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Wyszukujesz frazę ""Mutation Accumulation"" wg kryterium: Temat


Tytuł :
Acquired genetic changes in human pluripotent stem cells: origins and consequences.
Autorzy :
Halliwell J; Centre for Stem Cell Biology, Department of Biomedical Science, The University of Sheffield, Sheffield, UK.
Barbaric I; Centre for Stem Cell Biology, Department of Biomedical Science, The University of Sheffield, Sheffield, UK. .
Andrews PW; Centre for Stem Cell Biology, Department of Biomedical Science, The University of Sheffield, Sheffield, UK. .
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Źródło :
Nature reviews. Molecular cell biology [Nat Rev Mol Cell Biol] 2020 Dec; Vol. 21 (12), pp. 715-728. Date of Electronic Publication: 2020 Sep 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Mutation Accumulation*
Clonal Evolution/*genetics
Pluripotent Stem Cells/*metabolism
Cell Culture Techniques/methods ; Cell Culture Techniques/standards ; Cell Differentiation/genetics ; Cell- and Tissue-Based Therapy/methods ; Cell- and Tissue-Based Therapy/trends ; Cells, Cultured ; Clonal Evolution/physiology ; Human Embryonic Stem Cells/physiology ; Humans ; Mutation/physiology ; Pluripotent Stem Cells/physiology
Czasopismo naukowe
Tytuł :
Metal exposure causes rDNA copy number to fluctuate in mutation accumulation lines of Daphnia pulex.
Autorzy :
Harvey EF; Department of Integrative Biology, University of Guelph, 50 Stone Road West, Guelph, ON, N1G 2W1, Canada.
Cristescu ME; Biology Department, McGill University, Stewart Biology Building, 1205 Dr Penfield Ave, Montreal, QC, H3A 1B1, Canada.
Dale J; Department of Integrative Biology, University of Guelph, 50 Stone Road West, Guelph, ON, N1G 2W1, Canada.
Hunter H; Department of Integrative Biology, University of Guelph, 50 Stone Road West, Guelph, ON, N1G 2W1, Canada.
Randall C; Department of Integrative Biology, University of Guelph, 50 Stone Road West, Guelph, ON, N1G 2W1, Canada.
Crease TJ; Department of Integrative Biology, University of Guelph, 50 Stone Road West, Guelph, ON, N1G 2W1, Canada. Electronic address: .
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Źródło :
Aquatic toxicology (Amsterdam, Netherlands) [Aquat Toxicol] 2020 Sep; Vol. 226, pp. 105556. Date of Electronic Publication: 2020 Jun 30.
Typ publikacji :
Journal Article
MeSH Terms :
Mutation Accumulation*
DNA Copy Number Variations/*drug effects
DNA, Ribosomal/*genetics
Daphnia/*drug effects
Metals, Heavy/*toxicity
Water Pollutants, Chemical/*toxicity
Animals ; Copper/toxicity ; Daphnia/genetics ; Nickel/toxicity ; RNA, Ribosomal, 18S/genetics ; Reproduction/drug effects ; Reproduction/genetics
Czasopismo naukowe
Tytuł :
Field Carcinogenesis in Cancer Evolution: What the Cell Is Going On?
Autorzy :
Sinjab A; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Han G; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Wang L; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Kadara H; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas .
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Źródło :
Cancer research [Cancer Res] 2020 Nov 15; Vol. 80 (22), pp. 4888-4891. Date of Electronic Publication: 2020 Oct 06.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Mutation Accumulation*
Single-Cell Analysis*/methods
Carcinogenesis/*genetics
Neoplasms/*genetics
Carcinogenesis/pathology ; Carcinogens/toxicity ; Cell Transformation, Neoplastic ; Genes, p53 ; Humans ; Neoplasms/pathology ; Neoplasms/prevention & control ; Precancerous Conditions/genetics ; Precancerous Conditions/pathology ; Tumor Microenvironment
Czasopismo naukowe
Tytuł :
Trends of mutation accumulation across global SARS-CoV-2 genomes: Implications for the evolution of the novel coronavirus.
