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Wyszukujesz frazę ""NEUROPROTECTIVE agents"" wg kryterium: Temat


Tytuł :
The neuroprotective effects of polyphenols, their role in innate immunity and the interplay with the microbiota.
Autorzy :
Annunziata G; NutraPharmaLabs, Department of Pharmacy, University of Naples Federico II, Via Domenico Montesano 49, 80131, Naples, Italy. Electronic address: .
Sureda A; Research Group in Community Nutrition and Oxidative Stress and Health Research Institute of the Balearic Islands (IdISBa), University of Balearic Islands-IUNICS, E-07122, Palma de Mallorca, Spain; CIBEROBN (Physiopathology of Obesity and Nutrition), Istituto de Salud Carlos III, 28029 Madrid, Spain. Electronic address: .
Orhan IE; Department of Pharmacognosy, Faculty of Pharmacy, Gazi University, 06330, Ankara, Turkey. Electronic address: .
Battino M; Nutrition and Food Science Group, Department of Analytical and Food Chemistry, CITACA, CACTI, University of Vigo - Vigo Campus, Vigo, Spain; Dept of Clinical Sciences, Università Politecnica delle Marche, Ancona, Italy; International Research Center for Food Nutrition and Safety, Jiangsu University, Zhenjiang, 212013, China. Electronic address: .
Arnone A; Dipartimento di Medicina Clinica e Chirurgia, Unit of Endocrinology, Federico II University Medical School of Naples, Via Sergio Pansini 5, 80131, Naples, Italy. Electronic address: .
Jiménez-García M; Laboratory of Neurophysiology, Biology Department, University of Balearic Islands (UIB), Ctra. Valldemossa Km 7.5, E-07122, Palma de Mallorca, Spain. Electronic address: .
Capó X; Research Group in Community Nutrition and Oxidative Stress and Health Research Institute of the Balearic Islands (IdISBa), University of Balearic Islands-IUNICS, E-07122, Palma de Mallorca, Spain. Electronic address: .
Cabot J; Biology Department, University of Balearic Islands (UIB), Ctra. Valldemossa Km 7.5, E-07122 Palma de Mallorca, Spain. Electronic address: .
Sanadgol N; Department of Biology, Faculty of Sciences, University of Zabol, Zabol, Iran; Department of Biomolecular Sciences, School of Pharmaceutical Sciences of Ribeirao Preto, University of Sao Paulo, Ribeirao Preto, Brazil. Electronic address: .
Giampieri F; Department of Odontostomatologic and Specialized Clinical Sciences, Faculty of Medicine, Polytechnic University of Marche, Ancona, Italy; Department of Biochemistry, Faculty of Sciences, King Abdulaziz University, Jeddah, Saudi Arabia. Electronic address: .
Tenore GC; NutraPharmaLabs, Department of Pharmacy, University of Naples Federico II, Via Domenico Montesano 49, 80131, Naples, Italy. Electronic address: .
Kashani HRK; Imam Hossein Hospital, Madani street, Theran, Iran. Electronic address: .
Silva AS; National Institute of Agrarian and Veterinary Research (INIAV), Rua dos Lágidos, Lugar da Madalena, Vairão, Vila do Conde, Oporto, 4485-655, Portugal; Center for Study in Animal Science (CECA), ICETA, University of Oporto, Oporto, Portugal. Electronic address: .
Habtemariam S; Pharmacognosy Research Laboratories & Herbal Analysis Services UK, University of Greenwich, Central Avenue, Charham-Maritime, Kent, ME4 4TB, UK. Electronic address: .
Nabavi SF; Applied Biotechnology Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran. Electronic address: .
Nabavi SM; Applied Biotechnology Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran. Electronic address: .
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Źródło :
Neuroscience and biobehavioral reviews [Neurosci Biobehav Rev] 2021 Sep; Vol. 128, pp. 437-453. Date of Electronic Publication: 2021 Jul 07.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Gastrointestinal Microbiome*
Microbiota*
Neuroprotective Agents*/pharmacology
Neuroprotective Agents*/therapeutic use
Aged ; Humans ; Immunity, Innate ; Polyphenols/pharmacology
Czasopismo naukowe
Tytuł :
Characterization, antioxidant, and neuroprotective effects of anthocyanins from Nitraria tangutorum Bobr. fruit.
Autorzy :
Chen S; CAS Key Laboratory of Tibetan Medicine Research, Northwest Institute of Plateau Biology, Xining 810008, PR China.
Zhou H; CAS Key Laboratory of Tibetan Medicine Research, Northwest Institute of Plateau Biology, Xining 810008, PR China.
Zhang G; CAS Key Laboratory of Tibetan Medicine Research, Northwest Institute of Plateau Biology, Xining 810008, PR China.
Dong Q; CAS Key Laboratory of Tibetan Medicine Research, Northwest Institute of Plateau Biology, Xining 810008, PR China; Qinghai Provincial Key Laboratory of Tibetan Medicine Research, Xining 810001, PR China.
Wang Z; CAS Key Laboratory of Tibetan Medicine Research, Northwest Institute of Plateau Biology, Xining 810008, PR China.
Wang H; CAS Key Laboratory of Tibetan Medicine Research, Northwest Institute of Plateau Biology, Xining 810008, PR China; Huzhou Plateau Biological Resource Centre of Innovation, Northwest Institute of Plateau Biology, Chinese Academy of Sciences, Huzhou 313000, PR China; Qinghai Provincial Key Laboratory of Tibetan Medicine Research, Xining 810001, PR China.
Hu N; CAS Key Laboratory of Tibetan Medicine Research, Northwest Institute of Plateau Biology, Xining 810008, PR China; Huzhou Plateau Biological Resource Centre of Innovation, Northwest Institute of Plateau Biology, Chinese Academy of Sciences, Huzhou 313000, PR China; Qinghai Provincial Key Laboratory of Tibetan Medicine Research, Xining 810001, PR China. Electronic address: .
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Źródło :
Food chemistry [Food Chem] 2021 Aug 15; Vol. 353, pp. 129435. Date of Electronic Publication: 2021 Mar 03.
