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Tytuł:
FOXO3a‑modulated DEPDC1 promotes malignant progression of nephroblastoma via the Wnt/β‑catenin signaling pathway.
Autorzy:
Geng G; Department of Pediatric Surgery, Taian City Central Hospital, Taian, Shandong 271000, P.R. China.
Li Q; Department of Pediatric Surgery, Taian City Central Hospital, Taian, Shandong 271000, P.R. China.
Guo X; Department of Pediatric Respirology and Cardiology, The Affiliated Hospital of Qingdao University, Qingdao 266000, P.R. China.
Ni Q; Department of Pediatric Surgery, Taian City Central Hospital, Taian, Shandong 271000, P.R. China.
Xu Y; Department of Pediatric Surgery, Taian City Central Hospital, Taian, Shandong 271000, P.R. China.
Ma Z; Department of Pediatric Surgery, Taian City Central Hospital, Taian, Shandong 271000, P.R. China.
Wang Y; Department of Pediatric Surgery, Taian City Central Hospital, Taian, Shandong 271000, P.R. China.
Ming M; Department of Pediatric Surgery, Taian City Central Hospital, Taian, Shandong 271000, P.R. China.
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Źródło:
Molecular medicine reports [Mol Med Rep] 2022 Aug; Vol. 26 (2). Date of Electronic Publication: 2022 Jul 07.
Typ publikacji:
Journal Article
MeSH Terms:
Forkhead Box Protein O3*/genetics
Forkhead Box Protein O3*/metabolism
GTPase-Activating Proteins*/genetics
GTPase-Activating Proteins*/metabolism
Neoplasm Proteins*/genetics
Neoplasm Proteins*/metabolism
Wilms Tumor*/genetics
Wilms Tumor*/metabolism
Wnt Signaling Pathway*
Cell Proliferation/physiology ; Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Low-dose hexavalent chromium(VI) exposure promotes prostate cancer cell proliferation by activating MAGEB2-AR signal pathway.
Autorzy:
Qie Y; Department of Urology, Tianjin Institute of Urology, The Second Hospital of Tianjin Medical University, Tianjin 300211, China; CAS Key Laboratory for Biomedical Effects of Nanomaterials & Nanosafety, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, Beijing 100190, China.
Zhou D; Department of Urology, Tianjin Institute of Urology, The Second Hospital of Tianjin Medical University, Tianjin 300211, China.
Wu Z; Department of Urology, Tianjin Institute of Urology, The Second Hospital of Tianjin Medical University, Tianjin 300211, China.
Liu S; Department of Urology, Tianjin Institute of Urology, The Second Hospital of Tianjin Medical University, Tianjin 300211, China.
Shen C; Department of Urology, Tianjin Institute of Urology, The Second Hospital of Tianjin Medical University, Tianjin 300211, China.
Hu H; Department of Urology, Tianjin Institute of Urology, The Second Hospital of Tianjin Medical University, Tianjin 300211, China.
Zhang C; Department of Urology, Tianjin Institute of Urology, The Second Hospital of Tianjin Medical University, Tianjin 300211, China. Electronic address: .
Xu Y; Department of Urology, Tianjin Institute of Urology, The Second Hospital of Tianjin Medical University, Tianjin 300211, China. Electronic address: .
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Źródło:
Ecotoxicology and environmental safety [Ecotoxicol Environ Saf] 2022 Aug; Vol. 241, pp. 113724. Date of Electronic Publication: 2022 Jun 02.
Typ publikacji:
Journal Article
MeSH Terms:
Antigens, Neoplasm*/genetics
Antigens, Neoplasm*/metabolism
Carcinogens, Environmental*/toxicity
Neoplasm Proteins*/genetics
Neoplasm Proteins*/metabolism
Prostatic Neoplasms*/genetics
Prostatic Neoplasms*/metabolism
Cell Proliferation/drug effects ; Chromium/toxicity ; Humans ; Male ; Receptors, Androgen/metabolism ; Signal Transduction/drug effects
Czasopismo naukowe
Szczegóły
Tytuł:
Transporter hypothesis in pharmacoresistant epilepsies. Is it at the central or peripheral level?
Autorzy:
Czornyj L; Neurology Service, 'Juan P. Garrahan' National Children's Hospital, Buenos Aires, Argentina.
