Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Wyszukujesz frazę ""Neoplasm Invasiveness"" wg kryterium: Temat


Starter badań:

Tytuł:
c-Src-mediated phosphorylation and activation of kinesin KIF1C promotes elongation of invadopodia in cancer cells.
Autorzy:
Saji T; Department of Biochemistry, Fukushima Medical University School of Medicine, Fukushima, Japan; Division of Cell Physiology, Department of Physiology and Cell Biology, Graduate School of Medicine, Kobe University, Kobe, Japan.
Nishita M; Department of Biochemistry, Fukushima Medical University School of Medicine, Fukushima, Japan; Division of Cell Physiology, Department of Physiology and Cell Biology, Graduate School of Medicine, Kobe University, Kobe, Japan. Electronic address: .
Ikeda K; Department of Cell Biology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Endo M; Division of Cell Physiology, Department of Physiology and Cell Biology, Graduate School of Medicine, Kobe University, Kobe, Japan.
Okada Y; Department of Cell Biology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan; Laboratory for Cell Polarity Regulation, RIKEN Center for Biosystems Dynamics Research (BDR), Osaka, Japan; Department of Physics, Graduate School of Science, The University of Tokyo, Tokyo, Japan; Universal Biology Institute (UBI) and International Research Center for Neurointelligence (WPI-IRCN), The University of Tokyo, Tokyo, Japan.
Minami Y; Division of Cell Physiology, Department of Physiology and Cell Biology, Graduate School of Medicine, Kobe University, Kobe, Japan. Electronic address: .
Pokaż więcej
Źródło:
The Journal of biological chemistry [J Biol Chem] 2022 Jul; Vol. 298 (7), pp. 102090. Date of Electronic Publication: 2022 May 30.
Typ publikacji:
Journal Article
MeSH Terms:
Genes, src*
Kinesins*/genetics
Neoplasm Invasiveness*
Podosomes*/metabolism
Cell Line, Tumor ; Humans ; Microtubules/metabolism ; Phosphorylation ; Protein Tyrosine Phosphatases, Non-Receptor ; Tyrosine/metabolism
Czasopismo naukowe
Tytuł:
The Functions of PCNA in Tumor Stemness and Invasion.
Autorzy:
Wang YL; Graduate Institute of Biomedical Sciences, College of Medicine, China Medical University, Taichung 40402, Taiwan.; Center for Molecular Medicine, China Medical University Hospital, Taichung 40447, Taiwan.
Wu WR; Graduate Institute of Biomedical Sciences, College of Medicine, China Medical University, Taichung 40402, Taiwan.
Lin PL; Graduate Institute of Biomedical Sciences, College of Medicine, China Medical University, Taichung 40402, Taiwan.
Shen YC; Graduate Institute of Biomedical Sciences, College of Medicine, China Medical University, Taichung 40402, Taiwan.; Center for Molecular Medicine, China Medical University Hospital, Taichung 40447, Taiwan.
Lin YZ; Graduate Institute of Biomedical Sciences, College of Medicine, China Medical University, Taichung 40402, Taiwan.
Li HW; Research Center for Cancer Biology, China Medical University, Taichung 40402, Taiwan.
Hsu KW; Research Center for Cancer Biology, China Medical University, Taichung 40402, Taiwan.; Institute of Translational Medicine and New Drug Development, China Medical University, Taichung 40402, Taiwan.; Drug Development Center, China Medical University, Taichung 40402, Taiwan.
Wang SC; Graduate Institute of Biomedical Sciences, College of Medicine, China Medical University, Taichung 40402, Taiwan.; Center for Molecular Medicine, China Medical University Hospital, Taichung 40447, Taiwan.; Research Center for Cancer Biology, China Medical University, Taichung 40402, Taiwan.; Cancer Biology and Drug Discovery Ph.D. Program, China Medical University, Taichung 40402, Taiwan.; Department of Biotechnology, Asia University, Taichung 41354, Taiwan.; Department of Cancer Biology, University of Cincinnati, Cincinnati, OH 45267, USA.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 May 19; Vol. 23 (10). Date of Electronic Publication: 2022 May 19.
Typ publikacji:
Journal Article
MeSH Terms:
Neoplasm Invasiveness*
Neoplasms*
Neoplastic Stem Cells*
Proliferating Cell Nuclear Antigen*/genetics
Proliferating Cell Nuclear Antigen*/metabolism
Animals ; Cell Proliferation ; DNA Replication ; Mice ; Phosphorylation
Czasopismo naukowe
Tytuł:
Parenchymal Volume Replacement by Renal Cell Carcinoma Prior to Intervention: Predictive Factors and Functional Implications.
Autorzy:
Palacios DA; Center for Urologic Oncology, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH.
Campbell RA; Center for Urologic Oncology, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH.
Yasuda Y; Center for Urologic Oncology, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH.
Roversia G; Center for Urologic Oncology, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH.
Munoz-Lopez C; Center for Urologic Oncology, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH.
Abramczyk E; Center for Urologic Oncology, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH.
Kelly M; Center for Urologic Oncology, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH.
Caraballo ER; Center for Urologic Oncology, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH.
Suk-Ouichai C; Center for Urologic Oncology, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH; Division of Urology, Department of Surgery, Siriraj Hospital, Mahidol University, BKK, Bangkok, Thailand.
