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Wyszukujesz frazę ""Neoplasm Metastasis"" wg kryterium: Temat


Tytuł :
CYFRA21-1/TG ratio as an accurate risk factor to predict eye metastasis in nasopharyngeal carcinoma: A STROBE-compliant article.
Autorzy :
Peng SJ; Department of Ophthalmology, The First Affiliated Hospital of Nanchang University, Jiangxi Province Clinical Ophthalmology Institute, Nanchang, Jiangxi, China.
Wang CF
Yu YJ
Yu CY
Chen SY
Wu SN
Tan SW
Peng JX
Li B
Shao Y
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Źródło :
Medicine [Medicine (Baltimore)] 2020 Nov 13; Vol. 99 (46), pp. e22773.
Typ publikacji :
Journal Article
MeSH Terms :
Antigens, Neoplasm/*analysis
Eye Neoplasms/*etiology
Keratin-19/*analysis
Nasopharyngeal Neoplasms/*genetics
Neoplasm Metastasis/*diagnosis
Thyroglobulin/*analysis
Adult ; Antigens, Neoplasm/blood ; Biomarkers, Tumor/analysis ; China/epidemiology ; Eye Neoplasms/epidemiology ; Eye Neoplasms/genetics ; Female ; Humans ; Keratin-19/blood ; Logistic Models ; Male ; Middle Aged ; Nasopharyngeal Neoplasms/epidemiology ; Neoplasm Metastasis/diagnostic imaging ; Neoplasm Metastasis/physiopathology ; Risk Factors ; Sensitivity and Specificity ; Thyroglobulin/blood
Czasopismo naukowe
Tytuł :
PtdIns(3,4,5)P 3 -dependent Rac exchanger 1 (P-Rex1) promotes mammary tumor initiation and metastasis.
Autorzy :
Srijakotre N; Cancer Program, Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC 3800, Australia.
Liu HJ; Cancer Program, Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC 3800, Australia.
Nobis M; Garvan Institute of Medical Research, Faculty of Medicine, St Vincent's Clinical School, University of New South Wales (UNSW) Sydney, Darlinghurst, NSW 2010, Australia.
Man J; Cancer Program, Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC 3800, Australia.
Yip HYK; Cancer Program, Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC 3800, Australia.
Papa A; Cancer Program, Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC 3800, Australia.
Abud HE; Development and Stem Cells Program, Monash Biomedicine Discovery Institute and Department of Anatomy and Developmental Biology, Monash University, Clayton, VIC 3800, Australia.
Anderson KI; Tumour Cell Migration, Cancer Research UK Beatson Institute, G611BD Glasgow, United Kingdom.; Crick Advanced Light Microscopy, Francis Crick Institute, NW11AT London, United Kingdom.
Welch HCE; Signalling Programme, Babraham Institute, CB22 3AT Cambridge, United Kingdom.
Tiganis T; Cancer Program, Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC 3800, Australia.; Peter MacCallum Cancer Centre, Melbourne, VIC 3000, Australia.
Timpson P; Garvan Institute of Medical Research, Faculty of Medicine, St Vincent's Clinical School, University of New South Wales (UNSW) Sydney, Darlinghurst, NSW 2010, Australia.
McLean CA; Department of Anatomical Pathology, Alfred Hospital, Prahran, VIC 3181, Australia.
Ooms LM; Cancer Program, Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC 3800, Australia.
Mitchell CA; Cancer Program, Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC 3800, Australia; .
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Nov 10; Vol. 117 (45), pp. 28056-28067. Date of Electronic Publication: 2020 Oct 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Guanine Nucleotide Exchange Factors*/genetics
Guanine Nucleotide Exchange Factors*/metabolism
Mammary Neoplasms, Experimental*/metabolism
Mammary Neoplasms, Experimental*/pathology
Neoplasm Metastasis*/genetics
Neoplasm Metastasis*/pathology
Animals ; Cell Polarity/genetics ; Female ; Male ; Mice ; Mice, Transgenic ; Neoplasm Invasiveness/genetics ; Neoplasm Invasiveness/pathology
Czasopismo naukowe
Tytuł :
Cancer progression and the invisible phase of metastatic colonization.
Autorzy :
Klein CA; Experimental Medicine and Therapy Research, University of Regensburg, Regensburg, Germany. .; Division of Personalized Tumor Therapy, Fraunhofer Institute for Toxicology and Experimental Medicine, Regensburg, Germany. .
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Źródło :
Nature reviews. Cancer [Nat Rev Cancer] 2020 Nov; Vol. 20 (11), pp. 681-694. Date of Electronic Publication: 2020 Oct 06.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Neoplasms, Second Primary*/physiopathology
Neoplasms, Second Primary*/prevention & control
Neoplasm Metastasis/*physiopathology
Disease Progression ; Humans ; Neoplasm Metastasis/genetics ; Neoplasm Metastasis/therapy ; Neoplasms/physiopathology ; Neoplastic Processes
Czasopismo naukowe
Tytuł :
β2-AR activation promotes cleavage and nuclear translocation of Her2 and metastatic potential of cancer cells.
