Temat: "NEUROPROTECTIVE agents" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: TrkB-mediated neuroprotection in female hippocampal neurons is autonomous, estrogen receptor alpha-dependent, and eliminated by testosterone: a proposed model for sex differences in neonatal hippocampal neuronal injury.
Autorzy:: Chanana V; Waisman Center, University of Wisconsin, Madison, WI, USA.; Department of Pediatrics, Division of Pediatric Critical Care Medicine, University of Wisconsin, 1500 Highland Ave - T505, Madison, WI, 53705-9345, USA.
Zafer D; Waisman Center, University of Wisconsin, Madison, WI, USA.; Department of Pediatrics, Division of Pediatric Critical Care Medicine, University of Wisconsin, 1500 Highland Ave - T505, Madison, WI, 53705-9345, USA.
Kintner DB; Waisman Center, University of Wisconsin, Madison, WI, USA.; Department of Pediatrics, Division of Pediatric Critical Care Medicine, University of Wisconsin, 1500 Highland Ave - T505, Madison, WI, 53705-9345, USA.
Chandrashekhar JH; Waisman Center, University of Wisconsin, Madison, WI, USA.; University of Illinois at Urbana-Champaign, Champaign, IL, USA.
Eickhoff J; Department of Statistics and Bioinformatics, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.
Ferrazzano PA; Waisman Center, University of Wisconsin, Madison, WI, USA.; Department of Pediatrics, Division of Pediatric Critical Care Medicine, University of Wisconsin, 1500 Highland Ave - T505, Madison, WI, 53705-9345, USA.
Levine JE; Department of Neuroscience, University of Wisconsin, Madison, WI, USA.; Wisconsin National Primate Research Center, Madison, WI, USA.
Cengiz P; Waisman Center, University of Wisconsin, Madison, WI, USA. .; Department of Pediatrics, Division of Pediatric Critical Care Medicine, University of Wisconsin, 1500 Highland Ave - T505, Madison, WI, 53705-9345, USA. .; Pokaż więcej
Źródło:: Biology of sex differences [Biol Sex Differ] 2024 Apr 02; Vol. 15 (1), pp. 30. Date of Electronic Publication: 2024 Apr 02.
Typ publikacji:: Journal Article
MeSH Terms:: Estrogen Receptor alpha*/metabolism
Neuroprotective Agents*/pharmacology
Neuroprotective Agents*/metabolism
Child ; Female ; Animals ; Male ; Mice ; Humans ; Neuroprotection ; Sex Characteristics ; Testosterone/pharmacology ; Testosterone/metabolism ; Neurons/metabolism ; Hippocampus/metabolism ; Ischemia ; Hypoxia/metabolism ; RNA, Messenger/metabolism

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Skocz do pozycji: 2.

Tytuł:: The neuroprotective effect of human primary astrocytes in multiple sclerosis: In vitro model.
Autorzy:: Imraish A; Department of Biological Sciences, School of Science, The University of Jordan, Amman, Jordan.
Abu Thiab T; Department of Biological Sciences, School of Science, The University of Jordan, Amman, Jordan.
Alsalem M; Department of Anatomy and Histology, School of Medicine, The University of Jordan, Amman, Jordan.
Dahbour S; Department of Neurology, Jordan University Hospital, The University of Jordan, Amman, Jordan.
Khleif H; Department of Biological Sciences, School of Science, The University of Jordan, Amman, Jordan.
Abu-Irmaileh B; Hamdi Mango Centre for Scientific Research, The University of Jordan, Amman, Jordan.
Qasem R; Department of Biological Sciences, School of Science, The University of Jordan, Amman, Jordan.
El-Salem K; Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2024 Apr 02; Vol. 19 (4), pp. e0300203. Date of Electronic Publication: 2024 Apr 02 (Print Publication: 2024).
Typ publikacji:: Journal Article
MeSH Terms:: Neuroprotective Agents*/pharmacology
Neuroprotective Agents*/metabolism
Multiple Sclerosis*/pathology
Humans ; Astrocytes/metabolism ; Inflammation/pathology ; Tumor Necrosis Factor-alpha/metabolism

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Skocz do pozycji: 3.

