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Tytuł:
Generation of novel complete HLA class I monoallelic cell lines used in an MHC stabilization assay for neoantigen evaluation.
Autorzy:
Iizuka A; Immunotherapy Division, Shizuoka Cancer Center Research Institute, Shizuoka 411-8777, Japan.
Akiyama Y; Immunotherapy Division, Shizuoka Cancer Center Research Institute, Shizuoka 411-8777, Japan.
Sakura N; Medical Genetics Division, Shizuoka Cancer Center Research Institute, Shizuoka 411-8777, Japan.
Kanematsu A; Immunotherapy Division, Shizuoka Cancer Center Research Institute, Shizuoka 411-8777, Japan.
Kikuchi Y; Immunotherapy Division, Shizuoka Cancer Center Research Institute, Shizuoka 411-8777, Japan.
Nagashima T; Cancer Diagnostics Research Division, Shizuoka Cancer Center Research Institute, Shizuoka 411-8777, Japan.; SRL, Inc., Tokyo 163-0409, Japan.
Urakami K; Cancer Diagnostics Research Division, Shizuoka Cancer Center Research Institute, Shizuoka 411-8777, Japan.
Shimoda Y; Cancer Diagnostics Research Division, Shizuoka Cancer Center Research Institute, Shizuoka 411-8777, Japan.
Ohshima K; Medical Genetics Division, Shizuoka Cancer Center Research Institute, Shizuoka 411-8777, Japan.
Shiomi A; Division of Colon and Rectal Surgery, Shizuoka Cancer Center Hospital, Shizuoka 411-8777, Japan.
Ohde Y; Division of Thoracic Surgery, Shizuoka Cancer Center Hospital, Shizuoka 411-8777, Japan.
Terashima M; Division of Gastric Surgery, Shizuoka Cancer Center Hospital, Shizuoka 411-8777, Japan.
Uesaka K; Division of Hepato-Biliary-Pancreatic Surgery, Shizuoka Cancer Center Hospital, Shizuoka 411-8777, Japan.
Mukaigawa T; Division of Head and Neck Surgery, Shizuoka Cancer Center Hospital, Shizuoka 411-8777, Japan.
Hirashima Y; Division of Gynecology, Shizuoka Cancer Center Hospital, Shizuoka 411-8777, Japan.
Yoshikawa S; Division of Dermatology, Shizuoka Cancer Center Hospital, Shizuoka 411-8777, Japan.
Katagiri H; Division of Orthopedic Oncology, Shizuoka Cancer Center Hospital, Shizuoka 411-8777, Japan.
Sugino T; Division of Pathology, Shizuoka Cancer Center Hospital, Shizuoka 411-8777, Japan.
Takahashi M; Division of Orthopedic Oncology, Shizuoka Cancer Center Hospital, Shizuoka 411-8777, Japan.
Kenmotsu H; Division of Thoracic Oncology, Shizuoka Cancer Center Hospital, Shizuoka 411-8777, Japan.
Yamaguchi K; Office of The President, Shizuoka Cancer Center, Shizuoka 411-8777, Japan.
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Źródło:
Oncology letters [Oncol Lett] 2023 Jun 13; Vol. 26 (2), pp. 324. Date of Electronic Publication: 2023 Jun 13 (Print Publication: 2023).
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Less necessity of adjuvant S-1 treatment in non-monarchE-eligible patients.
Autorzy:
Yu M; Department of General Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan.
Takada M; Department of General Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan.
Yamada H; Department of General Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan.
Fujimoto H; Department of General Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan.
Sakakibara J; Department of General Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan.
Yamamoto H; Department of General Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan.
Nagashima T; Department of General Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan.
Ohtsuka M; Department of General Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan.
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Źródło:
Cancer medicine [Cancer Med] 2023 Jun; Vol. 12 (12), pp. 13193-13203. Date of Electronic Publication: 2023 May 10.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Neoplasm Recurrence, Local*/drug therapy
Breast Neoplasms*
Humans ; Female ; Retrospective Studies ; Prognosis ; Combined Modality Therapy ; Chemotherapy, Adjuvant
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Molecular genetic positioning of small intestine and papilla of Vater carcinomas including clinicopathological classification.
Autorzy:
Nakamura M; Division of Hepato-Biliary-Pancreatic Surgery, Shizuoka Cancer Center, Shizuoka, Japan.; Department of Gastroenterological Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Okamura Y; Division of Hepato-Biliary-Pancreatic Surgery, Shizuoka Cancer Center, Shizuoka, Japan.; Department of Gastroenterological Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.; Division of Digestive Surgery, Department of Surgery, Nihon University School of Medicine, Tokyo, Japan.
Ohshima K; Medical Genetics Division, Shizuoka Cancer Center Research Institute, Shizuoka, Japan.
Sugiura T; Division of Hepato-Biliary-Pancreatic Surgery, Shizuoka Cancer Center, Shizuoka, Japan.
Ashida R; Division of Hepato-Biliary-Pancreatic Surgery, Shizuoka Cancer Center, Shizuoka, Japan.
Ohgi K; Division of Hepato-Biliary-Pancreatic Surgery, Shizuoka Cancer Center, Shizuoka, Japan.
Bando E; Division of Gastric Surgery, Shizuoka Cancer Center, Shizuoka, Japan.
Fujiya K; Division of Gastric Surgery, Shizuoka Cancer Center, Shizuoka, Japan.
Shiomi A; Division of Colon and Rectal Surgery, Shizuoka Cancer Center, Shizuoka, Japan.
Kagawa H; Division of Colon and Rectal Surgery, Shizuoka Cancer Center, Shizuoka, Japan.
Imamura T; Division of Hepato-Biliary-Pancreatic Surgery, Shizuoka Cancer Center, Shizuoka, Japan.
Nakayama G; Department of Gastroenterological Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Kodera Y; Department of Gastroenterological Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Uesaka K; Division of Hepato-Biliary-Pancreatic Surgery, Shizuoka Cancer Center, Shizuoka, Japan.
Ohike N; Division of Pathology, Shizuoka Cancer Center, Shizuoka, Japan.
Norose T; Division of Pathology, Shizuoka Cancer Center, Shizuoka, Japan.
Sasaki K; Division of Pathology, Shizuoka Cancer Center, Shizuoka, Japan.
Sugino T; Division of Pathology, Shizuoka Cancer Center, Shizuoka, Japan.
