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Wyszukujesz frazę ""N-Formylmethionine"" wg kryterium: Temat


Tytuł:
Novel nano-carriers with N-formylmethionyl-leucyl-phenylalanine-modified liposomes improve effects of C16-angiopoietin 1 in acute animal model of multiple sclerosis.
Autorzy:
Fu XX; Institute of Anatomy and Cell Biology, Medical College, Zhejiang University, Hangzhou, PR China.; Institute of Human Anatomy, Histology and Embryology, Basic Medical College, Zhejiang Chinese Medical University, Hangzhou, PR China.
Qu H; Institute of Anatomy and Cell Biology, Medical College, Zhejiang University, Hangzhou, PR China.
Wang J; Department of Neurology, Sir Run Run Shaw Hospital, Medical College, Zhejiang University, Hangzhou, PR China.
Cai HY; Department of Neurology, Sir Run Run Shaw Hospital, Medical College, Zhejiang University, Hangzhou, PR China.
Jiang H; Department of Electrophysiology, Sir Run Run Shaw Hospital, Medical College, Zhejiang University, Hangzhou, PR China.
Chen HH; Medical Molecular Biology Laboratory, School of Medicine, Jinhua Polytechnic, Jinhua, PR China.
Han S; Institute of Anatomy and Cell Biology, Medical College, Zhejiang University, Hangzhou, PR China.
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Źródło:
Drug delivery [Drug Deliv] 2023 Dec; Vol. 30 (1), pp. 2241664.
Typ publikacji:
Journal Article
MeSH Terms:
Multiple Sclerosis*/drug therapy
Encephalomyelitis, Autoimmune, Experimental*/drug therapy
Encephalomyelitis, Autoimmune, Experimental*/pathology
Rats ; Animals ; Rabbits ; N-Formylmethionine Leucyl-Phenylalanine/chemistry ; N-Formylmethionine Leucyl-Phenylalanine/pharmacology ; Liposomes ; Angiopoietin-1/therapeutic use ; Rats, Inbred Lew ; Inflammation/drug therapy
Czasopismo naukowe
Tytuł:
Mitochondrial N-formyl methionine peptides contribute to exaggerated neutrophil activation in patients with COVID-19.
Autorzy:
Kuley R; Department of Medicine, Division of Rheumatology, University of Washington, Seattle, WA, USA.; Center for Life Sciences, Mahindra University, Hyderabad, India.
Duvvuri B; Department of Medicine, Division of Rheumatology, University of Washington, Seattle, WA, USA.
Wallin JJ; Biomarker Sciences, Gilead Sciences Inc, Foster City, CA, USA.
Bui N; Biomarker Sciences, Gilead Sciences Inc, Foster City, CA, USA.
Adona MV; Biomarker Sciences, Gilead Sciences Inc, Foster City, CA, USA.
O'Connor NG; Department of Medicine, University of Washington, Seattle, WA, USA.; Division of Pulmonary, Critical Care and Sleep Medicine, University of Washington, Seattle, WA, USA.
Sahi SK; Department of Medicine, University of Washington, Seattle, WA, USA.; Division of Pulmonary, Critical Care and Sleep Medicine, University of Washington, Seattle, WA, USA.
Stanaway IB; Department of Medicine, University of Washington, Seattle, WA, USA.; Division of Pulmonary, Critical Care and Sleep Medicine, University of Washington, Seattle, WA, USA.
Wurfel MM; Department of Medicine, University of Washington, Seattle, WA, USA.; Division of Pulmonary, Critical Care and Sleep Medicine, University of Washington, Seattle, WA, USA.
Morrell ED; Department of Medicine, University of Washington, Seattle, WA, USA.; Division of Pulmonary, Critical Care and Sleep Medicine, University of Washington, Seattle, WA, USA.
Liles WC; Department of Medicine, University of Washington, Seattle, WA, USA.; Sepsis Center of Research Excellence-UW (SCORE-UW), University of Washington, Seattle, WA, USA.
Bhatraju PK; Department of Medicine, University of Washington, Seattle, WA, USA.; Division of Pulmonary, Critical Care and Sleep Medicine, University of Washington, Seattle, WA, USA.; Sepsis Center of Research Excellence-UW (SCORE-UW), University of Washington, Seattle, WA, USA.
Lood C; Department of Medicine, Division of Rheumatology, University of Washington, Seattle, WA, USA.
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Źródło:
Virulence [Virulence] 2023 Dec; Vol. 14 (1), pp. 2218077.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:
Methionine*
COVID-19*
Humans ; Neutrophil Activation ; Peptides ; N-Formylmethionine/pharmacology ; Racemethionine ; Neutrophils ; Leukocyte L1 Antigen Complex
Czasopismo naukowe
Tytuł:
Method for simultaneous tracking of thousands of unlabeled cells within a transparent 3D matrix.
Autorzy:
Nette F; Fraunhofer Research and Development Center for Marine and Cellular Biotechnology, Lübeck, Germany.
Guerra de Souza AC; Fraunhofer Research and Development Center for Marine and Cellular Biotechnology, Lübeck, Germany.
