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Wyświetlanie 1-20 z 2342135
Podgląd okładki
Tytuł :
Limit cycles in models of circular gene networks regulated by negative feedback loops.
Autorzy :
Likhoshvai VA; Department of Systems Biology, Institute of Cytology and Genetics, Siberian Branch RAS, Novosibirsk, Russia.
Golubyatnikov VP; Laboratory of Inverse Problems of Mathematical Physics, Sobolev Institute of Mathematics Siberian Branch RAS, Novosibirsk, Russia. .; Novosibirsk State University, Novosibirsk, Russia. .
Khlebodarova TM; Department of Systems Biology, Institute of Cytology and Genetics, Siberian Branch RAS, Novosibirsk, Russia.; Novosibirsk State University, Novosibirsk, Russia.
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Źródło :
BMC bioinformatics [BMC Bioinformatics] 2020 Sep 14; Vol. 21 (Suppl 11), pp. 255. Date of Electronic Publication: 2020 Sep 14.
Typ publikacji :
Journal Article
MeSH Terms :
Algorithms*
Feedback, Physiological*
Gene Regulatory Networks*
Models, Biological*
Gene Expression Regulation ; Metabolic Networks and Pathways ; Signal Transduction
Czasopismo naukowe
Szczegóły Pełny tekst Pełny tekst
Podgląd okładki
Tytuł :
Inferring a network from dynamical signals at its nodes.
Autorzy :
Weistuch C; Laufer Center for Physical and Quantitative Biology, Stony Brook University, Stony Brook, New York, USA.; Department of Applied Mathematics and Statistics, Stony Brook University, Stony Brook, New York, USA.
Agozzino L; Laufer Center for Physical and Quantitative Biology, Stony Brook University, Stony Brook, New York, USA.
Mujica-Parodi LR; Laufer Center for Physical and Quantitative Biology, Stony Brook University, Stony Brook, New York, USA.; Department of Physics and Astronomy, Stony Brook University, Stony Brook, New York, USA.; Department of Biomedical Engineering, Stony Brook University, Stony Brook, New York, USA.; Program in Neuroscience, Stony Brook University, Stony Brook, New York, USA.; Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Dill KA; Laufer Center for Physical and Quantitative Biology, Stony Brook University, Stony Brook, New York, USA.; Department of Physics and Astronomy, Stony Brook University, Stony Brook, New York, USA.; Department of Chemistry, Stony Brook University, Stony Brook, New York, USA.
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Źródło :
PLoS computational biology [PLoS Comput Biol] 2020 Nov 30; Vol. 16 (11), pp. e1008435. Date of Electronic Publication: 2020 Nov 30 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Neural Networks, Computer*
Action Potentials ; Algorithms ; Brain/cytology ; Brain/metabolism ; Gene Regulatory Networks ; Neurons/metabolism ; Proof of Concept Study
Czasopismo naukowe
Szczegóły Pełny tekst Pełny tekst
Podgląd okładki
Tytuł :
Robustness and lethality in multilayer biological molecular networks.
Autorzy :
Liu X; Key Laboratory of Imaging Processing and Intelligent Control, School of Artificial Intelligence and Automation, Huazhong University of Science and Technology, Wuhan, 430074, China. .
Maiorino E; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA.
Halu A; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA.
Glass K; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA.
Prasad RB; Genomics Diabetes and Endocrinology, Lund University Diabetes Centre, CRC, Malmö, SE, 20502, Sweden.
Loscalzo J; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA.
Gao J; Department of Computer Science, Rensselaer Polytechnic Institute, Troy, NY, 12180, USA. .
Sharma A; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA. .
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Źródło :
Nature communications [Nat Commun] 2020 Nov 27; Vol. 11 (1), pp. 6043. Date of Electronic Publication: 2020 Nov 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Gene Regulatory Networks*
Models, Biological*
Humans ; Metabolic Diseases/genetics ; Metabolic Networks and Pathways ; Neoplasms/genetics ; Numerical Analysis, Computer-Assisted
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
CGINet: graph convolutional network-based model for identifying chemical-gene interaction in an integrated multi-relational graph.
Autorzy :
Wang W; College of Computer, National University of Defense Technology, Changsha, 410073, China.
Yang X; College of Computer, National University of Defense Technology, Changsha, 410073, China.
Wu C; College of Computer, National University of Defense Technology, Changsha, 410073, China. .; State Key Laboratory of High-Performance Computing, National University of Defense Technology, Changsha, 410073, China. .
