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Wyświetlanie 1-6 z 6
Tytuł:
Time-resolved serial femtosecond crystallography reveals early structural changes in channelrhodopsin.
Autorzy:
Oda K; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan.
Nomura T; Graduate School of Life Science, University of Hyogo, Hyogo, Japan.
Nakane T; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan.
Yamashita K; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan.
Inoue K; Graduate School of Engineering, Nagoya Institute of Technology, Nagoya, Japan.
Ito S; Graduate School of Engineering, Nagoya Institute of Technology, Nagoya, Japan.
Vierock J; Institute of Biology, Experimental Biophysics, Humboldt-Universität zu Berlin, Berlin, Germany.
Hirata K; RIKEN SPring-8 Center, Hyogo, Japan.; Precursory Research for Embryonic Science and Technology (PRESTO), Japan Science and Technology Agency, Kawaguchi, Japan.
Maturana AD; Department of Bioengineering Sciences, Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya, Japan.
Katayama K; Graduate School of Engineering, Nagoya Institute of Technology, Nagoya, Japan.
Ikuta T; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan.
Ishigami I; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan.
Izume T; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan.
Umeda R; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan.
Eguma R; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan.
Oishi S; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan.
Kasuya G; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan.
Kato T; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan.
Kusakizako T; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan.
Shihoya W; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan.
Shimada H; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan.
Takatsuji T; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan.
Takemoto M; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan.
Taniguchi R; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan.
Tomita A; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan.
Nakamura R; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan.
Fukuda M; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan.
Miyauchi H; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan.
Lee Y; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan.
Nango E; RIKEN SPring-8 Center, Hyogo, Japan.; Department of Cell Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Tanaka R; RIKEN SPring-8 Center, Hyogo, Japan.; Department of Cell Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Tanaka T; RIKEN SPring-8 Center, Hyogo, Japan.; Department of Cell Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Sugahara M; RIKEN SPring-8 Center, Hyogo, Japan.
Kimura T; Department of Chemistry, Graduate School of Science, Kobe University, Kobe, Japan.
Shimamura T; Department of Cell Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Fujiwara T; Department of Cell Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Yamanaka Y; Department of Cell Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Owada S; RIKEN SPring-8 Center, Hyogo, Japan.; Japan Synchrotron Radiation Research Institute, Hyogo, Japan.
Joti Y; RIKEN SPring-8 Center, Hyogo, Japan.; Japan Synchrotron Radiation Research Institute, Hyogo, Japan.
Tono K; RIKEN SPring-8 Center, Hyogo, Japan.; Japan Synchrotron Radiation Research Institute, Hyogo, Japan.
Ishitani R; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan.
Hayashi S; Department of Chemistry, Graduate School of Science, Kyoto University, Kyoto, Japan.
Kandori H; Graduate School of Engineering, Nagoya Institute of Technology, Nagoya, Japan.
Hegemann P; Institute of Biology, Experimental Biophysics, Humboldt-Universität zu Berlin, Berlin, Germany.
Iwata S; RIKEN SPring-8 Center, Hyogo, Japan.; Department of Cell Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Kubo M; Graduate School of Life Science, University of Hyogo, Hyogo, Japan.
Nishizawa T; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan.; Precursory Research for Embryonic Science and Technology (PRESTO), Japan Science and Technology Agency, Kawaguchi, Japan.
Nureki O; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan.
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Źródło:
ELife [Elife] 2021 Mar 23; Vol. 10. Date of Electronic Publication: 2021 Mar 23.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Algal Proteins/*genetics
Channelrhodopsins/*genetics
Chlamydomonas reinhardtii/*genetics
Algal Proteins/chemistry ; Algal Proteins/metabolism ; Amino Acid Sequence ; Channelrhodopsins/chemistry ; Channelrhodopsins/metabolism ; Chlamydomonas reinhardtii/metabolism ; Crystallography ; Isomerism ; Protein Conformation ; Protein Structure, Secondary ; Sequence Alignment
Czasopismo naukowe
Tytuł:
Cryo-EM structure of the volume-regulated anion channel LRRC8D isoform identifies features important for substrate permeation.
Autorzy:
Nakamura R; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan.
Numata T; Department of Physiology, Graduate School of Medical Sciences, Fukuoka University, 7-45-1 Nanakuma, Johnan-ku, Fukuoka, Japan.
Kasuya G; Division of Integrative Physiology, Department of Physiology, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke-shi, Tochigi, Japan. .
Yokoyama T; Laboratory for Protein Functional and Structural Biology, RIKEN Center for Biosystems Dynamics Research, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama-shi, Kanagawa, Japan.
Nishizawa T; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan.
Kusakizako T; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan.
Kato T; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan.
Hagino T; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan.
