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Wyszukujesz frazę ""NF-kappa B"" wg kryterium: Temat


Tytuł:
PAUF Induces Migration of Human Pancreatic Cancer Cells Exclusively via the TLR4/MyD88/NF-κB Signaling Pathway.
Autorzy:
Youn SE; Department of Biomedical Sciences, Dong-A University, Busan 49315, Korea.; Innovative Discovery Center, Prestige BioPharma Korea, Busan 46726, Korea.
Jiang F; Innovative Discovery Center, Prestige BioPharma Korea, Busan 46726, Korea.
Won HY; Innovative Discovery Center, Prestige BioPharma Korea, Busan 46726, Korea.
Hong DE; Department of Biomedical Sciences, Dong-A University, Busan 49315, Korea.; Innovative Discovery Center, Prestige BioPharma Korea, Busan 46726, Korea.
Kang TH; Innovative Discovery Center, Prestige BioPharma Korea, Busan 46726, Korea.
Park YY; Innovative Discovery Center, Prestige BioPharma Korea, Busan 46726, Korea.
Koh SS; Department of Biomedical Sciences, Dong-A University, Busan 49315, Korea.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Sep 27; Vol. 23 (19). Date of Electronic Publication: 2022 Sep 27.
Typ publikacji:
Journal Article
MeSH Terms:
Intercellular Signaling Peptides and Proteins*/genetics
Intercellular Signaling Peptides and Proteins*/metabolism
Myeloid Differentiation Factor 88*/genetics
Myeloid Differentiation Factor 88*/metabolism
NF-kappa B p50 Subunit*/genetics
NF-kappa B p50 Subunit*/metabolism
Pancreatic Neoplasms*/genetics
Pancreatic Neoplasms*/metabolism
Toll-Like Receptor 4*/genetics
Toll-Like Receptor 4*/metabolism
Adaptor Proteins, Vesicular Transport/metabolism ; B7-H1 Antigen/genetics ; B7-H1 Antigen/metabolism ; Cell Movement/genetics ; Cell Movement/physiology ; Humans ; Lectins/metabolism ; NF-kappa B/genetics ; NF-kappa B/metabolism ; Signal Transduction
SCR Disease Name:
Pancreatic Carcinoma
Czasopismo naukowe
Tytuł:
Detrimental NFKB1 missense variants affecting the Rel-homology domain of p105/p50.
Autorzy:
Fliegauf M; Institute for Immunodeficiency (IFI), Center for Chronic Immunodeficiency (CCI), Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; CIBSS - Centre for Integrative Biological Signalling Studies, Freiburg, Germany.
Kinnunen M; Institute of Biotechnology, University of Helsinki, Helsinki, Finland.
Posadas-Cantera S; Institute for Immunodeficiency (IFI), Center for Chronic Immunodeficiency (CCI), Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Camacho-Ordonez N; Institute for Immunodeficiency (IFI), Center for Chronic Immunodeficiency (CCI), Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Faculty of Biology, University of Freiburg, Freiburg, Germany.
Abolhassani H; Department of Biosciences and Nutrition, NEO, Karolinska Institutet, Huddinge, Sweden.; Research Center for Immunodeficiencies, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
Alsina L; Clinical Immunology and Primary Immunodeficiencies Unit, Pediatric Allergy and Clinical Immunology Department, Hospital Sant Joan de Déu, Institut de Recerca Sant Joan de Déu, Barcelona, Spain.; Department of Surgery and Surgical Specializations, Facultat de Medicina i Ciències de la Salut, Barcelona, Spain.
Atschekzei F; RESIST - Cluster of Excellence 2155 to Hanover Medical School , Satellite Center Freiburg, Freiburg, Germany.; Department for Clinical Immunology and Rheumatology, Hannover Medical School, Hanover, Germany.
Bogaert DJ; Department of Pediatrics, Division of Pediatric Hemato-Oncology and Stem Cell Transplantation, Ghent University Hospital, Ghent, Belgium.; Primary Immunodeficiency Research Lab, Center for Primary Immunodeficiency Ghent, Jeffrey Modell Diagnosis and Research Center, Ghent University Hospital, Ghent, Belgium.
Burns SO; Department of Immunology, Royal Free London NHS Foundation Trust, London, United Kingdom.; Institute of Immunity and Transplantation, University College London, London, United Kingdom.
Church JA; Department of Pediatrics, Keck School of Medicine, University of Southern California and Children's Hospital Los Angeles, Los Angeles, CA, United States.
Dückers G; HELIOS Children's Hospital, Krefeld, Germany.
Freeman AF; Laboratory of Clinical Immunology and Microbiology, National Institutes of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, United States.
Hammarström L; Department of Biosciences and Nutrition, NEO, Karolinska Institutet, Huddinge, Sweden.
Hanitsch LG; Department of Medical Immunology, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Kerre T; Department of Hematology, Ghent University Hospital, Ghent, Belgium.
Kobbe R; Institute for Infection Research and Vaccine Development (IIRVD), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Sharapova SO; Research Department, Belarusian Research Center for Pediatric Oncology, Hematology and Immunology, Minsk, Belarus.
Siepermann K; HELIOS Children's Hospital, Krefeld, Germany.
Speckmann C; Institute for Immunodeficiency (IFI), Center for Chronic Immunodeficiency (CCI), Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Center for Pediatrics and Adolescent Medicine, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Steiner S; Department of Medical Immunology, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Verma N; Department of Immunology, Royal Free London NHS Foundation Trust, London, United Kingdom.