Lin L; Center for Urologic Oncology, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH.
Weight C; Center for Urologic Oncology, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH.
Abouassaly R; Center for Urologic Oncology, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH.
Campbell SC; Center for Urologic Oncology, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH. Electronic address: .
Pokaż więcej
Źródło:
Urology [Urology] 2022 Jan; Vol. 159, pp. 139-145. Date of Electronic Publication: 2021 Oct 02.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Renal Cell*/pathology
Carcinoma, Renal Cell*/physiopathology
Carcinoma, Renal Cell*/surgery
Kidney*/diagnostic imaging
Kidney*/physiopathology
Kidney Neoplasms*/pathology
Kidney Neoplasms*/physiopathology
Kidney Neoplasms*/surgery
Neoplasm Invasiveness*/diagnostic imaging
Neoplasm Invasiveness*/pathology
Neoplasm Invasiveness*/physiopathology
Nephrectomy*/adverse effects
Nephrectomy*/methods
Parenchymal Tissue*/diagnostic imaging
Parenchymal Tissue*/pathology
Preoperative Care*/methods
Preoperative Care*/statistics & numerical data
Female ; Humans ; Kidney Function Tests/methods ; Male ; Middle Aged ; Neoplasm Staging ; Organ Size ; Prognosis ; Renal Insufficiency/diagnosis ; Renal Insufficiency/etiology ; Tomography, X-Ray Computed/methods ; Tumor Burden
Czasopismo naukowe
Tytuł:
Identification of Rad51 as a prognostic biomarker correlated with immune infiltration in hepatocellular carcinoma.
Autorzy:
Xu H; Yangzhou University Medical College, Yangzhou, Jiangsu, P.R. China.
Xiong C; Dalian Medical University, Dalian, Liaoning, P.R. China.
Chen Y; Yangzhou University Medical College, Yangzhou, Jiangsu, P.R. China.
Zhang C; Department of Hepatobiliary Surgery, Clinical Medical College, Yangzhou University, Yangzhou, Jiangsu, P.R. China.
Bai D; Department of Hepatobiliary Surgery, Clinical Medical College, Yangzhou University, Yangzhou, Jiangsu, P.R. China.
Pokaż więcej
Źródło:
Bioengineered [Bioengineered] 2021 Dec; Vol. 12 (1), pp. 2664-2675.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Carcinoma, Hepatocellular*/diagnosis
Carcinoma, Hepatocellular*/genetics
Carcinoma, Hepatocellular*/mortality
Carcinoma, Hepatocellular*/pathology
Liver Neoplasms*/diagnosis
Liver Neoplasms*/genetics
Liver Neoplasms*/mortality
Liver Neoplasms*/pathology
Neoplasm Invasiveness*/genetics
Neoplasm Invasiveness*/pathology
Rad51 Recombinase/*genetics
Biomarkers, Tumor/genetics ; Biomarkers, Tumor/metabolism ; DNA Repair/genetics ; Databases, Genetic ; Female ; Humans ; Liver/metabolism ; Liver/pathology ; Male ; Prognosis ; Rad51 Recombinase/metabolism
Czasopismo naukowe
Tytuł:
CRISPR/Cas9 Mediated Knockout of Cyclooxygenase-2 Gene Inhibits Invasiveness in A2058 Melanoma Cells.
Autorzy:
Haase-Kohn C; Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Department of Radiopharmaceutical and Chemical Biology, Institute of Radiopharmaceutical Cancer Research, 01328 Dresden, Germany.
Laube M; Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Department of Radiopharmaceutical and Chemical Biology, Institute of Radiopharmaceutical Cancer Research, 01328 Dresden, Germany.
Donat CK; Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Translational TME-Ligands, Institute of Radiopharmaceutical Cancer Research, 01328 Dresden, Germany.
Belter B; Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Department of Radiopharmaceutical and Chemical Biology, Institute of Radiopharmaceutical Cancer Research, 01328 Dresden, Germany.
Pietzsch J; Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Department of Radiopharmaceutical and Chemical Biology, Institute of Radiopharmaceutical Cancer Research, 01328 Dresden, Germany.; Faculty of Chemistry and Food Chemistry, School of Science, Technische Universität Dresden, 01069 Dresden, Germany.
Pokaż więcej
Źródło:
Cells [Cells] 2022 Feb 21; Vol. 11 (4). Date of Electronic Publication: 2022 Feb 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
CRISPR-Cas Systems*
Cyclooxygenase 2*/genetics
Melanoma*/pathology
Neoplasm Invasiveness*
Animals ; Cell Line, Tumor ; Gene Knockdown Techniques ; Humans ; Mice ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
GLIS1 in Cancer-Associated Fibroblasts Regulates the Migration and Invasion of Ovarian Cancer Cells.
Autorzy:
Kim MJ; Institute for Clinical Research, CHA Bundang Medical Center, CHA University, Seongnam 13496, Korea.
Jung D; Department of Pathology, CHA Bundang Medical Center, CHA University, Seongnam 13496, Korea.
Park JY; Institute for Clinical Research, CHA Bundang Medical Center, CHA University, Seongnam 13496, Korea.
Lee SM; Institute for Clinical Research, CHA Bundang Medical Center, CHA University, Seongnam 13496, Korea.
