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Tytuł :
HOW TO TREAT PATIENTS AFTER SERIOUS ADVERSE EFFECTS CAUSED BY TNF INHIBITORS?
Autorzy :
Sršen S; 1Department of Pediatrics, Split University Hospital Centre, University of Split School of Medicine, Split, Croatia; 2Department of Pediatrics, Division of Pediatric Rheumatology and Immunology, Zagreb University Hospital Centre, University of Zagreb School of Medicine, Zagreb, Croatia.
Marušić E; 1Department of Pediatrics, Split University Hospital Centre, University of Split School of Medicine, Split, Croatia; 2Department of Pediatrics, Division of Pediatric Rheumatology and Immunology, Zagreb University Hospital Centre, University of Zagreb School of Medicine, Zagreb, Croatia.
Metličić V; 1Department of Pediatrics, Split University Hospital Centre, University of Split School of Medicine, Split, Croatia; 2Department of Pediatrics, Division of Pediatric Rheumatology and Immunology, Zagreb University Hospital Centre, University of Zagreb School of Medicine, Zagreb, Croatia.
Stričević L; 1Department of Pediatrics, Split University Hospital Centre, University of Split School of Medicine, Split, Croatia; 2Department of Pediatrics, Division of Pediatric Rheumatology and Immunology, Zagreb University Hospital Centre, University of Zagreb School of Medicine, Zagreb, Croatia.
Frković M; 1Department of Pediatrics, Split University Hospital Centre, University of Split School of Medicine, Split, Croatia; 2Department of Pediatrics, Division of Pediatric Rheumatology and Immunology, Zagreb University Hospital Centre, University of Zagreb School of Medicine, Zagreb, Croatia.
Jelušić M; 1Department of Pediatrics, Split University Hospital Centre, University of Split School of Medicine, Split, Croatia; 2Department of Pediatrics, Division of Pediatric Rheumatology and Immunology, Zagreb University Hospital Centre, University of Zagreb School of Medicine, Zagreb, Croatia.
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Źródło :
Acta clinica Croatica [Acta Clin Croat] 2020 Mar; Vol. 59 (1), pp. 161-165.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Peripheral Nervous System Diseases*
Tumor Necrosis Factor Inhibitors*/adverse effects
Adalimumab/adverse effects ; Child ; Child, Preschool ; Female ; Humans ; Male ; Retrospective Studies ; Tumor Necrosis Factor-alpha
Czasopismo naukowe
Tytuł :
Successful treatment of tumor necrosis factor inhibitor-resistant cutaneous polyarteritis nodosa with tocilizumab.
Autorzy :
Inoue N; Department of Pediatrics, School of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan.
Shimizu M; Department of Pediatrics, School of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan.
Mizuta M; Department of Pediatrics, School of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan.
Yachie A; Department of Pediatrics, School of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan.
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Źródło :
Pediatrics international : official journal of the Japan Pediatric Society [Pediatr Int] 2020 Jun; Vol. 62 (6), pp. 753-755. Date of Electronic Publication: 2020 Jun 08.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Antibodies, Monoclonal, Humanized/*administration & dosage
Polyarteritis Nodosa/*drug therapy
Tumor Necrosis Factor-alpha/*metabolism
Child ; Drug Resistance ; Female ; Humans ; Interleukin-6/blood ; Polyarteritis Nodosa/diagnosis ; Positron-Emission Tomography ; Skin/pathology ; Treatment Outcome ; Tumor Necrosis Factor Inhibitors/adverse effects ; Tumor Necrosis Factor Inhibitors/therapeutic use
Czasopismo naukowe
Tytuł :
Emodin induced necroptosis in the glioma cell line U251 via the TNF-α/RIP1/RIP3 pathway.
Autorzy :
Zhou J; Graduate School, Tianjin Medical University, Tianjin, 300070, People's Republic of China.; Department of Neurosurgery, Affiliated Hospital of Jining Medical University, & Shandong Provincial Key Laboratory of Stem Cells and Neuro-oncology, Jining, Shandong, 272029, People's Republic of China.
Li G; Department of Neurosurgery, Affiliated Hospital of Jining Medical University, & Shandong Provincial Key Laboratory of Stem Cells and Neuro-oncology, Jining, Shandong, 272029, People's Republic of China.
Han G; Department of Neurosurgery, Affiliated Hospital of Jining Medical University, & Shandong Provincial Key Laboratory of Stem Cells and Neuro-oncology, Jining, Shandong, 272029, People's Republic of China.
Feng S; Department of Neurosurgery, Affiliated Hospital of Jining Medical University, & Shandong Provincial Key Laboratory of Stem Cells and Neuro-oncology, Jining, Shandong, 272029, People's Republic of China.
Liu Y; Department of Traditional Chinese Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, People's Republic of China.
Chen J; Department of Neurosurgery, Affiliated Hospital of Jining Medical University, & Shandong Provincial Key Laboratory of Stem Cells and Neuro-oncology, Jining, Shandong, 272029, People's Republic of China.; Clinical Medical College, Jining Medical University, Jining, Shandong, 272029, People's Republic of China.
Liu C; Department of Neurosurgery, Affiliated Hospital of Jining Medical University, & Shandong Provincial Key Laboratory of Stem Cells and Neuro-oncology, Jining, Shandong, 272029, People's Republic of China.; Clinical Medical College, Jining Medical University, Jining, Shandong, 272029, People's Republic of China.
