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Tytuł :
Azithromycin Downregulates Gene Expression of IL-1β and Pathways Involving TMPRSS2 and TMPRSS11D Required by SARS-CoV-2.
Autorzy :
Renteria AE; Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, Quebec, Canada.; Centre Hospitalier de l'Université de Montréal (CHUM), Montréal, Quebec, Canada.
Mfuna Endam L; Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, Quebec, Canada.
Adam D; Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, Quebec, Canada.; Université de Montréal, Montréal, Quebec, Canada.
Filali-Mouhim A; Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, Quebec, Canada.
Maniakas A; Centre intégré universitaire de service de santé et sociaux (CIUSSS) de l'Est-de-l'île-de-Montréal associé à l'Université de Montréal, Montréal, Quebec, Canada.; McGill University, Montreal, Quebec, Canada.
Rousseau S; McGill University, Montreal, Quebec, Canada.; Research Institute of McGill University Healthcare Centre (MUHC), Montréal, Quebec, Canada and.
Brochiero E; Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, Quebec, Canada.; Université de Montréal, Montréal, Quebec, Canada.
Gallo S; Azienda Socio-Sanitaria Territoriale (ASST) dei Sette Laghi e Università dell'Insubria, Varese, Italy.
Desrosiers M; Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, Quebec, Canada.; Centre Hospitalier de l'Université de Montréal (CHUM), Montréal, Quebec, Canada.
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Źródło :
American journal of respiratory cell and molecular biology [Am J Respir Cell Mol Biol] 2020 Nov; Vol. 63 (5), pp. 707-709.
Typ publikacji :
Letter
MeSH Terms :
Anti-Inflammatory Agents/*pharmacology
Azithromycin/*pharmacology
Coronavirus Infections/*drug therapy
Interleukin-1beta/*metabolism
Membrane Proteins/*metabolism
Nasal Mucosa/*drug effects
Pneumonia, Viral/*drug therapy
Serine Endopeptidases/*metabolism
Serine Proteases/*metabolism
Betacoronavirus/pathogenicity ; Cells, Cultured ; Chronic Disease ; Coronavirus Infections/immunology ; Coronavirus Infections/metabolism ; Coronavirus Infections/virology ; Down-Regulation ; Host-Pathogen Interactions ; Humans ; Interleukin-1beta/genetics ; Male ; Membrane Proteins/genetics ; Nasal Mucosa/immunology ; Nasal Mucosa/metabolism ; Pandemics ; Pilot Projects ; Pneumonia, Viral/immunology ; Pneumonia, Viral/metabolism ; Pneumonia, Viral/virology ; Rhinitis/drug therapy ; Rhinitis/immunology ; Rhinitis/metabolism ; Serine Endopeptidases/genetics ; Serine Proteases/genetics ; Signal Transduction ; Sinusitis/drug therapy ; Sinusitis/immunology ; Sinusitis/metabolism
SCR Disease Name :
COVID-19
Opinia redakcyjna
Tytuł :
Neutrophilic inflammation in the respiratory mucosa predisposes to RSV infection.
Autorzy :
Habibi MS; National Heart and Lung Institute, Imperial College London, London, UK.
Thwaites RS; National Heart and Lung Institute, Imperial College London, London, UK.
Chang M; Merck & Co., Inc., Kenilworth, NJ, USA.
Jozwik A; National Heart and Lung Institute, Imperial College London, London, UK.
Paras A; National Heart and Lung Institute, Imperial College London, London, UK.
Kirsebom F; National Heart and Lung Institute, Imperial College London, London, UK.
Varese A; National Heart and Lung Institute, Imperial College London, London, UK.
Owen A; National Heart and Lung Institute, Imperial College London, London, UK.
Cuthbertson L; National Heart and Lung Institute, Imperial College London, London, UK.
James P; National Heart and Lung Institute, Imperial College London, London, UK.
Tunstall T; National Heart and Lung Institute, Imperial College London, London, UK.
Nickle D; Genetics & Pharmacogenomics, Department of Translational Medicine, Merck & Co., Inc., Boston, MA, USA.
Hansel TT; National Heart and Lung Institute, Imperial College London, London, UK.
Moffatt MF; National Heart and Lung Institute, Imperial College London, London, UK.
Johansson C; National Heart and Lung Institute, Imperial College London, London, UK. .
Chiu C; Department of Infectious Disease, Imperial College London, London, UK. .
Openshaw PJM; National Heart and Lung Institute, Imperial College London, London, UK. .
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Źródło :
Science (New York, N.Y.) [Science] 2020 Oct 09; Vol. 370 (6513).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Neutrophil Activation*
Respiratory Syncytial Viruses*
Nasal Mucosa/*immunology
Nasal Mucosa/*virology
Neutrophils/*immunology
Respiratory Syncytial Virus Infections/*immunology
Adolescent ; Adult ; Animals ; CD4 Lymphocyte Count ; CD4-Positive T-Lymphocytes/immunology ; CD8-Positive T-Lymphocytes/immunology ; Chemokine CXCL1/pharmacology ; Humans ; Inflammation/immunology ; Inflammation/virology ; Interleukin-17/immunology ; Mice ; Mice, Inbred C57BL ; Middle Aged ; Nasal Mucosa/pathology ; Neutrophils/drug effects ; Respiratory Syncytial Virus Infections/pathology ; Tumor Necrosis Factor-alpha/immunology ; Young Adult
Czasopismo naukowe
Tytuł :
Involvement of nasal trigeminal function in human stereo smelling.
Autorzy :
Croy I; Department of Psychotherapy and Psychosomatic Medicine, Medizinische Fakultät Carl Gustav Carus, Technische Universität Dresden, 01307 Dresden, Germany.
Hummel T; Smell & Taste Clinic, Department of Otorhinolaryngology, Medizinische Fakultät Carl Gustav Carus, Technische Universität Dresden, 01307 Dresden, Germany .
