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Wyszukujesz frazę ""Narcotic Antagonists"" wg kryterium: Temat


Tytuł:
Insights into the Current and Possible Future Use of Opioid Antagonists in Relation to Opioid-Induced Constipation and Dysbiosis.
Autorzy:
Essmat N; Department of Pharmacology and Pharmacotherapy, Faculty of Medicine, Semmelweis University, Nagyvárad tér 4, H-1445 Budapest, Hungary.; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Zagazig University, Zagazig 44519, Egypt.
Karádi DÁ; Department of Pharmacology and Pharmacotherapy, Faculty of Medicine, Semmelweis University, Nagyvárad tér 4, H-1445 Budapest, Hungary.
Zádor F; Department of Pharmacology and Pharmacotherapy, Faculty of Medicine, Semmelweis University, Nagyvárad tér 4, H-1445 Budapest, Hungary.
Király K; Department of Pharmacology and Pharmacotherapy, Faculty of Medicine, Semmelweis University, Nagyvárad tér 4, H-1445 Budapest, Hungary.
Fürst S; Department of Pharmacology and Pharmacotherapy, Faculty of Medicine, Semmelweis University, Nagyvárad tér 4, H-1445 Budapest, Hungary.
Al-Khrasani M; Department of Pharmacology and Pharmacotherapy, Faculty of Medicine, Semmelweis University, Nagyvárad tér 4, H-1445 Budapest, Hungary.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Nov 24; Vol. 28 (23). Date of Electronic Publication: 2023 Nov 24.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Narcotic Antagonists*/therapeutic use
Opioid-Induced Constipation*/drug therapy
Humans ; Analgesics, Opioid/adverse effects ; Constipation/chemically induced ; Constipation/drug therapy ; Constipation/metabolism ; Dysbiosis/chemically induced ; Dysbiosis/drug therapy ; Receptors, Opioid/metabolism
Czasopismo naukowe
Tytuł:
Optimization of Mass Spectrometry Imaging for Drug Metabolism and Distribution Studies in the Zebrafish Larvae Model: A Case Study with the Opioid Antagonist Naloxone.
Autorzy:
Park YM; Helmholtz Centre for Infection Research, Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Campus E8 1, Saarland University, 66123 Saarbrücken, Germany.; Environmental Safety Group, Korea Institute of Science and Technology (KIST) Europe, 66123 Saarbrücken, Germany.; Department of Pharmacy, Saarland University, 66123 Saarbrücken, Germany.
Meyer MR; Center for Molecular Signaling (PZMS), Institute of Experimental and Clinical Pharmacology and Toxicology, Department of Experimental and Clinical Toxicology, Saarland University, 66421 Homburg, Germany.
Müller R; Helmholtz Centre for Infection Research, Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Campus E8 1, Saarland University, 66123 Saarbrücken, Germany.; Department of Pharmacy, Saarland University, 66123 Saarbrücken, Germany.; German Center for Infection Research (DZIF), 38124 Braunschweig, Germany.
Herrmann J; Helmholtz Centre for Infection Research, Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Campus E8 1, Saarland University, 66123 Saarbrücken, Germany.; German Center for Infection Research (DZIF), 38124 Braunschweig, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jun 13; Vol. 24 (12). Date of Electronic Publication: 2023 Jun 13.
Typ publikacji:
Journal Article
MeSH Terms:
Narcotic Antagonists*/pharmacology
Zebrafish*
Animals ; Humans ; Naloxone/pharmacology ; Larva ; Pilot Projects ; Mass Spectrometry
Czasopismo naukowe
Tytuł:
Effects of a peripherally acting µ-opioid receptor antagonist for the prevention of recurrent acute pancreatitis: study protocol for an investigator-initiated, randomized, placebo-controlled, double-blind clinical trial (PAMORA-RAP trial).
Autorzy:
Cook ME; Department of Gastroenterology and Hepatology, Centre for Pancreatic Diseases and Mech-Sense, Aalborg University Hospital, Aalborg, Denmark. .; Department of Clinical Medicine, Aalborg University, Aalborg, Denmark. .
Knoph CS; Department of Gastroenterology and Hepatology, Centre for Pancreatic Diseases and Mech-Sense, Aalborg University Hospital, Aalborg, Denmark.; Department of Clinical Medicine, Aalborg University, Aalborg, Denmark.
Fjelsted CA; Department of Gastroenterology and Hepatology, Centre for Pancreatic Diseases and Mech-Sense, Aalborg University Hospital, Aalborg, Denmark.; Department of Clinical Medicine, Aalborg University, Aalborg, Denmark.
Frøkjær JB; Department of Clinical Medicine, Aalborg University, Aalborg, Denmark.; Department of Radiology, Aalborg University Hospital, Aalborg, Denmark.
Bilgrau AE; Department of Mathematical Sciences, Aalborg University, Aalborg, Denmark.
Novovic S; Copenhagen University Hospital Hvidovre, Hvidovre, Denmark.
Jørgensen MT; Department of Surgery, Odense Pancreas Centre (OPAC), HPB Section, Odense University Hospital, Odense, Denmark.