Auzmendi J; Institute for Research in Physiopathology and Clinical Biochemistry (INFIBIOC), Clinical Biochemistry Department, School of Pharmacy and Biochemistry, University of Buenos Aires, Buenos Aires, Argentina.; National Council for Scientific and Technical Research (CONICET), Buenos Aires, Argentina.
Lazarowski A; Institute for Research in Physiopathology and Clinical Biochemistry (INFIBIOC), Clinical Biochemistry Department, School of Pharmacy and Biochemistry, University of Buenos Aires, Buenos Aires, Argentina.
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Źródło:
Epilepsia open [Epilepsia Open] 2022 Aug; Vol. 7 Suppl 1, pp. S34-S46. Date of Electronic Publication: 2021 Oct 29.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Epilepsy*/drug therapy
Neoplasm Proteins*/genetics
Neoplasm Proteins*/metabolism
Neoplasm Proteins*/therapeutic use
ATP Binding Cassette Transporter, Subfamily B, Member 1/genetics ; ATP Binding Cassette Transporter, Subfamily B, Member 1/metabolism ; ATP Binding Cassette Transporter, Subfamily B, Member 1/therapeutic use ; ATP Binding Cassette Transporter, Subfamily G, Member 2/metabolism ; ATP-Binding Cassette Transporters/genetics ; ATP-Binding Cassette Transporters/metabolism ; ATP-Binding Cassette Transporters/therapeutic use ; Humans ; Seizures/drug therapy ; Tissue Distribution
Czasopismo naukowe
Szczegóły
Tytuł:
TM4SF1 promotes esophageal squamous cell carcinoma metastasis by interacting with integrin α6.
Autorzy:
Hou S; Department of Gastroenterology, The Affiliated Hospital of Yangzhou University, Yangzhou University, 225009, Yangzhou, Jiangsu, China. .
Hao X; Department of Gastroenterology, The Affiliated Hospital of Yangzhou University, Yangzhou University, 225009, Yangzhou, Jiangsu, China.; Department of Clinical Medicine, Medical College, Yangzhou University, 225001, Yangzhou, Jiangsu, China.
Li J; Department of Gastroenterology, The Affiliated Hospital of Yangzhou University, Yangzhou University, 225009, Yangzhou, Jiangsu, China.
Weng S; Department of stomatology, Clinical Traditional Chinese Medicine College of Yangzhou University, 225000, Yangzhou, Jiangsu, China.
Wang J; Department of Clinical Medicine, Medical College, Yangzhou University, 225001, Yangzhou, Jiangsu, China.
Zhao T; Department of Clinical Medicine, Medical College, Yangzhou University, 225001, Yangzhou, Jiangsu, China.
Li W; Department of Clinical Medicine, Medical College, Yangzhou University, 225001, Yangzhou, Jiangsu, China.
Hu X; Department of Clinical Medicine, Medical College, Yangzhou University, 225001, Yangzhou, Jiangsu, China.
Deng B; Department of Gastroenterology, The Affiliated Hospital of Yangzhou University, Yangzhou University, 225009, Yangzhou, Jiangsu, China.
Gu J; Division of Regulatory Glycobiology, Institute of Molecular Biomembrane and Glycobiology, Tohoku Medical and Pharmaceutical University, Sendai, Miyagi, 981-8558, Japan. .
Hang Q; Division of Regulatory Glycobiology, Institute of Molecular Biomembrane and Glycobiology, Tohoku Medical and Pharmaceutical University, Sendai, Miyagi, 981-8558, Japan. .; Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA. .
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Źródło:
Cell death & disease [Cell Death Dis] 2022 Jul 14; Vol. 13 (7), pp. 609. Date of Electronic Publication: 2022 Jul 14.
Typ publikacji:
Journal Article
MeSH Terms:
Antigens, Surface*/genetics
Antigens, Surface*/metabolism
Esophageal Neoplasms*/genetics
Esophageal Neoplasms*/metabolism
Esophageal Neoplasms*/pathology
Esophageal Squamous Cell Carcinoma*/genetics
Esophageal Squamous Cell Carcinoma*/metabolism
Esophageal Squamous Cell Carcinoma*/pathology
Integrin alpha6*/genetics
Integrin alpha6*/metabolism
Neoplasm Proteins*/genetics
Neoplasm Proteins*/metabolism
Cell Line, Tumor ; Cell Movement/genetics ; Gene Expression Regulation, Neoplastic/genetics ; Humans ; Laminin/genetics ; Laminin/metabolism ; Neoplasm Invasiveness
Czasopismo naukowe
Szczegóły
Tytuł:
Tumor protein D54 binds intracellular nanovesicles via an extended amphipathic region.