Autorzy :
Roy C; College of Veterinary Medicine, Western University of Health Sciences, 309 East Second Street, Pomona, CA 91766, USA.
Mandal SM; Central Research Facility, Indian Institute of Technology Kharagpur, Kharagpur 721302, West Bengal, India.
Mondal SK; Central Research Facility, Indian Institute of Technology Kharagpur, Kharagpur 721302, West Bengal, India.
Mukherjee S; Department of Botany, Prasannadeb Women's College, Jalpaiguri, West Bengal, India.
Mapder T; Division of Clinical Pharmacology, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
Ghosh W; Department of Microbiology, Bose Institute, P-1/12 CIT Scheme VII M, Kolkata 700054, West Bengal, India. Electronic address: .
Chakraborty R; Department of Biotechnology, University of North Bengal, Raja Rammohanpur, Darjeeling 734013, West Bengal, India. Electronic address: .
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Źródło :
Genomics [Genomics] 2020 Nov; Vol. 112 (6), pp. 5331-5342. Date of Electronic Publication: 2020 Nov 05.
Typ publikacji :
Journal Article
MeSH Terms :
Evolution, Molecular*
Genome, Viral*
Mutation Accumulation*
SARS-CoV-2/*genetics
Asia ; Genomics/methods ; India ; Mutation Rate ; Mutation, Missense ; Phylogeny ; Spike Glycoprotein, Coronavirus/genetics ; Viral Proteins/genetics ; Viroporin Proteins/genetics
Czasopismo naukowe
Tytuł :
Intra-species differences in population size shape life history and genome evolution.
Autorzy :
Willemsen D; Max Planck Institute for Biology of Ageing, Cologne, Germany.
Cui R; Max Planck Institute for Biology of Ageing, Cologne, Germany.
Reichard M; Czech Academy of Sciences, Institute of Vertebrate Biology, Brno, Czech Republic.; Department of Botany and Zoology, Faculty of Science, Masaryk University, Brno, Czech Republic.
Valenzano DR; Max Planck Institute for Biology of Ageing, Cologne, Germany.; CECAD, University of Cologne, Cologne, Germany.
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Źródło :
ELife [Elife] 2020 Sep 01; Vol. 9. Date of Electronic Publication: 2020 Sep 01.
Typ publikacji :
Journal Article
MeSH Terms :
Evolution, Molecular*
Mutation Accumulation*
Population Density*
Longevity/*genetics
Aging/genetics ; Animals ; Biological Evolution ; Ecosystem ; Fundulidae ; Genome/genetics ; Models, Animal
Czasopismo naukowe
Tytuł :
Demographic history shaped geographical patterns of deleterious mutation load in a broadly distributed Pacific Salmon.
Autorzy :
Rougemont Q; Département de Biologie, Institut de Biologie Intégrative et des Systèmes (IBIS), Université Laval, Québec, Québec, Canada.
Moore JS; Département de Biologie, Institut de Biologie Intégrative et des Systèmes (IBIS), Université Laval, Québec, Québec, Canada.
Leroy T; ISEM, Univ. Montpellier, CNRS, EPHE, IRD, Montpellier, France.; Department of Botany & Biodiversity Research, University of Vienna, Vienna, Austria.
Normandeau E; Département de Biologie, Institut de Biologie Intégrative et des Systèmes (IBIS), Université Laval, Québec, Québec, Canada.
Rondeau EB; Centre for Biomedical Research, University of Victoria, Victoria, BC, Canada.; Department of Biology, University of Victoria, Victoria, BC, Canada.
Withler RE; Department of Fisheries and Ocean, Pacific Biological Station, Nanaimo, British Columbia, Canada.
Van Doornik DM; National Oceanic and Atmospheric Administration, National Marine Fisheries Service, Northwest Fisheries Science Center, Manchester Research Station, Port Orchard, Washington, United States of America.