Laskay T; Department of Infectious Diseases and Microbiology, University of Lübeck, Lübeck, Germany.
Ohms M; Research Department Virus Immunology, Leibniz Institute for Experimental Virology, Hamburg, Germany.
Dömer D; Department of Infectious Diseases and Microbiology, University of Lübeck, Lübeck, Germany.
Drömann D; Medical Clinic III Pneumology, University Medical Center Schleswig-Holstein, Lübeck, Germany.
Rapoport DH; Institute for Medical and Marine Biotechnology, University of Lübeck, Lübeck, Germany.
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Źródło:
PloS one [PLoS One] 2022 Jun 24; Vol. 17 (6), pp. e0270456. Date of Electronic Publication: 2022 Jun 24 (Print Publication: 2022).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Chemotaxis*
Neutrophils*
Collagen ; Humans ; Inflammation ; N-Formylmethionine Leucyl-Phenylalanine/pharmacology
Czasopismo naukowe
Tytuł:
Formyl-methionine as an N-degron of a eukaryotic N-end rule pathway.
Autorzy:
Kim JM; Department of Life Sciences, Pohang University of Science and Technology, Pohang, Gyeongbuk 37673, Republic of Korea.
Seok OH; Department of Life Sciences, Pohang University of Science and Technology, Pohang, Gyeongbuk 37673, Republic of Korea.
Ju S; Center for Theragnosis, Korea Institute of Science and Technology, Seoul 02792, Republic of Korea.; Department of Life Science and Research Institute for Natural Sciences, Hanyang University, Seoul 04763, Republic of Korea.
Heo JE; Department of Life Sciences, Pohang University of Science and Technology, Pohang, Gyeongbuk 37673, Republic of Korea.
Yeom J; Center for Theragnosis, Korea Institute of Science and Technology, Seoul 02792, Republic of Korea.; Division of Bio-Medical Science & Technology, KIST School, Korea University of Science and Technology, Seoul 02792, Republic of Korea.
Kim DS; Department of Life Sciences, Pohang University of Science and Technology, Pohang, Gyeongbuk 37673, Republic of Korea.
Yoo JY; Department of Life Sciences, Pohang University of Science and Technology, Pohang, Gyeongbuk 37673, Republic of Korea.
Varshavsky A; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
Lee C; Center for Theragnosis, Korea Institute of Science and Technology, Seoul 02792, Republic of Korea. .; Division of Bio-Medical Science & Technology, KIST School, Korea University of Science and Technology, Seoul 02792, Republic of Korea.; Department of Converging Science and Technology, KHU-KIST, Kyung Hee University, Seoul 02447, Republic of Korea.
Hwang CS; Department of Life Sciences, Pohang University of Science and Technology, Pohang, Gyeongbuk 37673, Republic of Korea. .
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Źródło:
Science (New York, N.Y.) [Science] 2018 Nov 30; Vol. 362 (6418). Date of Electronic Publication: 2018 Nov 08.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Proteolysis*
Amino Acids/*deficiency
Hydroxymethyl and Formyl Transferases/*metabolism
N-Formylmethionine/*metabolism
Saccharomyces cerevisiae/*metabolism
Saccharomyces cerevisiae Proteins/*metabolism
Azides/pharmacology ; Cold Temperature ; Cytosol/metabolism ; Metabolic Networks and Pathways ; Mitochondria/enzymology ; N-Formylmethionine/chemistry ; Peptide Elongation Factors/metabolism ; Phosphorylation ; Protein Serine-Threonine Kinases/metabolism ; Saccharomyces cerevisiae/drug effects ; Saccharomyces cerevisiae/enzymology ; Ubiquitin-Protein Ligases/metabolism ; Up-Regulation
Czasopismo naukowe
Tytuł:
The influence of extracellular tissue on neutrophil function and its possible linkage to inflammatory diseases.
Autorzy:
Kraus RF; Department of Anaesthesiology, University Medical Centre Regensburg, Regensburg, Germany.
Gruber MA; Department of Anaesthesiology, University Medical Centre Regensburg, Regensburg, Germany.
Kieninger M; Department of Anaesthesiology, University Medical Centre Regensburg, Regensburg, Germany.
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Źródło:
Immunity, inflammation and disease [Immun Inflamm Dis] 2021 Dec; Vol. 9 (4), pp. 1237-1251. Date of Electronic Publication: 2021 Jun 11.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Chemotaxis, Leukocyte*
Neutrophils*
Collagen ; N-Formylmethionine Leucyl-Phenylalanine ; Reactive Oxygen Species
Czasopismo naukowe
Tytuł:
The Differential Reactive Oxygen Species Production of Tear Neutrophils in Response to Various Stimuli In Vitro.
Autorzy:
Jin Y; School of Optometry and Vision Science, University of Waterloo, Waterloo, ON N2L 3G1, Canada.; Centre for Ocular Research and Education, University of Waterloo, Waterloo, ON N2L 3G1, Canada.
Dixon B; Department of Biology, University of Waterloo, Waterloo, ON N2L 3G1, Canada.