Autorzy :
Liu D; Cancer Institute, Xuzhou Medical University, Xuzhou, China.; Center of Clinical Oncology, Affiliated Hospital of Xuzhou Medical University, Xuzhou Medical University, Xuzhou, China.
Zha L; Cancer Institute, Xuzhou Medical University, Xuzhou, China.; Center of Clinical Oncology, Affiliated Hospital of Xuzhou Medical University, Xuzhou Medical University, Xuzhou, China.
Liu Y; Cancer Institute, Xuzhou Medical University, Xuzhou, China.; Center of Clinical Oncology, Affiliated Hospital of Xuzhou Medical University, Xuzhou Medical University, Xuzhou, China.
Zhao X; Cancer Institute, Xuzhou Medical University, Xuzhou, China.; Center of Clinical Oncology, Affiliated Hospital of Xuzhou Medical University, Xuzhou Medical University, Xuzhou, China.
Xu X; Cancer Institute, Xuzhou Medical University, Xuzhou, China.; Center of Clinical Oncology, Affiliated Hospital of Xuzhou Medical University, Xuzhou Medical University, Xuzhou, China.
Liu S; Cancer Institute, Xuzhou Medical University, Xuzhou, China.; Center of Clinical Oncology, Affiliated Hospital of Xuzhou Medical University, Xuzhou Medical University, Xuzhou, China.
Ma W; Cancer Institute, Xuzhou Medical University, Xuzhou, China.; Center of Clinical Oncology, Affiliated Hospital of Xuzhou Medical University, Xuzhou Medical University, Xuzhou, China.
Zheng J; Center of Clinical Oncology, Affiliated Hospital of Xuzhou Medical University, Xuzhou Medical University, Xuzhou, China.
Shi M; Cancer Institute, Xuzhou Medical University, Xuzhou, China.; Center of Clinical Oncology, Affiliated Hospital of Xuzhou Medical University, Xuzhou Medical University, Xuzhou, China.
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Źródło :
Cancer science [Cancer Sci] 2020 Dec; Vol. 111 (12), pp. 4417-4428. Date of Electronic Publication: 2020 Oct 27.
Typ publikacji :
Journal Article
MeSH Terms :
Neoplasm Metastasis*
Catecholamines/*pharmacology
Cell Nucleus/*metabolism
Receptor, ErbB-2/*metabolism
Receptors, Adrenergic, beta-2/*metabolism
ADAM10 Protein/metabolism ; Adrenergic beta-2 Receptor Agonists/pharmacology ; Amyloid Precursor Protein Secretases/metabolism ; Animals ; Breast Neoplasms/metabolism ; Cell Line, Tumor ; Cyclooxygenase 2/genetics ; Female ; Humans ; Isoproterenol/pharmacology ; Lung Neoplasms/secondary ; MCF-7 Cells ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; MicroRNAs/metabolism ; Neoplasm Invasiveness ; Proteolysis ; Signal Transduction ; Sirtuin 1/metabolism ; Transcriptional Activation
Czasopismo naukowe
Tytuł :
Divergent organ-specific isogenic metastatic cell lines identified using multi-omics exhibit differential drug sensitivity.
Autorzy :
Winnard PT Jr; Division of Cancer Imaging Research, The Russell H Morgan Department of Radiology and Radiological Sciences, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.
Vesuna F; Division of Cancer Imaging Research, The Russell H Morgan Department of Radiology and Radiological Sciences, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.
Muthukumar S; Division of Cancer Imaging Research, The Russell H Morgan Department of Radiology and Radiological Sciences, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.
Raman V; Division of Cancer Imaging Research, The Russell H Morgan Department of Radiology and Radiological Sciences, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.; Department of Oncology, The Johns Hopkins University, School of Medicine, Baltimore, Maryland, United States of America.; Department of Pathology, University Medical Center Utrecht, Utrecht, The Netherlands.
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Źródło :
PloS one [PLoS One] 2020 Nov 16; Vol. 15 (11), pp. e0242384. Date of Electronic Publication: 2020 Nov 16 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Breast Neoplasms/*pathology
Cell Line, Tumor/*pathology
Neoplasm Metastasis/*physiopathology
Biomarkers, Pharmacological/metabolism ; Female ; Humans ; Neoplasm Metastasis/prevention & control ; Pharmaceutical Preparations/metabolism ; Proteomics/methods
Czasopismo naukowe
Tytuł :
Age-induced accumulation of methylmalonic acid promotes tumour progression.
Autorzy :
Gomes AP; Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA. .; Department of Pharmacology, Weill Cornell Medicine, New York, NY, USA. .; Department of Molecular Oncology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida, USA. .
Ilter D; Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.; Department of Pharmacology, Weill Cornell Medicine, New York, NY, USA.; Department of Molecular Oncology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida, USA.
Low V; Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.; The Biochemistry, Structural, Developmental, Cell and Molecular Biology Allied PhD Program, Weill Cornell Medicine, New York, NY, USA.