Typ publikacji :
Journal Article
MeSH Terms :
Chromatography, High Pressure Liquid*
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization*
Anthocyanins/*analysis
Antioxidants/*chemistry
Magnoliopsida/*chemistry
Neuroprotective Agents/*analysis
Amyloid beta-Peptides/genetics ; Amyloid beta-Peptides/metabolism ; Animals ; Anthocyanins/chemistry ; Anthocyanins/isolation & purification ; Anthocyanins/pharmacology ; Female ; Fruit/chemistry ; Fruit/metabolism ; Hippocampus/drug effects ; Hippocampus/metabolism ; Magnoliopsida/metabolism ; Malondialdehyde/metabolism ; Neuroprotective Agents/chemistry ; Neuroprotective Agents/isolation & purification ; Neuroprotective Agents/pharmacology ; Peptide Fragments/genetics ; Peptide Fragments/metabolism ; Plant Extracts/chemistry ; Rats ; Rats, Sprague-Dawley ; Reactive Oxygen Species/metabolism ; Receptor for Advanced Glycation End Products/genetics ; Receptor for Advanced Glycation End Products/metabolism ; Superoxide Dismutase/metabolism
Czasopismo naukowe
Tytuł :
Overview of piperlongumine analogues and their therapeutic potential.
Autorzy :
Zhu P; Medical School, Nantong University, Nantong, 226001, China; School of Pharmacy and Jiangsu Province Key Laboratory for Inflammation and Molecular Drug Target, Nantong University, Nantong, 226001, China; State Key Laboratory of Quality Research in Chinese Medicines, Macau Institute for Applied Research in Medicine and Health, Macau University of Science and Technology, Macau.
Qian J; Medical School, Nantong University, Nantong, 226001, China; School of Pharmacy and Jiangsu Province Key Laboratory for Inflammation and Molecular Drug Target, Nantong University, Nantong, 226001, China.
Xu Z; Medical School, Nantong University, Nantong, 226001, China; School of Pharmacy and Jiangsu Province Key Laboratory for Inflammation and Molecular Drug Target, Nantong University, Nantong, 226001, China.
Meng C; School of Pharmacy and Jiangsu Province Key Laboratory for Inflammation and Molecular Drug Target, Nantong University, Nantong, 226001, China.
Zhu W; Medical School, Nantong University, Nantong, 226001, China; School of Pharmacy and Jiangsu Province Key Laboratory for Inflammation and Molecular Drug Target, Nantong University, Nantong, 226001, China.
Ran F; School of Pharmacy and Jiangsu Province Key Laboratory for Inflammation and Molecular Drug Target, Nantong University, Nantong, 226001, China.
Zhang W; State Key Laboratory of Quality Research in Chinese Medicines, Macau Institute for Applied Research in Medicine and Health, Macau University of Science and Technology, Macau. Electronic address: .
Zhang Y; Medical School, Nantong University, Nantong, 226001, China; School of Pharmacy and Jiangsu Province Key Laboratory for Inflammation and Molecular Drug Target, Nantong University, Nantong, 226001, China. Electronic address: .
Ling Y; Medical School, Nantong University, Nantong, 226001, China; School of Pharmacy and Jiangsu Province Key Laboratory for Inflammation and Molecular Drug Target, Nantong University, Nantong, 226001, China. Electronic address: .
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Źródło :
European journal of medicinal chemistry [Eur J Med Chem] 2021 Aug 05; Vol. 220, pp. 113471. Date of Electronic Publication: 2021 Apr 21.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Anti-Inflammatory Agents, Non-Steroidal/*pharmacology
Antineoplastic Agents, Phytogenic/*pharmacology
Dioxolanes/*pharmacology
Hypoglycemic Agents/*pharmacology
Neuroprotective Agents/*pharmacology
Platelet Aggregation Inhibitors/*pharmacology
Anti-Inflammatory Agents, Non-Steroidal/chemistry ; Anti-Inflammatory Agents, Non-Steroidal/isolation & purification ; Antineoplastic Agents, Phytogenic/chemistry ; Antineoplastic Agents, Phytogenic/isolation & purification ; Dioxolanes/chemistry ; Dioxolanes/isolation & purification ; Humans ; Hypoglycemic Agents/chemistry ; Hypoglycemic Agents/isolation & purification ; Molecular Structure ; Neuroprotective Agents/chemistry ; Neuroprotective Agents/isolation & purification ; Piper/chemistry ; Platelet Aggregation Inhibitors/chemistry ; Platelet Aggregation Inhibitors/isolation & purification
Czasopismo naukowe
Tytuł :
Mechanistic insights and perspectives involved in neuroprotective action of quercetin.
Autorzy :
Grewal AK; Chitkara College of Pharmacy, Chitkara University, Punjab, India. Electronic address: .
Singh TG; Chitkara College of Pharmacy, Chitkara University, Punjab, India. Electronic address: .
Sharma D; Chitkara College of Pharmacy, Chitkara University, Punjab, India. Electronic address: .
Sharma V; Chitkara College of Pharmacy, Chitkara University, Punjab, India. Electronic address: .
Singh M; Chitkara College of Pharmacy, Chitkara University, Punjab, India. Electronic address: .
Rahman MH; Department of Pharmacy, Southeast University, Banani, Dhaka 1213, Bangladesh. Electronic address: .
Najda A; Laboratory of Quality of Vegetables and Medicinal Plants, Department of Vegetable Crops and Medicinal Plants, University of Life Sciences in Lublin, 15 Akademicka Street, 20-950 Lublin, Poland. Electronic address: .
Walasek-Janusz M; Laboratory of Quality of Vegetables and Medicinal Plants, Department of Vegetable Crops and Medicinal Plants, University of Life Sciences in Lublin, 15 Akademicka Street, 20-950 Lublin, Poland. Electronic address: .
Kamel M; Department of Medicine and Infectious Diseases, Faculty of Veterinary Medicine, Cairo University, 12211 Giza, Egypt. Electronic address: .
Albadrani GM; Department of Biology, College of Science, Princess Nourah bint Abdulrahman University, Riyadh 11474, Saudi Arabia. Electronic address: .
Akhtar MF; Riphah Institute of Pharmaceutical Sciences, Riphah International University, Lahore Campus, Pakistan. Electronic address: .
Saleem A; Department of Pharmacology, Faculty of Pharmaceutical Sciences, Government College University Faisalabad, Faisalabad, Pakistan. Electronic address: .
