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Wyszukujesz frazę ""Neoplasm Metastasis"" wg kryterium: Temat


Tytuł:
Cathepsin D promotes polarization of tumor-associated macrophages and metastasis through TGFBI-CCL20 signaling.
Autorzy:
Lee SG; Department of Immunology, School of Medicine, Keimyung University, Daegu, Republic of Korea.; Department of Microbiology, Immunology, and Cancer Biology, University of Virginia, Charlottesville, VA, USA.
Woo SM; Department of Immunology, School of Medicine, Keimyung University, Daegu, Republic of Korea.
Seo SU; Department of Immunology, School of Medicine, Keimyung University, Daegu, Republic of Korea.
Lee CH; Department of Molecular Medicine, CMRI, Exosome Convergence Research Center (ECRC), School of Medicine, Kyungpook National University, Daegu, Republic of Korea.
Baek MC; Department of Molecular Medicine, CMRI, Exosome Convergence Research Center (ECRC), School of Medicine, Kyungpook National University, Daegu, Republic of Korea.
Jang SH; School of Life Sciences, Gwangju Institute of Science and Technology, Gwangju, Korea.
Park ZY; School of Life Sciences, Gwangju Institute of Science and Technology, Gwangju, Korea.
Yook S; Department of Biopharmaceutical Convergence, Sungkyunkwan University, Suwon, Republic of Korea.
Nam JO; Department of Food Science and Biotechnology, Kyungpook National University, Daegu, Republic of Korea.
Kwon TK; Department of Immunology, School of Medicine, Keimyung University, Daegu, Republic of Korea. .; Center for Forensic Pharmaceutical Science, Keimyung University, Daegu, Republic of Korea. .
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Źródło:
Experimental & molecular medicine [Exp Mol Med] 2024 Feb; Vol. 56 (2), pp. 383-394. Date of Electronic Publication: 2024 Feb 01.
Typ publikacji:
Journal Article
MeSH Terms:
Cathepsin D*/genetics
Cathepsin D*/metabolism
Chemokine CCL20*
Tumor-Associated Macrophages*
Cell Polarity*
Transforming Growth Factor beta*/metabolism
Neoplasm Metastasis*
Biological Transport ; Signal Transduction ; Female ; Animals ; Mice ; Mice, SCID
Czasopismo naukowe
Tytuł:
Phagocytosis-initiated tumor hybrid cells acquire a c-Myc-mediated quasi-polarization state for immunoevasion and distant dissemination.
Autorzy:
Chou CW; Department of Molecular Medicine, University of Texas Health Science Center, San Antonio, TX, 78229, USA.
Hung CN; Department of Molecular Medicine, University of Texas Health Science Center, San Antonio, TX, 78229, USA.
Chiu CH; Department of Molecular Medicine, University of Texas Health Science Center, San Antonio, TX, 78229, USA.
Tan X; Department of Molecular Medicine, University of Texas Health Science Center, San Antonio, TX, 78229, USA.
Chen M; Department of Molecular Medicine, University of Texas Health Science Center, San Antonio, TX, 78229, USA.
Chen CC; Department of Pathology, Ditmanson Medical Foundation Chia-Yi Christian Hospital, Chiayi, Taiwan.
Saeed M; Department of Molecular Medicine, University of Texas Health Science Center, San Antonio, TX, 78229, USA.
Hsu CW; Department of Pathology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Liss MA; Department of Urology, University of Texas Health Science Center, San Antonio, TX, 78229, USA.; Mays Cancer Center, University of Texas Health Science Center, San Antonio, TX, 78229, USA.
Wang CM; Department of Molecular Medicine, University of Texas Health Science Center, San Antonio, TX, 78229, USA.
Lai Z; Department of Molecular Medicine, University of Texas Health Science Center, San Antonio, TX, 78229, USA.
Alvarez N; Department of Molecular Medicine, University of Texas Health Science Center, San Antonio, TX, 78229, USA.
Osmulski PA; Department of Molecular Medicine, University of Texas Health Science Center, San Antonio, TX, 78229, USA.
Gaczynska ME; Department of Molecular Medicine, University of Texas Health Science Center, San Antonio, TX, 78229, USA.
Lin LL; Department of Molecular Medicine, University of Texas Health Science Center, San Antonio, TX, 78229, USA.
Ortega V; Department of Pathology and Laboratory Medicine, University of Texas Health Science Center, San Antonio, TX, 78229, USA.
Kirma NB; Department of Molecular Medicine, University of Texas Health Science Center, San Antonio, TX, 78229, USA.
Xu K; Department of Molecular Medicine, University of Texas Health Science Center, San Antonio, TX, 78229, USA.
Liu Z; Department of Molecular Medicine, University of Texas Health Science Center, San Antonio, TX, 78229, USA.
Kumar AP; Department of Molecular Medicine, University of Texas Health Science Center, San Antonio, TX, 78229, USA.; Department of Urology, University of Texas Health Science Center, San Antonio, TX, 78229, USA.; Mays Cancer Center, University of Texas Health Science Center, San Antonio, TX, 78229, USA.
Taverna JA; Department of Molecular Medicine, University of Texas Health Science Center, San Antonio, TX, 78229, USA.; Mays Cancer Center, University of Texas Health Science Center, San Antonio, TX, 78229, USA.; Department of Medicine, University of Texas Health Science Center, San Antonio, TX, 78229, USA.
Velagaleti GVN; Department of Pathology and Laboratory Medicine, University of Texas Health Science Center, San Antonio, TX, 78229, USA.
Chen CL; Department of Molecular Medicine, University of Texas Health Science Center, San Antonio, TX, 78229, USA. .; Biobehavior Laboratory, School of Nursing, University of Texas Health Science Center, San Antonio, TX, 78229, USA. .
Zhang Z; Department of Molecular Medicine, University of Texas Health Science Center, San Antonio, TX, 78229, USA. .
Huang TH; Department of Molecular Medicine, University of Texas Health Science Center, San Antonio, TX, 78229, USA. .; Mays Cancer Center, University of Texas Health Science Center, San Antonio, TX, 78229, USA. .
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Źródło:
Nature communications [Nat Commun] 2023 Oct 17; Vol. 14 (1), pp. 6569. Date of Electronic Publication: 2023 Oct 17.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
CD47 Antigen*/metabolism
Macrophages*/metabolism
Phagocytosis*
Proto-Oncogene Proteins c-myc*/genetics
Proto-Oncogene Proteins c-myc*/immunology
Tumor Escape*/genetics
Tumor Escape*/immunology
Neoplasm Metastasis*/genetics
Neoplasm Metastasis*/immunology
Humans ; Male ; Carrier Proteins ; Prostatic Neoplasms/genetics ; Prostatic Neoplasms/immunology ; Prostatic Neoplasms/pathology ; Signal Transduction ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł:
Nickel chloride promotes lung cancer invasion and metastasis by up-regulating the expression of E3 ubiquitin ligase TRIM31 through the IL-6/STAT3 signaling axis.
Autorzy:
Lu Y; College of Earth and Environmental Sciences, School of Basci Medical Sciences, The First Hospital of Lanzhou University, Lanzhou University, Lanzhou, Gansu, China. Electronic address: .