Tytuł:: Retinoic acid attenuates ischemic injury-induced activation of glial cells and inflammatory factors in a rat stroke model.
Autorzy:: Kang JB; Department of Anatomy and Histology, College of Veterinary Medicine, Research Institute of Life Science, Gyeongsang National University, Jinju, South Korea.
Son HK; Department of Anatomy and Histology, College of Veterinary Medicine, Research Institute of Life Science, Gyeongsang National University, Jinju, South Korea.
Shah MA; Department of Anatomy and Histology, College of Veterinary Medicine, Research Institute of Life Science, Gyeongsang National University, Jinju, South Korea.
Koh PO; Department of Anatomy and Histology, College of Veterinary Medicine, Research Institute of Life Science, Gyeongsang National University, Jinju, South Korea.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2024 Mar 25; Vol. 19 (3), pp. e0300072. Date of Electronic Publication: 2024 Mar 25 (Print Publication: 2024).
Typ publikacji:: Journal Article
MeSH Terms:: Stroke*/drug therapy
Stroke*/metabolism
Brain Ischemia*/drug therapy
Neuroprotective Agents*/pharmacology
Neuroprotective Agents*/therapeutic use
Rats ; Male ; Animals ; Tumor Necrosis Factor-alpha/metabolism ; Tretinoin/pharmacology ; Tretinoin/therapeutic use ; Antioxidants/pharmacology ; Antioxidants/therapeutic use ; Neuroglia/metabolism ; Cytokines/metabolism ; Anti-Inflammatory Agents/therapeutic use ; Infarction, Middle Cerebral Artery/complications ; Infarction, Middle Cerebral Artery/drug therapy ; Infarction, Middle Cerebral Artery/pathology

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Skocz do pozycji: 4.

Tytuł:: Neuroprotective Effects of Aucubin against Cerebral Ischemia and Ischemia Injury through the Inhibition of the TLR4/NF-κB Inflammatory Signaling Pathway in Gerbils.
Autorzy:: Park JH; Department of Anatomy, College of Korean Medicine, Dongguk University, Gyeongju 38066, Republic of Korea.
Lee TK; Department of Food Science and Nutrition, Hallym University, Chuncheon 24252, Republic of Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung 25457, Republic of Korea.
Ahn JH; Department of Physical Therapy, College of Health Science, Youngsan University, Yangsan 50510, Republic of Korea.
Shin MC; Department of Emergency Medicine, Kangwon National University Hospital, School of Medicine, Kangwon National University, Chuncheon 24289, Republic of Korea.
Cho JH; Department of Emergency Medicine, Kangwon National University Hospital, School of Medicine, Kangwon National University, Chuncheon 24289, Republic of Korea.
Won MH; Department of Emergency Medicine, Kangwon National University Hospital, School of Medicine, Kangwon National University, Chuncheon 24289, Republic of Korea.
Kang IJ; Department of Food Science and Nutrition, Hallym University, Chuncheon 24252, Republic of Korea.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Mar 19; Vol. 25 (6). Date of Electronic Publication: 2024 Mar 19.
Typ publikacji:: Journal Article
MeSH Terms:: Neuroprotective Agents*/pharmacology
Neuroprotective Agents*/therapeutic use
Brain Ischemia*/drug therapy
Brain Ischemia*/metabolism
Reperfusion Injury*/drug therapy
Reperfusion Injury*/metabolism
Iridoid Glucosides*
Animals ; NF-kappa B/metabolism ; NF-KappaB Inhibitor alpha/metabolism ; Gerbillinae/metabolism ; Tumor Necrosis Factor-alpha/metabolism ; Toll-Like Receptor 4/metabolism ; Gliosis ; Signal Transduction ; Ischemia ; Cerebral Infarction

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Skocz do pozycji: 5.

Tytuł:: Erythropoietin-derived peptide ARA290 mediates brain tissue protection through the β-common receptor in mice with cerebral ischemic stroke.
Autorzy:: Wang RL; Institute of Cerebrovascular Diseases Research and Department of Neurology, Xuanwu Hospital of Capital Medical University, Beijing, China.; Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China.; Beijing Key Laboratory of Translational Medicine for Cerebrovascular Diseases, Beijing, China.
Yang ZH; Institute of Cerebrovascular Diseases Research and Department of Neurology, Xuanwu Hospital of Capital Medical University, Beijing, China.
Huang YY; Institute of Cerebrovascular Diseases Research and Department of Neurology, Xuanwu Hospital of Capital Medical University, Beijing, China.
Hu Y; Institute of Cerebrovascular Diseases Research and Department of Neurology, Xuanwu Hospital of Capital Medical University, Beijing, China.
Wang YL; Institute of Cerebrovascular Diseases Research and Department of Neurology, Xuanwu Hospital of Capital Medical University, Beijing, China.
Yan F; Institute of Cerebrovascular Diseases Research and Department of Neurology, Xuanwu Hospital of Capital Medical University, Beijing, China.; Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China.; Beijing Key Laboratory of Translational Medicine for Cerebrovascular Diseases, Beijing, China.
Zheng YM; Institute of Cerebrovascular Diseases Research and Department of Neurology, Xuanwu Hospital of Capital Medical University, Beijing, China.; Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China.; Beijing Key Laboratory of Translational Medicine for Cerebrovascular Diseases, Beijing, China.
Han ZP; Institute of Cerebrovascular Diseases Research and Department of Neurology, Xuanwu Hospital of Capital Medical University, Beijing, China.; Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China.; Beijing Key Laboratory of Translational Medicine for Cerebrovascular Diseases, Beijing, China.
Fan JF; Institute of Cerebrovascular Diseases Research and Department of Neurology, Xuanwu Hospital of Capital Medical University, Beijing, China.; Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China.; Beijing Key Laboratory of Translational Medicine for Cerebrovascular Diseases, Beijing, China.
Tao Z; Institute of Cerebrovascular Diseases Research and Department of Neurology, Xuanwu Hospital of Capital Medical University, Beijing, China.; Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China.; Beijing Key Laboratory of Translational Medicine for Cerebrovascular Diseases, Beijing, China.
Zhao HP; Institute of Cerebrovascular Diseases Research and Department of Neurology, Xuanwu Hospital of Capital Medical University, Beijing, China.; Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China.; Beijing Key Laboratory of Translational Medicine for Cerebrovascular Diseases, Beijing, China.
Li SJ; Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China.; Beijing Key Laboratory of Translational Medicine for Cerebrovascular Diseases, Beijing, China.; Emergency Department, Xuanwu Hospital of Capital Medical University, Beijing, China.
Luo YM; Institute of Cerebrovascular Diseases Research and Department of Neurology, Xuanwu Hospital of Capital Medical University, Beijing, China.; Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China.; Beijing Key Laboratory of Translational Medicine for Cerebrovascular Diseases, Beijing, China.; Pokaż więcej
Źródło:: CNS neuroscience & therapeutics [CNS Neurosci Ther] 2024 Mar; Vol. 30 (3), pp. e14676.
Typ publikacji:: Journal Article
MeSH Terms:: Ischemic Stroke*
Neuroprotective Agents*/pharmacology
Neuroprotective Agents*/therapeutic use
Erythropoietin*/therapeutic use
Stroke*/drug therapy
Stroke*/genetics
Reperfusion Injury*
Brain Ischemia*/drug therapy
Oligopeptides*
Mice ; Male ; Animals ; Mice, Inbred C57BL ; Peptides ; Infarction, Middle Cerebral Artery/drug therapy ; Cytokines ; Brain