Walter JE; Division of Allergy and Immunology, Department of Pediatrics, Morsani College of Medicine, University of South Florida, Tampa, FL, United States.; Division of Allergy/Immunology, Department of Pediatrics Johns Hopkins All Children's Hospital, St. Petersburg, FL, United States.; Division of Allergy and Immunology, Massachusetts General Hospital for Children, Boston, MA, United States.
Westermann-Clark E; Division of Allergy and Immunology, Department of Pediatrics, Morsani College of Medicine, University of South Florida, Tampa, FL, United States.; Division of Allergy and Immunology, Department of Medicine, Morsani College of Medicine, University of South Florida, Tampa, FL, United States.
Goldacker S; Center for Chronic Immunodeficiency (CCI), Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Department of Rheumatology and Clinical Immunology, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Warnatz K; Center for Chronic Immunodeficiency (CCI), Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Department of Rheumatology and Clinical Immunology, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Varjosalo M; Institute of Biotechnology, University of Helsinki, Helsinki, Finland.; Helsinki Institute of Life Science, University of Helsinki, Helsinki, Finland.; Proteomics Unit, University of Helsinki, Helsinki, Finland.
Grimbacher B; Institute for Immunodeficiency (IFI), Center for Chronic Immunodeficiency (CCI), Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; CIBSS - Centre for Integrative Biological Signalling Studies, Freiburg, Germany.; RESIST - Cluster of Excellence 2155 to Hanover Medical School , Satellite Center Freiburg, Freiburg, Germany.; DZIF - German Center for Infection Research, Satellite Center Freiburg, Freiburg, Germany.
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Źródło:
Frontiers in immunology [Front Immunol] 2022 Aug 29; Vol. 13, pp. 965326. Date of Electronic Publication: 2022 Aug 29 (Print Publication: 2022).
Typ publikacji:
Journal Article
MeSH Terms:
Mutation, Missense*
NF-kappa B*/metabolism
DNA ; HEK293 Cells ; Humans ; NF-kappa B p50 Subunit/genetics ; NF-kappa B p50 Subunit/metabolism ; Promoter Regions, Genetic ; Proto-Oncogene Proteins c-rel/metabolism
Czasopismo naukowe
Tytuł:
Genetic variants in the NF-κB signaling pathway (NFKB1, NFKBIA, NFKBIZ) and risk of critical outcome among COVID-19 patients.
Autorzy:
Camblor DG; Genética Molecular, Hospital Universitario Central Asturias, Oviedo, Spain.
Miranda D; Genética Molecular, Hospital Universitario Central Asturias, Oviedo, Spain.
Albaiceta GM; Unidad de Cuidados Intensivos Cardiológicos, Hospital Universitario Central Asturias, Oviedo, Spain; Instituto de Investigación Sanitaria del Principado de Asturias, ISPA, Oviedo, Spain; Universidad de Oviedo, Oviedo, Spain; CIBER-Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain; Instituto Universitario de Oncología del Principado de Asturias, Oviedo, Spain.
Amado-Rodríguez L; Unidad de Cuidados Intensivos Cardiológicos, Hospital Universitario Central Asturias, Oviedo, Spain; Instituto de Investigación Sanitaria del Principado de Asturias, ISPA, Oviedo, Spain; Universidad de Oviedo, Oviedo, Spain; CIBER-Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain; Instituto Universitario de Oncología del Principado de Asturias, Oviedo, Spain.
Cuesta-Llavona E; Genética Molecular, Hospital Universitario Central Asturias, Oviedo, Spain; Instituto de Investigación Sanitaria del Principado de Asturias, ISPA, Oviedo, Spain.
Vázquez-Coto D; Genética Molecular, Hospital Universitario Central Asturias, Oviedo, Spain.
Gómez de Oña J; Servicio de Medicina Intensiva, Hospital de Poniente, El Ejido, Spain.
García-Lago C; Genética Molecular, Hospital Universitario Central Asturias, Oviedo, Spain; Instituto de Investigación Sanitaria del Principado de Asturias, ISPA, Oviedo, Spain.
Gómez J; Genética Molecular, Hospital Universitario Central Asturias, Oviedo, Spain; Instituto de Investigación Sanitaria del Principado de Asturias, ISPA, Oviedo, Spain.
Coto E; Genética Molecular, Hospital Universitario Central Asturias, Oviedo, Spain; Instituto de Investigación Sanitaria del Principado de Asturias, ISPA, Oviedo, Spain; Universidad de Oviedo, Oviedo, Spain. Electronic address: .
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Źródło:
Human immunology [Hum Immunol] 2022 Aug-Sep; Vol. 83 (8-9), pp. 613-617. Date of Electronic Publication: 2022 Jun 21.
Typ publikacji:
Journal Article
MeSH Terms:
COVID-19*/genetics
NF-kappa B*/genetics
Adaptor Proteins, Signal Transducing ; Genetic Association Studies ; Genetic Predisposition to Disease ; Humans ; NF-KappaB Inhibitor alpha/genetics ; NF-kappa B p50 Subunit/genetics ; Polymorphism, Single Nucleotide ; SARS-CoV-2 ; Signal Transduction
Czasopismo naukowe
Tytuł:
The Mechanism of Inflammatory Factors and Soluble Vascular Cell Adhesion Molecule-1 Regulated by Nuclear Transcription Factor NF- κ B in Unstable Angina Pectoris.
Autorzy:
Su Q; Department of Cardiology, Shanxi Provincial People's Hospital, Taiyuan, Shanxi, China.
Zhang L; Department of Cardiology, Shanxi Provincial People's Hospital, Taiyuan, Shanxi, China.
Qi Z; Department of Cardiology, Shanxi Provincial People's Hospital, Taiyuan, Shanxi, China.
