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Wyszukujesz frazę ""NEUROBLASTOMA"" wg kryterium: Temat


Tytuł :
Biological features and clinical outcome in infant neuroblastoma: a multicenter experience in Beijing.
Autorzy :
Zhang S; Beijing Key Laboratory of Pediatric Hematology Oncology, National Key Discipline of Pediatrics, Ministry of Education, Key Laboratory of Major Diseases in Children, Hematology Oncology Center, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, 100045, China.
Zhang W; Beijing Tongren Hospital, Capital Medical University, Beijing, 100730, China.
Jin M; Beijing Key Laboratory of Pediatric Hematology Oncology, National Key Discipline of Pediatrics, Ministry of Education, Key Laboratory of Major Diseases in Children, Hematology Oncology Center, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, 100045, China.
Sun Q; Peking University First Hospital, Beijing, 100034, China.
Zhang Z; Capital Institute of Pediatrics, Beijing, 100020, China.
Qin H; Department of Surgical Oncology, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, 100045, China.
Su Y; Beijing Key Laboratory of Pediatric Hematology Oncology, National Key Discipline of Pediatrics, Ministry of Education, Key Laboratory of Major Diseases in Children, Hematology Oncology Center, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, 100045, China.
Zhi T; Beijing Tongren Hospital, Capital Medical University, Beijing, 100730, China.
Xie Y; Peking University First Hospital, Beijing, 100034, China.
Gao YX; Peking University First Hospital, Beijing, 100034, China.
Zhang X; Capital Institute of Pediatrics, Beijing, 100020, China.
Li L; Capital Institute of Pediatrics, Beijing, 100020, China.
Liu R; Capital Institute of Pediatrics, Beijing, 100020, China. .
Zhao W; Peking University First Hospital, Beijing, 100034, China. .
Wang H; Department of Surgical Oncology, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, 100045, China. .
Huang D; Beijing Tongren Hospital, Capital Medical University, Beijing, 100730, China. .
Ma X; Beijing Key Laboratory of Pediatric Hematology Oncology, National Key Discipline of Pediatrics, Ministry of Education, Key Laboratory of Major Diseases in Children, Hematology Oncology Center, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, 100045, China. .
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Źródło :
European journal of pediatrics [Eur J Pediatr] 2021 Jul; Vol. 180 (7), pp. 2055-2063. Date of Electronic Publication: 2021 Feb 13.
Typ publikacji :
Journal Article; Multicenter Study
MeSH Terms :
Neuroblastoma*/diagnosis
Neuroblastoma*/pathology
Neuroblastoma*/therapy
Child ; China/epidemiology ; Disease Progression ; Female ; Humans ; Infant ; Male ; Neoplasm Staging ; Prognosis ; Retrospective Studies
Czasopismo naukowe
Tytuł :
Combining inhibitors of Brd4 and cyclin-dependent kinase can decrease tumor growth in neuroblastoma with MYCN amplification.
Autorzy :
Wood L; Department of Surgery, Stanford University, Stanford, CA, USA.
Huang M; Department of Pediatrics, Stanford University, Stanford, USA.
Zeki J; Department of Surgery, Stanford University, Stanford, CA, USA.
Gong M; Department of Surgery, Stanford University, Stanford, CA, USA.
Taylor J; Department of Surgery, Stanford University, Stanford, CA, USA.
Shimada H; Department of Pathology, Stanford University, Stanford, CA, USA.
Chiu B; Department of Surgery, Stanford University, Stanford, CA, USA. Electronic address: .
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Źródło :
Journal of pediatric surgery [J Pediatr Surg] 2021 Jul; Vol. 56 (7), pp. 1199-1202. Date of Electronic Publication: 2021 Mar 26.
Typ publikacji :
Journal Article
MeSH Terms :
Cyclin-Dependent Kinases*
Neuroblastoma*/drug therapy
Neuroblastoma*/genetics
Animals ; Cell Cycle Proteins/genetics ; Cell Line, Tumor ; Gene Expression Regulation, Neoplastic ; Humans ; Mice ; N-Myc Proto-Oncogene Protein/genetics ; N-Myc Proto-Oncogene Protein/metabolism ; Nuclear Proteins/genetics ; Nuclear Proteins/metabolism ; Transcription Factors
Czasopismo naukowe
Tytuł :
Clonal evidence for the development of neuroblastoma with extensive copy-neutral loss of heterozygosity arising in a mature teratoma.
Autorzy :
Ono R; Department of Pediatrics, St. Luke's International Hospital, Tokyo, Japan.
Ueno H; Department of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Yoshida K; Department of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Takahashi S; Department of Pediatrics, St. Luke's International Hospital, Tokyo, Japan.; Department of Pediatrics, Japanese Red Cross Narita Hospital, Chiba, Japan.
Yoshihara H; Department of Pediatrics, St. Luke's International Hospital, Tokyo, Japan.
Nozaki T; Department of Diagnostic Radiology, St. Luke's International Hospital, Tokyo, Japan.
Suzuki K; Department of Pathology, St. Luke's International Hospital, Tokyo, Japan.
Nakazawa A; Department of Clinical Research, Saitama Children's Medical Center, Saitama, Japan.