Yang C; College of Computer, National University of Defense Technology, Changsha, 410073, China.
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Źródło :
BMC bioinformatics [BMC Bioinformatics] 2020 Nov 26; Vol. 21 (1), pp. 544. Date of Electronic Publication: 2020 Nov 26.
Typ publikacji :
Journal Article
MeSH Terms :
Algorithms*
Epistasis, Genetic*
Models, Genetic*
Neural Networks, Computer*
Area Under Curve ; Gene Regulatory Networks ; Humans
Czasopismo naukowe
Szczegóły Pełny tekst Pełny tekst
Podgląd okładki
Tytuł :
netboxr: Automated discovery of biological process modules by network analysis in R.
Autorzy :
Liu EM; Department of Biostatistics and Epidemiology, Memorial Sloan Kettering Cancer Center, New York, NY, United States of America.
Luna A; Department of Cell Biology, Harvard Medical School, Boston, MA, United States of America.; cBio Center, Department of Data Sciences, Dana-Farber Cancer Institute, Boston, MA, United States of America.; Broad Institute of MIT and Harvard, Cambridge, MA, United States of America.
Dong G; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, United States of America.
Sander C; Department of Cell Biology, Harvard Medical School, Boston, MA, United States of America.; cBio Center, Department of Data Sciences, Dana-Farber Cancer Institute, Boston, MA, United States of America.; Broad Institute of MIT and Harvard, Cambridge, MA, United States of America.
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Źródło :
PloS one [PLoS One] 2020 Nov 02; Vol. 15 (11), pp. e0234669. Date of Electronic Publication: 2020 Nov 02 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Algorithms*
Gene Regulatory Networks*
Genome, Human*
Software*
Biomarkers, Tumor/*genetics
Genomics/*methods
Neoplasms/*genetics
Humans ; Metabolic Networks and Pathways ; Programming Languages
Czasopismo naukowe
Szczegóły Pełny tekst Pełny tekst
Podgląd okładki
Tytuł :
Learning and interpreting the gene regulatory grammar in a deep learning framework.
Autorzy :
Chen L; Department of Biological Sciences, Vanderbilt University, Nashville, TN, United States of America.
Capra JA; Department of Biological Sciences, Vanderbilt University, Nashville, TN, United States of America.; Vanderbilt Genetics Institute and Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, United States of America.; Department of Computer Science, Vanderbilt University, Nashville, TN, United States of America.
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Źródło :
PLoS computational biology [PLoS Comput Biol] 2020 Nov 02; Vol. 16 (11), pp. e1008334. Date of Electronic Publication: 2020 Nov 02 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Deep Learning*
Gene Regulatory Networks*
Genes, Regulator*
Animals ; Binding Sites/genetics ; Computational Biology ; Computer Simulation ; Databases, Genetic ; Enhancer Elements, Genetic ; Mice ; Models, Genetic ; Neural Networks, Computer ; Terminology as Topic ; Transcription Factors/metabolism
Czasopismo naukowe
Szczegóły Pełny tekst Pełny tekst
Podgląd okładki
Tytuł :
Using optimal control to understand complex metabolic pathways.
Autorzy :
Tsiantis N; Bioprocess Engineering Group, Spanish National Research Council, IIM-CSIC, C/Eduardo Cabello 6, 36208, Vigo, Spain.; Department of Chemical Engineering, University of Vigo, 36310, Vigo, Spain.
Banga JR; Bioprocess Engineering Group, Spanish National Research Council, IIM-CSIC, C/Eduardo Cabello 6, 36208, Vigo, Spain. .
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Źródło :
BMC bioinformatics [BMC Bioinformatics] 2020 Oct 21; Vol. 21 (1), pp. 472. Date of Electronic Publication: 2020 Oct 21.
Typ publikacji :
Journal Article
MeSH Terms :
Metabolic Networks and Pathways*
Computational Biology/*methods
Gene Regulatory Networks ; Saccharomyces cerevisiae/cytology ; Saccharomyces cerevisiae/metabolism ; Signal Transduction ; Transcriptome
Czasopismo naukowe
Szczegóły Pełny tekst Pełny tekst
Podgląd okładki
Tytuł :
Exploration into biomarker potential of region-specific brain gene co-expression networks.
Autorzy :
Hang Y; Department of Genetics and Biochemistry, Clemson University, Clemson, 29634, USA.
Aburidi M; Biomedical Data Science and Informatics Program, Clemson University, Clemson, 29634, USA.
