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Wyświetlanie 1-20 z 236
Tytuł:
Ultraviolet radiation-induced apoptosis is mediated by Daxx.
Autorzy:
Wu S; Department of Radiation Oncology, Division of Radiation and Cancer Biology, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
Loke HN
Rehemtulla A
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Źródło:
Neoplasia (New York, N.Y.) [Neoplasia] 2002 Nov-Dec; Vol. 4 (6), pp. 486-92.
Typ publikacji:
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:
Intracellular Signaling Peptides and Proteins*
Apoptosis/*radiation effects
Carrier Proteins/*metabolism
Mitogen-Activated Protein Kinases/*metabolism
Nuclear Proteins/*metabolism
Proto-Oncogene Proteins c-jun/*metabolism
Adaptor Proteins, Signal Transducing ; Carrier Proteins/genetics ; Cells, Cultured ; Co-Repressor Proteins ; Coenzyme A Ligases/genetics ; Coenzyme A Ligases/metabolism ; DNA Primers/chemistry ; Escherichia coli Proteins/genetics ; Escherichia coli Proteins/metabolism ; Green Fluorescent Proteins ; Humans ; Immunoblotting ; JNK Mitogen-Activated Protein Kinases ; Kidney/metabolism ; Kidney/radiation effects ; Luminescent Proteins/metabolism ; Molecular Chaperones ; Mutagenesis/physiology ; Nuclear Proteins/genetics ; Phosphorylation ; Plasmids ; Polymerase Chain Reaction ; Proto-Oncogene Mas ; Signal Transduction/physiology ; Transfection ; Ultraviolet Rays ; fas Receptor/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
DNA amplification by breakage/fusion/bridge cycles initiated by spontaneous telomere loss in a human cancer cell line.
Autorzy:
Lo AW; Radiation Oncology Research Laboratory, University of California, 1855 Folsom Street, MCB 200, San Francisco, CA 94103, USA.
Sabatier L
Fouladi B
Pottier G
Ricoul M
Murnane JP
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Źródło:
Neoplasia (New York, N.Y.) [Neoplasia] 2002 Nov-Dec; Vol. 4 (6), pp. 531-8.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:
Chromosome Breakage/*genetics
Chromosomes, Human, Pair 16/*genetics
DNA, Neoplasm/*genetics
Telomere/*genetics
Urinary Bladder Neoplasms/*genetics
Anaphase/genetics ; Blotting, Southern ; Chromosome Aberrations ; DNA Damage ; Gene Amplification ; Herpesvirus 1, Human/genetics ; Herpesvirus 1, Human/metabolism ; Humans ; In Situ Hybridization, Fluorescence ; Karyotyping ; Plasmids/genetics ; Telomere/metabolism ; Thymidine Kinase/genetics ; Transfection ; Tumor Cells, Cultured/physiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
MRI of mouse models for gliomas shows similarities to humans and can be used to identify mice for preclinical trials.
Autorzy:
Koutcher JA; Department of Medical Physics, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA. />Hu X
Xu S
Gade TP
Leeds N
Zhou XJ
Zagzag D
Holland EC
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Źródło:
Neoplasia (New York, N.Y.) [Neoplasia] 2002 Nov-Dec; Vol. 4 (6), pp. 480-5.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:
Protein Serine-Threonine Kinases*
Brain Neoplasms/*diagnosis
Glioblastoma/*diagnosis
Magnetic Resonance Imaging/*methods
Animals ; Brain Neoplasms/diagnostic imaging ; Brain Neoplasms/pathology ; Disease Models, Animal ; ErbB Receptors/genetics ; ErbB Receptors/metabolism ; Gadolinium DTPA ; Glioblastoma/diagnostic imaging ; Glioblastoma/pathology ; Humans ; Mice ; Mice, Transgenic ; Proto-Oncogene Proteins/metabolism ; Proto-Oncogene Proteins c-akt ; Radiography ; Retroviridae/genetics ; ras Proteins/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Detection of spontaneous schwannomas by MRI in a transgenic murine model of neurofibromatosis type 2.