Abdel-Daim MM; Pharmacology Department, Faculty of Veterinary Medicine, Suez Canal University, Ismailia 41522, Egypt. Electronic address: .
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Źródło :
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2021 Aug; Vol. 140, pp. 111729. Date of Electronic Publication: 2021 May 25.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Neurodegenerative Diseases/*drug therapy
Neuroprotective Agents/*therapeutic use
Quercetin/*therapeutic use
Animals ; Humans ; Neurodegenerative Diseases/etiology ; Neuroprotection ; Neuroprotective Agents/chemistry ; Neuroprotective Agents/pharmacokinetics ; Neuroprotective Agents/pharmacology ; Quercetin/chemistry ; Quercetin/pharmacokinetics ; Quercetin/pharmacology ; Signal Transduction/drug effects
Czasopismo naukowe
Tytuł :
Bidentatide, a Novel Plant Peptide Derived from Achyranthes bidentata Blume: Isolation, Characterization, and Neuroprotection through Inhibition of NR2B-Containing NMDA Receptors.
Autorzy :
Ding F; Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education, Co-Innovation Center of Neuroregeneration, Nantong University, 19 Qixiu Road, Nantong 226001, China.
Bai Y; CAS Key Laboratory of Separation Sciences of Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Zhongshan Road 457, Dalian 116023, China.
Cheng Q; Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education, Co-Innovation Center of Neuroregeneration, Nantong University, 19 Qixiu Road, Nantong 226001, China.
Yu S; Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education, Co-Innovation Center of Neuroregeneration, Nantong University, 19 Qixiu Road, Nantong 226001, China.
Cheng M; CAS Key Laboratory of Separation Sciences of Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Zhongshan Road 457, Dalian 116023, China.
Wu Y; CAS Key Laboratory of Separation Sciences of Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Zhongshan Road 457, Dalian 116023, China.; School of Pharmacy, Henan University of Chinese Medicine, East Jinshui Road 156, Zhengzhou 450046, China.
Zhang X; CAS Key Laboratory of Separation Sciences of Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Zhongshan Road 457, Dalian 116023, China.; Partner Group of Max Planck Society, Dalian 116023, China.
Liang X; CAS Key Laboratory of Separation Sciences of Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Zhongshan Road 457, Dalian 116023, China.
Gu X; Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education, Co-Innovation Center of Neuroregeneration, Nantong University, 19 Qixiu Road, Nantong 226001, China.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jul 26; Vol. 22 (15). Date of Electronic Publication: 2021 Jul 26.
Typ publikacji :
Journal Article
MeSH Terms :
Neuroprotective Agents*/chemistry
Neuroprotective Agents*/isolation & purification
Neuroprotective Agents*/pharmacology
Peptides*/chemistry
Peptides*/isolation & purification
Peptides*/pharmacology
Plant Proteins*/chemistry
Plant Proteins*/isolation & purification
Plant Proteins*/pharmacology
Achyranthes/*chemistry
Hippocampus/*metabolism
Neurons/*metabolism
Receptors, N-Methyl-D-Aspartate/*antagonists & inhibitors
Animals ; Apoptosis/drug effects ; Calcium/metabolism ; Rats ; Rats, Sprague-Dawley ; Receptors, N-Methyl-D-Aspartate/metabolism
Czasopismo naukowe
Tytuł :
Synthesis and Biological Assessment of 4,1-Benzothiazepines with Neuroprotective Activity on the Ca Overload for the Treatment of Neurodegenerative Diseases and Stroke.
Autorzy :
Viejo L; Instituto-Fundación Teófilo Hernando and Departamento de Farmacología y Terapéutica, Universidad Autónoma de Madrid, C/Arzobispo Morcillo, 4, 28029 Madrid, Spain.; Instituto de Investigación Sanitaria, Servicio de Farmacología Clínica, Hospital Universitario de La Princesa, 28006 Madrid, Spain.
Rubio-Alarcón M; Instituto-Fundación Teófilo Hernando and Departamento de Farmacología y Terapéutica, Universidad Autónoma de Madrid, C/Arzobispo Morcillo, 4, 28029 Madrid, Spain.
Arribas RL; Instituto-Fundación Teófilo Hernando and Departamento de Farmacología y Terapéutica, Universidad Autónoma de Madrid, C/Arzobispo Morcillo, 4, 28029 Madrid, Spain.
Moreno-Castro M; Instituto-Fundación Teófilo Hernando and Departamento de Farmacología y Terapéutica, Universidad Autónoma de Madrid, C/Arzobispo Morcillo, 4, 28029 Madrid, Spain.
Pérez-Marín R; Instituto-Fundación Teófilo Hernando and Departamento de Farmacología y Terapéutica, Universidad Autónoma de Madrid, C/Arzobispo Morcillo, 4, 28029 Madrid, Spain.
Braun-Cornejo M; Instituto-Fundación Teófilo Hernando and Departamento de Farmacología y Terapéutica, Universidad Autónoma de Madrid, C/Arzobispo Morcillo, 4, 28029 Madrid, Spain.
Estrada-Valencia M; Instituto-Fundación Teófilo Hernando and Departamento de Farmacología y Terapéutica, Universidad Autónoma de Madrid, C/Arzobispo Morcillo, 4, 28029 Madrid, Spain.
de Los Ríos C; Instituto-Fundación Teófilo Hernando and Departamento de Farmacología y Terapéutica, Universidad Autónoma de Madrid, C/Arzobispo Morcillo, 4, 28029 Madrid, Spain.; Instituto de Investigación Sanitaria, Servicio de Farmacología Clínica, Hospital Universitario de La Princesa, 28006 Madrid, Spain.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Jul 24; Vol. 26 (15). Date of Electronic Publication: 2021 Jul 24.
Typ publikacji :
Journal Article
MeSH Terms :
Neuroprotective Agents*/chemical synthesis
Neuroprotective Agents*/pharmacology
Thiazepines*/chemical synthesis
Thiazepines*/pharmacology
Neurodegenerative Diseases/*drug therapy
Neurons/*drug effects
Neuroprotection/*drug effects
Stroke/*drug therapy
Animals ; Calcium/metabolism ; Calcium Channel Blockers/chemical synthesis ; Calcium Channel Blockers/pharmacology ; Calcium Signaling/drug effects ; Cell Line, Tumor ; Female ; Humans ; Mitochondria ; Neurons/pathology ; Rats
Czasopismo naukowe
Tytuł :
Selective Pseudo-irreversible Butyrylcholinesterase Inhibitors Transferring Antioxidant Moieties to the Enzyme Show Pronounced Neuroprotective Efficacy In Vitro and In Vivo in an Alzheimer's Disease Mouse Model.