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Skocz do pozycji: 6.

Tytuł:: Epigallocatechin gallate improves neuronal damage in animal model of ischemic stroke and glutamate-exposed neurons via modulation of hippocalcin expression.
Autorzy:: Park DJ; Department of Anatomy, College of Veterinary Medicine, Research Institute of Life Science, Gyeongsang National University, Jinju, South Korea.
Kang JB; Department of Anatomy, College of Veterinary Medicine, Research Institute of Life Science, Gyeongsang National University, Jinju, South Korea.
Koh PO; Department of Anatomy, College of Veterinary Medicine, Research Institute of Life Science, Gyeongsang National University, Jinju, South Korea.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2024 Mar 01; Vol. 19 (3), pp. e0299042. Date of Electronic Publication: 2024 Mar 01 (Print Publication: 2024).
Typ publikacji:: Journal Article
MeSH Terms:: Catechin*/analogs & derivatives
Ischemic Stroke*/metabolism
Neuroprotective Agents*/pharmacology
Neuroprotective Agents*/therapeutic use
Animals ; Apoptosis ; Calcium/metabolism ; Caspase 3/metabolism ; Glutamic Acid/metabolism ; Hippocalcin/genetics ; Hippocalcin/metabolism ; Infarction, Middle Cerebral Artery/complications ; Infarction, Middle Cerebral Artery/drug therapy ; Neurons/metabolism ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Disease Models, Animal

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Skocz do pozycji: 7.

Tytuł:: Neuroprotective effects of gemfibrozil in neurological disorders: Focus on inflammation and molecular mechanisms.
Autorzy:: Ivraghi MS; School of Medicine, Qazvin University of Medical Sciences, Qazvin, Iran.
Zamanian MY; Neurophysiology Research Center, Hamadan University of Medical Sciences, Hamadan, Iran.; Department of Pharmacology and Toxicology, School of Pharmacy, Hamadan University of Medical Sciences, Hamadan, Iran.
Gupta R; Institute of Pharmaceutical Research, GLA University, Mathura, India.
Achmad H; Department of Pediatric Dentistry, Faculty of Dentistry, Hasanuddin University, Makassar, Indonesia.
Alsaab HO; Pharmaceutics and Pharmaceutical Technology, Taif University, Taif, Saudi Arabia.
Hjazi A; Department of Medical Laboratory Sciences, College of Applied Medical Sciences, Prince Sattam bin Abdulaziz University, Al-Kharj, Saudi Arabia.
Romero-Parra RM; Universidad Continental, Lima, Peru.
Alwaily ER; Microbiology Research Group, College of Pharmacy, Al-Ayen University, Thi-Qar, Iraq.
Hussien BM; Medical Laboratory Technology Department, College of Medical Technology, The Islamic University, Najaf, Iraq.
Hakimizadeh E; Physiology-Pharmacology Research Center, Research Institute of Basic Medical Sciences, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.; Pokaż więcej
Źródło:: CNS neuroscience & therapeutics [CNS Neurosci Ther] 2024 Mar; Vol. 30 (3), pp. e14473. Date of Electronic Publication: 2023 Oct 30.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Neuroprotective Agents*/pharmacology
Neuroprotective Agents*/therapeutic use
Parkinson Disease*/drug therapy
Animals ; Mice ; Humans ; Gemfibrozil/pharmacology ; Gemfibrozil/therapeutic use ; Inflammation/drug therapy ; PPAR alpha ; Cytokines

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Skocz do pozycji: 8.