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Oct 20; Vol. 117 (42), pp. 25979. Date of Electronic Publication: 2020 Oct 06.
Typ publikacji :
Letter; Comment
MeSH Terms :
Nasal Mucosa*
Smell*
Humans
Opinia redakcyjna
Tytuł :
Reply to Croy and Hummel: Stereo smelling without involvement of nasal trigeminal function.
Autorzy :
Wu Y; State Key Laboratory of Brain and Cognitive Science, Institute of Psychology, Chinese Academy of Sciences, 100101 Beijing, China.; Department of Psychology, University of Chinese Academy of Sciences, 100049 Beijing, China.
Ye Y; State Key Laboratory of Brain and Cognitive Science, Institute of Psychology, Chinese Academy of Sciences, 100101 Beijing, China.; Department of Psychology, University of Chinese Academy of Sciences, 100049 Beijing, China.
Zhou W; State Key Laboratory of Brain and Cognitive Science, Institute of Psychology, Chinese Academy of Sciences, 100101 Beijing, China; .; Department of Psychology, University of Chinese Academy of Sciences, 100049 Beijing, China.; Chinese Academy of Sciences Center for Excellence in Brain Science and Intelligence Technology, Institute of Psychology, Chinese Academy of Sciences, 100101 Beijing, China.
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Oct 20; Vol. 117 (42), pp. 25980-25981. Date of Electronic Publication: 2020 Oct 06.
Typ publikacji :
Letter; Comment
MeSH Terms :
Nasal Mucosa*
Smell*
Humans
Opinia redakcyjna
Tytuł :
Urban particulate matter regulates tight junction proteins by inducing oxidative stress via the Akt signal pathway in human nasal epithelial cells.
Autorzy :
Lee DC; Department of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea; Department of Otorhinolaryngology-Head and Neck Surgery, Daejeon St. Mary's Hospital, Daeheung-dong, Jung-gu, Daejeon, Republic of Korea. Electronic address: .
Choi H; Clinical Research Institute, Daejeon St. Mary's Hospital, Daeheung-dong, Jung-gu, Daejeon, Republic of Korea. Electronic address: .
Oh JM; Clinical Research Institute, Daejeon St. Mary's Hospital, Daeheung-dong, Jung-gu, Daejeon, Republic of Korea. Electronic address: .
Lee J; Department of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea; Department of Otorhinolaryngology-Head and Neck Surgery, Seoul St. Mary's Hospital, 222, Banpo-daero, Seocho-gu, Seoul, Republic of Korea. Electronic address: .
Lee J; Department of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea; Department of Otorhinolaryngology-Head and Neck Surgery, Daejeon St. Mary's Hospital, Daeheung-dong, Jung-gu, Daejeon, Republic of Korea. Electronic address: .
Lee HY; Division of Pulmonary, Allergy and Critical Care Medicine, Department of Internal Medicine, The Catholic University of Korea, Seoul, Republic of Korea. Electronic address: .
Kang JY; Division of Pulmonary, Allergy and Critical Care Medicine, Department of Internal Medicine, The Catholic University of Korea, Seoul, Republic of Korea. Electronic address: .
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Źródło :
Toxicology letters [Toxicol Lett] 2020 Oct 15; Vol. 333, pp. 33-41. Date of Electronic Publication: 2020 Jul 17.
Typ publikacji :
Journal Article
MeSH Terms :
Air Pollutants/*toxicity
Epithelial Cells/*drug effects
Gene Expression Regulation/*drug effects
Nasal Mucosa/*drug effects
Oxidative Stress/*drug effects
Particulate Matter/*toxicity
Proto-Oncogene Proteins c-akt/*metabolism
Tight Junction Proteins/*metabolism
Acetylcysteine/pharmacology ; Cell Survival/drug effects ; Cells, Cultured ; Cytokines/genetics ; Cytokines/metabolism ; Epithelial Cells/metabolism ; Female ; Humans ; Male ; Middle Aged ; Nasal Mucosa/metabolism ; Oxidative Stress/genetics ; Signal Transduction ; Tight Junction Proteins/genetics ; Tight Junctions/drug effects ; Tight Junctions/metabolism ; Turbinates/drug effects ; Turbinates/metabolism ; Urbanization
Czasopismo naukowe
Tytuł :
Type 2 and interferon inflammation regulate SARS-CoV-2 entry factor expression in the airway epithelium.
Autorzy :
Sajuthi SP; Center for Genes, Environment, and Health, National Jewish Health, Denver, CO, USA.
DeFord P; Center for Genes, Environment, and Health, National Jewish Health, Denver, CO, USA.
Li Y; Center for Genes, Environment, and Health, National Jewish Health, Denver, CO, USA.
Jackson ND; Center for Genes, Environment, and Health, National Jewish Health, Denver, CO, USA.
Montgomery MT; Center for Genes, Environment, and Health, National Jewish Health, Denver, CO, USA.
Everman JL; Center for Genes, Environment, and Health, National Jewish Health, Denver, CO, USA.
Rios CL; Center for Genes, Environment, and Health, National Jewish Health, Denver, CO, USA.
Pruesse E; Center for Genes, Environment, and Health, National Jewish Health, Denver, CO, USA.
Nolin JD; Center for Genes, Environment, and Health, National Jewish Health, Denver, CO, USA.
Plender EG; Center for Genes, Environment, and Health, National Jewish Health, Denver, CO, USA.
Wechsler ME; Department of Medicine, National Jewish Health, Denver, CO, USA.
Mak ACY; Department of Medicine, University of California San Francisco, San Francisco, CA, USA.
Eng C; Department of Medicine, University of California San Francisco, San Francisco, CA, USA.
Salazar S; Department of Medicine, University of California San Francisco, San Francisco, CA, USA.
Medina V; Centro de Neumología Pediátrica, San Juan, Puerto Rico.
