasms/virology
Czasopismo naukowe
Tytuł:
DACH1 mutation frequency in endometrial cancer is associated with high tumor mutation burden.
Autorzy:
Riggs MJ; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Kentucky, Lexington, Kentucky, United States of America.
Lin N; College of Pharmacy, University of Kentucky, Lexington, Kentucky, United States of America.
Wang C; Department of Biostatistics, College of Public Health, University of Kentucky, Lexington, Kentucky, United States of America.; Markey Cancer Center, University of Kentucky, Lexington, Kentucky, United States of America.
Piecoro DW; Division of Pathology, Department of Pathology and Laboratory Medicine, University of Kentucky, Lexington, Kentucky, United States of America.
Miller RW; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Kentucky, Lexington, Kentucky, United States of America.; Markey Cancer Center, University of Kentucky, Lexington, Kentucky, United States of America.
Hampton OA; Department of Bioinformatics and Biostatistics, M2Gen, Tampa, Florida, United States of America.
Rao M; Department of Pharmacy Practice, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Ueland FR; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Kentucky, Lexington, Kentucky, United States of America.; Markey Cancer Center, University of Kentucky, Lexington, Kentucky, United States of America.
Kolesar JM; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Kentucky, Lexington, Kentucky, United States of America.; College of Pharmacy, University of Kentucky, Lexington, Kentucky, United States of America.; Markey Cancer Center, University of Kentucky, Lexington, Kentucky, United States of America.
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Źródło:
PloS one [PLoS One] 2020 Dec 30; Vol. 15 (12), pp. e0244558. Date of Electronic Publication: 2020 Dec 30 (Print Publication: 2020).
Typ publikacji:
Comparative Study; Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Mutation Rate*
Endometrial Neoplasms/*pathology
Eye Proteins/*genetics
Transcription Factors/*genetics
Aged ; DNA Polymerase II/genetics ; Databases, Genetic ; Endometrial Neoplasms/genetics ; Female ; Humans ; Kentucky ; Microsatellite Instability ; Middle Aged ; Mismatch Repair Endonuclease PMS2/genetics ; MutL Protein Homolog 1/genetics ; Neoplasm Grading ; Poly-ADP-Ribose Binding Proteins/genetics ; Prevalence ; Prognosis ; Registries ; Sequence Analysis, RNA ; Exome Sequencing
Czasopismo naukowe
Tytuł:
Protein expression-based classification of gastric cancer by immunohistochemistry of tissue microarray.
Autorzy:
Zhao C; Department of Gastroenterology, Guangzhou First People's Hospital, Medical School, South China University of Technology, Guangzhou, China.; Department of Gastroenterology, Guangzhou Digestive Disease Center, Guangzhou First People's Hospital, Guangzhou Medical University, Guangzhou, China.
Feng Z; Department of Gastroenterology, Guangzhou First People's Hospital, Medical School, South China University of Technology, Guangzhou, China.; Department of Gastroenterology, Guangzhou Digestive Disease Center, Guangzhou First People's Hospital, Guangzhou Medical University, Guangzhou, China.
He H; Department of Gastroenterology, Guangzhou First People's Hospital, Medical School, South China University of Technology, Guangzhou, China.; Department of Gastroenterology, Guangzhou Digestive Disease Center, Guangzhou First People's Hospital, Guangzhou Medical University, Guangzhou, China.
Zang D; Department of Pathology, The First Affiliated Hospital of Xinxiang Medical University, Xinxiang, China.
Du H; Department of Pathology, Guangzhou First People's Hospital, Medical School, South China University of Technology, Guangzhou, China.
Huang H; Department of Gastroenterology, Guangzhou First People's Hospital, Medical School, South China University of Technology, Guangzhou, China.; Department of Gastroenterology, Guangzhou Digestive Disease Center, Guangzhou First People's Hospital, Guangzhou Medical University, Guangzhou, China.
Du Y; Department of Gastroenterology, Guangzhou First People's Hospital, Medical School, South China University of Technology, Guangzhou, China.; Department of Gastroenterology, Guangzhou Digestive Disease Center, Guangzhou First People's Hospital, Guangzhou Medical University, Guangzhou, China.
He J; Department of Gastroenterology, Guangzhou First People's Hospital, Medical School, South China University of Technology, Guangzhou, China.; Department of Gastroenterology, Guangzhou Digestive Disease Center, Guangzhou First People's Hospital, Guangzhou Medical University, Guangzhou, China.