Su F; Department of Oncology, The First Hospital of Lanzhou University, Lanzhou, Gansu, China.
Cheng Z; School of Public Health and Emergency Management, Southern University of Science and Technology, Shenzhen, China.
Yang J; College of Earth and Environmental Sciences, Department of Epidemiology and Statistics, Lanzhou university, Lanzhou, Gansu, China.
Dai H; Department of Oncology, The First Hospital of Lanzhou University, Lanzhou, Gansu, China.
Yang J; Department of Oncology, The First Hospital of Lanzhou University, Lanzhou, Gansu, China.
Zhang T; Department of Oncology, The First Hospital of Lanzhou University, Lanzhou, Gansu, China. Electronic address: .
Bai Y; College of Earth and Environmental Sciences, Department of Epidemiology and Statistics, Lanzhou university, Lanzhou, Gansu, China. Electronic address: .
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Źródło:
Life sciences [Life Sci] 2023 Nov 01; Vol. 332, pp. 122111. Date of Electronic Publication: 2023 Sep 19.
Typ publikacji:
Journal Article
MeSH Terms:
Lung Neoplasms*/chemically induced
Nickel*/adverse effects
Ubiquitin-Protein Ligases*/genetics
Ubiquitin-Protein Ligases*/metabolism
Neoplasm Metastasis*
Humans ; Interleukin-6/metabolism ; STAT3 Transcription Factor/metabolism ; Tripartite Motif Proteins/metabolism ; Tumor Suppressor Protein p53/metabolism ; Ubiquitination
Czasopismo naukowe
Tytuł:
Cellular and molecular characteristics of the premetastatic niches.
Autorzy:
Liu H; Department of Otolaryngology, Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, China.; National Human Diseases Animal Model Resource Center, The Institute of Laboratory Animal Science, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.; NHC Key Laboratory of Human Disease Comparative Medicine, Beijing Engineering Research Center for Experimental Animal Models of Human Critical Diseases, Beijing, China.; Beijing Engineering Research Center for Experimental Animal Models of Human Critical Diseases, Beijing, China.
Zhang G; National Human Diseases Animal Model Resource Center, The Institute of Laboratory Animal Science, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.; NHC Key Laboratory of Human Disease Comparative Medicine, Beijing Engineering Research Center for Experimental Animal Models of Human Critical Diseases, Beijing, China.; Beijing Engineering Research Center for Experimental Animal Models of Human Critical Diseases, Beijing, China.
Gao R; National Human Diseases Animal Model Resource Center, The Institute of Laboratory Animal Science, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.; NHC Key Laboratory of Human Disease Comparative Medicine, Beijing Engineering Research Center for Experimental Animal Models of Human Critical Diseases, Beijing, China.; Beijing Engineering Research Center for Experimental Animal Models of Human Critical Diseases, Beijing, China.
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Źródło:
Animal models and experimental medicine [Animal Model Exp Med] 2023 Oct; Vol. 6 (5), pp. 399-408.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Neoplasms*/genetics
Neoplasms*/pathology
Neoplasms*/therapy
Neoplasm Metastasis*/pathology
Humans
Czasopismo naukowe
Tytuł:
Histone deacetylase inhibitors inhibit lung adenocarcinoma metastasis via HDAC2/YY1 mediated downregulation of Cdh1.
Autorzy:
Wang D; Department of Gastrointestinal Surgery, The Affiliated Changzhou, No. 2 People's Hospital of Nanjing Medical University, Changzhou, 213004, Jiangsu, China.; Changzhou Medical Center of Nanjing Medical University, Changzhou, 213004, Jiangsu, China.
Yang Y; Institute of Burn Research, The First Affiliated Hospital, State Key Lab of Trauma, Burn and Combined Injury, Chongqing Key Laboratory for Disease Proteomics, Third Military Medical University (Army Medical University), Chongqing, 400038, China.
Cao Y; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, 200241, China.
Meng M; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, 200241, China.
Wang X; Henan Provincial Chest Hospital, Zhengzhou, 450000, Henan, China.
Zhang Z; Henan Provincial Chest Hospital, Zhengzhou, 450000, Henan, China.
Fu W; Henan Provincial Chest Hospital, Zhengzhou, 450000, Henan, China.
Duan S; Henan Provincial People's Hospital, Henan Eye Hospital, Henan Eye Institute, Zhengzhou University People's Hospital, Henan University People's Hospital, Zhengzhou, 450003, Henan, China. .
Tang L; Department of Gastrointestinal Surgery, The Affiliated Changzhou, No. 2 People's Hospital of Nanjing Medical University, Changzhou, 213004, Jiangsu, China. .; Changzhou Medical Center of Nanjing Medical University, Changzhou, 213004, Jiangsu, China. .
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Źródło:
Scientific reports [Sci Rep] 2023 Jul 26; Vol. 13 (1), pp. 12069. Date of Electronic Publication: 2023 Jul 26.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Histone Deacetylase Inhibitors*/pharmacology
Histone Deacetylase Inhibitors*/therapeutic use
Adenocarcinoma of Lung*/drug therapy
Adenocarcinoma of Lung*/enzymology
Adenocarcinoma of Lung*/metabolism
Adenocarcinoma of Lung*/pathology
Histone Deacetylase 2*/antagonists & inhibitors
Histone Deacetylase 2*/metabolism
YY1 Transcription Factor*/metabolism
Cadherins*/genetics
Cadherins*/metabolism
Antigens, CD*/metabolism
Neoplasm Metastasis*/drug therapy
Neoplasm Metastasis*/pathology
Neoplasm Metastasis*/prevention & control
Humans ; Animals ; Mice ; Female ; Cell Movement/drug effects ; Butyric Acid/pharmacology ; Butyric Acid/therapeutic use ; Transforming Growth Factor beta/metabolism ; Epithelial-Mesenchymal Transition/drug effects ; Protein Binding ; Transcription, Genetic ; Gene Expression Regulation, Neoplastic
Czasopismo naukowe
Tytuł:
A vertebral skeletal stem cell lineage driving metastasis.
Autorzy:
Sun J; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA.
Hu L; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA.; Department of Spine Surgery, Hospital for Special Surgery, New York, NY, USA.
Bok S; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA.
Yallowitz AR; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA.
Cung M; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA.
McCormick J; Flow Cytometry Core Facility, Weill Cornell Medicine, New York, NY, USA.
Zheng LJ; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA.
Debnath S; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA.
Niu Y; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA.
Tan AY; Genomics Resources Core Facility, Weill Cornell Medicine, New York, NY, USA.
Lalani S; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA.
Morse KW; Department of Spine Surgery, Hospital for Special Surgery, New York, NY, USA.
Shinn D; Department of Spine Surgery, Hospital for Special Surgery, New York, NY, USA.; Weill Cornell Medical College, New York, NY, USA.
Pajak A; Department of Spine Surgery, Hospital for Special Surgery, New York, NY, USA.
Hammad M; Research Division, Hospital for Special Surgery, New York, NY, USA.
Suhardi VJ; Research Division, Hospital for Special Surgery, New York, NY, USA.; Department of Orthopedic Surgery, Hospital for Special Surgery, New York, NY, USA.
Li Z; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA.
Li N; State Key Laboratory of Cellular Stress Biology, School of Medicine, Xiamen University, Xiamen, China.