Wohlford EM; Department of Medicine, University of California San Francisco, San Francisco, CA, USA.; Division of Pediatric Allergy and Immunology, University of California San Francisco, San Francisco, CA, USA.
Huntsman S; Department of Medicine, University of California San Francisco, San Francisco, CA, USA.
Nickerson DA; Department of Genome Sciences, University of Washington, Seattle, WA, USA.; Northwest Genomics Center, Seattle, WA, USA.; Brotman Baty Institute, Seattle, WA, USA.
Germer S; New York Genome Center, New York City, NY, USA.
Zody MC; New York Genome Center, New York City, NY, USA.
Abecasis G; Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA.
Kang HM; Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA.
Rice KM; Department of Biostatistics, University of Washington, Seattle, WA, USA.
Kumar R; Department of Pediatrics, Ann and Robert H. Lurie Children's Hospital of Chicago, Northwestern University, Chicago, IL, USA.
Oh S; Department of Medicine, University of California San Francisco, San Francisco, CA, USA.
Rodriguez-Santana J; Centro de Neumología Pediátrica, San Juan, Puerto Rico.
Burchard EG; Department of Medicine, University of California San Francisco, San Francisco, CA, USA.; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA.
Seibold MA; Center for Genes, Environment, and Health, National Jewish Health, Denver, CO, USA. .; Department of Pediatrics, National Jewish Health, Denver, CO, USA. .; Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado-AMC, Aurora, CO, USA. .
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Źródło :
Nature communications [Nat Commun] 2020 Oct 12; Vol. 11 (1), pp. 5139. Date of Electronic Publication: 2020 Oct 12.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Betacoronavirus/*physiology
Coronavirus Infections/*virology
Interferons/*metabolism
Interleukin-13/*metabolism
Nasal Mucosa/*pathology
Peptidyl-Dipeptidase A/*genetics
Pneumonia, Viral/*virology
Serine Endopeptidases/*genetics
Child ; Coronavirus Infections/metabolism ; Coronavirus Infections/pathology ; Epithelial Cells/metabolism ; Gene Expression Profiling ; Gene Expression Regulation ; Genetic Variation ; Host-Pathogen Interactions ; Humans ; Inflammation ; Middle Aged ; Nasal Mucosa/metabolism ; Pandemics ; Peptidyl-Dipeptidase A/metabolism ; Pneumonia, Viral/metabolism ; Pneumonia, Viral/pathology ; Serine Endopeptidases/metabolism ; Virus Internalization
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Adhesion of Staphylococcus aureus to epithelial cells: an in vitro approach to study interactions within the nasal microbiota.
Autorzy :
Ménard G; Univ Rennes, CHU Rennes, Inserm BRM UMR 1230, F-35000 Rennes, France.
Bonnaure-Mallet M; Univ Rennes, CHU Rennes, Inserm-Inra NuMeCan, F-35000 Rennes, France.
Donnio PY; Univ Rennes, CHU Rennes, Inserm BRM UMR 1230, F-35000 Rennes, France.
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Źródło :
Journal of medical microbiology [J Med Microbiol] 2020 Oct; Vol. 69 (10), pp. 1253-1261. Date of Electronic Publication: 2020 Sep 10.
Typ publikacji :
Journal Article
MeSH Terms :
Bacterial Adhesion/*physiology
Nasal Mucosa/*metabolism
Staphylococcus aureus/*metabolism
Adult ; Bacteria ; Carrier State/microbiology ; Epithelial Cells/metabolism ; Epithelial Cells/microbiology ; Female ; Humans ; Male ; Microbiota ; Nasal Cavity/microbiology ; Nasal Mucosa/microbiology ; Nose/microbiology ; Staphylococcal Infections/microbiology ; Staphylococcus aureus/pathogenicity
Czasopismo naukowe
Tytuł :
[Preparation of Cangyi nanoemulsion in situ gel and drug release mechanism of nasal mucosa in vitro].
Autorzy :
Jian-Shuang C; Henan University of Chinese Medicine Zhengzhou 450046, China.
Hao C; Henan University of Chinese Medicine Zhengzhou 450046, China.
Cui-Shan XU; Henan University of Chinese Medicine Zhengzhou 450046, China.
Jie Y; Henan University of Chinese Medicine Zhengzhou 450046, China.
Yong-Yan J; Henan University of Chinese Medicine Zhengzhou 450046, China Henan Research Center for Special Processing Technology of Chinese Medicine Zhengzhou 450046, China.
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Źródło :
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica [Zhongguo Zhong Yao Za Zhi] 2020 Sep; Vol. 45 (17), pp. 4211-4220.
Typ publikacji :
Journal Article
MeSH Terms :
Nasal Mucosa*/metabolism
Poloxamer*
Drug Liberation ; Emulsions/metabolism ; Gels ; Temperature ; Viscosity
Czasopismo naukowe
Tytuł :
As Plain as the Nose on Your Face: The Case for A Nasal (Mucosal) Route of Vaccine Administration for Covid-19 Disease Prevention.
Autorzy :
Travis CR; Immugen Pharma LLC, South Miami, FL, United States.
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Źródło :
Frontiers in immunology [Front Immunol] 2020 Sep 30; Vol. 11, pp. 591897. Date of Electronic Publication: 2020 Sep 30 (Print Publication: 2020).
Typ publikacji :
Journal Article
MeSH Terms :
Administration, Intranasal/*methods
Betacoronavirus/*immunology
Coronavirus Infections/*prevention & control
Nasal Mucosa/*immunology
Pandemics/*prevention & control
Pneumonia, Viral/*prevention & control
Viral Vaccines/*administration & dosage
Adenoids/cytology ; Adenoids/immunology ; Antibodies, Viral/immunology ; Coronavirus Infections/immunology ; Humans ; Immunity, Mucosal/immunology ; Immunoglobulin A/immunology ; Immunoglobulin G/immunology ; Mouth Mucosa/cytology ; Mouth Mucosa/immunology ; Nasal Mucosa/cytology ; Palatine Tonsil/cytology ; Palatine Tonsil/immunology ; Viral Vaccines/immunology
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
A Single-Cell RNA Expression Map of Human Coronavirus Entry Factors.