Autorzy:
Reynaud A; Université Côte d'Azur et CNRS, Institut de Pharmacologie Moléculaire et Cellulaire, Valbonne, France.
Magdeleine M; Université Côte d'Azur et CNRS, Institut de Pharmacologie Moléculaire et Cellulaire, Valbonne, France.
Patel A; Université Côte d'Azur et CNRS, Institut de Pharmacologie Moléculaire et Cellulaire, Valbonne, France.
Gay AS; Université Côte d'Azur et CNRS, Institut de Pharmacologie Moléculaire et Cellulaire, Valbonne, France.
Debayle D; Université Côte d'Azur et CNRS, Institut de Pharmacologie Moléculaire et Cellulaire, Valbonne, France.
Abelanet S; Université Côte d'Azur et CNRS, Institut de Pharmacologie Moléculaire et Cellulaire, Valbonne, France.
Antonny B; Université Côte d'Azur et CNRS, Institut de Pharmacologie Moléculaire et Cellulaire, Valbonne, France. Electronic address: .
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Źródło:
The Journal of biological chemistry [J Biol Chem] 2022 Jul; Vol. 298 (7), pp. 102136. Date of Electronic Publication: 2022 Jun 14.
Typ publikacji:
Journal Article
MeSH Terms:
Liposomes*/chemistry
Neoplasm Proteins*/genetics
Neoplasm Proteins*/metabolism
Lipids ; Membranes/metabolism ; Protein Binding ; Transport Vesicles/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
Cancer germline antigen gene MAGEB2 promotes cell invasion and correlates with immune microenvironment and immunotherapeutic efficiency in laryngeal cancer.
Autorzy:
Cui J; Department of Head and Neck Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Shenzhen 518116, Guangdong Province, PR China.
Chen Y; Department of Radiation Oncology, Affiliated Cancer Hospital & Institute of Guangzhou Medical University, Guangzhou 510095, Guangdong Province, PR China.
Ou Y; Department of Oncology, Huizhou Third People's Hospital, Guangzhou Medical University, Huizhou 516000, Guangdong Province, PR China.
Liu G; Department of Pathology, The Third Affiliated Hospital of Guangdong Medical University (Longjiang Hospital of Shunde District), Foshan 528318, Guangdong Province, PR China.
Wen Q; Department of Head and Neck Surgery, Affiliated Cancer Hospital & Institute of Guangzhou Medical University, Guangzhou 510095, Guangdong Province, PR China.
Zhu W; Department of Head and Neck Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Shenzhen 518116, Guangdong Province, PR China.
Liang L; Department of Head and Neck Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Shenzhen 518116, Guangdong Province, PR China.
Chen Z; Department of Intensive Care Unit, Shunde Hospital, Southern Medical University (The First people's hospital of Shunde), Foshan 528308, Guangdong Province, PR China. Electronic address: .
Yang H; Department of Head and Neck Surgery, Affiliated Cancer Hospital & Institute of Guangzhou Medical University, Guangzhou 510095, Guangdong Province, PR China. Electronic address: .
Wang L; Department of Otorhinolaryngology Head and Neck Surgery, The First Affiliated Hospital of Hainan Medical University, Haikou 570102, Hainan Province, PR China. Electronic address: .
Wei M; Department of Head and Neck Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Shenzhen 518116, Guangdong Province, PR China. Electronic address: .
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Źródło:
Clinical immunology (Orlando, Fla.) [Clin Immunol] 2022 Jul; Vol. 240, pp. 109045. Date of Electronic Publication: 2022 May 23.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antigens, Neoplasm*/genetics
Antigens, Neoplasm*/metabolism
Laryngeal Neoplasms*/genetics
Laryngeal Neoplasms*/metabolism
Laryngeal Neoplasms*/pathology
Laryngeal Neoplasms*/therapy
Lung Neoplasms*/genetics
Lung Neoplasms*/metabolism
Lung Neoplasms*/pathology
Lung Neoplasms*/therapy
Neoplasm Proteins*/genetics
Neoplasm Proteins*/metabolism
Animals ; Cell Line, Tumor ; Germ Cells/metabolism ; Germ Cells/pathology ; Humans ; Immunotherapy ; Prognosis ; Tumor Microenvironment/genetics
Czasopismo naukowe
Szczegóły
Tytuł:
A cooperative mechanism of target RNA selection via germ-cell-specific RNA-binding proteins NANOS2 and DND1.
