- Title:
- Small-molecule inhibition of PTPRZ reduces tumor growth in a rat model of glioblastoma.
- Authors:
- Source:
- Scientific reports [Sci Rep] 2016 Feb 09; Vol. 6, pp. 20473. Date of Electronic Publication: 2016 Feb 09.
- Publication Type:
- Journal Article; Research Support, Non-U.S. Gov't
- MeSH Terms:
-
Enzyme Inhibitors*/chemistry
Enzyme Inhibitors*/pharmacology
Glioblastoma*/drug therapy
Glioblastoma*/enzymology
Glioblastoma*/genetics
Molecular Docking Simulation*
Neoplasm Proteins*/antagonists & inhibitors
Neoplasm Proteins*/chemistry
Neoplasm Proteins*/genetics
Neoplasm Proteins*/metabolism
Neoplasms, Experimental*/drug therapy
Neoplasms, Experimental*/enzymology
Neoplasms, Experimental*/genetics
Receptor-Like Protein Tyrosine Phosphatases, Class 5*/antagonists & inhibitors
Receptor-Like Protein Tyrosine Phosphatases, Class 5*/chemistry
Receptor-Like Protein Tyrosine Phosphatases, Class 5*/genetics
Receptor-Like Protein Tyrosine Phosphatases, Class 5*/metabolism
Animals ; Cell Line, Tumor ; Crystallography, X-Ray ; Male ; Mutagenesis, Site-Directed ; Rats ; Rats, Wistar
Academic Journal