Autorzy :
Singh M; Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853, USA. Electronic address: .
Bansal V; Biomedical Data Science and Machine Learning Group, German Center for Neurodegenerative Diseases, Tübingen 72076, Germany; Clinical Neuroscience, Max Planck Institute of Experimental Medicine, Göttingen 37075, Germany. Electronic address: .
Feschotte C; Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853, USA. Electronic address: .
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Źródło :
Cell reports [Cell Rep] 2020 Sep 22; Vol. 32 (12), pp. 108175. Date of Electronic Publication: 2020 Sep 03.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Virus Internalization*
Coronavirus Infections/*pathology
Nasal Mucosa/*metabolism
Pneumonia, Viral/*pathology
Receptors, Virus/*genetics
Viral Tropism/*genetics
A549 Cells ; Animals ; Betacoronavirus/growth & development ; Cell Line ; Chlorocebus aethiops ; Enterocytes/metabolism ; Gene Expression Profiling ; Goblet Cells/metabolism ; HEK293 Cells ; Humans ; Kidney Tubules, Proximal/cytology ; Kidney Tubules, Proximal/metabolism ; Nasal Mucosa/virology ; Pandemics ; Peptidyl-Dipeptidase A/genetics ; Peptidyl-Dipeptidase A/metabolism ; Serine Endopeptidases/genetics ; Serine Endopeptidases/metabolism ; Single-Cell Analysis ; Vero Cells
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Enhancement of ciliary beat amplitude by carbocisteine in ciliated human nasal epithelial cells.
Autorzy :
Inui TA; Department of Molecular Cell Physiology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.; Department of Otolaryngology-Head and Neck Surgery, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Yasuda M; Department of Otolaryngology-Head and Neck Surgery, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Hirano S; Department of Otolaryngology-Head and Neck Surgery, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Ikeuchi Y; Department of Molecular Cell Physiology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Kogiso H; Department of Molecular Cell Physiology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Inui T; Research Laboratory for Epithelial Physiology, Research Organization of Science and Technology, BKC, Ritsumeikan University, Kusatsu, Japan.; Saisei Mirai Clinics, Moriguchi, Japan.
Marunaka Y; Department of Molecular Cell Physiology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.; Research Laboratory for Epithelial Physiology, Research Organization of Science and Technology, BKC, Ritsumeikan University, Kusatsu, Japan.; Research Institute for Clinical Physiology, Kyoto Industrial Health Association, Kyoto, Japan.
Nakahari T; Research Laboratory for Epithelial Physiology, Research Organization of Science and Technology, BKC, Ritsumeikan University, Kusatsu, Japan.
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Źródło :
The Laryngoscope [Laryngoscope] 2020 May; Vol. 130 (5), pp. E289-E297. Date of Electronic Publication: 2019 Jul 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Carbocysteine/*pharmacology
Cilia/*drug effects
Mucociliary Clearance/*drug effects
Nasal Mucosa/*diagnostic imaging
Sinusitis/*drug therapy
Cells, Cultured ; Cilia/metabolism ; Cilia/pathology ; Epithelial Cells/drug effects ; Humans ; Nasal Mucosa/metabolism ; Nasal Mucosa/pathology ; Signal Transduction ; Sinusitis/metabolism ; Sinusitis/pathology
Czasopismo naukowe
Tytuł :
Red-green-blue analysis of nasal mucosa discolouration in allergic rhinitis.
Autorzy :
Degirmenci N; Department of Otorhinolaryngology, Bezmialem Vakif University, Istanbul, Turkey.
Dogan R; Department of Otorhinolaryngology, Bezmialem Vakif University, Istanbul, Turkey.
Tugrul S; Department of Otorhinolaryngology, Bezmialem Vakif University, Istanbul, Turkey.
Senturk E; Department of Otorhinolaryngology, Bezmialem Vakif University, Istanbul, Turkey.
Toprak A; Department of Biostatistics and Medical Informatics, Bezmialem Vakif University, Istanbul, Turkey.
Ozturan O; Department of Otorhinolaryngology, Bezmialem Vakif University, Istanbul, Turkey.
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Źródło :
The Journal of laryngology and otology [J Laryngol Otol] 2020 Apr; Vol. 134 (4), pp. 332-337. Date of Electronic Publication: 2020 Apr 02.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Color/*standards
Endoscopy/*methods
Nasal Mucosa/*anatomy & histology
Photography/*instrumentation
Rhinitis, Allergic/*diagnosis
Adult ; Clinical Trials as Topic ; Female ; Humans ; Male ; Middle Aged ; Nasal Mucosa/pathology ; Nasal Septum/diagnostic imaging ; Rhinitis, Allergic/epidemiology ; Rhinitis, Allergic/pathology ; Sensitivity and Specificity ; Software ; Turbinates/diagnostic imaging
Czasopismo naukowe
Tytuł :
Immunohistochemical and Molecular Diagnosis of Mucocutaneous and Mucosal Leishmaniasis.
Autorzy :
Sánchez-Romero C; University of Campinas (UNICAMP), Piracicaba, Brazil.; Universidad de la República, Montevideo, Uruguay.
Júnior HM; State University of Montes Claros, Montes Claros, Minas Gerais, Brazil.
Matta VLRD; State University of São Paulo (USP), São Paulo, Brazil.
Freitas LM; Federal University of Juiz de Fora, Governador Valadares, Minas Gerais, Brazil.
Soares CM; State University of São Paulo (USP), São Paulo, Brazil.
Mariano FV; State University of São Paulo (USP), São Paulo, Brazil.
de Almeida OP; University of Campinas (UNICAMP), Piracicaba, Brazil.
Nascimento de Aquino S; Federal University of Juiz de Fora, Governador Valadares, Minas Gerais, Brazil.