An HJ; Department of Pathology, CHA Bundang Medical Center, CHA University, Seongnam 13496, Korea.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Feb 17; Vol. 23 (4). Date of Electronic Publication: 2022 Feb 17.
Typ publikacji:
Journal Article
MeSH Terms:
Cancer-Associated Fibroblasts/*pathology
Cell Movement/*genetics
DNA-Binding Proteins/*genetics
Neoplasm Invasiveness/*genetics
Ovarian Neoplasms/*genetics
Transcription Factors/*genetics
Carcinoma, Ovarian Epithelial/genetics ; Carcinoma, Ovarian Epithelial/pathology ; Cell Line, Tumor ; Cell Proliferation/genetics ; Female ; Gene Expression Regulation, Neoplastic/genetics ; Humans ; MicroRNAs/genetics ; Neoplasm Invasiveness/pathology ; Ovarian Neoplasms/pathology ; Tumor Microenvironment/genetics
Czasopismo naukowe
Tytuł:
A computational modeling of invadopodia protrusion into an extracellular matrix fiber network.
Autorzy:
Kim MC; Departments of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA. .
Li R; Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.; Center for Systems Biology, Massachusetts General Hospital Research Institute, Boston, MA, 02114, USA.
Abeyaratne R; Departments of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
Kamm RD; Departments of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.; Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
Asada HH; Departments of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA. .
Pokaż więcej
Źródło:
Scientific reports [Sci Rep] 2022 Jan 24; Vol. 12 (1), pp. 1231. Date of Electronic Publication: 2022 Jan 24.
Typ publikacji:
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Models, Biological*
Neoplasm Invasiveness*
Neoplasms*
Microfilament Proteins/*physiology
Podosomes/*physiology
Cell Movement ; Extracellular Matrix ; Humans
Czasopismo naukowe
Tytuł:
WBP2 promotes BTRC mRNA stability to drive migration and invasion in triple-negative breast cancer via NF-κB activation.
Autorzy:
Lim YX; Integrative Sciences and Engineering Programme, National University of Singapore, Singapore.; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Lin H; Integrative Sciences and Engineering Programme, National University of Singapore, Singapore.; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Chu T; Integrative Sciences and Engineering Programme, National University of Singapore, Singapore.; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; Department of Biomedical Informatics, Yong Loo Lin School of Medicine, National University Health System, Singapore City, Singapore.
Lim YP; Integrative Sciences and Engineering Programme, National University of Singapore, Singapore.; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; National University Cancer Institute, Singapore City, Singapore.
Pokaż więcej
Źródło:
Molecular oncology [Mol Oncol] 2022 Jan; Vol. 16 (2), pp. 422-446. Date of Electronic Publication: 2021 Aug 12.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Neoplasm Invasiveness*
Neoplasm Metastasis*
NF-kappa B/*metabolism
RNA, Messenger/*genetics
Trans-Activators/*physiology
Triple Negative Breast Neoplasms/*pathology
beta-Transducin Repeat-Containing Proteins/*genetics
Cell Line, Tumor ; DNA Copy Number Variations ; Female ; Humans ; Inflammation/metabolism ; Triple Negative Breast Neoplasms/genetics ; Triple Negative Breast Neoplasms/metabolism
Czasopismo naukowe
Tytuł:
Effect of p53 and its N-terminally truncated isoform, Δ40p53, on breast cancer migration and invasion.
Autorzy:
Zhang X; Hunter Medical Research Institute, New Lambton Heights, NSW, Australia.; School of Biomedical Sciences and Pharmacy, College of Health, Medicine and Wellbeing, The University of Newcastle, NSW, Australia.
Groen K; Hunter Medical Research Institute, New Lambton Heights, NSW, Australia.; School of Biomedical Sciences and Pharmacy, College of Health, Medicine and Wellbeing, The University of Newcastle, NSW, Australia.
Morten BC; Hunter Medical Research Institute, New Lambton Heights, NSW, Australia.; School of Biomedical Sciences and Pharmacy, College of Health, Medicine and Wellbeing, The University of Newcastle, NSW, Australia.
Steffens Reinhardt L; Hunter Medical Research Institute, New Lambton Heights, NSW, Australia.; School of Biomedical Sciences and Pharmacy, College of Health, Medicine and Wellbeing, The University of Newcastle, NSW, Australia.
Campbell HG; Children's Medical Research Institute, University of Sydney, NSW, Australia.
Braithwaite AW; Children's Medical Research Institute, University of Sydney, NSW, Australia.; Department of Pathology, School of Medicine, University of Otago, Dunedin, New Zealand.
Bourdon JC; Dundee Cancer Centre, Ninewells Hospital and Medical School, University of Dundee, UK.
Avery-Kiejda KA; Hunter Medical Research Institute, New Lambton Heights, NSW, Australia.; School of Biomedical Sciences and Pharmacy, College of Health, Medicine and Wellbeing, The University of Newcastle, NSW, Australia.
Pokaż więcej
Źródło:
Molecular oncology [Mol Oncol] 2022 Jan; Vol. 16 (2), pp. 447-465. Date of Electronic Publication: 2021 Nov 23.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Neoplasm Invasiveness*
Neoplasm Metastasis*
Breast Neoplasms/*pathology
Protein Isoforms/*physiology
Tumor Suppressor Protein p53/*physiology
Breast Neoplasms/metabolism ; Cell Line, Tumor ; Cell Proliferation ; Female ; Gene Expression Profiling ; Gene Knockdown Techniques ; Humans ; Protein Isoforms/genetics ; Reverse Transcriptase Polymerase Chain Reaction ; Tumor Suppressor Protein p53/genetics
Czasopismo naukowe
Tytuł:
Ubiquitin-specific peptidase 39 promotes human glioma cells migration and invasion by facilitating ADAM9 mRNA maturation.
