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Wyszukujesz frazę ""Myeloid-Derived Suppressor Cells"" wg kryterium: Temat


Tytuł:
Carbon Ion Irradiation Activates Anti-Cancer Immunity.
Autorzy:
Sudo M; Department of Gastroenterological Surgery, Hyogo Medical University, Nishinomiya 663-8501, Japan.
Tsutsui H; Department of Gastroenterological Surgery, Hyogo Medical University, Nishinomiya 663-8501, Japan.
Fujimoto J; Department of Gastroenterological Surgery, Hyogo Medical University, Nishinomiya 663-8501, Japan.; Osaka Heavy Ion Therapy Center, Osaka 540-0008, Japan.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 29; Vol. 25 (5). Date of Electronic Publication: 2024 Feb 29.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Neoplasms*/pathology
Myeloid-Derived Suppressor Cells*
Heavy Ion Radiotherapy*
Humans ; T-Lymphocytes, Regulatory ; DNA ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
Pivotal role of myeloid-derived suppressor cells in infection-related tumor growth.
Autorzy:
Ito N; Department of Surgery, National Defense Medical College, Tokorozawa, Japan.
Tsujimoto H; Department of Surgery, National Defense Medical College, Tokorozawa, Japan.
Miyazaki H; Division of Biomedical Engineering, Research Institute, National Defense Medical College, Tokorozawa, Japan.
Takahata R; Department of Surgery, National Defense Medical College, Tokorozawa, Japan.
Ueno H; Department of Surgery, National Defense Medical College, Tokorozawa, Japan.
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Źródło:
Cancer medicine [Cancer Med] 2024 Feb; Vol. 13 (4), pp. e6917.
Typ publikacji:
Journal Article
MeSH Terms:
Myeloid-Derived Suppressor Cells*
Neoplasms*
Humans ; Animals ; Mice ; B7-H1 Antigen
Czasopismo naukowe
Tytuł:
Mesenchymal Stem/Stromal Cells Induce Myeloid-Derived Suppressor Cells in the Bone Marrow via the Activation of the c-Jun N-Terminal Kinase Signaling Pathway.
Autorzy:
Lee HJ; Laboratory of Ocular Regenerative Medicine and Immunology, Biomedical Research Institute, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, Seoul 03080, Republic of Korea.
Oh JY; Laboratory of Ocular Regenerative Medicine and Immunology, Biomedical Research Institute, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, Seoul 03080, Republic of Korea.; Department of Ophthalmology, Seoul National University College of Medicine, 103 Daehak-ro, Jongno-gu, Seoul 03080, Republic of Korea.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 17; Vol. 25 (2). Date of Electronic Publication: 2024 Jan 17.
Typ publikacji:
Journal Article
MeSH Terms:
Myeloid-Derived Suppressor Cells*
Mesenchymal Stem Cells*
JNK Mitogen-Activated Protein Kinases ; Bone Marrow ; Interleukin-10 ; Signal Transduction
Czasopismo naukowe
Tytuł:
Bladder-cancer-derived exosomal circRNA_0013936 promotes suppressive immunity by up-regulating fatty acid transporter protein 2 and down-regulating receptor-interacting protein kinase 3 in PMN-MDSCs.
Autorzy:
Shi X; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.
Pang S; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.
Zhou J; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.
Yan G; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.
Gao R; Southern Medical University, Guangzhou, China.
Wu H; Southern Medical University, Guangzhou, China.
Wang Z; Southern Medical University, Guangzhou, China.
Wei Y; Southern Medical University, Guangzhou, China.
Liu X; Southern Medical University, Guangzhou, China.
Tan W; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China. .
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Źródło:
Molecular cancer [Mol Cancer] 2024 Mar 09; Vol. 23 (1), pp. 52. Date of Electronic Publication: 2024 Mar 09.
Typ publikacji:
Journal Article
MeSH Terms:
Myeloid-Derived Suppressor Cells*/metabolism
Urinary Bladder Neoplasms*/pathology
MicroRNAs*/genetics
MicroRNAs*/metabolism
Humans ; RNA, Circular/genetics ; RNA, Circular/metabolism ; Fatty Acids/metabolism ; CD8-Positive T-Lymphocytes/metabolism ; Urinary Bladder/metabolism ; Protein Kinases/metabolism
Czasopismo naukowe
Tytuł:
Myeloid-Derived Suppressor Cells: Therapeutic Target for Gastrointestinal Cancers.
Autorzy:
Arshad J; University of Arizona Cancer Center, GI Medical Oncology, Tucson, AZ 85724, USA.
Rao A; Banner University Medical Center-University of Arizona, Tucson, AZ 85719, USA.
Repp ML; College of Medicine, University of Arizona, Tucson, AZ 85719, USA.
Rao R; University Hospitals Cleveland Medical Center, Case Western Reserve School of Medicine, Cleveland, OH 44106, USA.
Wu C; Banner University Medical Center-University of Arizona, Tucson, AZ 85719, USA.
Merchant JL; Division of Gastroenterology and Hepatology, Department of Medicine, University of Arizona College of Medicine, Tucson, AZ 85724, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Mar 04; Vol. 25 (5). Date of Electronic Publication: 2024 Mar 04.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Myeloid-Derived Suppressor Cells*/metabolism
Gastrointestinal Neoplasms*/metabolism
Humans ; Myeloid Cells ; Immunotherapy ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
FFAR2 expressing myeloid-derived suppressor cells drive cancer immunoevasion.
Autorzy:
Zhao Z; Shanghai Frontiers Science Center of Genome Editing and Cell Therapy, Shanghai Key Laboratory of Regulatory Biology and School of Life Sciences, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, 500 Dongchuan Road, Shanghai, 200241, China.
Qin J; Shanghai Frontiers Science Center of Genome Editing and Cell Therapy, Shanghai Key Laboratory of Regulatory Biology and School of Life Sciences, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, 500 Dongchuan Road, Shanghai, 200241, China.
Qian Y; Shanghai Frontiers Science Center of Genome Editing and Cell Therapy, Shanghai Key Laboratory of Regulatory Biology and School of Life Sciences, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, 500 Dongchuan Road, Shanghai, 200241, China.
Huang C; Fujian Provincial Hospital, Fuzhou, China.
Liu X; Shanghai Frontiers Science Center of Genome Editing and Cell Therapy, Shanghai Key Laboratory of Regulatory Biology and School of Life Sciences, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, 500 Dongchuan Road, Shanghai, 200241, China.
Wang N; Huzhou Central Hospital, Affiliated Hospital of Zhejiang University, Zhejiang, China.
Li L; Huzhou Central Hospital, Affiliated Hospital of Zhejiang University, Zhejiang, China.
Chao Y; Shanghai Frontiers Science Center of Genome Editing and Cell Therapy, Shanghai Key Laboratory of Regulatory Biology and School of Life Sciences, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, 500 Dongchuan Road, Shanghai, 200241, China.
Tan B; BRL Medicine Inc., Shanghai, China.
Zhang N; BRL Medicine Inc., Shanghai, China.
Qian M; Shanghai Frontiers Science Center of Genome Editing and Cell Therapy, Shanghai Key Laboratory of Regulatory Biology and School of Life Sciences, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, 500 Dongchuan Road, Shanghai, 200241, China.
Li D; Shanghai Frontiers Science Center of Genome Editing and Cell Therapy, Shanghai Key Laboratory of Regulatory Biology and School of Life Sciences, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, 500 Dongchuan Road, Shanghai, 200241, China.
Liu M; Shanghai Frontiers Science Center of Genome Editing and Cell Therapy, Shanghai Key Laboratory of Regulatory Biology and School of Life Sciences, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, 500 Dongchuan Road, Shanghai, 200241, China.
Du B; Shanghai Frontiers Science Center of Genome Editing and Cell Therapy, Shanghai Key Laboratory of Regulatory Biology and School of Life Sciences, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, 500 Dongchuan Road, Shanghai, 200241, China. .
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Źródło:
Journal of hematology & oncology [J Hematol Oncol] 2024 Feb 24; Vol. 17 (1), pp. 9. Date of Electronic Publication: 2024 Feb 24.
Typ publikacji:
Journal Article
MeSH Terms:
Myeloid-Derived Suppressor Cells*
Neoplasms*
Adenocarcinoma of Lung*/metabolism
Humans ; Mice ; Animals ; Calcium/metabolism ; Peroxisome Proliferator-Activated Receptors/metabolism ; Arginine/metabolism ; Acetates/metabolism ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
From glioma gloom to immune bloom: unveiling novel immunotherapeutic paradigms-a review.
Autorzy:
Regmi M; Department of Neurosurgery, Peking University Third Hospital, Peking University, Beijing, 100191, China.; Center for Precision Neurosurgery and Oncology of Peking University Health Science Center, Peking University, Beijing, 100191, China.; Peking University Health Science Center, Beijing, 100191, China.; Henan Academy of Innovations in Medical Science (AIMS), Zhengzhou, 450003, China.
Wang Y; Department of Neurosurgery, Peking University Third Hospital, Peking University, Beijing, 100191, China.; Center for Precision Neurosurgery and Oncology of Peking University Health Science Center, Peking University, Beijing, 100191, China.
Liu W; Department of Neurosurgery, Peking University Third Hospital, Peking University, Beijing, 100191, China.; Center for Precision Neurosurgery and Oncology of Peking University Health Science Center, Peking University, Beijing, 100191, China.; Peking University Health Science Center, Beijing, 100191, China.
Dai Y; Department of Neurosurgery, Peking University Third Hospital, Peking University, Beijing, 100191, China.; Center for Precision Neurosurgery and Oncology of Peking University Health Science Center, Peking University, Beijing, 100191, China.; Peking University Health Science Center, Beijing, 100191, China.
Liu S; Department of Neurosurgery, Peking University Third Hospital, Peking University, Beijing, 100191, China.; Center for Precision Neurosurgery and Oncology of Peking University Health Science Center, Peking University, Beijing, 100191, China.; Peking University Health Science Center, Beijing, 100191, China.
Ma K; Peking University Health Science Center, Beijing, 100191, China.
Lin G; Department of Neurosurgery, Peking University Third Hospital, Peking University, Beijing, 100191, China.; Center for Precision Neurosurgery and Oncology of Peking University Health Science Center, Peking University, Beijing, 100191, China.