Husain B; Biomedical Data Science and Informatics Program, Clemson University, Clemson, 29634, USA.
Hickman AR; Department of Genetics and Biochemistry, Clemson University, Clemson, 29634, USA.
Poehlman WL; Department of Genetics and Biochemistry, Clemson University, Clemson, 29634, USA.
Feltus FA; Department of Genetics and Biochemistry, Clemson University, Clemson, 29634, USA. .; Biomedical Data Science and Informatics Program, Clemson University, Clemson, 29634, USA. .; Center for Human Genetics, Clemson University, Clemson, 29634, USA. .
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Źródło :
Scientific reports [Sci Rep] 2020 Oct 13; Vol. 10 (1), pp. 17089. Date of Electronic Publication: 2020 Oct 13.
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Validation Study
MeSH Terms :
Gene Regulatory Networks*
Biomarkers/*metabolism
Brain/*metabolism
Biomarkers, Tumor/genetics ; Biomarkers, Tumor/metabolism ; Brain Neoplasms/genetics ; Brain Neoplasms/metabolism ; Databases, Genetic ; Gene Expression Profiling ; Genetic Markers ; Humans ; Models, Genetic ; Models, Neurological ; Mutation ; Neural Networks, Computer ; Tissue Distribution
Czasopismo naukowe
Szczegóły Pełny tekst Pełny tekst
Podgląd okładki
Tytuł :
Clustering analysis of tumor metabolic networks.
Autorzy :
Manipur I; National Research Council, Institute for High-Performance Computing and Networking, Via P. Castellino 111, Naples, 80131, Italy.
Granata I; National Research Council, Institute for High-Performance Computing and Networking, Via P. Castellino 111, Naples, 80131, Italy.
Maddalena L; National Research Council, Institute for High-Performance Computing and Networking, Via P. Castellino 111, Naples, 80131, Italy.
Guarracino MR; National Research Council, Institute for High-Performance Computing and Networking, Via P. Castellino 111, Naples, 80131, Italy. .; HSE - National Research University Higher School of Economics, LATNA Laboratory, 13 Rodionova Ulitsa, Nizhny Novgorod, Russia. .
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Źródło :
BMC bioinformatics [BMC Bioinformatics] 2020 Aug 21; Vol. 21 (Suppl 10), pp. 349. Date of Electronic Publication: 2020 Aug 21.
Typ publikacji :
Journal Article
MeSH Terms :
Metabolic Networks and Pathways*
Neoplasms/*metabolism
Algorithms ; Cluster Analysis ; Databases as Topic ; Gene Expression Regulation, Neoplastic ; Gene Regulatory Networks ; Humans ; Kidney/metabolism ; Neoplasms/genetics
Czasopismo naukowe
Szczegóły Pełny tekst Pełny tekst
Podgląd okładki
Tytuł :
Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases.
Autorzy :
Buljan M; Institute of Molecular Systems Biology, ETH Zurich, 8093 Zurich, Switzerland; Empa, Swiss Federal Laboratories for Materials Science and Technology, 9014 St. Gallen, Switzerland.
Ciuffa R; Institute of Molecular Systems Biology, ETH Zurich, 8093 Zurich, Switzerland.
van Drogen A; Institute of Molecular Systems Biology, ETH Zurich, 8093 Zurich, Switzerland.
Vichalkovski A; Institute of Molecular Systems Biology, ETH Zurich, 8093 Zurich, Switzerland.
Mehnert M; Institute of Molecular Systems Biology, ETH Zurich, 8093 Zurich, Switzerland.
Rosenberger G; Institute of Molecular Systems Biology, ETH Zurich, 8093 Zurich, Switzerland; Columbia University Department of Systems Biology, New York, NY 10032, USA.
Lee S; Institute of Molecular Systems Biology, ETH Zurich, 8093 Zurich, Switzerland.
Varjosalo M; Institute of Biotechnology, University of Helsinki, Helsinki 00014, Finland.
Pernas LE; Institute of Molecular Systems Biology, ETH Zurich, 8093 Zurich, Switzerland.
Spegg V; Department of Molecular Mechanisms of Disease, University of Zurich, 8057 Zurich, Switzerland.
Snijder B; Institute of Molecular Systems Biology, ETH Zurich, 8093 Zurich, Switzerland.
Aebersold R; Institute of Molecular Systems Biology, ETH Zurich, 8093 Zurich, Switzerland; Faculty of Science, University of Zurich, Zurich, Switzerland. Electronic address: .