Crane PA; Conservation Genetics Laboratory, U.S. Fish and Wildlife Service, Anchorage, Alaska, United States of America.
Naish KA; School of Aquatic and Fishery Sciences, University of Washington, Seattle, WA, United States of America.
Garza JC; Fisheries Ecology Division, Southwest Fisheries Science Center, National Marine Fisheries Service and Institute of Marine Sciences, University of California-Santa Cruz, Santa Cruz, California, United States of America.
Beacham TD; Department of Fisheries and Ocean, Pacific Biological Station, Nanaimo, British Columbia, Canada.
Koop BF; Centre for Biomedical Research, University of Victoria, Victoria, BC, Canada.; Department of Biology, University of Victoria, Victoria, BC, Canada.
Bernatchez L; Département de Biologie, Institut de Biologie Intégrative et des Systèmes (IBIS), Université Laval, Québec, Québec, Canada.
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Źródło :
PLoS genetics [PLoS Genet] 2020 Aug 26; Vol. 16 (8), pp. e1008348. Date of Electronic Publication: 2020 Aug 26 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Animal Distribution*
Mutation Accumulation*
Oncorhynchus kisutch/*genetics
Animals ; Evolution, Molecular ; Models, Genetic
Czasopismo naukowe
Tytuł :
mtDNA Mutation Accumulation in Muscle Is Not a Major Cause of Fiber Loss. Reply to "Comment on: Mitochondrial Mechanisms of Neuromuscular Junction Degeneration with Aging. Cells 2020, 9 , 197".
Autorzy :
Hepple RT; Department of Physical Therapy, University of Florida, Gainesville, FL 32610, USA.
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Źródło :
Cells [Cells] 2020 Aug 01; Vol. 9 (8). Date of Electronic Publication: 2020 Aug 01.
Typ publikacji :
Letter; Comment
MeSH Terms :
DNA, Mitochondrial*/genetics
Mutation Accumulation*
Mitochondria/genetics ; Neuromuscular Junction/metabolism
Opinia redakcyjna
Tytuł :
Mutation accumulation and developmental lineages in normal and Down syndrome human fetal haematopoiesis.
Autorzy :
Hasaart KAL; Princess Máxima Center for Pediatric Oncology and Oncode Institute, Heidelberglaan 25, 3584CS, Utrecht, The Netherlands.
Manders F; Princess Máxima Center for Pediatric Oncology and Oncode Institute, Heidelberglaan 25, 3584CS, Utrecht, The Netherlands.
van der Hoorn ML; Leiden University Medical Center, 2333 ZC, Leiden, The Netherlands.
Verheul M; Princess Máxima Center for Pediatric Oncology and Oncode Institute, Heidelberglaan 25, 3584CS, Utrecht, The Netherlands.
Poplonski T; Princess Máxima Center for Pediatric Oncology, Heidelberglaan 25, 3584CS, Utrecht, The Netherlands.
Kuijk E; Center for Molecular Medicine, University Medical Center Utrecht and Oncode Institute, Universiteitsweg 100, 3584 CG, Utrecht, The Netherlands.
de Sousa Lopes SMC; Department of Anatomy and Embryology, Leiden University Medical Center, 2333 ZC, Leiden, The Netherlands.
van Boxtel R; Princess Máxima Center for Pediatric Oncology and Oncode Institute, Heidelberglaan 25, 3584CS, Utrecht, The Netherlands. .
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Źródło :
Scientific reports [Sci Rep] 2020 Jul 31; Vol. 10 (1), pp. 12991. Date of Electronic Publication: 2020 Jul 31.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Down Syndrome*/embryology
Down Syndrome*/genetics
Down Syndrome*/pathology
Mutation Accumulation*
Cell Lineage/*genetics
Fetus/*metabolism
Hematopoiesis/*genetics
Hematopoietic Stem Cells/*metabolism
Female ; Fetus/pathology ; Hematopoietic Stem Cells/pathology ; Humans ; Leukemia/embryology ; Leukemia/genetics ; Leukemia/pathology ; Male ; Whole Genome Sequencing
Czasopismo naukowe
Tytuł :
Considering mutational meltdown as a potential SARS-CoV-2 treatment strategy.