Tytuł:: Current state of neuroprotective therapy using antibiotics in human traumatic brain injury and animal models.
Autorzy:: Ritter K; Department of Anesthesiology, University Medical Center, Johannes Gutenberg-University Mainz, Langenbeckstraße 1 (Bld. 505), Mainz, 55131, Germany.
Somnuke P; Department of Anesthesiology, University Medical Center, Johannes Gutenberg-University Mainz, Langenbeckstraße 1 (Bld. 505), Mainz, 55131, Germany.; Department of Anesthesiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, 10700, Thailand.
Hu L; Department of Anesthesiology, University Medical Center, Johannes Gutenberg-University Mainz, Langenbeckstraße 1 (Bld. 505), Mainz, 55131, Germany.; Department of Gastroenterology, Nanxishan Hospital of Guangxi Zhuang Autonomous Region, Guilin, China.
Griemert EV; Department of Anesthesiology, University Medical Center, Johannes Gutenberg-University Mainz, Langenbeckstraße 1 (Bld. 505), Mainz, 55131, Germany.
Schäfer MKE; Department of Anesthesiology, University Medical Center, Johannes Gutenberg-University Mainz, Langenbeckstraße 1 (Bld. 505), Mainz, 55131, Germany. .; Focus Program Translational Neurosciences (FTN, Johannes Gutenberg-University Mainz, Mainz, Germany. .; Research Center for Immunotherapy, University Medical Center, Johannes Gutenberg- University Mainz, Mainz, Germany. .; Pokaż więcej
Źródło:: BMC neuroscience [BMC Neurosci] 2024 Feb 29; Vol. 25 (1), pp. 10. Date of Electronic Publication: 2024 Feb 29.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Brain Injuries, Traumatic*/drug therapy
Brain Injuries, Traumatic*/complications
Brain Injuries*
Neuroprotective Agents*/pharmacology
Neuroprotective Agents*/therapeutic use
Animals ; Humans ; Aged ; Adolescent ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use ; Disease Models, Animal

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Skocz do pozycji: 9.

Tytuł:: Sodium butyrate exerts a neuroprotective effect in rats with acute carbon monoxide poisoning by activating autophagy through the mTOR signaling pathway.
Autorzy:: Wen J; Department of Emergency, Affiliated Hospital of North Sichuan Medical College, Nanchong, 637000, China.; North Sichuan Medical College Innovation Center for Science and Technology, Nanchong, 637000, China.
Xu Q; Department of General Medicine, Affiliated Hospital of North Sichuan Medical College, Nanchong, 637000, China.
Li J; Department of General Medicine, Affiliated Hospital of North Sichuan Medical College, Nanchong, 637000, China.
Shen X; Department of Emergency, Affiliated Hospital of North Sichuan Medical College, Nanchong, 637000, China.; North Sichuan Medical College Innovation Center for Science and Technology, Nanchong, 637000, China.
Zhou X; Department of General Medicine, Affiliated Hospital of North Sichuan Medical College, Nanchong, 637000, China.
Huang J; North Sichuan Medical College Innovation Center for Science and Technology, Nanchong, 637000, China.
Liu S; Department of General Medicine, Affiliated Hospital of North Sichuan Medical College, Nanchong, 637000, China. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Feb 26; Vol. 14 (1), pp. 4610. Date of Electronic Publication: 2024 Feb 26.
Typ publikacji:: Journal Article
MeSH Terms:: Neuroprotective Agents*/pharmacology
Neuroprotective Agents*/therapeutic use
Carbon Monoxide Poisoning*/drug therapy
Carbon Monoxide Poisoning*/complications
Brain Diseases*/pathology
Brain Injuries*/complications
Rats ; Animals ; Butyric Acid/pharmacology ; Butyric Acid/therapeutic use ; Signal Transduction ; TOR Serine-Threonine Kinases/metabolism ; Autophagy

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Skocz do pozycji: 10.