Ohnami S; Cancer Diagnostics Research Division, Shizuoka Cancer Center Research Institute, Shizuoka, Japan.
Nagashima T; Cancer Diagnostics Research Division, Shizuoka Cancer Center Research Institute, Shizuoka, Japan.; SRL, Inc., Tokyo, Japan.
Urakami K; Cancer Diagnostics Research Division, Shizuoka Cancer Center Research Institute, Shizuoka, Japan.
Akiyama Y; Immunotherapy Division, Shizuoka Cancer Center Research Institute, Shizuoka, Japan.
Yamaguchi K; Shizuoka Cancer Center Hospital and Research Institute, Shizuoka, Japan.
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Źródło:
Cancer medicine [Cancer Med] 2023 May; Vol. 12 (10), pp. 11491-11502. Date of Electronic Publication: 2023 Mar 31.
Typ publikacji:
Journal Article
MeSH Terms:
Ampulla of Vater*/pathology
Pancreatic Neoplasms*/pathology
Carcinoma, Pancreatic Ductal*/pathology
Adenocarcinoma*/pathology
Cholangiocarcinoma*/pathology
Bile Duct Neoplasms*/pathology
Humans ; Prognosis ; Intestine, Small/pathology ; Bile Ducts, Intrahepatic/pathology ; Molecular Biology ; Pancreatic Neoplasms
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
The impact of PIK3CA mutations and PTEN expression on the effect of neoadjuvant therapy for postmenopausal luminal breast cancer patients.
Autorzy:
Hayama S; Department of General Surgery, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-Ku, Chiba-Shi, Chiba, 260-8677, Japan.; Department of Breast Surgery, Chiba Cancer Center, 666-2 Nitona, Chuo-Ku, Chiba-Shi, Chiba, 260-8717, Japan.
Nakamura R; Department of Breast Surgery, Chiba Cancer Center, 666-2 Nitona, Chuo-Ku, Chiba-Shi, Chiba, 260-8717, Japan.
Ishige T; Department of Molecular Diagnosis, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-Ku, Chiba-Shi, Chiba, 260-8677, Japan.
Sangai T; Department of Breast and Thyroid Surgery, Kitasato University School of Medicine, 1-15-1 Kitazato Minami-Ku, Sagamihara, Kanagawa, 252-0374, Japan. .
Sakakibara M; Departments of Breast Surgery, Toho University Sakura Medical Center, 564-1 Shimoshizu, Sakura, Chiba, 285-8741, Japan.
Fujimoto H; Department of General Surgery, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-Ku, Chiba-Shi, Chiba, 260-8677, Japan.
Ishigami E; Department of General Surgery, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-Ku, Chiba-Shi, Chiba, 260-8677, Japan.
Masuda T; Department of General Surgery, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-Ku, Chiba-Shi, Chiba, 260-8677, Japan.
Nakagawa A; Department of General Surgery, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-Ku, Chiba-Shi, Chiba, 260-8677, Japan.
Teranaka R; Department of General Surgery, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-Ku, Chiba-Shi, Chiba, 260-8677, Japan.
Ota S; Department of Pathology, Chiba University Hospital, 1-8-1 Inohana, Chuo-Ku, Chiba-Shi, Chiba, 260-8677, Japan.
Itoga S; Department of Applied Genomics, Kazusa DNA Research Institute, 2-6-7 Kazusa-Kamatari, Kisarazu Chiba, 292-0818, Japan.
Yamamoto N; Department of Breast Surgery, Chiba Cancer Center, 666-2 Nitona, Chuo-Ku, Chiba-Shi, Chiba, 260-8717, Japan.
Nagashima T; Department of General Surgery, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-Ku, Chiba-Shi, Chiba, 260-8677, Japan.
Otsuka M; Department of General Surgery, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-Ku, Chiba-Shi, Chiba, 260-8677, Japan.
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Źródło:
BMC cancer [BMC Cancer] 2023 Apr 27; Vol. 23 (1), pp. 384. Date of Electronic Publication: 2023 Apr 27.
Typ publikacji:
Journal Article
MeSH Terms:
Breast Neoplasms*/drug therapy
Breast Neoplasms*/genetics
Humans ; Female ; Neoadjuvant Therapy ; Postmenopause ; Receptor, ErbB-2/metabolism ; PTEN Phosphohydrolase/genetics ; PTEN Phosphohydrolase/metabolism ; Class I Phosphatidylinositol 3-Kinases/genetics ; Mutation ; Biomarkers, Tumor/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Characterization of pancreatic cancer with ultra-low tumor mutational burden.
Autorzy:
Imamura T; Division of Hepato-Biliary-Pancreatic Surgery, Shizuoka Cancer Center, 1007 Shimonagakubo, Sunto-Nagaizumi, Shizuoka, 4118777, Japan.
Ashida R; Division of Hepato-Biliary-Pancreatic Surgery, Shizuoka Cancer Center, 1007 Shimonagakubo, Sunto-Nagaizumi, Shizuoka, 4118777, Japan. .
Ohshima K; Medical Genetics Division, Shizuoka Cancer Center Research Institute, Shizuoka, Japan.
Uesaka K; Division of Hepato-Biliary-Pancreatic Surgery, Shizuoka Cancer Center, 1007 Shimonagakubo, Sunto-Nagaizumi, Shizuoka, 4118777, Japan.
Sugiura T; Division of Hepato-Biliary-Pancreatic Surgery, Shizuoka Cancer Center, 1007 Shimonagakubo, Sunto-Nagaizumi, Shizuoka, 4118777, Japan.
Ohgi K; Division of Hepato-Biliary-Pancreatic Surgery, Shizuoka Cancer Center, 1007 Shimonagakubo, Sunto-Nagaizumi, Shizuoka, 4118777, Japan.
Yamada M; Division of Hepato-Biliary-Pancreatic Surgery, Shizuoka Cancer Center, 1007 Shimonagakubo, Sunto-Nagaizumi, Shizuoka, 4118777, Japan.
Otsuka S; Division of Hepato-Biliary-Pancreatic Surgery, Shizuoka Cancer Center, 1007 Shimonagakubo, Sunto-Nagaizumi, Shizuoka, 4118777, Japan.
Hatakeyama K; Cancer Multiomics Division, Shizuoka Cancer Center Research Institute, Shizuoka, Japan.
Nagashima T; Cancer Diagnostics Research Division, Shizuoka Cancer Center Research Institute, Shizuoka, Japan.; SRL, Inc., Tokyo, Japan.