Autorzy:
Hirano T; Mammalian Development Laboratory, Department of Gene Function and Phenomics, National Institute of Genetics, 1111 Mishima, Shizuoka 411-8582, Japan.
Wright D; Mammalian Development Laboratory, Department of Gene Function and Phenomics, National Institute of Genetics, 1111 Mishima, Shizuoka 411-8582, Japan; Department of Genetics, SOKENDAI, 1111 Mishima, Shizuoka 411-8582, Japan.
Suzuki A; Division of Materials Science and Chemical Engineering, Graduate School of Engineering, Yokohama National University, Yokohama, Kanagawa 240-8501 Japan.
Saga Y; Mammalian Development Laboratory, Department of Gene Function and Phenomics, National Institute of Genetics, 1111 Mishima, Shizuoka 411-8582, Japan; Department of Genetics, SOKENDAI, 1111 Mishima, Shizuoka 411-8582, Japan; Division for Development of Genetic-Engineered Mouse Resource, Genetic Resource Center, National Institute of Genetics, 1111 Mishima, Shizuoka 411-8582, Japan; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan. Electronic address: .
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Źródło:
Cell reports [Cell Rep] 2022 Jun 14; Vol. 39 (11), pp. 110894.
Typ publikacji:
Journal Article
MeSH Terms:
Germ Cells*/metabolism
Neoplasm Proteins*/genetics
Neoplasm Proteins*/metabolism
RNA*/metabolism
RNA-Binding Proteins*/genetics
RNA-Binding Proteins*/metabolism
Cell Differentiation ; Humans ; Male ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Transcription Factors
Czasopismo naukowe
Szczegóły
Tytuł:
Involvement of TMEM16A/ANO1 upregulation in the oncogenesis of colorectal cancer.
Autorzy:
Yan Y; Department of Pharmacology, School of Pharmacy, Qingdao University Medical College, 1 Ningde Road, Qingdao 266073, China; Department of Outpatient and Emergency, the Affiliated Hospital of Qingdao University, 16 Jiangsu Road, Qingdao 266000, China.
Ding X; School of Basic Medicine and Institute of Stem Cell and Regenerative Medicine, Qingdao University Medical College, 1 Ningde Road, Qingdao 266073, China.
Han C; Department of Clinical Laboratory, the Affiliated Hospital of Qingdao University, 16 Jiangsu Road, Qingdao 266000, China.
Gao J; Department of Pharmacology, School of Pharmacy, Qingdao University Medical College, 1 Ningde Road, Qingdao 266073, China; Institute of Innovative Drugs, Qingdao University, 38 Dengzhou Road, Qingdao 266021, China.
Liu Z; Department of Clinical Laboratory, Qingdao Third People's Hospital, 29 Yongping Road, Qingdao 266041, China.
Liu Y; Department of Pharmacology, School of Pharmacy, Qingdao University Medical College, 1 Ningde Road, Qingdao 266073, China; Institute of Innovative Drugs, Qingdao University, 38 Dengzhou Road, Qingdao 266021, China.. Electronic address: .
Wang K; Department of Pharmacology, School of Pharmacy, Qingdao University Medical College, 1 Ningde Road, Qingdao 266073, China; Institute of Innovative Drugs, Qingdao University, 38 Dengzhou Road, Qingdao 266021, China.. Electronic address: .
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Źródło:
Biochimica et biophysica acta. Molecular basis of disease [Biochim Biophys Acta Mol Basis Dis] 2022 Jun 01; Vol. 1868 (6), pp. 166370. Date of Electronic Publication: 2022 Feb 26.
Typ publikacji:
Journal Article
MeSH Terms:
Anoctamin-1*/genetics
Anoctamin-1*/metabolism
Colorectal Neoplasms*/genetics
Colorectal Neoplasms*/pathology
Neoplasm Proteins*/genetics
Neoplasm Proteins*/metabolism
Animals ; Carcinogenesis/genetics ; HT29 Cells ; Humans ; Mice ; Mice, Nude ; Up-Regulation
Czasopismo naukowe
Szczegóły
Tytuł:
The role of microvesicles as biomarkers in the screening of colorectal neoplasm.
Autorzy:
Eddama MMR; Research Department of Surgical Biotechnology, Division of Surgery and Interventional Science, University College London, London, UK.; Department of Surgery, University College London Hospital, London, UK.