Endress JE; Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.; The Biochemistry, Structural, Developmental, Cell and Molecular Biology Allied PhD Program, Weill Cornell Medicine, New York, NY, USA.
Fernández-García J; Laboratory of Cellular Metabolism and Metabolic Regulation, VIB-KU Leuven Center for Cancer Biology, VIB, Leuven, Belgium.; Laboratory of Cellular Metabolism and Metabolic Regulation, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Leuven, Belgium.
Rosenzweig A; Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.; Department of Pharmacology, Weill Cornell Medicine, New York, NY, USA.
Schild T; Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.; The Biochemistry, Structural, Developmental, Cell and Molecular Biology Allied PhD Program, Weill Cornell Medicine, New York, NY, USA.
Broekaert D; Laboratory of Cellular Metabolism and Metabolic Regulation, VIB-KU Leuven Center for Cancer Biology, VIB, Leuven, Belgium.; Laboratory of Cellular Metabolism and Metabolic Regulation, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Leuven, Belgium.
Ahmed A; Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.; Department of Biochemistry, Weill Cornell Medicine, New York, NY, USA.
Planque M; Laboratory of Cellular Metabolism and Metabolic Regulation, VIB-KU Leuven Center for Cancer Biology, VIB, Leuven, Belgium.; Laboratory of Cellular Metabolism and Metabolic Regulation, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Leuven, Belgium.
Elia I; Laboratory of Cellular Metabolism and Metabolic Regulation, VIB-KU Leuven Center for Cancer Biology, VIB, Leuven, Belgium.; Laboratory of Cellular Metabolism and Metabolic Regulation, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Leuven, Belgium.
Han J; Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.; Department of Pharmacology, Weill Cornell Medicine, New York, NY, USA.
Kinzig C; Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.; Weill Cornell Medicine/Rockefeller University/Sloan Kettering Tri-Institutional MD-PhD Program, New York, NY, USA.
Mullarky E; Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.; Department of Medicine, Weill Cornell Medicine, New York, NY, USA.
Mutvei AP; Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.; Department of Pharmacology, Weill Cornell Medicine, New York, NY, USA.
Asara J; Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA.
de Cabo R; Laboratory of Experimental Gerontology, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA.
Cantley LC; Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.; Department of Medicine, Weill Cornell Medicine, New York, NY, USA.
Dephoure N; Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.; Department of Biochemistry, Weill Cornell Medicine, New York, NY, USA.
Fendt SM; Laboratory of Cellular Metabolism and Metabolic Regulation, VIB-KU Leuven Center for Cancer Biology, VIB, Leuven, Belgium.; Laboratory of Cellular Metabolism and Metabolic Regulation, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Leuven, Belgium.
Blenis J; Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA. .; Department of Pharmacology, Weill Cornell Medicine, New York, NY, USA. .; Department of Biochemistry, Weill Cornell Medicine, New York, NY, USA. .
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Źródło :
Nature [Nature] 2020 Sep; Vol. 585 (7824), pp. 283-287. Date of Electronic Publication: 2020 Aug 19.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Disease Progression*
Neoplasm Invasiveness*/genetics
Neoplasm Invasiveness*/pathology
Neoplasm Metastasis*/genetics
Neoplasm Metastasis*/pathology
Aging/*metabolism
Methylmalonic Acid/*metabolism
Neoplasms/*pathology
Adult ; Aged ; Aging/blood ; Aging/genetics ; Animals ; Cell Line, Tumor ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; Male ; Methylmalonic Acid/blood ; Mice ; Middle Aged ; Neoplasms/blood ; Neoplasms/genetics ; SOXC Transcription Factors/metabolism ; Signal Transduction ; Transcriptome/genetics ; Transforming Growth Factor beta/metabolism
Czasopismo naukowe
Tytuł :
Association of Sociodemographic Factors With Immunotherapy Receipt for Metastatic Melanoma in the US.
Autorzy :
Moyers JT; Division of Hematology and Oncology, Department of Internal Medicine, Loma Linda University, Loma Linda, California.
Patel A; Department of Internal Medicine, Loma Linda University, Loma Linda, California.
Shih W; School of Public Heath, Loma Linda University, Loma Linda, California.
Nagaraj G; Division of Hematology and Oncology, Department of Internal Medicine, Loma Linda University, Loma Linda, California.
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Źródło :
JAMA network open [JAMA Netw Open] 2020 Sep 01; Vol. 3 (9), pp. e2015656. Date of Electronic Publication: 2020 Sep 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Immunotherapy*/methods
Immunotherapy*/statistics & numerical data
Melanoma*/epidemiology
Melanoma*/pathology
Melanoma*/therapy
Neoplasm Metastasis*/pathology
Neoplasm Metastasis*/prevention & control
Immune Checkpoint Inhibitors/*therapeutic use
Demography ; Female ; Healthcare Disparities/statistics & numerical data ; Humans ; Male ; Medicaid/statistics & numerical data ; Middle Aged ; Neoplasm Staging ; Outcome Assessment, Health Care ; Socioeconomic Factors ; Survival Analysis ; United States/epidemiology
Czasopismo naukowe
Tytuł :
Surgical treatment of a rare case of hepatocellular carcinoma with right atrial metastasis: A case report.