Sugino T; Division of Pathology, Shizuoka Cancer Center, Shizuoka, Japan.
Urakami K; Cancer Diagnostics Research Division, Shizuoka Cancer Center Research Institute, Shizuoka, Japan.
Akiyama Y; Immunotherapy Division, Shizuoka Cancer Center Research Institute, Shizuoka, Japan.
Yamaguchi K; Shizuoka Cancer Center Hospital and Research Institute, Shizuoka, Japan.
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Źródło:
Scientific reports [Sci Rep] 2023 Mar 16; Vol. 13 (1), pp. 4359. Date of Electronic Publication: 2023 Mar 16.
Typ publikacji:
Journal Article
MeSH Terms:
DNA Copy Number Variations*
Pancreatic Neoplasms*/genetics
Humans ; Mutation ; Prognosis ; Biomarkers, Tumor/genetics ; Pancreatic Neoplasms
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Characterization of rare histological subtypes of ovarian cancer based on molecular profiling.
Autorzy:
Takahashi N; Division of Gynecology, Shizuoka Cancer Center, Sunto-gun, Shizuoka, Japan.
Hatakeyama K; Medical Genetics Division, Shizuoka Cancer Center Research Institute, Sunto-gun, Shizuoka, Japan.
Nagashima T; Cancer Diagnostics Research Division, Shizuoka Cancer Center Research Institute, Sunto-gun, Shizuoka, Japan.; SRL Inc., Shinjuku-ku, Tokyo, Japan.
Ohshima K; Medical Genetics Division, Shizuoka Cancer Center Research Institute, Sunto-gun, Shizuoka, Japan.
Urakami K; Cancer Diagnostics Research Division, Shizuoka Cancer Center Research Institute, Sunto-gun, Shizuoka, Japan.
Yamaguchi K; Shizuoka Cancer Center, Sunto-gun, Shizuoka, Japan.
Hirashima Y; Division of Gynecology, Shizuoka Cancer Center, Sunto-gun, Shizuoka, Japan.
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Źródło:
Cancer medicine [Cancer Med] 2023 Jan; Vol. 12 (1), pp. 387-395. Date of Electronic Publication: 2022 Jun 08.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Ovarian Neoplasms*/genetics
Ovarian Neoplasms*/pathology
Carcinoma*
Humans ; Female ; Germ-Line Mutation ; BRCA1 Protein/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Infection control for COVID-19 in hospital examination room.
Autorzy:
Takada M; Safety and Health Organization, Chiba University, 1-33, Yayoi-Cho, Inage-ku, Chiba, Chiba, Japan. .; Department of General Surgery, Chiba University, Graduate School of Medicine, Chiba, Japan. .
Fukushima T; Department of Mechanical Engineering, Graduate School of Engineering, Chiba University, Chiba, Japan.
Ozawa S; Department of Mechanical Engineering, Graduate School of Engineering, Chiba University, Chiba, Japan.
Matsubara S; Department of Mechanical Engineering, Graduate School of Engineering, Chiba University, Chiba, Japan.
Suzuki T; Department of Otorhinolaryngology/Head and Neck Surgery, Chiba University, Graduate School of Medicine, Chiba, Japan.
Fukumoto I; Department of Otorhinolaryngology/Head and Neck Surgery, Chiba University, Graduate School of Medicine, Chiba, Japan.
Hanazawa T; Department of Otorhinolaryngology/Head and Neck Surgery, Chiba University, Graduate School of Medicine, Chiba, Japan.
Nagashima T; Department of General Surgery, Chiba University, Graduate School of Medicine, Chiba, Japan.
Uruma R; Safety and Health Organization, Chiba University, 1-33, Yayoi-Cho, Inage-ku, Chiba, Chiba, Japan.
Otsuka M; Department of General Surgery, Chiba University, Graduate School of Medicine, Chiba, Japan.
Tanaka G; Department of Mechanical Engineering, Graduate School of Engineering, Chiba University, Chiba, Japan.
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Źródło:
Scientific reports [Sci Rep] 2022 Oct 29; Vol. 12 (1), pp. 18230. Date of Electronic Publication: 2022 Oct 29.
Typ publikacji:
Journal Article
MeSH Terms:
COVID-19*/prevention & control
Humans ; SARS-CoV-2 ; Infectious Disease Transmission, Patient-to-Professional/prevention & control ; Respiratory Aerosols and Droplets ; Infection Control ; Cough ; Hospitals
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Overview and clinical significance of multiple mutations in individual genes in hepatocellular carcinoma.
Autorzy:
Imamura T; Division of Hepato-Biliary-Pancreatic Surgery, Shizuoka Cancer Center, 1007 Shimonagakubo, Sunto-Nagaizumi, Shizuoka, 4118777, Japan.
Okamura Y; Division of Hepato-Biliary-Pancreatic Surgery, Shizuoka Cancer Center, 1007 Shimonagakubo, Sunto-Nagaizumi, Shizuoka, 4118777, Japan. .; Department of Digestive Surgery, Nihon University School of Medicine, Tokyo, Japan. .
Ohshima K; Medical Genetics Division, Shizuoka Cancer Center Research Institute, Shizuoka, Japan.
Uesaka K; Division of Hepato-Biliary-Pancreatic Surgery, Shizuoka Cancer Center, 1007 Shimonagakubo, Sunto-Nagaizumi, Shizuoka, 4118777, Japan.
Sugiura T; Division of Hepato-Biliary-Pancreatic Surgery, Shizuoka Cancer Center, 1007 Shimonagakubo, Sunto-Nagaizumi, Shizuoka, 4118777, Japan.
Ito T; Division of Hepato-Biliary-Pancreatic Surgery, Shizuoka Cancer Center, 1007 Shimonagakubo, Sunto-Nagaizumi, Shizuoka, 4118777, Japan.
Yamamoto Y; Division of Hepato-Biliary-Pancreatic Surgery, Shizuoka Cancer Center, 1007 Shimonagakubo, Sunto-Nagaizumi, Shizuoka, 4118777, Japan.
Ashida R; Division of Hepato-Biliary-Pancreatic Surgery, Shizuoka Cancer Center, 1007 Shimonagakubo, Sunto-Nagaizumi, Shizuoka, 4118777, Japan.
Ohgi K; Division of Hepato-Biliary-Pancreatic Surgery, Shizuoka Cancer Center, 1007 Shimonagakubo, Sunto-Nagaizumi, Shizuoka, 4118777, Japan.