Autorzy :
Jensen JD; School of Life Sciences, Arizona State University, Tempe, AZ, USA. .
Lynch M; School of Life Sciences, Arizona State University, Tempe, AZ, USA.
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Źródło :
Heredity [Heredity (Edinb)] 2020 May; Vol. 124 (5), pp. 619-620. Date of Electronic Publication: 2020 Apr 06.
Typ publikacji :
Journal Article
MeSH Terms :
Mutation*
Mutation Accumulation*
Antiviral Agents/*therapeutic use
Betacoronavirus/*genetics
Coronavirus Infections/*drug therapy
Pneumonia, Viral/*drug therapy
Amides/pharmacology ; Amides/therapeutic use ; Antiviral Agents/pharmacology ; Betacoronavirus/drug effects ; COVID-19 ; Coronavirus Infections/virology ; Humans ; Models, Genetic ; Pandemics ; Pneumonia, Viral/virology ; Pyrazines/pharmacology ; Pyrazines/therapeutic use ; SARS-CoV-2
SCR Protocol :
COVID-19 drug treatment
Czasopismo naukowe
Tytuł :
Burden of tumor mutations, neoepitopes, and other variants are weak predictors of cancer immunotherapy response and overall survival.
Autorzy :
Wood MA; Computational Biology Program, Oregon Health & Science University, Portland, USA.; Portland VA Research Foundation, Portland, USA.
Weeder BR; Computational Biology Program, Oregon Health & Science University, Portland, USA.; Department of Biomedical Engineering, Oregon Health & Science University, Portland, USA.
David JK; Computational Biology Program, Oregon Health & Science University, Portland, USA.; Department of Biomedical Engineering, Oregon Health & Science University, Portland, USA.
Nellore A; Computational Biology Program, Oregon Health & Science University, Portland, USA.; Department of Biomedical Engineering, Oregon Health & Science University, Portland, USA.; Department of Surgery, Oregon Health & Science University, Portland, USA.
Thompson RF; Computational Biology Program, Oregon Health & Science University, Portland, USA. .; Portland VA Research Foundation, Portland, USA. .; Department of Biomedical Engineering, Oregon Health & Science University, Portland, USA. .; Department of Radiation Medicine, Oregon Health & Science University, Portland, USA. .; Department of Medical Informatics & Clinical Epidemiology, Oregon Health & Science University, Portland, USA. .; VA Portland Healthcare System, Division of Hospital and Specialty Medicine, Portland, USA. .
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Źródło :
Genome medicine [Genome Med] 2020 Mar 30; Vol. 12 (1), pp. 33. Date of Electronic Publication: 2020 Mar 30.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Mutation Accumulation*
Carcinoma, Non-Small-Cell Lung/*genetics
Immune Checkpoint Inhibitors/*therapeutic use
Lung Neoplasms/*genetics
Melanoma/*genetics
Antigens, Neoplasm/genetics ; Antigens, Neoplasm/immunology ; Biomarkers, Tumor/genetics ; Biomarkers, Tumor/immunology ; Carcinoma, Non-Small-Cell Lung/drug therapy ; Epitopes/genetics ; Epitopes/immunology ; Humans ; Lung Neoplasms/drug therapy ; Melanoma/drug therapy
Czasopismo naukowe
Tytuł :
A compartment size-dependent selective threshold limits mutation accumulation in hierarchical tissues.
Autorzy :
Grajzel D; MTA-ELTE 'Lendület' Evolutionary Genomics Research Group, H-1117 Budapest, Hungary.; Department of Biological Physics, Eötvös Loránd University, H-1117 Budapest, Hungary.