Mortensen MB; Department of Surgery, Odense Pancreas Centre (OPAC), HPB Section, Odense University Hospital, Odense, Denmark.
Nielsen LBJ; Digestive Disease Centre K, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark.
Hadi A; Digestive Disease Centre K, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark.
Berner-Hansen M; Digestive Disease Centre K, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark.
Rutkowski W; Department for Upper Abdominal Diseases, Karolinska University Hospital, Stockholm, Sweden.
Vujasinovic M; Department for Upper Abdominal Diseases, Karolinska University Hospital, Stockholm, Sweden.
Löhr M; Department for Upper Abdominal Diseases, Karolinska University Hospital, Stockholm, Sweden.
Drewes AM; Department of Gastroenterology and Hepatology, Centre for Pancreatic Diseases and Mech-Sense, Aalborg University Hospital, Aalborg, Denmark.; Department of Clinical Medicine, Aalborg University, Aalborg, Denmark.
Olesen SS; Department of Gastroenterology and Hepatology, Centre for Pancreatic Diseases and Mech-Sense, Aalborg University Hospital, Aalborg, Denmark. .; Department of Clinical Medicine, Aalborg University, Aalborg, Denmark. .
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Źródło:
Trials [Trials] 2023 May 01; Vol. 24 (1), pp. 301. Date of Electronic Publication: 2023 May 01.
Typ publikacji:
Clinical Trial Protocol; Journal Article
MeSH Terms:
Narcotic Antagonists*/adverse effects
Pancreatitis, Chronic*/drug therapy
Humans ; Quality of Life ; Acute Disease ; Analgesics, Opioid/adverse effects ; Disease Progression ; Treatment Outcome ; Double-Blind Method ; Randomized Controlled Trials as Topic
Czasopismo naukowe
Tytuł:
LY2444296, a κ-opioid receptor antagonist, selectively reduces alcohol drinking in male and female Wistar rats with a history of alcohol dependence.
Autorzy:
Flores-Ramirez FJ; Department of Molecular Medicine, The Scripps Research Institute, 10550 North Torrey Pines Road, SR-107, La Jolla, CA, 92037, USA. .
Illenberger JM; Department of Molecular Medicine, The Scripps Research Institute, 10550 North Torrey Pines Road, SR-107, La Jolla, CA, 92037, USA.
Pascasio G; Department of Molecular Medicine, The Scripps Research Institute, 10550 North Torrey Pines Road, SR-107, La Jolla, CA, 92037, USA.
Terenius L; Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden.
Martin-Fardon R; Department of Molecular Medicine, The Scripps Research Institute, 10550 North Torrey Pines Road, SR-107, La Jolla, CA, 92037, USA.
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Źródło:
Scientific reports [Sci Rep] 2024 Mar 09; Vol. 14 (1), pp. 5804. Date of Electronic Publication: 2024 Mar 09.
Typ publikacji:
Journal Article
MeSH Terms:
Alcoholism*/drug therapy
Alcoholism*/psychology
Substance Withdrawal Syndrome*/drug therapy
Substance Withdrawal Syndrome*/psychology
Humans ; Rats ; Male ; Female ; Animals ; Narcotic Antagonists/pharmacology ; Narcotic Antagonists/therapeutic use ; Rats, Wistar ; Receptors, Opioid, kappa ; Ethanol ; Alcohol Drinking ; Dynorphins ; Self Administration
Czasopismo naukowe
Tytuł:
Organize and mobilize for implementation effectiveness to improve overdose education and naloxone distribution from syringe services programs: a randomized controlled trial.
Autorzy:
Lambdin BH; RTI International, 2150 Shattuck Avenue, 8Th Floor, Berkeley, CA, 94704, USA. .; Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA, USA. .; Department of Global Health, University of Washington, Seattle, WA, USA. .
Bluthenthal RN; Keck Medicine, Department of Population and Public Health Sciences, University of Southern California, 1975 Zonal Ave, Los Angeles, CA, 90033, USA.
Garner BR; Department of Internal Medicine, College of Medicine, The Ohio State University, 370 W. 9Th Avenue, Columbus, OH, 43210, USA.
Wenger LD; RTI International, 2150 Shattuck Avenue, 8Th Floor, Berkeley, CA, 94704, USA.
Browne EN; RTI International, 2150 Shattuck Avenue, 8Th Floor, Berkeley, CA, 94704, USA.
Morris T; RTI International, 2150 Shattuck Avenue, 8Th Floor, Berkeley, CA, 94704, USA.
Ongais L; San Francisco AIDS Foundation, 1035 Market Street, 4Th Floor, San Francisco, CA, 94103, USA.
Megerian CE; RTI International, 2150 Shattuck Avenue, 8Th Floor, Berkeley, CA, 94704, USA.
Kral AH; RTI International, 2150 Shattuck Avenue, 8Th Floor, Berkeley, CA, 94704, USA.
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Źródło:
Implementation science : IS [Implement Sci] 2024 Feb 28; Vol. 19 (1), pp. 22. Date of Electronic Publication: 2024 Feb 28.