Gurung R; Research Department of Surgical Biotechnology, Division of Surgery and Interventional Science, University College London, London, UK.
Fragkos K; Department of Gastroenterology, University College London Hospital, London, UK.
Lorgelly P; Department of Applied Health Research, Institute of Epidemiology and Health, University College London, London, UK.
Cohen R; Research Department of Surgical Biotechnology, Division of Surgery and Interventional Science, University College London, London, UK.; Department of Surgery, University College London Hospital, London, UK.
Loizidou M; Research Department of Surgical Biotechnology, Division of Surgery and Interventional Science, University College London, London, UK.
Clapp L; Institute of Cardiovascular Sciences, University College London, London, UK.
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Źródło:
Cancer medicine [Cancer Med] 2022 Aug; Vol. 11 (15), pp. 2957-2968. Date of Electronic Publication: 2022 Mar 27.
Typ publikacji:
Journal Article
MeSH Terms:
Colorectal Neoplasms*/diagnosis
Neoplasm Proteins*
ATP Binding Cassette Transporter, Subfamily G, Member 2 ; Biomarkers ; Biomarkers, Tumor ; Humans ; Mass Screening
Czasopismo naukowe
Szczegóły
Tytuł:
SUZ12 participates in the proliferation of PNH clones by regulating histone H3K27me3 levels.
Autorzy:
Chen Y; Department of Hematology, Tianjin Medical University General Hospital, Tianjin, China.
Liu H; Department of Hematology, Tianjin Medical University General Hospital, Tianjin, China.
Zeng L; Department of Hematology, Tianjin Medical University General Hospital, Tianjin, China.
Li L; Department of Hematology, Tianjin Medical University General Hospital, Tianjin, China.
Lu D; Department of Hematology, Tianjin Medical University General Hospital, Tianjin, China.
Liu Z; Department of Hematology, Tianjin Medical University General Hospital, Tianjin, China.
Fu R; Department of Hematology, Tianjin Medical University General Hospital, Tianjin, China.
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Źródło:
Journal of leukocyte biology [J Leukoc Biol] 2022 Aug; Vol. 112 (2), pp. 243-255. Date of Electronic Publication: 2022 Jan 06.
Typ publikacji:
Journal Article
MeSH Terms:
Hemoglobinuria, Paroxysmal*/genetics
Hemoglobinuria, Paroxysmal*/metabolism
Hemoglobinuria, Paroxysmal*/therapy
Histones*
Neoplasm Proteins*/genetics
Transcription Factors*/genetics
Cell Proliferation ; Clone Cells/metabolism ; Humans
Czasopismo naukowe
Szczegóły
Tytuł:
Protocol for profiling cell-centric assembled single-cell human transcriptome data in hECA.
Autorzy:
Chen Y; MOE Key Lab of Bioinformatics, Bioinformatics Division of BNRIST and Department of Automation, Tsinghua University, Beijing 100084, China.
Hao M; MOE Key Lab of Bioinformatics, Bioinformatics Division of BNRIST and Department of Automation, Tsinghua University, Beijing 100084, China.
Gao H; MOE Key Lab of Bioinformatics, Bioinformatics Division of BNRIST and Department of Automation, Tsinghua University, Beijing 100084, China.
Li J; MOE Key Lab of Bioinformatics, Bioinformatics Division of BNRIST and Department of Automation, Tsinghua University, Beijing 100084, China.
Chen S; MOE Key Lab of Bioinformatics, Bioinformatics Division of BNRIST and Department of Automation, Tsinghua University, Beijing 100084, China.
Li F; MOE Key Lab of Bioinformatics, Bioinformatics Division of BNRIST and Department of Automation, Tsinghua University, Beijing 100084, China.
Wei L; MOE Key Lab of Bioinformatics, Bioinformatics Division of BNRIST and Department of Automation, Tsinghua University, Beijing 100084, China.
Zhang X; MOE Key Lab of Bioinformatics, Bioinformatics Division of BNRIST and Department of Automation, Tsinghua University, Beijing 100084, China.; School of Medicine, Tsinghua University, Beijing 100084, China.; School of Life Sciences, Center for Synthetic and Systems Biology, Tsinghua University, Beijing 100084, China.
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Źródło:
STAR protocols [STAR Protoc] 2022 Jul 31; Vol. 3 (3), pp. 101589. Date of Electronic Publication: 2022 Jul 31 (Print Publication: 2022).