Autorzy:
Messerli SM; Molecular Neurogenetics Unit, Department of Neurology, Massachusetts General Hospital and Neuroscience Program, Harvard Medical School, Charlestown, MA 02129, USA.
Tang Y
Giovannini M
Bronson R
Weissleder R
Breakefield XO
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Źródło:
Neoplasia (New York, N.Y.) [Neoplasia] 2002 Nov-Dec; Vol. 4 (6), pp. 501-9.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:
Disease Models, Animal*
Magnetic Resonance Imaging/*methods
Neurilemmoma/*diagnosis
Neurofibromatosis 2/*diagnosis
Animals ; Biomarkers, Tumor/metabolism ; Female ; Herpes Simplex/pathology ; Humans ; Immunoenzyme Techniques ; Male ; Mice ; Mice, Transgenic ; Neurilemmoma/metabolism ; Neurilemmoma/virology ; Neurofibromatosis 2/genetics ; Neurofibromin 2/genetics ; Neurofibromin 2/metabolism ; S100 Proteins/genetics ; S100 Proteins/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
A mortality gene(s) for the human adenocarcinoma line HeLa maps to a 130-kb region of human chromosome 4q22-q23.
Autorzy:
Bryce SD; Beatson Institute for Cancer Research, Cancer Research UK Beatson Laboratories, Garscube Estate, Switchback Road, Bearsden, Glasgow G61 1BD, Scotland, UK.
Morrison V
Craig NJ
Forsyth NR
Fitzsimmons SA
Ireland H
Cuthbert AP
Newbold RF
Parkinson EK
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Źródło:
Neoplasia (New York, N.Y.) [Neoplasia] 2002 Nov-Dec; Vol. 4 (6), pp. 544-50.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Chromosome Mapping*
Chromosomes, Human, Pair 4/*genetics
Transcription Factors/*genetics
Alleles ; Animals ; Cellular Senescence/genetics ; Chromosome Painting ; Chromosomes, Human, Pair 4/metabolism ; Clone Cells ; Genes, Tumor Suppressor ; Genetic Complementation Test ; Genotype ; HeLa Cells/metabolism ; Humans ; Loss of Heterozygosity ; Mice ; Microsatellite Repeats ; Phenotype ; Polymorphism, Genetic ; Transcription Factors/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Enhanced uptake of ifosfamide into GH3 prolactinomas with hypercapnic hyperoxic gases monitored in vivo by (31)P MRS.
Autorzy:
Rodrigues LM; CR UK Biomedical Magnetic Resonance Research Group, Department of Biochemistry and Immunology, St. George's Hospital Medical School, Cranmer Terrace, London SW17 ORE, UK. />Robinson SP
McSheehy PM
Stubbs M
Griffiths JR
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Źródło:
Neoplasia (New York, N.Y.) [Neoplasia] 2002 Nov-Dec; Vol. 4 (6), pp. 539-43.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Magnetic Resonance Spectroscopy*
Antineoplastic Agents, Alkylating/*pharmacokinetics
Hypercapnia/*metabolism
Hyperoxia/*metabolism
Ifosfamide/*pharmacokinetics
Pituitary Neoplasms/*metabolism
Prolactinoma/*metabolism
Animals ; Carbon Dioxide/administration & dosage ; Female ; Oxygen/administration & dosage ; Phosphorus/metabolism ; Phosphorus Isotopes/pharmacokinetics ; Pituitary Neoplasms/drug therapy ; Prolactinoma/drug therapy ; Rats ; Rats, Wistar ; Tissue Distribution
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Defining characteristics of Types I and II apoptotic cells in response to TRAIL.
Autorzy:
Ozören N; Laboratory of Molecular Oncology and Cell Cycle Regulation, Howard Hughes Medical Institute, Philadelphia, PA 19104, USA.
El-Deiry WS
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Źródło:
Neoplasia (New York, N.Y.) [Neoplasia] 2002 Nov-Dec; Vol. 4 (6), pp. 551-7.