Typ publikacji:
Randomized Controlled Trial; Journal Article
MeSH Terms:
Opiate Overdose*/drug therapy
Drug Overdose*/drug therapy
Drug Overdose*/prevention & control
Opioid-Related Disorders*/drug therapy
Humans ; United States ; Naloxone/therapeutic use ; Health Education ; United States Department of Veterans Affairs ; Narcotic Antagonists/therapeutic use
Czasopismo naukowe
Tytuł:
The Role of Opioid Receptor Antagonists in Regulation of Blood Pressure and T-Cell Activation in Mice Selected for High Analgesia Induced by Swim Stress.
Autorzy:
Skiba D; Department of Experimental Genomics, Institute of Genetics and Animal Biotechnology, Polish Academy of Sciences, Postepu 36A Street, Jastrzebiec, 05-552 Magdalenka, Poland.
Jaskuła K; Department of Experimental Genomics, Institute of Genetics and Animal Biotechnology, Polish Academy of Sciences, Postepu 36A Street, Jastrzebiec, 05-552 Magdalenka, Poland.
Nawrocka A; Department of Experimental Genomics, Institute of Genetics and Animal Biotechnology, Polish Academy of Sciences, Postepu 36A Street, Jastrzebiec, 05-552 Magdalenka, Poland.
Poznański P; Department of Experimental Genomics, Institute of Genetics and Animal Biotechnology, Polish Academy of Sciences, Postepu 36A Street, Jastrzebiec, 05-552 Magdalenka, Poland.
Łazarczyk M; Department of Experimental Genomics, Institute of Genetics and Animal Biotechnology, Polish Academy of Sciences, Postepu 36A Street, Jastrzebiec, 05-552 Magdalenka, Poland.
Szymański Ł; Department of Experimental Genomics, Institute of Genetics and Animal Biotechnology, Polish Academy of Sciences, Postepu 36A Street, Jastrzebiec, 05-552 Magdalenka, Poland.
Żera T; Department of Experimental and Clinical Physiology, Center for Preclinical Research, Medical University of Warsaw, Banacha 1B Street, 02-097 Warsaw, Poland.
Sacharczuk M; Department of Experimental Genomics, Institute of Genetics and Animal Biotechnology, Polish Academy of Sciences, Postepu 36A Street, Jastrzebiec, 05-552 Magdalenka, Poland.; Department of Pharmacodynamics, Medical University of Warsaw, Zwirki i Wigury 81 Street, 02-091 Warsaw, Poland.
Cudnoch-Jędrzejewska A; Department of Experimental and Clinical Physiology, Center for Preclinical Research, Medical University of Warsaw, Banacha 1B Street, 02-097 Warsaw, Poland.
Gaciong Z; Department and Clinic of Internal Diseases, Hypertension and Angiology, Medical University of Warsaw, Banacha 1A Street, 02-097 Warsaw, Poland.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 23; Vol. 25 (5). Date of Electronic Publication: 2024 Feb 23.
Typ publikacji:
Journal Article
MeSH Terms:
Analgesia*
Hypertension*
Mice ; Animals ; Narcotic Antagonists/pharmacology ; Blood Pressure ; Receptors, Opioid, delta/metabolism ; Naloxone/pharmacology ; Receptors, Opioid, mu ; Pain ; Analgesics, Opioid/pharmacology ; Receptors, Opioid, kappa/metabolism
Czasopismo naukowe
Tytuł:
Feasibility of paying people who use drugs cash to distribute naloxone within their networks.
Autorzy:
Lewis NM; Berkshire Regional Planning Commission, Pittsfield, MA, USA. .
Smeltzer RP; Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Baker TJ; Clinical Addiction Research and Education Unit, Section of General Internal Medicine, Department of Medicine, Boston Medical Center, Boston, MA, USA.
Sahovey AC; Clinical Addiction Research and Education Unit, Section of General Internal Medicine, Department of Medicine, Boston Medical Center, Boston, MA, USA.
Baez J; ONESTOP Harm Reduction Center, Gloucester, MA, USA.
Hensel E; Tapestry Health, Holyoke, MA, USA.
Poole B; ONESTOP Harm Reduction Center, Gloucester, MA, USA.
Stewart C; Market Decisions Research, Portland, ME, USA.
Cogan AG; Clinical Addiction Research and Education Unit, Section of General Internal Medicine, Department of Medicine, Boston Medical Center, Boston, MA, USA.
Bullard M; Clinical Addiction Research and Education Unit, Section of General Internal Medicine, Department of Medicine, Boston Medical Center, Boston, MA, USA.
Taylor JL; Clinical Addiction Research and Education Unit, Section of General Internal Medicine, Department of Medicine, Boston Medical Center, Boston, MA, USA.; Grayken Center for Addiction, Boston Medical Center, Boston, MA, USA.; Boston University, Chobanian and Avedisian School of Medicine, Boston, MA, USA.
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Źródło:
Harm reduction journal [Harm Reduct J] 2024 Feb 16; Vol. 21 (1), pp. 42. Date of Electronic Publication: 2024 Feb 16.