Autorzy :
Scheiner M; Pharmaceutical and Medicinal Chemistry, Institute of Pharmacy and Food Chemistry, Julius Maximilian University of Würzburg, Am Hubland, 97074 Würzburg, Germany.
Hoffmann M; Pharmaceutical and Medicinal Chemistry, Institute of Pharmacy and Food Chemistry, Julius Maximilian University of Würzburg, Am Hubland, 97074 Würzburg, Germany.
He F; Pharmaceutical and Medicinal Chemistry, Institute of Pharmacy and Food Chemistry, Julius Maximilian University of Würzburg, Am Hubland, 97074 Würzburg, Germany.
Poeta E; Department of Pharmacy and Biotechnology, University of Bologna, Via Selmi 3, 40126 Bologna, Italy.
Chatonnet A; DMEM, University of Montpellier, INRAE, 34060 Montpellier, France.
Monti B; Department of Pharmacy and Biotechnology, University of Bologna, Via Selmi 3, 40126 Bologna, Italy.
Maurice T; MMDN, University of Montpellier, INSERM, EPHE, 34095 Montpellier, France.
Decker M; Pharmaceutical and Medicinal Chemistry, Institute of Pharmacy and Food Chemistry, Julius Maximilian University of Würzburg, Am Hubland, 97074 Würzburg, Germany.
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Źródło :
Journal of medicinal chemistry [J Med Chem] 2021 Jul 08; Vol. 64 (13), pp. 9302-9320. Date of Electronic Publication: 2021 Jun 21.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Disease Models, Animal*
Alzheimer Disease/*drug therapy
Antioxidants/*pharmacology
Cholinesterase Inhibitors/*pharmacology
Neuroprotective Agents/*pharmacology
Acetylcholinesterase/metabolism ; Alzheimer Disease/metabolism ; Animals ; Antioxidants/chemical synthesis ; Antioxidants/chemistry ; Biphenyl Compounds/antagonists & inhibitors ; Butyrylcholinesterase/deficiency ; Butyrylcholinesterase/metabolism ; Cell Survival/drug effects ; Cells, Cultured ; Cholinesterase Inhibitors/chemical synthesis ; Cholinesterase Inhibitors/chemistry ; Chromans/chemical synthesis ; Chromans/chemistry ; Chromans/pharmacology ; Cinnamates/chemical synthesis ; Cinnamates/chemistry ; Cinnamates/pharmacology ; Dose-Response Relationship, Drug ; Humans ; Male ; Melatonin/chemical synthesis ; Melatonin/chemistry ; Melatonin/pharmacology ; Mice ; Molecular Structure ; Neuroprotective Agents/chemical synthesis ; Neuroprotective Agents/chemistry ; Picrates/antagonists & inhibitors ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Multifunctional Selenium Quantum Dots for the Treatment of Alzheimer's Disease by Reducing Aβ-Neurotoxicity and Oxidative Stress and Alleviate Neuroinflammation.
Autorzy :
Guo X; College of Chemistry and Materials Science, Jinan University, Guangzhou 510632, China.
Lie Q; College of Chemistry and Materials Science, Jinan University, Guangzhou 510632, China.
Liu Y; College of Chemistry and Materials Science, Jinan University, Guangzhou 510632, China.; College of Life Sciences and Oceanography, Shenzhen University, Shenzhen 518060, China.
Jia Z; College of Chemistry and Materials Science, Jinan University, Guangzhou 510632, China.
Gong Y; College of Chemistry and Materials Science, Jinan University, Guangzhou 510632, China.
Yuan X; College of Chemistry and Materials Science, Jinan University, Guangzhou 510632, China.
Liu J; College of Chemistry and Materials Science, Jinan University, Guangzhou 510632, China.
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Źródło :
ACS applied materials & interfaces [ACS Appl Mater Interfaces] 2021 Jul 07; Vol. 13 (26), pp. 30261-30273. Date of Electronic Publication: 2021 Jun 25.
Typ publikacji :
Journal Article
MeSH Terms :
Alzheimer Disease/*drug therapy
Free Radical Scavengers/*therapeutic use
Inflammation/*drug therapy
Neuroprotective Agents/*therapeutic use
Oxidative Stress/*drug effects
Quantum Dots/*therapeutic use
Alzheimer Disease/complications ; Alzheimer Disease/metabolism ; Amyloid beta-Peptides/metabolism ; Animals ; Blood-Brain Barrier/physiology ; Cell Line, Tumor ; Free Radical Scavengers/chemistry ; Free Radical Scavengers/metabolism ; Humans ; Inflammation/etiology ; Male ; Memory/drug effects ; Mice ; Neuroprotective Agents/chemistry ; Neuroprotective Agents/metabolism ; Open Field Test/drug effects ; Particle Size ; Phosphorylation/drug effects ; Protein Multimerization/drug effects ; Quantum Dots/chemistry ; Quantum Dots/metabolism ; Selenium/chemistry ; Selenium/metabolism ; Selenium/therapeutic use ; tau Proteins/metabolism
Czasopismo naukowe
Tytuł :
Synthesis and evaluation of multi-target-directed ligands with BACE-1 inhibitory and Nrf2 agonist activities as potential agents against Alzheimer's disease.
Autorzy :
Qu L; Jiangsu Key Laboratory of Bioactive Natural Product Research and State Key Laboratory of Natural Medicines, Department of Natural Medicinal Chemistry, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, 210009, China.
Ji L; Jiangsu Key Laboratory of Bioactive Natural Product Research and State Key Laboratory of Natural Medicines, Department of Natural Medicinal Chemistry, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, 210009, China.
Wang C; Jiangsu Key Laboratory of Bioactive Natural Product Research and State Key Laboratory of Natural Medicines, Department of Natural Medicinal Chemistry, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, 210009, China.
Luo H; Jiangsu Key Laboratory of Bioactive Natural Product Research and State Key Laboratory of Natural Medicines, Department of Natural Medicinal Chemistry, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, 210009, China.