Huang B; Laboratory Animal Center, Shanxi Provincial People's Hospital, Taiyuan, Shanxi, China.
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Źródło:
Journal of immunology research [J Immunol Res] 2022 Jul 30; Vol. 2022, pp. 6137219. Date of Electronic Publication: 2022 Jul 30 (Print Publication: 2022).
Typ publikacji:
Journal Article
MeSH Terms:
NF-kappa B*/metabolism
Nicotinamide Phosphoribosyltransferase*/metabolism
Angina, Unstable/metabolism ; C-Reactive Protein/metabolism ; Humans ; Interleukin-17/metabolism ; Interleukin-23/metabolism ; NF-kappa B p52 Subunit ; RNA, Messenger ; Vascular Cell Adhesion Molecule-1/metabolism
Czasopismo naukowe
Tytuł:
The Pro-Inflammatory Deletion Allele of the NF-κB1 Polymorphism Is Characterized by a Depletion of Subunit p50 in Sepsis.
Autorzy:
Marko B; Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie, Universitätsklinikum Knappschaftskrankenhaus Bochum, In der Schornau 23-25, D-44892 Bochum, Germany.
Heurich P; Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie, Universitätsklinikum Knappschaftskrankenhaus Bochum, In der Schornau 23-25, D-44892 Bochum, Germany.
Thon P; Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie, Universitätsklinikum Knappschaftskrankenhaus Bochum, In der Schornau 23-25, D-44892 Bochum, Germany.
Zimmer F; Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie, Universitätsklinikum Knappschaftskrankenhaus Bochum, In der Schornau 23-25, D-44892 Bochum, Germany.
Bergmann L; Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie, Universitätsklinikum Knappschaftskrankenhaus Bochum, In der Schornau 23-25, D-44892 Bochum, Germany.
Nowak H; Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie, Universitätsklinikum Knappschaftskrankenhaus Bochum, In der Schornau 23-25, D-44892 Bochum, Germany.
Rump K; Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie, Universitätsklinikum Knappschaftskrankenhaus Bochum, In der Schornau 23-25, D-44892 Bochum, Germany.
Koos B; Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie, Universitätsklinikum Knappschaftskrankenhaus Bochum, In der Schornau 23-25, D-44892 Bochum, Germany.
Adamzik M; Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie, Universitätsklinikum Knappschaftskrankenhaus Bochum, In der Schornau 23-25, D-44892 Bochum, Germany.
Unterberg M; Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie, Universitätsklinikum Knappschaftskrankenhaus Bochum, In der Schornau 23-25, D-44892 Bochum, Germany.
Rahmel T; Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie, Universitätsklinikum Knappschaftskrankenhaus Bochum, In der Schornau 23-25, D-44892 Bochum, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Jul 08; Vol. 23 (14). Date of Electronic Publication: 2022 Jul 08.
Typ publikacji:
Journal Article
MeSH Terms:
NF-kappa B*/genetics
Sepsis*/genetics
Alleles ; Humans ; Inflammation/genetics ; Leukocytes, Mononuclear ; Lipopolysaccharides ; NF-kappa B p50 Subunit/genetics
Czasopismo naukowe
Tytuł:
NF-κB in control of regulatory T cell development, identity, and function.
Autorzy:
Hövelmeyer N; Institute for Molecular Medicine, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany. .; Germany Research Center for Immunotherapy (FZI), University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany. .
Schmidt-Supprian M; Institute for Experimental Hematology, Center for Translational Cancer Research (TranslaTUM), School of Medicine, Technical University Munich, Munich, Germany. .; German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany. .
Ohnmacht C; Center for Allergy and Environment (ZAUM), Technical University and Helmholtz Center Munich, Munich, Germany. .
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Źródło:
Journal of molecular medicine (Berlin, Germany) [J Mol Med (Berl)] 2022 Jul; Vol. 100 (7), pp. 985-995. Date of Electronic Publication: 2022 Jun 08.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
NF-kappa B*/genetics
T-Lymphocytes, Regulatory*
Animals ; Autoimmunity ; Humans ; Immune Tolerance ; Mice ; NF-kappa B p50 Subunit/metabolism
Czasopismo naukowe
Tytuł:
Trim14 promotes osteoclastogenesis and noncanonical NF-κB activation by targeting p100/p52 in chronic periodontitis.
Autorzy:
Zhang J; Department of Dental Clinic, Cangzhou Central Hospital, Cangzhou, China.
Lin X; Department of Dental Clinic, Cangzhou Central Hospital, Cangzhou, China.
Sun Y; Department of Dental Clinic, Cangzhou Central Hospital, Cangzhou, China.
Wei J; Department of Dental Clinic, Cangzhou Central Hospital, Cangzhou, China.
Wu J; Department of Dental Clinic, Cangzhou Central Hospital, Cangzhou, China.
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Źródło:
Oral diseases [Oral Dis] 2022 Oct; Vol. 28 (7), pp. 1958-1967. Date of Electronic Publication: 2021 May 10.
Typ publikacji:
Journal Article
MeSH Terms:
Chronic Periodontitis*/metabolism
Intracellular Signaling Peptides and Proteins/*metabolism
NF-kappa B p52 Subunit/*metabolism
Tripartite Motif Proteins/*metabolism
Animals ; Mice ; NF-kappa B/metabolism ; Osteoclasts ; Osteogenesis ; RANK Ligand/metabolism ; Signal Transduction
Czasopismo naukowe
Tytuł:
Transcriptional regulation of Acsl1 by CHREBP and NF-kappa B in macrophages during hyperglycemia and inflammation.