Autorzy :
Qiu W; Department of Hepatobiliary and Pancreatic Surgery, The First Hospital of Jilin University, Changchun, Jilin, China.
Wang C
Zhang R
Wei F
Shi X
Sun X
Ma D
Lv G
Wang G
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Źródło :
Medicine [Medicine (Baltimore)] 2020 Aug 07; Vol. 99 (32), pp. e21630.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Carcinoma, Hepatocellular/*surgery
Heart Atria/*abnormalities
Neoplasm Metastasis/*diagnosis
Carcinoma, Hepatocellular/complications ; Heart Atria/surgery ; Hepatectomy/methods ; Humans ; Liver Neoplasms/diagnosis ; Liver Neoplasms/diagnostic imaging ; Liver Neoplasms/surgery ; Male ; Middle Aged ; Neoplasm Metastasis/physiopathology ; Neoplasm Metastasis/therapy ; Tomography, X-Ray Computed/methods ; Treatment Outcome ; Vena Cava, Inferior/surgery
Czasopismo naukowe
Tytuł :
68Ga-PSMA-PET/CT-based radiosurgery and stereotactic body radiotherapy for oligometastatic prostate cancer.
Autorzy :
Kalinauskaite G; Charité -Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Radiation Oncology and Radiotherapy, Berlin, Germany.; Charité CyberKnife Center, Departments of Radiation Oncology and Neurosurgery, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Senger C; Charité -Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Radiation Oncology and Radiotherapy, Berlin, Germany.; Charité CyberKnife Center, Departments of Radiation Oncology and Neurosurgery, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Kluge A; Charité -Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Radiation Oncology and Radiotherapy, Berlin, Germany.; Charité CyberKnife Center, Departments of Radiation Oncology and Neurosurgery, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Furth C; Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Nuclear Medicine, Berlin, Germany.
Kufeld M; Charité CyberKnife Center, Departments of Radiation Oncology and Neurosurgery, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Tinhofer I; Charité -Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Radiation Oncology and Radiotherapy, Berlin, Germany.; The Translational Radiooncology and Radiobiology Research Laboratory, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Budach V; Charité -Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Radiation Oncology and Radiotherapy, Berlin, Germany.; Charité CyberKnife Center, Departments of Radiation Oncology and Neurosurgery, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Beck M; Charité -Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Radiation Oncology and Radiotherapy, Berlin, Germany.; Charité CyberKnife Center, Departments of Radiation Oncology and Neurosurgery, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Hochreiter A; Charité -Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Radiation Oncology and Radiotherapy, Berlin, Germany.
Grün A; Charité -Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Radiation Oncology and Radiotherapy, Berlin, Germany.; Charité CyberKnife Center, Departments of Radiation Oncology and Neurosurgery, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Stromberger C; Charité -Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Radiation Oncology and Radiotherapy, Berlin, Germany.; Charité CyberKnife Center, Departments of Radiation Oncology and Neurosurgery, Charité - Universitätsmedizin Berlin, Berlin, Germany.
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Źródło :
PloS one [PLoS One] 2020 Oct 21; Vol. 15 (10), pp. e0240892. Date of Electronic Publication: 2020 Oct 21 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Membrane Glycoproteins/*administration & dosage
Neoplasm Metastasis/*radiotherapy
Organometallic Compounds/*administration & dosage
Prostatic Neoplasms/*radiotherapy
Radiopharmaceuticals/*administration & dosage
Aged ; Dose Fractionation, Radiation ; Humans ; Male ; Middle Aged ; Neoplasm Metastasis/diagnostic imaging ; Positron Emission Tomography Computed Tomography ; Prostatic Neoplasms/diagnostic imaging ; Retrospective Studies ; Robotic Surgical Procedures ; Survival Analysis ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Hypoxia-induced NAD interventions promote tumor survival and metastasis by regulating mitochondrial dynamics.
Autorzy :
Yan X; Key Laboratory of Pathobiology, Ministry of Education, Department of Pathophysiology, College of Basic Medical Sciences, Jilin University, Changchun, China.
Qu X; Department of Hepatobiliary & Pancreatic Surgery, The Second Hospital of Jilin University, Jilin University, Changchun, Jilin 130021, China.
Tian R; Key Laboratory of Pathobiology, Ministry of Education, Department of Pathophysiology, College of Basic Medical Sciences, Jilin University, Changchun, China.
Xu L; Key Laboratory of Pathobiology, Ministry of Education, Department of Pathophysiology, College of Basic Medical Sciences, Jilin University, Changchun, China.
Jin X; Key Laboratory of Pathobiology, Ministry of Education, Department of Pathophysiology, College of Basic Medical Sciences, Jilin University, Changchun, China.
Yu S; Key Laboratory of Pathobiology, Ministry of Education, Department of Pathophysiology, College of Basic Medical Sciences, Jilin University, Changchun, China.