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Źródło :
International journal of surgical pathology [Int J Surg Pathol] 2020 Apr; Vol. 28 (2), pp. 138-145. Date of Electronic Publication: 2019 Sep 29.
Typ publikacji :
Journal Article
MeSH Terms :
Leishmaniasis/*diagnosis
Leishmaniasis, Mucocutaneous/*diagnosis
Nasal Mucosa/*metabolism
Palate, Soft/*metabolism
Skin/*metabolism
Adult ; Aged ; Aged, 80 and over ; Female ; Humans ; Immunohistochemistry ; Leishmaniasis/genetics ; Leishmaniasis/metabolism ; Leishmaniasis, Mucocutaneous/genetics ; Leishmaniasis, Mucocutaneous/metabolism ; Male ; Middle Aged ; Nasal Mucosa/pathology ; Palate, Soft/pathology ; Skin/pathology ; Young Adult
Czasopismo naukowe
Tytuł :
Nasal Gene Expression of Angiotensin-Converting Enzyme 2 in Children and Adults.
Autorzy :
Bunyavanich S; Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, New York.
Do A; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York.
Vicencio A; Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, New York.
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Źródło :
JAMA [JAMA] 2020 Jun 16; Vol. 323 (23), pp. 2427-2429.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Gene Expression*
Nasal Mucosa*/virology
Peptidyl-Dipeptidase A/*genetics
Adolescent ; Adult ; Age Factors ; Asthma/epidemiology ; Betacoronavirus/physiology ; Child ; Child, Preschool ; Coronavirus Infections/virology ; Female ; Humans ; Linear Models ; Male ; Middle Aged ; Pandemics ; Pneumonia, Viral/virology ; Retrospective Studies ; Sex Factors ; Virus Internalization ; Young Adult
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues.
Autorzy :
Ziegler CGK; Program in Health Sciences & Technology, Harvard Medical School & Massachusetts Institute of Technology, Boston, MA 02115, USA; Institute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Harvard Graduate Program in Biophysics, Harvard University, Cambridge, MA 02138, USA.
Allon SJ; Institute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Nyquist SK; Institute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Program in Computational & Systems Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Computer Science & Artificial Intelligence Lab, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Mbano IM; Africa Health Research Institute, Durban, South Africa; School of Laboratory Medicine and Medical Sciences, College of Health Sciences, University of KwaZulu-Natal, Durban, South Africa.
Miao VN; Program in Health Sciences & Technology, Harvard Medical School & Massachusetts Institute of Technology, Boston, MA 02115, USA; Institute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Tzouanas CN; Program in Health Sciences & Technology, Harvard Medical School & Massachusetts Institute of Technology, Boston, MA 02115, USA; Institute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Cao Y; University of Massachusetts Medical School, Worcester, MA 01655, USA.
Yousif AS; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA.
Bals J; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA.
Hauser BM; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA; Department of Microbiology, Harvard Medical School, Boston, MA 02115, USA.
Feldman J; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA; Department of Microbiology, Harvard Medical School, Boston, MA 02115, USA; Program in Virology, Harvard Medical School, Boston, MA 02115, USA.
Muus C; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; John A. Paulson School of Engineering & Applied Sciences, Harvard University, Cambridge, MA 02138, USA.
Wadsworth MH 2nd; Institute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Kazer SW; Institute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Hughes TK; Program in Health Sciences & Technology, Harvard Medical School & Massachusetts Institute of Technology, Boston, MA 02115, USA; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Program in Immunology, Harvard Medical School, Boston, MA 02115, USA.
Doran B; Institute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Division of Pediatric Hematology/Oncology, Boston Children's Hospital, Boston, MA 02115, USA; Division of Gastroenterology, Hepatology, and Nutrition, Boston Children's Hospital, Boston, MA 02115, USA.
Gatter GJ; Institute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Vukovic M; Institute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Taliaferro F; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Division of Gastroenterology, Hepatology, and Nutrition, Boston Children's Hospital, Boston, MA 02115, USA.
Mead BE; Institute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Guo Z; University of Massachusetts Medical School, Worcester, MA 01655, USA.
Wang JP; University of Massachusetts Medical School, Worcester, MA 01655, USA.
Gras D; Aix-Marseille University, INSERM, INRA, C2VN, Marseille, France.
Plaisant M; Université Côte d'Azur, CNRS, IPMC, Sophia-Antipolis, France.
Ansari M; Comprehensive Pneumology Center & Institute of Lung Biology and Disease, Helmholtz Zentrum München, Munich, Germany; German Center for Lung Research, Munich, Germany; Institute of Computational Biology, Helmholtz Zentrum München, Munich, Germany.
Angelidis I; Comprehensive Pneumology Center & Institute of Lung Biology and Disease, Helmholtz Zentrum München, Munich, Germany; German Center for Lung Research, Munich, Germany.
Adler H; German Center for Lung Research, Munich, Germany; Research Unit Lung Repair and Regeneration, Helmholtz Zentrum München, Munich, Germany.
Sucre JMS; Division of Neonatology, Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Taylor CJ; Divison of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Lin B; Center for Regenerative Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.
Waghray A; Center for Regenerative Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.
Mitsialis V; Division of Gastroenterology, Hepatology, and Nutrition, Boston Children's Hospital, Boston, MA 02115, USA; Division of Gastroenterology, Brigham and Women's Hospital, Boston, MA 02115, USA.
Dwyer DF; Division of Allergy and Clinical Immunology, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.
Buchheit KM; Division of Allergy and Clinical Immunology, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.
Boyce JA; Division of Allergy and Clinical Immunology, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.
Barrett NA; Division of Allergy and Clinical Immunology, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.
Laidlaw TM; Division of Allergy and Clinical Immunology, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.
Carroll SL; University of California, Berkeley, CA 94720, USA.
Colonna L; University of Washington, Seattle, WA 98195, USA.
