APOE ɛ4, but not polygenic Alzheimer's disease risk, is related to longitudinal decrease in hippocampal brain activity in non-demented individuals.
Autorzy:
Håglin S; Department of Integrative Medical Biology, Umeå University, 901 87, Umeå, Sweden.; Umeå Center for Functional Brain Imaging, Umeå University, Umeå, Sweden.; Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden. Koch E; Department of Integrative Medical Biology, Umeå University, 901 87, Umeå, Sweden.; Umeå Center for Functional Brain Imaging, Umeå University, Umeå, Sweden.; Division of Mental Health and Addiction, NORMENT, Centre for Mental Disorders Research, Institute of Clinical Medicine, Oslo University Hospital, University of Oslo, Oslo, Norway. Schäfer Hackenhaar F; Department of Integrative Medical Biology, Umeå University, 901 87, Umeå, Sweden.; Umeå Center for Functional Brain Imaging, Umeå University, Umeå, Sweden. NybergL; Department of Integrative Medical Biology, Umeå University, 901 87, Umeå, Sweden.; Umeå Center for Functional Brain Imaging, Umeå University, Umeå, Sweden.; Department of Radiation Sciences, Diagnostic Radiology, University Hospital, Umeå University, Umeå, Sweden. Kauppi K; Department of Integrative Medical Biology, Umeå University, 901 87, Umeå, Sweden. .; Umeå Center for Functional Brain Imaging, Umeå University, Umeå, Sweden. .; Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Solna, Sweden. .
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Scientific reports [Sci Rep] 2023 May 24; Vol. 13 (1), pp. 8433. Date of Electronic Publication: 2023 May 24.
Longitudinal stability in working memory and frontal activity in relation to general brain maintenance.
Autorzy:
NybergL; Department of Radiation Sciences, Umeå University, 90187, Umeå, Sweden. Lars.Nyberg@umu.se.; Department of Integrative Medical Biology, Umeå University, 90187, Umeå, Sweden. Lars.Nyberg@umu.se.; Umeå Center for Functional Brain Imaging (UFBI), Umeå University, Umeå, Sweden. Lars.Nyberg@umu.se. Karalija N; Department of Integrative Medical Biology, Umeå University, 90187, Umeå, Sweden.; Umeå Center for Functional Brain Imaging (UFBI), Umeå University, Umeå, Sweden. Papenberg G; Aging Research Center, Karolinska Institutet & Stockholm University, Tomtebodavägen 18A, 17165, Stockholm, Sweden. Salami A; Department of Integrative Medical Biology, Umeå University, 90187, Umeå, Sweden.; Umeå Center for Functional Brain Imaging (UFBI), Umeå University, Umeå, Sweden.; Aging Research Center, Karolinska Institutet & Stockholm University, Tomtebodavägen 18A, 17165, Stockholm, Sweden. Andersson M; Department of Integrative Medical Biology, Umeå University, 90187, Umeå, Sweden.; Umeå Center for Functional Brain Imaging (UFBI), Umeå University, Umeå, Sweden. Pedersen R; Department of Integrative Medical Biology, Umeå University, 90187, Umeå, Sweden.; Umeå Center for Functional Brain Imaging (UFBI), Umeå University, Umeå, Sweden. Vikner T; Department of Radiation Sciences, Umeå University, 90187, Umeå, Sweden.; Umeå Center for Functional Brain Imaging (UFBI), Umeå University, Umeå, Sweden. Garrett DD; Center for Lifespan Psychology, Max Planck Institute for Human Development, Lentzeallee 94, 14195, Berlin, Germany.; Max Planck, UCL Centre for Computational Psychiatry and Ageing Research, Lentzeallee 94, 14195, Berlin, Germany. Riklund K; Department of Radiation Sciences, Umeå University, 90187, Umeå, Sweden.; Umeå Center for Functional Brain Imaging (UFBI), Umeå University, Umeå, Sweden. Wåhlin A; Department of Radiation Sciences, Umeå University, 90187, Umeå, Sweden.; Umeå Center for Functional Brain Imaging (UFBI), Umeå University, Umeå, Sweden.; Department of Applied Physics and Electronics, Umeå University, 90187, Umeå, Sweden. Lövdén M; Department of Psychology, University of Gothenburg, Gothenburg, Sweden. Lindenberger U; Center for Lifespan Psychology, Max Planck Institute for Human Development, Lentzeallee 94, 14195, Berlin, Germany.; Max Planck, UCL Centre for Computational Psychiatry and Ageing Research, Lentzeallee 94, 14195, Berlin, Germany. Bäckman L; Aging Research Center, Karolinska Institutet & Stockholm University, Tomtebodavägen 18A, 17165, Stockholm, Sweden.