Typ publikacji:
Journal Article
MeSH Terms:
Arabidopsis Proteins*
Intracellular Signaling Peptides and Proteins*
Adenocarcinoma/*metabolism
Apoptosis/*drug effects
Carcinoma, Non-Small-Cell Lung/*metabolism
Carrier Proteins/*metabolism
Hepatocytes/*enzymology
Lung Neoplasms/*metabolism
Membrane Glycoproteins/*pharmacology
Mitochondria/*physiology
Tumor Necrosis Factor-alpha/*pharmacology
Adenocarcinoma/enzymology ; Adenocarcinoma/pathology ; Apoptosis Regulatory Proteins ; BH3 Interacting Domain Death Agonist Protein ; Blotting, Western ; CASP8 and FADD-Like Apoptosis Regulating Protein ; Carcinoma, Non-Small-Cell Lung/enzymology ; Carcinoma, Non-Small-Cell Lung/pathology ; Caspase 3 ; Caspase 8 ; Caspase 9 ; Caspases/metabolism ; Child ; Colonic Neoplasms/drug therapy ; Colonic Neoplasms/enzymology ; Colonic Neoplasms/pathology ; Cytochrome c Group/metabolism ; Enzyme Precursors/metabolism ; Fatty Acid Desaturases/metabolism ; HSP70 Heat-Shock Proteins/metabolism ; Hepatocytes/cytology ; Humans ; Lung Neoplasms/enzymology ; Lung Neoplasms/pathology ; Male ; Poly(ADP-ribose) Polymerases/metabolism ; Precipitin Tests ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Subcellular Fractions ; TNF-Related Apoptosis-Inducing Ligand ; Tumor Cells, Cultured
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
The hypercoagulable state of malignancy: pathogenesis and current debate.
Autorzy:
Caine GJ; Hemostasis, Thrombosis and Vascular Biology Unit, University Department of Medicine, City Hospital, Birmingham B18 7QH, UK. />Stonelake PS
Lip GY
Kehoe ST
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Źródło:
Neoplasia (New York, N.Y.) [Neoplasia] 2002 Nov-Dec; Vol. 4 (6), pp. 465-73.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Blood Coagulation*
Neoplasms/*complications
Thrombophilia/*etiology
Antineoplastic Agents/therapeutic use ; Blood Coagulation Factors/metabolism ; Cell Communication ; Cytokines/metabolism ; Humans ; Neoplasms/drug therapy ; Thrombophilia/therapy
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Cooperation of hTERT, SV40 T antigen and oncogenic Ras in tumorigenesis: a cell transplantation model using bovine adrenocortical cells.
Autorzy:
Thomas M; Huffington Center on Aging, Baylor College of Medicine, 1 Baylor Plaza, Houston, TX 77030, USA.
Suwa T
Yang L
Zhao L
Hawks CL
Hornsby PJ
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Źródło:
Neoplasia (New York, N.Y.) [Neoplasia] 2002 Nov-Dec; Vol. 4 (6), pp. 493-500.
Typ publikacji:
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:
Adrenal Cortex/*cytology
Antigens, Polyomavirus Transforming/*physiology
Cell Transformation, Neoplastic/*pathology
Kidney Neoplasms/*pathology
Proto-Oncogene Proteins p21(ras)/*physiology
Telomerase/*physiology
Adrenal Cortex/metabolism ; Adrenal Cortex/transplantation ; Animals ; Blotting, Western ; Cattle ; Cell Transformation, Neoplastic/metabolism ; Cell Transformation, Viral/genetics ; Cell Transplantation ; Cells, Cultured/pathology ; DNA-Binding Proteins ; Female ; Humans ; Immunoenzyme Techniques ; Kidney Neoplasms/metabolism ; Male ; Mice ; Mice, SCID ; Models, Biological ; Transfection
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Functional inactivation of pRB results in aneuploid mammalian cells after release from a mitotic block.
Autorzy:
Lentini L; Department of Cell and Developmental Biology A. Monroy, University of Palermo, viale delle Scienze 90128, Palermo, Italy.