Gstaiger M; Institute of Molecular Systems Biology, ETH Zurich, 8093 Zurich, Switzerland. Electronic address: .
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Źródło :
Molecular cell [Mol Cell] 2020 Aug 06; Vol. 79 (3), pp. 504-520.e9. Date of Electronic Publication: 2020 Jul 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Regulatory Networks*
Genetic Diseases, Inborn/*genetics
Neoplasms/*genetics
Protein Kinases/*genetics
Protein-Serine-Threonine Kinases/*genetics
Proto-Oncogene Proteins/*genetics
Computational Biology/methods ; Datasets as Topic ; Gene Expression Regulation ; Gene Ontology ; Genetic Diseases, Inborn/enzymology ; Genetic Diseases, Inborn/pathology ; Humans ; Metabolic Networks and Pathways/genetics ; Molecular Sequence Annotation ; Muscular Dystrophies/enzymology ; Muscular Dystrophies/genetics ; Muscular Dystrophies/pathology ; Neoplasms/enzymology ; Neoplasms/pathology ; Neurodegenerative Diseases/enzymology ; Neurodegenerative Diseases/genetics ; Neurodegenerative Diseases/pathology ; Protein Interaction Mapping/methods ; Protein Kinases/chemistry ; Protein Kinases/classification ; Protein Kinases/metabolism ; Protein-Serine-Threonine Kinases/chemistry ; Protein-Serine-Threonine Kinases/metabolism ; Proto-Oncogene Proteins/chemistry ; Proto-Oncogene Proteins/metabolism ; Signal Transduction
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
Integrated network modeling approach defines key metabolic responses of soil microbiomes to perturbations.
Autorzy :
McClure RS; Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA, USA.
Lee JY; Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA, USA.
Chowdhury TR; Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA, USA.; Department of Environmental Science and Technology, University of Maryland, College Park, MD, USA.
Bottos EM; Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA, USA.; Department of Biological Sciences, Thompson Rivers University, Kamloops, BC, Canada.
White RA 3rd; Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA, USA.; Department of Plant Pathology, Washington State University, Pullman, WA, USA.
Kim YM; Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA, USA.
Nicora CD; Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA, USA.
Metz TO; Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA, USA.
Hofmockel KS; Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA, USA.; Department of Ecology, Evolution and Organismal Biology, Iowa State University, Ames, IA, USA.
Jansson JK; Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA, USA.
Song HS; Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA, USA. .; Department of Biological Systems Engineering, University of Nebraska-Lincoln, Lincoln, NE, USA. .; Nebraska Food for Health Center, Department of Food Science and Technology, University of Nebraska-Lincoln, Lincoln, NE, USA. .
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Źródło :
Scientific reports [Sci Rep] 2020 Jul 02; Vol. 10 (1), pp. 10882. Date of Electronic Publication: 2020 Jul 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Metabolic Networks and Pathways*
Microbiota*/genetics
Soil Microbiology*
Bacterial Proteins/genetics ; Droughts ; Enzymes/genetics ; Gene Expression Regulation, Bacterial ; Gene Regulatory Networks ; Glycine/pharmacology ; Humidity ; Kansas ; Transcriptome
Czasopismo naukowe
Szczegóły Pełny tekst Pełny tekst
Podgląd okładki
Tytuł :
Measuring Cancer Hallmark Mediation of the TET1 Glioma Survival Effect with Linked Neural-Network Based Mediation Experiments.
Autorzy :
Luechtefeld T; Insilica LLC, 2736 Quarry Heights Way, Baltimore, MD, USA.
Lin N; Insilica LLC, 2736 Quarry Heights Way, Baltimore, MD, USA.
Paller C; Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD, USA.
Kuhns K; Department of Environmental Health and Engineering, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
Laterra JJ; Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD, USA.; Kennedy-Krieger Institute, Baltimore, MD, USA.
Bressler JP; Department of Environmental Health and Engineering, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA. .; Kennedy-Krieger Institute, Baltimore, MD, USA. .