Typ publikacji:
Journal Article
MeSH Terms:
Opioid-Related Disorders*/drug therapy
Opioid-Related Disorders*/complications
Drug Overdose*/drug therapy
Drug Overdose*/prevention & control
Drug Overdose*/epidemiology
Opiate Overdose*/drug therapy
Humans ; Naloxone/therapeutic use ; Narcotic Antagonists/therapeutic use ; Analgesics, Opioid/therapeutic use ; Pharmaceutical Preparations ; Feasibility Studies
Czasopismo naukowe
Tytuł:
Healthcare provider perspectives on emergency department-initiated buprenorphine/naloxone: a qualitative study.
Autorzy:
Badke K; Lower Mainland Pharmacy Services, Vancouver, BC, Canada. .; Pharmacy Department, Vancouver General Hospital, 899 W 12th avenue, Vancouver, BC, V5Z 1M9, Canada. .; Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada. .
Small SS; Department of Emergency Medicine, University of British Columbia, Vancouver, BC, Canada.; Centre for Clinical Epidemiology and Evaluation, Vancouver Coastal Health Research Institute, Vancouver, BC, Canada.
Pratt M; Social Work Department, Vancouver General Hospital, Vancouver, BC, Canada.
Lockington J; Department of Emergency Medicine, Vancouver General Hospital, Vancouver, BC, Canada.
Gurney L; Department of Emergency Medicine, Vancouver General Hospital, Vancouver, BC, Canada.; School of Nursing, University of British Columbia, Vancouver, BC, Canada.
Kestler A; Department of Emergency Medicine, University of British Columbia, Vancouver, BC, Canada.; Department of Emergency Medicine, Vancouver General Hospital, Vancouver, BC, Canada.; Department of Emergency Medicine, St. Paul's Hospital, Vancouver, BC, Canada.
Moe J; Department of Emergency Medicine, University of British Columbia, Vancouver, BC, Canada.; Department of Emergency Medicine, Vancouver General Hospital, Vancouver, BC, Canada.; Department of Emergency Medicine, BC Children's Hospital, Vancouver, BC, Canada.; BC Centre for Disease Control, Vancouver, BC, Canada.
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Źródło:
BMC health services research [BMC Health Serv Res] 2024 Feb 15; Vol. 24 (1), pp. 211. Date of Electronic Publication: 2024 Feb 15.
Typ publikacji:
Journal Article
MeSH Terms:
Opioid-Related Disorders*/epidemiology
Buprenorphine*/therapeutic use
Humans ; Narcotic Antagonists/therapeutic use ; Emergency Service, Hospital ; Health Personnel ; Naloxone/therapeutic use
Czasopismo naukowe
Tytuł:
An evaluation of first responders' intention to refer to post-overdose services following SHIELD training.
Autorzy:
Siddiqui ST; Missouri Institute of Mental Health, University of Missouri-St. Louis, 1 University Blvd, 206 Benton Hall, St. Louis, MO, 63121, USA. .
La Manna A; Missouri Institute of Mental Health, University of Missouri-St. Louis, 1 University Blvd, 206 Benton Hall, St. Louis, MO, 63121, USA.
Connors E; Missouri Institute of Mental Health, University of Missouri-St. Louis, 1 University Blvd, 206 Benton Hall, St. Louis, MO, 63121, USA.
Smith R; Missouri Institute of Mental Health, University of Missouri-St. Louis, 1 University Blvd, 206 Benton Hall, St. Louis, MO, 63121, USA.
Vance K; Missouri Institute of Mental Health, University of Missouri-St. Louis, 1 University Blvd, 206 Benton Hall, St. Louis, MO, 63121, USA.
Budesa Z; Missouri Institute of Mental Health, University of Missouri-St. Louis, 1 University Blvd, 206 Benton Hall, St. Louis, MO, 63121, USA.
Goulka J; SHIELD Training Initiative, Northeastern University, Boston, USA.
Beletsky L; SHIELD Training Initiative, Northeastern University, Boston, USA.
Wood CA; Missouri Institute of Mental Health, University of Missouri-St. Louis, 1 University Blvd, 206 Benton Hall, St. Louis, MO, 63121, USA.
Marotta P; Department of Social Work, Brown School, Washington University in St. Louis, St. Louis, USA.
Winograd RP; Missouri Institute of Mental Health, University of Missouri-St. Louis, 1 University Blvd, 206 Benton Hall, St. Louis, MO, 63121, USA.
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Źródło:
Harm reduction journal [Harm Reduct J] 2024 Feb 13; Vol. 21 (1), pp. 39. Date of Electronic Publication: 2024 Feb 13.
Typ publikacji:
Journal Article
MeSH Terms:
Emergency Responders*
Drug Overdose*/prevention & control
Drug Overdose*/drug therapy
Humans ; Narcotic Antagonists/therapeutic use ; Intention ; Naloxone/therapeutic use ; Analgesics, Opioid/therapeutic use
Czasopismo naukowe
Tytuł:
Factors associated with gaps in naloxone knowledge: evidence from a 2022 great plains survey.