Typ publikacji:
Journal Article
MeSH Terms:
Neoplasm Proteins*
Transcriptome*/genetics
Humans
Czasopismo naukowe
Szczegóły
Tytuł:
Developing an In Vitro to In Vivo Extrapolation (IVIVE) Model to Predict Human Milk-to-Plasma Drug Concentration Ratios.
Autorzy:
Yang H; Office of Clinical Pharmacology, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, 10903 New Hampshire Avenue, Silver Spring, Maryland 20993, United States.
Xue I; Office of Clinical Pharmacology, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, 10903 New Hampshire Avenue, Silver Spring, Maryland 20993, United States.
Gu Q; Office of Clinical Pharmacology, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, 10903 New Hampshire Avenue, Silver Spring, Maryland 20993, United States.
Zou P; Office of Clinical Pharmacology, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, 10903 New Hampshire Avenue, Silver Spring, Maryland 20993, United States.
Zhang T; Department of Pharmaceutical Sciences, Binghamton University-SUNY, 96 Corliss Ave, Johnson City, New York 13790, United States.
Lu Y; Office of Clinical Pharmacology, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, 10903 New Hampshire Avenue, Silver Spring, Maryland 20993, United States.
Fisher J; ScitoVation, 6 Davis Drive, Suite 146, Durham, North Carolina 27709, United States.
Tran D; Office of Clinical Pharmacology, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, 10903 New Hampshire Avenue, Silver Spring, Maryland 20993, United States.
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Źródło:
Molecular pharmaceutics [Mol Pharm] 2022 Jul 04; Vol. 19 (7), pp. 2506-2517. Date of Electronic Publication: 2022 Jun 08.
Typ publikacji:
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:
Milk, Human*/metabolism
Neoplasm Proteins*/metabolism
ATP Binding Cassette Transporter, Subfamily G, Member 2/metabolism ; Biological Transport ; Caco-2 Cells ; Humans ; Models, Biological
Czasopismo naukowe
Szczegóły
Tytuł:
Integrative analysis of genomic and transcriptomic alterations of AGR2 and AGR3 in cancer.
Autorzy:
Fessart D; ARTiSt, University Bordeaux, INSERM U1312, Bordeaux F-33000, France.; POETIC, University Bordeaux, INSERM U1312, Bordeaux F-33000, France.
Villamor I; POETIC, University Bordeaux, INSERM U1312, Bordeaux F-33000, France.
Chevet E; INSERM U1242, 'Chemistry, Oncogenesis Stress Signaling', Université Rennes 1, Rennes, France.; Centre de Lutte Contre le Cancer Eugène Marquis, Rennes, France.
Delom F; ARTiSt, University Bordeaux, INSERM U1312, Bordeaux F-33000, France.
Robert J; ARTiSt, University Bordeaux, INSERM U1312, Bordeaux F-33000, France.
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Źródło:
Open biology [Open Biol] 2022 Jul; Vol. 12 (7), pp. 220068. Date of Electronic Publication: 2022 Jul 13.
Typ publikacji:
Journal Article
MeSH Terms:
Adenocarcinoma*/genetics
Neoplasm Proteins*/metabolism
Carrier Proteins/metabolism ; DNA Copy Number Variations ; Gene Expression Regulation, Neoplastic ; Genomics ; Humans ; Mucoproteins/genetics ; Mucoproteins/metabolism ; Oncogene Proteins/genetics ; Oncogene Proteins/metabolism ; RNA, Messenger ; Transcriptome
Czasopismo naukowe
Szczegóły
Tytuł:
OCA-T1 and OCA-T2 are coactivators of POU2F3 in the tuft cell lineage.
Autorzy:
Wu XS; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.; Genetics Program, Stony Brook University, Stony Brook, NY, USA.
He XY; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.
Ipsaro JJ; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.; Howard Hughes Medical Institute, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.
Huang YH; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.
Preall JB; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.
Ng D; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.
Shue YT; Department of Pediatrics, Stanford University, Stanford, CA, USA.; Department of Genetics, Stanford University, Stanford, CA, USA.
Sage J; Department of Pediatrics, Stanford University, Stanford, CA, USA.; Department of Genetics, Stanford University, Stanford, CA, USA.
Egeblad M; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.
Joshua-Tor L; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.; Howard Hughes Medical Institute, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.
Vakoc CR; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA. .
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Źródło:
Nature [Nature] 2022 Jul; Vol. 607 (7917), pp. 169-175. Date of Electronic Publication: 2022 May 16.
