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Tytuł:
Quantitative Assessment of Levonorgestrel Binding Partner Interplay and Drug-Drug Interactions Using Physiologically Based Pharmacokinetic Modeling.
Autorzy:
Cicali B; Center for Pharmacometrics and Systems Pharmacology, Department of Pharmaceutics, College of Pharmacy, University of Florida, Orlando, Florida, USA.
Lingineni K; Center for Pharmacometrics and Systems Pharmacology, Department of Pharmaceutics, College of Pharmacy, University of Florida, Orlando, Florida, USA.
Cristofoletti R; Center for Pharmacometrics and Systems Pharmacology, Department of Pharmaceutics, College of Pharmacy, University of Florida, Orlando, Florida, USA.
Wendl T; Bayer AG Pharmaceuticals, Leverkusen, Germany.
Hoechel J; Bayer AG Pharmaceuticals, Leverkusen, Germany.
Wiesinger H; Bayer AG Pharmaceuticals, Leverkusen, Germany.
Chaturvedula A; Department of Pharmacotherapy, System College of Pharmacy, University of Northern Texas Health Science Center, Fort Worth, Texas, USA.
Vozmediano V; Center for Pharmacometrics and Systems Pharmacology, Department of Pharmaceutics, College of Pharmacy, University of Florida, Orlando, Florida, USA.
Schmidt S; Center for Pharmacometrics and Systems Pharmacology, Department of Pharmaceutics, College of Pharmacy, University of Florida, Orlando, Florida, USA.
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Źródło:
CPT: pharmacometrics & systems pharmacology [CPT Pharmacometrics Syst Pharmacol] 2021 Jan; Vol. 10 (1), pp. 48-58. Date of Electronic Publication: 2020 Dec 13.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Models, Biological*
Contraceptives, Oral, Combined/*pharmacokinetics
Cytochrome P-450 CYP3A Inducers/*pharmacology
Cytochrome P-450 CYP3A Inhibitors/*pharmacology
Ethinyl Estradiol/*pharmacokinetics
Levonorgestrel/*pharmacokinetics
Obesity/*metabolism
Adult ; Alkynes/pharmacology ; Benzoxazines/pharmacology ; Body Mass Index ; Carbamazepine/pharmacology ; Clarithromycin/pharmacology ; Computer Simulation ; Cyclopropanes/pharmacology ; Drug Combinations ; Drug Interactions ; Female ; Humans ; Itraconazole/pharmacology ; Rifampin/pharmacology ; Sex Hormone-Binding Globulin/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
High-fat diet in a mouse insulin-resistant model induces widespread rewiring of the phosphotyrosine signaling network.
Autorzy:
Dittmann A; The David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Center for Precision Cancer Medicine, Massachusetts Institute of Technology, Cambridge, MA, USA.
Kennedy NJ; Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA, USA.
Soltero NL; The David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.
Morshed N; The David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Center for Precision Cancer Medicine, Massachusetts Institute of Technology, Cambridge, MA, USA.
Mana MD; The David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Broad Institute of Harvard and MIT, Cambridge, MA, USA.
Yilmaz ÖH; The David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Davis RJ; Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA, USA.; Howard Hughes Medical Institute, Worcester, MA, USA.
White FM; The David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Center for Precision Cancer Medicine, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
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Źródło:
Molecular systems biology [Mol Syst Biol] 2019 Aug; Vol. 15 (8), pp. e8849.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Protein Processing, Post-Translational*
Diabetes Mellitus, Type 2/*metabolism
Diet, High-Fat/*adverse effects
Liver/*drug effects
Obesity/*metabolism
Phosphotyrosine/*metabolism
Animals ; Cell Line, Tumor ; Diabetes Mellitus, Type 2/etiology ; Diabetes Mellitus, Type 2/genetics ; Diabetes Mellitus, Type 2/pathology ; Disease Models, Animal ; Fatty Acids/pharmacology ; Hepatocytes/drug effects ; Hepatocytes/metabolism ; Hepatocytes/pathology ; Liver/metabolism ; Liver/pathology ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Obesity/etiology ; Obesity/genetics ; Obesity/pathology ; Phosphorylation/drug effects ; Protein Kinase Inhibitors/pharmacology ; Proteomics/methods ; Rats ; Reactive Oxygen Species/agonists ; Reactive Oxygen Species/metabolism ; Signal Transduction ; src-Family Kinases/genetics ; src-Family Kinases/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Modeling of the Weight Status and Risk of Nonalcoholic Fatty Liver Disease in Elderly Individuals: The Potential Impact of the Disulfide Bond-Forming Oxidoreductase A-Like Protein (DsbA-L) Polymorphism on the Weight Status.
Autorzy:
Oniki K; Division of Pharmacology and Therapeutics, Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan.
Watanabe T; Department of Gastroenterology and Hepatology, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.