Autorzy:
Cooper-Ohm S; Department of Economics, University of Iowa, Iowa City, USA.
Habecker P; Rural Drug Addiction Research Center, University of Nebraska-Lincoln, Oldfather Hall - 4th Floor, 660 N 12th Street, Lincoln, NE, 68588, USA. .
Humeniuk R; Honors Tutorial College, Ohio University, Athens, USA.
Bevins RA; Rural Drug Addiction Research Center, University of Nebraska-Lincoln, Oldfather Hall - 4th Floor, 660 N 12th Street, Lincoln, NE, 68588, USA.; Department of Psychology, University of Nebraska-Lincoln, Lincoln, USA.
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Źródło:
Harm reduction journal [Harm Reduct J] 2024 Feb 10; Vol. 21 (1), pp. 37. Date of Electronic Publication: 2024 Feb 10.
Typ publikacji:
Journal Article
MeSH Terms:
Opioid-Related Disorders*/drug therapy
Opioid-Related Disorders*/epidemiology
Drug Overdose*/drug therapy
Opiate Overdose*/drug therapy
Adult ; Humans ; Naloxone/therapeutic use ; Analgesics, Opioid/therapeutic use ; Heroin/therapeutic use ; Surveys and Questionnaires ; Narcotic Antagonists/therapeutic use
Czasopismo naukowe
Tytuł:
Comparison of Administration of 8-Milligram and 4-Milligram Intranasal Naloxone by Law Enforcement During Response to Suspected Opioid Overdose - New York, March 2022-August 2023.
Autorzy:
Payne ER
Stancliff S
Rowe K
Christie JA
Dailey MW
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Źródło:
MMWR. Morbidity and mortality weekly report [MMWR Morb Mortal Wkly Rep] 2024 Feb 08; Vol. 73 (5), pp. 110-113. Date of Electronic Publication: 2024 Feb 08.
Typ publikacji:
Journal Article
MeSH Terms:
Opiate Overdose*
Drug Overdose*/drug therapy
Drug Overdose*/epidemiology
Humans ; Naloxone/therapeutic use ; Analgesics, Opioid/therapeutic use ; Narcotic Antagonists/therapeutic use ; Law Enforcement ; New York/epidemiology
Czasopismo naukowe
Tytuł:
Factors associated with frequent buprenorphine / naloxone initiation in a national survey of Canadian emergency physicians.
Autorzy:
MacKinnon N; Department of Emergency Medicine, University of British Columbia, Vancouver, BC, Canada.; Department of Emergency Medicine, St. Paul's Hospital, Vancouver, British Columbia, Canada.
Lane D; Department of Emergency Medicine, University of British Columbia, Vancouver, BC, Canada.
Scheuermeyer F; Department of Emergency Medicine, University of British Columbia, Vancouver, BC, Canada.; Department of Emergency Medicine, St. Paul's Hospital, Vancouver, British Columbia, Canada.; Center for Health Evaluation and Outcome Sciences, Vancouver, British Columbia, Canada.
Kaczorowski J; Université de Montréal, Montreal, Quebec, Canada.
Dong K; Department of Emergency Medicine, University of Alberta, Edmonton, Alberta, Canada.
Orkin AM; Department of Family & Community Medicine, University of Toronto, Toronto, Ontario, Canada.
Daoust R; Université de Montréal, Montreal, Quebec, Canada.; Centre de Recherche de l'Hôpital Sacré-Coeur de Montréal, Montreal, Quebec, Canada.
Moe J; Department of Emergency Medicine, University of British Columbia, Vancouver, BC, Canada.; British Columbia Centre for Disease Control, Vancouver, British Columbia, Canada.
Andolfatto G; Department of Emergency Medicine, University of British Columbia, Vancouver, BC, Canada.
Klaiman M; Department of Medicine, University of Toronto, Toronto, Ontario, Canada.
Yan J; Division of Emergency Medicine, Schulich School of Medicine & Dentistry, Western University, London, Ontario, Canada.
Koh JJ; Department of Emergency Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Crowder K; Department of Emergency Medicine, University of Calgary, Calgary, Alberta, Canada.
Atkinson P; Department of Emergency Medicine, Dalhousie University, St. John, New Brunswick, Canada.
Savage D; Division of Clinical Sciences, Northern Ontario School of Medicine, Thunder Bay, Ontario, Canada.
Stempien J; Department of Emergency Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Besserer F; Department of Emergency Medicine, University of British Columbia, Prince George, British Columbia, Canada.
Wale J; Department of Emergency Medicine, University of British Columbia, Victoria, British Columbia, Canada.
Kestler A; Department of Emergency Medicine, University of British Columbia, Vancouver, BC, Canada.; Department of Emergency Medicine, St. Paul's Hospital, Vancouver, British Columbia, Canada.; Center for Health Evaluation and Outcome Sciences, Vancouver, British Columbia, Canada.; British Columbia Centre on Substance Use, Vancouver, British Columbia, Canada.