Tkachev V; Division of Pediatric Hematology/Oncology, Boston Children's Hospital, Boston, MA 02115, USA; Dana Farber Cancer Institute, Boston, MA 02115, USA; Harvard Medical School, Boston, MA 02115, USA.
Peterson CW; Stem Cell & Gene Therapy Program, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA; Department of Medicine, University of Washington, Seattle, WA 98195, USA.
Yu A; Division of Pediatric Hematology/Oncology, Boston Children's Hospital, Boston, MA 02115, USA; Division of Gastroenterology and Hepatology, Seattle Children's Hospital, Seattle, WA 98145, USA.
Zheng HB; University of Washington, Seattle, WA 98195, USA; Division of Gastroenterology and Hepatology, Seattle Children's Hospital, Seattle, WA 98145, USA.
Gideon HP; Department of Microbiology & Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA 15219, USA; Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.
Winchell CG; Department of Microbiology & Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA 15219, USA; Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA; Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.
Lin PL; Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA; UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA 15224, USA; Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, PA 15224, USA.
Bingle CD; Department of Infection, Immunity & Cardiovascular Disease, The Medical School and The Florey Institute for Host Pathogen Interactions, University of Sheffield, Sheffield, S10 2TN, UK.
Snapper SB; Division of Gastroenterology, Hepatology, and Nutrition, Boston Children's Hospital, Boston, MA 02115, USA; Division of Gastroenterology, Brigham and Women's Hospital, Boston, MA 02115, USA.
Kropski JA; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232, USA; Department of Cell and Developmental Biology, Vanderbilt University Medical Center, Nashville, TN 37240, USA; Department of Veterans Affairs Medical Center, Nashville, TN 37212, USA.
Theis FJ; Institute of Computational Biology, Helmholtz Zentrum München, Munich, Germany.
Schiller HB; Comprehensive Pneumology Center & Institute of Lung Biology and Disease, Helmholtz Zentrum München, Munich, Germany; German Center for Lung Research, Munich, Germany.
Zaragosi LE; Université Côte d'Azur, CNRS, IPMC, Sophia-Antipolis, France.
Barbry P; Université Côte d'Azur, CNRS, IPMC, Sophia-Antipolis, France.
Leslie A; Africa Health Research Institute, Durban, South Africa; School of Laboratory Medicine and Medical Sciences, College of Health Sciences, University of KwaZulu-Natal, Durban, South Africa; Department of Infection & Immunity, University College London, London, UK.
Kiem HP; Stem Cell & Gene Therapy Program, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA; Department of Medicine, University of Washington, Seattle, WA 98195, USA.
Flynn JL; Department of Microbiology & Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA 15219, USA; Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.
Fortune SM; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.
Berger B; Computer Science & Artificial Intelligence Lab, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Department of Mathematics, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Finberg RW; University of Massachusetts Medical School, Worcester, MA 01655, USA.
Kean LS; Division of Pediatric Hematology/Oncology, Boston Children's Hospital, Boston, MA 02115, USA; Dana Farber Cancer Institute, Boston, MA 02115, USA; Harvard Medical School, Boston, MA 02115, USA.
Garber M; University of Massachusetts Medical School, Worcester, MA 01655, USA.
Schmidt AG; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA; Department of Microbiology, Harvard Medical School, Boston, MA 02115, USA.
Lingwood D; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA.
Shalek AK; Program in Health Sciences & Technology, Harvard Medical School & Massachusetts Institute of Technology, Boston, MA 02115, USA; Institute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Harvard Graduate Program in Biophysics, Harvard University, Cambridge, MA 02138, USA; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Program in Computational & Systems Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Program in Immunology, Harvard Medical School, Boston, MA 02115, USA; Harvard Medical School, Boston, MA 02115, USA; Harvard Stem Cell Institute, Cambridge, MA 02138, USA. Electronic address: .
Ordovas-Montanes J; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Program in Immunology, Harvard Medical School, Boston, MA 02115, USA; Division of Gastroenterology, Hepatology, and Nutrition, Boston Children's Hospital, Boston, MA 02115, USA; Harvard Stem Cell Institute, Cambridge, MA 02138, USA. Electronic address: .
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Corporate Authors :
HCA Lung Biological Network. Electronic address:
HCA Lung Biological Network
Źródło :
Cell [Cell] 2020 May 28; Vol. 181 (5), pp. 1016-1035.e19. Date of Electronic Publication: 2020 Apr 27.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Alveolar Epithelial Cells/*metabolism
Enterocytes/*metabolism
Goblet Cells/*metabolism
Interferon Type I/*metabolism
Nasal Mucosa/*cytology
Peptidyl-Dipeptidase A/*genetics
Adolescent ; Alveolar Epithelial Cells/immunology ; Animals ; Betacoronavirus/physiology ; Cell Line ; Cells, Cultured ; Child ; Coronavirus Infections/virology ; Enterocytes/immunology ; Goblet Cells/immunology ; HIV Infections/immunology ; Humans ; Influenza, Human/immunology ; Interferon Type I/immunology ; Lung/cytology ; Lung/pathology ; Macaca mulatta ; Mice ; Mycobacterium tuberculosis ; Nasal Mucosa/immunology ; Pandemics ; Peptidyl-Dipeptidase A/metabolism ; Pneumonia, Viral/virology ; Receptors, Virus/genetics ; Serine Endopeptidases/metabolism ; Single-Cell Analysis ; Tuberculosis/immunology ; Up-Regulation
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Schneiderian membrane thickness variation following endodontic procedures: a retrospective cone beam computed tomography study.
Autorzy :
Van Den Munckhof T; Department of Oral Radiology, Academic Centre for Dentistry Amsterdam, ACTA, Gustav Mahlerlaan 3004, 1081, LA, Amsterdam, The Netherlands.
Patel S; Department of Endodontics, Faculty of Dentistry, Oral & Craniofacial Sciences, King's College London, Guy's Hospital, Tower Wing, Floor 22, London, SE1 9RT, UK.