Jones L; School of Optometry and Vision Science, University of Waterloo, Waterloo, ON N2L 3G1, Canada.; Centre for Ocular Research and Education, University of Waterloo, Waterloo, ON N2L 3G1, Canada.
Gorbet M; School of Optometry and Vision Science, University of Waterloo, Waterloo, ON N2L 3G1, Canada.; Centre for Ocular Research and Education, University of Waterloo, Waterloo, ON N2L 3G1, Canada.; Department of Systems Design Engineering, University of Waterloo, Waterloo, ON N2L 3G1, Canada.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Nov 29; Vol. 22 (23). Date of Electronic Publication: 2021 Nov 29.
Typ publikacji:
Journal Article
MeSH Terms:
Neutrophils/*metabolism
Oxidative Stress/*drug effects
Reactive Oxygen Species/*metabolism
Tears/*drug effects
Tears/*metabolism
Adult ; Carcinogens/pharmacology ; Female ; Humans ; Lipopolysaccharides/pharmacology ; Male ; N-Formylmethionine Leucyl-Phenylalanine/pharmacology ; Neutrophils/cytology ; Neutrophils/drug effects ; Tears/cytology ; Tetradecanoylphorbol Acetate/pharmacology ; Young Adult
Czasopismo naukowe
Tytuł:
Exosomes mediate LTB4 release during neutrophil chemotaxis.
Autorzy:
Majumdar R; Laboratory of Cellular and Molecular Biology Center for Cancer Research, NCI, NIH, Bethesda, Maryland, United States of America.
Tavakoli Tameh A; Laboratory of Cellular and Molecular Biology Center for Cancer Research, NCI, NIH, Bethesda, Maryland, United States of America.
Arya SB; Department of Pharmacology, University of Michigan Medical School, Ann Arbor, United States of America.; Life Sciences Institute, University of Michigan, Ann Arbor, Michigan, United States of America.
Parent CA; Laboratory of Cellular and Molecular Biology Center for Cancer Research, NCI, NIH, Bethesda, Maryland, United States of America.; Department of Pharmacology, University of Michigan Medical School, Ann Arbor, United States of America.; Life Sciences Institute, University of Michigan, Ann Arbor, Michigan, United States of America.; Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, Michigan, United States of America.; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan, United States of America.
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Źródło:
PLoS biology [PLoS Biol] 2021 Jul 07; Vol. 19 (7), pp. e3001271. Date of Electronic Publication: 2021 Jul 07 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, N.I.H., Intramural
MeSH Terms:
Chemotaxis, Leukocyte/*physiology
Exosomes/*metabolism
Leukotriene B4/*metabolism
Neutrophils/*metabolism
Arachidonate 5-Lipoxygenase/metabolism ; Biological Transport ; Humans ; N-Formylmethionine Leucyl-Phenylalanine/administration & dosage ; Neutrophil Activation ; Receptors, Laminin/metabolism ; Ribosomal Proteins/metabolism ; Tetraspanin 30/metabolism
Czasopismo naukowe
Tytuł:
The Systemic Immune Response in COVID-19 Is Associated with a Shift to Formyl-Peptide Unresponsive Eosinophils.
Autorzy:
Koenderman L; Department of Respiratory Medicine, University Medical Center Utrecht, 3584CX Utrecht, The Netherlands.; Center for Translational Immunology, University Medical Center Utrecht, 3584CX Utrecht, The Netherlands.
Siemers MJ; Department of Respiratory Medicine, University Medical Center Utrecht, 3584CX Utrecht, The Netherlands.; Center for Translational Immunology, University Medical Center Utrecht, 3584CX Utrecht, The Netherlands.
van Aalst C; Department of Respiratory Medicine, University Medical Center Utrecht, 3584CX Utrecht, The Netherlands.; Center for Translational Immunology, University Medical Center Utrecht, 3584CX Utrecht, The Netherlands.
Bongers SH; Center for Translational Immunology, University Medical Center Utrecht, 3584CX Utrecht, The Netherlands.; Department of Trauma Surgery, University Medical Center Utrecht, 3584CX Utrecht, The Netherlands.
Spijkerman R; Department of Respiratory Medicine, University Medical Center Utrecht, 3584CX Utrecht, The Netherlands.; Center for Translational Immunology, University Medical Center Utrecht, 3584CX Utrecht, The Netherlands.
Bindels BJJ; Department of Respiratory Medicine, University Medical Center Utrecht, 3584CX Utrecht, The Netherlands.; Center for Translational Immunology, University Medical Center Utrecht, 3584CX Utrecht, The Netherlands.
Giustarini G; Department of Respiratory Medicine, University Medical Center Utrecht, 3584CX Utrecht, The Netherlands.; Center for Translational Immunology, University Medical Center Utrecht, 3584CX Utrecht, The Netherlands.
van Goor HMR; Department of Internal Medicine, University Medical Center Utrecht, 3584CX Utrecht, The Netherlands.
Kaasjager KAH; Department of Internal Medicine, University Medical Center Utrecht, 3584CX Utrecht, The Netherlands.