Wang L; Institute of Microsurgery on Extremities, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
Zou W; Institute of Microsurgery on Extremities, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.; State Key Laboratory of Cell Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China.
Mittal V; Department of Cardiothoracic Surgery, Weill Cornell Medicine, New York, NY, USA.
Bostrom MPG; Research Division, Hospital for Special Surgery, New York, NY, USA.; Department of Orthopedic Surgery, Hospital for Special Surgery, New York, NY, USA.; Department of Orthopedic Surgery, Weill Cornell Medicine, New York, NY, USA.
Xu R; State Key Laboratory of Cellular Stress Biology, School of Medicine, Xiamen University, Xiamen, China.
Iyer S; Department of Spine Surgery, Hospital for Special Surgery, New York, NY, USA.
Greenblatt MB; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA. .; Research Division, Hospital for Special Surgery, New York, NY, USA. .
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Źródło:
Nature [Nature] 2023 Sep; Vol. 621 (7979), pp. 602-609. Date of Electronic Publication: 2023 Sep 13.
Typ publikacji:
Journal Article
MeSH Terms:
Breast Neoplasms*/pathology
Cell Lineage*
Neoplasm Metastasis*/pathology
Spine*/cytology
Spine*/pathology
Stem Cells*/cytology
Stem Cells*/metabolism
Stem Cells*/pathology
Humans ; Cell Differentiation ; Cell Self Renewal ; Osteoblasts/cytology ; Osteoblasts/pathology ; Biomarkers
Czasopismo naukowe
Tytuł:
Engineered Macrophages-Based uPA-Scavenger Load Gemcitabine to Prompt Robust Treating Cancer Metastasis.
Autorzy:
Rao Z; School of Life Science and Technology, Xidian University, Xi'an, Shaanxi, 710071, P. R. China.; Engineering Research Center of Molecular & Neuroimaging, Ministry of Education, Xi'an, Shaanxi, 710071, P. R. China.
Lu C; School of Life Science and Technology, Xidian University, Xi'an, Shaanxi, 710071, P. R. China.; Engineering Research Center of Molecular & Neuroimaging, Ministry of Education, Xi'an, Shaanxi, 710071, P. R. China.
Fan H; School of Life Science and Technology, Xidian University, Xi'an, Shaanxi, 710071, P. R. China.; Engineering Research Center of Molecular & Neuroimaging, Ministry of Education, Xi'an, Shaanxi, 710071, P. R. China.
Du F; School of Life Science and Technology, Xidian University, Xi'an, Shaanxi, 710071, P. R. China.; Engineering Research Center of Molecular & Neuroimaging, Ministry of Education, Xi'an, Shaanxi, 710071, P. R. China.
Zhu Y; School of Life Science and Technology, Xidian University, Xi'an, Shaanxi, 710071, P. R. China.; Engineering Research Center of Molecular & Neuroimaging, Ministry of Education, Xi'an, Shaanxi, 710071, P. R. China.
Xia Y; School of Life Science and Technology, Xidian University, Xi'an, Shaanxi, 710071, P. R. China.; Engineering Research Center of Molecular & Neuroimaging, Ministry of Education, Xi'an, Shaanxi, 710071, P. R. China.
Wang Z; Department of Medical Oncology, Xiamen Branch, Zhongshan Hospital, Fudan University, Xiamen, 361015, P. R. China.
Ning P; School of Life Science and Technology, Xidian University, Xi'an, Shaanxi, 710071, P. R. China.; Engineering Research Center of Molecular & Neuroimaging, Ministry of Education, Xi'an, Shaanxi, 710071, P. R. China.
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Źródło:
Advanced healthcare materials [Adv Healthc Mater] 2023 Jul; Vol. 12 (18), pp. e2203356. Date of Electronic Publication: 2023 Mar 31.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Macrophages*
Neoplasm Metastasis*/drug therapy
Urokinase-Type Plasminogen Activator*/metabolism
Caproates*/pharmacology
Animals ; Mice ; Nanoparticles ; Neoplasms, Experimental ; Cell Line, Tumor ; Mice, Inbred BALB C ; Female
Czasopismo naukowe
Tytuł:
Ez-Metastasizing: The Crucial Roles of Ezrin in Metastasis.
Autorzy:
Buenaventura RGM; Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Merlino G; Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Yu Y; Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
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Źródło:
Cells [Cells] 2023 Jun 14; Vol. 12 (12). Date of Electronic Publication: 2023 Jun 14.
Typ publikacji:
Journal Article; Research Support, N.I.H., Intramural; Review
MeSH Terms:
Cell Adhesion*/genetics
Cell Adhesion*/physiology
Cytoskeletal Proteins*/metabolism
Cytoskeleton*/metabolism
Neoplasm Metastasis*/genetics
Neoplasm Metastasis*/physiopathology
Czasopismo naukowe
Tytuł:
Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA.
Autorzy:
Abbosh C; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK. .
Frankell AM; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.
Harrison T; Invitae, San Francisco, CA, USA.
Kisistok J; Department of Molecular Medicine, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.; Bioinformatics Research Centre, Aarhus University, Aarhus, Denmark.
Garnett A; Invitae, San Francisco, CA, USA.
Johnson L; Invitae, San Francisco, CA, USA.
Veeriah S; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.
Moreau M; Invitae, San Francisco, CA, USA.
Chesh A; Invitae, San Francisco, CA, USA.
Chaunzwa TL; Artificial Intelligence in Medicine (AIM) Program, Mass General Brigham, Harvard Medical School, Boston, MA, USA.; Department of Radiation Oncology, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
Weiss J; Artificial Intelligence in Medicine (AIM) Program, Mass General Brigham, Harvard Medical School, Boston, MA, USA.; Department of Radiation Oncology, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.; Department of Radiology, Freiburg University Hospital, Freiburg, Germany.
Schroeder MR; Invitae, San Francisco, CA, USA.
Ward S; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Advanced Sequencing Facility, The Francis Crick Institute, London, UK.
Grigoriadis K; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.
Shahpurwalla A; Invitae, San Francisco, CA, USA.
Litchfield K; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Tumour Immunogenomics and Immunosurveillance Laboratory, University College London Cancer Institute, London, UK.
Puttick C; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.
Biswas D; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Bill Lyons Informatics Centre, University College London Cancer Institute, London, UK.
Karasaki T; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Metastasis Laboratory, University College London Cancer Institute, London, UK.
Black JRM; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.
Martínez-Ruiz C; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.
Bakir MA; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.
Pich O; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.
Watkins TBK; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.
Lim EL; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.
Huebner A; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.
Moore DA; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Department of Cellular Pathology, University College London Hospitals, London, UK.
Godin-Heymann N; AstraZeneca, Cambridge, UK.
L'Hernault A; AstraZeneca, Cambridge, UK.
Bye H; AstraZeneca, Cambridge, UK.
Odell A; Invitae, San Francisco, CA, USA.
Roberts P; Invitae, San Francisco, CA, USA.
Gomes F; The Christie NHS Foundation Trust, Manchester, UK.
Patel AJ; University Hospital Birmingham NHS Foundation Trust, Birmingham, UK.
Manzano E; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.
Hiley CT; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.
Carey N; Cancer Research Centre, University of Leicester, Leicester, UK.