Saiki R; Department of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Seki M; Department of Pediatrics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Takita J; Department of Pediatrics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.; Department of Pediatrics, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Ogawa S; Department of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Manabe A; Department of Pediatrics, St. Luke's International Hospital, Tokyo, Japan.; Department of Pediatrics, Hokkaido University Graduate School of Medicine, Sapporo, Japan.
Hasegawa D; Department of Pediatrics, St. Luke's International Hospital, Tokyo, Japan.
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Źródło :
Cancer science [Cancer Sci] 2021 Jul; Vol. 112 (7), pp. 2921-2927. Date of Electronic Publication: 2021 May 06.
Typ publikacji :
Case Reports
MeSH Terms :
Germ-Line Mutation*
Loss of Heterozygosity*
Neoplasms, Multiple Primary/*genetics
Neuroblastoma/*genetics
Ovarian Neoplasms/*genetics
Teratoma/*genetics
Adolescent ; F-Box Proteins/genetics ; Female ; Homozygote ; Humans ; Neoplasms, Multiple Primary/drug therapy ; Neoplasms, Multiple Primary/pathology ; Neuroblastoma/drug therapy ; Neuroblastoma/pathology ; Ovarian Neoplasms/drug therapy ; Ovarian Neoplasms/pathology ; Retinoblastoma-Like Protein p130/genetics ; Teratoma/drug therapy ; Teratoma/pathology ; Whole Exome Sequencing
Raport
Tytuł :
Feasibility and Therapeutic Potential of Combined Peptide Receptor Radionuclide Therapy With Intensive Chemotherapy for Pediatric Patients With Relapsed or Refractory Metastatic Neuroblastoma.
Autorzy :
Fathpour G
Jafari E; The Persian Gulf Nuclear Medicine Research Center, Department of Molecular Imaging and Radionuclide Therapy, Bushehr Medical University Hospital, Bushehr University of Medical Sciences, Bushehr.
Hashemi A; From the Division of Hematology/Oncology, Department of Pediatrics, School of Medicine.
Dadgar H; Cancer Research Center, Razavi Hospital, Imam Reza International University, Mashhad.
Shahriari M; Hematology Research Center, Shiraz University of Medical Sciences, Shiraz.
Zareifar S; Hematology Research Center, Shiraz University of Medical Sciences, Shiraz.
Jenabzade AR; Department of Pediatric Hematology and Oncology, School of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Vali R; Department of Diagnostic Imaging, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.
Ahmadzadehfar H; Department of Nuclear Medicine, Klinikum Westfalen, Dortmund, Germany.
Assadi M; The Persian Gulf Nuclear Medicine Research Center, Department of Molecular Imaging and Radionuclide Therapy, Bushehr Medical University Hospital, Bushehr University of Medical Sciences, Bushehr.
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Źródło :
Clinical nuclear medicine [Clin Nucl Med] 2021 Jul 01; Vol. 46 (7), pp. 540-548.
Typ publikacji :
Journal Article
MeSH Terms :
Iodine Radioisotopes/*therapeutic use
Neuroblastoma/*pathology
Neuroblastoma/*therapy
Receptors, Peptide/*metabolism
Child ; Child, Preschool ; Combined Modality Therapy ; Coordination Complexes ; Feasibility Studies ; Female ; Humans ; Male ; Middle Aged ; Neuroblastoma/drug therapy ; Neuroblastoma/radiotherapy ; Octreotide/analogs & derivatives ; Organometallic Compounds ; Positron Emission Tomography Computed Tomography ; Receptors, Somatostatin/metabolism ; Recurrence ; Treatment Failure
Czasopismo naukowe
Tytuł :
A Novel pH-Sensitive Multifunctional DNA Nanomedicine: An Enhanced and Harmless GD2 Aptamer-Mediated Strategy for Guiding Neuroblastoma Antitumor Therapy.
Autorzy :
Zhang L; Department of Neonatology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, People's Republic of China.; Shaanxi Institute of Pediatric Diseases, Affiliated Children's Hospital of Xi'an Jiaotong University, Xi'an, People's Republic of China.
Wang M; Department of Emergency Surgery, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi, People's Republic of China.
Zhu Z; Department of Hepatobiliary Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710061, People's Republic of China.
Ding C; Department of Neonatology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, People's Republic of China.
Chen S; Department of Neonatology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, People's Republic of China.
Wu H; Shaanxi Institute of Pediatric Diseases, Affiliated Children's Hospital of Xi'an Jiaotong University, Xi'an, People's Republic of China.
Yang Y; Shaanxi Institute of Pediatric Diseases, Affiliated Children's Hospital of Xi'an Jiaotong University, Xi'an, People's Republic of China.
Che F; Shaanxi Institute of Pediatric Diseases, Affiliated Children's Hospital of Xi'an Jiaotong University, Xi'an, People's Republic of China.
Li Q; Department of Clinical Laboratory, Affiliated Children's Hospital of Xi'an Jiaotong University, Xi'an, People's Republic of China.
Li H; Department of Neonatology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, People's Republic of China.; Department of Neonatology, Affiliated Children's Hospital of Xi'an Jiaotong University, Xi'an, People's Republic of China.
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Źródło :
International journal of nanomedicine [Int J Nanomedicine] 2021 May 10; Vol. 16, pp. 3217-3240. Date of Electronic Publication: 2021 May 10 (Print Publication: 2021).