Zhao Y; Key Laboratory of Pathobiology, Ministry of Education, Department of Pathophysiology, College of Basic Medical Sciences, Jilin University, Changchun, China.
Ma J; Key Laboratory of Pathobiology, Ministry of Education, Department of Pathophysiology, College of Basic Medical Sciences, Jilin University, Changchun, China.
Liu Y; Key Laboratory of Pathobiology, Ministry of Education, Department of Pathophysiology, College of Basic Medical Sciences, Jilin University, Changchun, China.
Sun L; Key Laboratory of Pathobiology, Ministry of Education, Department of Pathophysiology, College of Basic Medical Sciences, Jilin University, Changchun, China. Electronic address: .
Su J; Key Laboratory of Pathobiology, Ministry of Education, Department of Pathophysiology, College of Basic Medical Sciences, Jilin University, Changchun, China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2020 Oct 15; Vol. 259, pp. 118171. Date of Electronic Publication: 2020 Jul 30.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Mitochondrial Dynamics*
Neoplasm Metastasis*
Hypoxia/*metabolism
Mitochondria/*metabolism
NAD/*metabolism
Neoplasms/*metabolism
Animals ; Drug Resistance, Neoplasm ; Humans ; Tumor Microenvironment
Czasopismo naukowe
Tytuł :
Tumoural activation of TLR3-SLIT2 axis in endothelium drives metastasis.
Autorzy :
Tavora B; Laboratory of Systems Cancer Biology, The Rockefeller University, New York, NY, USA.
Mederer T; Laboratory of Systems Cancer Biology, The Rockefeller University, New York, NY, USA.
Wessel KJ; Laboratory of Systems Cancer Biology, The Rockefeller University, New York, NY, USA.
Ruffing S; Laboratory of Systems Cancer Biology, The Rockefeller University, New York, NY, USA.
Sadjadi M; Laboratory of Systems Cancer Biology, The Rockefeller University, New York, NY, USA.
Missmahl M; Laboratory of Systems Cancer Biology, The Rockefeller University, New York, NY, USA.
Ostendorf BN; Laboratory of Systems Cancer Biology, The Rockefeller University, New York, NY, USA.
Liu X; Laboratory of Systems Cancer Biology, The Rockefeller University, New York, NY, USA.
Kim JY; Laboratory of Systems Cancer Biology, The Rockefeller University, New York, NY, USA.
Olsen O; Laboratory of Brain Development and Repair, The Rockefeller University, New York, NY, USA.
Welm AL; Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA.
Goodarzi H; Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA, USA.
Tavazoie SF; Laboratory of Systems Cancer Biology, The Rockefeller University, New York, NY, USA. .
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Źródło :
Nature [Nature] 2020 Oct; Vol. 586 (7828), pp. 299-304. Date of Electronic Publication: 2020 Sep 30.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Neoplasm Metastasis*/genetics
Breast Neoplasms/*metabolism
Breast Neoplasms/*pathology
Endothelium/*metabolism
Intercellular Signaling Peptides and Proteins/*metabolism
Lung Neoplasms/*metabolism
Lung Neoplasms/*pathology
Nerve Tissue Proteins/*metabolism
Toll-Like Receptor 3/*metabolism
Animals ; Chemotaxis ; Disease Models, Animal ; Disease Progression ; Endothelial Cells/metabolism ; Female ; Humans ; Intercellular Signaling Peptides and Proteins/genetics ; Male ; Mice ; Nerve Tissue Proteins/genetics ; RNA, Double-Stranded ; Receptors, Immunologic/genetics ; Receptors, Immunologic/metabolism ; Signal Transduction ; Toll-Like Receptor 3/deficiency ; Toll-Like Receptor 3/genetics ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł :
Lymph protects metastasizing melanoma cells from ferroptosis.
Autorzy :
Ubellacker JM; Children's Research Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Tasdogan A; Children's Research Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Ramesh V; Children's Research Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Shen B; Children's Research Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Mitchell EC; Children's Research Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Martin-Sandoval MS; Children's Research Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Gu Z; Children's Research Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA.
McCormick ML; Free Radical and Radiation Biology Program, Department of Radiation Oncology, Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA, USA.
Durham AB; Department of Dermatology, University of Michigan, Ann Arbor, MI, USA.
Spitz DR; Free Radical and Radiation Biology Program, Department of Radiation Oncology, Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA, USA.
Zhao Z; Children's Research Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Mathews TP; Children's Research Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA.; Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Morrison SJ; Children's Research Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA. .; Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA. .; Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA. .