Autorzy:
Thevkar-Nagesh P; Department of Microbiology, NYU School of Medicine, New York, NY, United States of America.; Department of Medicine, NYU School of Medicine, New York, NY, United States of America.; Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States of America.
Habault J; Department of Microbiology, NYU School of Medicine, New York, NY, United States of America.
Voisin M; Department of Microbiology, NYU School of Medicine, New York, NY, United States of America.
Ruff SE; Department of Microbiology, NYU School of Medicine, New York, NY, United States of America.
Ha S; Department of Urology, NYU School of Medicine, New York, NY, United States of America.
Ruoff R; Department of Microbiology, NYU School of Medicine, New York, NY, United States of America.
Chen X; Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States of America.; Hosptial for Special Surgery, New York, NY, United States of America.
Rawal S; Department of Medicine, NYU School of Medicine, New York, NY, United States of America.
Zahr T; Department of Medicine, NYU School of Medicine, New York, NY, United States of America.
Szabo G; Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States of America.
Rogatsky I; Hosptial for Special Surgery, New York, NY, United States of America.; Graduate Program in Immunology and Microbial Pathogenesis, Weill Cornell Graduate School for Medical Sciences, New York, NY, United States of America.
Fisher EA; Department of Microbiology, NYU School of Medicine, New York, NY, United States of America.; Department of Medicine, NYU School of Medicine, New York, NY, United States of America.
Garabedian MJ; Department of Microbiology, NYU School of Medicine, New York, NY, United States of America.
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Źródło:
PloS one [PLoS One] 2022 Sep 02; Vol. 17 (9), pp. e0272986. Date of Electronic Publication: 2022 Sep 02 (Print Publication: 2022).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Hyperglycemia*/genetics
Hyperglycemia*/metabolism
NF-kappa B*/metabolism
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors/*metabolism
Coenzyme A Ligases/*genetics
Inflammation/*metabolism
NF-kappa B p50 Subunit/*metabolism
Animals ; Coenzyme A/metabolism ; Glucose/metabolism ; Glucose/pharmacology ; Humans ; Inflammation/genetics ; Lipopolysaccharides/metabolism ; Lipopolysaccharides/pharmacology ; Macrophages/metabolism ; Mice ; RNA, Messenger/genetics
Czasopismo naukowe
Tytuł:
Circular RNA circNFKB1 promotes osteoarthritis progression through interacting with ENO1 and sustaining NF-κB signaling.
Autorzy:
Tang S; Clinical Research Centre, Zhujiang Hospital, Southern Medical University, 510280, Guangzhou, Guangdong, China. .; Centre of Orthopedics, Zhujiang Hospital, Southern Medical University, 510280, Guangzhou, Guangdong, China. .
Nie X; Clinical Research Centre, Zhujiang Hospital, Southern Medical University, 510280, Guangzhou, Guangdong, China.
Ruan J; Clinical Research Centre, Zhujiang Hospital, Southern Medical University, 510280, Guangzhou, Guangdong, China.
Cao Y; Clinical Research Centre, Zhujiang Hospital, Southern Medical University, 510280, Guangzhou, Guangdong, China.; Department of Rheumatology and Immunology, Zhujiang Hospital, Southern Medical University, 510280, Guangzhou, Guangdong, China.
Kang J; Clinical Research Centre, Zhujiang Hospital, Southern Medical University, 510280, Guangzhou, Guangdong, China.
Ding C; Clinical Research Centre, Zhujiang Hospital, Southern Medical University, 510280, Guangzhou, Guangdong, China. .; Menzies Institute for Medical Research, University of Tasmania, 7000, Hobart, Tasmania, Australia. .
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Źródło:
Cell death & disease [Cell Death Dis] 2022 Aug 09; Vol. 13 (8), pp. 695. Date of Electronic Publication: 2022 Aug 09.
Typ publikacji:
Journal Article
MeSH Terms:
Cartilage, Articular*/pathology
Osteoarthritis*/metabolism
NF-kappa B p50 Subunit/*genetics
RNA, Circular/*metabolism
Animals ; Biomarkers, Tumor/metabolism ; Cells, Cultured ; Chondrocytes/metabolism ; DNA-Binding Proteins/metabolism ; Humans ; Interleukin-1beta/genetics ; Interleukin-1beta/metabolism ; Mice ; NF-kappa B/genetics ; NF-kappa B/metabolism ; NF-kappa B p50 Subunit/metabolism ; Phosphopyruvate Hydratase/metabolism ; Signal Transduction ; Tumor Suppressor Proteins/metabolism
Czasopismo naukowe
Tytuł:
Bcl-3: A Double-Edged Sword in Immune Cells and Inflammation.
Autorzy:
Liu H; Henan Key Laboratory of Immunology and Targeted Drug, Henan Collaborative Innovation Center of Molecular Diagnosis and Laboratory Medicine, School of Laboratory Medicine, Xinxiang Medical University, Xinxiang, China.
Zeng L; Henan Key Laboratory of Immunology and Targeted Drug, Henan Collaborative Innovation Center of Molecular Diagnosis and Laboratory Medicine, School of Laboratory Medicine, Xinxiang Medical University, Xinxiang, China.
Yang Y; Department of Translational Medicine Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Guo C; Henan Key Laboratory of Immunology and Targeted Drug, Henan Collaborative Innovation Center of Molecular Diagnosis and Laboratory Medicine, School of Laboratory Medicine, Xinxiang Medical University, Xinxiang, China.
Wang H; Henan Key Laboratory of Immunology and Targeted Drug, Henan Collaborative Innovation Center of Molecular Diagnosis and Laboratory Medicine, School of Laboratory Medicine, Xinxiang Medical University, Xinxiang, China.