Otsuka S; Division of Hepato-Biliary-Pancreatic Surgery, Shizuoka Cancer Center, 1007 Shimonagakubo, Sunto-Nagaizumi, Shizuoka, 4118777, Japan.
Ohnami S; Cancer Diagnostics Research Division, Shizuoka Cancer Center Research Institute, Shizuoka, Japan.
Nagashima T; Cancer Diagnostics Research Division, Shizuoka Cancer Center Research Institute, Shizuoka, Japan.; SRL, Inc., Tokyo, Japan.
Hatakeyama K; Medical Genetics Division, Shizuoka Cancer Center Research Institute, Shizuoka, Japan.
Sugino T; Division of Pathology, Shizuoka Cancer Center, Shizuoka, Japan.
Urakami K; Cancer Diagnostics Research Division, Shizuoka Cancer Center Research Institute, Shizuoka, Japan.
Akiyama Y; Immunotherapy Division, Shizuoka Cancer Center Research Institute, Shizuoka, Japan.
Yamaguchi K; Shizuoka Cancer Center Hospital and Research Institute, Shizuoka, Japan.
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Źródło:
BMC cancer [BMC Cancer] 2022 Oct 05; Vol. 22 (1), pp. 1046. Date of Electronic Publication: 2022 Oct 05.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Hepatocellular*/genetics
Carcinoma, Hepatocellular*/pathology
Liver Neoplasms*/genetics
Liver Neoplasms*/pathology
Biomarkers, Tumor/genetics ; Humans ; Mucins/genetics ; Mutation ; Prognosis ; RNA, Messenger
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Hepatocellular carcinoma after a sustained virological response by direct-acting antivirals harbors TP53 inactivation.
Autorzy:
Imamura T; Division of Hepato-Biliary-Pancreatic Surgery, Shizuoka Cancer Center, Shizuoka, Japan.
Okamura Y; Division of Hepato-Biliary-Pancreatic Surgery, Shizuoka Cancer Center, Shizuoka, Japan.; Department of Digestive Surgery, Nihon University School of Medicine, Tokyo, Japan.
Ohshima K; Medical Genetics Division, Shizuoka Cancer Center Research Institute, Shizuoka, Japan.
Uesaka K; Division of Hepato-Biliary-Pancreatic Surgery, Shizuoka Cancer Center, Shizuoka, Japan.
Sugiura T; Division of Hepato-Biliary-Pancreatic Surgery, Shizuoka Cancer Center, Shizuoka, Japan.
Ito T; Division of Hepato-Biliary-Pancreatic Surgery, Shizuoka Cancer Center, Shizuoka, Japan.
Yamamoto Y; Division of Hepato-Biliary-Pancreatic Surgery, Shizuoka Cancer Center, Shizuoka, Japan.
Ashida R; Division of Hepato-Biliary-Pancreatic Surgery, Shizuoka Cancer Center, Shizuoka, Japan.
Ohgi K; Division of Hepato-Biliary-Pancreatic Surgery, Shizuoka Cancer Center, Shizuoka, Japan.
Otsuka S; Division of Hepato-Biliary-Pancreatic Surgery, Shizuoka Cancer Center, Shizuoka, Japan.
Ohnami S; Cancer Diagnostics Research Division, Shizuoka Cancer Center Research Institute, Shizuoka, Japan.
Nagashima T; Cancer Diagnostics Research Division, Shizuoka Cancer Center Research Institute, Shizuoka, Japan.; SRL, Inc., Tokyo, Japan.
Hatakeyama K; Medical Genetics Division, Shizuoka Cancer Center Research Institute, Shizuoka, Japan.
Kakuda Y; Division of Pathology, Shizuoka Cancer Center, Shizuoka, Japan.
Sugino T; Division of Pathology, Shizuoka Cancer Center, Shizuoka, Japan.
Urakami K; Cancer Diagnostics Research Division, Shizuoka Cancer Center Research Institute, Shizuoka, Japan.
Akiyama Y; Immunotherapy Division, Shizuoka Cancer Center Research Institute, Shizuoka, Japan.
Yamaguchi K; Shizuoka Cancer Center Hospital and Research Institute, Shizuoka, Japan.
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Źródło:
Cancer medicine [Cancer Med] 2022 Apr; Vol. 11 (8), pp. 1769-1786. Date of Electronic Publication: 2022 Feb 17.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Hepatocellular*/drug therapy
Carcinoma, Hepatocellular*/genetics
Hepatitis C*/complications
Hepatitis C*/drug therapy
Hepatitis C*/genetics
Hepatitis C, Chronic*/complications
Hepatitis C, Chronic*/drug therapy
Hepatitis C, Chronic*/genetics
Liver Neoplasms*/complications
Liver Neoplasms*/drug therapy
Liver Neoplasms*/genetics
Antiviral Agents/pharmacology ; Antiviral Agents/therapeutic use ; Hepacivirus/genetics ; Humans ; Interferons ; Phosphatidylinositol 3-Kinases ; Tumor Suppressor Protein p53/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Tumor cell enrichment by tissue suspension enables detection of mutations with low variant allele frequency and estimation of germline mutations.
Autorzy:
Hatakeyama K; Medical Genetics Division, Shizuoka Cancer Center Research Institute, Sunto-gun, Shizuoka, 411-8777, Japan. .
Muramatsu K; Division of Pathology, Shizuoka Cancer Center Research Institute, Sunto-gun, Shizuoka, 411-8777, Japan.
Nagashima T; Cancer Diagnostics Research Division, Shizuoka Cancer Center Research Institute, Sunto-gun, Shizuoka, 411-8777, Japan.; SRL Inc, Shinjuku-ku, Tokyo, 163-0409, Japan.
Kawanishi Y; SRL & Shizuoka Cancer Center Collaborative Laboratories Inc, Sunto-gun, Shizuoka, 411-8777, Japan.
Fukumura R; SRL & Shizuoka Cancer Center Collaborative Laboratories Inc, Sunto-gun, Shizuoka, 411-8777, Japan.
Ohshima K; Medical Genetics Division, Shizuoka Cancer Center Research Institute, Sunto-gun, Shizuoka, 411-8777, Japan.
Shimoda Y; Cancer Diagnostics Research Division, Shizuoka Cancer Center Research Institute, Sunto-gun, Shizuoka, 411-8777, Japan.; SRL Inc, Shinjuku-ku, Tokyo, 163-0409, Japan.