Typ publikacji:
Journal Article
MeSH Terms:
Cell Lineage*
Lung Neoplasms*/pathology
Neoplasm Proteins*/metabolism
Octamer Transcription Factors*/metabolism
Small Cell Lung Carcinoma*/pathology
Animals ; Humans ; Mice ; Mucous Membrane/pathology ; Multigene Family/genetics ; Nucleotide Motifs ; POU Domain Factors/metabolism ; Trans-Activators
Czasopismo naukowe
Szczegóły
Tytuł:
Placental and plasma early predictive biomarkers for gestational diabetes mellitus.
Autorzy:
Wei Y; Department of Obstetrics and Gynecology, The First Affiliated Hospital of Jinan University, Guangzhou, China.
He A; Department of Obstetrics and Gynecology, The First Affiliated Hospital of Jinan University, Guangzhou, China.
Huang Z; Department of Obstetrics and Gynecology, The First Affiliated Hospital of Jinan University, Guangzhou, China.
Liu J; Department of Obstetrics and Gynecology, The First Affiliated Hospital of Jinan University, Guangzhou, China.
Li R; Department of Obstetrics and Gynecology, The First Affiliated Hospital of Jinan University, Guangzhou, China.
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Źródło:
Proteomics. Clinical applications [Proteomics Clin Appl] 2022 Jul; Vol. 16 (4), pp. e2200001. Date of Electronic Publication: 2022 Apr 14.
Typ publikacji:
Journal Article
MeSH Terms:
Antigens, CD*
Diabetes, Gestational*/metabolism
Neoplasm Proteins*
Antigens, Neoplasm ; Biomarkers/metabolism ; Female ; GPI-Linked Proteins ; Humans ; Placenta/metabolism ; Pregnancy ; Proteome ; Proteomics
Czasopismo naukowe
Szczegóły
Tytuł:
Knockdown of MAGE-A6 enhanced the irradiation sensitivity of non-small cell lung cancer cells by activating the AMPK pathway.
Autorzy:
Zhou J; Department of Radiation Oncology, Affiliated Hospital of Jiangnan University, Wuxi, China.
Fan Q; Department of Radiation Oncology, Affiliated Hospital of Jiangnan University, Wuxi, China.
Li J; Department of Interventional Radiology, Affiliated Hospital of Jiangnan University, Wuxi, China.
Wu J; Department of Radiation Oncology, Affiliated Hospital of Jiangnan University, Wuxi, China.
Huang J; Department of Radiation Oncology, Affiliated Hospital of Jiangnan University, Wuxi, China.
Zhang Y; Department of Radiation Oncology, Affiliated Hospital of Jiangnan University, Wuxi, China.
He X; Department of Oncology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China.
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Źródło:
Environmental toxicology [Environ Toxicol] 2022 Jul; Vol. 37 (7), pp. 1711-1722. Date of Electronic Publication: 2022 Mar 14.
Typ publikacji:
Journal Article
MeSH Terms:
AMP-Activated Protein Kinases*/metabolism
Antigens, Neoplasm*/genetics
Carcinoma, Non-Small-Cell Lung*/metabolism
Carcinoma, Non-Small-Cell Lung*/pathology
Lung Neoplasms*/metabolism
Lung Neoplasms*/pathology
Neoplasm Proteins*/genetics
Radiation Tolerance*/genetics
Animals ; Apoptosis/radiation effects ; Cell Line, Tumor ; Cell Proliferation ; Humans ; Mice ; Mice, Nude
Czasopismo naukowe
Szczegóły
Tytuł:
TMEM16A overexpression indicates poor prognosis in colorectal cancer patients.
Autorzy:
Liu JJ; Gastroenterology, The First Affiliated Hospital of Dalian Medical University.
He F; Gastroenterology, The First Affiliated Hospital of Dalian Medical University.
Guo SB; Gastroenterology, The First Affiliated Hospital of Dalian Medical University, China.
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Źródło:
Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva [Rev Esp Enferm Dig] 2022 Jul; Vol. 114 (7), pp. 390-394.
Typ publikacji:
Journal Article
MeSH Terms:
Colorectal Neoplasms*/pathology
Anoctamin-1/*metabolism
Neoplasm Proteins/*metabolism
Anoctamin-1/analysis ; Biomarkers, Tumor/analysis ; Humans ; Kaplan-Meier Estimate ; Lymphatic Metastasis ; Neoplasm Proteins/analysis ; Neoplasm Staging ; Prognosis
Czasopismo naukowe
Szczegóły
Tytuł:
Clinicopathological assessment of cancer/testis antigens NY‑ESO‑1 and MAGE‑A4 in osteosarcoma.