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Źródło:
PloS one [PLoS One] 2024 Feb 05; Vol. 19 (2), pp. e0297084. Date of Electronic Publication: 2024 Feb 05 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Buprenorphine*/therapeutic use
Opioid-Related Disorders*/drug therapy
Opioid-Related Disorders*/epidemiology
Opioid-Related Disorders*/complications
Humans ; Narcotic Antagonists/therapeutic use ; Canada/epidemiology ; Buprenorphine, Naloxone Drug Combination/therapeutic use ; Emergency Service, Hospital ; Cognition ; Naloxone/therapeutic use
Czasopismo naukowe
Tytuł:
Inhibitory Effects of a Novel μ-Opioid Receptor Nonpeptide Antagonist, UD-030, on Morphine-Induced Conditioned Place Preference.
Autorzy:
Ide S; Addictive Substance Project, Tokyo Metropolitan Institute of Medical Science, Tokyo 156-8506, Japan.
Iwase N; UBE Corporation, Yamaguchi 755-8633, Japan.
Arai K; UBE Corporation, Yamaguchi 755-8633, Japan.
Kojima M; UBE Corporation, Yamaguchi 755-8633, Japan.
Ushiyama S; UBE Corporation, Yamaguchi 755-8633, Japan.
Taniko K; Sanwa Kagaku Kenkyusho Co., Ltd., Aichi 461-8631, Japan.
Ikeda K; Addictive Substance Project, Tokyo Metropolitan Institute of Medical Science, Tokyo 156-8506, Japan.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Feb 08; Vol. 24 (4). Date of Electronic Publication: 2023 Feb 08.
Typ publikacji:
Journal Article
MeSH Terms:
Narcotic Antagonists*/pharmacology
Opioid-Related Disorders*
Mice ; Humans ; Animals ; Morphine/pharmacology ; Naltrexone/pharmacology ; Analgesics, Opioid/pharmacology ; Receptors, Opioid, delta/metabolism ; Mice, Inbred C57BL ; Receptors, Opioid, mu/metabolism
Czasopismo naukowe
Tytuł:
Treatment of dissociative symptoms with opioid antagonists: a systematic review.
Autorzy:
Escamilla I; TXP Research Group. Department of Medicine and Surgery, Universidad Cardenal Herrera-CEU, CEU Universities, Castellón de la Plana, Spain.; Consorcio Hospitalario Provincial Castellón, Castellón de la Plana, Spain.
Juan N; TXP Research Group. Department of Medicine and Surgery, Universidad Cardenal Herrera-CEU, CEU Universities, Castellón de la Plana, Spain.; Consorcio Hospitalario Provincial Castellón, Castellón de la Plana, Spain.
Peñalva C; TXP Research Group. Department of Medicine and Surgery, Universidad Cardenal Herrera-CEU, CEU Universities, Castellón de la Plana, Spain.; Consorcio Hospitalario Provincial Castellón, Castellón de la Plana, Spain.
Sánchez-Llorens M; Buñol Mental Health Unit, Hospital Manises, Valencia, Spain.
Renau J; TXP Research Group. Department of Medicine and Surgery, Universidad Cardenal Herrera-CEU, CEU Universities, Castellón de la Plana, Spain.; Consorcio Hospitalario Provincial Castellón, Castellón de la Plana, Spain.
Benito A; TXP Research Group. Department of Medicine and Surgery, Universidad Cardenal Herrera-CEU, CEU Universities, Castellón de la Plana, Spain.; Torrent Mental Health Unit, Hospital General Universitario Valencia, Valencia, Spain.
Haro G; TXP Research Group. Department of Medicine and Surgery, Universidad Cardenal Herrera-CEU, CEU Universities, Castellón de la Plana, Spain.; Dual Disorder Program, Consorcio Hospitalario Provincial Castellón, Castellón de la Plana, Spain.
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Źródło:
European journal of psychotraumatology [Eur J Psychotraumatol] 2023; Vol. 14 (2), pp. 2265184. Date of Electronic Publication: 2023 Oct 20.
Typ publikacji:
Systematic Review; Meta-Analysis; Journal Article; Review
MeSH Terms:
Narcotic Antagonists*/therapeutic use
Naltrexone*/therapeutic use
Humans ; Naloxone/therapeutic use ; Dissociative Disorders/drug therapy
Czasopismo naukowe
Tytuł:
Metabolic clearance of select opioids and opioid antagonists using hepatic spheroids and recombinant cytochrome P450 enzymes.
Autorzy:
Tuet WY; Pharmaceutical Sciences Department, US Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, Maryland, USA.
Pierce SA; Pharmaceutical Sciences Department, US Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, Maryland, USA.
Conroy M; Pharmaceutical Sciences Department, US Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, Maryland, USA.
Vignola JN; Pharmaceutical Sciences Department, US Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, Maryland, USA.
Tressler J; Pharmaceutical Sciences Department, US Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, Maryland, USA.
diTargiani RC; Pharmaceutical Sciences Department, US Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, Maryland, USA.
McCranor BJ; Pharmaceutical Sciences Department, US Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, Maryland, USA.