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Źródło :
Nature [Nature] 2020 Sep; Vol. 585 (7823), pp. 113-118. Date of Electronic Publication: 2020 Aug 19.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Ferroptosis*/drug effects
Lymph/*metabolism
Melanoma/*pathology
Neoplasm Metastasis/*pathology
Animals ; Cell Survival ; Coenzyme A Ligases/metabolism ; Female ; Glutathione/metabolism ; Humans ; Iron/metabolism ; Male ; Melanoma/blood ; Melanoma/metabolism ; Mice ; Neoplasm Metastasis/drug therapy ; Oleic Acid/metabolism ; Oxidative Stress/drug effects ; Phospholipid Hydroperoxide Glutathione Peroxidase/metabolism ; Principal Component Analysis
Czasopismo naukowe
Tytuł :
Long-term in vivo imaging reveals tumor-specific dissemination and captures host tumor interaction in zebrafish xenografts.
Autorzy :
Asokan N; Center for Regenerative Therapies Dresden (CRTD), Technische Universität Dresden, Fetscherstraße 105, 01307, Dresden, Germany.; Division of Hematology, Oncology and Stem Cell Transplantation, Medical Clinic I, Department of Medicine I, University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstraße 74, 01307, Dresden, Germany.
Daetwyler S; Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG), Dresden, Germany.
Bernas SN; Center for Regenerative Therapies Dresden (CRTD), Technische Universität Dresden, Fetscherstraße 105, 01307, Dresden, Germany.; German Center for Neurodegenerative Diseases (DZNE), Dresden, Germany.
Schmied C; German Center for Neurodegenerative Diseases (DZNE), Dresden, Germany.
Vogler S; German Center for Neurodegenerative Diseases (DZNE), Dresden, Germany.
Lambert K; Center for Regenerative Therapies Dresden (CRTD), Technische Universität Dresden, Fetscherstraße 105, 01307, Dresden, Germany.; Division of Hematology, Oncology and Stem Cell Transplantation, Medical Clinic I, Department of Medicine I, University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstraße 74, 01307, Dresden, Germany.
Wobus M; Division of Hematology, Oncology and Stem Cell Transplantation, Medical Clinic I, Department of Medicine I, University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstraße 74, 01307, Dresden, Germany.
Wermke M; Division of Hematology, Oncology and Stem Cell Transplantation, Medical Clinic I, Department of Medicine I, University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstraße 74, 01307, Dresden, Germany.
Kempermann G; Center for Regenerative Therapies Dresden (CRTD), Technische Universität Dresden, Fetscherstraße 105, 01307, Dresden, Germany.; German Center for Neurodegenerative Diseases (DZNE), Dresden, Germany.
Huisken J; Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG), Dresden, Germany.; Morgridge Institute for Research, Madison, USA.
Brand M; Center for Regenerative Therapies Dresden (CRTD), Technische Universität Dresden, Fetscherstraße 105, 01307, Dresden, Germany. .
Bornhäuser M; Center for Regenerative Therapies Dresden (CRTD), Technische Universität Dresden, Fetscherstraße 105, 01307, Dresden, Germany. .; Division of Hematology, Oncology and Stem Cell Transplantation, Medical Clinic I, Department of Medicine I, University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstraße 74, 01307, Dresden, Germany. .; National Center for Tumor Diseases (NCT), Dresden, Germany. .; German Consortium for Translational Cancer Research (DKTK), DKFZ, Heidelberg, Germany. .
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Źródło :
Scientific reports [Sci Rep] 2020 Aug 06; Vol. 10 (1), pp. 13254. Date of Electronic Publication: 2020 Aug 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine/*analogs & derivatives
Breast Neoplasms/*diagnostic imaging
Leukemia/*diagnostic imaging
Neoplasm Metastasis/*diagnostic imaging
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine/administration & dosage ; 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine/therapeutic use ; Animals ; Breast Neoplasms/drug therapy ; Cell Line, Tumor ; Cell Tracking ; Female ; Leukemia/drug therapy ; Microscopy ; Neoplasm Invasiveness ; Neoplasm Metastasis/drug therapy ; Neoplasm Transplantation ; Time-Lapse Imaging ; Zebrafish
Czasopismo naukowe
Tytuł :
Soluble Vegfr3 gene therapy suppresses multi-organ metastasis in a mouse mammary cancer model.
Autorzy :
Shibata MA; Department of Anatomy and Cell Biology, Osaka Medical College, Takatsuki, Japan.
Shibata E; Department of Molecular Innovation in Lipidology, National Cerebral & Cardiovascular Center Research Institute, Suita, Japan.
Tanaka Y; Department of Anatomy and Cell Biology, Osaka Medical College, Takatsuki, Japan.
Shiraoka C; Department of Anatomy and Cell Biology, Osaka Medical College, Takatsuki, Japan.
Kondo Y; Department of Anatomy and Cell Biology, Osaka Medical College, Takatsuki, Japan.
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Źródło :
Cancer science [Cancer Sci] 2020 Aug; Vol. 111 (8), pp. 2837-2849. Date of Electronic Publication: 2020 Jul 04.