Vrisekoop N; Department of Respiratory Medicine, University Medical Center Utrecht, 3584CX Utrecht, The Netherlands.; Center for Translational Immunology, University Medical Center Utrecht, 3584CX Utrecht, The Netherlands.
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Źródło:
Cells [Cells] 2021 May 05; Vol. 10 (5). Date of Electronic Publication: 2021 May 05.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Immunity, Innate*
COVID-19/*immunology
Eosinophils/*immunology
N-Formylmethionine Leucyl-Phenylalanine/*metabolism
SARS-CoV-2/*immunology
Adult ; COVID-19/blood ; COVID-19/diagnosis ; COVID-19/virology ; COVID-19 Nucleic Acid Testing ; Case-Control Studies ; Cell Separation ; Cohort Studies ; Eosinophils/metabolism ; Flow Cytometry ; Healthy Volunteers ; Humans ; Leukocyte Count ; RNA, Viral/isolation & purification ; SARS-CoV-2/isolation & purification ; Severity of Illness Index
Czasopismo naukowe
Tytuł:
Formylated MHC Class Ib Binding Peptides Activate Both Human and Mouse Neutrophils Primarily through Formyl Peptide Receptor 1.
Autorzy:
Winther M; Department of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Holdfeldt A; Department of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Gabl M; Department of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Wang JM; Center for Cancer Research, Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America.
Forsman H; Department of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Dahlgren C; Department of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
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Źródło:
PloS one [PLoS One] 2016 Dec 01; Vol. 11 (12), pp. e0167529. Date of Electronic Publication: 2016 Dec 01 (Print Publication: 2016).
Typ publikacji:
Journal Article
MeSH Terms:
N-Formylmethionine Leucyl-Phenylalanine/*pharmacology
Neutrophils/*drug effects
Oligopeptides/*pharmacology
Receptors, Formyl Peptide/*immunology
Amino Acid Sequence ; Animals ; Gene Expression ; Humans ; Mice ; Mice, Inbred C57BL ; N-Formylmethionine Leucyl-Phenylalanine/chemical synthesis ; NADPH Oxidases/genetics ; NADPH Oxidases/immunology ; Neutrophil Activation/drug effects ; Neutrophils/cytology ; Neutrophils/immunology ; Oligopeptides/chemical synthesis ; Primary Cell Culture ; Receptors, Formyl Peptide/agonists ; Receptors, Formyl Peptide/genetics ; Superoxides/agonists ; Superoxides/immunology
Czasopismo naukowe
Tytuł:
Secoiridoid Glucosides and Anti-Inflammatory Constituents from the Stem Bark of Fraxinus chinensis .
Autorzy:
Chang HC; Department of Orthopaedics, MacKay Memorial Hospital, Taipei 10449, Taiwan.; Ph.D. Degree Program of Biomedical Science and Engineering, National Chiao Tung University, Hsinchu City 30068, Taiwan.
Wang SW; Department of Medicine, MacKay Medical College, New Taipei City 25242, Taiwan.; Graduate Institute of Natural Products, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.
Chen CY; Graduate Institute of Pharmaceutical Technology, Tajen University, Pingtung 90741, Taiwan.
Hwang TL; Graduate Institute of Natural Products, School of Traditional Chinese Medicine, College of Medicine, Chang Gung University, Taoyuan 33303, Taiwan.; Research Center for Food and Cosmetic Safety, Graduate Institute of Health Industry Technology, College of Human Ecology, Chang Gung University of Science and Technology, Taoyuan 33303, Taiwan.; Department of Anesthesiology, Chang Gung Memorial Hospital, Taoyuan 333, Taiwan.
Cheng MJ; Bioresource Collection and Research Center (BCRC), Food Industry Research and Development Institute (FIRDI), Hsinchu 30062, Taiwan.
Sung PJ; Graduate Institute of Natural Products, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.; National Museum of Marine Biology and Aquarium, Pingtung 94450, Taiwan.
Liao KW; Ph.D. Degree Program of Biomedical Science and Engineering, National Chiao Tung University, Hsinchu City 30068, Taiwan.; Institute of Molecular Medicine and Bioengineering, National Chiao Tung University, Hsinchu City 30068, Taiwan.
Chen JJ; Faculty of Pharmacy, School of Pharmaceutical Sciences, National Yang-Ming University, Taipei 11221, Taiwan.; Department of Medical Research, China Medical University Hospital, China Medical University, Taichung 40402, Taiwan.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2020 Dec 14; Vol. 25 (24). Date of Electronic Publication: 2020 Dec 14.