Koller G; Department of Endodontics, Faculty of Dentistry, Oral & Craniofacial Sciences, King's College London, Guy's Hospital, Tower Wing, Floor 22, London, SE1 9RT, UK.
Berkhout E; Department of Oral Radiology, Academic Centre for Dentistry Amsterdam, ACTA, Gustav Mahlerlaan 3004, 1081, LA, Amsterdam, The Netherlands.
Mannocci F; Department of Endodontics, Faculty of Dentistry, Oral & Craniofacial Sciences, King's College London, Guy's Hospital, Tower Wing, Floor 22, London, SE1 9RT, UK.
Foschi F; Department of Endodontics, Faculty of Dentistry, Oral & Craniofacial Sciences, King's College London, Guy's Hospital, Tower Wing, Floor 22, London, SE1 9RT, UK. .; Department of Therapeutic Dentistry, Institute of Dentistry, I. M. Sechenov First Moscow State Medical University, 119146, Moscow, Russia. .
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Źródło :
BMC oral health [BMC Oral Health] 2020 May 06; Vol. 20 (1), pp. 133. Date of Electronic Publication: 2020 May 06.
Typ publikacji :
Journal Article
MeSH Terms :
Dental Pulp Capping*
Root Canal Therapy*
Cone-Beam Computed Tomography/*methods
Dental Pulp Cavity/*diagnostic imaging
Nasal Mucosa/*diagnostic imaging
Female ; Humans ; London ; Male ; Nasal Mucosa/anatomy & histology ; Retreatment ; Retrospective Studies
Czasopismo naukowe
Tytuł :
Piper Nigrum extract improves OVA-induced nasal epithelial barrier dysfunction via activating Nrf2/HO-1 signaling.
Autorzy :
Bui TT; Faculty of Biology and Environmental Science, University of Science and Education, The University of Danang, Danang 59000, Viet Nam.
Fan Y; Department of Anatomy, Jeonbuk National University Medical School, Jeonju, Jeonbuk 54896, Republic of Korea.
Piao CH; Department of Anatomy, Jeonbuk National University Medical School, Jeonju, Jeonbuk 54896, Republic of Korea.
Nguyen TV; Department of Anatomy, Jeonbuk National University Medical School, Jeonju, Jeonbuk 54896, Republic of Korea.
Shin DU; Research Division of Food Functionality, Korea Food Research Institute, Wanju-gun, Jeonbuk 55365, Republic of Korea; KFRI School, Korea University of Science and Technology, Daejeon 305-350, Republic of Korea.
Jung SY; Research Division of Food Functionality, Korea Food Research Institute, Wanju-gun, Jeonbuk 55365, Republic of Korea; KFRI School, Korea University of Science and Technology, Daejeon 305-350, Republic of Korea.
Hyeon E; Department of Anatomy, Jeonbuk National University Medical School, Jeonju, Jeonbuk 54896, Republic of Korea.
Song CH; Department of Anatomy, Jeonbuk National University Medical School, Jeonju, Jeonbuk 54896, Republic of Korea; Institute for Medical Sciences, Jeonbuk National University, Jeonju, Jeonbuk 54896, Republic of Korea.
Lee SY; Research Division of Food Functionality, Korea Food Research Institute, Wanju-gun, Jeonbuk 55365, Republic of Korea; KFRI School, Korea University of Science and Technology, Daejeon 305-350, Republic of Korea.
Shin HS; Research Division of Food Functionality, Korea Food Research Institute, Wanju-gun, Jeonbuk 55365, Republic of Korea; KFRI School, Korea University of Science and Technology, Daejeon 305-350, Republic of Korea.
Chai OH; Department of Anatomy, Jeonbuk National University Medical School, Jeonju, Jeonbuk 54896, Republic of Korea; Institute for Medical Sciences, Jeonbuk National University, Jeonju, Jeonbuk 54896, Republic of Korea; Biomedical Research Institute, Jeonbuk National University Hospital, Jeonju, Jeonbuk 54896 Republic of Korea. Electronic address: .
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Źródło :
Cellular immunology [Cell Immunol] 2020 May; Vol. 351, pp. 104035. Date of Electronic Publication: 2019 Dec 30.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Heme Oxygenase-1/*metabolism
Membrane Proteins/*metabolism
NF-E2-Related Factor 2/*metabolism
Nasal Mucosa/*drug effects
Plant Extracts/*pharmacology
Rhinitis, Allergic/*metabolism
Animals ; Anti-Inflammatory Agents/pharmacology ; Male ; Mice ; Mice, Inbred BALB C ; Nasal Mucosa/metabolism ; Ovalbumin/toxicity ; Piper nigrum ; Rhinitis, Allergic/chemically induced ; Signal Transduction/drug effects
Czasopismo naukowe
Tytuł :
Strong correlation between air-liquid interface cultures and in vivo transcriptomics of nasal brush biopsy.
Autorzy :
Ghosh B; Department of Environmental Health and Engineering, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.
Park B; Department of Environmental Health and Engineering, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.
Bhowmik D; Department of Biology, Johns Hopkins University, Baltimore, Maryland.
Nishida K; Department of Pulmonary and Critical Care Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland.
Lauver M; Department of Pulmonary and Critical Care Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland.
Putcha N; Department of Pulmonary and Critical Care Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland.
Gao P; Division of Allergy and Clinical Immunology, Johns Hopkins School of Medicine, Baltimore, Maryland.
Ramanathan M Jr; Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins School of Medicine, Baltimore, Maryland.
Hansel N; Department of Pulmonary and Critical Care Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland.
Biswal S; Department of Environmental Health and Engineering, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.
Sidhaye VK; Department of Environmental Health and Engineering, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.; Department of Pulmonary and Critical Care Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland.