Li S; Jiangsu Key Laboratory of Bioactive Natural Product Research and State Key Laboratory of Natural Medicines, Department of Natural Medicinal Chemistry, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, 210009, China.
Peng W; Jiangsu Key Laboratory of Bioactive Natural Product Research and State Key Laboratory of Natural Medicines, Department of Natural Medicinal Chemistry, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, 210009, China.
Yin F; Jiangsu Key Laboratory of Bioactive Natural Product Research and State Key Laboratory of Natural Medicines, Department of Natural Medicinal Chemistry, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, 210009, China.
Lu D; Jiangsu Key Laboratory of Bioactive Natural Product Research and State Key Laboratory of Natural Medicines, Department of Natural Medicinal Chemistry, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, 210009, China.
Liu X; Jiangsu Key Laboratory of Bioactive Natural Product Research and State Key Laboratory of Natural Medicines, Department of Natural Medicinal Chemistry, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, 210009, China.
Kong L; Jiangsu Key Laboratory of Bioactive Natural Product Research and State Key Laboratory of Natural Medicines, Department of Natural Medicinal Chemistry, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, 210009, China. Electronic address: .
Wang X; Jiangsu Key Laboratory of Bioactive Natural Product Research and State Key Laboratory of Natural Medicines, Department of Natural Medicinal Chemistry, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, 210009, China. Electronic address: .
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Źródło :
European journal of medicinal chemistry [Eur J Med Chem] 2021 Jul 05; Vol. 219, pp. 113441. Date of Electronic Publication: 2021 Apr 07.
Typ publikacji :
Journal Article
MeSH Terms :
Ligands*
Amyloid Precursor Protein Secretases/*antagonists & inhibitors
Aspartic Acid Endopeptidases/*antagonists & inhibitors
NF-E2-Related Factor 2/*antagonists & inhibitors
Neuroprotective Agents/*chemical synthesis
Alzheimer Disease/drug therapy ; Amyloid Precursor Protein Secretases/metabolism ; Amyloid beta-Peptides/metabolism ; Antioxidants/metabolism ; Aspartic Acid Endopeptidases/metabolism ; Azoles/chemistry ; Azoles/metabolism ; Azoles/pharmacology ; Azoles/therapeutic use ; Binding Sites ; Blood-Brain Barrier/drug effects ; Blood-Brain Barrier/metabolism ; Cyclic S-Oxides/chemistry ; Cyclic S-Oxides/metabolism ; Cyclic S-Oxides/pharmacology ; Cyclic S-Oxides/therapeutic use ; Drug Design ; Humans ; Interleukin-6/metabolism ; Mitochondria/drug effects ; Mitochondria/metabolism ; Molecular Docking Simulation ; NF-E2-Related Factor 2/metabolism ; Neuroprotective Agents/metabolism ; Neuroprotective Agents/pharmacology ; Neuroprotective Agents/therapeutic use ; Organoselenium Compounds/chemistry ; Organoselenium Compounds/metabolism ; Organoselenium Compounds/pharmacology ; Organoselenium Compounds/therapeutic use ; Oxidative Stress/drug effects ; Peptide Fragments/metabolism ; Reactive Oxygen Species/metabolism ; Selenium/chemistry ; Signal Transduction/drug effects ; Thiadiazines/chemistry ; Thiadiazines/metabolism ; Thiadiazines/pharmacology ; Thiadiazines/therapeutic use
Czasopismo naukowe
Tytuł :
Round Scad-Derived Octapeptide WCPFSRSF Confers Neuroprotection by Regulating Akt/Nrf2/NFκB Signaling.
Autorzy :
Zhang Q; School of Food Science and Engineering, South China University of Technology, Guangzhou 510640, China.; Guangdong Food Green Processing and Nutrition Regulation Technologies Research Center, Guangzhou 510650, China.
Su G; School of Food Science and Engineering, South China University of Technology, Guangzhou 510640, China.; Guangdong Food Green Processing and Nutrition Regulation Technologies Research Center, Guangzhou 510650, China.
Yang Q; National and Local United Engineering Lab of Marine Functional Food, Rongcheng Taixiang Food Products Co., Ltd, Weihai 264200, China.
Wei Z; National and Local United Engineering Lab of Marine Functional Food, Rongcheng Taixiang Food Products Co., Ltd, Weihai 264200, China.
Wang J; National and Local United Engineering Lab of Marine Functional Food, Rongcheng Taixiang Food Products Co., Ltd, Weihai 264200, China.
Zheng L; School of Food Science and Engineering, South China University of Technology, Guangzhou 510640, China.; Guangdong Food Green Processing and Nutrition Regulation Technologies Research Center, Guangzhou 510650, China.
Zhao M; School of Food Science and Engineering, South China University of Technology, Guangzhou 510640, China.; Guangdong Food Green Processing and Nutrition Regulation Technologies Research Center, Guangzhou 510650, China.
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Źródło :
Journal of agricultural and food chemistry [J Agric Food Chem] 2021 Sep 15; Vol. 69 (36), pp. 10606-10616. Date of Electronic Publication: 2021 Sep 05.
Typ publikacji :
Journal Article
MeSH Terms :
NF-E2-Related Factor 2*/genetics
NF-E2-Related Factor 2*/metabolism
Neuroprotective Agents*/pharmacology
Animals ; Antioxidants/pharmacology ; Mice ; Neuroprotection ; Oxidative Stress ; Proto-Oncogene Proteins c-akt/genetics ; Proto-Oncogene Proteins c-akt/metabolism ; Reactive Oxygen Species ; Signal Transduction
Czasopismo naukowe
Tytuł :
Neuroprotective Action of Multitarget 7-Aminophenanthridin-6( 5H )-one Derivatives against Metal-Induced Cell Death and Oxidative Stress in SN56 Cells.
Autorzy :
Moyano P; Departamento de Farmacología y Toxicología, Facultad de Veterinaria, Universidad Complutense, 28040 Madrid, Spain.
Vicente-Zurdo D; Departamento de Química Analítica, Facultad de Ciencias Químicas, Universidad Complutense, 28040 Madrid, Spain.
Blázquez-Barbadillo C; Unidad de Química Orgánica y Farmacéutica, Departamento de Química en Ciencias Farmacéuticas, Facultad de Farmacia, Universidad Complutense, 28040 Madrid, Spain.