Zhao L; Department of Infectious Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Jin F; Department of Neurosurgery, Affiliated Hospital of Jining Medical University, & Shandong Provincial Key Laboratory of Stem Cells and Neuro-oncology, Jining, Shandong, 272029, People's Republic of China. .
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Źródło :
Investigational new drugs [Invest New Drugs] 2020 Feb; Vol. 38 (1), pp. 50-59. Date of Electronic Publication: 2019 Mar 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Necroptosis*
Necrosis*
Emodin/*pharmacology
Glioma/*pathology
Nuclear Pore Complex Proteins/*metabolism
RNA-Binding Proteins/*metabolism
Receptor-Interacting Protein Serine-Threonine Kinases/*metabolism
Tumor Necrosis Factor-alpha/*metabolism
Animals ; Cell Cycle ; Cell Proliferation ; Female ; Glioma/drug therapy ; Glioma/metabolism ; Humans ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Nuclear Pore Complex Proteins/genetics ; Protein Kinase Inhibitors/pharmacology ; RNA-Binding Proteins/genetics ; Reactive Oxygen Species/metabolism ; Receptor-Interacting Protein Serine-Threonine Kinases/genetics ; Signal Transduction ; Tumor Cells, Cultured ; Tumor Necrosis Factor-alpha/genetics ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
Effects of myeloid cell-restricted TNF inhibitors in vitro and in vivo.
Autorzy :
Drutskaya MS; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.
Nosenko MA; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.
Gorshkova EA; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.; Lomonosov Moscow State University, Moscow, Russia.
Mokhonov VV; Blokhina Scientific Research Institute of Epidemiology and Microbiology of Nizhny Novgorod, Nizhny Novgorod, Russia.
Zvartsev RV; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.
Polinova AI; Lomonosov Moscow State University, Moscow, Russia.
Kruglov AA; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.; Lomonosov Moscow State University, Moscow, Russia.; German Rheumatism Research Center (DRFZ), a Leibniz Institute, Berlin, Germany.
Nedospasov SA; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.; Lomonosov Moscow State University, Moscow, Russia.; Institute of Cell Biology and Neurobiology, Charité-Universitätsmedizin Berlin, Berlin, Germany.
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Źródło :
Journal of leukocyte biology [J Leukoc Biol] 2020 Jun; Vol. 107 (6), pp. 933-939. Date of Electronic Publication: 2020 Feb 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antibodies, Monoclonal/*pharmacology
Arthritis, Experimental/*therapy
CD11b Antigen/*antagonists & inhibitors
Calcium-Binding Proteins/*antagonists & inhibitors
Immunoglobulin Heavy Chains/*pharmacology
Myeloid Progenitor Cells/*drug effects
Receptors, G-Protein-Coupled/*antagonists & inhibitors
Tumor Necrosis Factor Inhibitors/*pharmacology
Animals ; Antirheumatic Agents/pharmacology ; Arthritis, Experimental/genetics ; Arthritis, Experimental/immunology ; Arthritis, Experimental/pathology ; CD11b Antigen/genetics ; CD11b Antigen/immunology ; Calcium-Binding Proteins/genetics ; Calcium-Binding Proteins/immunology ; Gene Expression ; Humans ; Infliximab/pharmacology ; Lipopolysaccharides/pharmacology ; Macrophages/drug effects ; Macrophages/immunology ; Mice ; Mice, Transgenic ; Myeloid Progenitor Cells/immunology ; Receptors, G-Protein-Coupled/genetics ; Receptors, G-Protein-Coupled/immunology ; Tumor Necrosis Factor-alpha/genetics ; Tumor Necrosis Factor-alpha/immunology
Czasopismo naukowe
Tytuł :
[Cost of illness in axial spondylarthritis for patients with and without tumor necrosis factor inhibitor treatment: results of a routine data analysis].
Autorzy :
Redeker I; Medizinische Klinik für Gastroenterologie, Infektiologie und Rheumatologie, Charité - Universitätsmedizin Berlin, Hindenburgdamm 30, 12203, Berlin, Deutschland. .; Programmbereich Epidemiologie, Deutsches Rheuma-Forschungszentrum, Charitéplatz 1, 10117, Berlin, Deutschland. .
Callhoff J; Programmbereich Epidemiologie, Deutsches Rheuma-Forschungszentrum, Charitéplatz 1, 10117, Berlin, Deutschland.
Hoffmann F; Department für Versorgungsforschung, Carl von Ossietzky Universität, Ammerländer Heerstr. 140, 26129, Oldenburg, Deutschland.
Saam J; BARMER Institut für Gesundheitssystemforschung, BARMER Gesetzliche Krankenversicherung, Lichtscheider Str. 89, 42285, Wuppertal, Deutschland.
Haibel H; Medizinische Klinik für Gastroenterologie, Infektiologie und Rheumatologie, Charité - Universitätsmedizin Berlin, Hindenburgdamm 30, 12203, Berlin, Deutschland.
Sieper J; Medizinische Klinik für Gastroenterologie, Infektiologie und Rheumatologie, Charité - Universitätsmedizin Berlin, Hindenburgdamm 30, 12203, Berlin, Deutschland.
Zink A; Programmbereich Epidemiologie, Deutsches Rheuma-Forschungszentrum, Charitéplatz 1, 10117, Berlin, Deutschland.; Medizinische Klinik mit Schwerpunkt Rheumatologie und Klinische Immunologie, Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Deutschland.