Typ publikacji :
Journal Article
MeSH Terms :
Genetic Therapy/*methods
Mammary Neoplasms, Experimental/*therapy
Neoplasm Metastasis/*therapy
Vascular Endothelial Growth Factor C/*metabolism
Vascular Endothelial Growth Factor Receptor-3/*genetics
Animals ; Cell Line, Tumor/transplantation ; Female ; Lymphatic Vessels/pathology ; Mammary Glands, Animal/pathology ; Mammary Neoplasms, Experimental/genetics ; Mammary Neoplasms, Experimental/pathology ; Mice ; Neoplasm Invasiveness/genetics ; Neoplasm Invasiveness/prevention & control ; Neoplasm Metastasis/genetics ; Vascular Endothelial Growth Factor C/antagonists & inhibitors ; Vascular Endothelial Growth Factor Receptor-3/metabolism
Czasopismo naukowe
Tytuł :
Synchronous Pulmonary Adenocarcinomas.
Autorzy :
Pagan CA; Department of Pathology and Cell Biology, Columbia University Irving Medical Center/NewYork-Presbyterian Hospital, New York, NY.
Shu CA; Department of Medical Oncology, Columbia University Irving Medical Center/NewYork-Presbyterian Hospital, New York, NY.
Crapanzano JP; Department of Pathology and Cell Biology, Columbia University Irving Medical Center/NewYork-Presbyterian Hospital, New York, NY.
Lagos GG; Department of Medical Oncology, Columbia University Irving Medical Center/NewYork-Presbyterian Hospital, New York, NY.
Stoopler MB; Department of Medical Oncology, Columbia University Irving Medical Center/NewYork-Presbyterian Hospital, New York, NY.
Rizvi NA; Department of Medical Oncology, Columbia University Irving Medical Center/NewYork-Presbyterian Hospital, New York, NY.
Heymann JJ; Department of Pathology and Cell Biology, Columbia University Irving Medical Center/NewYork-Presbyterian Hospital, New York, NY.
Sonett JR; Department of Thoracic Surgery, Columbia University Irving Medical Center/NewYork-Presbyterian Hospital, New York, NY.
Fernandes H; Department of Pathology and Cell Biology, Columbia University Irving Medical Center/NewYork-Presbyterian Hospital, New York, NY.
Saqi A; Department of Pathology and Cell Biology, Columbia University Irving Medical Center/NewYork-Presbyterian Hospital, New York, NY.
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Źródło :
American journal of clinical pathology [Am J Clin Pathol] 2020 Jun 08; Vol. 154 (1), pp. 57-69.
Typ publikacji :
Journal Article
MeSH Terms :
Adenocarcinoma of Lung/*genetics
Lung Neoplasms/*genetics
Neoplasm Metastasis/*genetics
Neoplasms, Multiple Primary/*genetics
Adenocarcinoma of Lung/diagnosis ; Adenocarcinoma of Lung/pathology ; Aged ; Aged, 80 and over ; Female ; High-Throughput Nucleotide Sequencing ; Humans ; Lung Neoplasms/diagnosis ; Lung Neoplasms/pathology ; Male ; Middle Aged ; Neoplasm Metastasis/diagnosis ; Neoplasm Metastasis/pathology ; Neoplasms, Multiple Primary/diagnosis ; Neoplasms, Multiple Primary/pathology
Czasopismo naukowe
Tytuł :
The premise of personalized immunotherapy for cancer dormancy.
Autorzy :
Manjili MH; Department of Microbiology & Immunology, VCU School of Medicine, VCU Institute of Molecular Medicine, Massey Cancer Center, Richmond, VA, USA. .
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Źródło :
Oncogene [Oncogene] 2020 May; Vol. 39 (22), pp. 4323-4330. Date of Electronic Publication: 2020 Apr 22.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.; Review
MeSH Terms :
Immunotherapy*
Precision Medicine*
Cancer Vaccines/*therapeutic use
Neoplasm Metastasis/*prevention & control
Neoplasms/*therapy
Antigens, Neoplasm/immunology ; Apoptosis ; Cell Division ; Disease-Free Survival ; Forecasting ; Humans ; Models, Immunological ; Neoplasm Metastasis/immunology ; Neoplasm Metastasis/pathology ; Neoplasms/immunology ; Neoplasms/pathology ; Neoplastic Stem Cells/immunology ; Tumor Escape
Czasopismo naukowe
Tytuł :
Efficacy of fulvestrant 500 mg in Chinese postmenopausal women with advanced/recurrent breast cancer and factors associated with prolonged time-to-treatment failure: A retrospective case series.
Autorzy :
Huang J; Breast Medical Oncology, Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Hangzhou, P.R. China.
Huang P
Shao XY
Sun Y
Lei L
Lou CJ
Ye WW
Chen JQ
Cao WM
Huang Y
Zheng YB
Wang XJ
Chen ZH
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Źródło :
Medicine [Medicine (Baltimore)] 2020 Jul 17; Vol. 99 (29), pp. e20821.