Autorzy:
Xiao Y; Guangdong Provincial Key Laboratory of Regional Immunity and Diseases, Department of Immunology, School of Medicine, Shenzhen University, China.
Ma W; Guangdong Provincial Key Laboratory of Regional Immunity and Diseases, Department of Immunology, School of Medicine, Shenzhen University, China.
Hu W; Department of Neurosurgery, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Di Q; Guangdong Provincial Key Laboratory of Regional Immunity and Diseases, Department of Immunology, School of Medicine, Shenzhen University, China.
Zhao X; Guangdong Provincial Key Laboratory of Regional Immunity and Diseases, Department of Immunology, School of Medicine, Shenzhen University, China.
Ma X; Guangdong Provincial Key Laboratory of Regional Immunity and Diseases, Department of Immunology, School of Medicine, Shenzhen University, China.
Chen X; Guangdong Provincial Key Laboratory of Regional Immunity and Diseases, Department of Immunology, School of Medicine, Shenzhen University, China.
Sun P; Guangdong Provincial Key Laboratory of Regional Immunity and Diseases, Department of Immunology, School of Medicine, Shenzhen University, China.
Wu H; Guangdong Provincial Key Laboratory of Regional Immunity and Diseases, Department of Immunology, School of Medicine, Shenzhen University, China.
Wu Z; Guangdong Provincial Key Laboratory of Regional Immunity and Diseases, Department of Immunology, School of Medicine, Shenzhen University, China.
Chen W; Guangdong Provincial Key Laboratory of Regional Immunity and Diseases, Department of Immunology, School of Medicine, Shenzhen University, China.
Pokaż więcej
Źródło:
Molecular oncology [Mol Oncol] 2022 Jan; Vol. 16 (2), pp. 388-404. Date of Electronic Publication: 2021 May 02.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cell Movement*
Neoplasm Invasiveness*
ADAM Proteins/*genetics
Brain Neoplasms/*pathology
Glioma/*pathology
Membrane Proteins/*genetics
RNA, Messenger/*genetics
Ubiquitin-Specific Proteases/*metabolism
Animals ; Brain Neoplasms/genetics ; Female ; Gene Knockdown Techniques ; Glioma/genetics ; Humans ; Mice ; Mice, Inbred C57BL ; Mice, Nude ; RNA, Small Interfering/genetics ; Ubiquitin-Specific Proteases/genetics
Czasopismo naukowe
Tytuł:
miR-10b-5p Suppresses the Proliferation and Invasion of Primary Hepatic Carcinoma Cells by Downregulating EphA2.
Autorzy:
Niu X; General Surgery, Luhe Hospital, Capital Medical University, Beijing 101100, China.
Sun H; General Surgery, Luhe Hospital, Capital Medical University, Beijing 101100, China.
Qiu F; General Surgery, Luhe Hospital, Capital Medical University, Beijing 101100, China.
Liu J; General Surgery, Tongren Hospital, Capital Medical University, Beijing 101100, China.
Yang T; General Surgery, Luhe Hospital, Capital Medical University, Beijing 101100, China.
Han W; General Surgery, Luhe Hospital, Capital Medical University, Beijing 101100, China.
Pokaż więcej
Źródło:
BioMed research international [Biomed Res Int] 2021 Dec 29; Vol. 2021, pp. 1382061. Date of Electronic Publication: 2021 Dec 29 (Print Publication: 2021).
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Hepatocellular/*genetics
Cell Proliferation/*genetics
Down-Regulation/*genetics
Liver Neoplasms/*genetics
MicroRNAs/*genetics
Neoplasm Invasiveness/*genetics
Receptor, EphA2/*genetics
Apoptosis/genetics ; Carcinoma, Hepatocellular/pathology ; Cell Line, Tumor ; Cell Movement/genetics ; Erythropoietin/genetics ; Gene Expression Regulation, Neoplastic/genetics ; Hep G2 Cells ; Humans ; Liver Neoplasms/pathology ; Neoplasm Invasiveness/pathology ; Transfection/methods ; Up-Regulation/genetics
Czasopismo naukowe
Tytuł:
Catulin Based Reporter System to Track and Characterize the Population of Invasive Cancer Cells in the Head and Neck Squamous Cell Carcinoma.
Autorzy:
Karpińska K; Laboratory of the Molecular Biology of Cancer, Centre of New Technologies, University of Warsaw, 00-927 Warsaw, Poland.
Gielata M; Laboratory of the Molecular Biology of Cancer, Centre of New Technologies, University of Warsaw, 00-927 Warsaw, Poland.
Gwiazdowska A; Laboratory of the Molecular Biology of Cancer, Centre of New Technologies, University of Warsaw, 00-927 Warsaw, Poland.
Boryń Ł; Laboratory of Stem Cells, Tissue Development and Regeneration, Centre of New Technologies, University of Warsaw, 00-927 Warsaw, Poland.