Poddubnyy D; Medizinische Klinik für Gastroenterologie, Infektiologie und Rheumatologie, Charité - Universitätsmedizin Berlin, Hindenburgdamm 30, 12203, Berlin, Deutschland.; Programmbereich Epidemiologie, Deutsches Rheuma-Forschungszentrum, Charitéplatz 1, 10117, Berlin, Deutschland.
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Transliterated Title :
Krankheitskosten bei axialer Spondyloarthritis für Patienten mit und ohne Tumor-Nekrose-Faktor-Inhibitor-Behandlung: Ergebnisse einer Routinedatenanalyse.
Źródło :
Zeitschrift fur Rheumatologie [Z Rheumatol] 2020 Feb; Vol. 79 (1), pp. 85-94.
Typ publikacji :
Journal Article
MeSH Terms :
Antirheumatic Agents*/therapeutic use
Health Care Costs*/statistics & numerical data
Spondylarthritis*/complications
Spondylarthritis*/drug therapy
Spondylarthritis*/economics
Tumor Necrosis Factor Inhibitors*/therapeutic use
Absenteeism ; Cost of Illness ; Data Analysis ; Germany ; Humans ; Treatment Outcome ; Tumor Necrosis Factor-alpha
Czasopismo naukowe
Tytuł :
Anti-TNF Therapy Is Emerging as the Primary Treatment Modality in Pediatric Inflammatory Bowel Disease.
Autorzy :
Niklinska-Schirtz BJ; Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia.
Kugathasan S; Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia.
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Źródło :
Inflammatory bowel diseases [Inflamm Bowel Dis] 2020 Jan 01; Vol. 26 (1), pp. 139-140.
Typ publikacji :
Editorial; Comment
MeSH Terms :
Inflammatory Bowel Diseases*
Tumor Necrosis Factor-alpha*
Canada ; Child ; Humans ; Infliximab ; Tumor Necrosis Factor Inhibitors
Opinia redakcyjna
Tytuł :
Can machine learning predict responses to TNF inhibitors?
Autorzy :
Nair N; Centre of Genetics & Genomics Versus Arthritis, Manchester Academic Health Sciences Centre, The University of Manchester, Manchester, UK. .
Wilson AG; University College Dublin Centre for Arthritis Research, Conway Institute, University College Dublin, Dublin, Ireland. .
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Źródło :
Nature reviews. Rheumatology [Nat Rev Rheumatol] 2019 Dec; Vol. 15 (12), pp. 702-704.
Typ publikacji :
Journal Article; Comment
MeSH Terms :
Arthritis, Rheumatoid*
Tumor Necrosis Factor Inhibitors*
Genetic Markers ; Humans ; Machine Learning ; Tumor Necrosis Factor-alpha
Czasopismo naukowe
Tytuł :
An unexpected case of disseminated tuberculosis from tumour necrosis factor inhibition.
Autorzy :
Con D; Medical Registrar, Department of General Medicine, Eastern Health, VIC, Australia.
Gador-Whyte A; Infectious Diseases Advanced Trainee, Department of Infectious Diseases, Eastern Health, VIC, Australia.
MacGinley R; Nephrologist and General Physician, Department of General Medicine, Eastern Health, VIC, Australia; Eastern Health Clinical School Monash University, Melbourne, VIC, Australia.
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Źródło :
The New Zealand medical journal [N Z Med J] 2020 Jun 26; Vol. 133 (1517), pp. 126-128. Date of Electronic Publication: 2020 Jun 26.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Infliximab/*adverse effects
Rheumatic Diseases/*drug therapy
Tuberculosis/*chemically induced
Tumor Necrosis Factor Inhibitors/*adverse effects
Adult ; Antirheumatic Agents/adverse effects ; Brain/diagnostic imaging ; Humans ; Magnetic Resonance Imaging ; Male ; Tuberculosis/diagnosis ; Tumor Necrosis Factor-alpha/antagonists & inhibitors
Czasopismo naukowe
Tytuł :
Tapering tumour necrosis factor inhibitors in rheumatoid arthritis: a retrospective study.
Autorzy :
Hacioglu A; Istanbul University-Cerrahpasa, Cerrahpasa Medical School, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey.
Hatemi G; Istanbul University-Cerrahpasa, Cerrahpasa Medical School, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey.
Esatoglu SN; Istanbul University-Cerrahpasa, Cerrahpasa Medical School, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey.
Hamuryudan V; Istanbul University-Cerrahpasa, Cerrahpasa Medical School, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey. .
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Źródło :
Clinical and experimental rheumatology [Clin Exp Rheumatol] 2019 Nov-Dec; Vol. 37 Suppl 122 (6), pp. 8. Date of Electronic Publication: 2018 Apr 19.
Typ publikacji :
Letter
MeSH Terms :
Antirheumatic Agents*/administration & dosage
Antirheumatic Agents*/therapeutic use
Arthritis, Rheumatoid*/drug therapy
Tumor Necrosis Factor Inhibitors*/administration & dosage
Tumor Necrosis Factor Inhibitors*/therapeutic use
Humans ; Remission Induction ; Retrospective Studies ; Tumor Necrosis Factor-alpha/antagonists & inhibitors
Opinia redakcyjna
Tytuł :
Reversal of anti-drug antibodies against tumor necrosis factor inhibitors with addition of immunomodulators: A systematic review and meta-analysis.