Kudo M; Division of Pharmacology and Therapeutics, Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan.
Izuka T; Division of Pharmacology and Therapeutics, Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan.
Ono T; Division of Pharmacology and Therapeutics, Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan.
Matsuda K; Division of Pharmacology and Therapeutics, Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan.
Sakamoto Y; Division of Pharmacology and Therapeutics, Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan.
Nagaoka K; Department of Gastroenterology and Hepatology, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.
Imafuku T; Department of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan.
Ishima Y; Department of Pharmacokinetics and Biopharmaceutics, Institute of Biomedical Sciences, Tokushima University, Tokushima, Japan.
Watanabe H; Department of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan.
Maruyama T; Department of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan.
Otake K; Japanese Red Cross Kumamoto Health Care Center, Kumamoto, Japan.
Ogata Y; Department of Gastroenterology and Hepatology, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.
Saruwatari J; Division of Pharmacology and Therapeutics, Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan.; Center for Clinical Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan.
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Źródło:
CPT: pharmacometrics & systems pharmacology [CPT Pharmacometrics Syst Pharmacol] 2018 Jun; Vol. 7 (6), pp. 384-393. Date of Electronic Publication: 2018 Mar 30.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Polymorphism, Single Nucleotide*
Glutathione Transferase/*genetics
Non-alcoholic Fatty Liver Disease/*epidemiology
Obesity/*epidemiology
Adiponectin/metabolism ; Aged ; Body Mass Index ; Body Weight ; Female ; Genetic Predisposition to Disease ; Genotype ; Humans ; Japan/epidemiology ; Longitudinal Studies ; Male ; Mass Screening ; Middle Aged ; Non-alcoholic Fatty Liver Disease/genetics ; Non-alcoholic Fatty Liver Disease/metabolism ; Nonlinear Dynamics ; Obesity/complications ; Obesity/genetics ; Obesity/metabolism ; Prevalence ; Retrospective Studies
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Obesity-related insulin resistance: implications for the surgical patient.
Autorzy:
Tewari N; Gastrointestinal Surgery, National Institute for Health Research, Nottingham Digestive Diseases Biomedical Research Unit, Nottingham University Hospitals, Queen's Medical Centre, Nottingham, UK.
Awad S; The East-Midlands Bariatric & Metabolic Institute (EMBMI), Royal Derby Hospital, Derby, UK.; School of Medicine, University of Nottingham, Queen's Medical Centre, Nottingham, UK.
Macdonald IA; School of Life Sciences, University of Nottingham, Queen's Medical Centre, Nottingham, UK.
Lobo DN; Gastrointestinal Surgery, National Institute for Health Research, Nottingham Digestive Diseases Biomedical Research Unit, Nottingham University Hospitals, Queen's Medical Centre, Nottingham, UK.; School of Medicine, University of Nottingham, Queen's Medical Centre, Nottingham, UK.
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Źródło:
International journal of obesity (2005) [Int J Obes (Lond)] 2015 Nov; Vol. 39 (11), pp. 1575-88. Date of Electronic Publication: 2015 Jun 01.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Insulin Resistance*/immunology
Anesthesia, General/*methods
Inflammation/*etiology
Obesity/*complications
Postoperative Complications/*etiology
Surgical Procedures, Operative/*methods
Anesthesia, General/adverse effects ; Humans ; Inflammation/immunology ; Intra-Abdominal Fat ; Obesity/immunology ; Obesity/surgery ; Postoperative Complications/immunology ; Risk Factors ; Surgical Procedures, Operative/adverse effects ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Longitudinal investigation of adenovirus 36 seropositivity and human obesity: the Cardiovascular Risk in Young Finns Study.
Autorzy:
Sabin MA; Murdoch Childrens Research Institute at The Royal Children's Hospital, Melbourne, Australia.; Department of Paediatrics, University of Melbourne, Melbourne, Australia.
Burgner D; Murdoch Childrens Research Institute at The Royal Children's Hospital, Melbourne, Australia.; Department of Paediatrics, University of Melbourne, Melbourne, Australia.; Department of Paediatrics, Monash University, Melbourne, Australia.
Atkinson RL; Obetech Obesity Research Center, Richmond, VA, USA.
Pei-Lun Lee Z; Obetech Obesity Research Center, Richmond, VA, USA.
Magnussen CG; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku University Hospital, Turku, Finland.; Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia.
Cheung M; Murdoch Childrens Research Institute at The Royal Children's Hospital, Melbourne, Australia.; Department of Paediatrics, University of Melbourne, Melbourne, Australia.
Kähönen M; Department of Clinical Physiology, University of Tampere and Tampere University Hospital, Tampere, Finland.
Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, University of Tampere School of Medicine, Tampere, Finland.
Jokinen E; Hospital for Children and Adolescents, University of Helsinki, Helsinki, Finland.