Kobielak A; Laboratory of the Molecular Biology of Cancer, Centre of New Technologies, University of Warsaw, 00-927 Warsaw, Poland.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Dec 23; Vol. 23 (1). Date of Electronic Publication: 2021 Dec 23.
Typ publikacji:
Journal Article
MeSH Terms:
Genes, Reporter/*genetics
Head and Neck Neoplasms/*genetics
Neoplasm Invasiveness/*genetics
Squamous Cell Carcinoma of Head and Neck/*genetics
alpha Catenin/*genetics
Animals ; Cell Line, Tumor ; Cell Movement/genetics ; Epithelial-Mesenchymal Transition/genetics ; Gene Expression Regulation, Neoplastic/genetics ; Green Fluorescent Proteins/genetics ; Head and Neck Neoplasms/pathology ; Humans ; Mice ; Mice, Inbred NOD ; Mice, SCID ; Neoplasm Invasiveness/pathology ; Neural Cell Adhesion Molecule L1/genetics ; Squamous Cell Carcinoma of Head and Neck/pathology ; Up-Regulation/genetics
Czasopismo naukowe
Tytuł:
KIAA1217 Promotes Epithelial-Mesenchymal Transition and Hepatocellular Carcinoma Metastasis by Interacting with and Activating STAT3.
Autorzy:
Wang Y; National Engineering Laboratory for Druggable Gene and Protein Screening, Northeast Normal University, Changchun 130024, China.; NMPA Key Laboratory for Quality of Cell and Gene Therapy Medicinal Products, Northeast Normal University, Changchun 130024, China.
Li N; National Engineering Laboratory for Druggable Gene and Protein Screening, Northeast Normal University, Changchun 130024, China.
Zheng Y; National Engineering Laboratory for Druggable Gene and Protein Screening, Northeast Normal University, Changchun 130024, China.
Wang A; National Engineering Laboratory for Druggable Gene and Protein Screening, Northeast Normal University, Changchun 130024, China.
Yu C; National Engineering Laboratory for Druggable Gene and Protein Screening, Northeast Normal University, Changchun 130024, China.
Song Z; NMPA Key Laboratory for Quality of Cell and Gene Therapy Medicinal Products, Northeast Normal University, Changchun 130024, China.
Wang S; NMPA Key Laboratory for Quality of Cell and Gene Therapy Medicinal Products, Northeast Normal University, Changchun 130024, China.
Sun Y; National Engineering Laboratory for Druggable Gene and Protein Screening, Northeast Normal University, Changchun 130024, China.
Zheng L; NMPA Key Laboratory for Quality of Cell and Gene Therapy Medicinal Products, Northeast Normal University, Changchun 130024, China.
Wang G; NMPA Key Laboratory for Quality of Cell and Gene Therapy Medicinal Products, Northeast Normal University, Changchun 130024, China.
Liu L; NMPA Key Laboratory for Quality of Cell and Gene Therapy Medicinal Products, Northeast Normal University, Changchun 130024, China.
Yi J; NMPA Key Laboratory for Quality of Cell and Gene Therapy Medicinal Products, Northeast Normal University, Changchun 130024, China.
Huang Y; National Engineering Laboratory for Druggable Gene and Protein Screening, Northeast Normal University, Changchun 130024, China.
Zhang M; School of Molecular and Cellular Biology, University of Illinois Urbana Champaign, Urbana, IL 61801, USA.
Bao Y; National Engineering Laboratory for Druggable Gene and Protein Screening, Northeast Normal University, Changchun 130024, China.
Sun L; National Engineering Laboratory for Druggable Gene and Protein Screening, Northeast Normal University, Changchun 130024, China.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Dec 22; Vol. 23 (1). Date of Electronic Publication: 2021 Dec 22.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Hepatocellular/*genetics
Epithelial-Mesenchymal Transition/*genetics
Liver Neoplasms/*genetics
Neoplasm Invasiveness/*genetics
STAT3 Transcription Factor/*genetics
Animals ; Carcinoma, Hepatocellular/pathology ; Cell Line ; Cell Line, Tumor ; Cell Movement/genetics ; Female ; Gene Expression Regulation, Neoplastic/genetics ; HEK293 Cells ; Hep G2 Cells ; Humans ; Liver Neoplasms/pathology ; Lung Neoplasms/genetics ; Lung Neoplasms/pathology ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Neoplasm Invasiveness/pathology ; Prognosis ; Transcriptional Activation/genetics ; Up-Regulation/genetics ; Wnt Signaling Pathway/genetics ; beta Catenin/genetics
Czasopismo naukowe
Tytuł:
Identification of TRPV4 as a novel target in invasiveness of colorectal cancer.
Autorzy:
Zhang P; Longgang E.N.T. Hospital & Shenzhen Key Laboratory of E.N.T., Institute of E.N.T, No. 3004 Longgang Avenue, Shenzhen, Guangdong, China. .
Xu J; Longgang E.N.T. Hospital & Shenzhen Key Laboratory of E.N.T., Institute of E.N.T, No. 3004 Longgang Avenue, Shenzhen, Guangdong, China.
Zhang H; Longgang E.N.T. Hospital & Shenzhen Key Laboratory of E.N.T., Institute of E.N.T, No. 3004 Longgang Avenue, Shenzhen, Guangdong, China.