Zhou Y; Department of Gastroenterology, Guangzhou First People's Hospital, Medical School, South China University of Technology, Guangzhou, China.; Department of Gastroenterology, Guangzhou Digestive Disease Center, Guangzhou First People's Hospital, Guangzhou Medical University, Guangzhou, China.
Nie Y; Department of Gastroenterology, Guangzhou First People's Hospital, Medical School, South China University of Technology, Guangzhou, China.; Department of Gastroenterology, Guangzhou Digestive Disease Center, Guangzhou First People's Hospital, Guangzhou Medical University, Guangzhou, China.
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Źródło:
PloS one [PLoS One] 2020 Oct 23; Vol. 15 (10), pp. e0238836. Date of Electronic Publication: 2020 Oct 23 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Neoplasm Proteins/*metabolism
Stomach Neoplasms/*classification
Stomach Neoplasms/*metabolism
Adult ; Aged ; Aged, 80 and over ; Antigens, CD/metabolism ; Biomarkers, Tumor/metabolism ; Cadherins/metabolism ; China ; Cohort Studies ; Cyclin-Dependent Kinase Inhibitor p21/metabolism ; DNA Mismatch Repair ; DNA-Binding Proteins/metabolism ; Female ; Humans ; Immunohistochemistry ; Male ; Middle Aged ; Mismatch Repair Endonuclease PMS2/metabolism ; MutL Protein Homolog 1/metabolism ; MutS Homolog 2 Protein/metabolism ; Prognosis ; Retrospective Studies ; Stomach Neoplasms/pathology ; Tissue Array Analysis
Czasopismo naukowe
Tytuł:
A novel function for CDK2 activity at meiotic crossover sites.
Autorzy:
Palmer N; Institute of Molecular and Cell Biology (IMCB), A*STAR (Agency for Science, Technology, and Research), Singapore, Republic of Singapore.; Department of Biochemistry, National University of Singapore (NUS), Singapore, Republic of Singapore.
Talib SZA; Institute of Molecular and Cell Biology (IMCB), A*STAR (Agency for Science, Technology, and Research), Singapore, Republic of Singapore.
Singh P; Department of Biomedical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America.
Goh CMF; Institute of Molecular and Cell Biology (IMCB), A*STAR (Agency for Science, Technology, and Research), Singapore, Republic of Singapore.
Liu K; Department of Obstetrics and Gynecology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.; Shenzhen Key Laboratory of Fertility Regulation, Center of Assisted Reproduction and Embryology, The University of Hong Kong-Shenzhen Hospital, Shenzhen, China.
Schimenti JC; Department of Biomedical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America.
Kaldis P; Institute of Molecular and Cell Biology (IMCB), A*STAR (Agency for Science, Technology, and Research), Singapore, Republic of Singapore.; Department of Biochemistry, National University of Singapore (NUS), Singapore, Republic of Singapore.; Department of Clinical Sciences, Clinical Research Centre, Lund University, Malmö, Sweden.
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Źródło:
PLoS biology [PLoS Biol] 2020 Oct 19; Vol. 18 (10), pp. e3000903. Date of Electronic Publication: 2020 Oct 19 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Crossing Over, Genetic*
Meiosis*
Cyclin-Dependent Kinase 2/*metabolism
Animals ; Apoptosis ; Cell Cycle Checkpoints ; Cell Cycle Proteins/metabolism ; Chromosome Pairing ; DNA Repair ; Histones/metabolism ; Ligases/metabolism ; Male ; Meiotic Prophase I ; Metaphase ; Mice, Inbred C57BL ; Mice, Transgenic ; MutL Protein Homolog 1/metabolism ; Pachytene Stage ; Sex Chromosomes/genetics ; Spermatozoa/cytology ; Spermatozoa/metabolism ; Synaptonemal Complex/metabolism ; Telomere/metabolism
Czasopismo naukowe
Tytuł:
MLH1 focus mapping in the guinea fowl (Numida meleagris) give insights into the crossover landscapes in birds.
Autorzy:
Del Priore L; INBIOMED (CONICET-UBA), Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires, Argentina.
Pigozzi MI; INBIOMED (CONICET-UBA), Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires, Argentina.
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Źródło:
PloS one [PLoS One] 2020 Oct 05; Vol. 15 (10), pp. e0240245. Date of Electronic Publication: 2020 Oct 05 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
MutL Protein Homolog 1/*metabolism
Synaptonemal Complex/*metabolism
Animals ; Chickens ; Karyotype ; Oocytes ; Phylogeny
Czasopismo naukowe
Tytuł:
Targeted sequencing of genes associated with the mismatch repair pathway in patients with endometrial cancer.