Menéndez JC; Unidad de Química Orgánica y Farmacéutica, Departamento de Química en Ciencias Farmacéuticas, Facultad de Farmacia, Universidad Complutense, 28040 Madrid, Spain.
González JF; Unidad de Química Orgánica y Farmacéutica, Departamento de Química en Ciencias Farmacéuticas, Facultad de Farmacia, Universidad Complutense, 28040 Madrid, Spain.
Rosales-Conrado N; Departamento de Química Analítica, Facultad de Ciencias Químicas, Universidad Complutense, 28040 Madrid, Spain.
Del Pino J; Departamento de Farmacología y Toxicología, Facultad de Veterinaria, Universidad Complutense, 28040 Madrid, Spain.
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Źródło :
ACS chemical neuroscience [ACS Chem Neurosci] 2021 Sep 15; Vol. 12 (18), pp. 3358-3372. Date of Electronic Publication: 2021 Aug 30.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Neuroprotective Agents*/pharmacology
Oxidative Stress*
Antioxidants/pharmacology ; Cell Death ; NF-E2-Related Factor 2/metabolism ; Neuroprotection
Czasopismo naukowe
Tytuł :
Neuroprotective effects of exercise on the aging human neuromuscular system.
Autorzy :
Allen MD; Department of Physical Medicine and Rehabilitation, School of Medicine, Faculty of Health Sciences, Queen's University, Kingston, ON K7L 4X3, Canada; School of Kinesiology and Health Studies, Faculty of Arts and Sciences, Queen's University, Kingston, ON K7L 4X3, Canada.
Dalton BH; School of Health and Exercise Science, University of British Columbia, Kelowna, BC V1V 1V7, Canada.
Gilmore KJ; Department of Surgery, Faculty of Medicine, University of Toronto, Toronto, ON M5S 3E1, Canada.
McNeil CJ; School of Health and Exercise Science, University of British Columbia, Kelowna, BC V1V 1V7, Canada.
Doherty TJ; Department of Clinical Neurological Sciences, Schulich School of Medicine and Dentistry, The University of Western Ontario, London, ON, Canada; Department of Physical Medicine and Rehabilitation, Schulich School of Medicine and Dentistry, The University of Western Ontario, London, ON, Canada.
Rice CL; School of Kinesiology, The University of Western Ontario, London, ON, Canada; Department of Anatomy and Cell Biology, Schulich School of Medicine and Dentistry, The University of Western Ontario, London, ON, Canada. Electronic address: .
Power GA; Department of Human Health and Nutritional Sciences, College of Biological Sciences, University of Guelph, Guelph, ON N1G 2W1, Canada.
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Źródło :
Experimental gerontology [Exp Gerontol] 2021 Sep; Vol. 152, pp. 111465. Date of Electronic Publication: 2021 Jul 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Neuroprotective Agents*
Aged, 80 and over ; Aging ; Animals ; Exercise ; Humans ; Motor Neurons ; Muscle Fibers, Skeletal ; Muscle, Skeletal
Czasopismo naukowe
Tytuł :
Prasugrel anti-ischemic effect in rats: Modulation of hippocampal SUMO2/3-IкBα/Ubc9 and SIRT-1/miR-22 trajectories.
Autorzy :
Gomaa AA; Department of Pharmacology, Faculty of Pharmacy, Ahram Canadian University, Giza, Egypt.
El-Abhar HS; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Cairo University, Cairo, Egypt.
Abdallah DM; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Cairo University, Cairo, Egypt. Electronic address: .
Awad AS; Department of Pharmacology, Faculty of Pharmacy, Ahram Canadian University, Giza, Egypt.
Soubh AA; Department of Pharmacology, Faculty of Pharmacy, Ahram Canadian University, Giza, Egypt.
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Źródło :
Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 2021 Sep 01; Vol. 426, pp. 115635. Date of Electronic Publication: 2021 Jun 24.
Typ publikacji :
Journal Article
MeSH Terms :
Brain Ischemia/*drug therapy
Hippocampus/*drug effects
Neuroprotective Agents/*therapeutic use
Platelet Aggregation Inhibitors/*therapeutic use
Prasugrel Hydrochloride/*therapeutic use
Purinergic P2Y Receptor Antagonists/*therapeutic use
Animals ; Behavior, Animal/drug effects ; Brain Ischemia/blood ; Brain Ischemia/metabolism ; Brain Ischemia/pathology ; Hippocampus/metabolism ; Hippocampus/pathology ; Lipid Peroxidation/drug effects ; Male ; MicroRNAs/blood ; NF-KappaB Inhibitor alpha/metabolism ; Neuroprotective Agents/pharmacology ; Platelet Aggregation Inhibitors/pharmacology ; Prasugrel Hydrochloride/pharmacology ; Purinergic P2Y Receptor Antagonists/pharmacology ; Rats, Wistar ; Sirtuin 1/metabolism ; Small Ubiquitin-Related Modifier Proteins/metabolism ; Spatial Memory/drug effects ; Ubiquitin-Conjugating Enzymes/metabolism
Czasopismo naukowe
Tytuł :
The protective effect and mechanism of COA-Cl in acute phase after spinal cord injury.
Autorzy :
Sakamoto I; Department of Physiology 2, Kawasaki Medical School, Matsushima, Kurashiki, Okayama, Japan; Department of Orthopedic Surgery, Kawasaki Medical School, Matsushima, Kurashiki, Okayama, Japan.
Himi N; Department of Physiology 2, Kawasaki Medical School, Matsushima, Kurashiki, Okayama, Japan. Electronic address: .
Hayashi N; Department of Physiology 2, Kawasaki Medical School, Matsushima, Kurashiki, Okayama, Japan; Department of Orthopedic Surgery, Kawasaki Medical School, Matsushima, Kurashiki, Okayama, Japan.
Okabe N; Department of Physiology 2, Kawasaki Medical School, Matsushima, Kurashiki, Okayama, Japan.
Nakamura-Maruyama E; Department of Physiology 2, Kawasaki Medical School, Matsushima, Kurashiki, Okayama, Japan.
Tsukamoto I; Department of Pharmaco-bio-informatics, Kagawa University Faculty of Medicine, Miki, Kagawa, Japan.
Hasegawa T; Department of Orthopedic Surgery, Kawasaki Medical School, Matsushima, Kurashiki, Okayama, Japan.