Wong B; Pharmaceutical Sciences Department, US Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, Maryland, USA.
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Źródło:
Pharmacology research & perspectives [Pharmacol Res Perspect] 2022 Oct; Vol. 10 (5), pp. e01000.
Typ publikacji:
Journal Article; Review; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Analgesics, Opioid*/metabolism
Analgesics, Opioid*/pharmacology
Narcotic Antagonists*/metabolism
Narcotic Antagonists*/pharmacology
Cytochrome P-450 Enzyme System/metabolism ; Fentanyl/metabolism ; Fentanyl/pharmacology ; Humans ; Microsomes, Liver/metabolism ; Spheroids, Cellular
Czasopismo naukowe
Tytuł:
Naldemedine is associated with earlier defecation in critically ill patients with opioid-induced constipation: A retrospective, single-center cohort study.
Autorzy:
Nishiyama S; Department of Anesthesiology and Critical Care Medicine, Jichi Medical University, Saitama Medical Center, Omiya, Saitama, Japan.
Uchino S; Department of Anesthesiology and Critical Care Medicine, Jichi Medical University, Saitama Medical Center, Omiya, Saitama, Japan.
Sasabuchi Y; Data Science Center, Jichi Medical University, Shimotsuke, Tochigi, Japan.
Masuyama T; Department of Anesthesiology and Critical Care Medicine, Jichi Medical University, Saitama Medical Center, Omiya, Saitama, Japan.
Lefor AK; Department of Surgery, Jichi Medical University, Shimotsuke, Tochigi, Japan.
Sanui M; Department of Anesthesiology and Critical Care Medicine, Jichi Medical University, Saitama Medical Center, Omiya, Saitama, Japan.
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Źródło:
PloS one [PLoS One] 2024 Jan 03; Vol. 19 (1), pp. e0295952. Date of Electronic Publication: 2024 Jan 03 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Analgesics, Opioid*/therapeutic use
Opioid-Induced Constipation*/drug therapy
Humans ; Retrospective Studies ; Narcotic Antagonists/pharmacology ; Defecation ; Cohort Studies ; Critical Illness ; Constipation/chemically induced ; Constipation/drug therapy ; Naltrexone/adverse effects
Czasopismo naukowe
Tytuł:
Chronic Voluntary Morphine Intake Is Associated with Changes in Brain Structures Involved in Drug Dependence in a Rat Model of Polydrug Use.
Autorzy:
Quintanilla ME; Molecular and Clinical Pharmacology Program, Institute of Biomedical Science, Faculty of Medicine, Universidad de Chile, Santiago 7610658, Chile.
Morales P; Molecular and Clinical Pharmacology Program, Institute of Biomedical Science, Faculty of Medicine, Universidad de Chile, Santiago 7610658, Chile.; Department of Neuroscience, Faculty of Medicine, Universidad de Chile, Santiago 7610658, Chile.; Research Center for the Development of Novel Therapeutic Alternatives for Alcohol Use Disorders, Santiago 7610658, Chile.
Santapau D; Center for Regenerative Medicine, Faculty of Medicine Clínica Alemana-Universidad del Desarrollo, Santiago 7610658, Chile.
Ávila A; Center for Regenerative Medicine, Faculty of Medicine Clínica Alemana-Universidad del Desarrollo, Santiago 7610658, Chile.
Ponce C; Department of Neuroscience, Faculty of Medicine, Universidad de Chile, Santiago 7610658, Chile.
Berrios-Cárcamo P; Center for Regenerative Medicine, Faculty of Medicine Clínica Alemana-Universidad del Desarrollo, Santiago 7610658, Chile.
Olivares B; Center for Medical Chemistry, Faculty of Medicine Clínica Alemana-Universidad del Desarrollo, Santiago 7610658, Chile.
Gallardo J; Center for Regenerative Medicine, Faculty of Medicine Clínica Alemana-Universidad del Desarrollo, Santiago 7610658, Chile.
Ezquer M; Center for Regenerative Medicine, Faculty of Medicine Clínica Alemana-Universidad del Desarrollo, Santiago 7610658, Chile.
Herrera-Marschitz M; Molecular and Clinical Pharmacology Program, Institute of Biomedical Science, Faculty of Medicine, Universidad de Chile, Santiago 7610658, Chile.; Department of Neuroscience, Faculty of Medicine, Universidad de Chile, Santiago 7610658, Chile.
Israel Y; Molecular and Clinical Pharmacology Program, Institute of Biomedical Science, Faculty of Medicine, Universidad de Chile, Santiago 7610658, Chile.
Ezquer F; Research Center for the Development of Novel Therapeutic Alternatives for Alcohol Use Disorders, Santiago 7610658, Chile.; Center for Regenerative Medicine, Faculty of Medicine Clínica Alemana-Universidad del Desarrollo, Santiago 7610658, Chile.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Dec 03; Vol. 24 (23). Date of Electronic Publication: 2023 Dec 03.