Kenmotsu H; Division of Genetic Medicine Promotion, Shizuoka Cancer Center, Sunto-gun, Shizuoka, 411-8777, Japan.
Mochizuki T; Medical Genetics Division, Shizuoka Cancer Center Research Institute, Sunto-gun, Shizuoka, 411-8777, Japan.
Urakami K; Cancer Diagnostics Research Division, Shizuoka Cancer Center Research Institute, Sunto-gun, Shizuoka, 411-8777, Japan.
Akiyama Y; Immunotheraphy Division, Shizuoka Cancer Center Research Institute, Sunto-gun, Shizuoka, 411-8777, Japan.
Sugino T; Division of Pathology, Shizuoka Cancer Center Research Institute, Sunto-gun, Shizuoka, 411-8777, Japan.
Yamaguchi K; Shizuoka Cancer Center, Sunto-gun, Shizuoka, 411-8777, Japan.
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Źródło:
Scientific reports [Sci Rep] 2022 Feb 22; Vol. 12 (1), pp. 2953. Date of Electronic Publication: 2022 Feb 22.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Alleles*
Gene Frequency*
Germ-Line Mutation*
High-Throughput Nucleotide Sequencing*
Stomach Neoplasms/*genetics
Female ; Humans ; Male ; Stomach Neoplasms/epidemiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Identification of tumor microenvironment-associated immunological genes as potent prognostic markers in the cancer genome analysis project HOPE.
Autorzy:
Kondou R; Division of Immunotherapy, Shizuoka Cancer Center Research Institute, Shizuoka 411-8777, Japan.
Akiyama Y; Division of Immunotherapy, Shizuoka Cancer Center Research Institute, Shizuoka 411-8777, Japan.
Iizuka A; Division of Immunotherapy, Shizuoka Cancer Center Research Institute, Shizuoka 411-8777, Japan.
Miyata H; Division of Immunotherapy, Shizuoka Cancer Center Research Institute, Shizuoka 411-8777, Japan.
Maeda C; Division of Immunotherapy, Shizuoka Cancer Center Research Institute, Shizuoka 411-8777, Japan.
Kanematsu A; Division of Immunotherapy, Shizuoka Cancer Center Research Institute, Shizuoka 411-8777, Japan.
Watanabe K; Division of Immunotherapy, Shizuoka Cancer Center Research Institute, Shizuoka 411-8777, Japan.
Ashizawa T; Division of Immunotherapy, Shizuoka Cancer Center Research Institute, Shizuoka 411-8777, Japan.
Nagashima T; Division of Cancer Diagnostics Research, Shizuoka Cancer Center Research Institute, Shizuoka 411-8777, Japan.; Special Reference Laboratory, Tokyo 191-0002, Japan.
Urakami K; Division of Cancer Diagnostics Research, Shizuoka Cancer Center Research Institute, Shizuoka 411-8777, Japan.
Shimoda Y; Division of Cancer Diagnostics Research, Shizuoka Cancer Center Research Institute, Shizuoka 411-8777, Japan.; Special Reference Laboratory, Tokyo 191-0002, Japan.
Ohshima K; Medical Genetics Division, Shizuoka Cancer Center Research Institute, Shizuoka 411-8777, Japan.
Shiomi A; Division of Colon and Rectal Surgery, Shizuoka Cancer Center Hospital, Shizuoka 411-8777, Japan.
Ohde Y; Division of Thoracic Surgery, Shizuoka Cancer Center Hospital, Shizuoka 411-8777, Japan.
Terashima M; Division of Gastric Surgery, Shizuoka Cancer Center Hospital, Shizuoka 411-8777, Japan.
Uesaka K; Division of Hepato-Biliary-Pancreatic Surgery, Shizuoka Cancer Center Hospital, Shizuoka 411-8777, Japan.
Onitsuka T; Division of Head and Neck Surgery, Shizuoka Cancer Center Hospital, Shizuoka 411-8777, Japan.
Nishimura S; Division of Breast Surgery, Shizuoka Cancer Center Hospital, Shizuoka 411-8777, Japan.
Hirashima Y; Division of Gynecology, Shizuoka Cancer Center Hospital, Shizuoka 411-8777, Japan.
Hayashi N; Division of Neurosurgery, Shizuoka Cancer Center Hospital, Shizuoka 411-8777, Japan.
Kiyohara Y; Division of Dermatology, Shizuoka Cancer Center Hospital, Shizuoka 411-8777, Japan.
Tsubosa Y; Division of Esophageal Surgery, Shizuoka Cancer Center Hospital, Shizuoka 411-8777, Japan.
Katagiri H; Division of Orthopedic Oncology, Shizuoka Cancer Center Hospital, Shizuoka 411-8777, Japan.
Niwakawa M; Division of Urology, Shizuoka Cancer Center Hospital, Shizuoka 411-8777, Japan.
Takahashi K; Division of Breast Oncology Center, Shizuoka Cancer Center Hospital, Shizuoka 411-8777, Japan.
Kashiwagi H; Division of Ophthalmology, Shizuoka Cancer Center Hospital, Shizuoka 411-8777, Japan.
Nakagawa M; Division of Plastic and Reconstructive Surgery, Shizuoka Cancer Center Hospital, Shizuoka 411-8777, Japan.
Ishida Y; Division of Pediatrics, Shizuoka Cancer Center Hospital, Shizuoka 411-8777, Japan.
Sugino T; Division of Pathology, Shizuoka Cancer Center Hospital, Shizuoka 411-8777, Japan.
Notsu A; Clinical Trial Coordination Office, Shizuoka Cancer Center Hospital, Shizuoka 411-8777, Japan.
Mori K; Clinical Trial Coordination Office, Shizuoka Cancer Center Hospital, Shizuoka 411-8777, Japan.
Takahashi M; Division of Orthopedic Oncology, Shizuoka Cancer Center Hospital, Shizuoka 411-8777, Japan.
Kenmotsu H; Division of Thoracic Oncology, Shizuoka Cancer Center Hospital, Shizuoka 411-8777, Japan.
Yamaguchi K; Shizuoka Cancer Center, Shizuoka 411-8777, Japan.
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Źródło:
Molecular and clinical oncology [Mol Clin Oncol] 2021 Nov; Vol. 15 (5), pp. 232. Date of Electronic Publication: 2021 Sep 13.