Derényi I; Department of Biological Physics, Eötvös Loránd University, H-1117 Budapest, Hungary.; MTA-ELTE Statistical and Biological Physics Research Group, Hungarian Academy of Sciences, H-1117 Budapest, Hungary.
Szöllősi GJ; MTA-ELTE 'Lendület' Evolutionary Genomics Research Group, H-1117 Budapest, Hungary; .; Department of Biological Physics, Eötvös Loránd University, H-1117 Budapest, Hungary.; Evolutionary Systems Research Group, Centre for Ecological Research, Hungarian Academy of Sciences, 8237 Tihany, Hungary.
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Jan 21; Vol. 117 (3), pp. 1606-1611. Date of Electronic Publication: 2020 Jan 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Models, Genetic*
Mutation Accumulation*
Genes, Neoplasm/*genetics
Neoplasms/*genetics
Cell Differentiation/genetics ; Cell Division ; Clonal Evolution/genetics ; Computer Simulation ; Cytoprotection/genetics ; Humans ; Mutation
Czasopismo naukowe
Tytuł :
Beyond tumor mutational burden: potential and limitations in using exosomes to predict response to immunotherapy.
Autorzy :
Crow J; Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, KS, USA.
Samuel G; Division of Hematology Oncology, and Bone Marrow Transplant, The Children's Mercy Hospital, Kansas City, MO, USA.
Godwin AK; Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, KS, USA.; University of Kansas Cancer Center, University of Kansas Medical Center, Kansas City, KS, USA.
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Źródło :
Expert review of molecular diagnostics [Expert Rev Mol Diagn] 2019 Dec; Vol. 19 (12), pp. 1079-1088. Date of Electronic Publication: 2019 Nov 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Immunotherapy*
Mutation Accumulation*
Biomarkers, Tumor/*genetics
Exosomes/*genetics
Neoplasms/*genetics
Biomarkers, Tumor/metabolism ; Exosomes/metabolism ; Genomics/methods ; Humans ; Neoplasms/therapy
Czasopismo naukowe
Tytuł :
Large, three-generation human families reveal post-zygotic mosaicism and variability in germline mutation accumulation.
Autorzy :
Sasani TA; Department of Human Genetics, University of Utah, Salt Lake City, United States.
Pedersen BS; Department of Human Genetics, University of Utah, Salt Lake City, United States.
Gao Z; Howard Hughes Medical Institute and Department of Genetics, Stanford University, Stanford, United States.
Baird L; Department of Human Genetics, University of Utah, Salt Lake City, United States.
Przeworski M; Department of Biological Sciences, Columbia University, New York City, United States.; Department of Systems Biology, Columbia University, New York City, United States.
Jorde LB; Department of Human Genetics, University of Utah, Salt Lake City, United States.; USTAR Center for Genetic Discovery, University of Utah, Salt Lake City, United States.
Quinlan AR; Department of Human Genetics, University of Utah, Salt Lake City, United States.; USTAR Center for Genetic Discovery, University of Utah, Salt Lake City, United States.; Department of Biomedical Informatics, University of Utah, Salt Lake City, United States.
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Źródło :
ELife [Elife] 2019 Sep 24; Vol. 8. Date of Electronic Publication: 2019 Sep 24.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Family Health*
Germ-Line Mutation*
Mosaicism*
Mutation Accumulation*
Humans ; Mutation Rate ; Sequence Analysis, DNA ; Utah
Czasopismo naukowe
Tytuł :
A little bit of sex prevents mutation accumulation even in apomictic polyploid plants.
Autorzy :
Hodač L; Department of Systematics, Biodiversity and Evolution of Plants (with Herbarium), University of Goettingen, Goettingen, Germany.
Klatt S; Department of Systematics, Biodiversity and Evolution of Plants (with Herbarium), University of Goettingen, Goettingen, Germany.