Riley J; Cancer Research Centre, University of Leicester, Leicester, UK.
Cook DE; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.
Hodgson D; AstraZeneca, Cambridge, UK.
Stetson D; AstraZeneca, Waltham, MA, USA.
Barrett JC; AstraZeneca, Waltham, MA, USA.
Kortlever RM; Department of Biochemistry, University of Cambridge, Cambridge, UK.
Evan GI; Department of Biochemistry, University of Cambridge, Cambridge, UK.
Hackshaw A; Cancer Research UK & UCL Cancer Trials Centre, London, UK.
Daber RD; Invitae, San Francisco, CA, USA.
Shaw JA; Cancer Research Centre, University of Leicester, Leicester, UK.
Aerts HJWL; Artificial Intelligence in Medicine (AIM) Program, Mass General Brigham, Harvard Medical School, Boston, MA, USA.; Department of Radiation Oncology, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.; Radiology and Nuclear Medicine, CARIM & GROW, Maastricht University, Maastricht, The Netherlands.
Licon A; Invitae, San Francisco, CA, USA.
Stahl J; Invitae, San Francisco, CA, USA.
Jamal-Hanjani M; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Metastasis Laboratory, University College London Cancer Institute, London, UK.; Department of Oncology, University College London Hospitals, London, UK.
Birkbak NJ; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Department of Molecular Medicine, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.; Bioinformatics Research Centre, Aarhus University, Aarhus, Denmark.
McGranahan N; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK. .; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK. .
Swanton C; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK. .; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK. .; Department of Oncology, University College London Hospitals, London, UK. .
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Corporate Authors:
TRACERx Consortium
Źródło:
Nature [Nature] 2023 Apr; Vol. 616 (7957), pp. 553-562. Date of Electronic Publication: 2023 Apr 13.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Biomarkers, Tumor*/blood
Biomarkers, Tumor*/genetics
Carcinoma, Non-Small-Cell Lung*/blood
Carcinoma, Non-Small-Cell Lung*/genetics
Carcinoma, Non-Small-Cell Lung*/pathology
Circulating Tumor DNA*/blood
Circulating Tumor DNA*/genetics
Lung Neoplasms*/blood
Lung Neoplasms*/genetics
Lung Neoplasms*/pathology
Mutation*
Neoplasm Metastasis*/diagnosis
Neoplasm Metastasis*/genetics
Neoplasm Metastasis*/pathology
Small Cell Lung Carcinoma*/pathology
Humans ; Cohort Studies ; Neoplasm Recurrence, Local/diagnosis ; Neoplasm Recurrence, Local/genetics ; Neoplasm Recurrence, Local/pathology ; Phylogeny ; Liquid Biopsy
Czasopismo naukowe
Tytuł:
STING inhibits the reactivation of dormant metastasis in lung adenocarcinoma.
Autorzy:
Hu J; Cancer Biology and Genetics Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Sánchez-Rivera FJ; Cancer Biology and Genetics Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA.
Wang Z; Cancer Biology and Genetics Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Johnson GN; Cancer Biology and Genetics Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Ho YJ; Cancer Biology and Genetics Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Ganesh K; Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Umeda S; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Gan S; Cancer Biology and Genetics Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Mujal AM; Immunology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Delconte RB; Immunology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Hampton JP; Cancer Biology and Genetics Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Zhao H; Antitumor Assessment Core, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Kottapalli S; Computational and Systems Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
de Stanchina E; Antitumor Assessment Core, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Iacobuzio-Donahue CA; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Pe'er D; Computational and Systems Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; The Alan and Sandra Gerry Metastasis and Tumor Ecosystems Center, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Howard Hughes Medical Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Lowe SW; Cancer Biology and Genetics Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Howard Hughes Medical Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Sun JC; Immunology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Massagué J; Cancer Biology and Genetics Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA. .; The Alan and Sandra Gerry Metastasis and Tumor Ecosystems Center, Memorial Sloan Kettering Cancer Center, New York, NY, USA. .
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Źródło:
Nature [Nature] 2023 Apr; Vol. 616 (7958), pp. 806-813. Date of Electronic Publication: 2023 Mar 29.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Lung Neoplasms*/drug therapy
Lung Neoplasms*/genetics
Lung Neoplasms*/immunology
Lung Neoplasms*/pathology
Neoplasm Metastasis*/drug therapy
Neoplasm Metastasis*/genetics
Neoplasm Metastasis*/immunology
Neoplasm Metastasis*/pathology
Animals ; Mice ; Adenocarcinoma of Lung/drug therapy ; Adenocarcinoma of Lung/genetics ; Adenocarcinoma of Lung/immunology ; Adenocarcinoma of Lung/pathology ; Cell Cycle ; Neoplasm Recurrence, Local/drug therapy ; T-Lymphocytes/immunology ; Transforming Growth Factor beta ; Killer Cells, Natural/immunology
Czasopismo naukowe
Tytuł:
The evolution of non-small cell lung cancer metastases in TRACERx.
Autorzy:
Al Bakir M; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.
Huebner A; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.
Martínez-Ruiz C; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.
Grigoriadis K; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.
Watkins TBK; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.
Pich O; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.
Moore DA; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Department of Cellular Pathology, University College London Hospitals, London, UK.
Veeriah S; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.
Ward S; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Advanced Sequencing Facility, The Francis Crick Institute, London, UK.
Laycock J; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.
Johnson D; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.
Rowan A; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.
Razaq M; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.
Akther M; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.
Naceur-Lombardelli C; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.
Prymas P; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.
Toncheva A; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.
Hessey S; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Metastasis Laboratory, University College London Cancer Institute, London, UK.; Computational Cancer Genomics Research Group, University College London Cancer Institute, London, UK.
Dietzen M; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.
Colliver E; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.
Frankell AM; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.
Bunkum A; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Metastasis Laboratory, University College London Cancer Institute, London, UK.; Computational Cancer Genomics Research Group, University College London Cancer Institute, London, UK.
Lim EL; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.
Karasaki T; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Metastasis Laboratory, University College London Cancer Institute, London, UK.
Abbosh C; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.
Hiley CT; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.
Hill MS; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.
Cook DE; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.
Wilson GA; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.
Salgado R; Department of Pathology, ZAS Hospitals, Antwerp, Belgium.; Division of Research, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.
Nye E; Experimental Histopathology, The Francis Crick Institute, London, UK.
Stone RK; Experimental Histopathology, The Francis Crick Institute, London, UK.
Fennell DA; University of Leicester, Leicester, UK.; University Hospitals of Leicester NHS Trust, Leicester, UK.
Price G; Department of Medical Oncology, Aberdeen Royal Infirmary NHS Grampian, Aberdeen, UK.; University of Aberdeen, Aberdeen, UK.
Kerr KM; University of Aberdeen, Aberdeen, UK.; Department of Pathology, Aberdeen Royal Infirmary NHS Grampian, Aberdeen, UK.
Naidu B; Birmingham Acute Care Research Group, Institute of Inflammation and Ageing, University of Birmingham, Birmingham, UK.
Middleton G; University Hospital Birmingham NHS Foundation Trust, Birmingham, UK.; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK.
Summers Y; Division of Cancer Sciences, The University of Manchester and The Christie NHS Foundation Trust, Manchester, UK.