Tytuł:: Neuroprotective Effects of the Nutraceutical Dehydrozingerone and Its C 2 -Symmetric Dimer in a Drosophila Model of Parkinson's Disease.
Autorzy:: Setzu MD; Department of Biomedical Sciences, University of Cagliari, Monserrato, 09042 Cagliari, Italy.
Mocci I; Unit of Cagliari, CNR-Institute of Translational Pharmacology, Pula, 09050 Cagliari, Italy.
Fabbri D; Unit of Sassari, CNR-Institute of Biomolecular Chemistry, 07100 Sassari, Italy.
Carta P; Unit of Sassari, CNR-Institute of Biomolecular Chemistry, 07100 Sassari, Italy.
Muroni P; Department of Biomedical Sciences, University of Cagliari, Monserrato, 09042 Cagliari, Italy.
Diana A; Department of Biomedical Sciences, University of Cagliari, Monserrato, 09042 Cagliari, Italy.
Dettori MA; Unit of Sassari, CNR-Institute of Biomolecular Chemistry, 07100 Sassari, Italy.
Casu MA; Unit of Cagliari, CNR-Institute of Translational Pharmacology, Pula, 09050 Cagliari, Italy.; Pokaż więcej
Źródło:: Biomolecules [Biomolecules] 2024 Feb 24; Vol. 14 (3). Date of Electronic Publication: 2024 Feb 24.
Typ publikacji:: Journal Article
MeSH Terms:: Parkinson Disease*/drug therapy
Parkinson Disease*/genetics
Neuroprotective Agents*/pharmacology
Neuroprotective Agents*/therapeutic use
Disabled Persons*
Motor Disorders*
Styrenes*
Animals ; Humans ; Drosophila ; Drosophila melanogaster/genetics ; Dopaminergic Neurons ; Dietary Supplements ; Mutation

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Skocz do pozycji: 11.

Tytuł:: An Update of Kaempferol Protection against Brain Damage Induced by Ischemia-Reperfusion and by 3-Nitropropionic Acid.
Autorzy:: López-Sánchez C; Institute of Molecular Pathology Biomarkers, University of Extremadura, 06006 Badajoz, Spain.; Department of Human Anatomy and Embryology, Faculty of Medicine and Health Sciences, University of Extremadura, 06006 Badajoz, Spain.
Lagoa R; School of Technology and Management, Polytechnic Institute of Leiria, Morro do Lena-Alto do Vieiro, 2411-901 Leiria, Portugal.; Laboratory of Separation and Reaction Engineering-Laboratory of Catalysis and Materials (LSRE-LCM), Polytechnic Institute of Leiria, 2411-901 Leiria, Portugal.
Poejo J; Institute of Molecular Pathology Biomarkers, University of Extremadura, 06006 Badajoz, Spain.
García-López V; Institute of Molecular Pathology Biomarkers, University of Extremadura, 06006 Badajoz, Spain.; Department of Medical and Surgical Therapeutics, Pharmacology Area, Faculty of Medicine and Health Sciences, University of Extremadura, 06006 Badajoz, Spain.
García-Martínez V; Institute of Molecular Pathology Biomarkers, University of Extremadura, 06006 Badajoz, Spain.; Department of Human Anatomy and Embryology, Faculty of Medicine and Health Sciences, University of Extremadura, 06006 Badajoz, Spain.
Gutierrez-Merino C; Institute of Molecular Pathology Biomarkers, University of Extremadura, 06006 Badajoz, Spain.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2024 Feb 08; Vol. 29 (4). Date of Electronic Publication: 2024 Feb 08.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Stroke*/drug therapy
Brain Injuries*/drug therapy
Ischemic Stroke*/drug therapy
Neuroprotective Agents*/pharmacology
Neuroprotective Agents*/therapeutic use
Nitro Compounds*
Propionates*
Animals ; Kaempferols/pharmacology ; Brain ; Oxidative Stress ; Ischemia/drug therapy ; Reperfusion

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Skocz do pozycji: 12.

Tytuł:: Inhibiting acid-sensing ion channel exerts neuroprotective effects in experimental epilepsy via suppressing ferroptosis.
Autorzy:: Shi X; Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; China National Clinical Research Center for Neurological Diseases, Beijing, China.
Liu R; Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; China National Clinical Research Center for Neurological Diseases, Beijing, China.; Advanced Innovation Center for Human Brain Protection, Capital Medical University, Beijing, China.
Wang Y; Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; China National Clinical Research Center for Neurological Diseases, Beijing, China.
Yu T; Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; China National Clinical Research Center for Neurological Diseases, Beijing, China.
Zhang K; Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Zhang C; Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Gu Y; Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Zhang L; Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Wu J; Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; China National Clinical Research Center for Neurological Diseases, Beijing, China.; Advanced Innovation Center for Human Brain Protection, Capital Medical University, Beijing, China.
Wang Q; Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; China National Clinical Research Center for Neurological Diseases, Beijing, China.; Center of Epilepsy, Beijing Institute of Brain Disorders, Collaborative Innovation Center for Brain Disorders, Capital Medical University, Beijing, China.
Zhu F; Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; China National Clinical Research Center for Neurological Diseases, Beijing, China.; Pokaż więcej
Źródło:: CNS neuroscience & therapeutics [CNS Neurosci Ther] 2024 Feb; Vol. 30 (2), pp. e14596.
Typ publikacji:: Journal Article
MeSH Terms:: Neuroprotective Agents*/pharmacology
Neuroprotective Agents*/therapeutic use
Ferroptosis*
Epilepsy*/drug therapy
Humans ; Acid Sensing Ion Channels/metabolism ; Iron/metabolism

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Skocz do pozycji: 13.