Yang J; Department of Neurosurgery, Peking University Third Hospital, Peking University, Beijing, 100191, China.; Center for Precision Neurosurgery and Oncology of Peking University Health Science Center, Peking University, Beijing, 100191, China.
Liu H; Henan Academy of Innovations in Medical Science (AIMS), Zhengzhou, 450003, China.; National Engineering Research Center for Ophthalmology, Beijing, 100730, China.; Engineering Research Center of Ophthalmic Equipment and Materials, Ministry of Education, Beijing, 100730, China.; Beijing Key Laboratory of Ophthalmology and Visual Sciences, Beijing, 100730, China.
Wu J; Henan Academy of Innovations in Medical Science (AIMS), Zhengzhou, 450003, China. .; National Engineering Research Center for Ophthalmology, Beijing, 100730, China. .; Engineering Research Center of Ophthalmic Equipment and Materials, Ministry of Education, Beijing, 100730, China. .; Beijing Key Laboratory of Ophthalmology and Visual Sciences, Beijing, 100730, China. .
Yang C; Department of Neurosurgery, Peking University Third Hospital, Peking University, Beijing, 100191, China. .; Center for Precision Neurosurgery and Oncology of Peking University Health Science Center, Peking University, Beijing, 100191, China. .; Henan Academy of Innovations in Medical Science (AIMS), Zhengzhou, 450003, China. .
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Źródło:
Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2024 Feb 12; Vol. 43 (1), pp. 47. Date of Electronic Publication: 2024 Feb 12.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Glioma*/pathology
Glioblastoma*/pathology
Myeloid-Derived Suppressor Cells*
Brain Neoplasms*/drug therapy
Humans ; Immunotherapy ; Immunomodulation ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
Myeloid-Derived Suppressor-like Cells as a Prognostic Marker in Critically Ill Patients: Insights from Experimental Endotoxemia and Intensive Care Patients.
Autorzy:
Schrijver IT; Infectious Diseases Service, Department of Medicine, Lausanne University Hospital and University of Lausanne, 1011 Lausanne, Switzerland.
Herderschee J; Infectious Diseases Service, Department of Medicine, Lausanne University Hospital and University of Lausanne, 1011 Lausanne, Switzerland.
Théroude C; Infectious Diseases Service, Department of Medicine, Lausanne University Hospital and University of Lausanne, 1011 Lausanne, Switzerland.
Kritikos A; Infectious Diseases Service, Department of Medicine, Lausanne University Hospital and University of Lausanne, 1011 Lausanne, Switzerland.
Leijte G; Radboud Center for Infectious Diseases, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.; Department of Intensive Care Medicine, Radboud University Medical Center, 6525 EP Nijmegen, The Netherlands.
Le Roy D; Infectious Diseases Service, Department of Medicine, Lausanne University Hospital and University of Lausanne, 1011 Lausanne, Switzerland.
Brochut M; Infectious Diseases Service, Department of Medicine, Lausanne University Hospital and University of Lausanne, 1011 Lausanne, Switzerland.
Chiche JD; Service of Adult Intensive Care Medicine, Lausanne University Hospital and University of Lausanne, 1011 Lausanne, Switzerland.
Perreau M; Service of Immunology and Allergy, Department of Medicine, Lausanne University Hospital and University of Lausanne, 1010 Lausanne, Switzerland.
Pantaleo G; Service of Immunology and Allergy, Department of Medicine, Lausanne University Hospital and University of Lausanne, 1010 Lausanne, Switzerland.
Guery B; Infectious Diseases Service, Department of Medicine, Lausanne University Hospital and University of Lausanne, 1011 Lausanne, Switzerland.
Kox M; Radboud Center for Infectious Diseases, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.; Department of Intensive Care Medicine, Radboud University Medical Center, 6525 EP Nijmegen, The Netherlands.
Pickkers P; Radboud Center for Infectious Diseases, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.; Department of Intensive Care Medicine, Radboud University Medical Center, 6525 EP Nijmegen, The Netherlands.
Calandra T; Infectious Diseases Service, Department of Medicine, Lausanne University Hospital and University of Lausanne, 1011 Lausanne, Switzerland.; Service of Immunology and Allergy, Department of Medicine, Lausanne University Hospital and University of Lausanne, 1010 Lausanne, Switzerland.
Roger T; Infectious Diseases Service, Department of Medicine, Lausanne University Hospital and University of Lausanne, 1011 Lausanne, Switzerland.
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Źródło:
Cells [Cells] 2024 Feb 08; Vol. 13 (4). Date of Electronic Publication: 2024 Feb 08.
Typ publikacji:
Journal Article
MeSH Terms:
Endotoxemia*
Myeloid-Derived Suppressor Cells*
Humans ; Critical Illness ; Prognosis ; Critical Care ; Endotoxins
Czasopismo naukowe
Tytuł:
Targeting PMN-MDSCs via CD300ld receptor for cancer immunotherapy.
Autorzy:
Li Y; Institute of Pediatrics of Children's Hospital of Fudan University, Shanghai Key Laboratory of Medical Epigenetics, Institutes of Biomedical Sciences, Fudan University, Shanghai, China.; The Fifth People's Hospital of Shanghai, Institutes of Biomedical Sciences, Fudan University, Shanghai, China.
Wang C; State Key Laboratory of Cell Biology, Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.
Lu Z; The Fifth People's Hospital of Shanghai, Institutes of Biomedical Sciences, Fudan University, Shanghai, China.
Luo M; Institute of Pediatrics of Children's Hospital of Fudan University, Shanghai Key Laboratory of Medical Epigenetics, Institutes of Biomedical Sciences, Fudan University, Shanghai, China.
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Źródło:
Clinical and translational medicine [Clin Transl Med] 2024 Jan; Vol. 14 (1), pp. e1534.
Typ publikacji:
Journal Article
MeSH Terms:
Myeloid-Derived Suppressor Cells*
Neoplasms*/therapy
Humans ; Immunotherapy
Czasopismo naukowe
Tytuł:
The Functional Roles of MDSCs in Severe COVID-19 Pathogenesis.
Autorzy:
Len JS; School of Biological Sciences, Nanyang Technological University, Singapore 637551, Singapore.
Koh CWT; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore 169857, Singapore.
Chan KR; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore 169857, Singapore.
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Źródło:
Viruses [Viruses] 2023 Dec 23; Vol. 16 (1). Date of Electronic Publication: 2023 Dec 23.
Typ publikacji:
Journal Article; Review
MeSH Terms:
COVID-19*
Myeloid-Derived Suppressor Cells*
Aged ; Humans ; Post-Acute COVID-19 Syndrome ; Gene Expression Profiling ; Immunocompromised Host
Czasopismo naukowe
Tytuł:
Myeloid-derived suppressor cells inhibit natural killer cells in myelodysplastic syndromes through the TIGIT/CD155 pathway.
Autorzy:
Yue J; Department of Hematology, General Hospital of Tianjin Medical University, Tianjin, People's Republic of China.
Li J; Department of Hematology, General Hospital of Tianjin Medical University, Tianjin, People's Republic of China.
Ma J; Department of Hematology, General Hospital of Tianjin Medical University, Tianjin, People's Republic of China.
Zhai Y; Department of Hematology, General Hospital of Tianjin Medical University, Tianjin, People's Republic of China.
Shen L; Department of Hematology, General Hospital of Tianjin Medical University, Tianjin, People's Republic of China.
Zhang W; Department of Hematology, General Hospital of Tianjin Medical University, Tianjin, People's Republic of China.
Li L; Department of Hematology, General Hospital of Tianjin Medical University, Tianjin, People's Republic of China.
Fu R; Department of Hematology, General Hospital of Tianjin Medical University, Tianjin, People's Republic of China.
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Źródło:
Hematology (Amsterdam, Netherlands) [Hematology] 2023 Dec; Vol. 28 (1), pp. 2166333.
Typ publikacji:
Journal Article
MeSH Terms:
Myeloid-Derived Suppressor Cells*/metabolism
Myelodysplastic Syndromes*/metabolism
Humans ; Granzymes/metabolism ; Granzymes/pharmacology ; Perforin/metabolism ; Perforin/pharmacology ; NK Cell Lectin-Like Receptor Subfamily K/metabolism ; Killer Cells, Natural ; Cytokines ; Receptors, Immunologic/metabolism
Czasopismo naukowe
Tytuł:
Oncogenic PIK3CA recruits myeloid-derived suppressor cells to shape the immunosuppressive tumour microenvironment in luminal breast cancer through the 5-lipoxygenase-dependent arachidonic acid pathway.
Autorzy:
Li X; Cancer Molecular Diagnostics Core, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Tianjin's Clinical Research Center for Cancer, Tianjin, China.; Key Laboratory of Cancer Immunology and Biotherapy, Tianjin, China.; Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University, Ministry of Education, Tianjin, China.; Department of Thyroid and Neck, Affiliated Cancer Hospital of Zhengzhou University, Henan Cancer Hospital, Zhengzhou, China.
Chen G; Cancer Molecular Diagnostics Core, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Tianjin's Clinical Research Center for Cancer, Tianjin, China.; Key Laboratory of Cancer Immunology and Biotherapy, Tianjin, China.; Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University, Ministry of Education, Tianjin, China.
Wang F; Cancer Molecular Diagnostics Core, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Tianjin's Clinical Research Center for Cancer, Tianjin, China.; Key Laboratory of Cancer Immunology and Biotherapy, Tianjin, China.; Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University, Ministry of Education, Tianjin, China.
Guo X; Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University, Ministry of Education, Tianjin, China.; Department of Breast Pathology and Lab, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China.
Zhang R; Cancer Molecular Diagnostics Core, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Tianjin's Clinical Research Center for Cancer, Tianjin, China.; Key Laboratory of Cancer Immunology and Biotherapy, Tianjin, China.; Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University, Ministry of Education, Tianjin, China.
Liu P; Cancer Molecular Diagnostics Core, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Tianjin's Clinical Research Center for Cancer, Tianjin, China.; Key Laboratory of Cancer Immunology and Biotherapy, Tianjin, China.; Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University, Ministry of Education, Tianjin, China.
Dong L; Cancer Molecular Diagnostics Core, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Tianjin's Clinical Research Center for Cancer, Tianjin, China.; Key Laboratory of Cancer Immunology and Biotherapy, Tianjin, China.; Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University, Ministry of Education, Tianjin, China.