Lindsay CR; Division of Cancer Sciences, The University of Manchester and The Christie NHS Foundation Trust, Manchester, UK.
Blackhall FH; Division of Cancer Sciences, The University of Manchester and The Christie NHS Foundation Trust, Manchester, UK.
Cave J; Department of Oncology, University Hospital Southampton NHS Foundation Trust, Southampton, UK.
Blyth KG; School of Cancer Sciences, University of Glasgow, Glasgow, UK.; Cancer Research UK Beatson Institute, Glasgow, UK.; Queen Elizabeth University Hospital, Glasgow, UK.
Nair A; Department of Radiology, University College London Hospitals, London, UK.; UCL Respiratory, Department of Medicine, University College London, London, UK.
Ahmed A; Department of Radiology, University College London Hospitals, London, UK.
Taylor MN; Department of Radiology, University College London Hospitals, London, UK.
Procter AJ; Department of Radiology, University College London Hospitals, London, UK.
Falzon M; Department of Cellular Pathology, University College London Hospitals, London, UK.
Lawrence D; Department of Thoracic Surgery, University College London Hospital NHS Trust, London, UK.
Navani N; Lungs for Living Research Centre, UCL Respiratory, University College London, London, UK.; Department of Thoracic Medicine, University College London Hospitals, London, UK.
Thakrar RM; Lungs for Living Research Centre, UCL Respiratory, University College London, London, UK.; Department of Thoracic Medicine, University College London Hospitals, London, UK.
Janes SM; Lungs for Living Research Centre, UCL Respiratory, University College London, London, UK.
Papadatos-Pastos D; Department of Oncology, University College London Hospitals, London, UK.
Forster MD; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Department of Oncology, University College London Hospitals, London, UK.
Lee SM; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Department of Oncology, University College London Hospitals, London, UK.
Ahmad T; Department of Oncology, University College London Hospitals, London, UK.
Quezada SA; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Immune Regulation and Tumour Immunotherapy Group, Cancer Immunology Unit, Research Department of Haematology, University College London Cancer Institute, London, UK.
Peggs KS; Department of Haematology, University College London Hospitals, London, UK.; Cancer Immunology Unit, Research Department of Haematology, University College London Cancer Institute, London, UK.
Van Loo P; Cancer Genomics Laboratory, The Francis Crick Institute, London, UK.; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Dive C; Cancer Research UK Manchester Institute Cancer Biomarker Centre, University of Manchester, Manchester, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University of Manchester, Manchester, UK.
Hackshaw A; Cancer Research UK & UCL Cancer Trials Centre, London, UK.
Birkbak NJ; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Department of Molecular Medicine, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.; Bioinformatics Research Centre, Aarhus University, Aarhus, Denmark.
Zaccaria S; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Computational Cancer Genomics Research Group, University College London Cancer Institute, London, UK.
Jamal-Hanjani M; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK. .; Cancer Metastasis Laboratory, University College London Cancer Institute, London, UK. .; Department of Oncology, University College London Hospitals, London, UK. .
McGranahan N; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK. .; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK. .
Swanton C; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK. .; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK. .; Department of Oncology, University College London Hospitals, London, UK. .
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Corporate Authors:
TRACERx Consortium
Źródło:
Nature [Nature] 2023 Apr; Vol. 616 (7957), pp. 534-542. Date of Electronic Publication: 2023 Apr 12.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Carcinoma, Non-Small-Cell Lung*/pathology
Clonal Evolution*
Clone Cells*/pathology
Evolution, Molecular*
Lung Neoplasms*/pathology
Neoplasm Metastasis*/diagnosis
Neoplasm Metastasis*/pathology
Humans ; Cohort Studies ; Disease Progression ; Neoplasm Recurrence, Local
Czasopismo naukowe
Tytuł:
Comprehensive analysis of Japanese nationwide cohort data of particle beam therapy for pulmonary, liver and lymph node oligometastases: particle beam therapy versus high-precision X-ray radiotherapy.
Autorzy:
Aibe N; Department of Radiology, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan.
Ogino H; Department of Radiation Oncology, Nagoya Proton Therapy Center, Nagoya City University West Medical Center, Nagoya 462-8508, Japan.
Wakatsuki M; QST Hospital, National Institutes for Quantum Science and Technology, Chiba 263-8555, Japan.
Fujikawa K; Department of Biostatistics, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan.
Teramukai S; Department of Biostatistics, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan.
Fukumitsu N; Department of Radiation Oncology, Kobe Proton Center, Hyogo 650-0047, Japan.
Shiba S; Department of Radiation Oncology, Gunma University Graduate School of Medicine, Gunma 371-8511, Japan.
Yamamoto N; QST Hospital, National Institutes for Quantum Science and Technology, Chiba 263-8555, Japan.
Nomoto A; QST Hospital, National Institutes for Quantum Science and Technology, Chiba 263-8555, Japan.
Ono T; Department of Radiation Oncology, Yamagata University, Faculty of Medicine, Yamagata 990-9585, Japan.
Oguri M; Department of Radiation Oncology, Nagoya Proton Therapy Center, Nagoya City University West Medical Center, Nagoya 462-8508, Japan.
Yamaguchi H; Department of Radiology, Southern Tohoku Proton Therapy Center, Koriyama City, Fukushima 963-8052, Japan.
Numajiri H; Department of Radiation Oncology, University of Tsukuba, Ibaraki 305-8550, Japan.
Shibuya K; Department of Radiation Oncology, Gunma University Graduate School of Medicine, Gunma 371-8511, Japan.
Okazaki S; Department of Radiation Oncology, Gunma University Graduate School of Medicine, Gunma 371-8511, Japan.
Miyasaka Y; Department of Radiation Oncology, Gunma University Graduate School of Medicine, Gunma 371-8511, Japan.
Okonogi N; QST Hospital, National Institutes for Quantum Science and Technology, Chiba 263-8555, Japan.
Murata K; QST Hospital, National Institutes for Quantum Science and Technology, Chiba 263-8555, Japan.
Tatebe H; Proton Therapy Center, Fukui Prefectural Hospital, Fukui 910-0846, Japan.
Motegi A; Department of Radiation Oncology, National Cancer Center Hospital East, Chiba 277-8577, Japan.
Okimoto T; Department of Radiology, Hyogo Ion Beam Medical Center, Hyogo, Japan.
Yoshino T; Department of Gastrointestinal Oncology, National Cancer Center Hospital East, Chiba, Japan.
Mandai M; Department of Gynecology and Obstetrics, Kyoto University Graduate School of Medicine, Kyoto 606-8501, Japan.
Katoh N; Department of Radiation Oncology, Hokkaido University Faculty of Medicine, Hokkaido 060-0808, Japan.
Tsuji H; QST Hospital, National Institutes for Quantum Science and Technology, Chiba 263-8555, Japan.
Sakurai H; Department of Radiation Oncology, University of Tsukuba, Ibaraki 305-8550, Japan.
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Źródło:
Journal of radiation research [J Radiat Res] 2023 Jun 16; Vol. 64 (Supplement_1), pp. i69-i83.