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Źródło :
Scientific reports [Sci Rep] 2020 Jun 01; Vol. 10 (1), pp. 8886. Date of Electronic Publication: 2020 Jun 01.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Gene Regulatory Networks*
Brain Neoplasms/*mortality
Glioma/*mortality
Mixed Function Oxygenases/*genetics
Proto-Oncogene Proteins/*genetics
Brain Neoplasms/genetics ; Databases, Genetic ; Gene Expression Profiling ; Gene Expression Regulation, Neoplastic ; Gene Knockdown Techniques ; Glioma/genetics ; Humans ; Mutation ; Neural Networks, Computer ; Sequence Analysis, RNA ; Survival Analysis
Czasopismo naukowe
Szczegóły Pełny tekst Pełny tekst
Podgląd okładki
Tytuł :
Genetic buffering and potentiation in metabolism.
Autorzy :
Poyatos JF; Logic of Genomic Systems Lab (CNB-CSIC), Madrid, Spain.; Center for Genomics and Systems Biology (NYU), New York, United States of America.
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Źródło :
PLoS computational biology [PLoS Comput Biol] 2020 Sep 14; Vol. 16 (9), pp. e1008185. Date of Electronic Publication: 2020 Sep 14 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Metabolic Networks and Pathways*/genetics
Metabolic Networks and Pathways*/physiology
Mutation*/genetics
Mutation*/physiology
Gene Regulatory Networks/*genetics
Phenotype ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae/metabolism ; Systems Biology
Czasopismo naukowe
Szczegóły Pełny tekst Pełny tekst
Podgląd okładki
Tytuł :
A deep learning architecture for metabolic pathway prediction.
Autorzy :
Baranwal M; Department of Electrical Engineering and Computer Science, University of Michigan, Ann Arbor, MI 48109, USA.
Magner A; Department of Computer Science, University at Albany, SUNY, Albany, NY 12222, USA.
Elvati P; Department of Mechanical Engineering.
Saldinger J; Department of Mechanical Engineering.
Violi A; Department of Mechanical Engineering.; Department of Chemical Engineering and Biophysics, University of Michigan, Ann Arbor, MI 48109, USA.
Hero AO; Department of Electrical Engineering and Computer Science, University of Michigan, Ann Arbor, MI 48109, USA.
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Źródło :
Bioinformatics (Oxford, England) [Bioinformatics] 2020 Apr 15; Vol. 36 (8), pp. 2547-2553.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Deep Learning*
Neural Networks, Computer*
Machine Learning ; Metabolic Networks and Pathways ; Software
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
An efficient architecture for medical high-resolution images transmission in mobile telemedicine systems.
Autorzy :
Liu L; Department of Computer Science and Engineering, School of Information Science and Engineering, Yunnan University, Kunming 650091, China; Computer Technology Application Key Laboratory of Yunnan Province (Faculty of Information Engineering and Automation, Kunming University of Science and Technology), Kunming, 650500, China; Faculty of Information Engineering and Automation, Kunming University of Science and Technology, Kunming 650500, China.
Wang L; Department of Computer Science and Engineering, School of Information Science and Engineering, Yunnan University, Kunming 650091, China. Electronic address: .
Huang Q; Computer Technology Application Key Laboratory of Yunnan Province (Faculty of Information Engineering and Automation, Kunming University of Science and Technology), Kunming, 650500, China; Faculty of Information Engineering and Automation, Kunming University of Science and Technology, Kunming 650500, China.
Zhou L; Department of Computer Science and Engineering, School of Information Science and Engineering, Yunnan University, Kunming 650091, China.
Fu X; Computer Technology Application Key Laboratory of Yunnan Province (Faculty of Information Engineering and Automation, Kunming University of Science and Technology), Kunming, 650500, China; Faculty of Information Engineering and Automation, Kunming University of Science and Technology, Kunming 650500, China.
Liu L; Computer Technology Application Key Laboratory of Yunnan Province (Faculty of Information Engineering and Automation, Kunming University of Science and Technology), Kunming, 650500, China; Faculty of Information Engineering and Automation, Kunming University of Science and Technology, Kunming 650500, China.
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Źródło :
Computer methods and programs in biomedicine [Comput Methods Programs Biomed] 2020 Apr; Vol. 187, pp. 105088. Date of Electronic Publication: 2019 Nov 26.
Typ publikacji :
Journal Article
MeSH Terms :
Computer Communication Networks*
User-Computer Interface*
Image Processing, Computer-Assisted/*methods
Telemedicine/*instrumentation
Telemedicine/*methods
Algorithms ; Diagnostic Imaging ; Humans ; Information Storage and Retrieval ; Machine Learning ; Models, Statistical ; Neural Networks, Computer ; Radiology Information Systems ; Remote Consultation/instrumentation ; Software
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
Optimisation of cancer classification by machine learning generates an enriched list of candidate drug targets and biomarkers.
