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Wyświetlanie 1-6 z 6
Tytuł:
Apolipoprotein A-I, elevated in trauma patients, inhibits platelet activation and decreases clot strength.
Autorzy:
Jones WL; Departments of Surgery, School of Medicine University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, USA.
Ramos CR; Departments of Surgery, School of Medicine University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, USA.
Banerjee A; Departments of Surgery, School of Medicine University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, USA.
Moore EE; Departments of Surgery, School of Medicine University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, USA.; Department of Surgery, Denver Health Medical Center, Denver, CO, USA.
Hansen KC; Department of Biochemistry/Molecular Genetics, School of Medicine University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, USA.
Coleman JR; Departments of Surgery, School of Medicine University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, USA.
Kelher M; Departments of Surgery, School of Medicine University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, USA.; Department of Bioengineering, School of Medicine University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, USA.
Neeves KB; Department of Pediatrics, School of Medicine University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, USA.; Vitalant Research Institute, Vitalant Mountain Division, Denver, CO, USA.
Silliman CC; Departments of Surgery, School of Medicine University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, USA.; Department of Bioengineering, School of Medicine University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, USA.; Department of Pediatrics, School of Medicine University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, USA.
Di Paola J; Department of Pediatrics, Division of Hematology/Oncology, Washington University School of Medicine, St. Louis, MO, USA.
Branchford B; Versiti Blood Research Institute, Hemostasis, Thrombosis, and Vascular Biology Program, Milwaukee, WI, USA.
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Źródło:
Platelets [Platelets] 2022 Nov 17; Vol. 33 (8), pp. 1119-1131. Date of Electronic Publication: 2022 Jun 05.
Typ publikacji:
Journal Article
MeSH Terms:
Pulmonary Embolism*
Thrombosis*
Animals ; Apolipoprotein A-I/metabolism ; Apolipoprotein A-I/pharmacology ; Arachidonic Acid/pharmacology ; Blood Platelets/metabolism ; CD36 Antigens/metabolism ; Humans ; Mice ; P-Selectin/metabolism ; Platelet Activation ; Platelet Aggregation ; Proto-Oncogene Proteins c-akt/metabolism
Czasopismo naukowe
Tytuł:
Multimodal microwheel swarms for targeting in three-dimensional networks.
Autorzy:
Zimmermann CJ; Department of Chemical and Biological Engineering, Colorado School of Mines, Golden, CO, USA.
Herson PS; Department of Anesthesiology, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, USA.
Neeves KB; Department of Bioengineering, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, USA.; Department of Pediatrics, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, USA.
Marr DWM; Department of Chemical and Biological Engineering, Colorado School of Mines, Golden, CO, USA. .
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Źródło:
Scientific reports [Sci Rep] 2022 Mar 24; Vol. 12 (1), pp. 5078. Date of Electronic Publication: 2022 Mar 24.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Drug Delivery Systems*
Magnetic Fields*
Czasopismo naukowe
Tytuł:
A local and global sensitivity analysis of a mathematical model of coagulation and platelet deposition under flow.
Autorzy:
Link KG; Department of Bioengineering, University of Utah, Salt Lake City, UT, United States of America.
Stobb MT; Department of Applied Mathematics, University of California Merced, Merced, CA, United States of America.
Di Paola J; Department of Pediatrics, University of Colorado School of Medicine, Aurora, CO, United States of America.
Neeves KB; Department of Pediatrics, University of Colorado School of Medicine, Aurora, CO, United States of America.; Department of Chemical and Biological Engineering, Colorado School of Mines, Golden, CO, United States of America.
Fogelson AL; Department of Mathematics, University of Utah, Salt Lake City, UT, United States of America.; Department of Bioengineering, University of Utah, Salt Lake City, UT, United States of America.
Sindi SS; Department of Applied Mathematics, University of California Merced, Merced, CA, United States of America.
Leiderman K; Department of Applied Mathematics and Statistics, Colorado School of Mines, Golden, CO, United States of America.