Tytuł:: S-9-PAHSA's neuroprotective effect mediated by CAIII suppresses apoptosis and oxidative stress in a mouse model of type 2 diabetes.
Autorzy:: Wang JT; Department of Geriatric Neurology of Huashan Hospital, National Clinical Research Center for Aging and Medicine, Fudan University, Shanghai, China.; Department of General Practice, Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu Province, China.
Wang XR; Department of Geriatric Neurology of Huashan Hospital, National Clinical Research Center for Aging and Medicine, Fudan University, Shanghai, China.
Ren JQ; Department of Geriatric Neurology of Huashan Hospital, National Clinical Research Center for Aging and Medicine, Fudan University, Shanghai, China.
Lin JH; Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.
Yu ZY; Department of Geriatric Neurology of Huashan Hospital, National Clinical Research Center for Aging and Medicine, Fudan University, Shanghai, China.
Huang SS; Department of Geriatric Neurology of Huashan Hospital, National Clinical Research Center for Aging and Medicine, Fudan University, Shanghai, China.
Hu Y; Department of Geriatric Neurology of Huashan Hospital, National Clinical Research Center for Aging and Medicine, Fudan University, Shanghai, China.
Fu JY; Department of Geriatric Neurology of Huashan Hospital, National Clinical Research Center for Aging and Medicine, Fudan University, Shanghai, China.
Wang M; Department of Geriatric Neurology of Huashan Hospital, National Clinical Research Center for Aging and Medicine, Fudan University, Shanghai, China.
Zhang YL; Department of Geriatric Neurology of Huashan Hospital, National Clinical Research Center for Aging and Medicine, Fudan University, Shanghai, China.
Wang XC; Department of Geriatric Neurology of Huashan Hospital, National Clinical Research Center for Aging and Medicine, Fudan University, Shanghai, China.
Guo JC; State Key Laboratory of Medical Neurobiology, MOE Frontier Center for Brain Science, Department of Translational Neuroscience of Shanghai Jing'an District Centre Hospital, Institutes of Brain Science, Fudan University, Shanghai, China.
Xiao JC; Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.
Zhou HG; Department of Geriatric Neurology of Huashan Hospital, National Clinical Research Center for Aging and Medicine, Fudan University, Shanghai, China.; Pokaż więcej
Źródło:: CNS neuroscience & therapeutics [CNS Neurosci Ther] 2024 Feb; Vol. 30 (2), pp. e14594.
Typ publikacji:: Journal Article
MeSH Terms:: Diabetes Mellitus, Type 2*/complications
Diabetes Mellitus, Type 2*/drug therapy
Insulin Resistance*
Neuroprotective Agents*/pharmacology
Neuroprotective Agents*/therapeutic use
Palmitic Acid*
Stearic Acids*
Animals ; Mice ; Rats ; Apoptosis ; Blood Glucose/metabolism ; Diet, High-Fat/adverse effects ; Disease Models, Animal ; Endothelial Cells/metabolism ; Oxidative Stress ; Carbonic Anhydrase III/drug effects ; Carbonic Anhydrase III/metabolism

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Skocz do pozycji: 14.

Tytuł:: The Impact of C-3 Side Chain Modifications on Kynurenic Acid: A Behavioral Analysis of Its Analogs in the Motor Domain.
Autorzy:: Martos D; HUN-REN-SZTE Neuroscience Research Group, Hungarian Research Network, University of Szeged, Danube Neuroscience Research Laboratory, Tisza Lajos krt. 113, H-6725 Szeged, Hungary.
Lőrinczi B; Institute of Pharmaceutical Chemistry and HUN-REN-SZTE Stereochemistry Research Group, University of Szeged, Eötvös u. 6, H-6720 Szeged, Hungary.
Szatmári I; Institute of Pharmaceutical Chemistry and HUN-REN-SZTE Stereochemistry Research Group, University of Szeged, Eötvös u. 6, H-6720 Szeged, Hungary.
Vécsei L; HUN-REN-SZTE Neuroscience Research Group, Hungarian Research Network, University of Szeged, Danube Neuroscience Research Laboratory, Tisza Lajos krt. 113, H-6725 Szeged, Hungary.; Department of Neurology, Albert Szent-Györgyi Medical School, University of Szeged, Semmelweis u. 6, H-6725 Szeged, Hungary.
Tanaka M; HUN-REN-SZTE Neuroscience Research Group, Hungarian Research Network, University of Szeged, Danube Neuroscience Research Laboratory, Tisza Lajos krt. 113, H-6725 Szeged, Hungary.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Mar 16; Vol. 25 (6). Date of Electronic Publication: 2024 Mar 16.
Typ publikacji:: Journal Article
MeSH Terms:: Kynurenic Acid*
Neuroprotective Agents*/chemistry
Blood-Brain Barrier ; Drug Delivery Systems ; Open Field Test

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Skocz do pozycji: 15.