Yu W; Key Laboratory of Cancer Immunology and Biotherapy, Tianjin, China.; Department of Immunology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin's Clinical Research Center for Cancer, Tianjin, China.
Wang H; College of Life Sciences, Nankai University, Tianjin, China.
Wang H; Laboratory of Cancer Cell Biology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Caner, Tianjin's Clinical Research Center for Cancer, Tianjin, China.; Key Laboratory of Cancer Prevention and Therapy, Tianjin, China.
Yu J; Cancer Molecular Diagnostics Core, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Tianjin's Clinical Research Center for Cancer, Tianjin, China.; Key Laboratory of Cancer Immunology and Biotherapy, Tianjin, China.; Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University, Ministry of Education, Tianjin, China.
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Źródło:
Clinical and translational medicine [Clin Transl Med] 2023 Nov; Vol. 13 (11), pp. e1483.
Typ publikacji:
Journal Article
MeSH Terms:
Breast Neoplasms*/metabolism
Myeloid-Derived Suppressor Cells*
Female ; Humans ; Arachidonate 5-Lipoxygenase/genetics ; Arachidonate 5-Lipoxygenase/metabolism ; Arachidonic Acid/metabolism ; Class I Phosphatidylinositol 3-Kinases/genetics ; Class I Phosphatidylinositol 3-Kinases/metabolism ; Immunosuppressive Agents ; Leukotriene B4/metabolism ; Phosphatidylinositol 3-Kinases/genetics ; Phosphatidylinositol 3-Kinases/metabolism ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
Targeting the myeloid microenvironment in neuroblastoma.
Autorzy:
Stip MC; Center for Translational Immunology, University Medical Center Utrecht, 3584 CX, Utrecht, The Netherlands.
Teeuwen L; Center for Translational Immunology, University Medical Center Utrecht, 3584 CX, Utrecht, The Netherlands.
Dierselhuis MP; Princess Máxima Center for Pediatric Oncology, 3584 CS, Utrecht, The Netherlands.
Leusen JHW; Center for Translational Immunology, University Medical Center Utrecht, 3584 CX, Utrecht, The Netherlands.
Krijgsman D; Center for Translational Immunology, University Medical Center Utrecht, 3584 CX, Utrecht, The Netherlands. .; Center for Molecular Medicine, University Medical Center Utrecht, 3584 CX, Utrecht, the Netherlands. .
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Źródło:
Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2023 Dec 13; Vol. 42 (1), pp. 337. Date of Electronic Publication: 2023 Dec 13.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Neuroblastoma*/genetics
Neoplasms*/therapy
Myeloid-Derived Suppressor Cells*
Humans ; Myeloid Cells ; Immunotherapy ; Macrophages ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
A new histone deacetylase inhibitor remodels the tumor microenvironment by deletion of polymorphonuclear myeloid-derived suppressor cells and sensitizes prostate cancer to immunotherapy.
Autorzy:
Chen Z; Department of Urology and Guangdong Key Laboratory of Urology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.; Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA.
Yang X; Department of Plastic Surgery, The Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Chen Z; Department of Urology and Guangdong Key Laboratory of Urology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Li M; Department of Urology and Guangdong Key Laboratory of Urology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Wang W; The Second Ward of Urology, Qujing Affiliated Hospital of Kunming Medical University, Qujing, China.
Yang R; Department of Urology and Guangdong Key Laboratory of Urology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Wang Z; Department of Urology and Guangdong Key Laboratory of Urology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Ma Y; Department of Urology and Guangdong Key Laboratory of Urology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Xu Y; Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA.
Ao S; Department of Urology and Guangdong Key Laboratory of Urology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Liang L; Department of Urology and Guangdong Key Laboratory of Urology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Cai C; Department of Urology and Guangdong Key Laboratory of Urology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Wang C; Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA.
Deng T; Department of Urology and Guangdong Key Laboratory of Urology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Gu D; Department of Urology and Guangdong Key Laboratory of Urology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China. .
Zhou H; Department of Urology and Guangdong Key Laboratory of Urology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China. .; The Second Ward of Urology, Qujing Affiliated Hospital of Kunming Medical University, Qujing, China. .
Zeng G; Department of Urology and Guangdong Key Laboratory of Urology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China. .
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Źródło:
BMC medicine [BMC Med] 2023 Oct 25; Vol. 21 (1), pp. 402. Date of Electronic Publication: 2023 Oct 25.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Myeloid-Derived Suppressor Cells*/metabolism
Prostatic Neoplasms*/drug therapy
Prostatic Neoplasms*/genetics
Humans ; Male ; Animals ; Mice ; Histone Deacetylase Inhibitors/metabolism ; Histone Deacetylase Inhibitors/pharmacology ; Tumor Microenvironment ; Cell Line, Tumor ; Immunotherapy
Czasopismo naukowe
Tytuł:
E3 ligase TRIM28 promotes anti-PD-1 resistance in non-small cell lung cancer by enhancing the recruitment of myeloid-derived suppressor cells.
Autorzy:
Liang M; Department of Internal Medicine, Yijishan Hospital, The First Affiliated Hospital of Wannan Medical College, Wuhu, 241000, Anhui, China.
Sun Z; Department of Respiratory Medicine, Yijishan Hospital, The First Affiliated Hospital of Wannan Medical College, 2 Zheshan West Road, Wuhu, 241000, Anhui, China.
Chen X; Department of Respiratory Medicine, Yijishan Hospital, The First Affiliated Hospital of Wannan Medical College, 2 Zheshan West Road, Wuhu, 241000, Anhui, China.
Wang L; Department of Respiratory Medicine, Yijishan Hospital, The First Affiliated Hospital of Wannan Medical College, 2 Zheshan West Road, Wuhu, 241000, Anhui, China.
Wang H; Department of Respiratory Medicine, Yijishan Hospital, The First Affiliated Hospital of Wannan Medical College, 2 Zheshan West Road, Wuhu, 241000, Anhui, China.
Qin L; Department of Respiratory Medicine, Yijishan Hospital, The First Affiliated Hospital of Wannan Medical College, 2 Zheshan West Road, Wuhu, 241000, Anhui, China.
Zhao W; Department of Medical Oncology, Yijishan Hospital, The First Affiliated Hospital of Wannan Medical College, Wuhu, 241000, Anhui, China.
Geng B; Department of Respiratory Medicine, Yijishan Hospital, The First Affiliated Hospital of Wannan Medical College, 2 Zheshan West Road, Wuhu, 241000, Anhui, China. .
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Źródło:
Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2023 Oct 21; Vol. 42 (1), pp. 275. Date of Electronic Publication: 2023 Oct 21.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Non-Small-Cell Lung*/pathology
Lung Neoplasms*/metabolism
Myeloid-Derived Suppressor Cells*
Humans ; Mice ; Animals ; Ubiquitin-Protein Ligases/metabolism ; NF-kappa B/metabolism ; Disease Models, Animal ; Tumor Microenvironment ; Tripartite Motif-Containing Protein 28/genetics ; Tripartite Motif-Containing Protein 28/metabolism
Czasopismo naukowe
Tytuł:
Regnase-1 downregulation promotes pancreatic cancer through myeloid-derived suppressor cell-mediated evasion of anticancer immunity.
Autorzy:
Okabe J; Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Suita, Japan.
Kodama T; Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Suita, Japan.
Sato Y; Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Suita, Japan.
Shigeno S; Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Suita, Japan.
Matsumae T; Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Suita, Japan.
Daiku K; Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Suita, Japan.
Sato K; Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Suita, Japan.
Yoshioka T; Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Suita, Japan.
Shigekawa M; Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Suita, Japan.
Higashiguchi M; Department of Gastroenterological Surgery, Osaka University Graduate School of Medicine, Suita, Japan.
Kobayashi S; Department of Gastroenterological Surgery, Osaka University Graduate School of Medicine, Suita, Japan.
Hikita H; Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Suita, Japan.
Tatsumi T; Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Suita, Japan.
Okamoto T; Department of Microbiology, Juntendo University School of Medicine, Tokyo, Japan.; Institute for Advanced Co-Creation Studies, Research Institute for Microbial Diseases, Osaka University, Suita, Japan.
Satoh T; Department of Immunology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.
Eguchi H; Department of Gastroenterological Surgery, Osaka University Graduate School of Medicine, Suita, Japan.
Akira S; Laboratory of Host Defense, World Premier Institute Immunology Frontier Research Center, Osaka University, Suita, Japan.; Department of Host Defense, Research Institute for Microbial Diseases, Osaka University, Suita, Japan.
Takehara T; Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Suita, Japan. .
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Źródło:
Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2023 Oct 09; Vol. 42 (1), pp. 262. Date of Electronic Publication: 2023 Oct 09.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Pancreatic Ductal*/pathology
Myeloid-Derived Suppressor Cells*
Pancreatic Neoplasms*/pathology
Ribonucleases*/genetics
Animals ; Humans ; Mice ; Cell Line, Tumor ; Down-Regulation ; Inflammation/metabolism ; Mice, Knockout ; Pancreatic Neoplasms
Czasopismo naukowe
Tytuł:
Immunosuppressive Activity of Exosomes from Granulocytic Myeloid-Derived Suppressor Cells in a Murine Model of Immune Bone Marrow Failure.
Autorzy:
Manley AL; Hematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Chen J; Hematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Fitzgerald W; Intracellular Interactions, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.
Feng X; Hematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Young NS; Hematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Sep 28; Vol. 24 (19). Date of Electronic Publication: 2023 Sep 28.
Typ publikacji:
Journal Article
MeSH Terms:
Myeloid-Derived Suppressor Cells*
Exosomes*
MicroRNAs*/genetics
Pancytopenia*
Mice ; Animals ; CD8-Positive T-Lymphocytes ; Disease Models, Animal ; Granulocytes ; Immunosuppressive Agents/pharmacology ; Bone Marrow Failure Disorders
Czasopismo naukowe
Tytuł:
Identification and validation of Birc5 as a novel activated cell cycle program biomarker associated with infiltration of immunosuppressive myeloid-derived suppressor cells in hepatocellular carcinoma.