Miyamoto O; Department of Physiology 2, Kawasaki Medical School, Matsushima, Kurashiki, Okayama, Japan.
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Źródło :
Neuroscience research [Neurosci Res] 2021 Sep; Vol. 170, pp. 114-121. Date of Electronic Publication: 2020 Dec 11.
Typ publikacji :
Journal Article
MeSH Terms :
Neuroprotective Agents*/pharmacology
Spinal Cord Injuries*/drug therapy
Animals ; Apoptosis ; Coenzyme A/pharmacology ; Disease Models, Animal ; Rats ; Rats, Sprague-Dawley ; Recovery of Function ; Spinal Cord
Czasopismo naukowe
Tytuł :
Phloroglucinol-derived lipids from the leaves of Syzygium cumini and their neuroprotective activities.
Autorzy :
Song JG; Center for Bioactive Natural Molecules and Innovative Drugs Research, College of Pharmacy, Jinan University, Guangzhou 510632, People's Republic of China; Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM & New Drugs Research, Jinan University, Guangzhou 510632, People's Republic of China.
Tang W; Center for Bioactive Natural Molecules and Innovative Drugs Research, College of Pharmacy, Jinan University, Guangzhou 510632, People's Republic of China; Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM & New Drugs Research, Jinan University, Guangzhou 510632, People's Republic of China.
Wang X; Center for Bioactive Natural Molecules and Innovative Drugs Research, College of Pharmacy, Jinan University, Guangzhou 510632, People's Republic of China; Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM & New Drugs Research, Jinan University, Guangzhou 510632, People's Republic of China.
Su JC; Center for Bioactive Natural Molecules and Innovative Drugs Research, College of Pharmacy, Jinan University, Guangzhou 510632, People's Republic of China; Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM & New Drugs Research, Jinan University, Guangzhou 510632, People's Republic of China.
Huang XJ; Center for Bioactive Natural Molecules and Innovative Drugs Research, College of Pharmacy, Jinan University, Guangzhou 510632, People's Republic of China; Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM & New Drugs Research, Jinan University, Guangzhou 510632, People's Republic of China.
Shi L; Center for Bioactive Natural Molecules and Innovative Drugs Research, College of Pharmacy, Jinan University, Guangzhou 510632, People's Republic of China; Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM & New Drugs Research, Jinan University, Guangzhou 510632, People's Republic of China.
Ye WC; Center for Bioactive Natural Molecules and Innovative Drugs Research, College of Pharmacy, Jinan University, Guangzhou 510632, People's Republic of China; Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM & New Drugs Research, Jinan University, Guangzhou 510632, People's Republic of China. Electronic address: .
Wang Y; Center for Bioactive Natural Molecules and Innovative Drugs Research, College of Pharmacy, Jinan University, Guangzhou 510632, People's Republic of China; Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM & New Drugs Research, Jinan University, Guangzhou 510632, People's Republic of China. Electronic address: .
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Źródło :
Fitoterapia [Fitoterapia] 2021 Sep; Vol. 153, pp. 104968. Date of Electronic Publication: 2021 Jun 18.
Typ publikacji :
Journal Article
MeSH Terms :
Lipids/*pharmacology
Neuroprotective Agents/*pharmacology
Phloroglucinol/*chemistry
Syzygium/*chemistry
Animals ; Cell Line ; China ; Lipids/isolation & purification ; Mice ; Molecular Structure ; Neuroprotective Agents/isolation & purification ; Phytochemicals/isolation & purification ; Phytochemicals/pharmacology ; Plant Leaves/chemistry
Czasopismo naukowe
Tytuł :
Discovery of eudesmane-type sesquiterpenoids with neuroprotective effects from the roots of Chloranthus serratus.
Autorzy :
Chen FY; School of Pharmacy, Jiangxi University of Chinese Medicine, Nanchang 330004, People's Republic of China.
Yu WW; School of Pharmacy, Jiangxi University of Chinese Medicine, Nanchang 330004, People's Republic of China.
Huang JW; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, People's Republic of China.
Huang WM; School of Pharmacy, Jiangxi University of Chinese Medicine, Nanchang 330004, People's Republic of China.
Bian YT; School of Pharmacy, Jiangxi University of Chinese Medicine, Nanchang 330004, People's Republic of China.
Shuang PC; School of Pharmacy, Jiangxi University of Chinese Medicine, Nanchang 330004, People's Republic of China.
Luo YM; School of Pharmacy, Jiangxi University of Chinese Medicine, Nanchang 330004, People's Republic of China. Electronic address: .
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Źródło :
Fitoterapia [Fitoterapia] 2021 Sep; Vol. 153, pp. 104971. Date of Electronic Publication: 2021 Jun 21.
Typ publikacji :
Journal Article
MeSH Terms :
Magnoliopsida/*chemistry
Neuroprotective Agents/*pharmacology
Sesquiterpenes, Eudesmane/*pharmacology
Animals ; China ; Molecular Structure ; Neuroprotective Agents/isolation & purification ; PC12 Cells ; Phytochemicals/isolation & purification ; Phytochemicals/pharmacology ; Plant Roots/chemistry ; Rats ; Sesquiterpenes, Eudesmane/isolation & purification
Czasopismo naukowe
Tytuł :
Pharmacological management of secondary spinal cord injury.
Autorzy :
Baroncini A; Department of Orthopaedic Surgery, RWTH Aachen University Clinic, Aachen, Germany.
Maffulli N; Department of Medicine, Surgery and Dentistry, University of Salerno, Baronissi, Italy.; School of Pharmacy and Bioengineering, Keele University School of Medicine, Stoke on Trent, UK.; Centre for Sports and Exercise Medicine, Mile End Hospital, Queen Mary University of London, Barts and the London School of Medicine and Dentistry, London, UK.
Eschweiler J; Department of Orthopaedic Surgery, RWTH Aachen University Clinic, Aachen, Germany.
Tingart M; Department of Orthopaedic Surgery, RWTH Aachen University Clinic, Aachen, Germany.
Migliorini F; Department of Orthopaedic Surgery, RWTH Aachen University Clinic, Aachen, Germany.