Autorzy :
Ramroach S; Department of Electrical and Computer Engineering, University of the West Indies, Saint Augustine, Trinidad and Tobago. .
Joshi A
John M
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Źródło :
Molecular omics [Mol Omics] 2020 Apr 01; Vol. 16 (2), pp. 113-125. Date of Electronic Publication: 2020 Feb 25.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Regulatory Networks*/drug effects
Biomarkers, Tumor/*genetics
Neoplasms/*classification
Antineoplastic Agents/pharmacology ; Antineoplastic Agents/therapeutic use ; Databases, Genetic ; Gene Expression Regulation, Neoplastic/drug effects ; Humans ; Machine Learning ; Molecular Targeted Therapy ; Neoplasms/drug therapy ; Neoplasms/genetics ; Neural Networks, Computer
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
Docosahexaenoic acid differentially modulates the cell cycle and metabolism- related genes in tumor and pre-malignant prostate cells.
Autorzy :
Tamarindo GH; Institute of Biology, University of Campinas, Campinas, SP, Brazil.
Góes RM; Institute of Biology, University of Campinas, Campinas, SP, Brazil; Department of Biology, Institute of Biosciences, Humanities and Exact Sciences, São Paulo State University, São José do Rio Preto, SP, Brazil. Electronic address: .
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Źródło :
Biochimica et biophysica acta. Molecular and cell biology of lipids [Biochim Biophys Acta Mol Cell Biol Lipids] 2020 Oct; Vol. 1865 (10), pp. 158766. Date of Electronic Publication: 2020 Jul 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Cycle/*genetics
Docosahexaenoic Acids/*metabolism
Metabolic Networks and Pathways/*genetics
Prostate/*metabolism
Prostatic Neoplasms/*genetics
Androgens/genetics ; Androgens/metabolism ; Apoptosis/genetics ; Cell Division/genetics ; Cell Line, Tumor ; Cell Proliferation/genetics ; Gene Regulatory Networks/genetics ; Humans ; Male ; Neoplasm Proteins/genetics ; Neoplasm Proteins/metabolism ; Prostate/pathology ; Prostatic Neoplasms/metabolism ; Prostatic Neoplasms/pathology
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
Mechanisms of indigo naturalis on treating ulcerative colitis explored by GEO gene chips combined with network pharmacology and molecular docking.
Autorzy :
Gu S; Traditional Chinese Medicine Department, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, 528 Zhang Heng Road, Pudong New area, Shanghai, 201203, China.
Xue Y; Shi's Center of Orthopedics and Traumatology, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China.
Gao Y; Traditional Chinese Medicine Department, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, 528 Zhang Heng Road, Pudong New area, Shanghai, 201203, China.
Shen S; Traditional Chinese Medicine Department, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, 528 Zhang Heng Road, Pudong New area, Shanghai, 201203, China.
Zhang Y; Traditional Chinese Medicine Department, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, 528 Zhang Heng Road, Pudong New area, Shanghai, 201203, China.
Chen K; Traditional Chinese Medicine Department, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, 528 Zhang Heng Road, Pudong New area, Shanghai, 201203, China.
Xue S; Digestive Endoscopy Center, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China.
Pan J; Digestive Endoscopy Center, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China.
Tang Y; Digestive Endoscopy Center, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China.
Zhu H; Emergency Department, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China.
Wu H; Traditional Chinese Medicine Department, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, 528 Zhang Heng Road, Pudong New area, Shanghai, 201203, China.
Dou D; Traditional Chinese Medicine Department, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, 528 Zhang Heng Road, Pudong New area, Shanghai, 201203, China. .
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Źródło :
Scientific reports [Sci Rep] 2020 Sep 16; Vol. 10 (1), pp. 15204. Date of Electronic Publication: 2020 Sep 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Colitis, Ulcerative/*genetics
Drugs, Chinese Herbal/*pharmacology
Gene Regulatory Networks/*drug effects
Protein Interaction Maps/*drug effects
Cell Differentiation/drug effects ; Colitis, Ulcerative/drug therapy ; Colitis, Ulcerative/metabolism ; Databases, Pharmaceutical ; Drugs, Chinese Herbal/chemistry ; Gene Expression Regulation/drug effects ; Humans ; Microarray Analysis ; Models, Molecular ; Molecular Docking Simulation ; Neural Networks, Computer ; Protein Conformation ; Th17 Cells
Czasopismo naukowe
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