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Źródło:
Frontiers in immunology [Front Immunol] 2022 Mar 10; Vol. 13, pp. 847699. Date of Electronic Publication: 2022 Mar 10 (Print Publication: 2022).
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
I-kappa B Proteins*/metabolism
NF-kappa B*/metabolism
Apoptosis ; B-Cell Lymphoma 3 Protein ; Humans ; Inflammation ; NF-kappa B p50 Subunit
Czasopismo naukowe
Tytuł:
Remote ischemic preconditioning causes transient cell cycle arrest and renal protection by a NF-κB-dependent Sema5B pathway.
Autorzy:
Rossaint J; Department of Anesthesiology, Intensive Care and Pain Medicine, University Hospital Münster, Münster, Germany.
Meersch M; Department of Anesthesiology, Intensive Care and Pain Medicine, University Hospital Münster, Münster, Germany.
Thomas K; Department of Anesthesiology, Intensive Care and Pain Medicine, University Hospital Münster, Münster, Germany.
Mersmann S; Department of Anesthesiology, Intensive Care and Pain Medicine, University Hospital Münster, Münster, Germany.
Lehmann M; Department of Anesthesiology, Intensive Care and Pain Medicine, University Hospital Münster, Münster, Germany.
Skupski J; Department of Anesthesiology, Intensive Care and Pain Medicine, University Hospital Münster, Münster, Germany.
Tekath T; Institute of Medical Informatics, University of Münster, Münster, Germany.
Rosenberger P; Department of Anesthesiology and Intensive Care Medicine, University Hospital Tübingen, Eberhard Karls University Tübingen, Tübingen, Germany.
Kellum JA; The Center for Critical Care Nephrology, Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Pavenstädt H; Department of Nephrology, Internal Medicine D, University Hospital Münster, Münster, Germany.
Zarbock A; Department of Anesthesiology, Intensive Care and Pain Medicine, University Hospital Münster, Münster, Germany.
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Źródło:
JCI insight [JCI Insight] 2022 Jul 22; Vol. 7 (14). Date of Electronic Publication: 2022 Jul 22.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Acute Kidney Injury*/metabolism
Acute Kidney Injury*/prevention & control
HMGB1 Protein*/genetics
HMGB1 Protein*/metabolism
Ischemic Preconditioning*/methods
NF-kappa B p50 Subunit/*metabolism
Animals ; Cell Cycle Checkpoints ; Kidney/metabolism ; Mice ; NF-kappa B/metabolism ; Toll-Like Receptor 4/metabolism
Czasopismo naukowe
Tytuł:
Changes in expression of nuclear factor kappa B subunits in the ovine thymus during early pregnancy.
Autorzy:
Yang L; School of Life Sciences and Food Engineering, Hebei University of Engineering, Handan, 056038, China. .
Cai C; School of Life Sciences and Food Engineering, Hebei University of Engineering, Handan, 056038, China.
Fang S; School of Life Sciences and Food Engineering, Hebei University of Engineering, Handan, 056038, China.
Hao S; School of Life Sciences and Food Engineering, Hebei University of Engineering, Handan, 056038, China.
Zhang T; School of Life Sciences and Food Engineering, Hebei University of Engineering, Handan, 056038, China.
Zhang L; School of Life Sciences and Food Engineering, Hebei University of Engineering, Handan, 056038, China.
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Źródło:
Scientific reports [Sci Rep] 2022 Oct 21; Vol. 12 (1), pp. 17683. Date of Electronic Publication: 2022 Oct 21.
Typ publikacji:
Journal Article
MeSH Terms:
NF-kappa B*/metabolism
NF-kappa B p52 Subunit*/metabolism
Sheep/genetics ; Animals ; Female ; Pregnancy ; Thymus Gland/metabolism ; RNA, Messenger
Czasopismo naukowe
Tytuł:
A familial case of B-cell expansion with NF-κB and T-cell anergy caused by a G123D heterozygous missense mutation in the CARD11 gene.
Autorzy:
Takase Y; Department of Pediatrics, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan.
Tanioka S; Department of Pediatrics, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan.
Ishimura M; Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Yoshiura KI; Department of Human Genetics, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan.
Mori Y; Department of Medicine and Biosystemic Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Sakaida E; Department of Endocrinology, Hematology and Gerontology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Funakoshi Y; Department of Pediatrics, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan.
Moriuchi H; Department of Pediatrics, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan.
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Źródło:
Pediatric blood & cancer [Pediatr Blood Cancer] 2022 Dec; Vol. 69 (12), pp. e29941. Date of Electronic Publication: 2022 Sep 21.
Typ publikacji:
Journal Article
MeSH Terms:
NF-kappa B*/genetics
NF-kappa B*/metabolism
Immunologic Deficiency Syndromes*
Child ; Female ; Male ; Humans ; Young Adult ; Adult ; CARD Signaling Adaptor Proteins/genetics ; CARD Signaling Adaptor Proteins/metabolism ; Guanylate Cyclase/genetics ; Guanylate Cyclase/metabolism ; Mutation, Missense ; B-Lymphocytes/metabolism ; Mutation ; T-Lymphocytes/metabolism
Czasopismo naukowe
Tytuł:
TREM2 Is a Prognostic Biomarker and Correlated with an Immunosuppressive Microenvironment in Thyroid Cancer.
Autorzy:
Wang J; Department of Head and Neck Surgery, Cancer Hospital of China Medical University, NO.44 Xiaoheyan Road, Dadong District, Shenyang 110042, Liaoning Province, China.