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Źródło:
PloS one [PLoS One] 2018 Jul 26; Vol. 13 (7), pp. e0200917. Date of Electronic Publication: 2018 Jul 26 (Print Publication: 2018).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Blood Coagulation*
Hemostasis*
Models, Biological*
Blood Platelets/*physiology
Kinetics ; Platelet Aggregation ; Uncertainty
Czasopismo naukowe
Tytuł:
Flow chamber and microfluidic approaches for measuring thrombus formation in genetic bleeding disorders.
Autorzy:
Schoeman RM; a Chemical and Biological Engineering Department , Colorado School of Mines , Golden , CO , USA.
Lehmann M; a Chemical and Biological Engineering Department , Colorado School of Mines , Golden , CO , USA.
Neeves KB; a Chemical and Biological Engineering Department , Colorado School of Mines , Golden , CO , USA.; b Pediatrics, University of Colorado , Denver , CO , USA.
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Źródło:
Platelets [Platelets] 2017 Jul; Vol. 28 (5), pp. 463-471. Date of Electronic Publication: 2017 May 22.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Lab-On-A-Chip Devices*
Genetic Diseases, Inborn/*metabolism
Hemorrhage/*metabolism
Microfluidic Analytical Techniques/*methods
Thrombosis/*metabolism
Animals ; Genetic Diseases, Inborn/genetics ; Genetic Diseases, Inborn/pathology ; Genetic Diseases, Inborn/physiopathology ; Hemorrhage/genetics ; Hemorrhage/pathology ; Hemorrhage/physiopathology ; Humans ; Thrombosis/genetics ; Thrombosis/pathology ; Thrombosis/physiopathology
Czasopismo naukowe
Tytuł:
The effect of factor VIII deficiencies and replacement and bypass therapies on thrombus formation under venous flow conditions in microfluidic and computational models.
Autorzy:
Onasoga-Jarvis AA; Department of Chemical and Biological Engineering, Colorado School of Mines, Golden, Colorado, United States of America.
Leiderman K
Fogelson AL
Wang M
Manco-Johnson MJ
Di Paola JA
Neeves KB
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Źródło:
PloS one [PLoS One] 2013 Nov 13; Vol. 8 (11), pp. e78732. Date of Electronic Publication: 2013 Nov 13 (Print Publication: 2013).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Hemophilia A/*drug therapy
Thrombosis/*physiopathology
Adolescent ; Biomechanical Phenomena ; Blood Coagulation ; Child, Preschool ; Computer Simulation ; Cysteine Endopeptidases/physiology ; Factor VIII/therapeutic use ; Factor VIIa/physiology ; Fibrin/metabolism ; Fibrin/ultrastructure ; Hemophilia A/physiopathology ; Humans ; Male ; Microfluidics ; Models, Biological ; Neoplasm Proteins/physiology ; Phenotype ; Platelet Aggregation ; Regional Blood Flow ; Thromboplastin/physiology ; Young Adult
Czasopismo naukowe
Tytuł:
Sources of variability in platelet accumulation on type 1 fibrillar collagen in microfluidic flow assays.
Autorzy:
Neeves KB; Department of Chemical and Biological Engineering, Colorado School of Mines, Golden, Colorado, United States of America. />Onasoga AA
Hansen RR
Lilly JJ
Venckunaite D
Sumner MB
Irish AT
Brodsky G
Manco-Johnson MJ
Di Paola JA
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Źródło:
PloS one [PLoS One] 2013; Vol. 8 (1), pp. e54680. Date of Electronic Publication: 2013 Jan 23.
Typ publikacji:
Clinical Trial; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Blood Platelets/*cytology
Blood Platelets/*metabolism
Collagen Type I/*chemistry
Microfluidic Analytical Techniques/*methods
Microfluidic Analytical Techniques/*standards
Adult ; Animals ; Female ; Horses ; Humans ; Male ; Mice ; Observer Variation ; Platelet Function Tests/methods ; Reproducibility of Results
Czasopismo naukowe
    Wyświetlanie 1-6 z 6

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