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Wyszukujesz frazę ""Nedergaard, M."" wg kryterium: Autor


Wyświetlanie 1-24 z 24
Tytuł :
Adrenergic receptor antagonism induces neuroprotection and facilitates recovery from acute ischemic stroke.
Autorzy :
Monai H; Laboratory for Neuron-Glia Circuitry, RIKEN Center for Brain Science, 351-0198 Wako, Saitama, Japan; .; Faculty of Core Research Natural Science Division, Ochanomizu University, 112-8610 Tokyo, Japan.
Wang X; Laboratory for Neuron-Glia Circuitry, RIKEN Center for Brain Science, 351-0198 Wako, Saitama, Japan.
Yahagi K; Laboratory for Neuron-Glia Circuitry, RIKEN Center for Brain Science, 351-0198 Wako, Saitama, Japan.
Lou N; Center for Translational Neuromedicine, University of Rochester Medical Center, Rochester, NY 14642.
Mestre H; Center for Translational Neuromedicine, University of Rochester Medical Center, Rochester, NY 14642.
Xu Q; Center for Translational Neuromedicine, University of Rochester Medical Center, Rochester, NY 14642.
Abe Y; Department of Pharmacology, School of Medicine, Keio University, 160-8582 Tokyo, Japan.
Yasui M; Department of Pharmacology, School of Medicine, Keio University, 160-8582 Tokyo, Japan.
Iwai Y; Laboratory for Neuron-Glia Circuitry, RIKEN Center for Brain Science, 351-0198 Wako, Saitama, Japan.
Nedergaard M; Center for Translational Neuromedicine, University of Rochester Medical Center, Rochester, NY 14642.; Center for Translational Neuromedicine, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.
Hirase H; Laboratory for Neuron-Glia Circuitry, RIKEN Center for Brain Science, 351-0198 Wako, Saitama, Japan; .; Center for Translational Neuromedicine, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.; Brain and Body System Science Institute, Saitama University, 338-8570 Saitama, Japan.
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2019 May 28; Vol. 116 (22), pp. 11010-11019. Date of Electronic Publication: 2019 May 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Adrenergic Antagonists/*pharmacology
Brain Ischemia/*metabolism
Neuroprotection/*drug effects
Stroke/*metabolism
Animals ; Aquaporin 4/metabolism ; Astrocytes/metabolism ; Disease Models, Animal ; Female ; Male ; Mice ; Mice, Inbred C57BL ; Potassium/metabolism
Czasopismo naukowe
Tytuł :
Purinergic receptor P2RY12-dependent microglial closure of the injured blood-brain barrier.
Autorzy :
Lou N; Center for Translational Neuromedicine, University of Rochester Medical School, Rochester, NY 14642;
Takano T; Center for Translational Neuromedicine, University of Rochester Medical School, Rochester, NY 14642;
Pei Y; Center for Translational Neuromedicine, University of Rochester Medical School, Rochester, NY 14642;
Xavier AL; Center for Translational Neuromedicine, University of Rochester Medical School, Rochester, NY 14642;
Goldman SA; Center for Translational Neuromedicine, University of Rochester Medical School, Rochester, NY 14642; Center for Translational Neuromedicine, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.
Nedergaard M; Center for Translational Neuromedicine, University of Rochester Medical School, Rochester, NY 14642; Center for Translational Neuromedicine, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark nedergaard@urmc.rochester.edu.
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2016 Jan 26; Vol. 113 (4), pp. 1074-9. Date of Electronic Publication: 2016 Jan 11.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Blood-Brain Barrier*
Microglia/*physiology
Receptors, Purinergic P2Y12/*physiology
Animals ; Cell Movement ; Clopidogrel ; Male ; Mice ; Mice, Inbred C57BL ; Microglia/drug effects ; Platelet Aggregation Inhibitors/pharmacology ; Ticlopidine/analogs & derivatives ; Ticlopidine/pharmacology
Czasopismo naukowe
Tytuł :
General anesthesia selectively disrupts astrocyte calcium signaling in the awake mouse cortex.
Autorzy :
Thrane AS; Division of Glial Disease and Therapeutics, Department of Neurosurgery, University of Rochester Medical Center, Rochester, NY 14642, USA. />Rangroo Thrane V
Zeppenfeld D
Lou N
Xu Q
Nagelhus EA
Nedergaard M
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2012 Nov 13; Vol. 109 (46), pp. 18974-9. Date of Electronic Publication: 2012 Oct 29.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Anesthesia, General*
Anesthetics/*pharmacology
Astrocytes/*metabolism
Calcium Signaling/*drug effects
Synapses/*metabolism
Wakefulness/*drug effects
Animals ; Inositol 1,4,5-Trisphosphate Receptors/metabolism ; Mice ; Mice, Knockout
Czasopismo naukowe
Tytuł :
Bergmann glia modulate cerebellar Purkinje cell bistability via Ca2+-dependent K+ uptake.