Li Z; Department of Head and Neck Surgery, Cancer Hospital of China Medical University, NO.44 Xiaoheyan Road, Dadong District, Shenyang 110042, Liaoning Province, China.
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Źródło:
Disease markers [Dis Markers] 2022 Nov 16; Vol. 2022, pp. 1807386. Date of Electronic Publication: 2022 Nov 16 (Print Publication: 2022).
Typ publikacji:
Journal Article
MeSH Terms:
NF-kappa B*/genetics
NF-kappa B*/metabolism
Thyroid Neoplasms*/diagnosis
Humans ; Prognosis ; Gene Expression Regulation, Neoplastic ; Biomarkers, Tumor/genetics ; Thyroid Cancer, Papillary/diagnosis ; Tumor Microenvironment/genetics ; Membrane Glycoproteins/genetics ; Membrane Glycoproteins/metabolism ; Receptors, Immunologic/genetics ; Receptors, Immunologic/metabolism
Czasopismo naukowe
Tytuł:
Senegalia macrostachya seed polysaccharides attenuate inflammation-induced intestinal epithelial barrier dysfunction in a Caco-2 and RAW264.7 macrophage co-culture model by inhibiting the NF-κB/MLCK pathway.
Autorzy:
Zongo AW; College of Food Science and Technology, Huazhong Agricultural University, Wuhan, 430070, China. .; Key Laboratory of Environment Correlative Dietology (Huazhong Agricultural University), Ministry of Education, China.; Center for Research in Biological Sciences, Food and Nutrition, Department of Biochemistry and Microbiology, University Joseph Ki-Zerbo, BP 7021 Ouagadougou 03, Burkina Faso.
Zogona D; College of Food Science and Technology, Huazhong Agricultural University, Wuhan, 430070, China. .; Key Laboratory of Environment Correlative Dietology (Huazhong Agricultural University), Ministry of Education, China.; Center for Research in Biological Sciences, Food and Nutrition, Department of Biochemistry and Microbiology, University Joseph Ki-Zerbo, BP 7021 Ouagadougou 03, Burkina Faso.
Youssef M; Food Science and Technology Department, Faculty of Agriculture, Al-Azhar University, Cairo, Egypt.
Ye S; College of Food Science and Technology, Huazhong Agricultural University, Wuhan, 430070, China. .; Key Laboratory of Environment Correlative Dietology (Huazhong Agricultural University), Ministry of Education, China.
Zhan F; College of Food Science and Technology, Huazhong Agricultural University, Wuhan, 430070, China. .; Key Laboratory of Environment Correlative Dietology (Huazhong Agricultural University), Ministry of Education, China.
Li J; College of Food Science and Technology, Huazhong Agricultural University, Wuhan, 430070, China. .; Key Laboratory of Environment Correlative Dietology (Huazhong Agricultural University), Ministry of Education, China.
Li B; College of Food Science and Technology, Huazhong Agricultural University, Wuhan, 430070, China. .; Key Laboratory of Environment Correlative Dietology (Huazhong Agricultural University), Ministry of Education, China.
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Źródło:
Food & function [Food Funct] 2022 Nov 14; Vol. 13 (22), pp. 11676-11689. Date of Electronic Publication: 2022 Nov 14.
Typ publikacji:
Journal Article
MeSH Terms:
Myosin Light Chains*/metabolism
NF-kappa B*/genetics
NF-kappa B*/metabolism
Humans ; Caco-2 Cells ; Lipopolysaccharides/pharmacology ; Coculture Techniques ; Intestinal Mucosa/metabolism ; Tight Junctions ; Tumor Necrosis Factor-alpha/metabolism ; Polysaccharides/pharmacology ; Polysaccharides/metabolism ; Inflammation/drug therapy ; Inflammation/metabolism ; Macrophages/metabolism ; RNA, Messenger/metabolism
Czasopismo naukowe
Tytuł:
A computational approach to investigate constitutive activation of NF-κB.
Autorzy:
Mobeen A; CSIR - Institute of Genomics & Integrative Biology, Sukhdev Vihar, New Delhi, India.; Academy of Scientific & Innovative Research (AcSIR), Ghaziabad, Uttar Pradesh, India.
Puniya BL; Department of Biochemistry, University of Nebraska-Lincoln, Lincoln, Nebraska, USA.
Ramachandran S; CSIR - Institute of Genomics & Integrative Biology, Sukhdev Vihar, New Delhi, India.; Academy of Scientific & Innovative Research (AcSIR), Ghaziabad, Uttar Pradesh, India.
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Źródło:
Proteins [Proteins] 2022 Nov; Vol. 90 (11), pp. 1944-1964. Date of Electronic Publication: 2022 Jun 16.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
I-kappa B Kinase*/genetics
I-kappa B Kinase*/metabolism
NF-kappa B*/genetics
NF-kappa B*/metabolism
Cytokines ; PPAR gamma ; Signal Transduction
Czasopismo naukowe
Tytuł:
The Deubiquitinating Enzyme USP4 Functions as an Oncoprotein in Gastric Cancer and Mediates NF-κB Signaling by Regulating PRL-3 Expression.
Autorzy:
Tao Y; Department of Nursing Management, The First Affiliated Hospital of Soochow University, 215006 Suzhou, Jiangsu, China.
You W; Department of Gastroenterology, The First Affiliated Hospital of Soochow University, 215006 Suzhou, Jiangsu, China.
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Źródło:
Frontiers in bioscience (Landmark edition) [Front Biosci (Landmark Ed)] 2022 Oct 19; Vol. 27 (10), pp. 286.