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Comprehensive genomic analysis contrasting primary colorectal cancer and matched liver metastases.
Autorzy:
Shiomi A; Division of Colon and Rectal Surgery, Shizuoka Cancer Center, Shizuoka 411-8777, Japan.; Division of Gene Regulation Institute for Advanced Medical Research, Keio University School of Medicine, Tokyo 160-858, Japan.
Kusuhara M; Regional Resources Division, Shizuoka Cancer Center Research Institute, Shizuoka 411-8777, Japan.
Sugino T; Division of Pathology, Shizuoka Cancer Center, Shizuoka 411-8777, Japan.
Sugiura T; Division of Hepato-Biliary-Pancreatic Surgery, Shizuoka Cancer Center, Shizuoka 411-8777, Japan.
Ohshima K; Medical Genetics Division, Shizuoka Cancer Center Research Institute, Shizuoka 411-8777, Japan.
Nagashima T; Cancer Diagnostics Research Division, Shizuoka Cancer Center Research Institute, Shizuoka 411-8777, Japan.; SRL, Inc., Tokyo 163-0409, Japan.
Urakami K; Cancer Diagnostics Research Division, Shizuoka Cancer Center Research Institute, Shizuoka 411-8777, Japan.
Serizawa M; Drug Discovery and Development Division, Shizuoka Cancer Center Research Institute, Shizuoka 411-8777, Japan.
Saya H; Division of Gene Regulation Institute for Advanced Medical Research, Keio University School of Medicine, Tokyo 160-858, Japan.
Yamaguchi K; Shizuoka Cancer Center, Shizuoka 411-8777, Japan.
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Źródło:
Oncology letters [Oncol Lett] 2021 Jun; Vol. 21 (6), pp. 466. Date of Electronic Publication: 2021 Apr 12.
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Mutational concordance analysis provides supportive information for double cancer diagnosis.
Autorzy:
Hatakeyama K; Medical Genetics Division, Shizuoka Cancer Center Research Institute, Sunto-gun, Shizuoka, 411-8777, Japan. .
Nagashima T; Cancer Diagnostics Research Division, Shizuoka Cancer Center Research Institute, Sunto-gun, Shizuoka, 411-8777, Japan.; SRL Inc., Shinjuku-ku, Tokyo, 163-0409, Japan.
Notsu A; Clinical Research Center, Shizuoka Cancer Center, Sunto-gun, Shizuoka, 411-8777, Japan.
Ohshima K; Medical Genetics Division, Shizuoka Cancer Center Research Institute, Sunto-gun, Shizuoka, 411-8777, Japan.
Ohnami S; Cancer Diagnostics Research Division, Shizuoka Cancer Center Research Institute, Sunto-gun, Shizuoka, 411-8777, Japan.
Ohnami S; Cancer Diagnostics Research Division, Shizuoka Cancer Center Research Institute, Sunto-gun, Shizuoka, 411-8777, Japan.
Shimoda Y; Cancer Diagnostics Research Division, Shizuoka Cancer Center Research Institute, Sunto-gun, Shizuoka, 411-8777, Japan.; SRL Inc., Shinjuku-ku, Tokyo, 163-0409, Japan.
Naruoka A; Drug Discovery and Development Division, Shizuoka Cancer Center Research Institute, Sunto-gun, Shizuoka, 411-8777, Japan.
Maruyama K; Experimental Animal Facility, Shizuoka Cancer Center Research Institute, Sunto-gun, Shizuoka, 411-8777, Japan.
Iizuka A; Immunotheraphy Division, Shizuoka Cancer Center Research Institute, Sunto-gun, Shizuoka, 411-8777, Japan.
Ashizawa T; Immunotheraphy Division, Shizuoka Cancer Center Research Institute, Sunto-gun, Shizuoka, 411-8777, Japan.
Kenmotsu H; Division of Genetic Medicine Promotion, Shizuoka Cancer Center, Sunto-gun, Shizuoka, 411-8777, Japan.
Mochizuki T; Medical Genetics Division, Shizuoka Cancer Center Research Institute, Sunto-gun, Shizuoka, 411-8777, Japan.
Urakami K; Cancer Diagnostics Research Division, Shizuoka Cancer Center Research Institute, Sunto-gun, Shizuoka, 411-8777, Japan.
Akiyama Y; Immunotheraphy Division, Shizuoka Cancer Center Research Institute, Sunto-gun, Shizuoka, 411-8777, Japan.
Yamaguchi K; Shizuoka Cancer Center, Sunto-gun, Shizuoka, 411-8777, Japan.
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Źródło:
BMC cancer [BMC Cancer] 2021 Feb 19; Vol. 21 (1), pp. 181. Date of Electronic Publication: 2021 Feb 19.
Typ publikacji:
Journal Article
MeSH Terms:
Mutation*
Biomarkers, Tumor/*genetics
Neoplasms/*genetics
Neoplasms, Second Primary/*genetics
Cohort Studies ; Computational Biology/methods ; DNA Mutational Analysis/methods ; Databases, Genetic ; Humans ; Japan/epidemiology ; Neoplasm Metastasis ; Neoplasms/diagnosis ; Neoplasms/epidemiology ; Neoplasms/pathology ; Neoplasms, Second Primary/diagnosis ; Neoplasms, Second Primary/epidemiology ; Neoplasms, Second Primary/pathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Assessment of associations between clinical and immune microenvironmental factors and tumor mutation burden in resected nonsmall cell lung cancer by applying machine learning to whole-slide images.
Autorzy:
Ono A; Division of Thoracic Oncology, Shizuoka Cancer Center, Shizuoka, Japan.
Terada Y; Division of Thoracic Surgery, Shizuoka Cancer Center, Shizuoka, Japan.
Kawata T; Division of Pathology, Shizuoka Cancer Center, Shizuoka, Japan.
Serizawa M; Drug Discovery and Development Division, Shizuoka Cancer Center Research Institute, Shizuoka Cancer Center, Shizuoka, Japan.
Isaka M; Division of Thoracic Surgery, Shizuoka Cancer Center, Shizuoka, Japan.
Kawabata T; Clinical Research Center, Shizuoka Cancer Center, Shizuoka, Japan.
Imai T; Department of Clinical Biostatistics, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Mori K; Clinical Research Center, Shizuoka Cancer Center, Shizuoka, Japan.
Muramatsu K; Division of Pathology, Shizuoka Cancer Center, Shizuoka, Japan.