Autorzy:
Liu Y; Department of Radiation Oncology, Anhui Provincial Cancer Hospital, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
Chen X; Department of Gastrointestinal Oncology Surgery, Anhui Provincial Cancer Hospital, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
Luo W; Department of Pathology, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Zhao Y; Department of Radiation Oncology, Anhui Provincial Cancer Hospital, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
Nashan B; Organ Transplant Center, Department of Hepatobiliary and Transplantation Surgery, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
Huang L; Department of Oncology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Medical Center on Aging of Ruijin Hospital, MCARJH, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Yuan X; Organ Transplant Center, Department of Hepatobiliary and Transplantation Surgery, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
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Źródło:
Cancer medicine [Cancer Med] 2023 Aug; Vol. 12 (15), pp. 16370-16385. Date of Electronic Publication: 2023 Jun 16.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Carcinoma, Hepatocellular*/metabolism
Myeloid-Derived Suppressor Cells*
Liver Neoplasms*/metabolism
Animals ; Humans ; Leukocytes, Mononuclear/metabolism ; Cell Division ; Biomarkers/metabolism ; Tumor Microenvironment/genetics
Czasopismo naukowe
Tytuł:
Myeloid-Derived Suppressor Cells (MDSCs) in Ovarian Cancer-Looking Back and Forward.
Autorzy:
Okła K; The First Department of Oncologic Gynecology and Gynecology, Medical University of Lublin, 20-081 Lublin, Poland.; Department of Surgery, University of Michigan, Ann Arbor, MI 48109, USA.
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Źródło:
Cells [Cells] 2023 Jul 22; Vol. 12 (14). Date of Electronic Publication: 2023 Jul 22.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Myeloid-Derived Suppressor Cells*/pathology
Ovarian Neoplasms*/pathology
Female ; Humans ; Myeloid Cells ; Immunosuppression Therapy ; Immune Tolerance ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
Mesenchymal stem cells, as glioma exosomal immunosuppressive signal multipliers, enhance MDSCs immunosuppressive activity through the miR-21/SP1/DNMT1 positive feedback loop.
Autorzy:
Qiu W; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine and Institute of Brain and Brain-Inspired Science, Shandong University, 107 Wenhua Western Road, Jinan, Shandong, 250012, China.; Shandong Key Laboratory of Brain Function Remodeling, Jinan, Shandong, China.
Guo Q; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine and Institute of Brain and Brain-Inspired Science, Shandong University, 107 Wenhua Western Road, Jinan, Shandong, 250012, China.; Shandong Key Laboratory of Brain Function Remodeling, Jinan, Shandong, China.
Guo X; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine and Institute of Brain and Brain-Inspired Science, Shandong University, 107 Wenhua Western Road, Jinan, Shandong, 250012, China.; Shandong Key Laboratory of Brain Function Remodeling, Jinan, Shandong, China.; Department of Neurology, Loma Linda University Health, Loma Linda, CA, 92350, USA.
Wang C; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine and Institute of Brain and Brain-Inspired Science, Shandong University, 107 Wenhua Western Road, Jinan, Shandong, 250012, China.; Shandong Key Laboratory of Brain Function Remodeling, Jinan, Shandong, China.; Department of Neurosurgery, Qilu Hospital of Shandong University (Qingdao), Qingdao, Shandong, China.
Li B; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine and Institute of Brain and Brain-Inspired Science, Shandong University, 107 Wenhua Western Road, Jinan, Shandong, 250012, China.; Shandong Key Laboratory of Brain Function Remodeling, Jinan, Shandong, China.
Qi Y; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine and Institute of Brain and Brain-Inspired Science, Shandong University, 107 Wenhua Western Road, Jinan, Shandong, 250012, China.; Shandong Key Laboratory of Brain Function Remodeling, Jinan, Shandong, China.
Wang S; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine and Institute of Brain and Brain-Inspired Science, Shandong University, 107 Wenhua Western Road, Jinan, Shandong, 250012, China.; Shandong Key Laboratory of Brain Function Remodeling, Jinan, Shandong, China.
Zhao R; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine and Institute of Brain and Brain-Inspired Science, Shandong University, 107 Wenhua Western Road, Jinan, Shandong, 250012, China.; Shandong Key Laboratory of Brain Function Remodeling, Jinan, Shandong, China.
Han X; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine and Institute of Brain and Brain-Inspired Science, Shandong University, 107 Wenhua Western Road, Jinan, Shandong, 250012, China.; Shandong Key Laboratory of Brain Function Remodeling, Jinan, Shandong, China.; Department of Neurosurgery, Jinan Children's Hospital, Jinan, Shandong, China.
Du H; Department of Cell Biology, University of Connecticut School of Medicine, Farmington, CT, 06030, USA.
Zhao S; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine and Institute of Brain and Brain-Inspired Science, Shandong University, 107 Wenhua Western Road, Jinan, Shandong, 250012, China.; Shandong Key Laboratory of Brain Function Remodeling, Jinan, Shandong, China.
Pan Z; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine and Institute of Brain and Brain-Inspired Science, Shandong University, 107 Wenhua Western Road, Jinan, Shandong, 250012, China.; Shandong Key Laboratory of Brain Function Remodeling, Jinan, Shandong, China.
Fan Y; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine and Institute of Brain and Brain-Inspired Science, Shandong University, 107 Wenhua Western Road, Jinan, Shandong, 250012, China.; Shandong Key Laboratory of Brain Function Remodeling, Jinan, Shandong, China.
Wang Q; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine and Institute of Brain and Brain-Inspired Science, Shandong University, 107 Wenhua Western Road, Jinan, Shandong, 250012, China.; Shandong Key Laboratory of Brain Function Remodeling, Jinan, Shandong, China.
Gao Z; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine and Institute of Brain and Brain-Inspired Science, Shandong University, 107 Wenhua Western Road, Jinan, Shandong, 250012, China.; Shandong Key Laboratory of Brain Function Remodeling, Jinan, Shandong, China.
Li G; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine and Institute of Brain and Brain-Inspired Science, Shandong University, 107 Wenhua Western Road, Jinan, Shandong, 250012, China. .; Shandong Key Laboratory of Brain Function Remodeling, Jinan, Shandong, China. .
Xue H; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine and Institute of Brain and Brain-Inspired Science, Shandong University, 107 Wenhua Western Road, Jinan, Shandong, 250012, China. .; Shandong Key Laboratory of Brain Function Remodeling, Jinan, Shandong, China. .
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Źródło:
Journal of nanobiotechnology [J Nanobiotechnology] 2023 Jul 22; Vol. 21 (1), pp. 233. Date of Electronic Publication: 2023 Jul 22.
Typ publikacji:
Journal Article
MeSH Terms:
Glioma*
MicroRNAs*/genetics
Myeloid-Derived Suppressor Cells*
Humans ; Feedback ; Immunosuppressive Agents ; Tumor Microenvironment ; Mesenchymal Stem Cells/immunology ; Mesenchymal Stem Cells/metabolism ; Exosomes/genetics ; Exosomes/metabolism ; Sp1 Transcription Factor
Czasopismo naukowe
Tytuł:
Abnormal activation of NF-κB and MAPK signaling pathways affect osimertinib resistance and influence the recruitment of myeloid-derived suppressor cells to shape the immunosuppressive tumor immune microenvironment.
Autorzy:
Wang C; State Key Laboratory of Molecular Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.; Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Fei K; State Key Laboratory of Molecular Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.; Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Liu L; State Key Laboratory of Molecular Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.; Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Duan J; State Key Laboratory of Molecular Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.; Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Wang Z; State Key Laboratory of Molecular Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.; Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Li S; State Key Laboratory of Molecular Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Xu J; State Key Laboratory of Molecular Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.; Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.; Guangdong Provincial People's Hospital/Guangdong Provincial Academy of Medical Sciences, Guangdong Provincial Key Laboratory of Translational Medicine in Lung Cancer, Guangdong, China.
Zhang X; State Key Laboratory of Molecular Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Tian Y; State Key Laboratory of Molecular Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Qu Y; State Key Laboratory of Molecular Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Bai H; State Key Laboratory of Molecular Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.; Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Wang J; State Key Laboratory of Molecular Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.; Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
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Źródło:
Thoracic cancer [Thorac Cancer] 2023 Jul; Vol. 14 (19), pp. 1843-1856. Date of Electronic Publication: 2023 May 23.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Lung Neoplasms*/pathology
Carcinoma, Non-Small-Cell Lung*/pathology
Myeloid-Derived Suppressor Cells*/metabolism
Myeloid-Derived Suppressor Cells*/pathology
Humans ; ErbB Receptors/genetics ; NF-kappa B/genetics ; Drug Resistance, Neoplasm/genetics ; Mutation ; Protein Kinase Inhibitors/therapeutic use ; Signal Transduction ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
The distribution of myeloid-derived suppressor cells subsets and up-regulation of programmed death-1/PD-L1 axis in peripheral blood of adult CAP patients.
Autorzy:
Gong H; Department of Respiratory and Critical Care Medicine, Affiliated Hospital of Qingdao University Medical College, Qingdao, China.
Zhao J; Department of Respiratory and Critical Care Medicine, Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China.
Xu W; Department of Respiratory and Critical Care Medicine, Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China.
Wan Y; Department of Respiratory and Critical Care Medicine, Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China.
Mu X; Department of Respiratory and Critical Care Medicine, Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China.
Zhang M; Department of Respiratory and Critical Care Medicine, Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China.
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Źródło:
PloS one [PLoS One] 2023 Sep 27; Vol. 18 (9), pp. e0291455. Date of Electronic Publication: 2023 Sep 27 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Myeloid-Derived Suppressor Cells*
Pneumonia*
Community-Acquired Infections*
Humans ; Adult ; Up-Regulation ; B7-H1 Antigen ; Cross-Sectional Studies ; Leukocytes, Mononuclear ; Programmed Cell Death 1 Receptor
Czasopismo naukowe
Tytuł:
The immunosuppressive activity of myeloid-derived suppressor cells in murine Paracoccidioidomycosis relies on Indoleamine 2,3-dioxygenase activity and Dectin-1 and TLRs signaling.
Autorzy:
Kaminski VL; Institute of Science and Technology, Federal University of São Paulo - UNIFESP, São José dos Campos, SP, Brazil.
Preite NW; Institute of Science and Technology, Federal University of São Paulo - UNIFESP, São José dos Campos, SP, Brazil.
Borges BM; Institute of Science and Technology, Federal University of São Paulo - UNIFESP, São José dos Campos, SP, Brazil.
Dos Santos BV; Institute of Science and Technology, Federal University of São Paulo - UNIFESP, São José dos Campos, SP, Brazil.
Calich VLG; Department of Immunology, Institute of Biomedical Sciences, University of São Paulo - USP, São Paulo, Brazil.