Typ publikacji:
Journal Article
MeSH Terms:
Morphine Dependence*
Substance-Related Disorders*/drug therapy
Humans ; Rats ; Animals ; Morphine/adverse effects ; Analgesics, Opioid/pharmacology ; Rats, Wistar ; Naloxone/pharmacology ; Brain ; Ethanol/pharmacology ; Narcotic Antagonists/pharmacology
Czasopismo naukowe
Tytuł:
Examining the benefit of a higher maintenance dose of extended-release buprenorphine in opioid-injecting participants treated for opioid use disorder.
Autorzy:
Greenwald MK; Department of Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, Detroit, MI, USA. .
Wiest KL; Boulder Care, Portland, OR, USA.
Haight BR; Indivior, Inc., North Chesterfield, VA, USA.
Laffont CM; Indivior, Inc., North Chesterfield, VA, USA.
Zhao Y; Indivior, Inc., North Chesterfield, VA, USA.
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Źródło:
Harm reduction journal [Harm Reduct J] 2023 Dec 02; Vol. 20 (1), pp. 173. Date of Electronic Publication: 2023 Dec 02.
Typ publikacji:
Randomized Controlled Trial; Journal Article
MeSH Terms:
Buprenorphine*/therapeutic use
Opioid-Related Disorders*/drug therapy
Opioid-Related Disorders*/epidemiology
Adult ; Humans ; Analgesics, Opioid/therapeutic use ; Narcotic Antagonists/therapeutic use ; Treatment Outcome ; Delayed-Action Preparations/therapeutic use
Czasopismo naukowe
Tytuł:
A Guide to Expanding the Use of Buprenorphine Beyond Standard Initiations for Opioid Use Disorder.
Autorzy:
Miller JC; Psychiatry Residency Spokane, Providence Sacred Heart Medical Center and Children's Hospital, 101 W Eighth Ave, Spokane, WA, 99204, USA.
Brooks MA; Psychiatry Residency Spokane, Providence Sacred Heart Medical Center and Children's Hospital, 101 W Eighth Ave, Spokane, WA, 99204, USA.
Wurzel KE; Psychiatry Residency Spokane, Providence Sacred Heart Medical Center and Children's Hospital, 101 W Eighth Ave, Spokane, WA, 99204, USA.
Cox EJ; Providence Research Network, Renton, WA, USA.
Wurzel JF 3rd; Psychiatry Residency Spokane, Providence Sacred Heart Medical Center and Children's Hospital, 101 W Eighth Ave, Spokane, WA, 99204, USA. .
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Źródło:
Drugs in R&D [Drugs R D] 2023 Dec; Vol. 23 (4), pp. 339-362. Date of Electronic Publication: 2023 Nov 08.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Buprenorphine*/therapeutic use
Opioid-Related Disorders*/drug therapy
Pregnancy ; Female ; Adolescent ; Child ; Humans ; Narcotic Antagonists/therapeutic use ; Opiate Substitution Treatment/methods ; Analgesics, Opioid/adverse effects
Czasopismo naukowe
Tytuł:
Bystander preference for naloxone products: a field experiment.
Autorzy:
Marks KR; Department of Behavioral Science, College of Medicine, University of Kentucky, Lexington, KY, USA. .; Department for Behavioral Health, Developmental and Intellectual Disabilities, Cabinet for Health and Family Services, 275 E. Main Street, Frankfort, KY, 40621, USA. .
Oyler DR; Department of Pharmacy Practice and Science, College of Pharmacy, University of Kentucky, Lexington, KY, USA.
Strickland JC; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Jaggers J; Kentucky Pharmacy Education and Research Foundation, Frankfort, KY, USA.
Roberts MF; Substance Use Priority Research Area, University of Kentucky, Lexington, KY, USA.
Miracle DK; Department of Pharmacy Practice and Science, College of Pharmacy, University of Kentucky, Lexington, KY, USA.
Barnes C; Kentucky Department for Public, Health Division of Public Health Protection & Safety, Frankfort, KY, USA.
Lei F; Department of Biostatistics, College of Public Health, University of Kentucky, Lexington, KY, USA.
Smith A; Department of Pharmacy Practice and Science, College of Pharmacy, University of Kentucky, Lexington, KY, USA.
Mackin E; Department of Pharmacy Practice and Science, College of Pharmacy, University of Kentucky, Lexington, KY, USA.
Martin MC; Kentucky Pharmacy Education and Research Foundation, Frankfort, KY, USA.
Freeman PR; Department of Pharmacy Practice and Science, College of Pharmacy, University of Kentucky, Lexington, KY, USA.
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Źródło:
Harm reduction journal [Harm Reduct J] 2023 Nov 28; Vol. 20 (1), pp. 171. Date of Electronic Publication: 2023 Nov 28.
Typ publikacji:
Journal Article
MeSH Terms:
Naloxone*/therapeutic use
Drug Overdose*/drug therapy
Drug Overdose*/prevention & control
Humans ; Narcotic Antagonists/therapeutic use ; Nasal Sprays ; Analgesics, Opioid/therapeutic use ; Administration, Intranasal
Czasopismo naukowe

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