Autorzy :
Wang F; Division of Glial Disease and Therapeutics, Center for Translational Neuromedicine, University of Rochester, Rochester, NY 14642, USA. />Xu Q
Wang W
Takano T
Nedergaard M
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2012 May 15; Vol. 109 (20), pp. 7911-6. Date of Electronic Publication: 2012 Apr 30.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Calcium Signaling/*physiology
Cerebellum/*cytology
Membrane Potentials/*physiology
Neuroglia/*physiology
Potassium/*metabolism
Purkinje Cells/*metabolism
Action Potentials/physiology ; Animals ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Microelectrodes ; Microscopy, Confocal ; Purkinje Cells/cytology ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł :
Neuronal adenosine release, and not astrocytic ATP release, mediates feedback inhibition of excitatory activity.
Autorzy :
Lovatt D; Center for Translational Neuromedicine, Departments of Neurosurgery and Neurology, University of Rochester Medical Center, Rochester, NY 14642, USA.
Xu Q
Liu W
Takano T
Smith NA
Schnermann J
Tieu K
Nedergaard M
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2012 Apr 17; Vol. 109 (16), pp. 6265-70. Date of Electronic Publication: 2012 Mar 15.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Adenosine/*metabolism
Excitatory Postsynaptic Potentials/*physiology
Feedback, Physiological/*physiology
Neurons/*metabolism
5'-Nucleotidase/antagonists & inhibitors ; 5'-Nucleotidase/genetics ; 5'-Nucleotidase/metabolism ; Adenosine Diphosphate/analogs & derivatives ; Adenosine Diphosphate/pharmacology ; Adenosine Monophosphate/metabolism ; Adenosine Triphosphate/metabolism ; Animals ; Astrocytes/metabolism ; Brain/metabolism ; Brain/physiopathology ; CA1 Region, Hippocampal/cytology ; CA1 Region, Hippocampal/metabolism ; CA1 Region, Hippocampal/physiology ; GPI-Linked Proteins/antagonists & inhibitors ; GPI-Linked Proteins/genetics ; GPI-Linked Proteins/metabolism ; Long-Term Synaptic Depression/physiology ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Patch-Clamp Techniques ; Receptor, Adenosine A1/metabolism ; Seizures/metabolism ; Seizures/physiopathology
Czasopismo naukowe
Tytuł :
Critical role of aquaporin-4 (AQP4) in astrocytic Ca2+ signaling events elicited by cerebral edema.
Autorzy :
Thrane AS; Division of Glial Disease and Therapeutics, Center for Translational Neuromedicine, Department of Neurosurgery, University of Rochester Medical Center, Rochester, NY 14642, USA.
Rappold PM
Fujita T
Torres A
Bekar LK
Takano T
Peng W
Wang F
Rangroo Thrane V
Enger R
Haj-Yasein NN
Skare Ø
Holen T
Klungland A
Ottersen OP
Nedergaard M
Nagelhus EA
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2011 Jan 11; Vol. 108 (2), pp. 846-51. Date of Electronic Publication: 2010 Dec 27.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Aquaporin 4/*chemistry
Aquaporin 4/*genetics
Astrocytes/*metabolism
Brain Edema/*metabolism
Calcium/*metabolism
Adenosine Triphosphate/chemistry ; Animals ; Brain/pathology ; Edema/pathology ; Female ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Osmosis ; Photons ; Signal Transduction ; Water/chemistry
Czasopismo naukowe
Tytuł :
Systemic administration of an antagonist of the ATP-sensitive receptor P2X7 improves recovery after spinal cord injury.
Autorzy :
Peng W; Department of Neurosurgery, Division of Glial Disease and Therapeutics, Center for Translational Neuromedicine, University of Rochester Medical Center, Rochester, NY 14642, USA.
Cotrina ML
Han X
Yu H
Bekar L
Blum L
Takano T
Tian GF
Goldman SA
Nedergaard M
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2009 Jul 28; Vol. 106 (30), pp. 12489-93. Date of Electronic Publication: 2009 Jul 27.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Purinergic P2 Receptor Antagonists*
Adenosine Triphosphate/*metabolism
Rosaniline Dyes/*pharmacology
Spinal Cord Injuries/*prevention & control
Animals ; Disease Models, Animal ; Humans ; Indicators and Reagents/administration & dosage ; Indicators and Reagents/pharmacology ; Neuroprotective Agents/administration & dosage ; Neuroprotective Agents/pharmacology ; Rats ; Rats, Sprague-Dawley ; Receptors, Purinergic P2/metabolism ; Receptors, Purinergic P2X7 ; Recovery of Function/drug effects ; Rosaniline Dyes/administration & dosage ; Spinal Cord/drug effects ; Spinal Cord/metabolism ; Spinal Cord/pathology ; Spinal Cord Injuries/physiopathology ; Time Factors
Czasopismo naukowe
Tytuł :
Resolving vesicle fusion from lysis to monitor calcium-triggered lysosomal exocytosis in astrocytes.
Autorzy :
Jaiswal JK; The Rockefeller University, 1230 York Avenue, Box 304, New York, NY 10065, USA. />Fix M
Takano T
Nedergaard M
Simon SM
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2007 Aug 28; Vol. 104 (35), pp. 14151-6. Date of Electronic Publication: 2007 Aug 21.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Astrocytes/*physiology
Calcium/*physiology
Lysosomes/*physiology
Animals ; Astrocytes/cytology ; Exocytosis ; Lysosomes/ultrastructure ; Rats
Czasopismo naukowe
    Wyświetlanie 1-24 z 24

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