Typ publikacji :
Journal Article
MeSH Terms :
Nanomedicine*
Antineoplastic Agents/*therapeutic use
Aptamers, Nucleotide/*chemistry
DNA/*chemistry
Neuroblastoma/*drug therapy
Animals ; Antineoplastic Agents/pharmacology ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Disease Models, Animal ; Doxorubicin/pharmacology ; Doxorubicin/therapeutic use ; Drug Delivery Systems ; Female ; Humans ; Hydrogen-Ion Concentration ; Mice, Inbred BALB C ; Molecular Docking Simulation ; Neuroblastoma/genetics ; Neuroblastoma/pathology ; SELEX Aptamer Technique ; Transcriptome/genetics ; Tumor Microenvironment/drug effects
Czasopismo naukowe
Tytuł :
Improving Exposure Using Thoracoscopy for Apical Thoracic Neuroblastoma Encasing the Subclavian Vessels.
Autorzy :
Abdelhafeez AH; Department of Surgery, St. Jude Children's Research Hospital, Memphis, USA.; Division of Pediatric Surgery, Department of Surgery, University of Tennessee Health Sciences Center, Memphis, USA.
Mansfield S; Department of Surgery, St. Jude Children's Research Hospital, Memphis, USA.
Talbot L; Department of Surgery, St. Jude Children's Research Hospital, Memphis, USA.; Division of Pediatric Surgery, Department of Surgery, University of Tennessee Health Sciences Center, Memphis, USA.
Murphy AJ; Department of Surgery, St. Jude Children's Research Hospital, Memphis, USA.; Division of Pediatric Surgery, Department of Surgery, University of Tennessee Health Sciences Center, Memphis, USA.
Davidoff AM; Department of Surgery, St. Jude Children's Research Hospital, Memphis, USA.; Division of Pediatric Surgery, Department of Surgery, University of Tennessee Health Sciences Center, Memphis, USA.
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Źródło :
Journal of laparoendoscopic & advanced surgical techniques. Part A [J Laparoendosc Adv Surg Tech A] 2021 May; Vol. 31 (5), pp. 589-593. Date of Electronic Publication: 2021 Feb 16.
Typ publikacji :
Journal Article; Video-Audio Media
MeSH Terms :
Neuroblastoma/*surgery
Subclavian Artery/*surgery
Thoracic Neoplasms/*surgery
Thoracoscopy/*methods
Child, Preschool ; Female ; Humans ; Infant ; Male ; Neoplasm Invasiveness ; Neuroblastoma/diagnostic imaging ; Neuroblastoma/pathology ; Retrospective Studies ; Subclavian Artery/diagnostic imaging ; Thoracic Neoplasms/diagnostic imaging ; Thoracic Neoplasms/pathology ; Tomography, X-Ray Computed ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Radiogenomics of neuroblastoma in pediatric patients: CT-based radiomics signature in predicting MYCN amplification.
Autorzy :
Wu H; Department of Radiology, Xinhua Hospital affiliated of Shanghai Jiao Tong University School of Medicine, No.1665 Kongjiang Road, Yangpu District, Shanghai City, 200082, China.
Wu C; Department of Radiology, Xinhua Hospital affiliated of Shanghai Jiao Tong University School of Medicine, No.1665 Kongjiang Road, Yangpu District, Shanghai City, 200082, China.
Zheng H; Department of Radiology, Xinhua Hospital affiliated of Shanghai Jiao Tong University School of Medicine, No.1665 Kongjiang Road, Yangpu District, Shanghai City, 200082, China.
Wang L; Department of Radiology, Xinhua Hospital affiliated of Shanghai Jiao Tong University School of Medicine, No.1665 Kongjiang Road, Yangpu District, Shanghai City, 200082, China.
Guan W; Department of Pathology, Xinhua Hospital affiliated of Shanghai Jiao Tong University School of Medicine, No.1665 Kongjiang Road, Yangpu District, Shanghai City, 200082, China.
Duan S; GE Healthcare, Pudong New Town, No.1, Huatuo Road, Shanghai, 210000, China.
Wang D; Department of Radiology, Xinhua Hospital affiliated of Shanghai Jiao Tong University School of Medicine, No.1665 Kongjiang Road, Yangpu District, Shanghai City, 200082, China. .
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Źródło :
European radiology [Eur Radiol] 2021 May; Vol. 31 (5), pp. 3080-3089. Date of Electronic Publication: 2020 Oct 29.
Typ publikacji :
Journal Article
MeSH Terms :
Neuroblastoma*/diagnostic imaging
Neuroblastoma*/genetics
Tomography, X-Ray Computed*
Child ; Humans ; N-Myc Proto-Oncogene Protein/genetics ; Nomograms ; ROC Curve
Czasopismo naukowe
Tytuł :
Neuroblastoma: the association of anatomical tumour site, molecular biology and patient outcomes.
Autorzy :
Salim A; Department of Paediatric Surgery, Alder Hey Children's Hospital NHS Foundation Trust, Liverpool, UK.
Raitio A; Department of Paediatric Surgery, Alder Hey Children's Hospital NHS Foundation Trust, Liverpool, UK.; Department of Paediatric Surgery, Turku University Hospital and The University of Turku, Turku, Finland.