Laitinen T; Department of Clinical Physiology, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland.
Hutri-Kähönen N; Department of Pediatrics, University of Tampere and Tampere University Hospital, Tampere, Finland.
Viikari JS; Department of Medicine, University of Turku, Turku, Finland.; Division of Medicine, Turku University Hospital, Turku, Finland.
Juonala M; Murdoch Childrens Research Institute at The Royal Children's Hospital, Melbourne, Australia.; Department of Medicine, University of Turku, Turku, Finland.; Division of Medicine, Turku University Hospital, Turku, Finland.
Raitakari OT; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku University Hospital, Turku, Finland.; Division of Medicine, Turku University Hospital, Turku, Finland.; Department of Clinical Physiology and Nuclear Medicine, University of Turku, Turku, Finland.
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Źródło:
International journal of obesity (2005) [Int J Obes (Lond)] 2015 Nov; Vol. 39 (11), pp. 1644-50. Date of Electronic Publication: 2015 Jun 09.
Typ publikacji:
Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
MeSH Terms:
Adenoviridae/*isolation & purification
Adenoviridae Infections/*complications
Cardiovascular Diseases/*etiology
Obesity/*etiology
Adenoviridae Infections/physiopathology ; Adolescent ; Adult ; Cardiovascular Diseases/blood ; Cardiovascular Diseases/prevention & control ; Child ; Child, Preschool ; Cross-Sectional Studies ; Female ; Humans ; Longitudinal Studies ; Male ; Obesity/blood ; Obesity/physiopathology ; Risk Factors
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Fully-automated, high-throughput micro-computed tomography analysis of body composition enables therapeutic efficacy monitoring in preclinical models.
Autorzy:
Wyatt SK; Department of Biomedical Imaging, Genentech, Inc., South San Francisco, CA, USA.
Barck KH; Department of Biomedical Imaging, Genentech, Inc., South San Francisco, CA, USA.
Kates L; Department of Biomedical Imaging, Genentech, Inc., South San Francisco, CA, USA.
Zavala-Solorio J; Department of Biomedical Imaging, Genentech, Inc., South San Francisco, CA, USA.
Ross J; Department of Biomedical Imaging, Genentech, Inc., South San Francisco, CA, USA.
Kolumam G; Department of Biomedical Imaging, Genentech, Inc., South San Francisco, CA, USA.
Sonoda J; Department of Molecular Biology, Genentech, Inc., South San Francisco, CA, USA.
Carano RA; Department of Biomedical Imaging, Genentech, Inc., South San Francisco, CA, USA.
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Źródło:
International journal of obesity (2005) [Int J Obes (Lond)] 2015 Nov; Vol. 39 (11), pp. 1630-7. Date of Electronic Publication: 2015 Jun 15.
Typ publikacji:
Journal Article; Validation Study
MeSH Terms:
X-Ray Microtomography*
Adipose Tissue/*pathology
Obesity/*pathology
Adipose Tissue/diagnostic imaging ; Animals ; Body Composition ; Disease Models, Animal ; Image Interpretation, Computer-Assisted ; Male ; Mice ; Mice, Obese ; Reproducibility of Results ; Sensitivity and Specificity
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
A novel gene THSD7A is associated with obesity.
Autorzy:
Nizamuddin S; CSIR-Centre for Cellular and Molecular Biology, Hyderabad, India.
Govindaraj P; CSIR-Centre for Cellular and Molecular Biology, Hyderabad, India.
Saxena S; CSIR-Centre for Cellular and Molecular Biology, Hyderabad, India.
Kashyap M; CSIR-Centre for Cellular and Molecular Biology, Hyderabad, India.
Mishra A; CSIR-Centre for Cellular and Molecular Biology, Hyderabad, India.
Singh S; CSIR-Centre for Cellular and Molecular Biology, Hyderabad, India.
Rotti H; School of Life Sciences, Manipal University, Karnataka, India.
Raval R; School of Life Sciences, Manipal University, Karnataka, India.
Nayak J; Shri Dharmasthala Manjunatheshwara College of Ayurveda, Karnataka, India.
Bhat BK; Shri Dharmasthala Manjunatheshwara College of Ayurveda, Karnataka, India.
Prasanna BV; Shri Dharmasthala Manjunatheshwara College of Ayurveda, Karnataka, India.
Dhumal VR; Sinhgad College of Engineering, Maharashtra, India.
Bhale S; Sinhgad College of Engineering, Maharashtra, India.
Joshi KS; Sinhgad College of Engineering, Maharashtra, India.
Dedge AP; Sinhgad College of Engineering, Maharashtra, India.
Bharadwaj R; Foundation for Revitalization of Local Health Traditions, Karnataka, India.
Gangadharan GG; Foundation for Revitalization of Local Health Traditions, Karnataka, India.