Loures FV; Institute of Science and Technology, Federal University of São Paulo - UNIFESP, São José dos Campos, SP, Brazil. .
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Źródło:
Scientific reports [Sci Rep] 2023 Jul 31; Vol. 13 (1), pp. 12391. Date of Electronic Publication: 2023 Jul 31.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Myeloid-Derived Suppressor Cells*
Paracoccidioidomycosis*
Animals ; Mice ; Indoleamine-Pyrrole 2,3,-Dioxygenase/metabolism ; Toll-Like Receptor 2/metabolism ; Toll-Like Receptor 4/metabolism ; Mice, Knockout
Czasopismo naukowe
Tytuł:
LILRB4 regulates the function of decidual MDSCs via the SHP-2/STAT6 pathway during Toxoplasma gondii infection.
Autorzy:
Li Y; Department of Gynecology and Obstetrics, Yantai Affiliated Hospital of Binzhou Medical University, Yantai, Shandong, People's Republic of China.
Guo J; Department of Gynecology and Obstetrics, Yantai Affiliated Hospital of Binzhou Medical University, Yantai, Shandong, People's Republic of China.
Zhang H; Department of Immunology, Binzhou Medical University, Yantai, 264003, Shandong, People's Republic of China.
Li Z; Department of Immunology, Binzhou Medical University, Yantai, 264003, Shandong, People's Republic of China.
Ren Y; Department of Immunology, Binzhou Medical University, Yantai, 264003, Shandong, People's Republic of China.
Jiang Y; Department of Immunology, Binzhou Medical University, Yantai, 264003, Shandong, People's Republic of China.
Liu X; Department of Immunology, Binzhou Medical University, Yantai, 264003, Shandong, People's Republic of China.
Hu X; Department of Immunology, Binzhou Medical University, Yantai, 264003, Shandong, People's Republic of China. .
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Źródło:
Parasites & vectors [Parasit Vectors] 2023 Jul 17; Vol. 16 (1), pp. 237. Date of Electronic Publication: 2023 Jul 17.
Typ publikacji:
Journal Article
MeSH Terms:
Myeloid-Derived Suppressor Cells*
Toxoplasma*/genetics
Toxoplasmosis*/genetics
Animals ; Female ; Humans ; Mice ; Pregnancy ; Interleukin-10/genetics ; Interleukin-10/metabolism ; STAT6 Transcription Factor/genetics ; STAT6 Transcription Factor/metabolism ; Protein Tyrosine Phosphatase, Non-Receptor Type 11
Czasopismo naukowe
Tytuł:
Th17/Treg balance is regulated by myeloid-derived suppressor cells in experimental autoimmune myocarditis.
Autorzy:
Xiong X; Department of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Yu M; Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Wang D; Department of Emergency, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Wang Y; Department of Cardiology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Cheng L; Laboratory of Cardiovascular Immunology, Institute of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
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Źródło:
Immunity, inflammation and disease [Immun Inflamm Dis] 2023 Jun; Vol. 11 (6), pp. e872.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Myocarditis*
Myeloid-Derived Suppressor Cells*
Humans ; Interleukin-17 ; T-Lymphocytes, Regulatory ; Th17 Cells ; Inflammation
Czasopismo naukowe
Tytuł:
Cytokine-Induced Myeloid-Derived Suppressor Cells Demonstrate Their Immunoregulatory Functions to Prolong the Survival of Diabetic Mice.
Autorzy:
Li TT; Division of General Surgery, Chang-Gung Memorial Hospital, Chiayi 61302, Taiwan.
Lin CL; Department of Nephrology, Chang-Gung Memorial Hospital, Chiayi 61302, Taiwan.; Kidney and Diabetic Complications Research Team (KDCRT), Chang-Gung Memorial Hospital, Chiayi 61302, Taiwan.; College of Medicine, Chang-Gung University, Taoyuan 33302, Taiwan.
Chiang M; Division of General Surgery, Chang-Gung Memorial Hospital, Chiayi 61302, Taiwan.
He JT; Division of General Surgery, Chang-Gung Memorial Hospital, Chiayi 61302, Taiwan.
Hung CH; College of Medicine, Chang-Gung University, Taoyuan 33302, Taiwan.; Division of Infectious Diseases, Chang-Gung Memorial Hospital, Chiayi 61302, Taiwan.
Hsieh CC; Division of General Surgery, Chang-Gung Memorial Hospital, Chiayi 61302, Taiwan.; Kidney and Diabetic Complications Research Team (KDCRT), Chang-Gung Memorial Hospital, Chiayi 61302, Taiwan.; College of Medicine, Chang-Gung University, Taoyuan 33302, Taiwan.
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Źródło:
Cells [Cells] 2023 May 29; Vol. 12 (11). Date of Electronic Publication: 2023 May 29.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Myeloid-Derived Suppressor Cells*
Diabetes Mellitus, Experimental*/therapy
Mice ; Animals ; Cytokines/pharmacology ; Granulocyte-Macrophage Colony-Stimulating Factor/pharmacology ; Mice, Inbred NOD
Czasopismo naukowe
Tytuł:
Chronic psychological stress promotes breast cancer pre-metastatic niche formation by mobilizing splenic MDSCs via TAM/CXCL1 signaling.
Autorzy:
Zheng Y; State Key Laboratory of Dampness Syndrome of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510006, China.; Integrative Research Laboratory of Breast Cancer, Discipline of Integrated Chinese and Western Medicine, The Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, 510006, China.; Guangdong-Hong Kong-Macau Joint Lab on Chinese Medicine and Immune Disease Research, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, 510006, China.
Wang N; Integrative Research Laboratory of Breast Cancer, Discipline of Integrated Chinese and Western Medicine, The Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, 510006, China.; Guangdong-Hong Kong-Macau Joint Lab on Chinese Medicine and Immune Disease Research, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, 510006, China.; Guangdong Provincial Key Laboratory of Clinical Research on Traditional Chinese Medicine Syndrome, Guangdong Provincial Academy of Chinese Medical Sciences, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, Guangdong, 510006, China.; The Research Center for Integrative Medicine, School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, 510006, China.
Wang S; State Key Laboratory of Dampness Syndrome of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510006, China.; Integrative Research Laboratory of Breast Cancer, Discipline of Integrated Chinese and Western Medicine, The Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, 510006, China.; Guangdong-Hong Kong-Macau Joint Lab on Chinese Medicine and Immune Disease Research, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, 510006, China.; Guangdong Provincial Key Laboratory of Clinical Research on Traditional Chinese Medicine Syndrome, Guangdong Provincial Academy of Chinese Medical Sciences, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, Guangdong, 510006, China.
Zhang J; State Key Laboratory of Dampness Syndrome of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510006, China.; Integrative Research Laboratory of Breast Cancer, Discipline of Integrated Chinese and Western Medicine, The Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, 510006, China.; Guangdong-Hong Kong-Macau Joint Lab on Chinese Medicine and Immune Disease Research, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, 510006, China.
Yang B; State Key Laboratory of Dampness Syndrome of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510006, China.; Integrative Research Laboratory of Breast Cancer, Discipline of Integrated Chinese and Western Medicine, The Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, 510006, China.
Wang Z; State Key Laboratory of Dampness Syndrome of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510006, China. .; Integrative Research Laboratory of Breast Cancer, Discipline of Integrated Chinese and Western Medicine, The Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, 510006, China. .; Guangdong-Hong Kong-Macau Joint Lab on Chinese Medicine and Immune Disease Research, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, 510006, China. .; Guangdong Provincial Key Laboratory of Clinical Research on Traditional Chinese Medicine Syndrome, Guangdong Provincial Academy of Chinese Medical Sciences, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, Guangdong, 510006, China. .; The Research Center for Integrative Medicine, School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, 510006, China. .
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Źródło:
Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2023 May 20; Vol. 42 (1), pp. 129. Date of Electronic Publication: 2023 May 20.
Typ publikacji:
Journal Article
MeSH Terms:
Breast Neoplasms*/pathology
Melanoma*/pathology
Myeloid-Derived Suppressor Cells*
Stress, Psychological*/complications
Female ; Humans ; Chemokine CXCL1/metabolism ; Spleen/metabolism ; Spleen/pathology ; Tumor Microenvironment ; Melanoma, Cutaneous Malignant
Czasopismo naukowe
Tytuł:
Galectin-9 and myeloid-derived suppressor cell as prognostic indicators for chronic lymphocytic leukemia.
Autorzy:
Alimu X; Center of Hematology, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China.
Zhang J; Senior Department of Hematology, The Fifth Medical Center of PLA General Hospital, Beijing, China.
Pang N; CAS Key Lab of Bio-Medical Diagnostics, Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou, China.; Hematology Institute of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, China.
Zhang R; Center of Hematology, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China.; Hematology Institute of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, China.
Chen R; Center of Hematology, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China.; Hematology Institute of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, China.
Zeng X; Center of Hematology, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China.
Tudahong S; Center of Hematology, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China.
Chen G; Center of Hematology, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China.; Hematology Institute of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, China.
Muhashi M; Center of Hematology, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China.; Hematology Institute of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, China.
Zhao F; Center of Hematology, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China.; Hematology Institute of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, China.
Ding J; Department of Immunology, School of Basic Medical Sciences, Xinjiang Medical University, Urumqi, Xinjiang, China.
Qu J; Center of Hematology, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China.; Hematology Institute of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, China.
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Źródło:
Immunity, inflammation and disease [Immun Inflamm Dis] 2023 May; Vol. 11 (5), pp. e853.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Leukemia, Lymphocytic, Chronic, B-Cell*/diagnosis
Myeloid-Derived Suppressor Cells*/metabolism
Myeloid-Derived Suppressor Cells*/pathology
Humans ; Prognosis ; Hepatitis A Virus Cellular Receptor 2/metabolism ; CD8-Positive T-Lymphocytes ; Leukocytes, Mononuclear ; Galectins/metabolism
Czasopismo naukowe
Tytuł:
Tim-3 regulates the immunosuppressive function of decidual MDSCs via the Fyn-STAT3-C/EBPβ pathway during Toxoplasma gondii infection.
Autorzy:
Qi H; Department of Immunology, Binzhou Medical University, Yantai, Shandong, P. R. China.
Li Y; Department of Gynecology and Obstetrics, Yantai Affiliated Hospital of Binzhou Medical University, Yantai, Shandong, P. R. China.