Typ publikacji:
Journal Article
MeSH Terms:
Anti-Inflammatory Agents/*pharmacology
Fraxinus/*chemistry
Gene Expression Regulation/*drug effects
Iridoid Glucosides/*pharmacology
Plant Bark/*chemistry
Animals ; Anti-Inflammatory Agents/chemistry ; Anti-Inflammatory Agents/classification ; Anti-Inflammatory Agents/isolation & purification ; Cytochalasin B/antagonists & inhibitors ; Cytochalasin B/pharmacology ; Gene Expression Regulation/immunology ; Humans ; Interleukin-6/genetics ; Interleukin-6/immunology ; Iridoid Glucosides/chemistry ; Iridoid Glucosides/classification ; Iridoid Glucosides/isolation & purification ; Kruppel-Like Factor 4 ; Kruppel-Like Transcription Factors/genetics ; Kruppel-Like Transcription Factors/immunology ; Leukocyte Elastase/immunology ; Leukocyte Elastase/metabolism ; Lipopolysaccharides/antagonists & inhibitors ; Lipopolysaccharides/pharmacology ; MAP Kinase Kinase 4/genetics ; MAP Kinase Kinase 4/immunology ; Mice ; Molecular Structure ; N-Formylmethionine Leucyl-Phenylalanine/antagonists & inhibitors ; N-Formylmethionine Leucyl-Phenylalanine/pharmacology ; NF-KappaB Inhibitor alpha/genetics ; NF-KappaB Inhibitor alpha/immunology ; Neutrophils/cytology ; Neutrophils/drug effects ; Neutrophils/immunology ; Nitric Oxide/antagonists & inhibitors ; Nitric Oxide/metabolism ; Plant Extracts/chemistry ; Primary Cell Culture ; RAW 264.7 Cells ; Structure-Activity Relationship ; Superoxides/antagonists & inhibitors ; Superoxides/metabolism ; Tumor Necrosis Factor-alpha/genetics ; Tumor Necrosis Factor-alpha/immunology ; p38 Mitogen-Activated Protein Kinases/genetics ; p38 Mitogen-Activated Protein Kinases/immunology
Czasopismo naukowe
Tytuł:
Dynamic Changes in the Ability to Release Neutrophil ExtraCellular Traps in the Course of Childhood Acute Leukemias.
Autorzy:
Ostafin M; Department of Laboratory Diagnostics and Clinical Immunology of the Developmental Age, Medical University of Warsaw, 63A Żwirki i Wigury St., 02-091 Warsaw, Poland.
Ciepiela O; Department of Laboratory Diagnostics and Clinical Immunology of the Developmental Age, Medical University of Warsaw, 63A Żwirki i Wigury St., 02-091 Warsaw, Poland.; Department of Laboratory Medicine, Medical University of Warsaw, 1A Banacha St., 02-097 Warsaw, Poland.
Pruchniak M; Department of Laboratory Diagnostics and Clinical Immunology of the Developmental Age, Medical University of Warsaw, 63A Żwirki i Wigury St., 02-091 Warsaw, Poland.
Wachowska M; Department of Laboratory Diagnostics and Clinical Immunology of the Developmental Age, Medical University of Warsaw, 63A Żwirki i Wigury St., 02-091 Warsaw, Poland.
Ulińska E; Department of Pediatric Hematology and Oncology, Medical University of Warsaw, 63A Żwirki i Wigury St., 02-091 Warsaw, Poland.
Mrówka P; Department of Biophysics and Human Physiology, Medical University of Warsaw, 5A Chalubinskiego St., 02-004 Warsaw, Poland.; Department of Experimental Hematology, Institute of Hematology and Transfusion Medicine, 15 Indiry Gandhi St., 02-776 Warsaw, Poland.
Głodkowska-Mrówka E; Department of Laboratory Diagnostics and Clinical Immunology of the Developmental Age, Medical University of Warsaw, 63A Żwirki i Wigury St., 02-091 Warsaw, Poland.; Department of Experimental Hematology, Institute of Hematology and Transfusion Medicine, 15 Indiry Gandhi St., 02-776 Warsaw, Poland.; Department of Hematological and Transfusion Immunology, Institute of Hematology and Transfusion Medicine, 15 Indiry Gandhi St., 02-776 Warsaw, Poland.
Demkow U; Department of Laboratory Diagnostics and Clinical Immunology of the Developmental Age, Medical University of Warsaw, 63A Żwirki i Wigury St., 02-091 Warsaw, Poland.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Jan 15; Vol. 22 (2). Date of Electronic Publication: 2021 Jan 15.
Typ publikacji:
Journal Article
MeSH Terms:
Extracellular Traps/*immunology
Immunity, Innate/*immunology
Leukemia/*immunology
Neutrophils/*immunology
Acute Disease ; Adolescent ; Calcium Ionophores/pharmacology ; Cells, Cultured ; Child ; Child, Preschool ; Humans ; Immunity, Innate/drug effects ; Infant ; Leukemia/blood ; Leukemia/drug therapy ; N-Formylmethionine Leucyl-Phenylalanine/pharmacology ; Neutrophils/drug effects ; Neutrophils/metabolism ; Tetradecanoylphorbol Acetate/pharmacology
Czasopismo naukowe
Tytuł:
N -Formylated Peptide Induces Increased Expression of Both Formyl Peptide Receptor 2 (Fpr2) and Toll-Like Receptor 9 (TLR9) in Schwannoma Cells-An In Vitro Model for Early Inflammatory Profiling of Schwann Cells.