Pizer B; Department of Oncology, Alder Hey Children's Hospital NHS Foundation Trust, Liverpool, UK.
Mullassery D; Department of Paediatric Surgery, Alder Hey Children's Hospital NHS Foundation Trust, Liverpool, UK.
Losty PD; Department of Paediatric Surgery, Alder Hey Children's Hospital NHS Foundation Trust, Liverpool, UK.; Institute of Child Health, School of Health and Life Sciences, -The University of Liverpool, Liverpool, UK.
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Źródło :
ANZ journal of surgery [ANZ J Surg] 2021 May; Vol. 91 (5), pp. 1000-1004. Date of Electronic Publication: 2021 Jan 28.
Typ publikacji :
Journal Article
MeSH Terms :
Neuroblastoma*/diagnostic imaging
Neuroblastoma*/genetics
Humans ; Infant ; Kaplan-Meier Estimate ; Molecular Biology ; N-Myc Proto-Oncogene Protein/genetics ; Prognosis
Czasopismo naukowe
Tytuł :
Novel reporters of mitochondria-associated membranes (MAM), MAMtrackers, demonstrate MAM disruption as a common pathological feature in amyotrophic lateral sclerosis.
Autorzy :
Sakai S; Department of Neuroscience and Pathobiology, Research Institute of Environmental Medicine, Nagoya University, Nagoya, Japan.; Department of Neuroscience and Pathobiology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Watanabe S; Department of Neuroscience and Pathobiology, Research Institute of Environmental Medicine, Nagoya University, Nagoya, Japan.; Department of Neuroscience and Pathobiology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Komine O; Department of Neuroscience and Pathobiology, Research Institute of Environmental Medicine, Nagoya University, Nagoya, Japan.; Department of Neuroscience and Pathobiology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Sobue A; Department of Neuroscience and Pathobiology, Research Institute of Environmental Medicine, Nagoya University, Nagoya, Japan.; Department of Neuroscience and Pathobiology, Nagoya University Graduate School of Medicine, Nagoya, Japan.; Medical Interactive Research and Academia Industry Collaboration Center, Research Institute of Environmental Medicine, Nagoya University, Nagoya, Japan.
Yamanaka K; Department of Neuroscience and Pathobiology, Research Institute of Environmental Medicine, Nagoya University, Nagoya, Japan.; Department of Neuroscience and Pathobiology, Nagoya University Graduate School of Medicine, Nagoya, Japan.; Institute for Glyco-core Research (iGCORE), Nagoya University, Nagoya, Japan.
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Źródło :
FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2021 Jul; Vol. 35 (7), pp. e21688.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Mutation*
Amyotrophic Lateral Sclerosis/*pathology
Mitochondria/*pathology
Mitochondrial Membranes/*pathology
Mitochondrial Proteins/*metabolism
Neuroblastoma/*pathology
Amyotrophic Lateral Sclerosis/etiology ; Amyotrophic Lateral Sclerosis/metabolism ; Animals ; Humans ; Mice ; Mitochondria/metabolism ; Mitochondrial Membranes/metabolism ; Mitochondrial Proteins/genetics ; Neuroblastoma/genetics ; Neuroblastoma/metabolism
Czasopismo naukowe
Tytuł :
Anti-relapse effect of trametinib on a local minimal residual disease neuroblastoma mouse model.
Autorzy :
Togashi Y; Department of Pediatric Surgery, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan. Electronic address: .
Tanaka T; Department of Pediatric Surgery, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan.
Takemoto M; Department of Pediatric Surgery, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan.
Takeuchi Y; Department of Pediatric Surgery, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan.
Higashi M; Department of Pediatric Surgery, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan.
Fumino S; Department of Pediatric Surgery, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan.
Tajiri T; Department of Pediatric Surgery, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan.
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Źródło :
Journal of pediatric surgery [J Pediatr Surg] 2021 Jul; Vol. 56 (7), pp. 1233-1239. Date of Electronic Publication: 2021 Mar 26.
Typ publikacji :
Journal Article
MeSH Terms :
Neoplasm Recurrence, Local*/drug therapy
Neuroblastoma*/drug therapy
Animals ; Cell Line, Tumor ; Mice ; Mice, Nude ; Neoplasm, Residual ; Protein Kinase Inhibitors ; Pyridones/pharmacology ; Pyridones/therapeutic use ; Pyrimidinones/therapeutic use
Czasopismo naukowe
Tytuł :
In vivo imaging of neuroblastomas using GD2-targeting graphene quantum dots.
Autorzy :
Lin YS; Department of Chemical Engineering and Materials Science, Yuan Ze University, Chung-Li, Taoyuan, Taiwan.
Chen Y; Department of Chemical Engineering and Materials Science, Yuan Ze University, Chung-Li, Taoyuan, Taiwan; Graduate Institute of Medicine, Yuan Ze University, Chung-Li, Taoyuan, Taiwan; Department of Surgery, Far Eastern Memorial Hospital, Pan-Chiao, New Taipei, Taiwan.
Tsai YH; Department of Chemical Engineering and Materials Science, Yuan Ze University, Chung-Li, Taoyuan, Taiwan; Department of Surgery, Far Eastern Memorial Hospital, Pan-Chiao, New Taipei, Taiwan; Department of Materials and Textiles, Oriental Institute of Technology, Pan-Chiao, New Taipei, Taiwan.