Nair S; Department of Statistics, Manipal University, Karnataka, India.
Gopinath PM; School of Life Sciences, Manipal University, Karnataka, India.
Patwardhan B; Interdisciplinary School of Health Sciences, University of Pune, Maharashtra, India.
Kondaiah P; Department of Molecular Reproduction, Development and Genetics, Indian Institute of Science, Karnataka, India.
Satyamoorthy K; School of Life Sciences, Manipal University, Karnataka, India.
Valiathan MS; School of Life Sciences, Manipal University, Karnataka, India.
Thangaraj K; CSIR-Centre for Cellular and Molecular Biology, Hyderabad, India.
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Źródło:
International journal of obesity (2005) [Int J Obes (Lond)] 2015 Nov; Vol. 39 (11), pp. 1662-5. Date of Electronic Publication: 2015 Aug 04.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Polymorphism, Single Nucleotide*
Ethnicity/*genetics
Obesity/*ethnology
Obesity/*genetics
Thrombospondins/*genetics
White People/*genetics
Adult ; Body Mass Index ; Female ; Genetic Variation ; Genetics, Population ; Genome-Wide Association Study ; Humans ; India/epidemiology ; Linkage Disequilibrium ; Male ; Obesity/epidemiology ; Phenotype ; White People/statistics & numerical data
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Association between eating rate and obesity: a systematic review and meta-analysis.
Autorzy:
Ohkuma T; Center for Cohort Studies, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.; Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Hirakawa Y; Department of Environmental Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Nakamura U; Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Kiyohara Y; Center for Cohort Studies, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.; Department of Environmental Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Kitazono T; Center for Cohort Studies, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.; Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Ninomiya T; Center for Cohort Studies, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.; Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.; Department of Environmental Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
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Źródło:
International journal of obesity (2005) [Int J Obes (Lond)] 2015 Nov; Vol. 39 (11), pp. 1589-96. Date of Electronic Publication: 2015 May 25.
Typ publikacji:
Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't; Review; Systematic Review
MeSH Terms:
Feeding Behavior*/psychology
Obesity/*etiology
Body Mass Index ; Energy Metabolism ; Humans ; Obesity/prevention & control ; Obesity/psychology ; Risk Factors
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
The intake of high-fat diets induces the acquisition of brown adipocyte gene expression features in white adipose tissue.
Autorzy:
García-Ruiz E; Laboratory of Molecular Biology, Nutrition and Biotechnology, Universitat de les Illes Balears and CIBER de Fisiopatología de la Obesidad y Nutrición (CIBERobn), Palma de Mallorca, Spain.
Reynés B; Laboratory of Molecular Biology, Nutrition and Biotechnology, Universitat de les Illes Balears and CIBER de Fisiopatología de la Obesidad y Nutrición (CIBERobn), Palma de Mallorca, Spain.
Díaz-Rúa R; Laboratory of Molecular Biology, Nutrition and Biotechnology, Universitat de les Illes Balears and CIBER de Fisiopatología de la Obesidad y Nutrición (CIBERobn), Palma de Mallorca, Spain.
Ceresi E; Laboratory of Molecular Biology, Nutrition and Biotechnology, Universitat de les Illes Balears and CIBER de Fisiopatología de la Obesidad y Nutrición (CIBERobn), Palma de Mallorca, Spain.
Oliver P; Laboratory of Molecular Biology, Nutrition and Biotechnology, Universitat de les Illes Balears and CIBER de Fisiopatología de la Obesidad y Nutrición (CIBERobn), Palma de Mallorca, Spain.
Palou A; Laboratory of Molecular Biology, Nutrition and Biotechnology, Universitat de les Illes Balears and CIBER de Fisiopatología de la Obesidad y Nutrición (CIBERobn), Palma de Mallorca, Spain.
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Źródło:
International journal of obesity (2005) [Int J Obes (Lond)] 2015 Nov; Vol. 39 (11), pp. 1619-29. Date of Electronic Publication: 2015 Jun 11.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Adipocytes, Brown/*metabolism
Adipose Tissue, White/*metabolism
Leukocytes, Mononuclear/*metabolism
Obesity/*pathology
Animals ; Cell Differentiation ; Diet, High-Fat ; Disease Models, Animal ; Gene Expression Regulation ; Male ; Mitochondrial Proteins ; Rats ; Rats, Wistar ; Signal Transduction ; Thermogenesis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Effect of adipose tissue volume loss on circulating 25-hydroxyvitamin D levels: results from a 1-year lifestyle intervention in viscerally obese men.
Autorzy:
Gangloff A; Centre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec, Québec City, Québec, Canada.; Lipid Research Center, CHU de Québec Research Center, Québec City, Québec, Canada.
Bergeron J; Lipid Research Center, CHU de Québec Research Center, Québec City, Québec, Canada.