Typ publikacji:
Systematic Review; Journal Article
MeSH Terms:
Radiosurgery*
Neoplasm Metastasis*/radiotherapy
Humans ; Cohort Studies ; East Asian People ; Liver ; Retrospective Studies ; Treatment Outcome ; X-Rays
Czasopismo naukowe
Tytuł:
Pan-cancer whole-genome comparison of primary and metastatic solid tumours.
Autorzy:
Martínez-Jiménez F; Center for Molecular Medicine, Oncode Institute, University Medical Center Utrecht, Utrecht, The Netherlands.; Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain.; Hartwig Medical Foundation, Amsterdam, The Netherlands.
Movasati A; Center for Molecular Medicine, Oncode Institute, University Medical Center Utrecht, Utrecht, The Netherlands.
Brunner SR; Center for Molecular Medicine, Oncode Institute, University Medical Center Utrecht, Utrecht, The Netherlands.
Nguyen L; Center for Molecular Medicine, Oncode Institute, University Medical Center Utrecht, Utrecht, The Netherlands.; Hartwig Medical Foundation Australia, Sydney, New South Wales, Australia.
Priestley P; Hartwig Medical Foundation Australia, Sydney, New South Wales, Australia.
Cuppen E; Center for Molecular Medicine, Oncode Institute, University Medical Center Utrecht, Utrecht, The Netherlands. .; Hartwig Medical Foundation, Amsterdam, The Netherlands. .
Van Hoeck A; Center for Molecular Medicine, Oncode Institute, University Medical Center Utrecht, Utrecht, The Netherlands.
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Źródło:
Nature [Nature] 2023 Jun; Vol. 618 (7964), pp. 333-341. Date of Electronic Publication: 2023 May 10.
Typ publikacji:
Comparative Study; Journal Article
MeSH Terms:
Genomics*
Neoplasm Metastasis*/genetics
Neoplasms*/genetics
Genome, Human*/genetics
Female ; Humans ; Male ; Disease Progression ; Mutation ; Cohort Studies ; Karyotyping ; APOBEC Deaminases/metabolism
Czasopismo naukowe
Tytuł:
NeuroImages: Sudden deafness due to bilateral auditory canal metastases.
Autorzy:
Lin J; Department of Neurology, The First Affiliated Hospital of Nanchang University, Nanchang 330000, Jiangxi, China.
Hong D; Department of Neurology, The First Affiliated Hospital of Nanchang University, Nanchang 330000, Jiangxi, China.
Li X; Department of Neurology, The First Affiliated Hospital of Nanchang University, Nanchang 330000, Jiangxi, China. Electronic address: .
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Źródło:
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia [J Clin Neurosci] 2023 Jun; Vol. 112, pp. 41-42. Date of Electronic Publication: 2023 Apr 11.
Typ publikacji:
Journal Article
MeSH Terms:
Hearing Loss, Sudden*/diagnostic imaging
Hearing Loss, Sudden*/etiology
Hearing Loss, Sudden*/pathology
Neoplasm Metastasis*
Humans ; Ear Canal
Czasopismo naukowe
Tytuł:
Metastasis prevention: How to catch metastatic seeds.
Autorzy:
Gerashchenko TS; Laboratory of Cancer Progression Biology, Cancer Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences, Kooperativny Str. 5, Tomsk 634009, Russia; Laboratory of Single Cell Biology, Research Institute of Molecular and Cellular Medicine, Рeoples' Friendship University of Russia (RUDN University), 6 Miklukho-Maklaya Str., Moscow 117198, Russia.
Schegoleva AA; Laboratory of Cancer Progression Biology, Cancer Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences, Kooperativny Str. 5, Tomsk 634009, Russia; Laboratory of Single Cell Biology, Research Institute of Molecular and Cellular Medicine, Рeoples' Friendship University of Russia (RUDN University), 6 Miklukho-Maklaya Str., Moscow 117198, Russia.
Khozyainova AA; Laboratory of Cancer Progression Biology, Cancer Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences, Kooperativny Str. 5, Tomsk 634009, Russia.
Choinzonov EL; Department of Head and Neck Cancer, Cancer Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences, Kooperativny Str. 5, Tomsk 634009, Russia.
Denisov EV; Laboratory of Cancer Progression Biology, Cancer Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences, Kooperativny Str. 5, Tomsk 634009, Russia; Laboratory of Single Cell Biology, Research Institute of Molecular and Cellular Medicine, Рeoples' Friendship University of Russia (RUDN University), 6 Miklukho-Maklaya Str., Moscow 117198, Russia. Electronic address: d_.
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Źródło:
Biochimica et biophysica acta. Reviews on cancer [Biochim Biophys Acta Rev Cancer] 2023 May; Vol. 1878 (3), pp. 188867. Date of Electronic Publication: 2023 Feb 24.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Neoplasms*/pathology
Neoplasm Metastasis*/diagnosis
Humans
Czasopismo naukowe
Tytuł:
Splicing factor SNRPA associated with microvascular invasion promotes hepatocellular carcinoma metastasis through activating NOTCH1/Snail pathway and is mediated by circSEC62/miR-625-5p axis.
Autorzy:
Mo Z; Fifth Department of General Surgery, The First Affiliated Hospital of Gannan Medical University, Ganzhou, China.; Department of Hepatobiliary Surgery, The Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China.
Li R; Department of Hepatobiliary and Pancreatic Surgery, The Eighth Affiliated Hospital, Sun Yat-Sen University, Shenzhen, China.
Cao C; Fifth Department of General Surgery, The First Affiliated Hospital of Gannan Medical University, Ganzhou, China.
Li Y; Department of Hepatobiliary Surgery, The Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China.
Zheng S; Department of Head and Neck surgery, Cancer Center of Guangzhou Medical University, Guangzhou, China.
Wu R; Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, China.
Xue J; Department of Physiology, School of Basic Medical Sciences, Gannan Medical University, Ganzhou, China.
Hu J; Department of Hepatobiliary Surgery, The Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China.
Meng H; Department of Hepatobiliary Surgery, The Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China.
Zhai H; Department of Hepatobiliary Surgery, The Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China.
Huang W; Department of Breast Oncology, State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Collaborative Innovation Center for Cancer Medicine, Guangzhou, China.
Zheng F; Medical Research Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China.
Zhou B; Department of Hepatobiliary Surgery, The Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China.
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Źródło:
Environmental toxicology [Environ Toxicol] 2023 May; Vol. 38 (5), pp. 1022-1037. Date of Electronic Publication: 2023 Jan 30.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Hepatocellular*/pathology
Liver Neoplasms*/pathology
MicroRNAs*/genetics
Neoplasm Metastasis*
RNA Splicing Factors*/genetics
RNA Splicing Factors*/metabolism
RNA, Circular*/metabolism
Humans ; Cell Line, Tumor ; Cell Movement ; Cell Proliferation ; Epithelial-Mesenchymal Transition/genetics ; Gene Expression Regulation, Neoplastic ; Peptides/genetics ; Peptides/metabolism ; Receptor, Notch1/genetics ; Receptor, Notch1/metabolism
Czasopismo naukowe
Tytuł:
Hydrogen Peroxide Induces α-Tubulin Detyrosination and Acetylation and Impacts Breast Cancer Metastatic Phenotypes.
Autorzy:
Stemberger MB; Graduate Program in Biochemistry and Molecular Biology, University of Maryland School of Medicine, 108 N. Greene St., Baltimore, MD 21201, USA.