Tseng SH; Department of Surgery, Far Eastern Memorial Hospital, Pan-Chiao, New Taipei, Taiwan; Department of Surgery, National Taiwan University Hospital, Taipei, Taiwan. Electronic address: .
Lin KS; Department of Chemical Engineering and Materials Science, Yuan Ze University, Chung-Li, Taoyuan, Taiwan. Electronic address: .
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Źródło :
Journal of pediatric surgery [J Pediatr Surg] 2021 Jul; Vol. 56 (7), pp. 1227-1232. Date of Electronic Publication: 2021 Mar 24.
Typ publikacji :
Journal Article
MeSH Terms :
Graphite*
Neuroblastoma*/diagnostic imaging
Quantum Dots*
Animals ; Child ; Diagnostic Imaging ; Humans ; Mice
Czasopismo naukowe
Tytuł :
Efficacy of a Three Drug-Based Therapy for Neuroblastoma in Mice.
Autorzy :
Garbati P; IRCCS Ospedale Policlinico San Martino, 16132 Genova, Italy.
Barbieri R; IRCCS Ospedale Policlinico San Martino, 16132 Genova, Italy.
Calderoni M; Department of Experimental Medicine (DIMES), University of Genova, 16132 Genova, Italy.
Baldini F; Department of Experimental Medicine (DIMES), University of Genova, 16132 Genova, Italy.
Nizzari M; Department of Experimental Medicine (DIMES), University of Genova, 16132 Genova, Italy.
Modesto P; National Reference Center for Veterinary and Comparative Oncology-Veterinary Medical Research Institute for Piemonte, Liguria and Valle d'Aosta, 10154 Torino, Italy.
Florio T; IRCCS Ospedale Policlinico San Martino, 16132 Genova, Italy.; Department of Internal Medicine and Centre of Excellence for Biomedical Research, University of Genova, 16132 Genova, Italy.
Pagano A; IRCCS Ospedale Policlinico San Martino, 16132 Genova, Italy.; Department of Experimental Medicine (DIMES), University of Genova, 16132 Genova, Italy.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jun 23; Vol. 22 (13). Date of Electronic Publication: 2021 Jun 23.
Typ publikacji :
Journal Article
MeSH Terms :
Acetazolamide/*pharmacology
Antineoplastic Agents/*pharmacology
Calcium Channel Blockers/*pharmacology
Carbonic Anhydrase Inhibitors/*pharmacology
Cisplatin/*pharmacology
Fendiline/*pharmacology
Neuroblastoma/*drug therapy
Animals ; Apoptosis ; Cell Proliferation ; Drug Therapy, Combination ; Female ; Humans ; Male ; Mice ; Mice, Inbred NOD ; Mice, SCID ; Neuroblastoma/pathology ; Tumor Cells, Cultured ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
Cytoprotective Activity of p -Terphenyl Polyketides and Flavuside B from Marine-Derived Fungi against Oxidative Stress in Neuro-2a Cells.
Autorzy :
Yurchenko EA; Laboratory of Bioassays and Mechanism of Action of Biologically Active Substances, G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Prosp. 100 Let Vladivostoku 159, 690022 Vladivostok, Russia.
Menchinskaya ES; Laboratory of Bioassays and Mechanism of Action of Biologically Active Substances, G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Prosp. 100 Let Vladivostoku 159, 690022 Vladivostok, Russia.
Pislyagin EA; Laboratory of Bioassays and Mechanism of Action of Biologically Active Substances, G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Prosp. 100 Let Vladivostoku 159, 690022 Vladivostok, Russia.
Chingizova EA; Laboratory of Bioassays and Mechanism of Action of Biologically Active Substances, G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Prosp. 100 Let Vladivostoku 159, 690022 Vladivostok, Russia.
Girich EV; Laboratory of Chemistry of Microbial Metabolites, G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Prosp. 100 Let Vladivostoku 159, 690022 Vladivostok, Russia.
Yurchenko AN; Laboratory of Chemistry of Microbial Metabolites, G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Prosp. 100 Let Vladivostoku 159, 690022 Vladivostok, Russia.
Aminin DL; Laboratory of Bioassays and Mechanism of Action of Biologically Active Substances, G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Prosp. 100 Let Vladivostoku 159, 690022 Vladivostok, Russia.; Department of Biomedical Science and Environmental Biology, Kaohsiung Medical University, No.100, Shin-Chuan 1st Road, Sanmin Dist., Kaohsiung City 80708, Taiwan.
Mikhailov VV; Laboratory of Microbiology, G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Prosp. 100 Let Vladivostoku 159, 690022 Vladivostok, Russia.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Jun 13; Vol. 26 (12). Date of Electronic Publication: 2021 Jun 13.
Typ publikacji :
Journal Article
MeSH Terms :
Aspergillus/*chemistry
Cytoprotection/*drug effects
Glycosphingolipids/*pharmacology
Neuroblastoma/*drug therapy
Neuroprotective Agents/*pharmacology
Neurotoxins/*toxicity
Polyketides/*pharmacology
Animals ; Cell Line, Tumor ; Cell Survival ; Herbicides/toxicity ; Insecticides/toxicity ; Mice ; Neuroblastoma/metabolism ; Neuroblastoma/pathology ; Neuroprotective Agents/chemistry ; Paraquat/toxicity ; Polyketides/chemistry ; Reactive Oxygen Species ; Rotenone/toxicity
SCR Organism :
Aspergillus candidus
Czasopismo naukowe
Tytuł :
Age related gene DST represents an independent prognostic factor for MYCN non-amplified neuroblastoma.