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Źródło :
American journal of physiology. Lung cellular and molecular physiology [Am J Physiol Lung Cell Mol Physiol] 2020 May 01; Vol. 318 (5), pp. L1056-L1062. Date of Electronic Publication: 2020 Apr 01.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Transcriptome*
Nasal Mucosa/*metabolism
Pulmonary Disease, Chronic Obstructive/*genetics
Respiratory Mucosa/*metabolism
Aged ; Air ; Cigarette Smoking/adverse effects ; Culture Media/chemistry ; Female ; Gene Expression Profiling ; Humans ; Male ; Middle Aged ; Models, Biological ; Molecular Sequence Annotation ; Nasal Mucosa/pathology ; Primary Cell Culture ; Pulmonary Disease, Chronic Obstructive/etiology ; Pulmonary Disease, Chronic Obstructive/metabolism ; Pulmonary Disease, Chronic Obstructive/pathology ; Respiratory Mucosa/pathology ; Sequence Analysis, RNA ; Turbinates/metabolism ; Turbinates/pathology
Czasopismo naukowe
Tytuł :
Epithelial cell function and remodeling in nasal polyposis.
Autorzy :
Bankova LG; Division of Allergy and Clinical Immunology, Harvard Medical School and Brigham and Women's Hospital, Boston, Massachusetts.
Barrett NA; Division of Allergy and Clinical Immunology, Harvard Medical School and Brigham and Women's Hospital, Boston, Massachusetts. Electronic address: .
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Źródło :
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology [Ann Allergy Asthma Immunol] 2020 Apr; Vol. 124 (4), pp. 333-341. Date of Electronic Publication: 2020 Jan 30.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Airway Remodeling*
Nasal Mucosa/*pathology
Nasal Polyps/*pathology
Rhinitis/*pathology
Sinusitis/*pathology
Chronic Disease ; Humans ; Inflammation/immunology ; Inflammation/pathology ; Nasal Mucosa/immunology ; Nasal Polyps/immunology ; Rhinitis/immunology ; Sinusitis/immunology
Czasopismo naukowe
Tytuł :
Transcriptomic changes in the nasal epithelium associated with diesel engine exhaust exposure.
Autorzy :
Drizik E; Section of Computational Biomedicine, Department of Medicine, Boston University School of Medicine, Boston, MA, USA.
Corbett S; Bioinformatics Program, Boston University, Boston, MA, USA.
Zheng Y; Key Laboratory of Chemical Safety and Health, National Institute of Occupational, Health and Poison Control, Chinese Center for Disease Control and Prevention, Beijing, China. Electronic address: .
Vermeulen R; Institute for Risk Assessment Sciences, Utrecht University, Utrecht, the Netherlands.
Dai Y; Key Laboratory of Chemical Safety and Health, National Institute of Occupational, Health and Poison Control, Chinese Center for Disease Control and Prevention, Beijing, China.
Hu W; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA.
Ren D; Chaoyang Center for Disease Control and Prevention, Chaoyang, China.
Duan H; Key Laboratory of Chemical Safety and Health, National Institute of Occupational, Health and Poison Control, Chinese Center for Disease Control and Prevention, Beijing, China.
Niu Y; Key Laboratory of Chemical Safety and Health, National Institute of Occupational, Health and Poison Control, Chinese Center for Disease Control and Prevention, Beijing, China.
Xu J; Hong Kong University, Hong Kong, China.
Fu W; Chaoyang Center for Disease Control and Prevention, Chaoyang, China.
Meliefste K; Institute for Risk Assessment Sciences, Utrecht University, Utrecht, the Netherlands.
Zhou B; Key Laboratory of Chemical Safety and Health, National Institute of Occupational, Health and Poison Control, Chinese Center for Disease Control and Prevention, Beijing, China.
Zhang X; Section of Computational Biomedicine, Department of Medicine, Boston University School of Medicine, Boston, MA, USA.
Yang J; Chaoyang Center for Disease Control and Prevention, Chaoyang, China.
Bassig B; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA.
Liu H; Section of Computational Biomedicine, Department of Medicine, Boston University School of Medicine, Boston, MA, USA.
Ye M; Key Laboratory of Chemical Safety and Health, National Institute of Occupational, Health and Poison Control, Chinese Center for Disease Control and Prevention, Beijing, China.
Liu G; Section of Computational Biomedicine, Department of Medicine, Boston University School of Medicine, Boston, MA, USA.
Jia X; Key Laboratory of Chemical Safety and Health, National Institute of Occupational, Health and Poison Control, Chinese Center for Disease Control and Prevention, Beijing, China.
Meng T; Key Laboratory of Chemical Safety and Health, National Institute of Occupational, Health and Poison Control, Chinese Center for Disease Control and Prevention, Beijing, China.
Bin P; Key Laboratory of Chemical Safety and Health, National Institute of Occupational, Health and Poison Control, Chinese Center for Disease Control and Prevention, Beijing, China.
Zhang J; Nicholas School of the Environment and Duke Global Health Institute, Duke University, Durham, NC, USA; Global Health Research Center, Duke Kunshan University, Kunshan City, Jiangsu Province, China.
Silverman D; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA.
Spira A; Section of Computational Biomedicine, Department of Medicine, Boston University School of Medicine, Boston, MA, USA; Bioinformatics Program, Boston University, Boston, MA, USA; The Lung Cancer Initiative at Johnson & Johnson, Cambridge, MA, USA.
Rothman N; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA.
Lenburg ME; Section of Computational Biomedicine, Department of Medicine, Boston University School of Medicine, Boston, MA, USA; Bioinformatics Program, Boston University, Boston, MA, USA. Electronic address: .
Lan Q; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA.
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Źródło :
Environment international [Environ Int] 2020 Apr; Vol. 137, pp. 105506. Date of Electronic Publication: 2020 Feb 07.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Nasal Mucosa*/drug effects
Occupational Exposure*
Transcriptome*
Vehicle Emissions*/toxicity
Humans ; Leukocytes, Mononuclear
Czasopismo naukowe

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