Autorzy:
Hashimoto K; Department of Orthopedic Surgery, Kindai University Hospital, Osaka-Sayama City, Osaka. .
Nishimura S; Department of Orthopedic Surgery, Kindai University Hospital, Osaka-Sayama City, Osaka. .
Ito T; Department of Orthopedic Surgery, Kindai University Hospital, Osaka-Sayama City, Osaka. .
Oka N; Department of Orthopedic Surgery, Kindai University Hospital, Osaka-Sayama City, Osaka. .
Kakinoki R; Department of Orthopedic Surgery, Kindai University Hospital, Osaka-Sayama City, Osaka. .
Akagi M; Department of Orthopedic Surgery, Kindai University Hospital, Osaka-Sayama City, Osaka. .
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Źródło:
European journal of histochemistry : EJH [Eur J Histochem] 2022 Jun 23; Vol. 66 (3). Date of Electronic Publication: 2022 Jun 23.
Typ publikacji:
Journal Article
MeSH Terms:
Antigens, Neoplasm*/genetics
Bone Neoplasms*/genetics
Membrane Proteins*/genetics
Neoplasm Proteins*/genetics
Osteosarcoma*/genetics
Adult ; Biomarkers, Tumor/genetics ; Humans ; Ki-67 Antigen/genetics ; Male ; Prognosis ; Tumor Suppressor Protein p53
Czasopismo naukowe
Szczegóły
Tytuł:
Investigation of the Uptake and Transport of Two Novel Camptothecin Derivatives in Caco-2 Cell Monolayers.
Autorzy:
Wang Y; College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310032, China.
Zhang X; College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310032, China.
Zhuang W; College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310032, China.
Yu Y; College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310032, China.
Sun X; College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310032, China.
Wang H; College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310032, China.
Li F; Department of Pharmacology and Therapeutics, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.
Li Q; College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310032, China.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2022 Jun 07; Vol. 27 (12). Date of Electronic Publication: 2022 Jun 07.
Typ publikacji:
Journal Article
MeSH Terms:
Camptothecin*/analogs & derivatives
Camptothecin*/metabolism
Neoplasm Proteins*/metabolism
ATP Binding Cassette Transporter, Subfamily B, Member 1/metabolism ; ATP Binding Cassette Transporter, Subfamily G, Member 2 ; Biological Transport ; Caco-2 Cells ; Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Interference of PTK6/GAB1 signaling inhibits cell proliferation, invasion, and migration of cervical cancer cells.
Autorzy:
Li J; Department of Gynecology, Southern University of Science and Technology Hospital, Shenzhen, Guangdong 518055, P.R. China.
Yang N; Department of Gynecology, Southern University of Science and Technology Hospital, Shenzhen, Guangdong 518055, P.R. China.
Tian X; Department of Gynecology, Southern University of Science and Technology Hospital, Shenzhen, Guangdong 518055, P.R. China.
Ouyang L; Department of Gynecology, Southern University of Science and Technology Hospital, Shenzhen, Guangdong 518055, P.R. China.
Jiang M; Department of Gynecology, Southern University of Science and Technology Hospital, Shenzhen, Guangdong 518055, P.R. China.
Zhang S; Department of Gynecology, Southern University of Science and Technology Hospital, Shenzhen, Guangdong 518055, P.R. China.
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Źródło:
Molecular medicine reports [Mol Med Rep] 2022 Sep; Vol. 26 (3). Date of Electronic Publication: 2022 Jul 27.
Typ publikacji:
Journal Article
MeSH Terms:
Adaptor Proteins, Signal Transducing*/genetics
Adaptor Proteins, Signal Transducing*/metabolism
Neoplasm Proteins*/genetics
Neoplasm Proteins*/metabolism
Protein-Tyrosine Kinases*/genetics
Protein-Tyrosine Kinases*/metabolism
Uterine Cervical Neoplasms*/genetics
Apoptosis/genetics ; Cell Line, Tumor ; Cell Movement/genetics ; Cell Proliferation ; Female ; Humans ; Signal Transduction
Czasopismo naukowe
Szczegóły
Wyświetlanie 1-20 z 36098

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