Liu XY; School of Medicine, Jiangnan University, Wuxi, Jiangsu, China. .; School of Medicine, Southern University of Science and Technology, 1088 Xueyuan Avenue, Shenzhen, Guangdong, China. .
Pokaż więcej
Źródło:
BMC cancer [BMC Cancer] 2021 Nov 23; Vol. 21 (1), pp. 1264. Date of Electronic Publication: 2021 Nov 23.
Typ publikacji:
Journal Article
MeSH Terms:
Epithelial-Mesenchymal Transition*
Neoplasm Invasiveness*
Colonic Neoplasms/*pathology
Rectal Neoplasms/*pathology
TRPV Cation Channels/*metabolism
Zinc Finger E-box-Binding Homeobox 1/*metabolism
Cell Line, Tumor ; Cell Movement ; Colonic Neoplasms/chemistry ; Colonic Neoplasms/metabolism ; Female ; HCT116 Cells ; Humans ; Immunohistochemistry ; Male ; Middle Aged ; Morpholines/pharmacology ; Neoplasm Metastasis ; Proto-Oncogene Proteins c-akt/metabolism ; Pyrroles/pharmacology ; RNA, Small Interfering ; Rectal Neoplasms/chemistry ; Rectal Neoplasms/metabolism ; TRPV Cation Channels/analysis ; TRPV Cation Channels/antagonists & inhibitors ; Transfection/methods ; Zinc Finger E-box-Binding Homeobox 1/analysis
Czasopismo naukowe
Tytuł:
The neuropeptide calcitonin gene-related peptide links perineural invasion with lymph node metastasis in oral squamous cell carcinoma.
Autorzy:
Zhang Y; Department of Oral Maxillofacial-Head Neck Oncology, Shanghai Ninth People's Hospital, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, China.; College of Stomatology, Shanghai Jiao Tong University, Shanghai, 200011, China.; National Center for Stomatology, National Clinical Research Center for Oral Diseases, Shanghai, 200011, China.; Shanghai Key Laboratory of Stomatology, Shanghai, 200011, China.
Chen M; Department of Oral Maxillofacial-Head Neck Oncology, Shanghai Ninth People's Hospital, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, China.; College of Stomatology, Shanghai Jiao Tong University, Shanghai, 200011, China.; National Center for Stomatology, National Clinical Research Center for Oral Diseases, Shanghai, 200011, China.; Shanghai Key Laboratory of Stomatology, Shanghai, 200011, China.
Liu Z; Department of Oral Maxillofacial-Head Neck Oncology, Shanghai Ninth People's Hospital, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, China.; College of Stomatology, Shanghai Jiao Tong University, Shanghai, 200011, China.; National Center for Stomatology, National Clinical Research Center for Oral Diseases, Shanghai, 200011, China.; Shanghai Key Laboratory of Stomatology, Shanghai, 200011, China.
Wang X; Department of Oral Maxillofacial-Head Neck Oncology, Shanghai Ninth People's Hospital, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, China. .; College of Stomatology, Shanghai Jiao Tong University, Shanghai, 200011, China. .; National Center for Stomatology, National Clinical Research Center for Oral Diseases, Shanghai, 200011, China. .; Shanghai Key Laboratory of Stomatology, Shanghai, 200011, China. .
Ji T; Department of Oral Maxillofacial-Head Neck Oncology, Shanghai Ninth People's Hospital, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, China. .; College of Stomatology, Shanghai Jiao Tong University, Shanghai, 200011, China. .; National Center for Stomatology, National Clinical Research Center for Oral Diseases, Shanghai, 200011, China. .; Shanghai Key Laboratory of Stomatology, Shanghai, 200011, China. .
Pokaż więcej
Źródło:
BMC cancer [BMC Cancer] 2021 Nov 20; Vol. 21 (1), pp. 1254. Date of Electronic Publication: 2021 Nov 20.
Typ publikacji:
Journal Article
MeSH Terms:
Lymphatic Metastasis*/pathology
Neoplasm Invasiveness*/pathology
Calcitonin Gene-Related Peptide/*blood
Mouth Neoplasms/*blood
Squamous Cell Carcinoma of Head and Neck/*blood
Area Under Curve ; Calcitonin Gene-Related Peptide/analysis ; Cell Line, Tumor ; Enzyme-Linked Immunosorbent Assay ; Female ; Humans ; Immunohistochemistry ; Male ; Middle Aged ; Mouth Neoplasms/chemistry ; Mouth Neoplasms/pathology ; Neoplasm Staging ; Retrospective Studies ; Squamous Cell Carcinoma of Head and Neck/chemistry ; Squamous Cell Carcinoma of Head and Neck/pathology ; Up-Regulation
Czasopismo naukowe
Tytuł:
Biological evaluation of antiproliferative and anti-invasive properties of an androstadiene derivative on human cervical cancer cell lines.
Autorzy:
Kulmány ÁE; Department of Pharmacodynamics and Biopharmacy, University of Szeged, Szeged, Hungary.
Frank É; Department of Organic Chemistry, University of Szeged, Szeged, Hungary.
Papp D; Department of Microbiology, University of Szeged, Szeged, Hungary.
Szekeres A; Department of Microbiology, University of Szeged, Szeged, Hungary.