Pipitone L
Di Leonardo A
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Źródło:
Neoplasia (New York, N.Y.) [Neoplasia] 2002 Sep-Oct; Vol. 4 (5), pp. 380-7.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Aneuploidy*
DNA Replication/*drug effects
Fibroblasts/*drug effects
Genes, Retinoblastoma/*physiology
Animals ; Antineoplastic Agents, Phytogenic/pharmacology ; Cell Cycle/drug effects ; Cell Transformation, Neoplastic ; Cells, Cultured ; Chromosome Fragility ; Colony-Forming Units Assay ; Demecolcine/pharmacology ; Female ; Fibroblasts/cytology ; Flow Cytometry ; Humans ; In Situ Hybridization, Fluorescence ; Mice/embryology ; Microscopy, Fluorescence ; Mitosis/genetics ; Retinoblastoma Protein/deficiency ; Spindle Apparatus/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Prostate cancer aggressiveness locus on chromosome 7q32-q33 identified by linkage and allelic imbalance studies.
Autorzy:
Neville PJ; Department of Cancer Biology, Cleveland Clinic Foundation, Cleveland, OH 44195, USA.
Conti DV
Paris PL
Levin H
Catalona WJ
Suarez BK
Witte JS
Casey G
Pokaż więcej
Źródło:
Neoplasia (New York, N.Y.) [Neoplasia] 2002 Sep-Oct; Vol. 4 (5), pp. 424-31.
Typ publikacji:
Journal Article
MeSH Terms:
Allelic Imbalance/*genetics
Chromosomes, Human, Pair 7/*genetics
Genetic Linkage/*genetics
Genetic Predisposition to Disease/*genetics
Prostatic Neoplasms/*genetics
Aged ; DNA, Neoplasm/genetics ; Humans ; Male ; Microsatellite Repeats ; Middle Aged ; Neoplasm Staging ; Radiation Hybrid Mapping
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Antibody-directed effector cell therapy of tumors: analysis and optimization using a physiologically based pharmacokinetic model.
Autorzy:
Friedrich SW; Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.
Lin SC
Stoll BR
Baxter LT
Munn LL
Jain RK
Pokaż więcej
Źródło:
Neoplasia (New York, N.Y.) [Neoplasia] 2002 Sep-Oct; Vol. 4 (5), pp. 449-63.
Typ publikacji:
Journal Article; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:
Immunotherapy*
Antibodies, Bispecific/*pharmacokinetics
CD3 Complex/*immunology
Neoplasms/*metabolism
Neoplasms/*therapy
Animals ; Antibodies, Bispecific/therapeutic use ; Antibodies, Neoplasm/immunology ; Cytotoxicity, Immunologic ; Humans ; Lymphocyte Activation/drug effects ; Lymphocytes ; Models, Biological ; Neoplasm Proteins/immunology ; Neoplasm Proteins/metabolism ; Organ Specificity ; Species Specificity
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Mutational analysis of DBD*--a unique antileukemic gene sequence.
Autorzy:
Ji YS; Department of Human Biological Chemistry and Genetics, The University of Texas Medical Branch, Galveston, TX 77555-0645, USA.
Johnson BH
Webb MS
Thompson EB
Pokaż więcej
Źródło:
Neoplasia (New York, N.Y.) [Neoplasia] 2002 Sep-Oct; Vol. 4 (5), pp. 417-23.
Typ publikacji:
Journal Article; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:
Mutation*
DNA, Neoplasm/*genetics
DNA-Binding Proteins/*genetics
Leukemia, Experimental/*genetics
Receptors, Glucocorticoid/*genetics
Amino Acid Sequence ; Apoptosis ; Binding Sites ; DNA Mutational Analysis ; Humans ; Leukemia, Experimental/pathology ; Molecular Sequence Data ; Mutagenesis, Site-Directed ; Transfection ; Tumor Cells, Cultured/pathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Exposure of human breast cancer cells to the anti-inflammatory agent indomethacin alters choline phospholipid metabolites and Nm23 expression.