Pelletier-Beaumont E; Centre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec, Québec City, Québec, Canada.; Faculty of Medicine, Department of Kinesiology, Université Laval, Québec City, Québec, Canada.
Nazare JA; Centre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec, Québec City, Québec, Canada.; Centre Européen pour la Nutrition et la Santé (CENS), CarMeN Laboratory, Lyon, France.
Smith J; Centre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec, Québec City, Québec, Canada.
Borel AL; Centre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec, Québec City, Québec, Canada.; Endocrinology Department, University Hospital, Grenoble, France.; INSERM U1042, Grenoble, France.; University Grenoble Alpes, Grenoble, France.
Lemieux I; Centre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec, Québec City, Québec, Canada.
Tremblay A; Centre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec, Québec City, Québec, Canada.; Faculty of Medicine, Department of Kinesiology, Université Laval, Québec City, Québec, Canada.
Poirier P; Centre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec, Québec City, Québec, Canada.; Faculty of Pharmacy, Université Laval, Québec City, Québec, Canada.
Alméras N; Centre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec, Québec City, Québec, Canada.; Faculty of Medicine, Department of Kinesiology, Université Laval, Québec City, Québec, Canada.
Després JP; Centre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec, Québec City, Québec, Canada.; Faculty of Medicine, Department of Kinesiology, Université Laval, Québec City, Québec, Canada.
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Źródło:
International journal of obesity (2005) [Int J Obes (Lond)] 2015 Nov; Vol. 39 (11), pp. 1638-43. Date of Electronic Publication: 2015 Jun 22.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Caloric Restriction*
Exercise*
Risk Reduction Behavior*
Weight Loss*
Dyslipidemias/*blood
Obesity/*blood
Vitamin D/*analogs & derivatives
Adipose Tissue ; Adiposity ; Adult ; Biomarkers/blood ; Dyslipidemias/therapy ; Feeding Behavior ; Humans ; Male ; Men's Health ; Middle Aged ; Obesity/complications ; Obesity/prevention & control ; Quebec ; Reference Values ; Treatment Outcome ; Vitamin D/blood
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Job strain and risk of obesity: systematic review and meta-analysis of cohort studies.
Autorzy:
Kivimäki M; Department of Epidemiology and Public Health, University College London, London, UK.; Department of Public Health, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Singh-Manoux A; Department of Epidemiology and Public Health, University College London, London, UK.; Inserm, Centre for Research in Epidemiology and Population Health, Hôpital Paul Brousse, Villejuif, France.
Nyberg S; Finnish Institute of Occupational Health, Helsinki, Finland.
Jokela M; Institute of Behavioral Sciences, University of Helsinki, Helsinki, Finland.
Virtanen M; Finnish Institute of Occupational Health, Helsinki, Finland.
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Źródło:
International journal of obesity (2005) [Int J Obes (Lond)] 2015 Nov; Vol. 39 (11), pp. 1597-600. Date of Electronic Publication: 2015 Jun 04.
Typ publikacji:
Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't; Review; Systematic Review
MeSH Terms:
Weight Gain*
Cardiovascular Diseases/*prevention & control
Diabetes Mellitus, Type 2/*prevention & control
Employment/*psychology
Obesity/*etiology
Occupational Diseases/*psychology
Stress, Psychological/*complications
Body Mass Index ; Cardiovascular Diseases/etiology ; Cardiovascular Diseases/psychology ; Diabetes Mellitus, Type 2/etiology ; Diabetes Mellitus, Type 2/psychology ; Humans ; Obesity/physiopathology ; Obesity/psychology ; Stress, Psychological/physiopathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Hepatic denervation and dyslipidemia in obese Zucker (fa/fa) rats.
Autorzy:
Bruinstroop E; Department of Endocrinology and Metabolism, Academic Medical Center (AMC), University of Amsterdam, Amsterdam, The Netherlands.; Department of Hypothalamic Integration Mechanisms, Netherlands Institute for Neuroscience, An Institute of the Royal Netherlands Academy of Arts and Science, Amsterdam, The Netherlands.
Eliveld J; Department of Hypothalamic Integration Mechanisms, Netherlands Institute for Neuroscience, An Institute of the Royal Netherlands Academy of Arts and Science, Amsterdam, The Netherlands.
Foppen E; Department of Endocrinology and Metabolism, Academic Medical Center (AMC), University of Amsterdam, Amsterdam, The Netherlands.; Department of Hypothalamic Integration Mechanisms, Netherlands Institute for Neuroscience, An Institute of the Royal Netherlands Academy of Arts and Science, Amsterdam, The Netherlands.
Busker S; Department of Hypothalamic Integration Mechanisms, Netherlands Institute for Neuroscience, An Institute of the Royal Netherlands Academy of Arts and Science, Amsterdam, The Netherlands.