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Scientific reports [Sci Rep] 2022 Dec 05; Vol. 12 (1), pp. 20957. Date of Electronic Publication: 2022 Dec 05.
Brain aging differs with cognitive ability regardless of education.
Autorzy:
Walhovd KB; Center for Lifespan Changes in Brain and Cognition, University of Oslo, Blindern, POB1094, 0317, Oslo, Norway. .; Department of Radiology and Nuclear Medicine, Oslo University Hospital, Oslo, Norway. . NybergL; Center for Lifespan Changes in Brain and Cognition, University of Oslo, Blindern, POB1094, 0317, Oslo, Norway.; Umeå Center for Functional Brain Imaging, Umeå University, Umeå, Sweden. Lindenberger U; Center for Lifespan Psychology, Max Planck Institute for Human Development, Berlin, Germany.; Max Planck UCL Centre for Computational Psychiatry and Ageing Research, Berlin, Germany.; Max Planck UCL Centre for Computational Psychiatry and Ageing Research, London, UK. Amlien IK; Center for Lifespan Changes in Brain and Cognition, University of Oslo, Blindern, POB1094, 0317, Oslo, Norway. Sørensen Ø; Center for Lifespan Changes in Brain and Cognition, University of Oslo, Blindern, POB1094, 0317, Oslo, Norway. Wang Y; Center for Lifespan Changes in Brain and Cognition, University of Oslo, Blindern, POB1094, 0317, Oslo, Norway. Mowinckel AM; Center for Lifespan Changes in Brain and Cognition, University of Oslo, Blindern, POB1094, 0317, Oslo, Norway. Kievit RA; Cognitive Neuroscience Department, Donders Institute for Brain, Cognition and Behavior, The Netherlands, Radboud University Medical Center, Nijmegen, The Netherlands. Ebmeier KP; Department of Psychiatry, University of Oxford, Oxford, UK. Bartrés-Faz D; Department of Medicine, Faculty of Medicine and Health Sciences & Institute of Neurosciences, Universitat de Barcelona, and Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain. Kühn S; Center for Lifespan Psychology, Max Planck Institute for Human Development, Berlin, Germany.; Clinic and Policlinic for Psychiatry and Psychotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. Boraxbekk CJ; Umeå Center for Functional Brain Imaging, Umeå University, Umeå, Sweden.; Danish Research Centre for Magnetic Resonance (DRCMR), Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital - Amager and Hvidovre, Copenhagen, Denmark.; Department of Radiation Sciences, Diagnostic Radiology, Umeå University, Umeå, Sweden.; Institute of Sports Medicine Copenhagen (ISMC) and Department of Neurology, Copenhagen University Hospital Bispebjerg, Copenhagen, Denmark.; Institute for Clinical Medicine, Faculty of Medical and Health Sciences, University of Copenhagen, Copenhagen, Denmark. Ghisletta P; Faculty of Psychology and Educational Sciences, University of Geneva, Geneva, Switzerland.; UniDistance Suisse, Brig, Switzerland.; Swiss National Centre of Competence in Research LIVES, University of Geneva, Geneva, Switzerland. Madsen KS; Danish Research Centre for Magnetic Resonance (DRCMR), Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital - Amager and Hvidovre, Copenhagen, Denmark.; Radiography, Department of Technology, University College Copenhagen, Copenhagen, Denmark. Baaré WFC; Danish Research Centre for Magnetic Resonance (DRCMR), Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital - Amager and Hvidovre, Copenhagen, Denmark. Zsoldos E; Department of Psychiatry, University of Oxford, Oxford, UK.; Welcome Centre for Integrative Neuroimaging, University of Oxford, Oxford, UK. Magnussen F; Center for Lifespan Changes in Brain and Cognition, University of Oslo, Blindern, POB1094, 0317, Oslo, Norway. Vidal-Piñeiro D; Center for Lifespan Changes in Brain and Cognition, University of Oslo, Blindern, POB1094, 0317, Oslo, Norway. Penninx B; Amsterdam Neuroscience, Department of Psychiatry, Amsterdam UMC, Vrije Universiteit, Amsterdam, The Netherlands. Fjell AM; Center for Lifespan Changes in Brain and Cognition, University of Oslo, Blindern, POB1094, 0317, Oslo, Norway.; Department of Radiology and Nuclear Medicine, Oslo University Hospital, Oslo, Norway.