Liu X; Department of Immunology, Binzhou Medical University, Yantai, Shandong, P. R. China.
Jiang Y; Department of Immunology, Binzhou Medical University, Yantai, Shandong, P. R. China.
Li Z; Department of Immunology, Binzhou Medical University, Yantai, Shandong, P. R. China.
Xu X; Department of Immunology, Binzhou Medical University, Yantai, Shandong, P. R. China.
Zhang H; Department of Immunology, Binzhou Medical University, Yantai, Shandong, P. R. China.
Hu X; Department of Immunology, Binzhou Medical University, Yantai, Shandong, P. R. China.
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Źródło:
PLoS pathogens [PLoS Pathog] 2023 Apr 14; Vol. 19 (4), pp. e1011329. Date of Electronic Publication: 2023 Apr 14 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Myeloid-Derived Suppressor Cells*/metabolism
Toxoplasma*/metabolism
Toxoplasmosis*/metabolism
Animals ; Female ; Humans ; Mice ; Pregnancy ; Hepatitis A Virus Cellular Receptor 2/genetics ; Hepatitis A Virus Cellular Receptor 2/metabolism ; Interleukin-10/genetics ; Interleukin-10/metabolism ; Pregnancy Outcome ; STAT3 Transcription Factor/genetics ; STAT3 Transcription Factor/metabolism
Czasopismo naukowe
Tytuł:
FAP-targeted CAR-T suppresses MDSCs recruitment to improve the antitumor efficacy of claudin18.2-targeted CAR-T against pancreatic cancer.
Autorzy:
Liu Y; State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, No. 25/Ln2200 XieTu Road, Shanghai, 200032, China.
Sun Y; State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, No. 25/Ln2200 XieTu Road, Shanghai, 200032, China.
Wang P; CARsgen Therapeutics, Shanghai, 200032, China.
Li S; State Key Laboratory for Oncogenes and Related Genes, Renji-Med X Clinical Stem Cell Research Center, Ren Ji Hospital, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200030, China.
Dong Y; State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, No. 25/Ln2200 XieTu Road, Shanghai, 200032, China.
Zhou M; State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, No. 25/Ln2200 XieTu Road, Shanghai, 200032, China.
Shi B; CARsgen Therapeutics, Shanghai, 200032, China.
Jiang H; State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, No. 25/Ln2200 XieTu Road, Shanghai, 200032, China.; CARsgen Therapeutics, Shanghai, 200032, China.
Sun R; State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, No. 25/Ln2200 XieTu Road, Shanghai, 200032, China. .
Li Z; State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, No. 25/Ln2200 XieTu Road, Shanghai, 200032, China. .; CARsgen Therapeutics, Shanghai, 200032, China. .
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Źródło:
Journal of translational medicine [J Transl Med] 2023 Apr 12; Vol. 21 (1), pp. 255. Date of Electronic Publication: 2023 Apr 12.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Carcinoma, Pancreatic Ductal*/therapy
Myeloid-Derived Suppressor Cells*/metabolism
Pancreatic Neoplasms*/therapy
Pancreatic Neoplasms*/metabolism
Receptors, Chimeric Antigen*/metabolism
Animals ; Mice ; CD8-Positive T-Lymphocytes ; Cell Line, Tumor ; Serine Endopeptidases/metabolism ; Tumor Microenvironment ; Humans ; Pancreatic Neoplasms
Czasopismo naukowe
Tytuł:
Targeting myeloid-derived suppressor cells in combination with tumor cell vaccination predicts anti-tumor immunity and breast cancer dormancy: an in silico experiment.
Autorzy:
Mehdizadeh R; Institute of Biochemistry and Biophysics, University of Tehran, Tehran, Iran. .
Shariatpanahi SP; Institute of Biochemistry and Biophysics, University of Tehran, Tehran, Iran.
Goliaei B; Institute of Biochemistry and Biophysics, University of Tehran, Tehran, Iran.
Rüegg C; Laboratory of Experimental and Translational Oncology, Pathology, Department of Oncology, Microbiology and Immunology, Faculty of Sciences and Medicine, University of Fribourg, Fribourg, Switzerland. .
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Źródło:
Scientific reports [Sci Rep] 2023 Apr 11; Vol. 13 (1), pp. 5875. Date of Electronic Publication: 2023 Apr 11.
Typ publikacji:
Journal Article
MeSH Terms:
Myeloid-Derived Suppressor Cells*
Triple Negative Breast Neoplasms*/metabolism
Humans ; Animals ; Mice ; Cell Line, Tumor ; Immunotherapy ; Vaccination ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
Combining Cryo-Thermal Therapy with Anti-IL-6 Treatment Promoted the Maturation of MDSCs to Induce Long-Term Survival in a Mouse Model of Breast Cancer.
Autorzy:
Du P; School of Biomedical Engineering and Med-X Research Institute, Shanghai Jiao Tong University, Shanghai 200030, China.
Zheng J; School of Biomedical Engineering and Med-X Research Institute, Shanghai Jiao Tong University, Shanghai 200030, China.
Wang S; School of Biomedical Engineering and Med-X Research Institute, Shanghai Jiao Tong University, Shanghai 200030, China.
Lou Y; School of Biomedical Engineering and Med-X Research Institute, Shanghai Jiao Tong University, Shanghai 200030, China.
Zhang Z; School of Biomedical Engineering and Med-X Research Institute, Shanghai Jiao Tong University, Shanghai 200030, China.
Wang J; School of Biomedical Engineering and Med-X Research Institute, Shanghai Jiao Tong University, Shanghai 200030, China.
Zhu Y; School of Biomedical Engineering and Med-X Research Institute, Shanghai Jiao Tong University, Shanghai 200030, China.
You J; School of Biomedical Engineering and Med-X Research Institute, Shanghai Jiao Tong University, Shanghai 200030, China.
Zhang A; School of Biomedical Engineering and Med-X Research Institute, Shanghai Jiao Tong University, Shanghai 200030, China.
Liu P; School of Biomedical Engineering and Med-X Research Institute, Shanghai Jiao Tong University, Shanghai 200030, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Apr 10; Vol. 24 (8). Date of Electronic Publication: 2023 Apr 10.
Typ publikacji:
Journal Article
MeSH Terms:
Myeloid-Derived Suppressor Cells*
Animals ; Mice ; Neoplasm Recurrence, Local ; Disease Models, Animal ; Th1 Cells ; Combined Modality Therapy
Czasopismo naukowe
Tytuł:
Involvement of CX3CR1 cells appearing in the abdominal cavity in the immunosuppressive environment immediately after gastric cancer surgery.
Autorzy:
Natsuki, Seiji (AUTHOR)
Yoshii, Mami (AUTHOR)
Tanaka, Hiroaki (AUTHOR)
Mori, Takuya (AUTHOR)
Deguchi, Sota (AUTHOR)
Miki, Yuichiro (AUTHOR)
Tamura, Tatsuro (AUTHOR)
Toyokawa, Takahiro (AUTHOR)
Lee, Shigeru (AUTHOR)
Maeda, Kiyoshi (AUTHOR)
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Źródło:
World Journal of Surgical Oncology. 3/7/2024, Vol. 22 Issue 1, p1-13. 13p.
Czasopismo naukowe
Tytuł:
Multiple treatments with human embryonic stem cell-derived mesenchymal progenitor cells preserved the fertility and ovarian function of perimenopausal mice undergoing natural aging.
Autorzy:
Shin, Eun-Young (AUTHOR)
Jeong, Suji (AUTHOR)
Lee, Jeoung Eun (AUTHOR)
Jeong, Dong Seok (AUTHOR)
Han, Dong Keun (AUTHOR)
Hong, Seok-Ho (AUTHOR)
Lee, Dong Ryul (AUTHOR)
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Źródło:
Stem Cell Research & Therapy. 3/3/2024, Vol. 15 Issue 1, p1-13. 13p.
Czasopismo naukowe
Tytuł:
Intracerebellar injection of monocytic immature myeloid cells prevents the adverse effects caused by stereotactic surgery in a model of cerebellar neurodegeneration.
Autorzy:
del Pilar, Carlos (AUTHOR)
Garrido-Matilla, Lucía (AUTHOR)
del Pozo-Filíu, Lucía (AUTHOR)
Lebrón-Galán, Rafael (AUTHOR)
Arias, Raúl F. (AUTHOR)
Clemente, Diego (AUTHOR)
Alonso, José Ramón (AUTHOR)
Weruaga, Eduardo (AUTHOR)
Díaz, David (AUTHOR)
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Źródło:
Journal of Neuroinflammation. 2/14/2024, Vol. 21 Issue 1, p1-22. 22p.
Czasopismo naukowe
Tytuł:
Single-cell profiling of the microenvironment in human bone metastatic renal cell carcinoma.
Autorzy:
Ma, Fen (AUTHOR)
Wang, Shuoer (AUTHOR)
Xu, Lun (AUTHOR)
Huang, Wending (AUTHOR)
Shi, Guohai (AUTHOR)
Sun, Zhengwang (AUTHOR)
Cai, Weiluo (AUTHOR)
Wu, Zhiqiang (AUTHOR)
Huang, Yiming (AUTHOR)
Meng, Juan (AUTHOR)
Sun, Yining (AUTHOR)
Fang, Meng (AUTHOR)
Cheng, Mo (AUTHOR)
Ji, Yingzheng (AUTHOR)
Hu, Tu (AUTHOR)
Zhang, Yunkui (AUTHOR)
Gu, Bingxin (AUTHOR)
Zhang, Jiwei (AUTHOR)
Song, Shaoli (AUTHOR)
Sun, Yidi (AUTHOR)
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Źródło:
Communications Biology. 1/12/2024, Vol. 7 Issue 1, p1-16. 16p.
Czasopismo naukowe
Tytuł:
Defining the Emergence of New Immunotherapy Approaches in Breast Cancer: Role of Myeloid-Derived Suppressor Cells.
Autorzy:
Sánchez-León ML; Laboratory Service, Department of Medical Biochemistry, Molecular Biology and Immunology, School of Medicine, Virgen Macarena University Hospital, University of Seville, 41009 Seville, Spain.; Oncology Service, Virgen Macarena University Hospital, Department of Medicine, School of Medicine, University of Seville, 41009 Seville, Spain.