Autorzy:
Singh AK; Department of Medical Genetics, St. Olavs Hospital, Trondheim, Norway.; Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, NTNU-Norwegian University of Science and Technology, Trondheim, Norway.
Talseth-Palmer B; Department of Medical Genetics, St. Olavs Hospital, Trondheim, Norway.; School of Biomedical Science and Pharmacy, Faculty of Health and Medicine, University of Newcastle and Hunter Medical Research Institute, Newcastle, Australia.; Department of Research and Development, Møre og Romsdal Hospital Trust, Molde, Norway.
McPhillips M; NSW Health Pathology, Molecular Medicine, John Hunter Hospital, Newcastle, NSW, Australia.
Lavik LAS; Department of Medical Genetics, St. Olavs Hospital, Trondheim, Norway.
Xavier A; School of Biomedical Science and Pharmacy, Faculty of Health and Medicine, University of Newcastle and Hunter Medical Research Institute, Newcastle, Australia.
Drabløs F; Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, NTNU-Norwegian University of Science and Technology, Trondheim, Norway.
Sjursen W; Department of Medical Genetics, St. Olavs Hospital, Trondheim, Norway.; Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, NTNU-Norwegian University of Science and Technology, Trondheim, Norway.
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Źródło:
PloS one [PLoS One] 2020 Jul 07; Vol. 15 (7), pp. e0235613. Date of Electronic Publication: 2020 Jul 07 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
DNA Mismatch Repair*
Endometrial Neoplasms/*pathology
Mismatch Repair Endonuclease PMS2/*genetics
MutL Protein Homolog 1/*genetics
MutS Homolog 2 Protein/*genetics
Colorectal Neoplasms, Hereditary Nonpolyposis/genetics ; Colorectal Neoplasms, Hereditary Nonpolyposis/pathology ; DNA Copy Number Variations ; DNA, Neoplasm/blood ; DNA, Neoplasm/chemistry ; DNA, Neoplasm/metabolism ; Endometrial Neoplasms/genetics ; Exons ; Female ; High-Throughput Nucleotide Sequencing ; Humans ; Introns ; Risk Factors ; Untranslated Regions/genetics
Czasopismo naukowe
Tytuł:
Cost-effectiveness analysis of genetic diagnostic strategies for Lynch syndrome in Italy.
Autorzy:
Pastorino R; Department of Woman and Child Health and Public Health-Public Health Area, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italia.
Basile M; Università Cattolica del Sacro Cuore, Alta Scuola di Economia e Management dei Sistemi Sanitari (ALTEMS), Roma, Italia.
Tognetto A; Section of Hygiene, University Department of Life Sciences and Public Health, Università Cattolica del Sacro Cuore, Roma, Italia.
Di Marco M; Department of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy.
Grossi A; Section of Hygiene, University Department of Life Sciences and Public Health, Università Cattolica del Sacro Cuore, Roma, Italia.
Lucci-Cordisco E; Department of Laboratory and Infectious Sciences, Medical Genetics Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.; Dipartimento di Scienze della Vita e di Sanità Pubblica, Sezione di Medicina Genomica, Università Cattolica del Sacro Cuore, Rome, Italy.
Scaldaferri F; UOC Medicina Interna, Gastroenterologia e Malattie del Fegato, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
De Censi A; Medical Oncology Unit, Galliera Hospital, Genova, Italy.
Federici A; Direction of Prevention, Ministry of Health, Rome, Italy.
Villari P; Department of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy.
Genuardi M; Department of Laboratory and Infectious Sciences, Medical Genetics Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.; Dipartimento di Scienze della Vita e di Sanità Pubblica, Sezione di Medicina Genomica, Università Cattolica del Sacro Cuore, Rome, Italy.
Ricciardi W; Department of Woman and Child Health and Public Health-Public Health Area, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italia.; Section of Hygiene, University Department of Life Sciences and Public Health, Università Cattolica del Sacro Cuore, Roma, Italia.
Boccia S; Department of Woman and Child Health and Public Health-Public Health Area, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italia.; Section of Hygiene, University Department of Life Sciences and Public Health, Università Cattolica del Sacro Cuore, Roma, Italia.