Autorzy:
Natarajan K; Department of Radiology, MR Oncology Section, Division of MR Research, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Mori N
Artemov D
Bhujwalla ZM
Pokaż więcej
Źródło:
Neoplasia (New York, N.Y.) [Neoplasia] 2002 Sep-Oct; Vol. 4 (5), pp. 409-16.
Typ publikacji:
Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:
Nucleoside-Diphosphate Kinase*
Anti-Inflammatory Agents, Non-Steroidal/*pharmacology
Breast Neoplasms/*drug therapy
Choline/*metabolism
Glycerylphosphorylcholine/*metabolism
Indomethacin/*pharmacology
Monomeric GTP-Binding Proteins/*metabolism
Phosphorylcholine/*metabolism
Transcription Factors/*metabolism
Blotting, Western ; Breast Neoplasms/metabolism ; Cell Division/drug effects ; Cyclooxygenase 1 ; Cyclooxygenase 2 ; Epithelial Cells/metabolism ; Female ; Humans ; Isoenzymes/metabolism ; Magnetic Resonance Spectroscopy ; Membrane Proteins ; NM23 Nucleoside Diphosphate Kinases ; Prostaglandin-Endoperoxide Synthases/metabolism ; Tumor Cells, Cultured
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Suppression of tumor recurrence and metastasis by a combination of the PHSCN sequence and the antiangiogenic compound tetrathiomolybdate in prostate carcinoma.
Autorzy:
van Golen KL; Department of Internal Medicine, Division of Hematology and Oncology, University of Michigan Comprehensive Cancer Center, Ann Arbor, MI 48109-0948, USA. />Bao L
Brewer GJ
Pienta KJ
Kamradt JM
Livant DL
Merajver SD
Pokaż więcej
Źródło:
Neoplasia (New York, N.Y.) [Neoplasia] 2002 Sep-Oct; Vol. 4 (5), pp. 373-9.
Typ publikacji:
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:
Adenocarcinoma/*drug therapy
Angiogenesis Inhibitors/*therapeutic use
Lung Neoplasms/*drug therapy
Molybdenum/*therapeutic use
Neoplasm Recurrence, Local/*prevention & control
Neovascularization, Pathologic/*drug therapy
Oligopeptides/*therapeutic use
Prostatic Neoplasms/*drug therapy
Adenocarcinoma/metabolism ; Adenocarcinoma/secondary ; Animals ; Copper/deficiency ; Disease Models, Animal ; Drug Therapy, Combination ; Humans ; Lung Neoplasms/blood supply ; Lung Neoplasms/secondary ; Male ; Mice ; Mice, Nude ; Neoplasm Recurrence, Local/therapy ; Neoplasm Transplantation ; Prostatic Neoplasms/blood supply ; Prostatic Neoplasms/pathology ; Rats ; Tumor Cells, Cultured
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
IL-13Ralpha2 is a glioma-restricted receptor for interleukin-13.
Autorzy:
Mintz A; Section of Neurosurgery/H110, Pennsylvania State University College of Medicine, 500 University Drive, Hershey, PA 17033-0850, USA.
Gibo DM
Slagle-Webb B
Christensen ND
Debinski W
Pokaż więcej
Źródło:
Neoplasia (New York, N.Y.) [Neoplasia] 2002 Sep-Oct; Vol. 4 (5), pp. 388-99.
Typ publikacji:
Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:
Brain Neoplasms/*metabolism
Glioma/*metabolism
Interleukin-13/*metabolism
Receptors, Interleukin/*metabolism
Animals ; Binding Sites ; Blotting, Northern ; Brain Neoplasms/pathology ; CHO Cells/metabolism ; Cricetinae ; DNA Primers/chemistry ; DNA, Antisense/pharmacology ; Enzyme-Linked Immunosorbent Assay ; Flow Cytometry ; Glioma/pathology ; Humans ; Interleukin-13 Receptor alpha1 Subunit ; Interleukin-4/metabolism ; Polymerase Chain Reaction ; Protein Binding ; RNA/metabolism ; Receptors, Interleukin/genetics ; Receptors, Interleukin-13 ; Transfection ; Tumor Cells, Cultured
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Wyświetlanie 1-20 z 236

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