Ackermans MT; Department of Clinical Chemistry, Laboratory of Endocrinology, Academic Medical Center (AMC), University of Amsterdam, Amsterdam, The Netherlands.
Fliers E; Department of Endocrinology and Metabolism, Academic Medical Center (AMC), University of Amsterdam, Amsterdam, The Netherlands.
Kalsbeek A; Department of Endocrinology and Metabolism, Academic Medical Center (AMC), University of Amsterdam, Amsterdam, The Netherlands.; Department of Hypothalamic Integration Mechanisms, Netherlands Institute for Neuroscience, An Institute of the Royal Netherlands Academy of Arts and Science, Amsterdam, The Netherlands.
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Źródło:
International journal of obesity (2005) [Int J Obes (Lond)] 2015 Nov; Vol. 39 (11), pp. 1655-8. Date of Electronic Publication: 2015 Jul 02.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Dyslipidemias/*metabolism
Hypothalamus/*metabolism
Lipoproteins, VLDL/*metabolism
Liver/*innervation
Obesity/*pathology
Sympathetic Nervous System/*pathology
Triglycerides/*metabolism
Animals ; Denervation ; Disease Models, Animal ; Liver/metabolism ; Rats ; Rats, Zucker
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Cluster analysis of behavioural weight management strategies and associations with weight change in young women: a longitudinal analysis.
Autorzy:
Madigan CD; Department of Primary Care Clinical Sciences, School of Health and Population Sciences, University of Birmingham, Birmingham, UK.
Daley AJ; Department of Primary Care Clinical Sciences, School of Health and Population Sciences, University of Birmingham, Birmingham, UK.
Kabir E; School of Agricultural, Computational and Environmental Sciences, University of Southern Queensland, Darling Heights, Queensland, Australia.; School of Human Movement and Nutrition Sciences, University of Queensland, St Lucia, Queensland, Australia.
Aveyard P; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
Brown W; School of Human Movement and Nutrition Sciences, University of Queensland, St Lucia, Queensland, Australia.
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Źródło:
International journal of obesity (2005) [Int J Obes (Lond)] 2015 Nov; Vol. 39 (11), pp. 1601-6. Date of Electronic Publication: 2015 Jun 22.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Diet*
Exercise*
Health Behavior*
Obesity/*psychology
Australia/epidemiology ; Cluster Analysis ; Energy Intake ; Energy Metabolism ; Female ; Health Knowledge, Attitudes, Practice ; Humans ; Longitudinal Studies ; Obesity/prevention & control ; Patient Compliance ; Public Health ; Weight Gain ; Women's Health ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Intermuscular and perimuscular fat expansion in obesity correlates with skeletal muscle T cell and macrophage infiltration and insulin resistance.
Autorzy:
Khan IM; Interdepartmental Program in Translational Biology and Molecular Medicine, Baylor College of Medicine, Houston, TX, USA.; Division of Atherosclerosis and Vascular Medicine, Section of Cardiovascular Research, Department of Medicine, Baylor College of Medicine, Houston, TX, USA.
Perrard XY; Division of Atherosclerosis and Vascular Medicine, Section of Cardiovascular Research, Department of Medicine, Baylor College of Medicine, Houston, TX, USA.
Brunner G; Division of Atherosclerosis and Vascular Medicine, Section of Cardiovascular Research, Department of Medicine, Baylor College of Medicine, Houston, TX, USA.
Lui H; Division of Atherosclerosis and Vascular Medicine, Section of Cardiovascular Research, Department of Medicine, Baylor College of Medicine, Houston, TX, USA.
Sparks LM; Translational Research Institute for Metabolism and Diabetes, Florida Hospital, Orlando, FL, USA.
Smith SR; Translational Research Institute for Metabolism and Diabetes, Florida Hospital, Orlando, FL, USA.
Wang X; Department of Translational Imaging, Houston Methodist Research Institute, Houston, TX, USA.
Shi ZZ; Department of Translational Imaging, Houston Methodist Research Institute, Houston, TX, USA.
Lewis DE; Division of Infectious Diseases, Department of Internal Medicine, UT Health, Houston, TX, USA.
Wu H; Division of Atherosclerosis and Vascular Medicine, Section of Cardiovascular Research, Department of Medicine, Baylor College of Medicine, Houston, TX, USA.; Section of Leukocyte Biology, Children's Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.
Ballantyne CM; Division of Atherosclerosis and Vascular Medicine, Section of Cardiovascular Research, Department of Medicine, Baylor College of Medicine, Houston, TX, USA.; Section of Leukocyte Biology, Children's Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.; Center for Cardiovascular Disease Prevention, Methodist DeBakey Heart and Vascular Center, Houston, TX, USA.