Hojsgaard D; Department of Systematics, Biodiversity and Evolution of Plants (with Herbarium), University of Goettingen, Goettingen, Germany.
Sharbel TF; Global Institute for Food Security, University of Saskatchewan, Saskatoon, Canada.
Hörandl E; Department of Systematics, Biodiversity and Evolution of Plants (with Herbarium), University of Goettingen, Goettingen, Germany. .
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Źródło :
BMC evolutionary biology [BMC Evol Biol] 2019 Aug 14; Vol. 19 (1), pp. 170. Date of Electronic Publication: 2019 Aug 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Mutation Accumulation*
Recombination, Genetic*
Ranunculus/*genetics
DNA, Plant/analysis ; DNA, Plant/genetics ; Microsatellite Repeats ; Mutation Rate ; Ovule ; Polyploidy ; Ranunculus/growth & development ; Ranunculus/physiology ; Reproduction, Asexual
Czasopismo naukowe
Tytuł :
Molecular footprint of Medawar's mutation accumulation process in mammalian aging.
Autorzy :
Turan ZG; Department of Biological Sciences, Middle East Technical University, Ankara, Turkey.
Parvizi P; Department of Biological Sciences, Middle East Technical University, Ankara, Turkey.; Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK.
Dönertaş HM; European Molecular Biology Laboratory, European Bioinformatics Institute EMBL-EBI, Wellcome Trust Genome Campus, Cambridge, UK.
Tung J; Department of Evolutionary Anthropology, Duke University, Durham, North Carolina.; Department of Biology, Duke University, Durham, North Carolina.; Duke Population Research Institute, Duke University, Durham, North Carolina.
Khaitovich P; Center for Neurobiology and Brain Restoration, Skolkovo Institute of Science and Technology, Moscow, Russia.; CAS Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China.
Somel M; Department of Biological Sciences, Middle East Technical University, Ankara, Turkey.
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Źródło :
Aging cell [Aging Cell] 2019 Aug; Vol. 18 (4), pp. e12965. Date of Electronic Publication: 2019 May 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Evolution, Molecular*
Mutation Accumulation*
Selection, Genetic*
Transcriptome*
Aging/*genetics
Alleles ; Animals ; Databases, Genetic ; Genetic Drift ; Humans ; Macaca/genetics ; Mice ; Phenotype ; Rats ; Up-Regulation/genetics
Czasopismo naukowe
Tytuł :
Mutational Landscape of Spontaneous Base Substitutions and Small Indels in Experimental Caenorhabditis elegans Populations of Differing Size.
Autorzy :
Konrad A; Department of Veterinary Integrative Biosciences, Texas A&M University, College Station, Texas 77845.
Brady MJ; Department of Veterinary Integrative Biosciences, Texas A&M University, College Station, Texas 77845.
Bergthorsson U; Department of Veterinary Integrative Biosciences, Texas A&M University, College Station, Texas 77845.
Katju V; Department of Veterinary Integrative Biosciences, Texas A&M University, College Station, Texas 77845 .
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Źródło :
Genetics [Genetics] 2019 Jul; Vol. 212 (3), pp. 837-854. Date of Electronic Publication: 2019 May 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
INDEL Mutation*
Mutation Accumulation*
Mutation Rate*
Animals ; Caenorhabditis elegans ; Genetic Drift ; Polymorphism, Single Nucleotide ; Selection, Genetic
Czasopismo naukowe
Tytuł :
Deleterious Mutation Accumulation in Arabidopsis thaliana Pollen Genes: A Role for a Recent Relaxation of Selection.
Autorzy :
Harrison MC
Mallon EB
Twell D
Hammond RL
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Źródło :
Genome biology and evolution [Genome Biol Evol] 2019 Jul 01; Vol. 11 (7), pp. 1939-1951.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Mutation Accumulation*
Arabidopsis/*genetics
Pollen/*metabolism
Arabidopsis/physiology ; Diploidy ; Gene Expression Regulation, Plant/genetics ; Gene Expression Regulation, Plant/physiology ; Genes, Plant/genetics ; Genes, Plant/physiology ; Haploidy ; Ploidies ; Pollen/genetics ; Selection, Genetic/genetics
Czasopismo naukowe
Tytuł :
Inferring the distribution of fitness effects of spontaneous mutations in Chlamydomonas reinhardtii.