Autorzy :
Dhindsa BS; Department of Internal Medicine, University of Nevada Las Vegas School of Medicine, 1701 W Charleston Blvd Ste 230, Las Vegas, NV, 89102, USA.
Dhaliwal A; Division of Gastroenterology and Hepatology, University of Nebraska Medical Center, 982000 Nebraska Medical Center, Omaha, NE, 68198-2000, USA.
Mashiana HS; Division of Gastroenterology and Hepatology, University of Nebraska Medical Center, 982000 Nebraska Medical Center, Omaha, NE, 68198-2000, USA.
Saghir SM; Department of Internal Medicine, University of Nevada Las Vegas School of Medicine, 1701 W Charleston Blvd Ste 230, Las Vegas, NV, 89102, USA.
Sayles H; Department of Biostatistics, University of Nebraska Medical Center, 982000 Nebraska Medical Center, Omaha, NE, 68198-2000, USA.
Mubder M; Department of Internal Medicine, University of Nevada Las Vegas School of Medicine, 1701 W Charleston Blvd Ste 230, Las Vegas, NV, 89102, USA.
Ohning G; Division of Gastroenterology, University of Nevada Las Vegas School of Medicine, 1701 W Charleston Blvd Ste 230, Las Vegas, NV, 89102, USA.
Eichele D; Division of Gastroenterology and Hepatology, University of Nebraska Medical Center, 982000 Nebraska Medical Center, Omaha, NE, 68198-2000, USA. .
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Źródło :
Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology [Indian J Gastroenterol] 2020 Apr; Vol. 39 (2), pp. 153-160. Date of Electronic Publication: 2020 May 28.
Typ publikacji :
Journal Article; Meta-Analysis; Systematic Review
MeSH Terms :
Antibodies/*blood
Antibody Formation/*drug effects
Immunologic Factors/*administration & dosage
Immunologic Factors/*pharmacology
Inflammatory Bowel Diseases/*drug therapy
Inflammatory Bowel Diseases/*immunology
Mercaptopurine/*analogs & derivatives
Methotrexate/*administration & dosage
Methotrexate/*pharmacology
Tumor Necrosis Factor Inhibitors/*immunology
Tumor Necrosis Factor Inhibitors/*therapeutic use
Mercaptopurine/administration & dosage ; Mercaptopurine/pharmacology ; Treatment Outcome ; Tumor Necrosis Factor Inhibitors/adverse effects ; Tumor Necrosis Factor-alpha
Czasopismo naukowe
Tytuł :
iRhom2 and TNF: Partners or enemies?
Autorzy :
Badenes M; Instituto Gulbenkian de Ciência (IGC), Oeiras, Portugal. .
Adrain C; Instituto Gulbenkian de Ciência (IGC), Oeiras, Portugal. .; Centre for Cancer Research and Cell Biology, Queen's University, Belfast, UK.
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Źródło :
Science signaling [Sci Signal] 2019 Oct 29; Vol. 12 (605). Date of Electronic Publication: 2019 Oct 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review; Comment
MeSH Terms :
Cholestasis*
Receptors, Tumor Necrosis Factor*
ADAM17 Protein ; Humans ; Liver Cirrhosis ; Signal Transduction ; Tumor Necrosis Factor-alpha
Czasopismo naukowe
Tytuł :
Editorial: The Role of TNF-TNFR2 Signal in Immunosuppressive Cells and Its Therapeutic Implications.
Autorzy :
Chen X; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau SAR, China.
Plebanski M; School of Health and Biomedical Sciences, RMIT University, Bundoora, VIC, Australia.
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Źródło :
Frontiers in immunology [Front Immunol] 2019 Sep 06; Vol. 10, pp. 2126. Date of Electronic Publication: 2019 Sep 06 (Print Publication: 2019).
Typ publikacji :
Editorial; Research Support, Non-U.S. Gov't; Comment
MeSH Terms :
Receptors, Tumor Necrosis Factor, Type II*
T-Lymphocytes, Regulatory*
Epigenesis, Genetic ; Forkhead Transcription Factors ; Humans ; Tumor Necrosis Factor-alpha
Raport
Tytuł :
Risk of neuroinflammatory events in arthritis patients treated with tumour necrosis factor alpha inhibitors: a collaborative population-based cohort study from Denmark and Sweden.
Autorzy :
Kopp TI; The Danish Multiple Sclerosis Registry, Department of Neurology, Rigshospitalet Glostrup, Glostrup, Denmark .; Center for Clinical Research and Prevention, Frederiksberg Hospital, Frederiksberg, Denmark.
Delcoigne B; Clinical Epidemiology Division, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.
Arkema EV; Clinical Epidemiology Division, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.
Jacobsen RK; Center for Clinical Research and Prevention, Frederiksberg Hospital, Frederiksberg, Denmark.
Magyari M; The Danish Multiple Sclerosis Registry, Department of Neurology, Rigshospitalet Glostrup, Glostrup, Denmark.; Danish Multiple Sclerosis Center, Department of Neurology, Rigshospitalet, Kobenhavn, Denmark.
Ibfelt EH; Center for Clinical Research and Prevention, Frederiksberg Hospital, Frederiksberg, Denmark.; Clinical Epidemiology, Steno Diabetes Center Copenhagen, Gentofte, Denmark.
Locht H; Department of Rheumatology, Frederiksberg Hospital, Frederiksberg, Denmark.