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Źródło:
PloS one [PLoS One] 2020 Jul 01; Vol. 15 (7), pp. e0235038. Date of Electronic Publication: 2020 Jul 01 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Colorectal Neoplasms/*diagnosis
Colorectal Neoplasms, Hereditary Nonpolyposis/*diagnosis
Genetic Testing/*economics
Colorectal Neoplasms/economics ; Colorectal Neoplasms/epidemiology ; Colorectal Neoplasms/genetics ; Colorectal Neoplasms, Hereditary Nonpolyposis/economics ; Colorectal Neoplasms, Hereditary Nonpolyposis/epidemiology ; Colorectal Neoplasms, Hereditary Nonpolyposis/genetics ; Cost-Benefit Analysis ; DNA Mismatch Repair ; Genetic Testing/methods ; Humans ; Italy/epidemiology ; MutL Protein Homolog 1/genetics ; Pedigree ; Probability ; Quality-Adjusted Life Years
Czasopismo naukowe
Tytuł:
Yeast mismatch repair components are required for stable inheritance of gene silencing.
Autorzy:
Liu Q; Department of Chemistry and Molecular Biology, University of Gothenburg, Medicinaregatan, Goteborg, Sweden.
Zhu X; Institute of Biomedicine, University of Gothenburg, Goteborg, Sweden.
Lindström M; Department of Chemistry and Molecular Biology, University of Gothenburg, Medicinaregatan, Goteborg, Sweden.
Shi Y; Institute of Biomedicine, University of Gothenburg, Goteborg, Sweden.
Zheng J; Department of Chemistry and Molecular Biology, University of Gothenburg, Medicinaregatan, Goteborg, Sweden.; Department of Biology, Functional Biology, KU Leuven, Heverlee, Belgium.
Hao X; Department of Chemistry and Molecular Biology, University of Gothenburg, Medicinaregatan, Goteborg, Sweden.
Gustafsson CM; Institute of Biomedicine, University of Gothenburg, Goteborg, Sweden.
Liu B; Department of Chemistry and Molecular Biology, University of Gothenburg, Medicinaregatan, Goteborg, Sweden.; Center for Large-scale cell-based screening, Faculty of Science, University of Gothenburg, Medicinaregatan, Goteborg, Sweden.
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Źródło:
PLoS genetics [PLoS Genet] 2020 May 29; Vol. 16 (5), pp. e1008798. Date of Electronic Publication: 2020 May 29 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
MutL Protein Homolog 1/*genetics
MutL Proteins/*genetics
MutS Homolog 2 Protein/*genetics
Saccharomyces cerevisiae/*metabolism
Saccharomyces cerevisiae Proteins/*genetics
Acetylation ; DNA Mismatch Repair ; Epigenesis, Genetic ; Gene Silencing ; Genes, Mating Type, Fungal ; Heredity ; Histones/metabolism ; Saccharomyces cerevisiae/genetics ; Silent Information Regulator Proteins, Saccharomyces cerevisiae/metabolism ; Sirtuin 2/metabolism ; Telomere/genetics
Czasopismo naukowe
Tytuł:
Investigation on the hereditary basis of colorectal cancers in an African population with frequent early onset cases.
Autorzy:
Katsidzira L; Department of Medicine, College of Health Sciences, University of Zimbabwe, Harare, Zimbabwe.; MRC/UCT Research Unit for Genomic and Precision Medicine, Division of Human Genetics, Institute of Infectious Diseases and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Vorster A; MRC/UCT Research Unit for Genomic and Precision Medicine, Division of Human Genetics, Institute of Infectious Diseases and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.; Central Analytical Facility (CAF), DNA Sequencing Unit, Stellenbosch University, Stellenbosch, South Africa.
Gangaidzo IT; Department of Medicine, College of Health Sciences, University of Zimbabwe, Harare, Zimbabwe.
Makunike-Mutasa R; Department of Histopathology, College of Health Sciences, University of Zimbabwe, Harare, Zimbabwe.
Govender D; Division of Anatomical Pathology, Faculty of Health Sciences, University of Cape Town, and National Health Laboratory Service Groote Schuur hospital, Cape Town, South Africa.
Rusakaniko S; Department of Community Medicine, College of Health Sciences, University of Zimbabwe, Harare, Zimbabwe.
Thomson S; Division of Gastroenterology, Department of Medicine, University of Cape Town, Cape Town, Groote Schuur Hospital, Cape Town, South Africa.
Matenga JA; Department of Medicine, College of Health Sciences, University of Zimbabwe, Harare, Zimbabwe.