Autorzy :
Wang H; Medical Research Center, Fujian Maternity and Child Health Hospital, Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China. .
Wang X; Medical Research Center, Fujian Maternity and Child Health Hospital, Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China.
Xu L; Medical Research Center, Fujian Maternity and Child Health Hospital, Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China.
Zhang J; State Key Laboratory for Medical Genomics, Shanghai Institute of Hematology, Rui-Jin Hospital Affiliated to School of Medicine, Shanghai Jiao Tong University, Shanghai, China. .
Cao H; Medical Research Center, Fujian Maternity and Child Health Hospital, Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China. .
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Źródło :
BMC pediatrics [BMC Pediatr] 2021 Jun 11; Vol. 21 (1), pp. 272. Date of Electronic Publication: 2021 Jun 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Amplification*
Neuroblastoma*/genetics
Child ; Dystonin ; Gene Expression ; Humans ; N-Myc Proto-Oncogene Protein/genetics ; N-Myc Proto-Oncogene Protein/metabolism ; Prognosis
Czasopismo naukowe
Tytuł :
Novel second-generation rexinoid induces growth arrest and reduces cancer cell stemness in human neuroblastoma patient-derived xenografts.
Autorzy :
Marayati R; Division of Pediatric Surgery, Department of Surgery, University of Alabama at Birmingham, 1600 7th Ave. South, Lowder Building, Suite 300, Birmingham, AL 35233, USA.
Bownes LV; Division of Pediatric Surgery, Department of Surgery, University of Alabama at Birmingham, 1600 7th Ave. South, Lowder Building, Suite 300, Birmingham, AL 35233, USA.
Quinn CH; Division of Pediatric Surgery, Department of Surgery, University of Alabama at Birmingham, 1600 7th Ave. South, Lowder Building, Suite 300, Birmingham, AL 35233, USA.
Wadhwani N; Division of Pediatric Surgery, Department of Surgery, University of Alabama at Birmingham, 1600 7th Ave. South, Lowder Building, Suite 300, Birmingham, AL 35233, USA.
Williams AP; Division of Pediatric Surgery, Department of Surgery, University of Alabama at Birmingham, 1600 7th Ave. South, Lowder Building, Suite 300, Birmingham, AL 35233, USA.
Markert HR; Division of Pediatric Surgery, Department of Surgery, University of Alabama at Birmingham, 1600 7th Ave. South, Lowder Building, Suite 300, Birmingham, AL 35233, USA.
Atigadda V; Department of Dermatology, University of Alabama at Birmingham, Birmingham, AL 35233, USA.
Aye JM; Division of Pediatric Hematology Oncology, Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL 35233, USA.
Stewart JE; Division of Pediatric Surgery, Department of Surgery, University of Alabama at Birmingham, 1600 7th Ave. South, Lowder Building, Suite 300, Birmingham, AL 35233, USA.
Yoon KJ; Department of Pharmacology and Toxicology, University of Alabama at Birmingham, Birmingham, AL 35233, USA.
Beierle EA; Division of Pediatric Surgery, Department of Surgery, University of Alabama at Birmingham, 1600 7th Ave. South, Lowder Building, Suite 300, Birmingham, AL 35233, USA. Electronic address: .
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Źródło :
Journal of pediatric surgery [J Pediatr Surg] 2021 Jun; Vol. 56 (6), pp. 1165-1173. Date of Electronic Publication: 2021 Feb 24.
Typ publikacji :
Journal Article
MeSH Terms :
Neoplasm Recurrence, Local*
Neuroblastoma*/drug therapy
Cell Differentiation ; Cell Line, Tumor ; Cell Proliferation ; Child ; Heterografts ; Humans ; Neoplastic Stem Cells
Czasopismo naukowe
Tytuł :
Myeloablative Busulfan/Melphalan Consolidation following Induction Chemotherapy for Patients with Newly Diagnosed High-Risk Neuroblastoma: Children's Oncology Group Trial ANBL12P1.
Autorzy :
Granger MM; Department of Pediatrics, Cook Children's Medical Center, Fort Worth, Texas. Electronic address: .
Naranjo A; Children's Oncology Group Statistics & Data Center, Department of Biostatistics, University of Florida, Gainesville, Florida.
Bagatell R; Department of Pediatrics, Children's Hospital of Philadelphia and Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
DuBois SG; Dana-Farber / Boston Children's Cancer and Blood Disorder Center and Harvard Medical School, Boston, Massachusetts.
McCune JS; Department of Population Sciences, City of Hope, Duarte, California.
Tenney SC; Children's Oncology Group Statistics & Data Center, Department of Biostatistics, University of Florida, Gainesville, Florida.
Weiss BD; Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Mosse YP; Department of Pediatrics, Children's Hospital of Philadelphia and Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Asgharzadeh S; Department of Pediatrics, Children's Hospital of Los Angeles, Los Angeles, California.