Jiménez-Cortegana C; Laboratory Service, Department of Medical Biochemistry, Molecular Biology and Immunology, School of Medicine, Virgen Macarena University Hospital, University of Seville, 41009 Seville, Spain.; Oncology Service, Virgen Macarena University Hospital, Department of Medicine, School of Medicine, University of Seville, 41009 Seville, Spain.
Silva Romeiro S; Oncology Service, Virgen Macarena University Hospital, Department of Medicine, School of Medicine, University of Seville, 41009 Seville, Spain.
Garnacho C; Department of Normal and Pathological Cytology and Histology, School of Medicine, University of Seville, 41009 Seville, Spain.
de la Cruz-Merino L; Oncology Service, Virgen Macarena University Hospital, Department of Medicine, School of Medicine, University of Seville, 41009 Seville, Spain.
García-Domínguez DJ; Laboratory Service, Department of Medical Biochemistry, Molecular Biology and Immunology, School of Medicine, Virgen Macarena University Hospital, University of Seville, 41009 Seville, Spain.; Oncology Service, Virgen Macarena University Hospital, Department of Medicine, School of Medicine, University of Seville, 41009 Seville, Spain.
Hontecillas-Prieto L; Laboratory Service, Department of Medical Biochemistry, Molecular Biology and Immunology, School of Medicine, Virgen Macarena University Hospital, University of Seville, 41009 Seville, Spain.; Oncology Service, Virgen Macarena University Hospital, Department of Medicine, School of Medicine, University of Seville, 41009 Seville, Spain.
Sánchez-Margalet V; Laboratory Service, Department of Medical Biochemistry, Molecular Biology and Immunology, School of Medicine, Virgen Macarena University Hospital, University of Seville, 41009 Seville, Spain.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Mar 08; Vol. 24 (6). Date of Electronic Publication: 2023 Mar 08.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Breast Neoplasms*/drug therapy
Myeloid-Derived Suppressor Cells*
Neoplasms*/therapy
Humans ; Female ; Immunotherapy ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
Targeting tumour-reprogrammed myeloid cells: the new battleground in cancer immunotherapy.
Autorzy:
De Sanctis F; Immunology Section, University Hospital and Department of Medicine, University of Verona, 37134, Verona, Italy.
Adamo A; Immunology Section, University Hospital and Department of Medicine, University of Verona, 37134, Verona, Italy.
Canè S; Immunology Section, University Hospital and Department of Medicine, University of Verona, 37134, Verona, Italy.
Ugel S; Immunology Section, University Hospital and Department of Medicine, University of Verona, 37134, Verona, Italy. .
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Źródło:
Seminars in immunopathology [Semin Immunopathol] 2023 Mar; Vol. 45 (2), pp. 163-186. Date of Electronic Publication: 2022 Sep 26.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Neoplasms*
Myeloid-Derived Suppressor Cells*
Humans ; Ecosystem ; Myeloid Cells ; Immunotherapy ; Macrophages ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
Lower frequency of MDSCs was significantly related to functional cure in CHB patients treated with peginterferon.
Autorzy:
Zhang Y; Department of Infectious Diseases, Shanghai Key Laboratory of Infectious Diseases and Biosafety Emergency Response, National Medical Center for Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, China.
Han J; Department of Infectious Diseases, Shanghai Key Laboratory of Infectious Diseases and Biosafety Emergency Response, National Medical Center for Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, China.
Zhang X; Department of Infectious Diseases, Shanghai Key Laboratory of Infectious Diseases and Biosafety Emergency Response, National Medical Center for Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, China.
Li F; Department of Infectious Diseases, Shanghai Key Laboratory of Infectious Diseases and Biosafety Emergency Response, National Medical Center for Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, China.
Guo Y; Department of Infectious Diseases, Shanghai Key Laboratory of Infectious Diseases and Biosafety Emergency Response, National Medical Center for Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, China.
He J; Department of Infectious Diseases, Shanghai Key Laboratory of Infectious Diseases and Biosafety Emergency Response, National Medical Center for Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, China.
Mao R; Department of Infectious Diseases, Shanghai Key Laboratory of Infectious Diseases and Biosafety Emergency Response, National Medical Center for Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, China.
Zhu H; Department of Infectious Diseases, Shanghai Key Laboratory of Infectious Diseases and Biosafety Emergency Response, National Medical Center for Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, China.
Yu J; Department of Infectious Diseases, Shanghai Key Laboratory of Infectious Diseases and Biosafety Emergency Response, National Medical Center for Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, China.
Huang Y; Department of Infectious Diseases, Shanghai Key Laboratory of Infectious Diseases and Biosafety Emergency Response, National Medical Center for Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, China.
Yang F; Department of Infectious Diseases, Shanghai Key Laboratory of Infectious Diseases and Biosafety Emergency Response, National Medical Center for Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, China.
Zhang J; Department of Infectious Diseases, Shanghai Key Laboratory of Infectious Diseases and Biosafety Emergency Response, National Medical Center for Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, China.; Shanghai Institute of Infectious Diseases and Biosecurity, Key Laboratory of Medical Molecular Virology (MOE/MOH), Shanghai Medical College, Fudan University, Shanghai, China.; Department of Infectious Diseases, Jing'An Branch of Huashan Hospital, Fudan University, Shanghai, China.
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Źródło:
Liver international : official journal of the International Association for the Study of the Liver [Liver Int] 2023 Feb; Vol. 43 (2), pp. 329-339. Date of Electronic Publication: 2022 Dec 07.
Typ publikacji:
Journal Article
MeSH Terms:
Hepatitis B, Chronic*
Myeloid-Derived Suppressor Cells*
Humans ; Hepatitis B Surface Antigens ; Antiviral Agents ; Hepatitis B e Antigens ; Polyethylene Glycols/therapeutic use ; Recombinant Proteins/therapeutic use ; Hepatitis B virus/genetics ; DNA, Viral
Czasopismo naukowe
Tytuł:
TIM3/CEACAM1 pathway involves in myeloid-derived suppressor cells induced CD8 T cells exhaustion and bone marrow inflammatory microenvironment in myelodysplastic syndrome.
Autorzy:
Yu S; Department of Hematology, Tianjin Medical University General Hospital, Tianjin 300052, China. Address:Heping District 154 Anshan Road, Tianjin, China.
Ren X; Department of Hematology, Tianjin Medical University General Hospital, Tianjin 300052, China. Address:Heping District 154 Anshan Road, Tianjin, China.
Meng F; Department of Hematology, Tianjin Medical University General Hospital, Tianjin 300052, China. Address:Heping District 154 Anshan Road, Tianjin, China.
Guo X; Department of Hematology, Tianjin Medical University General Hospital, Tianjin 300052, China. Address:Heping District 154 Anshan Road, Tianjin, China.
Tao J; Department of Hematology, Tianjin Medical University General Hospital, Tianjin 300052, China. Address:Heping District 154 Anshan Road, Tianjin, China.
Zhang W; Department of Hematology, Tianjin Medical University General Hospital, Tianjin 300052, China. Address:Heping District 154 Anshan Road, Tianjin, China.
Liu Z; Department of Hematology, Tianjin Medical University General Hospital, Tianjin 300052, China. Address:Heping District 154 Anshan Road, Tianjin, China.
Fu R; Department of Hematology, Tianjin Medical University General Hospital, Tianjin 300052, China. Address:Heping District 154 Anshan Road, Tianjin, China.
Li L; Department of Hematology, Tianjin Medical University General Hospital, Tianjin 300052, China. Address:Heping District 154 Anshan Road, Tianjin, China.
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Źródło:
Immunology [Immunology] 2023 Feb; Vol. 168 (2), pp. 273-289. Date of Electronic Publication: 2022 May 03.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Myelodysplastic Syndromes*/pathology
Myeloid-Derived Suppressor Cells*/metabolism
Humans ; Bone Marrow/metabolism ; Caspases ; CD8-Positive T-Lymphocytes/metabolism ; Cytokines/metabolism ; Hepatitis A Virus Cellular Receptor 2 ; Inflammasomes/metabolism ; Interleukin-18 ; NF-kappa B/metabolism ; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism
Czasopismo naukowe
Tytuł:
Endoplasmic reticulum stress mediates the myeloid-derived immune suppression associated with cancer and infectious disease.
Autorzy:
Lou X; Department of Clinical Laboratory, Songjiang Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 201600, China.
Gao D; Department of Infectious Disease, Songjiang Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 201600, China.
Yang L; Department of Clinical Laboratory, Songjiang Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 201600, China.
Wang Y; Department of Clinical Laboratory, Songjiang Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 201600, China.
Hou Y; Department of Clinical Laboratory, Songjiang Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 201600, China. .
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Źródło:
Journal of translational medicine [J Transl Med] 2023 Jan 02; Vol. 21 (1), pp. 1. Date of Electronic Publication: 2023 Jan 02.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Neoplasms*
Myeloid-Derived Suppressor Cells*
Communicable Diseases*/pathology
Humans ; Animals ; Mice ; Immunosuppression Therapy ; Endoplasmic Reticulum Stress ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
Notch1 signalling controls the differentiation and function of myeloid-derived suppressor cells in systemic lupus erythematosus.
Autorzy:
Li X; Department of Rheumatology and Immunology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China.
Fei F; Department of Rheumatology and Immunology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China.
Yao G; Department of Rheumatology and Immunology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China.
Yang X; Nanjing Drum Tower Hospital Clinical College of Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, China.
Geng L; Department of Rheumatology and Immunology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China.
Wang D; Department of Rheumatology and Immunology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China.
Gao Y; Department of Rheumatology and Immunology, The First People's Hospital of Nantong, Nantong, China.
Hou Y; The State Key Laboratory of Pharmaceutical Biotechnology, Division of Immunology, Medical School, Nanjing University, Nanjing, China.; Jiangsu Key Laboratory of Molecular Medicine, Nanjing, China.
Sun L; Department of Rheumatology and Immunology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China.; Nanjing Drum Tower Hospital Clinical College of Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, China.
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Źródło:
Immunology [Immunology] 2023 Jan; Vol. 168 (1), pp. 170-183. Date of Electronic Publication: 2022 Sep 17.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Myeloid-Derived Suppressor Cells*
Lupus Erythematosus, Systemic*
Animals ; Mice ; Platelet Aggregation Inhibitors/metabolism ; Platelet Aggregation Inhibitors/pharmacology ; Cell Differentiation
Czasopismo naukowe
Tytuł:
Adoptively Transferred in vitro-Generated Myeloid-Derived Suppressor Cells Improve T-Cell Function and Antigen-Specific Immunity after Traumatic Lung Injury.