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Źródło :
Expert opinion on pharmacotherapy [Expert Opin Pharmacother] 2021 Sep; Vol. 22 (13), pp. 1793-1800. Date of Electronic Publication: 2021 Apr 25.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Neuroprotective Agents*/therapeutic use
Spinal Cord Injuries*/drug therapy
Humans ; Neurons
Czasopismo naukowe
Tytuł :
Neuroprotective effect of targeted regulatory Nrf2 gene on rats with acute brain injury induced by carbon monoxide poisoning.
Autorzy :
Zhou XD; Emergency Department, Shenzhen University General Hospital, Shenzhen, China.
Wang JL; Emergency Center, Yuhuangding Hospital Affiliated to Qingdao University, Yantai, Shandong, China.
Guo DD; Shandong Provincial Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Therapy of Ocular Diseases, Eye Institute of Shandong University of Traditional Chinese Medicine, Jinan, Shandong, China.
Jiang WW; Centre of Integrated Chinese and Western Medicine, School of Basic Medicine, Qingdao University, Qingdao, China.
Li ZK; Emergency Department, Shenzhen University General Hospital, Shenzhen, China.; Centre of Integrated Chinese and Western Medicine, School of Basic Medicine, Qingdao University, Qingdao, China.
Wang L; Emergency Center, Yuhuangding Hospital Affiliated to Qingdao University, Yantai, Shandong, China.
Zou Y; Emergency Center, Yuhuangding Hospital Affiliated to Qingdao University, Yantai, Shandong, China.
Bi MJ; Emergency Center, Yuhuangding Hospital Affiliated to Qingdao University, Yantai, Shandong, China.
Li Q; Emergency Department, Shenzhen University General Hospital, Shenzhen, China.
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Źródło :
Environmental toxicology [Environ Toxicol] 2021 Sep; Vol. 36 (9), pp. 1742-1757. Date of Electronic Publication: 2021 May 25.
Typ publikacji :
Journal Article
MeSH Terms :
Brain Injuries*/chemically induced
Brain Injuries*/genetics
Carbon Monoxide Poisoning*/genetics
NF-E2-Related Factor 2*/genetics
NF-E2-Related Factor 2*/metabolism
Neuroprotective Agents*/pharmacology
Animals ; Oxidative Stress ; Rats
Czasopismo naukowe
Tytuł :
Disassembly of Death-associated Protein Kinase and DANGER Interaction Mediates Hippocampal CA1 Neuron Death in Rat Cerebral Ischemic Reperfusion.
Autorzy :
Lu F; Jiangsu Key Laboratory of Brain Disease Bioinformation, Xuzhou Medical University, Jiangsu, China; Research Center for Biochemistry and Molecular Biology, Xuzhou Medical University, Jiangsu, China.
Xu X; Jiangsu Key Laboratory of Brain Disease Bioinformation, Xuzhou Medical University, Jiangsu, China; Research Center for Biochemistry and Molecular Biology, Xuzhou Medical University, Jiangsu, China.
Yang G; Jiangsu Key Laboratory of Brain Disease Bioinformation, Xuzhou Medical University, Jiangsu, China; Research Center for Biochemistry and Molecular Biology, Xuzhou Medical University, Jiangsu, China.
Hong X; Jiangsu Key Laboratory of Brain Disease Bioinformation, Xuzhou Medical University, Jiangsu, China; Research Center for Biochemistry and Molecular Biology, Xuzhou Medical University, Jiangsu, China.
Chen L; Jiangsu Key Laboratory of Brain Disease Bioinformation, Xuzhou Medical University, Jiangsu, China; Research Center for Biochemistry and Molecular Biology, Xuzhou Medical University, Jiangsu, China.
Yin X; Jiangsu Key Laboratory of Brain Disease Bioinformation, Xuzhou Medical University, Jiangsu, China; Research Center for Biochemistry and Molecular Biology, Xuzhou Medical University, Jiangsu, China.
Yan J; Jiangsu Key Laboratory of Brain Disease Bioinformation, Xuzhou Medical University, Jiangsu, China; Research Center for Biochemistry and Molecular Biology, Xuzhou Medical University, Jiangsu, China.
Li C; Jiangsu Key Laboratory of Brain Disease Bioinformation, Xuzhou Medical University, Jiangsu, China; Research Center for Biochemistry and Molecular Biology, Xuzhou Medical University, Jiangsu, China. Electronic address: .
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Źródło :
Neuroscience [Neuroscience] 2021 Sep 01; Vol. 471, pp. 11-19. Date of Electronic Publication: 2021 Jul 21.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Brain Ischemia*
Neuroprotective Agents*/pharmacology
Reperfusion Injury*
Animals ; CA1 Region, Hippocampal ; Cell Death ; Death-Associated Protein Kinases/pharmacology ; Hippocampus ; Neurons ; Rats ; Reperfusion
Czasopismo naukowe
Tytuł :
The Effect of Monosodium Glutamate on Neuronal Signaling Molecules in the Hippocampus and the Neuroprotective Effects of Omega-3 Fatty Acids.
Autorzy :
Gürgen SG; Department of Histology and Embryology, School of Vocational Health Service, Manisa Celal Bayar University, Manisa 45140, Turkey.
Sayın O; Department of Biochemistry, School of Vocational Health Service, Dokuz Eylul University, İzmir 35330, Turkey.
Çeti N F; Department of Physiology, Faculty of Medicine, Istanbul Medeniyet University, Istanbul 34700, Turkey.
Sarsmaz HY; Department of Histology and Embryology, Faculty of Health Science, Manisa Celal Bayar University, Manisa 45140, Turkey.
Yazıcı GN; Department of Histology and Embryology, Faculty of Medicine, Erzincan University, Erzincan 24100, Turkey.
Umur N; Department of Molecular Biology, School of Vocational Health Service, Manisa Celal Bayar University, Manisa 45140, Turkey.
Yücel AT; Department of Anatomy, School of Vocational Health Service, Manisa Celal Bayar University, Manisa 45140, Turkey.
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Źródło :
ACS chemical neuroscience [ACS Chem Neurosci] 2021 Aug 18; Vol. 12 (16), pp. 3028-3037. Date of Electronic Publication: 2021 Jul 30.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Fatty Acids, Omega-3*/pharmacology
Neuroprotective Agents*/pharmacology
Animals ; Female ; Hippocampus ; Rats ; Rats, Wistar ; Sodium Glutamate
Czasopismo naukowe

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