Sellebjerg F; Danish Multiple Sclerosis Center, Department of Neurology, Rigshospitalet, Kobenhavn, Denmark.
Cordtz RL; Center for Rheumatology and Spine Diseases - Gentofte, Rigshospitalet, Hellerup, Denmark.
Jensen DV; Center for Rheumatology and Spine Diseases - Gentofte, Rigshospitalet, Hellerup, Denmark.
Askling J; Clinical Epidemiology Division, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.; Rheumatology, Karolinska University Hospital, Stockholm, Sweden.
Dreyer L; Department of Rheumatology, Aalborg University Hospital, Aalborg, Denmark.; Department of Clinical Medicine, Aalborg University, Aalborg, Denmark.
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Źródło :
Annals of the rheumatic diseases [Ann Rheum Dis] 2020 May; Vol. 79 (5), pp. 566-572. Date of Electronic Publication: 2020 Mar 11.
Typ publikacji :
Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
MeSH Terms :
Registries*
Arthritis, Psoriatic/*drug therapy
Arthritis, Rheumatoid/*drug therapy
Demyelinating Diseases/*chemically induced
Spondylitis, Ankylosing/*drug therapy
Tumor Necrosis Factor Inhibitors/*adverse effects
Aged ; Arthritis, Psoriatic/diagnosis ; Arthritis, Rheumatoid/diagnosis ; Cohort Studies ; Demyelinating Diseases/epidemiology ; Denmark ; Female ; Humans ; Incidence ; Male ; Middle Aged ; Nervous System Diseases/chemically induced ; Nervous System Diseases/epidemiology ; Prognosis ; Proportional Hazards Models ; Retrospective Studies ; Risk Assessment ; Spondylitis, Ankylosing/diagnosis ; Sweden ; Tumor Necrosis Factor Inhibitors/administration & dosage ; Tumor Necrosis Factor-alpha/adverse effects ; Tumor Necrosis Factor-alpha/antagonists & inhibitors
Czasopismo naukowe
Tytuł :
Personalized medicine in rheumatoid arthritis: How immunogenicity impacts use of TNF inhibitors.
Autorzy :
Bodio C; Istituto Auxologico Italiano, IRCCS, Experimental Laboratory of Immuno-rheumatology, Milan, Italy.
Grossi C; Istituto Auxologico Italiano, IRCCS, Experimental Laboratory of Immuno-rheumatology, Milan, Italy.
Pregnolato F; Istituto Auxologico Italiano, IRCCS, Experimental Laboratory of Immuno-rheumatology, Milan, Italy.
Favalli EG; Rheumatology Department, ASST Gaetano Pini-CTO, Milan, Italy.
Biggioggero M; Rheumatology Department, ASST Gaetano Pini-CTO, Milan, Italy.
Marchesoni A; Rheumatology Department, ASST Gaetano Pini-CTO, Milan, Italy.
Murgo A; Rheumatology Department, ASST Gaetano Pini-CTO, Milan, Italy.
Filippini M; Rheumatology and Clinical Immunology, ASST Spedali Civili di Brescia, Italy.
Migliorini P; Clinical Immunology, University of Pisa, Italy.
Caporali R; Department of Clinical Sciences and Community Health, University of Milan, Italy; IRCCS Policlinico S. Matteo Foundation, Pavia, Italy.
Pellerito R; Rehumatology, Ospedale Mauriziano, Torino, Italy.
Ciccia F; Rheumatology, University of Campania, Napoli, Italy.
Sarzi-Puttini P; Rheumatology Unit, ASST Fatebenefratelli-Sacco, University of Milan, Italy.
Perosa F; Department of Biomedical Science and Human Oncology, Rheumatologic and Systemic Autoimmune Diseases Unit, University of Bari Medical School, Bari, Italy.
Paolazzi G; UOC Reumatologia, Ospedale Santa Chiara, Trento, Italy.
Hollan I; Lillehammer Hospital for Rheumatic Diseases, Lillehammer, Norway and Brigham and Women's Hospital, Cardiology Division, Boston, USA.
Bendtzen K; Institute for Inflammation Research IIR 7521, Rigshospitalet Natl. Univ. Hospital Copenhagen, Denmark.
Meroni PL; Istituto Auxologico Italiano, IRCCS, Experimental Laboratory of Immuno-rheumatology, Milan, Italy. Electronic address: .
Borghi MO; Istituto Auxologico Italiano, IRCCS, Experimental Laboratory of Immuno-rheumatology, Milan, Italy; Department of Clinical Sciences and Community Health, University of Milan, Italy.
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Źródło :
Autoimmunity reviews [Autoimmun Rev] 2020 May; Vol. 19 (5), pp. 102509. Date of Electronic Publication: 2020 Mar 12.
Typ publikacji :
Journal Article; Multicenter Study
MeSH Terms :
Precision Medicine*
Antirheumatic Agents/*therapeutic use
Arthritis, Rheumatoid/*drug therapy
Arthritis, Rheumatoid/*immunology
Tumor Necrosis Factor Inhibitors/*therapeutic use
Adalimumab/therapeutic use ; Biosimilar Pharmaceuticals/therapeutic use ; Cross-Sectional Studies ; Etanercept/therapeutic use ; Female ; Humans ; Infliximab/therapeutic use ; Male ; Middle Aged ; Prospective Studies ; Treatment Outcome ; Tumor Necrosis Factor-alpha/antagonists & inhibitors
Czasopismo naukowe
Tytuł :
Two distinct ubiquitin-binding motifs in A20 mediate its anti-inflammatory and cell-protective activities.