Grupp SA; Department of Pediatrics, Children's Hospital of Philadelphia and Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Hogarty MD; Department of Pediatrics, Children's Hospital of Philadelphia and Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Gastier-Foster JM; Institute for Genomic Medicine, Nationwide Children's Hospital and Departments of Pathology and Pediatrics, Ohio State University College of Medicine, Columbus, Ohio.
Mills D; Department of Nursing, Hospital for Sick Children, Toronto, Ontario, Canada.
Shulkin BL; Department of Radiological Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee.
Parisi MT; Departments of Radiology, Seattle Children's Hospital/University of Washington School of Medicine, Seattle, Washington.
London WB; Dana-Farber / Boston Children's Cancer and Blood Disorder Center and Harvard Medical School, Boston, Massachusetts.
Han-Chang J; Department of Radiation Oncology, University of Oklahoma Health Science Center, Oklahoma City, Oklahoma.
Panoff J; Department of Radiation Oncology, Miami Cancer Institute, Baptist Health South Florida.
von Allmen D; Department of Surgery, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Jarzembowski JA; Department of Pathology, Midwest Children's Cancer Center, Milwaukee, Wisconsin.
Park JR; Departments of Pediatrics, Seattle Children's Hospital/University of Washington School of Medicine, Seattle, Washington.
Yanik GA; Department of Pediatrics, University of Michigan Medical Center, Ann Arbor, Michigan.
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Źródło :
Transplantation and cellular therapy [Transplant Cell Ther] 2021 Jun; Vol. 27 (6), pp. 490.e1-490.e8. Date of Electronic Publication: 2021 Mar 06.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Hematopoietic Stem Cell Transplantation*
Neuroblastoma*/drug therapy
Busulfan/adverse effects ; Child ; Humans ; Induction Chemotherapy ; Melphalan/adverse effects ; Transplantation, Autologous
Czasopismo naukowe
Tytuł :
Effects of antiepileptic drugs' administration during pregnancy on the nerve cell proliferation and axonal outgrowth of human neuroblastoma SH-SY5Y nerve cells.
Autorzy :
Kakumoto M; Laboratory of Clinical Pharmacy, College of Pharmaceutical Sciences, Ritsumeikan University, Noji-higashi 1-1-1, Kusatsu, Shiga, 525-8577, Japan. Electronic address: .
Shimokawa K; Laboratory of Clinical Pharmacy, College of Pharmaceutical Sciences, Ritsumeikan University, Noji-higashi 1-1-1, Kusatsu, Shiga, 525-8577, Japan.
Ueshima S; Laboratory of Clinical Pharmacy, College of Pharmaceutical Sciences, Ritsumeikan University, Noji-higashi 1-1-1, Kusatsu, Shiga, 525-8577, Japan.
Hira D; Laboratory of Clinical Pharmacy, College of Pharmaceutical Sciences, Ritsumeikan University, Noji-higashi 1-1-1, Kusatsu, Shiga, 525-8577, Japan.
Okano T; Laboratory of Clinical Pharmacy, College of Pharmaceutical Sciences, Ritsumeikan University, Noji-higashi 1-1-1, Kusatsu, Shiga, 525-8577, Japan.
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2021 May 21; Vol. 554, pp. 151-157. Date of Electronic Publication: 2021 Mar 30.
Typ publikacji :
Journal Article
MeSH Terms :
Anticonvulsants/*pharmacology
Epilepsy/*drug therapy
NAV1.1 Voltage-Gated Sodium Channel/*metabolism
Neuroblastoma/*drug therapy
Neuronal Outgrowth/*drug effects
Neurons/*drug effects
Prenatal Exposure Delayed Effects/*drug therapy
Carbamazepine/pharmacology ; Cell Line, Tumor ; Cell Proliferation ; Child ; Epilepsy/complications ; Epilepsy/metabolism ; Female ; Humans ; Lamotrigine/pharmacology ; NAV1.1 Voltage-Gated Sodium Channel/genetics ; Neuroblastoma/complications ; Neuroblastoma/metabolism ; Phenytoin/pharmacology ; Pregnancy ; Valproic Acid/pharmacology
Czasopismo naukowe
Tytuł :
miRNA-34a-5p regulates progression of neuroblastoma via modulating the Wnt/β-catenin signaling pathway by targeting SOX4.
Autorzy :
Wang Y; Qingdao Municipal Hospital Affiliated to Qingdao University.
Guan E; Qingdao Municipal Hospital Affiliated to Qingdao University.
Li D; Qingdao Women and Children's Hospital.
Sun L; The Affiliated Hospital of Qingdao University, No. 16 Jiangsu Road, Qingdao, P.R. China.
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Źródło :
Medicine [Medicine (Baltimore)] 2021 May 21; Vol. 100 (20), pp. e25827.
Typ publikacji :
Journal Article; Observational Study
MeSH Terms :
Gene Expression Regulation, Neoplastic*
MicroRNAs/*metabolism
Neuroblastoma/*genetics
SOXC Transcription Factors/*genetics
Wnt Signaling Pathway/*genetics
Apoptosis/genetics ; Cell Line, Tumor ; Cell Movement/genetics ; Cell Proliferation ; Child ; Disease Progression ; Female ; Humans ; Male ; Neoplasm Invasiveness/genetics ; Neuroblastoma/pathology ; Neuroblastoma/surgery ; SOXC Transcription Factors/metabolism ; beta Catenin/metabolism
Czasopismo naukowe
Tytuł :
Cannabidiol regulates CB1-pSTAT3 signaling for neurite outgrowth, prolongs lifespan, and improves health span in Caenorhabditis elegans of Aβ pathology models.