Autorzy:
Korimová A; Cellular and Molecular Neurobiology Research Group, Department of Anatomy, Faculty of Medicine, Masaryk University, CZ-62500 Brno, Czech Republic.
Dubový P; Cellular and Molecular Neurobiology Research Group, Department of Anatomy, Faculty of Medicine, Masaryk University, CZ-62500 Brno, Czech Republic.
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Źródło:
Cells [Cells] 2020 Dec 11; Vol. 9 (12). Date of Electronic Publication: 2020 Dec 11.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
N-Formylmethionine Leucyl-Phenylalanine/*pharmacology
Receptors, Formyl Peptide/*metabolism
Toll-Like Receptor 9/*metabolism
Up-Regulation/*drug effects
Animals ; Cell Line, Tumor ; Chloroquine/pharmacology ; Inflammation/metabolism ; Inflammation/pathology ; Neurilemmoma/metabolism ; Neurilemmoma/pathology ; Rats ; Receptors, CCR2/genetics ; Receptors, CCR2/metabolism ; Receptors, CXCR4/genetics ; Receptors, CXCR4/metabolism ; Receptors, Formyl Peptide/antagonists & inhibitors ; Receptors, Formyl Peptide/genetics ; Schwann Cells/cytology ; Schwann Cells/drug effects ; Schwann Cells/metabolism ; Signal Transduction/drug effects ; Toll-Like Receptor 9/antagonists & inhibitors ; Toll-Like Receptor 9/genetics
Czasopismo naukowe
Tytuł:
Polymorphonuclear Cell Chemotaxis and Suicidal NETosis: Simultaneous Observation Using fMLP, PMA, H7, and Live Cell Imaging.
Autorzy:
Pai D; Department of Anesthesiology, University Medical Center Regensburg, Franz-Josef-Strauß-Allee 11, 93053 Regensburg, Germany.
Gruber M; Department of Anesthesiology, University Medical Center Regensburg, Franz-Josef-Strauß-Allee 11, 93053 Regensburg, Germany.
Pfaehler SM; Department of Anesthesiology, University Medical Center Regensburg, Franz-Josef-Strauß-Allee 11, 93053 Regensburg, Germany.
Bredthauer A; Department of Anesthesiology, University Medical Center Regensburg, Franz-Josef-Strauß-Allee 11, 93053 Regensburg, Germany.
Lehle K; Department of Cardiothoracic Surgery, University Medical Center Regensburg, Franz-Josef-Strauß-Allee 11, 93053 Regensburg, Germany.
Trabold B; Department of Anesthesiology, University Medical Center Regensburg, Franz-Josef-Strauß-Allee 11, 93053 Regensburg, Germany.
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Źródło:
Journal of immunology research [J Immunol Res] 2020 Aug 17; Vol. 2020, pp. 1415947. Date of Electronic Publication: 2020 Aug 17 (Print Publication: 2020).
Typ publikacji:
Journal Article
MeSH Terms:
Chemotaxis, Leukocyte/*immunology
Extracellular Traps/*immunology
Extracellular Traps/*metabolism
Neutrophils/*physiology
Chemotaxis, Leukocyte/drug effects ; Humans ; Molecular Imaging/methods ; N-Formylmethionine Leucyl-Phenylalanine ; Oxidation-Reduction ; Reactive Oxygen Species ; Tetradecanoylphorbol Acetate/pharmacology ; Time-Lapse Imaging
Czasopismo naukowe
Tytuł:
Promotion of experimental autoimmune encephalomyelitis upon neutrophil granulocytes' stimulation with formyl-methionyl-leucyl-phenylalanine (fMLP) peptide.
Autorzy:
Kilic AK; a Department of Neurology , Hacettepe University Medical Faculty , Ankara , Turkey .
Esendagli G
Sayat G
Talim B
Karabudak R
Kurne AT
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Źródło:
Autoimmunity [Autoimmunity] 2015; Vol. 48 (6), pp. 423-8.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Encephalomyelitis, Autoimmune, Experimental/*immunology
N-Formylmethionine Leucyl-Phenylalanine/*immunology
Neutrophils/*immunology
Animals ; Central Nervous System/immunology ; Central Nervous System/metabolism ; Central Nervous System/pathology ; Disease Models, Animal ; Disease Progression ; Encephalomyelitis, Autoimmune, Experimental/genetics ; Encephalomyelitis, Autoimmune, Experimental/pathology ; Female ; Immunization ; Immunophenotyping ; Inflammation Mediators/blood ; Inflammation Mediators/metabolism ; Mice ; N-Formylmethionine Leucyl-Phenylalanine/administration & dosage ; Neutrophil Infiltration ; Neutrophils/metabolism ; Spleen/immunology ; Spleen/pathology
Czasopismo naukowe
Tytuł:
Diosgenin inhibits superoxide generation in FMLP-activated mouse neutrophils via multiple pathways.
Autorzy:
Lin Y; Jiangsu Provincial Key Laboratory for TCM Evaluation and Translational Research, China Pharmaceutical University , Nanjing , P. R. China.