Autorzy :
Martens A; VIB Center for Inflammation Research, Ghent, Belgium.; Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium.
Priem D; VIB Center for Inflammation Research, Ghent, Belgium.; Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium.
Hoste E; VIB Center for Inflammation Research, Ghent, Belgium.; Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium.
Vetters J; VIB Center for Inflammation Research, Ghent, Belgium.; Department of Internal Medicine and Pediatrics, Ghent University, Ghent, Belgium.
Rennen S; VIB Center for Inflammation Research, Ghent, Belgium.; Department of Internal Medicine and Pediatrics, Ghent University, Ghent, Belgium.
Catrysse L; VIB Center for Inflammation Research, Ghent, Belgium.; Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium.
Voet S; VIB Center for Inflammation Research, Ghent, Belgium.; Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium.
Deelen L; VIB Center for Inflammation Research, Ghent, Belgium.; Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium.
Sze M; VIB Center for Inflammation Research, Ghent, Belgium.; Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium.
Vikkula H; VIB Center for Inflammation Research, Ghent, Belgium.; Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium.
Slowicka K; VIB Center for Inflammation Research, Ghent, Belgium.; Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium.
Hochepied T; VIB Center for Inflammation Research, Ghent, Belgium.; Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium.
Iliaki K; Biomedical Sciences Research Center 'Alexander Fleming', Vari, Greece.
Wullaert A; VIB Center for Inflammation Research, Ghent, Belgium.; Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium.; Department of Internal Medicine and Pediatrics, Ghent University, Ghent, Belgium.
Janssens S; VIB Center for Inflammation Research, Ghent, Belgium.; Department of Internal Medicine and Pediatrics, Ghent University, Ghent, Belgium.
Lamkanfi M; VIB Center for Inflammation Research, Ghent, Belgium.; Department of Internal Medicine and Pediatrics, Ghent University, Ghent, Belgium.; Janssen Immunosciences, World without Disease Accelerator, Pharmaceutical Companies of Johnson & Johnson, Beerse, Belgium.
Beyaert R; VIB Center for Inflammation Research, Ghent, Belgium.; Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium.
Armaka M; Biomedical Sciences Research Center 'Alexander Fleming', Vari, Greece.
Bertrand MJM; VIB Center for Inflammation Research, Ghent, Belgium.; Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium.
van Loo G; VIB Center for Inflammation Research, Ghent, Belgium. .; Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium. .
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Źródło :
Nature immunology [Nat Immunol] 2020 Apr; Vol. 21 (4), pp. 381-387. Date of Electronic Publication: 2020 Mar 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Inflammation/*metabolism
Tumor Necrosis Factor alpha-Induced Protein 3/*metabolism
Animals ; Epithelial Cells/metabolism ; Humans ; Mice ; Mice, Inbred C57BL ; Myeloid Cells/metabolism ; Polyubiquitin/metabolism ; Protein Binding/physiology ; Signal Transduction/physiology ; Tumor Necrosis Factor-alpha/metabolism ; Ubiquitin/metabolism ; Ubiquitination/physiology ; Zinc Fingers/physiology
Czasopismo naukowe
Tytuł :
CD70-mediated CD27 expression downregulation contributed to the regulatory B10 cell impairment in rheumatoid arthritis.
Autorzy :
Shi L; Department of Rheumatology and Immunology, Peking University International Hospital, Beijing, China; Department of Rheumatology and Immunology, Peking University People's Hospital & Beijing Key Laboratory for Rheumatism Mechanism and Immune Diagnosis (BZ0135), Beijing, China; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, China.
Hu F; Department of Rheumatology and Immunology, Peking University People's Hospital & Beijing Key Laboratory for Rheumatism Mechanism and Immune Diagnosis (BZ0135), Beijing, China.
Zhu L; Department of Rheumatology and Immunology, Peking University People's Hospital & Beijing Key Laboratory for Rheumatism Mechanism and Immune Diagnosis (BZ0135), Beijing, China.
Xu C; Department of Rheumatology, Allergy and Immunology, Tan Tock Seng Hospital, Singapore.
Zhu H; Department of Rheumatology and Immunology, Peking University People's Hospital & Beijing Key Laboratory for Rheumatism Mechanism and Immune Diagnosis (BZ0135), Beijing, China.
Li Y; Department of Rheumatology and Immunology, Peking University People's Hospital & Beijing Key Laboratory for Rheumatism Mechanism and Immune Diagnosis (BZ0135), Beijing, China.
Liu H; The First People's Hospital of Yichang, China Three Gorges University, Yichang, Hubei, China.
Li C; Department of Rheumatology and Immunology, Peking University People's Hospital & Beijing Key Laboratory for Rheumatism Mechanism and Immune Diagnosis (BZ0135), Beijing, China.
Liu N; Department of Rheumatology and Immunology, Peking University People's Hospital & Beijing Key Laboratory for Rheumatism Mechanism and Immune Diagnosis (BZ0135), Beijing, China.
Xu L; Department of Rheumatology and Immunology, Peking University People's Hospital & Beijing Key Laboratory for Rheumatism Mechanism and Immune Diagnosis (BZ0135), Beijing, China.