Tytuł:: Understanding the Pathophysiology of Ischemic Stroke: The Basis of Current Therapies and Opportunity for New Ones.
Autorzy:: Salaudeen MA; Division of Neuroscience, Faculty of Biology, Medicine and Health, School of Biological Sciences, University of Manchester, Manchester M13 9PL, UK.; Department of Pharmacology and Therapeutics, Faculty of Pharmaceutical Sciences, Ahmadu Bello University, Zaria 810107, Nigeria.
Bello N; Department of Pharmacology and Therapeutics, Faculty of Pharmaceutical Sciences, Ahmadu Bello University, Zaria 810107, Nigeria.; Department of Pharmacology and Therapeutics, Faculty of Clinical Sciences, College of Health Sciences, Usmanu Danfodiyo University, Sokoto 840001, Nigeria.
Danraka RN; Department of Pharmacology and Therapeutics, Faculty of Pharmaceutical Sciences, Ahmadu Bello University, Zaria 810107, Nigeria.
Ammani ML; Department of Biosciences, School of Science and Technology, Nottingham Trent University, Nottingham NG11 8NS, UK.; Department of Pharmacology and Toxicology, Faculty of Pharmaceutical Sciences, Kaduna State University, Kaduna 800283, Nigeria.; Pokaż więcej
Źródło:: Biomolecules [Biomolecules] 2024 Mar 04; Vol. 14 (3). Date of Electronic Publication: 2024 Mar 04.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Brain Ischemia*/drug therapy
Ischemic Stroke*/drug therapy
Stroke*/drug therapy
Neuroprotective Agents*/therapeutic use
Humans ; Cell- and Tissue-Based Therapy

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Skocz do pozycji: 16.

Tytuł:: Update on Antioxidant Therapy with Edaravone: Expanding Applications in Neurodegenerative Diseases.
Autorzy:: Yamashita T; Department of Neurology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Okayama 700-8558, Japan.
Abe K; Department of Neurology, National Center of Neurology and Psychiatry, Tokyo 187-8551, Japan.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Mar 03; Vol. 25 (5). Date of Electronic Publication: 2024 Mar 03.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Amyotrophic Lateral Sclerosis*/drug therapy
Neurodegenerative Diseases*/drug therapy
Neuroprotective Agents*/pharmacology
Animals ; Female ; Pregnancy ; Antioxidants/therapeutic use ; Antipyrine ; Edaravone/pharmacology ; Edaravone/therapeutic use ; Free Radical Scavengers/pharmacology ; Placenta

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Skocz do pozycji: 17.

Tytuł:: Neuroprotective Effects of Polysaccharides and Gallic Acid from Amauroderma rugosum against 6-OHDA-Induced Toxicity in SH-SY5Y Cells.
Autorzy:: Rangsinth P; Department of Pharmacology and Pharmacy, The University of Hong Kong, Hong Kong SAR, China.
Pattarachotanant N; Department of Clinical Chemistry, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand.
Wang W; Department of Pharmacology and Pharmacy, The University of Hong Kong, Hong Kong SAR, China.
Shiu PH; Department of Pharmacology and Pharmacy, The University of Hong Kong, Hong Kong SAR, China.
Zheng C; Department of Pharmacology and Pharmacy, The University of Hong Kong, Hong Kong SAR, China.
Li R; Department of Pharmacology and Pharmacy, The University of Hong Kong, Hong Kong SAR, China.
Tencomnao T; Department of Clinical Chemistry, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand.
Chuchawankul S; Department of Transfusion Medicine and Clinical Microbiology, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand.
Prasansuklab A; College of Public Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand.
Cheung TM; Tian Ran Healthcare Limited, Hong Kong SAR, China.
Li J; Department of Rehabilitation Sciences, Faculty of Health and Social Sciences, Hong Kong Polytechnic University, Hong Kong SAR, China.
Leung GP; Department of Pharmacology and Pharmacy, The University of Hong Kong, Hong Kong SAR, China.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2024 Feb 22; Vol. 29 (5). Date of Electronic Publication: 2024 Feb 22.
Typ publikacji:: Journal Article
MeSH Terms:: Neuroprotective Agents*/pharmacology
Neuroblastoma*/drug therapy
Parkinson Disease*/drug therapy
Polyporaceae*
Humans ; Oxidopamine/pharmacology ; Antioxidants/pharmacology ; Gallic Acid/pharmacology ; Proto-Oncogene Proteins c-akt/metabolism ; Cell Line, Tumor ; Apoptosis ; Reactive Oxygen Species/metabolism ; TOR Serine-Threonine Kinases ; Mitogen-Activated Protein Kinase Kinases
SCR Organism:: Amauroderma rugosum

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Skocz do pozycji: 18.