Jia R
Liu Y
Gao Y
Zeng X
Kou J
Yu B
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Źródło:
Free radical research [Free Radic Res] 2014 Dec; Vol. 48 (12), pp. 1485-93. Date of Electronic Publication: 2014 Oct 18.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Diosgenin/*pharmacology
N-Formylmethionine Leucyl-Phenylalanine/*pharmacology
Neutrophils/*drug effects
Neutrophils/*metabolism
Signal Transduction/*drug effects
Superoxides/*metabolism
Animals ; Male ; Mice ; Mice, Inbred ICR ; N-Formylmethionine Leucyl-Phenylalanine/administration & dosage
Czasopismo naukowe
Tytuł:
Immune profile of hyaluronic acid hydrogel polyethylene glycol crosslinked: An in vitro evaluation in human polymorphonuclear leukocytes.
Autorzy:
Marino F; Department of Medicine and Surgery, University of Insubria, Varese, Italy.
Cosentino M; Department of Medicine and Surgery, University of Insubria, Varese, Italy.
Legnaro M; Department of Medicine and Surgery, University of Insubria, Varese, Italy.
Luini A; Department of Medicine and Surgery, University of Insubria, Varese, Italy.
Sigova J; Department of Neonatology, Faculty of Continued Medical Education of Pirogov Russian National Research Medical University, Moscow, Russia.
Mocchi R; UB-CARE, Laboratories of the University of Pavia, Pavia, Italy.
Lotti T; Department of Dermatology, Guglielmo Marconi University, Rome, Italy.
Zerbinati N; Department of Medicine and Surgery, University of Insubria, Varese, Italy.
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Źródło:
Dermatologic therapy [Dermatol Ther] 2020 May; Vol. 33 (3), pp. e13388. Date of Electronic Publication: 2020 May 08.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Hyaluronic Acid*/pharmacology
Neutrophils*
Humans ; Hydrogels ; N-Formylmethionine Leucyl-Phenylalanine/pharmacology ; Polyethylene Glycols/pharmacology
Czasopismo naukowe
Tytuł:
Cell confinement reveals a branched-actin independent circuit for neutrophil polarity.
Autorzy:
Graziano BR; Cardiovascular Research Institute and Department of Biochemistry and Biophysics, University of California, San Francisco, California, United States of America.
Town JP; Cardiovascular Research Institute and Department of Biochemistry and Biophysics, University of California, San Francisco, California, United States of America.
Sitarska E; Cell Biology and Biophysics Unit, European Molecular Biology Laboratory, Heidelberg, Germany.
Nagy TL; Cardiovascular Research Institute and Department of Biochemistry and Biophysics, University of California, San Francisco, California, United States of America.
Fošnarič M; Laboratory of Clinical Biophysics, Faculty of Medicine, University of Ljubljana, Slovenia.
Penič S; Department of Theoretical Electrotechnics, Mathematics and Physics, Faculty of Electrical Engineering, University of Ljubljana, Slovenia.
Iglič A; Laboratory of Clinical Biophysics, Faculty of Medicine, University of Ljubljana, Slovenia.; Department of Theoretical Electrotechnics, Mathematics and Physics, Faculty of Electrical Engineering, University of Ljubljana, Slovenia.
Kralj-Iglič V; Faculty of Health Sciences, University of Ljubljana, Slovenia.
Gov NS; Department of Chemical and Biological Physics, Weizmann Institute, Rehovot, Israel.
Diz-Muñoz A; Cell Biology and Biophysics Unit, European Molecular Biology Laboratory, Heidelberg, Germany.
Weiner OD; Cardiovascular Research Institute and Department of Biochemistry and Biophysics, University of California, San Francisco, California, United States of America.
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Źródło:
PLoS biology [PLoS Biol] 2019 Oct 10; Vol. 17 (10), pp. e3000457. Date of Electronic Publication: 2019 Oct 10 (Print Publication: 2019).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Actin-Related Protein 2-3 Complex/*genetics
Actins/*genetics
Cell Polarity/*genetics
Chemotaxis/*genetics
Wiskott-Aldrich Syndrome Protein Family/*genetics
Actin-Related Protein 2-3 Complex/metabolism ; Actins/metabolism ; Biomechanical Phenomena ; CRISPR-Cas Systems ; Cell Adhesion/drug effects ; Cell Membrane/drug effects ; Cell Membrane/metabolism ; Cell Membrane/ultrastructure ; Cell Polarity/drug effects ; Chemotactic Factors/pharmacology ; Chemotaxis/drug effects ; Gene Editing ; Gene Expression Regulation ; HEK293 Cells ; HL-60 Cells ; Humans ; Microscopy, Atomic Force ; N-Formylmethionine Leucyl-Phenylalanine/pharmacology ; Pseudopodia/drug effects ; Pseudopodia/metabolism ; Pseudopodia/ultrastructure ; Signal Transduction ; Surface Properties ; Wiskott-Aldrich Syndrome Protein Family/deficiency
Czasopismo naukowe
Tytuł:
Neutrophil Functions in Immunodeficiency Due to DOCK8 Deficiency.