Mu R; Department of Rheumatology and Immunology, Peking University People's Hospital & Beijing Key Laboratory for Rheumatism Mechanism and Immune Diagnosis (BZ0135), Beijing, China. Electronic address: .
Li Z; Department of Rheumatology and Immunology, Peking University People's Hospital & Beijing Key Laboratory for Rheumatism Mechanism and Immune Diagnosis (BZ0135), Beijing, China. Electronic address: .
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Źródło :
Molecular immunology [Mol Immunol] 2020 Mar; Vol. 119, pp. 92-100. Date of Electronic Publication: 2020 Jan 30.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Arthritis, Rheumatoid/*immunology
B-Lymphocytes, Regulatory/*immunology
CD27 Ligand/*metabolism
Tumor Necrosis Factor Receptor Superfamily, Member 7/*biosynthesis
Adult ; Antigens, CD19 ; B-Lymphocytes, Regulatory/metabolism ; CD24 Antigen ; Down-Regulation ; Female ; Humans ; Interleukin-10/biosynthesis ; Interleukin-1beta/metabolism ; Male ; Middle Aged ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Tytuł :
"Sclerotic Band" type of classification system and measurement of necrotic area for osteonecrosis of the femoral head.
Autorzy :
Zhang Y
Liu YW
Sun RB
Fan YN
Shi QY
Zhang LL
Li PF
Li WY
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Źródło :
Medicine [Medicine (Baltimore)] 2020 Sep 04; Vol. 99 (36), pp. e22106.
Typ publikacji :
Journal Article; Observational Study
MeSH Terms :
Femur Head Necrosis/*classification
Femur Head Necrosis/*pathology
Adult ; Cancellous Bone/pathology ; Female ; Femur Head/pathology ; Femur Head Necrosis/diagnostic imaging ; Femur Head Necrosis/surgery ; Humans ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Tomography, X-Ray Computed
Czasopismo naukowe
Tytuł :
Non-TNF inhibitor switchers versus TNF inhibitor cyclers from multicentre rheumatoid arthritis ultrasonography prospective cohort in Japan.
Autorzy :
Endo Y; Department of Immunology and Rheumatology, Division of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Medical Sciences, Nagasaki, Japan.; Kyushu multicenter rheumatoid arthritis ultrasound prospective observational cohort study group, Japan.
Kawashiri SY; Department of Immunology and Rheumatology, Division of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Medical Sciences, Nagasaki, Japan.; Kyushu multicenter rheumatoid arthritis ultrasound prospective observational cohort study group, Japan.
Morimoto S; Innovation Platform & Office for Precision Medicine, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan.
Nishino A; Department of Immunology and Rheumatology, Division of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Medical Sciences, Nagasaki, Japan.; Kyushu multicenter rheumatoid arthritis ultrasound prospective observational cohort study group, Japan.
Okamoto M; Department of Immunology and Rheumatology, Division of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Medical Sciences, Nagasaki, Japan.; Kyushu multicenter rheumatoid arthritis ultrasound prospective observational cohort study group, Japan.
Tsuji S; Department of Immunology and Rheumatology, Division of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Medical Sciences, Nagasaki, Japan.
Takatani A; Department of Immunology and Rheumatology, Division of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Medical Sciences, Nagasaki, Japan.
Shimizu T; Department of Immunology and Rheumatology, Division of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Medical Sciences, Nagasaki, Japan.
Sumiyoshi R; Department of Immunology and Rheumatology, Division of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Medical Sciences, Nagasaki, Japan.
Igawa T; Department of Immunology and Rheumatology, Division of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Medical Sciences, Nagasaki, Japan.
Koga T; Department of Immunology and Rheumatology, Division of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Medical Sciences, Nagasaki, Japan.
Iwamoto N; Department of Immunology and Rheumatology, Division of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Medical Sciences, Nagasaki, Japan.
Ichinose K; Department of Immunology and Rheumatology, Division of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Medical Sciences, Nagasaki, Japan.
Tamai M; Department of Immunology and Rheumatology, Division of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Medical Sciences, Nagasaki, Japan.
Nakamura H; Department of Immunology and Rheumatology, Division of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Medical Sciences, Nagasaki, Japan.
Origuchi T; Department of Immunology and Rheumatology, Division of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Medical Sciences, Nagasaki, Japan.
Ueki Y; Kyushu multicenter rheumatoid arthritis ultrasound prospective observational cohort study group, Japan.
Yoshitama T; Kyushu multicenter rheumatoid arthritis ultrasound prospective observational cohort study group, Japan.
Eiraku N; Kyushu multicenter rheumatoid arthritis ultrasound prospective observational cohort study group, Japan.
Matsuoka N; Kyushu multicenter rheumatoid arthritis ultrasound prospective observational cohort study group, Japan.
Okada A; Kyushu multicenter rheumatoid arthritis ultrasound prospective observational cohort study group, Japan.
Fujikawa K; Kyushu multicenter rheumatoid arthritis ultrasound prospective observational cohort study group, Japan.
Hamada H; Kyushu multicenter rheumatoid arthritis ultrasound prospective observational cohort study group, Japan.
Tsuru T; Kyushu multicenter rheumatoid arthritis ultrasound prospective observational cohort study group, Japan.
Nagano S; Kyushu multicenter rheumatoid arthritis ultrasound prospective observational cohort study group, Japan.