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Scientific reports [Sci Rep] 2022 Aug 16; Vol. 12 (1), pp. 13886. Date of Electronic Publication: 2022 Aug 16.
Fronto-striatal dopamine D2 receptor availability is associated with cognitive variability in older individuals with low dopamine integrity.
Autorzy:
Korkki SM; Aging Research Center, Karolinska Institute and Stockholm University, Stockholm, Sweden. . Papenberg G; Aging Research Center, Karolinska Institute and Stockholm University, Stockholm, Sweden. Karalija N; Department of Radiation Sciences, Diagnostic Radiology, Umeå University, Umeå, Sweden.; Umeå Center for Functional Brain Imaging, Umeå University, Umeå, Sweden. Garrett DD; Center for Lifespan Psychology, Max Planck Institute for Human Development, Berlin, Germany.; Max Planck UCL Centre for Computational Psychiatry and Ageing Research, Berlin, Germany. Riklund K; Department of Radiation Sciences, Diagnostic Radiology, Umeå University, Umeå, Sweden.; Umeå Center for Functional Brain Imaging, Umeå University, Umeå, Sweden. Lövdén M; Department of Psychology, University of Gothenburg, Gothenburg, Sweden. Lindenberger U; Center for Lifespan Psychology, Max Planck Institute for Human Development, Berlin, Germany.; Max Planck UCL Centre for Computational Psychiatry and Ageing Research, Berlin, Germany. NybergL; Department of Radiation Sciences, Diagnostic Radiology, Umeå University, Umeå, Sweden.; Umeå Center for Functional Brain Imaging, Umeå University, Umeå, Sweden.; Department of Integrative Medical Biology, Umeå University, Umeå, Sweden. Bäckman L; Aging Research Center, Karolinska Institute and Stockholm University, Stockholm, Sweden.
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Scientific reports [Sci Rep] 2021 Oct 26; Vol. 11 (1), pp. 21089. Date of Electronic Publication: 2021 Oct 26.
Typ publikacji:
Clinical Trial; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
Wide temporal horns are associated with cognitive dysfunction, as well as impaired gait and incontinence.
Autorzy:
Lilja-Lund O; Department of Clinical Science, Neuroscience, Umeå University, Östersunds sjukhus, 831 83, Östersund, Sweden. . Kockum K; Department of Clinical Science, Neuroscience, Umeå University, Östersunds sjukhus, 831 83, Östersund, Sweden. Hellström P; Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden. Söderström L; Unit of Research, Education and Development, Östersund Hospital, Region Jämtland Härjedalen, Östersund, Sweden. NybergL; Department of Radiation Sciences, Umeå University, Umeå, Sweden. Laurell K; Department of Neuroscience, Uppsala University, Uppsala, Sweden.
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Źródło:
Scientific reports [Sci Rep] 2020 Oct 23; Vol. 10 (1), pp. 18203. Date of Electronic Publication: 2020 Oct 23.
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