Ju JA; Graduate Program in Molecular Medicine, University of Maryland School of Medicine, 800 W. Baltimore St., Baltimore, MD 21201, USA.
Thompson KN; Marlene and Stewart Greenebaum NCI Comprehensive Cancer Center, University of Maryland School of Medicine, 22 S. Greene St., Baltimore, MD 21201, USA.
Mathias TJ; Graduate Program in Molecular Medicine, University of Maryland School of Medicine, 800 W. Baltimore St., Baltimore, MD 21201, USA.
Jerrett AE; Marlene and Stewart Greenebaum NCI Comprehensive Cancer Center, University of Maryland School of Medicine, 22 S. Greene St., Baltimore, MD 21201, USA.
Chang KT; Graduate Program in Molecular Medicine, University of Maryland School of Medicine, 800 W. Baltimore St., Baltimore, MD 21201, USA.
Ory EC; Marlene and Stewart Greenebaum NCI Comprehensive Cancer Center, University of Maryland School of Medicine, 22 S. Greene St., Baltimore, MD 21201, USA.
Annis DA; Graduate Program in Epidemiology and Human Genetics, University of Maryland School of Medicine, 655 W. Baltimore St., Baltimore, MD 21201, USA.
Mull ML; Graduate Program in Molecular Medicine, University of Maryland School of Medicine, 800 W. Baltimore St., Baltimore, MD 21201, USA.
Gilchrist DE; Graduate Program in Molecular Medicine, University of Maryland School of Medicine, 800 W. Baltimore St., Baltimore, MD 21201, USA.
Vitolo MI; Graduate Program in Molecular Medicine, University of Maryland School of Medicine, 800 W. Baltimore St., Baltimore, MD 21201, USA.; Marlene and Stewart Greenebaum NCI Comprehensive Cancer Center, University of Maryland School of Medicine, 22 S. Greene St., Baltimore, MD 21201, USA.; Departments of Pharmacology and Physiology, University of Maryland School of Medicine, 655 W. Baltimore St., Baltimore, MD 21201, USA.
Martin SS; Graduate Program in Biochemistry and Molecular Biology, University of Maryland School of Medicine, 108 N. Greene St., Baltimore, MD 21201, USA.; Graduate Program in Molecular Medicine, University of Maryland School of Medicine, 800 W. Baltimore St., Baltimore, MD 21201, USA.; Marlene and Stewart Greenebaum NCI Comprehensive Cancer Center, University of Maryland School of Medicine, 22 S. Greene St., Baltimore, MD 21201, USA.; Graduate Program in Epidemiology and Human Genetics, University of Maryland School of Medicine, 655 W. Baltimore St., Baltimore, MD 21201, USA.; Departments of Pharmacology and Physiology, University of Maryland School of Medicine, 655 W. Baltimore St., Baltimore, MD 21201, USA.; United States Department of Veterans Affairs, VA Maryland Health Care System, 10 18 N. Greene St., Baltimore, MD 21201, USA.
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Źródło:
Cells [Cells] 2023 Apr 27; Vol. 12 (9). Date of Electronic Publication: 2023 Apr 27.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Tubulin*/metabolism
Breast Neoplasms*/pathology
Neoplasm Metastasis*
Humans ; Acetylation ; Hydrogen Peroxide ; MCF-7 Cells ; Protein Processing, Post-Translational
Czasopismo naukowe
Tytuł:
Genomic-transcriptomic evolution in lung cancer and metastasis.
Autorzy:
Martínez-Ruiz C; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.
Black JRM; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.
Puttick C; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute and University College London Cancer Institute, London, UK.
Hill MS; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute and University College London Cancer Institute, London, UK.
Demeulemeester J; Cancer Genomics Laboratory, The Francis Crick Institute, London, UK.; Integrative Cancer Genomics Laboratory, Department of Oncology, KU Leuven, Leuven, Belgium.; VIB-KU Leuven Center for Cancer Biology, Leuven, Belgium.
Larose Cadieux E; Cancer Genomics Laboratory, The Francis Crick Institute, London, UK.; Medical Genomics, University College London Cancer Institute, London, UK.
Thol K; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.
Jones TP; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.
Veeriah S; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.
Naceur-Lombardelli C; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.
Toncheva A; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.
Prymas P; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.
Rowan A; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute and University College London Cancer Institute, London, UK.
Ward S; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute and University College London Cancer Institute, London, UK.; Advanced Sequencing Facility, The Francis Crick Institute, London, UK.
Cubitt L; Advanced Sequencing Facility, The Francis Crick Institute, London, UK.
Athanasopoulou F; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute and University College London Cancer Institute, London, UK.; Advanced Sequencing Facility, The Francis Crick Institute, London, UK.
Pich O; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute and University College London Cancer Institute, London, UK.
Karasaki T; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute and University College London Cancer Institute, London, UK.; Cancer Metastasis Laboratory, University College London Cancer Institute, London, UK.
Moore DA; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute and University College London Cancer Institute, London, UK.; Department of Cellular Pathology, University College London Hospitals, London, UK.
Salgado R; Department of Pathology, ZAS Hospitals, Antwerp, Belgium.; Division of Research, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.
Colliver E; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute and University College London Cancer Institute, London, UK.
Castignani C; Cancer Genomics Laboratory, The Francis Crick Institute, London, UK.; Medical Genomics, University College London Cancer Institute, London, UK.
Dietzen M; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute and University College London Cancer Institute, London, UK.
Huebner A; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute and University College London Cancer Institute, London, UK.
Al Bakir M; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute and University College London Cancer Institute, London, UK.
Tanić M; Medical Genomics, University College London Cancer Institute, London, UK.; Experimental Oncology, Institute for Oncology and Radiology of Serbia, Belgrade, Serbia.
Watkins TBK; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute and University College London Cancer Institute, London, UK.
Lim EL; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute and University College London Cancer Institute, London, UK.
Al-Rashed AM; Centre for Nephrology, Division of Medicine, University College London, London, UK.
Lang D; Scientific Computing STP, Francis Crick Institute, London, UK.
Clements J; Scientific Computing STP, Francis Crick Institute, London, UK.
Cook DE; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute and University College London Cancer Institute, London, UK.
Rosenthal R; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute and University College London Cancer Institute, London, UK.
Wilson GA; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute and University College London Cancer Institute, London, UK.
Frankell AM; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute and University College London Cancer Institute, London, UK.
de Carné Trécesson S; Oncogene Biology Laboratory, The Francis Crick Institute, London, UK.
East P; Bioinformatics and Biostatistics, The Francis Crick Institute, London, UK.
Kanu N; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.
Litchfield K; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Tumour Immunogenomics and Immunosurveillance Laboratory, University College London Cancer Institute, London, UK.
Birkbak NJ; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute and University College London Cancer Institute, London, UK.; Department of Molecular Medicine, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.; Bioinformatics Research Centre, Aarhus University, Aarhus, Denmark.
Hackshaw A; Cancer Research UK & UCL Cancer Trials Centre, London, UK.
Beck S; Medical Genomics, University College London Cancer Institute, London, UK.