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Źródło:
International journal of obesity (2005) [Int J Obes (Lond)] 2015 Nov; Vol. 39 (11), pp. 1607-18. Date of Electronic Publication: 2015 Jun 04.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Adipose Tissue/*pathology
CD4-Positive T-Lymphocytes/*metabolism
CD8-Positive T-Lymphocytes/*metabolism
Inflammation/*pathology
Muscle, Skeletal/*pathology
Obesity/*pathology
3T3-L1 Cells ; Animals ; Diet, High-Fat ; Disease Models, Animal ; Insulin Resistance ; Male ; Mice ; Mice, Inbred C57BL ; T-Lymphocyte Subsets ; X-Ray Microtomography
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Job strain and risk of obesity: should we discriminate mental and physical strain?
Autorzy:
Mathieu ME; Department of Kinesiology, University of Montreal, Montreal, QC, Canada.; Metabolic Health and Complex Diseases, Sainte-Justine UHC Research Center, Montreal, QC, Canada.
Tremblay A; Department of Kinesiology, Faculty of Medicine, Laval University, Quebec City, QC, Canada.
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Źródło:
International journal of obesity (2005) [Int J Obes (Lond)] 2015 Nov; Vol. 39 (11), pp. 1666. Date of Electronic Publication: 2015 Aug 07.
Typ publikacji:
Letter; Comment
MeSH Terms:
Obesity*
Stress, Psychological*
Humans ; Occupational Diseases ; Risk Factors
Opinia redakcyjna
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Examination of whether early weight loss predicts 1-year weight loss among those enrolled in an Internet-based weight loss program.
Autorzy:
Unick JL; Weight Control and Diabetes Research Center, The Miriam Hospital and Brown Medical School, Providence, RI, USA.
Leahey T; Weight Control and Diabetes Research Center, The Miriam Hospital and Brown Medical School, Providence, RI, USA.
Kent K; Weight Control and Diabetes Research Center, The Miriam Hospital and Brown Medical School, Providence, RI, USA.
Wing RR; Weight Control and Diabetes Research Center, The Miriam Hospital and Brown Medical School, Providence, RI, USA.
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Źródło:
International journal of obesity (2005) [Int J Obes (Lond)] 2015 Oct; Vol. 39 (10), pp. 1558-60. Date of Electronic Publication: 2015 May 18.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Exercise*
Internet*
Weight Reduction Programs*
Behavior Therapy/*methods
Diet, Reducing/*methods
Obesity/*prevention & control
Adult ; Body Mass Index ; Female ; Follow-Up Studies ; Humans ; Male ; Treatment Outcome ; Weight Loss
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Associations of maternal weight status prior and during pregnancy with neonatal cardiometabolic markers at birth: the Healthy Start study.
Autorzy:
Lemas DJ; Department of Pediatrics, Section of Neonatology, University of Colorado Denver, Aurora, CO, USA.
Brinton JT; Department of Medicine, University of Colorado Denver, Denver, CO, USA.
Shapiro AL; Department of Epidemiology, Colorado School of Public Health, University of Colorado Denver, Aurora, CO, USA.
Glueck DH; Department of Biostatistics and Informatics, Colorado School of Public Health, Aurora, CO, USA.
Friedman JE; Department of Pediatrics, Section of Neonatology, University of Colorado Denver, Aurora, CO, USA.
Dabelea D; Department of Epidemiology, Colorado School of Public Health, University of Colorado Denver, Aurora, CO, USA.
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Źródło:
International journal of obesity (2005) [Int J Obes (Lond)] 2015 Oct; Vol. 39 (10), pp. 1437-42. Date of Electronic Publication: 2015 Jun 09.
Typ publikacji:
Journal Article; Observational Study; Research Support, N.I.H., Extramural
MeSH Terms:
Weight Gain*
Cardiovascular Diseases/*etiology
Obesity/*complications
Plethysmography/*methods
Adiposity ; Adult ; Birth Weight ; Blood Glucose/metabolism ; Body Mass Index ; Cardiovascular Diseases/blood ; Cardiovascular Diseases/epidemiology ; Cardiovascular Diseases/prevention & control ; Colorado/epidemiology ; Female ; Fetal Development ; Humans ; Infant, Newborn ; Insulin/blood ; Leptin/blood ; Lipoproteins, HDL/blood ; Longitudinal Studies ; Obesity/blood ; Obesity/epidemiology ; Obesity/prevention & control ; Pregnancy ; Risk Factors ; Triglycerides/blood
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
A percutaneous needle biopsy technique for sampling the supraclavicular brown adipose tissue depot of humans.
Autorzy:
Chondronikola M; Metabolism Unit, Shriners Hospitals for Children-Galveston, Galveston, TX, USA.; Department of Preventive Medicine and Community Health, University of Texas Medical Branch, Galveston, TX, USA.; Department of Nutrition and Metabolism, Division of Rehabilitation Sciences, University of Texas Medical Branch, Galveston, TX, USA.; Department of Nutrition and Dietetics, Harokopio University of Athens, Athens, Greece.