Typ publikacji :
Journal Article; Observational Study
MeSH Terms :
Breast Neoplasms/*drug therapy
Estrogen Receptor Antagonists/*therapeutic use
Fulvestrant/*therapeutic use
Neoplasm Metastasis/*drug therapy
Postmenopause/*drug effects
Adult ; Antineoplastic Agents, Hormonal/therapeutic use ; Asian Continental Ancestry Group/ethnology ; Breast Neoplasms/mortality ; Breast Neoplasms/pathology ; Chemotherapy, Adjuvant/methods ; Female ; Follow-Up Studies ; Humans ; Middle Aged ; Neoplasm Metastasis/pathology ; Progression-Free Survival ; Retrospective Studies ; Safety ; Time-to-Treatment ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Role of long non-coding RNAs and MYC interaction in cancer metastasis: A possible target for therapeutic intervention.
Autorzy :
Fatma H; Molecular Cancer Genetics & Translational Research Lab, Section of Genetics, Department of Zoology, Aligarh Muslim University, Aligarh 202002, Uttar Pradesh, India.
Siddique HR; Molecular Cancer Genetics & Translational Research Lab, Section of Genetics, Department of Zoology, Aligarh Muslim University, Aligarh 202002, Uttar Pradesh, India. Electronic address: .
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Źródło :
Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 2020 Jul 15; Vol. 399, pp. 115056. Date of Electronic Publication: 2020 May 20.
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Review
MeSH Terms :
Neoplasm Metastasis/*genetics
Neoplasms/*genetics
Proto-Oncogene Proteins c-myc/*genetics
RNA, Long Noncoding/*genetics
Animals ; Carcinogenesis/genetics ; Carcinogenesis/pathology ; Gene Expression Regulation, Neoplastic/genetics ; Humans ; Neoplasm Metastasis/pathology ; Neoplasms/pathology
Czasopismo naukowe
Tytuł :
Multi-cancer analysis of clonality and the timing of systemic spread in paired primary tumors and metastases.
Autorzy :
Hu Z; Department of Medicine, Division of Oncology, Stanford University School of Medicine, Stanford, CA, USA.; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.; Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA, USA.
Li Z; Life Science Research Center, Core Research Facilities, Southern University of Science and Technology, Shenzhen, China.
Ma Z; Department of Medicine, Division of Oncology, Stanford University School of Medicine, Stanford, CA, USA.; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.; Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA, USA.
Curtis C; Department of Medicine, Division of Oncology, Stanford University School of Medicine, Stanford, CA, USA. .; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA. .; Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA, USA. .
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Źródło :
Nature genetics [Nat Genet] 2020 Jul; Vol. 52 (7), pp. 701-708. Date of Electronic Publication: 2020 May 18.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Clonal Evolution*
Neoplasm Metastasis*
Neoplasms/*pathology
Adult ; Aged ; Aged, 80 and over ; Breast Neoplasms/genetics ; Breast Neoplasms/pathology ; Carcinogenesis ; Chronology as Topic ; Colorectal Neoplasms/genetics ; Colorectal Neoplasms/pathology ; Humans ; Lung Neoplasms/genetics ; Lung Neoplasms/pathology ; Middle Aged ; Mutation ; Neoplasm Seeding ; Neoplasms/genetics ; Whole Exome Sequencing
Czasopismo naukowe
Tytuł :
Loss of myeloid-specific lamin A/C drives lung metastasis through Gfi-1 and C/EBPε-mediated granulocytic differentiation.
Autorzy :
Ishii H; Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland.
Park WY; Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland.
So J; Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland.
Kuhn S; CCR Collaborative Bioinformatics Resource, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland.; Advanced Biomedical Computational Science, Frederick National Laboratory for Cancer Research Sponsored by the National Cancer Institute, NIH, Frederick, Maryland.
Koparde VN; CCR Collaborative Bioinformatics Resource, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland.; Advanced Biomedical Computational Science, Frederick National Laboratory for Cancer Research Sponsored by the National Cancer Institute, NIH, Frederick, Maryland.
Pang Y; Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland.
Greten TF; Thoracic and Gastrointestinal Malignancies Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland.
Hollander MC; Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland.
Yang L; Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland.
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Źródło :
Molecular carcinogenesis [Mol Carcinog] 2020 Jul; Vol. 59 (7), pp. 679-690. Date of Electronic Publication: 2020 Jan 07.
Typ publikacji :
Journal Article; Research Support, N.I.H., Intramural
MeSH Terms :
CCAAT-Enhancer-Binding Proteins/*genetics
Cell Differentiation/*genetics
Lamin Type A/*genetics
Lung Neoplasms/*genetics
Myeloid Cells/*pathology
Neoplasm Metastasis/*genetics
Proto-Oncogene Proteins/*genetics
Repressor Proteins/*genetics
Animals ; Cells, Cultured ; Chemokines/genetics ; Disease Models, Animal ; Female ; Granulocytes/pathology ; Humans ; Inflammation/genetics ; Inflammation/pathology ; Leukocytes, Mononuclear/pathology ; Lung Neoplasms/pathology ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Mice, Knockout ; Neoplasm Metastasis/pathology ; Triple Negative Breast Neoplasms/genetics ; Triple Negative Breast Neoplasms/pathology ; Tumor Microenvironment/genetics ; Up-Regulation/genetics
Czasopismo naukowe

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