Autorzy :
Wang Z; Australian Centre for Cannabinoid Clinical and Research Excellence (ACRE), New Lambton Heights, NSW, Australia.; Illawarra Health and Medical Research Institute (IHMRI) and School of Medicine, University of Wollongong, Wollongong, NSW, Australia.
Zheng P; Illawarra Health and Medical Research Institute (IHMRI) and School of Medicine, University of Wollongong, Wollongong, NSW, Australia.
Xie Y; Illawarra Health and Medical Research Institute (IHMRI) and School of Medicine, University of Wollongong, Wollongong, NSW, Australia.
Chen X; Illawarra Health and Medical Research Institute (IHMRI) and School of Medicine, University of Wollongong, Wollongong, NSW, Australia.
Solowij N; Australian Centre for Cannabinoid Clinical and Research Excellence (ACRE), New Lambton Heights, NSW, Australia.; Illawarra Health and Medical Research Institute (IHMRI) and School of Medicine, University of Wollongong, Wollongong, NSW, Australia.; School of Psychology, University of Wollongong, Wollongong, NSW, Australia.
Green K; Australian Centre for Cannabinoid Clinical and Research Excellence (ACRE), New Lambton Heights, NSW, Australia.; Illawarra Health and Medical Research Institute (IHMRI) and School of Medicine, University of Wollongong, Wollongong, NSW, Australia.; Molecular Horizons, School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW, Australia.
Chew YL; Illawarra Health and Medical Research Institute (IHMRI) and School of Medicine, University of Wollongong, Wollongong, NSW, Australia.; Molecular Horizons, School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW, Australia.
Huang XF; Australian Centre for Cannabinoid Clinical and Research Excellence (ACRE), New Lambton Heights, NSW, Australia.; Illawarra Health and Medical Research Institute (IHMRI) and School of Medicine, University of Wollongong, Wollongong, NSW, Australia.; Molecular Horizons, School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW, Australia.
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Źródło :
FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2021 May; Vol. 35 (5), pp. e21537.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Longevity*
Neuronal Outgrowth*
Amyloid beta-Peptides/*toxicity
Caenorhabditis elegans/*growth & development
Cannabidiol/*pharmacology
Neuroblastoma/*drug therapy
Receptor, Cannabinoid, CB1/*metabolism
STAT3 Transcription Factor/*metabolism
Animals ; Animals, Genetically Modified/genetics ; Animals, Genetically Modified/growth & development ; Anticonvulsants/pharmacology ; Caenorhabditis elegans/drug effects ; Caenorhabditis elegans/genetics ; Disease Models, Animal ; Mice ; Mice, Inbred C57BL ; Neuroblastoma/metabolism ; Neuroblastoma/pathology ; Neurons/cytology ; Neurons/metabolism ; Neuroprotective Agents ; Phosphorylation ; Receptor, Cannabinoid, CB1/genetics ; STAT3 Transcription Factor/genetics
Czasopismo naukowe
Tytuł :
ZIF-8 nano confined protein-titanocene complex core-shell MOFs for efficient therapy of Neuroblastoma: Optimization, molecular dynamics and toxicity studies.
Autorzy :
Kulkarni S; Department of Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal 576104, Karnataka State, India.
Pandey A; Department of Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal 576104, Karnataka State, India.
Nikam AN; Department of Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal 576104, Karnataka State, India.
Nannuri SH; Department of Atomic and Molecular Physics, Manipal Academy of Higher Education, Manipal 576104, Karnataka State, India.
George SD; Department of Atomic and Molecular Physics, Manipal Academy of Higher Education, Manipal 576104, Karnataka State, India.
Fayaz SMA; Department of Biotechnology, Manipal Institute of Technology, Manipal Academy of Higher Education, Manipal 576104, Karnataka State, India.
Vincent AP; Department of Research and Development, Glanbia Nutritionals, Twin Falls, ID, USA.
Mutalik S; Department of Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal 576104, Karnataka State, India. Electronic address: .
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Źródło :
International journal of biological macromolecules [Int J Biol Macromol] 2021 May 01; Vol. 178, pp. 444-463. Date of Electronic Publication: 2021 Feb 24.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents*/adverse effects
Antineoplastic Agents*/chemistry
Antineoplastic Agents*/pharmacology
Fluorouracil*/adverse effects
Fluorouracil*/chemistry
Fluorouracil*/pharmacology
Imidazoles*/adverse effects
Imidazoles*/chemistry
Imidazoles*/pharmacology
Metal-Organic Frameworks*/adverse effects
Metal-Organic Frameworks*/chemistry
Metal-Organic Frameworks*/pharmacology
Molecular Dynamics Simulation*
Nanoparticles*/adverse effects
Nanoparticles*/chemistry
Nanoparticles*/therapeutic use
Neuroblastoma*/drug therapy
Neuroblastoma*/metabolism
Organometallic Compounds*/adverse effects
Organometallic Compounds*/chemistry
Organometallic Compounds*/pharmacology
Animals ; Rats ; Rats, Wistar
Czasopismo naukowe

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