Annamalai P; Department of Interventional Radiology, University of Texas Medical Branch, Galveston, TX, USA.
Chao T; Department of Preventive Medicine and Community Health, University of Texas Medical Branch, Galveston, TX, USA.; Department of Nutrition and Metabolism, Division of Rehabilitation Sciences, University of Texas Medical Branch, Galveston, TX, USA.
Porter C; Metabolism Unit, Shriners Hospitals for Children-Galveston, Galveston, TX, USA.; Department of Surgery, University of Texas Medical Branch, Galveston, TX, USA.
Saraf MK; Metabolism Unit, Shriners Hospitals for Children-Galveston, Galveston, TX, USA.; Department of Surgery, University of Texas Medical Branch, Galveston, TX, USA.
Cesani F; Department of Nuclear Medicine, University of Texas Medical Branch, Galveston, TX, USA.
Sidossis LS; Metabolism Unit, Shriners Hospitals for Children-Galveston, Galveston, TX, USA.; Department of Nutrition and Metabolism, Division of Rehabilitation Sciences, University of Texas Medical Branch, Galveston, TX, USA.; Department of Nutrition and Dietetics, Harokopio University of Athens, Athens, Greece.; Department of Surgery, University of Texas Medical Branch, Galveston, TX, USA.; Institute for Translational Sciences, University of Texas Medical Branch, Galveston, TX, USA.; Sealy Center on Aging, University of Texas Medical Branch, Galveston, TX, USA.; Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX, USA.
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Źródło:
International journal of obesity (2005) [Int J Obes (Lond)] 2015 Oct; Vol. 39 (10), pp. 1561-4. Date of Electronic Publication: 2015 Apr 29.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Positron-Emission Tomography*
Tomography, X-Ray Computed*
Adipose Tissue, Brown/*pathology
Biopsy, Fine-Needle/*methods
Obesity/*pathology
Adult ; Cold Temperature ; Humans ; Male ; Obesity/metabolism ; Thermogenesis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Maternal obesity: significance on the preterm neonate.
Autorzy:
Khalak R; Division of Neonatology, Department of Pediatrics, Albany Medical Center, Albany, NY, USA.
Cummings J; Division of Neonatology, Department of Pediatrics, Albany Medical Center, Albany, NY, USA.
Dexter S; Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Albany Medical Center, Albany, NY, USA.
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Źródło:
International journal of obesity (2005) [Int J Obes (Lond)] 2015 Oct; Vol. 39 (10), pp. 1433-6. Date of Electronic Publication: 2015 Jun 08.
Typ publikacji:
Journal Article; Multicenter Study
MeSH Terms:
Pregnant Women*
Cesarean Section/*statistics & numerical data
Fetal Macrosomia/*epidemiology
Intensive Care, Neonatal/*statistics & numerical data
Obesity/*complications
Pregnancy Complications/*epidemiology
Premature Birth/*epidemiology
Adult ; Body Mass Index ; Databases, Factual ; Female ; Fetal Macrosomia/etiology ; Humans ; Infant, Newborn ; Infant, Premature ; Infant, Small for Gestational Age ; Intensive Care, Neonatal/methods ; New York/epidemiology ; Obesity/epidemiology ; Obesity/prevention & control ; Pregnancy ; Pregnancy Complications/etiology ; Pregnancy Outcome ; Premature Birth/etiology ; Retrospective Studies
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Lack of mature lymphocytes results in obese but metabolically healthy mice when fed a high-fat diet.
Autorzy:
Liu X; Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Huh JY; Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Gong H; Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Chamberland JP; Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.; Section of Endocrinology, Boston VA Healthcare System, Harvard Medical School, Boston, MA, USA.
Brinkoetter MT; Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Hamnvik OP; Section of Endocrinology, Boston VA Healthcare System, Harvard Medical School, Boston, MA, USA.
Mantzoros CS; Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.; Section of Endocrinology, Boston VA Healthcare System, Harvard Medical School, Boston, MA, USA.
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Źródło:
International journal of obesity (2005) [Int J Obes (Lond)] 2015 Oct; Vol. 39 (10), pp. 1548-57. Date of Electronic Publication: 2015 May 21.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Homeodomain Proteins/*metabolism
Hypothalamus/*pathology
Insulin/*metabolism
Lymphocytes/*metabolism
Obesity/*pathology
Adaptive Immunity ; Animals ; Diet, High-Fat ; Disease Models, Animal ; Inflammation ; Insulin Resistance ; Male ; Mice ; Mice, Inbred C57BL ; Obesity/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Wyświetlanie 1-20 z 1703

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