Tytuł:: Effect of Diacetylcurcumin Manganese Complex on Rotenone-Induced Oxidative Stress, Mitochondria Dysfunction, and Inflammation in the SH-SY5Y Parkinson's Disease Cell Model.
Autorzy:: Pirunkaset E; Graduate School of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen 40002, Thailand.
Boonyarat C; Division of Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen 40002, Thailand.
Maneenet J; Division of Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen 40002, Thailand.; Natural Drug Discovery Laboratory, Institute of Natural Medicine, University of Toyama, Toyama 930-0154, Japan.
Khamphukdee C; Division of Pharmacognosy and Toxicology, Faculty of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen 40002, Thailand.
Daodee S; Division of Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen 40002, Thailand.
Monthakantirat O; Division of Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen 40002, Thailand.
Awale S; Natural Drug Discovery Laboratory, Institute of Natural Medicine, University of Toyama, Toyama 930-0154, Japan.
Kijjoa A; ICBAS-Instituto de Ciências Biomédicas Abel Salazar and CIIMAR, Universidade do Porto, 4050-313 Porto, Portugal.
Chulikhit Y; Division of Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen 40002, Thailand.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2024 Feb 22; Vol. 29 (5). Date of Electronic Publication: 2024 Feb 22.
Typ publikacji:: Journal Article
MeSH Terms:: Parkinson Disease*
Neuroprotective Agents*/pharmacology
Neuroblastoma*
Neurotoxicity Syndromes*
Mitochondrial Diseases*
Curcumin/*analogs & derivatives
Humans ; Manganese/metabolism ; Reactive Oxygen Species/metabolism ; Rotenone/pharmacology ; Kelch-Like ECH-Associated Protein 1/metabolism ; NF-E2-Related Factor 2/metabolism ; Oxidative Stress ; Inflammation ; Superoxide Dismutase/metabolism ; Antioxidants/pharmacology ; RNA, Messenger/genetics

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Skocz do pozycji: 19.

Tytuł:: Linalool, a Fragrance Compound in Plants, Protects Dopaminergic Neurons and Improves Motor Function and Skeletal Muscle Strength in Experimental Models of Parkinson's Disease.
Autorzy:: Chang WH; Department of Pharmacology, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.
Hsu HT; Department of Anesthesia, Kaohsiung Medical University Chung-Ho Memorial Hospital, Kaohsiung 80756, Taiwan.; Faculty of Anesthesiology, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.
Lin CC; Department of Pharmacology, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.
An LM; Department of Pharmacology, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.
Lee CH; Department of Pharmacology, School of Post-Baccalaureate Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.; Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung 80708, Taiwan.
Ko HH; School of Pharmacy, College of Pharmacy, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.
Lin CL; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.; Division of Neurosurgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung 80756, Taiwan.; Department of Surgery, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.
Lo YC; Department of Pharmacology, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.; Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung 80708, Taiwan.; School of Pharmacy, College of Pharmacy, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.; School of Post-Baccalaureate Medicine, College of Medicine, National Sun Yat-Sen University, Kaohsiung 80424, Taiwan.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Feb 21; Vol. 25 (5). Date of Electronic Publication: 2024 Feb 21.
Typ publikacji:: Journal Article
MeSH Terms:: Parkinson Disease*/metabolism
Neuroprotective Agents*/pharmacology
Neuroblastoma*/metabolism
Acyclic Monoterpenes*
Humans ; Mice ; Animals ; Dopaminergic Neurons/metabolism ; Antioxidants/metabolism ; Odorants ; Sirtuin 1/metabolism ; 1-Methyl-4-phenylpyridinium ; Muscle Strength ; Models, Theoretical ; gamma-Aminobutyric Acid/metabolism

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Skocz do pozycji: 20.

Tytuł:: Siponimod Attenuates Neuronal Cell Death Triggered by Neuroinflammation via NFκB and Mitochondrial Pathways.
Autorzy:: Gurrea-Rubio M; Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109, USA.
Wang Q; Department of Neurology, University of Michigan Medical School, Ann Arbor, MI 48109, USA.; Autoimmunity Center of Excellence, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
Mills EA; Department of Neurology, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
Wu Q; Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109, USA.; Department of Neurology, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
Pitt D; Department of Neurology, Yale Medicine, New Haven, CT 06473, USA.
Tsou PS; Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109, USA.; Autoimmunity Center of Excellence, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
Fox DA; Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109, USA.; Autoimmunity Center of Excellence, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
Mao-Draayer Y; Department of Neurology, University of Michigan Medical School, Ann Arbor, MI 48109, USA.; Autoimmunity Center of Excellence, University of Michigan Medical School, Ann Arbor, MI 48109, USA.; Multiple Sclerosis Center of Excellence, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Feb 20; Vol. 25 (5). Date of Electronic Publication: 2024 Feb 20.
Typ publikacji:: Journal Article
MeSH Terms:: Neuroprotective Agents*/pharmacology
Multiple Sclerosis*/drug therapy
Multiple Sclerosis, Chronic Progressive*/drug therapy
Azetidines*
Benzyl Compounds*
Humans ; Animals ; Rats ; Sphingosine-1-Phosphate Receptors ; Neuroinflammatory Diseases ; Tumor Necrosis Factor-alpha/therapeutic use ; Cell Death

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