Van Loo P; Cancer Genomics Laboratory, The Francis Crick Institute, London, UK.; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Jamal-Hanjani M; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Metastasis Laboratory, University College London Cancer Institute, London, UK.; Department of Medical Oncology, University College London Hospitals, London, UK.
Swanton C; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK. .; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute and University College London Cancer Institute, London, UK. .; Department of Medical Oncology, University College London Hospitals, London, UK. .
McGranahan N; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK. .; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK. .
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Corporate Authors:
TRACERx Consortium
Źródło:
Nature [Nature] 2023 Apr; Vol. 616 (7957), pp. 543-552. Date of Electronic Publication: 2023 Apr 12.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Lung Neoplasms*/genetics
Lung Neoplasms*/pathology
Neoplasm Metastasis*/genetics
Transcriptome*/genetics
Evolution, Molecular*
Genome, Human*/genetics
Humans ; Carcinoma, Non-Small-Cell Lung/genetics ; Carcinoma, Non-Small-Cell Lung/pathology ; Genomics ; Mutation ; Alleles ; Machine Learning
Czasopismo naukowe
Tytuł:
Visually predicting microRNA-regulated tumor metastasis by intracellularly 3D counting of fluorescent spots based on in situ growth of DNA flares.
Autorzy:
Xue C; Cancer Metastasis Alert and Prevention Center, Fujian Provincial Key Laboratory of Cancer Metastasis Chemoprevention and Chemotherapy, Pharmaceutical Photocatalysis of State Key Laboratory of Photocatalysis on Energy and Environment, College of Chemistry, Fuzhou University, Fuzhou 350108, China.
Niu H; Cancer Metastasis Alert and Prevention Center, Fujian Provincial Key Laboratory of Cancer Metastasis Chemoprevention and Chemotherapy, Pharmaceutical Photocatalysis of State Key Laboratory of Photocatalysis on Energy and Environment, College of Chemistry, Fuzhou University, Fuzhou 350108, China; Fujian Key Laboratory of Aptamers Technology, The 900(th) Hospital of Joint Logistics Support Force, Fuzhou 350025, China.
Hu S; Cancer Metastasis Alert and Prevention Center, Fujian Provincial Key Laboratory of Cancer Metastasis Chemoprevention and Chemotherapy, Pharmaceutical Photocatalysis of State Key Laboratory of Photocatalysis on Energy and Environment, College of Chemistry, Fuzhou University, Fuzhou 350108, China.
Yang Z; Cancer Metastasis Alert and Prevention Center, Fujian Provincial Key Laboratory of Cancer Metastasis Chemoprevention and Chemotherapy, Pharmaceutical Photocatalysis of State Key Laboratory of Photocatalysis on Energy and Environment, College of Chemistry, Fuzhou University, Fuzhou 350108, China.
Wang L; Cancer Metastasis Alert and Prevention Center, Fujian Provincial Key Laboratory of Cancer Metastasis Chemoprevention and Chemotherapy, Pharmaceutical Photocatalysis of State Key Laboratory of Photocatalysis on Energy and Environment, College of Chemistry, Fuzhou University, Fuzhou 350108, China; Hunan Provincial Key Laboratory of Phytohormones and Growth Development, College of Bioscience and Biotechnology, Hunan Agricultural University, Changsha 410128, China.
Wu ZS; Cancer Metastasis Alert and Prevention Center, Fujian Provincial Key Laboratory of Cancer Metastasis Chemoprevention and Chemotherapy, Pharmaceutical Photocatalysis of State Key Laboratory of Photocatalysis on Energy and Environment, College of Chemistry, Fuzhou University, Fuzhou 350108, China. Electronic address: .
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Źródło:
Journal of advanced research [J Adv Res] 2023 Jan; Vol. 43, pp. 73-85. Date of Electronic Publication: 2022 Mar 04.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
DNA*/chemistry
MicroRNAs*/chemistry
MicroRNAs*/metabolism
Neoplasm Metastasis*/diagnostic imaging
Neoplasm Metastasis*/genetics
Animals ; Humans ; Mice ; Apoptosis Regulatory Proteins/metabolism ; HeLa Cells/metabolism ; Nanotechnology/methods ; RNA-Binding Proteins ; Fluorescent Dyes/chemistry
Czasopismo naukowe
Tytuł:
Direct interaction of platelet with tumor cell aggravates hepatocellular carcinoma metastasis by activating TLR4/ADAM10/CX3CL1 axis.
Autorzy:
Gao JH; Department of Pharmacology, School of Basic Medicine, Tongji Medical College and State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Huazhong University of Science and Technology, Wuhan, 430030, Hubei, China.
He AD; Department of Anatomy, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, 13 Hangkong Road, Wuhan, China.
Liu LM; Department of Pharmacology, School of Basic Medicine, Tongji Medical College and State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Huazhong University of Science and Technology, Wuhan, 430030, Hubei, China.
Zhou YJ; Department of Pharmacy, Hubei Provincial Hospital of Traditional Chinese Medicine, Hubei Province Academy of Traditional Chinese Medicine, Hubei University of Chinese Medicine, Wuhan, China.
Guo YW; Department of Pharmacology, School of Basic Medicine, Tongji Medical College and State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Huazhong University of Science and Technology, Wuhan, 430030, Hubei, China.
Lu M; Department of Pharmacology, School of Basic Medicine, Tongji Medical College and State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Huazhong University of Science and Technology, Wuhan, 430030, Hubei, China.
Zeng XB; Department of Pharmacology, School of Basic Medicine, Tongji Medical College and State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Huazhong University of Science and Technology, Wuhan, 430030, Hubei, China.
Gong X; Department of Pharmacology, School of Basic Medicine, Tongji Medical College and State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Huazhong University of Science and Technology, Wuhan, 430030, Hubei, China.
Lu YJ; Centre for Biomarkers and Therapeutics, Barts Cancer Institute, Queen Mary University of London, London, United Kingdom.
Liang HF; Hepatic Surgery Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Zhang BX; Hepatic Surgery Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Ma R; Department of Pharmacology, School of Basic Medicine, Tongji Medical College and State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Huazhong University of Science and Technology, Wuhan, 430030, Hubei, China.
Zhang RY; Hubei Key Laboratory of Diabetes and Angiopathy, Hubei University of Science and Technology, Xianning, China.
Ming ZY; Department of Pharmacology, School of Basic Medicine, Tongji Medical College and State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Huazhong University of Science and Technology, Wuhan, 430030, Hubei, China; Hubei Key Laboratory of Drug Target Research and Pharmacodynamic Evaluation, Wuhan, China; Tongji-Rongcheng Center for Biomedicine, Huazhong University of Science and Technology, Wuhan, China. Electronic address: .
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Źródło:
Cancer letters [Cancer Lett] 2024 Mar 31; Vol. 585, pp. 216674. Date of Electronic Publication: 2024 Jan 25.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Hepatocellular*/pathology
Liver Neoplasms*/pathology
Animals ; Mice ; Humans ; Toll-Like Receptor 4/metabolism ; Epithelial-Mesenchymal Transition ; Signal Transduction ; ADAM10 Protein/metabolism ; Cell Movement ; Cell Line, Tumor ; Neoplasm Metastasis ; Membrane Proteins/metabolism ; Amyloid Precursor Protein Secretases/metabolism ; Chemokine CX3CL1
Czasopismo naukowe

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