Hayashi I; Division of Pathology, Shizuoka Cancer Center, Shizuoka, Japan.
Kenmotsu H; Division of Thoracic Oncology, Shizuoka Cancer Center, Shizuoka, Japan.
Ohshima K; Medical Genetics Division, Shizuoka Cancer Center Research Institute, Shizuoka Cancer Center, Shizuoka, Japan.
Urakami K; Cancer Diagnostics Research Division, Shizuoka Cancer Center Research Institute, Shizuoka Cancer Center, Shizuoka, Japan.
Nagashima T; Cancer Diagnostics Research Division, Shizuoka Cancer Center Research Institute, Shizuoka Cancer Center, Shizuoka, Japan.; SRL Inc, Tokyo, Japan.
Kusuhara M; Region Resources Division, Shizuoka Cancer Center Research Institute, Shizuoka Cancer Center, Shizuoka, Japan.
Akiyama Y; Immunotherapy Division, Shizuoka Cancer Center Research Institute, Shizuoka Cancer Center, Shizuoka, Japan.
Sugino T; Division of Pathology, Shizuoka Cancer Center, Shizuoka, Japan.
Ohde Y; Division of Thoracic Surgery, Shizuoka Cancer Center, Shizuoka, Japan.
Yamaguchi K; Shizuoka Cancer Center, Shizuoka, Japan.
Takahashi T; Division of Thoracic Oncology, Shizuoka Cancer Center, Shizuoka, Japan.
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Źródło:
Cancer medicine [Cancer Med] 2020 Jul; Vol. 9 (13), pp. 4864-4875. Date of Electronic Publication: 2020 May 12.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Machine Learning*
Mutation*
Carcinoma, Non-Small-Cell Lung/*genetics
Carcinoma, Non-Small-Cell Lung/*immunology
Lung Neoplasms/*genetics
Tumor Microenvironment/*immunology
Adenocarcinoma/blood ; Adenocarcinoma/genetics ; Adenocarcinoma/immunology ; Adenocarcinoma/pathology ; Adult ; Aged ; Aged, 80 and over ; Antigens, Neoplasm/blood ; B7-H1 Antigen/blood ; Carcinoembryonic Antigen/blood ; Carcinoma, Non-Small-Cell Lung/blood ; Carcinoma, Non-Small-Cell Lung/pathology ; Carcinoma, Squamous Cell/blood ; Carcinoma, Squamous Cell/immunology ; Carcinoma, Squamous Cell/pathology ; Ex-Smokers ; Female ; Forkhead Transcription Factors/blood ; Humans ; Keratin-19/blood ; Lung Neoplasms/blood ; Lung Neoplasms/immunology ; Lung Neoplasms/pathology ; Lymphocytes, Tumor-Infiltrating/pathology ; Male ; Middle Aged ; Non-Smokers ; Regression Analysis ; Smokers ; Exome Sequencing
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Germline mismatch repair gene variants analyzed by universal sequencing in Japanese cancer patients.
Autorzy:
Kiyozumi Y; Division of Genetic Medicine Promotion, Shizuoka Cancer Center, Shizuoka, Japan.
Matsubayashi H; Division of Genetic Medicine Promotion, Shizuoka Cancer Center, Shizuoka, Japan.; Division of Endoscopy, Shizuoka Cancer Center, Shizuoka, Japan.
Horiuchi Y; Division of Genetic Medicine Promotion, Shizuoka Cancer Center, Shizuoka, Japan.; Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan.
Higashigawa S; Division of Genetic Medicine Promotion, Shizuoka Cancer Center, Shizuoka, Japan.
Oishi T; Division of Pathology, Shizuoka Cancer Center, Shizuoka, Japan.
Abe M; Division of Pathology, Shizuoka Cancer Center, Shizuoka, Japan.
Ohnami S; Shizuoka Cancer Center Research Institute, Shizuoka, Japan.
Urakami K; Shizuoka Cancer Center Research Institute, Shizuoka, Japan.
Nagashima T; Shizuoka Cancer Center Research Institute, Shizuoka, Japan.; SRL Inc., Tokyo, Japan.
Kusuhara M; Shizuoka Cancer Center Research Institute, Shizuoka, Japan.
Miyake H; Department of Genetic Counseling, Graduate School of Ochanomizu University, Tokyo, Japan.
Yamaguchi K; Shizuoka Cancer Center Research Institute, Shizuoka, Japan.
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Źródło:
Cancer medicine [Cancer Med] 2019 Sep; Vol. 8 (12), pp. 5534-5543. Date of Electronic Publication: 2019 Aug 06.
Typ publikacji:
Journal Article
MeSH Terms:
Germ-Line Mutation*
Colorectal Neoplasms, Hereditary Nonpolyposis/*genetics
DNA-Binding Proteins/*genetics
High-Throughput Nucleotide Sequencing/*methods
Mismatch Repair Endonuclease PMS2/*genetics
MutL Protein Homolog 1/*genetics
MutS Homolog 2 Protein/*genetics
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Child ; Colorectal Neoplasms, Hereditary Nonpolyposis/metabolism ; DNA Mismatch Repair ; DNA-Binding Proteins/metabolism ; Female ; Humans ; Japan ; Male ; Microsatellite Instability ; Middle Aged ; Mismatch Repair Endonuclease PMS2/metabolism ; MutL Protein Homolog 1/metabolism ; MutS Homolog 2 Protein/metabolism ; Proto-Oncogene Proteins B-raf/genetics ; Sequence Analysis, DNA ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Clinicopathological and mutational analyses of colorectal cancer with mutations in the POLE gene.
Autorzy:
Hino H; Division of Colon and Rectal Surgery, Shizuoka Cancer Center Hospital, Shizuoka, Japan.
Shiomi A; Division of Colon and Rectal Surgery, Shizuoka Cancer Center Hospital, Shizuoka, Japan.
Kusuhara M; Regional Resources Division, Shizuoka Cancer Center Research Institute, Shizuoka, Japan.
Kagawa H; Division of Colon and Rectal Surgery, Shizuoka Cancer Center Hospital, Shizuoka, Japan.
Yamakawa Y; Division of Colon and Rectal Surgery, Shizuoka Cancer Center Hospital, Shizuoka, Japan.
Hatakeyama K; Medical Genetics Division, Shizuoka Cancer Center Research Institute, Shizuoka, Japan.