Typ publikacji:
Journal Article
MeSH Terms:
NF-kappa B*/genetics
NF-kappa B*/metabolism
Stomach Neoplasms*/pathology
Humans ; Cell Line, Tumor ; Oncogene Proteins ; Deubiquitinating Enzymes ; Cell Proliferation/genetics ; Ubiquitin-Specific Proteases/genetics
Czasopismo naukowe
Tytuł:
Role and Mechanism of Theaflavins in Regulating Skeletal Muscle Inflammation.
Autorzy:
Liu C; Key Laboratory of Tea Science of Ministry of Education, Hunan Agricultural University, Changsha 410128, Hunan, China.; National Research Center of Engineering Technology for Utilization of Functional Ingredients from Botanicals, Collaborative Innovation Centre of Utilisation of Functional Ingredients from Botanicals and Co-Innovation Center of Education Ministry for Utilization of Botanical Functional Ingredients, Hunan Agricultural University, Changsha 410128, Hunan, China.; Key Laboratory for Evaluation and Utilization of Gene Resources of Horticultural Crops, Ministry of Agriculture and Rural Affairs of China, Hunan Agricultrual University, Changsha 410128, China.
Liu A; College of Bioscience and Biotechnology, Hunan Agricultural University, Changsha 410128, Hunan, China.
Zhou J; Key Laboratory of Tea Science of Ministry of Education, Hunan Agricultural University, Changsha 410128, Hunan, China.; National Research Center of Engineering Technology for Utilization of Functional Ingredients from Botanicals, Collaborative Innovation Centre of Utilisation of Functional Ingredients from Botanicals and Co-Innovation Center of Education Ministry for Utilization of Botanical Functional Ingredients, Hunan Agricultural University, Changsha 410128, Hunan, China.
Zhang Y; Key Laboratory of Tea Science of Ministry of Education, Hunan Agricultural University, Changsha 410128, Hunan, China.; National Research Center of Engineering Technology for Utilization of Functional Ingredients from Botanicals, Collaborative Innovation Centre of Utilisation of Functional Ingredients from Botanicals and Co-Innovation Center of Education Ministry for Utilization of Botanical Functional Ingredients, Hunan Agricultural University, Changsha 410128, Hunan, China.
Zhou F; Key Laboratory of Tea Science of Ministry of Education, Hunan Agricultural University, Changsha 410128, Hunan, China.; National Research Center of Engineering Technology for Utilization of Functional Ingredients from Botanicals, Collaborative Innovation Centre of Utilisation of Functional Ingredients from Botanicals and Co-Innovation Center of Education Ministry for Utilization of Botanical Functional Ingredients, Hunan Agricultural University, Changsha 410128, Hunan, China.
Chen H; Key Laboratory of Tea Science of Ministry of Education, Hunan Agricultural University, Changsha 410128, Hunan, China.; National Research Center of Engineering Technology for Utilization of Functional Ingredients from Botanicals, Collaborative Innovation Centre of Utilisation of Functional Ingredients from Botanicals and Co-Innovation Center of Education Ministry for Utilization of Botanical Functional Ingredients, Hunan Agricultural University, Changsha 410128, Hunan, China.
Liu Q; Key Laboratory of Tea Science of Ministry of Education, Hunan Agricultural University, Changsha 410128, Hunan, China.; National Research Center of Engineering Technology for Utilization of Functional Ingredients from Botanicals, Collaborative Innovation Centre of Utilisation of Functional Ingredients from Botanicals and Co-Innovation Center of Education Ministry for Utilization of Botanical Functional Ingredients, Hunan Agricultural University, Changsha 410128, Hunan, China.
Zhang S; Key Laboratory of Tea Science of Ministry of Education, Hunan Agricultural University, Changsha 410128, Hunan, China.; National Research Center of Engineering Technology for Utilization of Functional Ingredients from Botanicals, Collaborative Innovation Centre of Utilisation of Functional Ingredients from Botanicals and Co-Innovation Center of Education Ministry for Utilization of Botanical Functional Ingredients, Hunan Agricultural University, Changsha 410128, Hunan, China.
Huang J; Key Laboratory of Tea Science of Ministry of Education, Hunan Agricultural University, Changsha 410128, Hunan, China.; National Research Center of Engineering Technology for Utilization of Functional Ingredients from Botanicals, Collaborative Innovation Centre of Utilisation of Functional Ingredients from Botanicals and Co-Innovation Center of Education Ministry for Utilization of Botanical Functional Ingredients, Hunan Agricultural University, Changsha 410128, Hunan, China.; Key Laboratory for Evaluation and Utilization of Gene Resources of Horticultural Crops, Ministry of Agriculture and Rural Affairs of China, Hunan Agricultrual University, Changsha 410128, China.
Liu Z; Key Laboratory of Tea Science of Ministry of Education, Hunan Agricultural University, Changsha 410128, Hunan, China.; National Research Center of Engineering Technology for Utilization of Functional Ingredients from Botanicals, Collaborative Innovation Centre of Utilisation of Functional Ingredients from Botanicals and Co-Innovation Center of Education Ministry for Utilization of Botanical Functional Ingredients, Hunan Agricultural University, Changsha 410128, Hunan, China.; Key Laboratory for Evaluation and Utilization of Gene Resources of Horticultural Crops, Ministry of Agriculture and Rural Affairs of China, Hunan Agricultrual University, Changsha 410128, China.
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Źródło:
Journal of agricultural and food chemistry [J Agric Food Chem] 2022 Oct 19; Vol. 70 (41), pp. 13233-13250. Date of Electronic Publication: 2022 Oct 10.