Autorzy:
Mandola AB; a Pediatric Immunology Clinic.; b Soroka University Medical Center.; c Faculty of Health Sciences , Ben-Gurion University of the Negev , Beer Sheva , Israel.
Levy J; a Pediatric Immunology Clinic.; b Soroka University Medical Center.; c Faculty of Health Sciences , Ben-Gurion University of the Negev , Beer Sheva , Israel.
Nahum A; a Pediatric Immunology Clinic.; b Soroka University Medical Center.; c Faculty of Health Sciences , Ben-Gurion University of the Negev , Beer Sheva , Israel.
Hadad N; b Soroka University Medical Center.; c Faculty of Health Sciences , Ben-Gurion University of the Negev , Beer Sheva , Israel.; d Infectious Disease Laboratory, Department of Clinical Biochemistry , Ben-Gurion University of the Negev , Beer Sheva , Israel.
Levy R; b Soroka University Medical Center.; c Faculty of Health Sciences , Ben-Gurion University of the Negev , Beer Sheva , Israel.; d Infectious Disease Laboratory, Department of Clinical Biochemistry , Ben-Gurion University of the Negev , Beer Sheva , Israel.
Rylova A; e Pediatric Immunology, Edmond and Lily Safra Children's Hospital, Sheba Medical Center , Tel Hashomer , Israel.
Simon AJ; e Pediatric Immunology, Edmond and Lily Safra Children's Hospital, Sheba Medical Center , Tel Hashomer , Israel.
Lev A; e Pediatric Immunology, Edmond and Lily Safra Children's Hospital, Sheba Medical Center , Tel Hashomer , Israel.
Somech R; e Pediatric Immunology, Edmond and Lily Safra Children's Hospital, Sheba Medical Center , Tel Hashomer , Israel.; f Sackler School of Medicine , Tel Aviv University , Tel Aviv , Israel.
Broides A; a Pediatric Immunology Clinic.; b Soroka University Medical Center.; c Faculty of Health Sciences , Ben-Gurion University of the Negev , Beer Sheva , Israel.
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Źródło:
Immunological investigations [Immunol Invest] 2019 May; Vol. 48 (4), pp. 431-439. Date of Electronic Publication: 2019 Jan 28.
Typ publikacji:
Journal Article
MeSH Terms:
Guanine Nucleotide Exchange Factors/*physiology
Immunologic Deficiency Syndromes/*immunology
Neutrophils/*physiology
Adolescent ; Cells, Cultured ; Chemotaxis ; Child ; Child, Preschool ; Codon, Nonsense ; Humans ; Immunologic Deficiency Syndromes/genetics ; N-Formylmethionine Leucyl-Phenylalanine/pharmacology ; Neutrophils/drug effects ; Phagocytosis ; Superoxides/metabolism ; Tetradecanoylphorbol Acetate/pharmacology
Czasopismo naukowe
Tytuł:
The major role of Listeria monocytogenes folic acid metabolism during infection is the generation of N-formylmethionine
Autorzy:
Ying Feng
Shannon K. Chang
Daniel A. Portnoy
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Temat:
folic acid
Listeria monocytogenes
N-formylmethionine
purine
tetrahydrofolate
Microbiology
QR1-502
Źródło:
mBio, Vol 14, Iss 5 (2023)
Opis pliku:
electronic resource
Relacje:
https://doaj.org/toc/2150-7511
Dostęp URL:
https://doaj.org/article/141b2593095144fc80533179ad2c9c31  Link otwiera się w nowym oknie
Czasopismo naukowe
Tytuł:
Lipid raft‑associated β‑adducin participates in neutrophil migration.
Autorzy:
Yang C; Institute of Genetics and Cytology, School of Life Sciences, Northeast Normal University, Changchun, Jilin 130024, P.R. China.
Sui Z; Hulunbeier Vocational College, Hulun Buir, Inner Mongolia 02100, P.R. China.
Xu T; Department of Rheumatology and Immunology, China‑Japan Union Hospital of Jilin University, Changchun, Jilin 130033, P.R. Chin.
Liu W; Institute of Genetics and Cytology, School of Life Sciences, Northeast Normal University, Changchun, Jilin 130024, P.R. China.
Wang X; Department of Bioscience, School of Life Science, Changchun Normal University, Changchun, Jilin 130032, P.R. China.
Zeng X; Institute of Genetics and Cytology, School of Life Sciences, Northeast Normal University, Changchun, Jilin 130024, P.R. China.
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Źródło:
Molecular medicine reports [Mol Med Rep] 2018 Aug; Vol. 18 (2), pp. 1353-1360. Date of Electronic Publication: 2018 May 31.
Typ publikacji:
Journal Article
MeSH Terms:
Cell Movement*
Cytoskeletal Proteins/*metabolism
Membrane Microdomains/*metabolism
Neutrophils/*metabolism
Adult ; Female ; HL-60 Cells ; Humans ; Male ; N-Formylmethionine Leucyl-Phenylalanine/analogs & derivatives ; N-Formylmethionine Leucyl-Phenylalanine/pharmacology ; Neutrophils/cytology
Czasopismo naukowe

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