Kawabata T; Clinical Research Promotion Unit, Clinical Research Center, Shizuoka Cancer Center, Shizuoka, Japan.
Oishi T; Division of Pathology, Shizuoka Cancer Center Hospital, Shizuoka, Japan.
Urakami K; Cancer Diagnostics Research Division, Shizuoka Cancer Center Research Institute, Shizuoka, Japan.
Nagashima T; SRL Inc, Tokyo, Japan.
Kinugasa Y; Division of Colon and Rectal Surgery, Shizuoka Cancer Center Hospital, Shizuoka, Japan.; Department of Gastrointestinal Surgery, Tokyo Medical and Dental University, Tokyo, Japan.
Yamaguchi K; Shizuoka Cancer Center Hospital and Research Institute, Shizuoka, Japan.
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Źródło:
Cancer medicine [Cancer Med] 2019 Aug; Vol. 8 (10), pp. 4587-4597. Date of Electronic Publication: 2019 Jun 25.
Typ publikacji:
Journal Article
MeSH Terms:
Mutation*
Colorectal Neoplasms/*pathology
DNA Polymerase II/*genetics
Poly-ADP-Ribose Binding Proteins/*genetics
Exome Sequencing/*methods
Adult ; Age Factors ; Aged ; Aged, 80 and over ; Colorectal Neoplasms/genetics ; DNA Polymerase II/chemistry ; Female ; Gene Expression Profiling ; Gene Expression Regulation, Neoplastic ; Humans ; Male ; Middle Aged ; Poly-ADP-Ribose Binding Proteins/chemistry ; Protein Domains ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Phase II study of neoadjuvant anthracycline combined with nanoparticle albumin-bound paclitaxel for human epidermal growth factor receptor 2-negative breast cancer.
Autorzy:
Ishigami E; Department of General Surgery, Chiba University Graduate School of Medicine, Chiba, Chiba 260-8670, Japan.
Sakakibara M; Department of General Surgery, Chiba University Graduate School of Medicine, Chiba, Chiba 260-8670, Japan.
Sakakibara J; Department of General Surgery, Chiba University Graduate School of Medicine, Chiba, Chiba 260-8670, Japan.
Iwase T; Department of General Surgery, Chiba University Graduate School of Medicine, Chiba, Chiba 260-8670, Japan.
Hayama S; Department of General Surgery, Chiba University Graduate School of Medicine, Chiba, Chiba 260-8670, Japan.
Masuda T; Department of General Surgery, Chiba University Graduate School of Medicine, Chiba, Chiba 260-8670, Japan.
Nakagawa A; Department of General Surgery, Chiba University Graduate School of Medicine, Chiba, Chiba 260-8670, Japan.
Nagashima T; Department of General Surgery, Chiba University Graduate School of Medicine, Chiba, Chiba 260-8670, Japan.
Sangai T; Department of General Surgery, Chiba University Graduate School of Medicine, Chiba, Chiba 260-8670, Japan.
Fujimoto H; Department of General Surgery, Chiba University Graduate School of Medicine, Chiba, Chiba 260-8670, Japan.
Otsuka M; Department of General Surgery, Chiba University Graduate School of Medicine, Chiba, Chiba 260-8670, Japan.
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Źródło:
Molecular and clinical oncology [Mol Clin Oncol] 2017 Dec; Vol. 7 (6), pp. 1079-1082. Date of Electronic Publication: 2017 Oct 20.
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
An increased neutrophil-to-lymphocyte ratio predicts poorer survival following recurrence for patients with breast cancer.
Autorzy:
Iwase T; Department of General Surgery, Chiba University Hospital, Chiba 2608677, Japan.
Sangai T; Department of General Surgery, Chiba University Hospital, Chiba 2608677, Japan.
Sakakibara M; Department of General Surgery, Chiba University Hospital, Chiba 2608677, Japan.
Sakakibara J; Department of General Surgery, Chiba University Hospital, Chiba 2608677, Japan.
Ishigami E; Department of General Surgery, Chiba University Hospital, Chiba 2608677, Japan.
Hayama S; Department of General Surgery, Chiba University Hospital, Chiba 2608677, Japan.
Nakagawa A; Department of General Surgery, Chiba University Hospital, Chiba 2608677, Japan.
Masuda T; Department of General Surgery, Chiba University Hospital, Chiba 2608677, Japan.
Tabe S; Department of General Surgery, Chiba University Hospital, Chiba 2608677, Japan.
Nagashima T; Department of General Surgery, Chiba University Hospital, Chiba 2608677, Japan.
Pokaż więcej
Źródło:
Molecular and clinical oncology [Mol Clin Oncol] 2017 Feb; Vol. 6 (2), pp. 266-270. Date of Electronic Publication: 2016 Dec 05.
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
TAK1 maintains the survival of immunoglobulin λ-chain-positive B cells.
Autorzy:
Shinohara H; Laboratory for Integrated Cellular Systems, RIKEN Center for Integrative Medical Sciences (IMS-RCAI), Tsurumi-ku, Yokohama, Kanagawa, 230-0045, Japan.
Nagashima T; Division of Cell Proliferation, ART, Graduate School of Medicine, Tohoku University, Sendai, Miyagi, 980-8575, Japan.
Cascalho MI; Department of Surgery, University of Michigan, Ann Arbor, MI, 48109, USA.; Department of Microbiology and Immunology, University of Michigan, Ann Arbor, MI, 48109, USA.
Kurosaki T; Laboratory for Lymphocyte Differentiation, RIKEN Center for Integrative Medical Sciences (IMS-RCAI), Tsurumi-ku, Yokohama, Kanagawa, 230-0045, Japan.; Laboratory for Lymphocyte Differentiation, Immunology Frontier Research Center, Osaka University, 3-1 Yamada-oka, Suita, Osaka, 565-0871, Japan.
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Źródło:
Genes to cells : devoted to molecular & cellular mechanisms [Genes Cells] 2016 Nov; Vol. 21 (11), pp. 1233-1243. Date of Electronic Publication: 2016 Oct 03.
Typ publikacji:
Journal Article
MeSH Terms:
Cell Survival*/genetics
B-Lymphocytes/*cytology
Immunoglobulin lambda-Chains/*metabolism
MAP Kinase Kinase Kinases/*physiology
Animals ; Apoptosis/genetics ; Cells, Cultured ; Gene Expression ; Genes, bcl-2 ; Mice ; NF-kappa B/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 1-20 z 38

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