- Tytuł :
- Hypericum perforatum extract and hyperforin inhibit the growth of neurotropic parasite Toxoplasma gondii and infection-induced inflammatory responses of glial cells in vitro.
- Autorzy :
- Źródło :
- Journal of ethnopharmacology [J Ethnopharmacol] 2021 Mar 01; Vol. 267, pp. 113525. Date of Electronic Publication: 2020 Oct 28.
- Typ publikacji :
- Journal Article
- MeSH Terms :
-
Hypericum*/chemistry
Coccidiostats/*pharmacologyNeuroglia /*drug effects
Neuroprotective Agents/*pharmacology
Phloroglucinol/*analogs & derivatives
Plant Extracts/*pharmacology
Terpenes/*pharmacology
Toxoplasma/*drug effects
Toxoplasmosis, Cerebral/*drug therapy
Animals ; Chlorocebus aethiops ; Coccidiostats/isolation & purification ; Cytokines ; Inflammation Mediators/metabolism ; Mice ; Mice, Inbred C57BL ;Neuroglia /metabolism ;Neuroglia /parasitology ;Neuroglia /pathology ; Neuroprotective Agents/isolation & purification ; Phloroglucinol/isolation & purification ; Phloroglucinol/pharmacology ; Plant Extracts/isolation & purification ; RAW 264.7 Cells ; Terpenes/isolation & purification ; Toxoplasma/growth & development ; Toxoplasmosis, Cerebral/metabolism ; Toxoplasmosis, Cerebral/parasitology ; Toxoplasmosis, Cerebral/pathology ; Vero Cells -
Czasopismo naukowe