Ramesar R; MRC/UCT Research Unit for Genomic and Precision Medicine, Division of Human Genetics, Institute of Infectious Diseases and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
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Źródło:
PloS one [PLoS One] 2019 Oct 24; Vol. 14 (10), pp. e0224023. Date of Electronic Publication: 2019 Oct 24 (Print Publication: 2019).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Genetic Predisposition to Disease*
Germ-Line Mutation*
Black People/*genetics
Colorectal Neoplasms/*genetics
Epithelial Cell Adhesion Molecule/*genetics
MutL Protein Homolog 1/*genetics
MutS Homolog 2 Protein/*genetics
Adult ; Age of Onset ; Colorectal Neoplasms/epidemiology ; Cross-Sectional Studies ; Female ; Humans ; Incidence ; Male ; Microsatellite Instability ; Middle Aged ; Prognosis ; Prospective Studies ; Zimbabwe/epidemiology
Czasopismo naukowe
Tytuł:
RPL22L1 induction in colorectal cancer is associated with poor prognosis and 5-FU resistance.
Autorzy:
Rao S; Center for Translational Medicine, Department of Surgery, George Washington University, Washington, DC, United States of America.
Peri S; Blood Cell Development and Function Program, Fox Chase Cancer Center, Philadelphia, PA, United States of America.
Hoffmann J; Experimental Pharmacology & Oncology Berlin-Buch GMBH, Berlin-Buch, Germany.
Cai KQ; Cancer Biology Program, Fox Chase Cancer Center, Philadelphia, PA, United States of America.
Harris B; Blood Cell Development and Function Program, Fox Chase Cancer Center, Philadelphia, PA, United States of America.
Rhodes M; Blood Cell Development and Function Program, Fox Chase Cancer Center, Philadelphia, PA, United States of America.
Connolly DC; Molecular Therapeutics Program, Fox Chase Cancer Center, Philadelphia, PA, United States of America.
Testa JR; Cancer Biology Program, Fox Chase Cancer Center, Philadelphia, PA, United States of America.
Wiest DL; Blood Cell Development and Function Program, Fox Chase Cancer Center, Philadelphia, PA, United States of America.
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Źródło:
PloS one [PLoS One] 2019 Oct 03; Vol. 14 (10), pp. e0222392. Date of Electronic Publication: 2019 Oct 03 (Print Publication: 2019).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Drug Resistance, Neoplasm*
Colorectal Neoplasms/*drug therapy
Colorectal Neoplasms/*metabolism
Fluorouracil/*therapeutic use
RNA-Binding Proteins/*metabolism
Ribosomal Proteins/*metabolism
Animals ; Cell Proliferation ; Colorectal Neoplasms/pathology ; DNA Modification Methylases/metabolism ; DNA Repair Enzymes/metabolism ; Humans ; Mice ; MutL Protein Homolog 1/metabolism ; Prognosis ; Proto-Oncogene Proteins/metabolism ; Tumor Suppressor Proteins/metabolism
Czasopismo naukowe
Tytuł:
The prevalence and persistence of aberrant promoter DNA methylation in benzene-exposed Chinese workers.
Autorzy:
Ren J; Henan International Collaborative Laboratory for Health Effects and Intervention of Air Pollution, Medicine, School of Public Health, Xinxiang Medical University, Xinxiang, China.
Cui JP; Henan International Collaborative Laboratory for Health Effects and Intervention of Air Pollution, Medicine, School of Public Health, Xinxiang Medical University, Xinxiang, China.
Luo M; Henan International Collaborative Laboratory for Health Effects and Intervention of Air Pollution, Medicine, School of Public Health, Xinxiang Medical University, Xinxiang, China.
Liu H; Henan International Collaborative Laboratory for Health Effects and Intervention of Air Pollution, Medicine, School of Public Health, Xinxiang Medical University, Xinxiang, China.
Hao P; Xinxiang Center for Disease Control and Prevention, Xinxiang, China.
Wang X; Henan International Collaborative Laboratory for Health Effects and Intervention of Air Pollution, Medicine, School of Public Health, Xinxiang Medical University, Xinxiang, China.
Zhang GH; Henan International Collaborative Laboratory for Health Effects and Intervention of Air Pollution, Medicine, School of Public Health, Xinxiang Medical University, Xinxiang, China.
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Źródło:
PloS one [PLoS One] 2019 Aug 05; Vol. 14 (8), pp. e0220500. Date of Electronic Publication: 2019 Aug 05 (Print Publication: 2019).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Benzene/*adverse effects
DNA Methylation/*drug effects
Environmental Pollutants/*adverse effects
Occupational Exposure/*adverse effects
Promoter Regions, Genetic/*drug effects
Adolescent ; Adult ; Aged ; Cell Line ; Female ; Humans ; Long Interspersed Nucleotide Elements/drug effects ; Male ; Middle Aged ; MutL Protein Homolog 1/genetics ; O(6)-Methylguanine-DNA Methyltransferase/genetics ; Occupational Exposure/analysis ; Young Adult
Czasopismo naukowe

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