Typ publikacji:
Journal Article
MeSH Terms:
NF-kappa B*/genetics
NF-kappa B*/metabolism
Myeloid Differentiation Factor 88*/metabolism
Humans ; Toll-Like Receptor 4/genetics ; Toll-Like Receptor 4/metabolism ; Tumor Necrosis Factor-alpha/metabolism ; Interleukin-6/genetics ; Interleukin-6/metabolism ; Inflammation/drug therapy ; Inflammation/metabolism ; Muscle, Skeletal/metabolism ; Anti-Inflammatory Agents/therapeutic use ; Tea
Czasopismo naukowe
Tytuł:
Sphingosine 1-phosphate receptor 2 mediated early stages of pancreatic and systemic inflammatory responses via NF-kappa B activation in acute pancreatitis.
Autorzy:
Yang J; School of Life Sciences and Health Engineering, Jiangnan University, Wuxi, Jiangsu, China. .
Tang X; School of Life Sciences and Health Engineering, Jiangnan University, Wuxi, Jiangsu, China.
Li B; Department of Critical Care Medicine, Jinling Hospital, Nanjing University School of Medicine, Nanjing, Jiangsu, China.
Shi J; School of Life Sciences and Health Engineering, Jiangnan University, Wuxi, Jiangsu, China. .
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Źródło:
Cell communication and signaling : CCS [Cell Commun Signal] 2022 Oct 13; Vol. 20 (1), pp. 157. Date of Electronic Publication: 2022 Oct 13.
Typ publikacji:
Journal Article; Video-Audio Media; Research Support, Non-U.S. Gov't
MeSH Terms:
NF-kappa B*/metabolism
Pancreatitis*/metabolism
Pancreatitis*/pathology
Sphingosine-1-Phosphate Receptors/*metabolism
Acute Disease ; Animals ; Inflammation/metabolism ; Mice ; Pancreas/metabolism ; Trypsinogen/metabolism ; p38 Mitogen-Activated Protein Kinases
Czasopismo naukowe
Tytuł:
Synthesis and Anti-Inflammatory Activity of 2-Amino-4,5,6,7-tetrahydrobenzo[b]thiophene-Derived NRF2 Activators.
Autorzy:
Mak KK; Pharmaceutical Chemistry Department, International Medical University, 126 Jalan Jalil Perkasa 19, Bukit Jalil, 57000, Kuala Lumpur, Malaysia.; Centre of Excellence for Bioactive Molecules and Drug Delivery, Institute for Research, Development, and Innovation (IRDI), International Medical University, 126 Jalan Jalil Perkasa 19 Bukit Jalil, 57000, Kuala Lumpur, Malaysia.; School of Postgraduate Studies, International Medical University, 126 Jalan Jalil Perkasa 19 Bukit Jalil, 57000, Kuala Lumpur, Malaysia.
Shiming Z; School of Postgraduate Studies, International Medical University, 126 Jalan Jalil Perkasa 19 Bukit Jalil, 57000, Kuala Lumpur, Malaysia.
Epemolu O; Principal research scientist- in vitro/in vivo DMPK, Charles River Laboratories Edinburgh Ltd, Tranent, East Lothian, Scotland, UK.
Dinkova-Kostova AT; School of Medicine, Jacqui Wood Cancer Centre, University of Dundee, Dundee, Scotland, UK.; Departments of Medicine and Pharmacology and Molecular Sciences, Johns Hopkins University, Baltimore, MA, USA.
Wells G; UCL School of Pharmacy, University College London, London, WC1N 1AX, UK.
Gazaryan IG; Faculty of Biology and Biotechnology, National Research University Higher School of Economics, Moscow, Russia.; Department of Chemical Enzymology, M.V. Lomonosov Moscow State University, Moscow, Russia.; Department of Chemistry and Physical Sciences, Pace University, Pleasantville, NY, USA.
Sakirolla R; Department of Chemistry, Central University of Karnataka, Gulbarga, Karnataka, India.
Mohd Z; Pharmaceutical Chemistry Department, International Medical University, 126 Jalan Jalil Perkasa 19, Bukit Jalil, 57000, Kuala Lumpur, Malaysia.; Centre of Excellence for Bioactive Molecules and Drug Delivery, Institute for Research, Development, and Innovation (IRDI), International Medical University, 126 Jalan Jalil Perkasa 19 Bukit Jalil, 57000, Kuala Lumpur, Malaysia.
Pichika MR; Pharmaceutical Chemistry Department, International Medical University, 126 Jalan Jalil Perkasa 19, Bukit Jalil, 57000, Kuala Lumpur, Malaysia.; Centre of Excellence for Bioactive Molecules and Drug Delivery, Institute for Research, Development, and Innovation (IRDI), International Medical University, 126 Jalan Jalil Perkasa 19 Bukit Jalil, 57000, Kuala Lumpur, Malaysia.
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Źródło:
ChemistryOpen [ChemistryOpen] 2022 Oct; Vol. 11 (10), pp. e202200181.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
NF-E2-Related Factor 2*/genetics
NF-E2-Related Factor 2*/metabolism
NF-kappa B*/genetics
NF-kappa B*/metabolism
Mice ; Rats ; Humans ; Animals ; Kelch-Like ECH-Associated Protein 1/genetics ; Kelch-Like ECH-Associated Protein 1/metabolism ; Lipopolysaccharides/pharmacology ; Cyclooxygenase 2/genetics ; Cyclooxygenase 2/metabolism ; Tumor Necrosis Factor-alpha/metabolism ; Thiophenes/pharmacology ; Dinoprostone ; Interleukin-6/metabolism ; Anti-Inflammatory Agents/pharmacology ; Cytokines/metabolism ; Inflammation Mediators ; RNA, Messenger
Czasopismo naukowe

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