Arinobu Y; Kyushu multicenter rheumatoid arthritis ultrasound prospective observational cohort study group, Japan.
Hidaka T; Kyushu multicenter rheumatoid arthritis ultrasound prospective observational cohort study group, Japan.
Tada Y; Kyushu multicenter rheumatoid arthritis ultrasound prospective observational cohort study group, Japan.
Kawakami A; Department of Immunology and Rheumatology, Division of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Medical Sciences, Nagasaki, Japan.; Kyushu multicenter rheumatoid arthritis ultrasound prospective observational cohort study group, Japan.
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Źródło :
Immunological medicine [Immunol Med] 2020 Sep; Vol. 43 (3), pp. 115-120. Date of Electronic Publication: 2020 May 12.
Typ publikacji :
Comparative Study; Journal Article; Multicenter Study
MeSH Terms :
Drug Substitution*
Ultrasonography*
Abatacept/*administration & dosage
Antibodies, Monoclonal, Humanized/*administration & dosage
Antirheumatic Agents/*administration & dosage
Arthritis, Rheumatoid/*diagnostic imaging
Arthritis, Rheumatoid/*drug therapy
Tumor Necrosis Factor Inhibitors/*administration & dosage
Abatacept/adverse effects ; Aged ; Antibodies, Monoclonal, Humanized/adverse effects ; Cohort Studies ; Female ; Humans ; Japan ; Male ; Middle Aged ; Prospective Studies ; Treatment Outcome ; Tumor Necrosis Factor Inhibitors/adverse effects
Czasopismo naukowe
Tytuł :
Phytochemicals against TNFα-Mediated Neuroinflammatory Diseases.
Autorzy :
Subedi L; College of Pharmacy, Gachon University, #191, Hambakmoero, Yeonsu-gu, Incheon 21936, Korea.
Lee SE; College of Pharmacy, Gachon University, #191, Hambakmoero, Yeonsu-gu, Incheon 21936, Korea.
Madiha S; Neurochemistry and Biochemical Neuropharmacology Research Unit, Department of Biochemistry, University of Karachi, Karachi-75270, Pakistan.
Gaire BP; College of Pharmacy, Gachon University, #191, Hambakmoero, Yeonsu-gu, Incheon 21936, Korea.
Jin M; College of Medicine and Department of Health Science and Technology, GAIHST, Gachon University #155, Gaebeol-ro, Yeonsu-gu, Incheon 21999, Korea.
Yumnam S; College of Pharmacy, Gachon University, #191, Hambakmoero, Yeonsu-gu, Incheon 21936, Korea.
Kim SY; College of Pharmacy, Gachon University, #191, Hambakmoero, Yeonsu-gu, Incheon 21936, Korea.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Jan 24; Vol. 21 (3). Date of Electronic Publication: 2020 Jan 24.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Tumor Necrosis Factor-alpha*/antagonists & inhibitors
Tumor Necrosis Factor-alpha*/metabolism
Neurodegenerative Diseases/*drug therapy
Phytochemicals/*therapeutic use
Receptors, Tumor Necrosis Factor, Type I/*metabolism
Receptors, Tumor Necrosis Factor, Type II/*metabolism
Animals ; Inflammation/drug therapy ; Inflammation/metabolism ; Inflammation/pathology ; Neurodegenerative Diseases/metabolism ; Neurodegenerative Diseases/pathology
Czasopismo naukowe
Tytuł :
TNFα-Signaling Modulates the Kinase Activity of Human Effector Treg and Regulates IL-17A Expression.
Autorzy :
Urbano PCM; Laboratory Medical Immunology, Department of Laboratory Medicine, Radboud University Medical Center, Nijmegen, Netherlands.
He X; Laboratory Medical Immunology, Department of Laboratory Medicine, Radboud University Medical Center, Nijmegen, Netherlands.
van Heeswijk B; Laboratory Medical Immunology, Department of Laboratory Medicine, Radboud University Medical Center, Nijmegen, Netherlands.
Filho OPS; Department of Biochemistry, Radboud University Medical Center, Nijmegen, Netherlands.
Tijssen H; Laboratory Medical Immunology, Department of Laboratory Medicine, Radboud University Medical Center, Nijmegen, Netherlands.
Smeets RL; Laboratory Medical Immunology, Department of Laboratory Medicine, Radboud University Medical Center, Nijmegen, Netherlands.
Joosten I; Laboratory Medical Immunology, Department of Laboratory Medicine, Radboud University Medical Center, Nijmegen, Netherlands.
Koenen HJPM; Laboratory Medical Immunology, Department of Laboratory Medicine, Radboud University Medical Center, Nijmegen, Netherlands.
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Źródło :
Frontiers in immunology [Front Immunol] 2020 Jan 21; Vol. 10, pp. 3047. Date of Electronic Publication: 2020 Jan 21 (Print Publication: 2019).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Interleukin-17/*immunology
T-Lymphocytes, Regulatory/*immunology
Tumor Necrosis Factor alpha-Induced Protein 3/*immunology
Tumor Necrosis Factor-alpha/*immunology
Cells, Cultured ; Humans ; Interleukin-17/genetics ; Receptors, Tumor Necrosis Factor, Type II/genetics ; Receptors, Tumor Necrosis Factor, Type II/immunology ; Signal Transduction ; Tumor Necrosis Factor alpha-Induced Protein 3/genetics ; Tumor Necrosis Factor-alpha/genetics
Czasopismo naukowe

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