Dohmae N; Biomolecular Characterization Unit, RIKEN Center for Sustainable Resource Science, 2-1 Hirosawa, Wako-shi, Saitama, Japan.
Inoue M; Laboratory of Cell Signaling, Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan.
Watanabe K; Laboratory of Cell Signaling, Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan.
Ichijo H; Laboratory of Cell Signaling, Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan.
Kikkawa M; Department of Cell Biology and Anatomy, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan.
Shirouzu M; Laboratory for Protein Functional and Structural Biology, RIKEN Center for Biosystems Dynamics Research, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama-shi, Kanagawa, Japan.
Jentsch TJ; Physiology and Pathology of Ion Transport, Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) and Max-Delbrück-Centrum für Molekulare Medizin, D-13125, Berlin, Germany.
Ishitani R; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan.
Okada Y; Department of Molecular Cell Physiology, Kyoto Prefectural University of Medicine, Kyoto, Japan. .; Department of Cell Physiology, National Institute for Physiological Sciences, Okazaki, Japan. .
Nureki O; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan. .
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Źródło:
Communications biology [Commun Biol] 2020 May 15; Vol. 3 (1), pp. 240. Date of Electronic Publication: 2020 May 15.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Signal Transduction*
Ion Transport/*physiology
Cryoelectron Microscopy ; Protein Domains ; Protein Isoforms/chemistry ; Protein Isoforms/ultrastructure ; Voltage-Dependent Anion Channels/chemistry ; Voltage-Dependent Anion Channels/ultrastructure
Czasopismo naukowe
Tytuł:
Structural insights into the competitive inhibition of the ATP-gated P2X receptor channel.
Autorzy:
Kasuya G; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 2-11-16 Yayoi, Bunkyo-ku, Tokyo, 113-0032, Japan.
Yamaura T; Laboratory for Drug Discovery, Pharmaceuticals Research Center, Asahi Kasei Pharma Corporation, 632-1 Mifuku, Izunokuni-shi, Shizuoka, 410-2321, Japan.
Ma XB; Department of Pharmacology and Chemical Biology, Institute of Medical Sciences, School of Medicine, Shanghai Jiao Tong University, 280 South Chongqing Road, Shanghai, 200025, China.
Nakamura R; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 2-11-16 Yayoi, Bunkyo-ku, Tokyo, 113-0032, Japan.
Takemoto M; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 2-11-16 Yayoi, Bunkyo-ku, Tokyo, 113-0032, Japan.
Nagumo H; Laboratory for Drug Discovery, Pharmaceuticals Research Center, Asahi Kasei Pharma Corporation, 632-1 Mifuku, Izunokuni-shi, Shizuoka, 410-2321, Japan.
Tanaka E; Laboratory for Drug Discovery, Pharmaceuticals Research Center, Asahi Kasei Pharma Corporation, 632-1 Mifuku, Izunokuni-shi, Shizuoka, 410-2321, Japan.
Dohmae N; Global Research Cluster, RIKEN, 2-1 Hirosawa, Wako-shi, Saitama, 351-0198, Japan.
Nakane T; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 2-11-16 Yayoi, Bunkyo-ku, Tokyo, 113-0032, Japan.
Yu Y; Department of Pharmacology and Chemical Biology, Institute of Medical Sciences, School of Medicine, Shanghai Jiao Tong University, 280 South Chongqing Road, Shanghai, 200025, China.
Ishitani R; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 2-11-16 Yayoi, Bunkyo-ku, Tokyo, 113-0032, Japan.
Matsuzaki O; Pharmaceuticals Research Center, Asahi Kasei Pharma Corporation, 632-1 Mifuku, Izunokuni-shi, Shizuoka, 410-2321, Japan. .
Hattori M; State Key Laboratory of Genetic Engineering, Collaborative Innovation Center of Genetics and Development, Department of Physiology and Biophysics, School of Life Sciences, Fudan University, 2005 Songhu Road, Yangpu District, Shanghai, 200438, China. .
Nureki O; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 2-11-16 Yayoi, Bunkyo-ku, Tokyo, 113-0032, Japan. .
Pokaż więcej
Źródło:
Nature communications [Nat Commun] 2017 Oct 12; Vol. 8 (1), pp. 876. Date of Electronic Publication: 2017 Oct 12.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Adenosine Triphosphate/*analogs & derivatives
Receptors, Purinergic P2X7/*chemistry
Adenosine Triphosphate/chemistry ; Animals ; Binding Sites ; Chickens ; Computational Biology ; Crystallography, X-Ray ; Models, Molecular ; Protein Structure, Tertiary ; Purinergic P2X Receptor Antagonists ; Structure-Activity Relationship
Czasopismo naukowe
    Wyświetlanie 1-6 z 6

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