Szebeni GJ; Laboratory of Functional Genomics, Biological Research Centre, Szeged, Hungary; Department of Physiology, Anatomy and Neuroscience, Faculty of Science and Informatics, University of Szeged, Szeged, Hungary.
Zupkó I; Department of Pharmacodynamics and Biopharmacy, University of Szeged, Szeged, Hungary. Electronic address: .
Pokaż więcej
Źródło:
The Journal of steroid biochemistry and molecular biology [J Steroid Biochem Mol Biol] 2021 Nov; Vol. 214, pp. 105990. Date of Electronic Publication: 2021 Aug 31.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Neoplasm Invasiveness*
Androstadienes/*chemistry
Uterine Cervical Neoplasms/*drug therapy
Androstadienes/pharmacology ; Animals ; Antineoplastic Agents/pharmacology ; Apoptosis ; Bisbenzimidazole ; Caspase 3/metabolism ; Cell Line, Tumor ; Cell Movement ; Cell Proliferation ; Cisplatin/pharmacology ; Female ; HeLa Cells ; Humans ; Inhibitory Concentration 50 ; Mice ; NIH 3T3 Cells ; Propidium ; Tetrazolium Salts/pharmacology ; Thiazoles/pharmacology ; Wound Healing
Czasopismo naukowe
Tytuł:
Nkx3-1 and Fech genes might be switch genes involved in pituitary non-functioning adenoma invasiveness.
Autorzy:
Khayer N; Skull Base Research Center, The Five Senses Health Institute, Iran University of Medical Sciences, Tehran, Iran.
Jalessi M; Skull Base Research Center, The Five Senses Health Institute, Iran University of Medical Sciences, Tehran, Iran. .; ENT and Head & Neck Research Center and Department, Hazrat Rasoul Hospital, Iran University of Medical Sciences, Tehran, Iran. .
Jahanbakhshi A; Skull Base Research Center, The Five Senses Health Institute, Iran University of Medical Sciences, Tehran, Iran.; Neurology Department, Hazrat Rasoul Hospital, Iran University of Medical Sciences, Tehran, Iran.
Tabib Khooei A; Neurology Department, Hazrat Rasoul Hospital, Iran University of Medical Sciences, Tehran, Iran.
Mirzaie M; Department of Applied Mathematics, Faculty of Mathematical Sciences, Tarbiat Modares University, Tehran, Iran. .
Pokaż więcej
Źródło:
Scientific reports [Sci Rep] 2021 Oct 22; Vol. 11 (1), pp. 20943. Date of Electronic Publication: 2021 Oct 22.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Adenoma/*genetics
Ferrochelatase/*genetics
Genes, Switch/*genetics
Homeodomain Proteins/*genetics
Neoplasm Invasiveness/*genetics
Pituitary Neoplasms/*genetics
Transcription Factors/*genetics
Adenoma/pathology ; Biomarkers, Tumor/genetics ; Gene Expression Regulation, Neoplastic/genetics ; Gene Regulatory Networks/genetics ; Humans ; Neoplasm Invasiveness/pathology ; Pituitary Neoplasms/pathology ; RNA, Messenger/genetics ; Sella Turcica/pathology
Czasopismo naukowe
Tytuł:
Predicting microvascular invasion in hepatocellular carcinoma: a deep learning model validated across hospitals.
Autorzy:
Liu SC; AI Innovation Center, China Medical University Hospital, Taichung, Taiwan.
Lai J; AI Innovation Center, China Medical University Hospital, Taichung, Taiwan.
Huang JY; AI Innovation Center, China Medical University Hospital, Taichung, Taiwan.
Cho CF; AI Innovation Center, China Medical University Hospital, Taichung, Taiwan.
Lee PH; Department of Medical Imaging, China Medical University Hospital, Taichung, Taiwan.
Lu MH; AI Innovation Center, China Medical University Hospital, Taichung, Taiwan.
Yeh CC; Department of Surgery, Organ Transplantation Center, China Medical University Hospital, Taichung, Taiwan.; Department of Medicine, School of Medicine, China Medical University, Taichung, Taiwan.; Department of Surgery, Asia University Hospital, Taichung, Taiwan, 41354.
Yu J; AI Innovation Center, China Medical University Hospital, Taichung, Taiwan. .
Lin WC; AI Innovation Center, China Medical University Hospital, Taichung, Taiwan. .; Department of Medical Imaging, China Medical University Hospital, Taichung, Taiwan. .; Department of Biomedical Imaging and Radiological Science, School of Medicine, China Medical University, Taichung, Taiwan. .
Pokaż więcej
Źródło:
Cancer imaging : the official publication of the International Cancer Imaging Society [Cancer Imaging] 2021 Oct 09; Vol. 21 (1), pp. 56. Date of Electronic Publication: 2021 Oct 09.
Typ publikacji:
Journal Article
MeSH Terms:
Deep Learning*
Neoplasm Invasiveness*
Carcinoma, Hepatocellular/*diagnostic imaging
Liver Neoplasms/*diagnostic imaging
Aged ; Carcinoma, Hepatocellular/blood supply ; Female ; Hospitals ; Humans ; Liver Neoplasms/blood supply ; Male ; Middle Aged ; Neural Networks, Computer ; Retrospective Studies
Czasopismo naukowe
Tytuł:
Transcription factor POU4F2 promotes colorectal cancer cell migration and invasion through hedgehog-mediated epithelial-mesenchymal transition.