Autorzy:
Kustermann M; Department of Pediatrics and Adolescent Medicine, University Medical Center Ulm, Ulm, Germany.
Dasari P; Department of Pediatrics and Adolescent Medicine, University Medical Center Ulm, Ulm, Germany.
Knape I; Department of Pediatrics and Adolescent Medicine, University Medical Center Ulm, Ulm, Germany.
Keltsch E; Department of Pediatrics and Adolescent Medicine, University Medical Center Ulm, Ulm, Germany.
Liu J; Department of Pediatrics and Adolescent Medicine, University Medical Center Ulm, Ulm, Germany.
Pflüger S; Department of Pediatrics and Adolescent Medicine, University Medical Center Ulm, Ulm, Germany.
Osen W; GMP & T Cell Therapy, German Cancer Research Center, Heidelberg, Germany.
Holzmann K; Genomic-Core Facility, University Ulm, Ulm, Germany.
Huber-Lang M; Institute of Experimental Trauma-Immunology, University Medical Center Ulm, Ulm, Germany.
Debatin KM; Department of Pediatrics and Adolescent Medicine, University Medical Center Ulm, Ulm, Germany.
Strauss G; Department of Pediatrics and Adolescent Medicine, University Medical Center Ulm, Ulm, Germany.
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Źródło:
Journal of innate immunity [J Innate Immun] 2023; Vol. 15 (1), pp. 78-95. Date of Electronic Publication: 2022 Jun 10.
Typ publikacji:
Journal Article
MeSH Terms:
Myeloid-Derived Suppressor Cells*
Thoracic Injuries*/metabolism
Lung Injury*/metabolism
Wounds, Nonpenetrating*/metabolism
Mice ; Animals ; Immunity, Innate
Czasopismo naukowe
Tytuł:
The Voltage-Gated Hv1 H Channel Is Expressed in Tumor-Infiltrating Myeloid-Derived Suppressor Cells.
Autorzy:
Cozzolino M; Department of Biophysics and Cell Biology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Gyöngyösi A; Department of Immunology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Korpos E; Department of Biophysics and Cell Biology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.; ELKH-DE Cell Biology and Signaling Research Group, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Gogolak P; Department of Immunology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Naseem MU; Department of Biophysics and Cell Biology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Kállai J; Department of Immunology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.; ELKH-DE Cell Biology and Signaling Research Group, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Lanyi A; Department of Immunology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Panyi G; Department of Biophysics and Cell Biology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Mar 25; Vol. 24 (7). Date of Electronic Publication: 2023 Mar 25.
Typ publikacji:
Journal Article
MeSH Terms:
Myeloid-Derived Suppressor Cells*/metabolism
Neoplasms*/metabolism
Animals ; Mice ; Cell Line ; Monocytes ; Myeloid Cells ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
Guadecitabine increases response to combined anti-CTLA-4 and anti-PD-1 treatment in mouse melanoma in vivo by controlling T-cells, myeloid derived suppressor and NK cells.
Autorzy:
Amaro A; IRCCS Ospedale Policlinico San Martino, Largo Rosanna Benzi, 10, 16132, Genova, Italy.
Reggiani F; IRCCS Ospedale Policlinico San Martino, Largo Rosanna Benzi, 10, 16132, Genova, Italy.
Fenoglio D; IRCCS Ospedale Policlinico San Martino, Largo Rosanna Benzi, 10, 16132, Genova, Italy.; Department of Internal Medicine, University of Genova, Genova, Italy.
Gangemi R; IRCCS Ospedale Policlinico San Martino, Largo Rosanna Benzi, 10, 16132, Genova, Italy.
Tosi A; Immunology and Molecular Oncology Diagnostics, Istituto Oncologico Veneto IRCCS, Padova, Italy.
Parodi A; IRCCS Ospedale Policlinico San Martino, Largo Rosanna Benzi, 10, 16132, Genova, Italy.
Banelli B; IRCCS Ospedale Policlinico San Martino, Largo Rosanna Benzi, 10, 16132, Genova, Italy.
Rigo V; IRCCS Ospedale Policlinico San Martino, Largo Rosanna Benzi, 10, 16132, Genova, Italy.
Mastracci L; IRCCS Ospedale Policlinico San Martino, Largo Rosanna Benzi, 10, 16132, Genova, Italy.
Grillo F; IRCCS Ospedale Policlinico San Martino, Largo Rosanna Benzi, 10, 16132, Genova, Italy.
Cereghetti A; Department of Dermatology, University of Zurich, University Hospital of Zurich, Zurich, Switzerland.
Tastanova A; Department of Dermatology, University of Zurich, University Hospital of Zurich, Zurich, Switzerland.
Ghosh A; Functional Genomics Center Zurich, University of Zurich and ETH Zurich, Zurich, Switzerland.
Sallustio F; Department of Interdisciplinary Medicine, University of Bari 'Aldo Moro', Bari, Italy.
Emionite L; IRCCS Ospedale Policlinico San Martino, Largo Rosanna Benzi, 10, 16132, Genova, Italy.
Daga A; IRCCS Ospedale Policlinico San Martino, Largo Rosanna Benzi, 10, 16132, Genova, Italy.
Altosole T; IRCCS Ospedale Policlinico San Martino, Largo Rosanna Benzi, 10, 16132, Genova, Italy.
Filaci G; IRCCS Ospedale Policlinico San Martino, Largo Rosanna Benzi, 10, 16132, Genova, Italy.; Department of Internal Medicine, University of Genova, Genova, Italy.
Rosato A; Immunology and Molecular Oncology Diagnostics, Istituto Oncologico Veneto IRCCS, Padova, Italy.; Department of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy.
Levesque M; Department of Dermatology, University of Zurich, University Hospital of Zurich, Zurich, Switzerland.
Maio M; University of Siena, Siena, Italy.
Pfeffer U; IRCCS Ospedale Policlinico San Martino, Largo Rosanna Benzi, 10, 16132, Genova, Italy. .
Croce M; IRCCS Ospedale Policlinico San Martino, Largo Rosanna Benzi, 10, 16132, Genova, Italy.
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Corporate Authors:
EPigenetic Immune-oncology Consortium Airc (EPICA) consortium
Źródło:
Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2023 Mar 18; Vol. 42 (1), pp. 67. Date of Electronic Publication: 2023 Mar 18.
Typ publikacji:
Journal Article
MeSH Terms:
Myeloid-Derived Suppressor Cells*
Melanoma*/pathology
Animals ; Mice ; CTLA-4 Antigen ; T-Lymphocytes, Regulatory ; Killer Cells, Natural/pathology ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
Tumor cell integrin β4 and tumor stroma E-/P-selectin cooperatively regulate tumor growth in vivo.
Autorzy:
Genduso S; Institute of Anatomy and Experimental Morphology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany.
Freytag V; Institute of Anatomy and Experimental Morphology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany.
Schetler D; Institute of Anatomy and Experimental Morphology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany.
Kirchner L; Institute of Anatomy and Experimental Morphology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany.
Schiecke A; Institute of Anatomy and Experimental Morphology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany.
Maar H; Institute of Anatomy and Experimental Morphology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany.; Institute of Anatomy I, Cancer Center Central Germany, Jena University Hospital, Teichgraben 7, 07743, Jena, Germany.
Wicklein D; Institute of Anatomy and Experimental Morphology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany.; Department of Anatomy and Cell Biology, University of Marburg, Robert-Koch-Strasse 8, 35037, Marburg, Germany.
Gebauer F; Institute of Anatomy and Experimental Morphology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany.; Department of General, Visceral and Thoracic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Department of General, Visceral and Thoracic Surgery, University Hospital Cologne, Kerpener Strasse 62, 50937, Cologne, Germany.
Bröker K; Institute of Anatomy and Experimental Morphology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany.
Stürken C; Institute of Anatomy and Experimental Morphology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany.; Faculty of Medicine, MSH Medical School Hamburg, Medical University, 20251, Hamburg, Germany.
Milde-Langosch K; Department of Gynecology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Oliveira-Ferrer L; Department of Gynecology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Ricklefs FL; Department of Neurosurgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Ewald F; Institute of Biochemistry and Signal Transduction, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Wolters-Eisfeld G; Department of General, Visceral and Thoracic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Department of Pediatric Hematology and Oncology, Research Institute Childrens' Cancer Center, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Riecken K; Research Department Cell and Gene Therapy, Department of Stem Cell Transplantation, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Unrau L; Institue of Experimental Immunology and Hepatology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Krause L; Institute of Medical Biometry and Epidemiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Bohnenberger H; Institute of Pathology, University Medical Center Göttingen, Robert-Koch-Strasse 40, 37075, Göttingen, Germany.
Offermann A; Institute of Pathology, University of Lübeck and University Medical Center Schleswig-Holstein, Campus Lübeck, Ratzeburger Allee 160, 23538, Lübeck, Germany.
Perner S; Institute of Pathology, University of Lübeck and University Medical Center Schleswig-Holstein, Campus Lübeck, Ratzeburger Allee 160, 23538, Lübeck, Germany.
Sebens S; Institute for Experimental Cancer Research, Kiel University (CAU) and University Medical Center Schleswig-Holstein, Campus Kiel, Arnold-Heller-Strasse 3, 24105, Kiel, Germany.
Lamszus K; Department of Neurosurgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Diehl L; Institue of Experimental Immunology and Hepatology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Linder S; Institute of Medical Microbiology, Virology and Hygiene, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Jücker M; Institute of Biochemistry and Signal Transduction, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Schumacher U; Institute of Anatomy and Experimental Morphology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany.; Medical School Berlin, Leipziger Platz 10, 10117, Berlin, Germany.
Lange T; Institute of Anatomy and Experimental Morphology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany. .; Institute of Anatomy I, Cancer Center Central Germany, Jena University Hospital, Teichgraben 7, 07743, Jena, Germany. .
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Źródło:
Journal of hematology & oncology [J Hematol Oncol] 2023 Mar 17; Vol. 16 (1), pp. 23. Date of Electronic Publication: 2023 Mar 17.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Integrin beta4*/metabolism
Myeloid-Derived Suppressor Cells*
Neoplasms*
Animals ; Humans ; Mice ; Cell Line, Tumor ; Chemokines ; Endothelial Cells/metabolism ; P-Selectin ; Tumor Microenvironment
Czasopismo naukowe

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