Autorzy :
Böndel KB; Institute of Evolutionary Biology, Ashworth Laboratories, University of Edinburgh, Edinburgh, United Kingdom.
Kraemer SA; Institute of Evolutionary Biology, Ashworth Laboratories, University of Edinburgh, Edinburgh, United Kingdom.; Biology Department, Concordia University, Montreal, Quebec, Canada.
Samuels T; Institute of Evolutionary Biology, Ashworth Laboratories, University of Edinburgh, Edinburgh, United Kingdom.
McClean D; Institute of Immunology and Infection Research, Ashworth Laboratories, University of Edinburgh, Edinburgh, United Kingdom.
Lachapelle J; Department of Biology, William G. Davis Building, University of Toronto, Mississauga, Canada.
Ness RW; Department of Biology, William G. Davis Building, University of Toronto, Mississauga, Canada.
Colegrave N; Institute of Evolutionary Biology, Ashworth Laboratories, University of Edinburgh, Edinburgh, United Kingdom.
Keightley PD; Institute of Evolutionary Biology, Ashworth Laboratories, University of Edinburgh, Edinburgh, United Kingdom.
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Źródło :
PLoS biology [PLoS Biol] 2019 Jun 26; Vol. 17 (6), pp. e3000192. Date of Electronic Publication: 2019 Jun 26 (Print Publication: 2019).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Mutation Accumulation*
Chlamydomonas reinhardtii/*genetics
DNA Mutational Analysis/*methods
Genetic Fitness/*genetics
Bayes Theorem ; Biological Evolution ; Evolution, Molecular ; Genetic Variation ; Genotype ; Models, Genetic ; Mutagenesis ; Mutation/genetics ; Mutation Rate ; Selection, Genetic/genetics
Czasopismo naukowe
Tytuł :
Yeast Spontaneous Mutation Rate and Spectrum Vary with Environment.
Autorzy :
Liu H; Department of Ecology and Evolutionary Biology, University of Michigan, Ann Arbor, MI 48109, USA.
Zhang J; Department of Ecology and Evolutionary Biology, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address: .
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Źródło :
Current biology : CB [Curr Biol] 2019 May 20; Vol. 29 (10), pp. 1584-1591.e3. Date of Electronic Publication: 2019 May 02.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Mutation Accumulation*
Mutation Rate*
Saccharomyces cerevisiae/*genetics
Environment ; Mutagenesis ; Selection, Genetic
Czasopismo naukowe
Tytuł :
Chaperonin overproduction and metabolic erosion caused by mutation accumulation in Escherichia coli.
Autorzy :
Aguilar-Rodríguez J; Department of Evolutionary Biology and Environmental Studies, University of Zurich, Zurich, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, Switzerland.
Fares MA; Instituto de Biología Molecular y Celular de Plantas (CSIC-UPV), Valencia, Spain.; Department of Genetics, Smurfit Institute of Genetics, University of Dublin, Trinity College Dublin, Dublin, Ireland.
Wagner A; Department of Evolutionary Biology and Environmental Studies, University of Zurich, Zurich, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, Switzerland.; The Santa Fe Institute, Santa Fe, New Mexico, USA.
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Źródło :
FEMS microbiology letters [FEMS Microbiol Lett] 2019 May 01; Vol. 366 (10).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Mutation Accumulation*
Phenotype*
Symbiosis*
Chaperonin 60/*genetics
Escherichia coli/*genetics
Escherichia coli/*metabolism
Carbon/metabolism ; Chaperonin 60/metabolism ; Directed Molecular Evolution ; Genome, Bacterial
Czasopismo naukowe

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