Autorzy:
Guo K; The First School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, China.
Wang P; The First School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, China.
Zhang L; The First School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, China.
Zhou Y; The Second School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, China.
Dai X; The First School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, China.
Yan Y; The First School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, China.
Chen Y; The First School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, China.
Wasan HS; Department of Cancer Medicine, Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, UK.
Yu J; School of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou, China.
Ruan S; Department of Medical Oncology, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Traditional Chinese Medicine), Hangzhou, China.
Sun L; Department of Medical Oncology, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Traditional Chinese Medicine), Hangzhou, China.
Pokaż więcej
Źródło:
Cancer science [Cancer Sci] 2021 Oct; Vol. 112 (10), pp. 4176-4186. Date of Electronic Publication: 2021 Aug 10.
Typ publikacji:
Journal Article
MeSH Terms:
Cell Movement*
Neoplasm Invasiveness*
Colorectal Neoplasms/*metabolism
Epithelial-Mesenchymal Transition/*physiology
Hedgehog Proteins/*metabolism
Transcription Factor Brn-3B/*physiology
Animals ; Cell Line, Tumor ; Colon/metabolism ; Colon/pathology ; Colorectal Neoplasms/pathology ; Cyclohexylamines/pharmacology ; Down-Regulation ; Gene Silencing ; Humans ; Lung Neoplasms/secondary ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Molecular Targeted Therapy ; Patched-1 Receptor/metabolism ; RNA, Messenger/metabolism ; RNA, Small Interfering/metabolism ; Signal Transduction ; Smoothened Receptor/agonists ; Smoothened Receptor/metabolism ; Thiophenes/pharmacology ; Transcription Factor Brn-3B/antagonists & inhibitors ; Transcription Factor Brn-3B/genetics ; Transcription Factor Brn-3B/metabolism ; Up-Regulation ; Zinc Fingers
Czasopismo naukowe
Tytuł:
Store-operated Ca signaling driving tumor invasion-metastasis cascade and its translational potential.
Autorzy:
Wei J; Department of Otolaryngology & Head and Neck, The People's Hospital of Guangxi Zhuang Autonomous Region, Guangxi Academy of Medical Sciences, 6 Taoyuan Road, Nanning, 530021, China.
Deng Y; Department of Medical Oncology, Guangxi Medical University Cancer Hospital, 71 Hedi Road, Nanning, 530021, China.
Ye J; Department of Medical Oncology, Guangxi Medical University Cancer Hospital, 71 Hedi Road, Nanning, 530021, China.
Luo Y; Department of Medical Oncology, Guangxi Medical University Cancer Hospital, 71 Hedi Road, Nanning, 530021, China.
Weng J; Department of Otolaryngology & Head and Neck, The People's Hospital of Guangxi Zhuang Autonomous Region, Guangxi Academy of Medical Sciences, 6 Taoyuan Road, Nanning, 530021, China.
He Q; Center of Precision Medicine and Healthcare, Tsinghua-Berkeley Shenzhen Institute, Shenzhen, 518055, China.
Liu F; Research Center of Medical Sciences, The People's Hospital of Guangxi Zhuang Autonomous Region, Guangxi Academy of Medical Sciences, Nanning, 530021, China.
Li M; Department of Otolaryngology & Head and Neck, The People's Hospital of Guangxi Zhuang Autonomous Region, Guangxi Academy of Medical Sciences, 6 Taoyuan Road, Nanning, 530021, China.
Liang R; Department of Medical Oncology, Guangxi Medical University Cancer Hospital, 71 Hedi Road, Nanning, 530021, China.
Lin Y; Department of Medical Oncology, Guangxi Medical University Cancer Hospital, 71 Hedi Road, Nanning, 530021, China.
Li Y; Department of Medical Oncology, Guangxi Medical University Cancer Hospital, 71 Hedi Road, Nanning, 530021, China.
Zhang J; Department of Medical Oncology, Guangxi Medical University Cancer Hospital, 71 Hedi Road, Nanning, 530021, China. Electronic address: .
Yang J; Department of Hepatobiliary, Pancreas and Spleen Surgery, The People's Hospital of Guangxi Zhuang Autonomous Region, Guangxi Academy of Medical Sciences, Nanning, 530021, China. Electronic address: .
Qu S; Department of Otolaryngology & Head and Neck, The People's Hospital of Guangxi Zhuang Autonomous Region, Guangxi Academy of Medical Sciences, 6 Taoyuan Road, Nanning, 530021, China. Electronic address: .
Pokaż więcej
Źródło:
Cancer letters [Cancer Lett] 2021 Sep 28; Vol. 516, pp. 64-72. Date of Electronic Publication: 2021 Jun 02.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Calcium/*metabolism
Calcium Signaling/*genetics
Neoplasm Invasiveness/*genetics
Neoplasm Metastasis/*genetics
Oncogenes/*genetics
Animals ; Humans ; Neoplasm Invasiveness/pathology ; Neoplasm Metastasis/pathology
Czasopismo naukowe

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies

Prześlij opinię

Twoje opinie są dla nas bardzo ważne i mogą być niezwykle pomocne w pokazaniu nam, gdzie możemy dokonać ulepszeń. Bylibyśmy bardzo wdzięczni za poświęcenie kilku chwil na wypełnienie krótkiego formularza.

Formularz